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https://www.readbyqxmd.com/read/29053646/periapical-implant-lesion-a-systematic-review
#1
J-A Blaya-Tárraga, J Cervera-Ballester, D Peñarrocha-Oltra, M Peñarrocha-Diago
PURPOSE: The aim of this study was to systematically review the evidence for periapical implant lesion, which makes a patient more susceptible to the periapical lesion, frequency, symptoms, signs (including radiological findings) and possible treatment options. MATERIAL AND METHODS: A systematic literature review and analysis of publications included in PubMed, Embase and Cochrane; articles published until March 2016; with a populations, exposures and outcomes (PEO) search strategy was performed, focused on the issue: "In patients with periapical lesion to the implant during the osseointegration, what symptoms, signs, and changes in complementary examination manifested, for according to that stage, be intervened with the appropriate approach?"...
October 20, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29053491/safety-and-feasibility-of-early-physical-therapy-for-patients-on-extracorporeal-membrane-oxygenator-university-of-maryland-medical-center-experience
#2
Chris L Wells, Jenny Forrester, Joshua Vogel, Raymond Rector, Ali Tabatabai, Daniel Herr
OBJECTIVES: To examine the feasibility and safety of mobilizing patients while on extracorporeal membranous oxygenation support. DESIGN: Retrospective cohort study. SETTING: Medical and Surgical ICUs in a large tertiary care hospital in the United States. PATIENTS: Adults supported on extracorporeal membranous oxygenation from January 2014 to December 2015. MEASUREMENTS AND MAIN RESULTS: We reviewed the medical records from physical therapy, perfusion, and intensivists to obtain the number and type of physical therapy interventions and discharge status; extracorporeal membranous oxygenation type and description of support, cannulation sites; and risk management details of adverse effects, if any...
October 19, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29053121/-possibilities-of-cavinton-therapy-regimen-for-infusions-and-cavinton-comforte-in-acute-and-early-recovery-periods-after-ischemic-stroke
#3
L A Belova, V V Mashin, A N Proshin, A N Ovsyannicova, B B Kostishko
AIM: To study the efficacy of a current regimen of treatment with cavinton for infusions and cavinton comforte in patients with ischemic stroke in acute and early recovery periods and to evaluate an impact of treatment on erythrocyte deformity using atomic power microscopy. MATERIAL AND METHODS: One hundred and sixty-four patients with hemispheric ischemic stroke, aged from 30 to 79 years, were randomized into main (n=100) and control (n=64) groups. Patients of the main group received complex treatment (basic therapy and cavinton R for drop infusions (10 intravenously during 10 days) followed by cavinton R comforte in dose 10 mg, 1 tablet 3 times a day during 90 days)...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29052954/enlarged-perivascular-spaces-are-associated-with-health-related-quality-of-life-in-patients-with-acute-ischemic-stroke
#4
Yan Liang, Min Deng, Yang-Kun Chen, Vincent Mok, De-Feng Wang, Gabor S Ungvari, Chiu-Wing Winnie Chu, Eivind Berge, Wai-Kwong Tang
AIMS: This study explored the association between enlarged perivascular spaces (EPVS) and the health-related quality of life (HRQoL) in patients with acute ischemic stroke. METHODS: This was an observational study of consecutively screened patients with acute ischemic stroke from March 2010 to March 2015. EPVS were rated in the basal ganglia and the centrum semiovale with a validated scale. The HRQoL was assessed 3 months after the stroke onset using the Stroke-Specific Quality of Life (SSQoL)...
October 20, 2017: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/29051137/alzheimer-s-disease-in-social-media-content-analysis-of-youtube-videos
#5
Weizhou Tang, Kate Olscamp, Seul Ki Choi, Daniela B Friedman
BACKGROUND: Approximately 5.5 million Americans are living with Alzheimer's disease (AD) in 2017. YouTube is a popular platform for disseminating health information; however, little is known about messages specifically regarding AD that are being communicated through YouTube. OBJECTIVE: This study aims to examine video characteristics, content, speaker characteristics, and mobilizing information (cues to action) of YouTube videos focused on AD. METHODS: Videos uploaded to YouTube from 2013 to 2015 were searched with the term "Alzheimer's disease" on April 30th, 2016...
