Alp Üçok, Handan Noyan, Sinan Gülöksüz, Meram Can Saka, Köksal Alptekin, Cem Atbaşoğlu, Elçin Akturan, Gülşah Karadayı, Zeynep Baran Tatar, Berna Akdede, Tolga Binbay, Vesile Altınyazar, Halis Ulaş, Berna Yalınçetin, Güvem Gümüş-Akay, Burçin Cihan, Haldun Soygür, Eylem Şahin Cankurtaran, Semra Ulusoy Kaymak, Bart P F Rutten, Jim van Os
BACKGROUND: The relationship between childhood trauma (CT) and psychotic symptoms in patients with schizophrenia (SCZ), and subthreshold psychotic experiences in non-clinical populations is well-established. However, little is known about the relationship between subtypes of trauma and specific symptoms in patients, their siblings, and controls. It is also not clear which variables mediate the relationship between trauma and psychotic symptoms. METHODS: Seven hundred and forty-two patients with SCZ, 718 of their unaffected siblings and 1039 controls from three EU-GEI sites were assessed for CT, symptom severity, and cognitive schemas about self/others...
April 12, 2024: Psychological Medicine