October 19, 2017: Interactive Journal of Medical Research
https://www.readbyqxmd.com/read/29050687/comparison-of-adverse-events-and-postoperative-mobilization-following-knee-extensor-mechanism-rupture-repair-a-systematic-review-and-network-meta-analysis
#6
Joseph Serino, Amin Mohamadi, Sebastian Orman, Brian McCormick, Philip Hanna, Michael J Weaver, Mitchel B Harris, Ara Nazarian, Arvind von Keudell
BACKGROUND: Extensor mechanism rupture (EMR) of the knee is a rare but potentially debilitating injury that often occurs due to trauma. While a wide variety of surgical treatments have been reported, there is currently no consensus on the most successful treatment method. The timing of post-operative joint mobilization is also critical for successful recovery after EMR repair. Despite the traditional method of complete immobilization for 6 weeks, there is an increasing trend towards early post-operative knee mobilization...
October 16, 2017: Injury
https://www.readbyqxmd.com/read/29049202/mandibular-gorham-stout-disease-a-case-report-and-literature-review
#7
Min Liu, Weiwei Liu, Chunyan Qiao, Bing Han
RATIONALE: Gorham-Stout disease (GSD) is characterized by aggressive bone resorption, proliferation of vascular or lymphatic vessels, and soft-tissue swelling. Bones that initially appear normal start to resorb, partially or completely. However, the etiology of GSD is unknown. PATIENT CONCERNS: A 29-year-old man with a chief complaint of toothache and mobility in the lower right mandible for the previous 1 year. DIAGNOSES: Gorham-Stout disease (GSD)...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29046768/smartphones-and-e-tablets-in-perioperative-medicine
#8
REVIEW
Frederic Michard
Smartphones and electronic tablets (e-tablets) have become ubiquitous devices. Their ease of use, smartness, accessibility, mobility and connectivity create unique opportunities to improve quality of surgical care from prehabilitation to rehabilitation. Before surgery, digital applications (Apps), serious games and text messaging may help for a better control of risk factors (hypertension, overweight), for smoking cessation, and for optimizing adherence to preoperative recommendations (e.g., regarding anticoagulation or antihypertensive treatments)...
October 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/29046269/what-clinical-information-is-valuable-to-doctors-using-mobile-electronic-medical-records-and-when
#9
Junetae Kim, Yura Lee, Sanghee Lim, Jeong Hoon Kim, Byungtae Lee, Jae-Ho Lee
BACKGROUND: There has been a lack of understanding on what types of specific clinical information are most valuable for doctors to access through mobile-based electronic medical records (m-EMRs) and when they access such information. Furthermore, it has not been clearly discussed why the value of such information is high. OBJECTIVE: The goal of this study was to investigate the types of clinical information that are most valuable to doctors to access through an m-EMR and when such information is accessed...
October 18, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29043890/-yeah-i-ve-grown-i-can-t-go-out-anymore-differences-in-perceived-risks-between-girls-and-boys-entering-adolescence
#10
Kristin Mmari, Caroline Moreau, Susannah Emily Gibbs, Sara De Meyer, Kristien Michielsen, Caroline W Kabiru, Bamidele Bello, Adesegun Fatusi, Chaohua Lou, Xiayun Zuo, Chunyan Yu, Ghada S T Al-Attar, Omaima El-Gibaly
This analysis is based on data from the Global Early Adolescent Study, which aims to understand the factors that predispose young people aged 10-14 years to positive or negative health trajectories. Specifically, interview transcripts from 202 adolescents and 191 parents across six diverse urban sites (Baltimore, Ghent, Nairobi, Ile Ife, Assuit and Shanghai) were analysed to compare the perceived risks associated with entering adolescence and how these risks differed by gender. Findings reveal that in all sites except Ghent, both young people and their parents perceived that girls face greater risks related to their sexual and reproductive health, and because of their sexual development, were perceived to require more protection...
October 18, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/29043459/mobility-of-pb-zn-cu-and-as-in-disturbed-forest-soils-affected-by-acid-rain
#11
Yulia V Kochergina, Martin Udatný, Vít Penížek, Martin Mihaljevič
Early efforts at remediation of contaminated soils involve overturn or removal of the uppermost soil horizons. We find that such disruption is counterproductive, as it actually increases the mobility of the heavy metals involved. In our study, we sought to replicate in a controlled manner this commonly used remediation strategy and measure Pb, Zn, Cu and As concentrations in all soil horizons-both prior to and 1 year after disruption by trenching. BCR analyses (sequential leaching) indicate that Pb is affected to the greatest degree and is most highly mobile; however, Zn and As remain insoluble, thus partially ameliorating the detrimental effect...
October 18, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29042342/reduction-in-fall-rate-in-dementia-managed-care-through-video-incident-review-pilot-study
#12
Eleonore Bayen, Julien Jacquemot, George Netscher, Pulkit Agrawal, Lynn Tabb Noyce, Alexandre Bayen
BACKGROUND: Falls of individuals with dementia are frequent, dangerous, and costly. Early detection and access to the history of a fall is crucial for efficient care and secondary prevention in cognitively impaired individuals. However, most falls remain unwitnessed events. Furthermore, understanding why and how a fall occurred is a challenge. Video capture and secure transmission of real-world falls thus stands as a promising assistive tool. OBJECTIVE: The objective of this study was to analyze how continuous video monitoring and review of falls of individuals with dementia can support better quality of care...
October 17, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29041916/early-coordinated-rehabilitation-in-acute-phase-after-hip-fracture-a-model-for-increased-patient-participation
#13
Gillian Asplin, Gunnel Carlsson, Lena Zidén, Gunilla Kjellby-Wendt
BACKGROUND: Studies have shown that patients with hip fracture treated in a Comprehensive Geriatric Care (CGC) unit report better results in comparison to orthopaedic care. Furthermore, involving patients in their healthcare by encouraging patient participation can result in better quality of care and improved outcomes. To our knowledge no study has been performed comparing rehabilitation programmes within a CGC unit during the acute phase after hip fracture with focus on improving patients' perceived participation and subsequent effect on patients' function...
October 17, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29040870/parkin-absence-accelerates-microtubule-aging-in-dopaminergic-neurons
#14
Daniele Cartelli, Alida Amadeo, Alessandra Maria Calogero, Francesca Vittoria Marialuisa Casagrande, Carmelita De Gregorio, Mariarosa Gioria, Naoko Kuzumaki, Ilaria Costa, Jenny Sassone, Andrea Ciammola, Nobutaka Hattori, Hideyuki Okano, Stefano Goldwurm, Laurent Roybon, Gianni Pezzoli, Graziella Cappelletti
Loss-of-function caused by mutations in the parkin gene (PARK2) lead to early-onset familial Parkinson's disease. Recently, mechanistic studies proved the ability of parkin in regulating mitochondria homeostasis and microtubule (MT) stability. Looking at these systems during aging of PARK2 knockout mice, we found that loss of parkin induced an accelerated (over)acetylation of MT system both in dopaminergic neuron cell bodies and fibers, localized in the substantia nigra and corpus striatum, respectively. Interestingly, in PARK2 knockout mice, changes of MT stability preceded the alteration of mitochondria transport...
September 20, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/29040840/experiences-of-structural-vulnerability-among-exotic-dancers-in-baltimore-maryland-co-occurring-social-and-economic-antecedents-of-hiv-sti-risk
#15
Meredith L Brantley, Katherine H A Footer, Sahnah Lim, Deanna Kerrigan, Susan G Sherman
BACKGROUND: Women who grow up in economic scarcity often face limited opportunities for upward mobility, as a result of challenges securing stable housing, quality education, and steady employment. Chronic instability may limit the capacity of women to protect themselves against HIV/STI-related harm when engaging in sexual activity or drug use. Characterizing the structural contexts that facilitate HIV/STI risk among women are critical to effective design and implementation of drug and sexual harm reduction interventions...
October 14, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29038897/-acute-achilles-tendon-rupture-state-of-the-art
#16
REVIEW
M Braunstein, S F Baumbach, V Herterich, W Böcker, H Polzer
The most favorable treatment for acute Achilles tendon ruptures remains controversial. In particular, three key questions are intensively debated: is operative or non-operative treatment superior? If surgery is performed, should open or minimally invasive percutaneous techniques be used? How should the follow-up treatment be carried out? The aim of this article is to answer these essential questions based on the currently available evidence. Non-operative treatment leads to a higher rate of re-ruptures and inferior functional results when compared to operative treatment...
October 16, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/29038868/the-global-spine-care-initiative-a-review-of-reviews-and-recommendations-for-the-non-invasive-management-of-acute-osteoporotic-vertebral-compression-fracture-pain-in-low-and-middle-income-communities
#17
REVIEW
Arthur Ameis, Kristi Randhawa, Hainan Yu, Pierre Côté, Scott Haldeman, Roger Chou, Eric L Hurwitz, Margareta Nordin, Jessica J Wong, Heather M Shearer, Anne Taylor-Vaisey
PURPOSE: The purpose of this review was to develop recommendations for non-invasive management of pain due to osteoporotic vertebral compression fractures (OVCF) that could be applied in medically underserved areas and low- and middle-income countries. METHODS: We conducted a systematic review and best evidence synthesis of systematic reviews on the non-invasive management of OVCF. Eligible reviews were critically appraised using the Scottish Intercollegiate Guidelines Network criteria...
October 16, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29036638/the-basic-tilted-helix-bundle-domain-of-the-prolyl-isomerase-fkbp25-is-a-novel-double-stranded-rna-binding-module
#18
David Dilworth, Santosh K Upadhyay, Pierre Bonnafous, Amiirah Bibi Edoo, Sarah Bourbigot, Francy Pesek-Jardim, Geoff Gudavicius, Jason J Serpa, Evgeniy V Petrotchenko, Christoph H Borchers, Christopher J Nelson, Cameron D Mackereth
Prolyl isomerases are defined by a catalytic domain that facilitates the cis-trans interconversion of proline residues. In most cases, additional domains in these enzymes add important biological function, including recruitment to a set of protein substrates. Here, we report that the N-terminal basic tilted helix bundle (BTHB) domain of the human prolyl isomerase FKBP25 confers specific binding to double-stranded RNA (dsRNA). This binding is selective over DNA as well as single-stranded oligonucleotides. We find that FKBP25 RNA-association is required for its nucleolar localization and for the vast majority of its protein interactions, including those with 60S pre-ribosome and early ribosome biogenesis factors...
September 25, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29035737/rethinking-liquid-biopsy-microfluidic-assays-for-mobile-tumor-cells-in-human-body-fluids
#19
REVIEW
Kuang Hong Neoh, Ayon Ahmed Hassan, Anqi Chen, Yukun Sun, Peng Liu, Kai-Feng Xu, Alice S T Wong, Ray P S Han
Traditionally, liquid biopsy is a blood test involving the harvesting of tumor materials from peripheral blood. Tumor cells from non-blood body fluids have always been clinically available in cytological examinations but limited for use in differential diagnosis due to the low sensitivity of conventional cytopathology. With the recent significant progress in microfluidic and downstream molecular technologies, liquid biopsies have now evolved to include harvesting tumor cells and DNA fragments in all kinds of non-blood body fluids...
October 3, 2017: Biomaterials
https://www.readbyqxmd.com/read/29034688/end-of-life-characteristics-and-palliative-care-provision-for-patients-with-motor-neuron-disease
#20
Hon Wai Benjamin Cheng, Oi Man Iman Chan, Chun Hung Red Chan, Wan Hung Chan, Koon Sim Fung, Kar Yin Wong
Motor neuron disease (MND) is a neurodegenerative disease and manifested as progressive decline in physical, respiratory, swallowing and communication function, and ultimately death. Traditional model of care was fragmented and did not match with multifacet needs of patients and carers. Furthermore, there could be lack of integrated care at end of life for patients with MND in most lower- and middle-income countries or in places with inadequate palliative care (PC) coverage. In view of this, a special workgroup for patients with MND, which includes neurologist, respiratory physician, rehabilitation specialist, and PC physician was formed in Hong Kong since year 2011...
January 1, 2017: American Journal of Hospice & Palliative Care
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