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https://www.readbyqxmd.com/read/29684712/high-salt-intake-enhances-swim-stress-induced-pvn-vasopressin-cell-activation-and-active-stress-coping
#1
N C Mitchell, T L Gilman, L C Daws, G M Toney
PURPOSE: Stress contributes to many psychiatric disorders; however, responsivity to stressors can vary depending on previous or current stress exposure. Relatively innocuous heterotypic (differing in type) stressors can summate to result in exaggerated neuronal and behavioral responses. Here we investigated the ability of prior high dietary sodium chloride (salt) intake, a dehydrating osmotic stressor, to enhance neuronal and behavioral responses of mice to an acute psychogenic swim stress (SS)...
April 6, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29684199/patterns-of-ses-health-disparities-among-older-adults-in-three-upper-middle-and-two-high-income-countries
#2
Mary McEniry, Rafael Samper-Ternent, Carmen Elisa Flórez, Renata Pardo, Carlos Cano-Gutierrez
Objectives: To examine the socioeconomic status (SES) health gradient for obesity, diabetes, and hypertension within a diverse group of health outcomes and behaviors among older adults (60+) in upper middle-income countries benchmarked with high-income countries. Method : We used data from three upper middle-income settings (Colombia-SABE-Bogotá, Mexico-SAGE, and South Africa-SAGE) and two high-income countries (England-ELSA and US-HRS) to estimate logistic regression models using age, gender, and education to predict health and health behaviors...
April 19, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29682709/-prevention-of-anastomotic-leakage-after-robotic-surgery-for-rectal-cancer
#3
Xiaohui Du, Xiaowei Xing
With popularity of robotic surgery system, robotic rectal cancer surgery is increasing. Precautionary measures of different perioperative periods should be taken to reduce the risk for anastomotic leakage. First, the general condition of patients should be acquainted and improved, and the risk for anastomotic leakage should be evaluated preoperatively. Preoperative neoadjuvant chemoradiotherapy may not increase the risk for anastomotic leakage after rectal surgery. The impact of routine bowel preparation to prevent anastomotic leakage needs to be verified further...
2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29681432/a-systematic-review-evaluating-the-role-of-nurses-and-processes-for-delivering-early-mobility-interventions-in-the-intensive-care-unit
#4
REVIEW
Anna Krupp, Linsey Steege, Barbara King
OBJECTIVES: To investigate processes for delivering early mobility interventions in adult intensive care unit patients used in research and quality improvement studies and the role of nurses in early mobility interventions. METHODS: A systematic review was conducted. Electronic databases PubMED, CINAHL, PEDro, and Cochrane were searched for studies published from 2000 to June 2017 that implemented an early mobility intervention in adult intensive care units. Included studies involved progression to ambulation as a component of the intervention, included the role of the nurse in preparing for or delivering the intervention, and reported at least one patient or organisational outcome measure...
April 19, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/29681047/the-effect-of-local-anesthetic-agent-infiltration-around-nephrostomy-tract-on-postoperative-pain-control-after-percutaneous-nephrolithotomy-a-single-centre-randomised-double-blind-placebocontrolled-clinical-trial
#5
Gokce Dundar, Kaan Gokcen, Gokhan Gokce, Emin Yener Gultekin
PURPOSE: Insufficient alleviation of pain after percutaneous nephrolithotomy causes patient dissatisfaction and generates additional morbidity factors by preventing early mobilization. This study investigated the effects of bupivacaine infiltration with two different doses around the nephrostomy tract after percutaneous nephrolithotomy. MATERIALS AND METHODS: Patients who underwent subcostal single entrance percutaneous nephrolithotomy were randomly divided into 3 groups of 20 patients...
April 22, 2018: Urology Journal
https://www.readbyqxmd.com/read/29680179/progress-in-understanding-the-pathophysiology-of-multiple-sclerosis
#6
REVIEW
H Zéphir
Multiple sclerosis (MS) arises in people who have a genetic susceptibility to environmental factors and events, which ultimately trigger the disease. It is thought that peripheral immune cells are mobilized and enter the CNS through the impaired blood-brain barrier in the subarachnoid space, as acute lesions show large numbers of macrophages and CD8+ T cells and, to a lesser extent, CD4+ T cells, B cells and plasma cells. Demyelination is mostly localized to focal lesions in early relapsing-remitting (RR) MS, whereas other areas of white matter appear normal...
April 18, 2018: Revue Neurologique
https://www.readbyqxmd.com/read/29680127/fungi-in-deep-subsurface-environments
#7
Magnus Ivarsson, Stefan Bengtson, Henrik Drake, Warren Francis
The igneous crust of the oceans and the continents represents the major part of Earth's lithosphere and has recently been recognized as a substantial, yet underexplored, microbial habitat. While prokaryotes have been the focus of most investigations, microeukaryotes have been surprisingly neglected. However, recent work acknowledges eukaryotes, and in particular fungi, as common inhabitants of the deep biosphere, including the deep igneous provinces. The fossil record of the subseafloor igneous crust, and to some extent the continental bedrock, establishes fungi or fungus-like organisms as inhabitants of deep rock since at least the Paleoproterozoic, which challenges the present notion of early fungal evolution...
2018: Advances in Applied Microbiology
https://www.readbyqxmd.com/read/29679256/biomechanical-features-of-six-design-of-the-delta-external-fixator-for-treating-pilon-fracture-a-finite-element-study
#8
Muhammad Hanif Ramlee, Mohd Ayub Sulong, Evelyn Garcia-Nieto, Daniel Angure Penaranda, Antonio Ros Felip, Mohammed Rafiq Abdul Kadir
Pilon fractures can be caused by high-energy vertical forces which may result in long-term patient immobilization. Many experts in orthopedic surgery recommend the use of a Delta external fixator for type III Pilon fracture treatment. This device can promote immediate healing of fractured bone, minimizing the rate of complications as well as allowing early mobilization. The characteristics of different types of the Delta frame have not been demonstrated yet. By using the finite element method, this study was conducted to determine the biomechanical characteristics of six different configurations (Model 1 until Model 6)...
April 21, 2018: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29678860/development-defects-of-hydroxy-fatty-acid-accumulating-seed-are-reduced-by-castor-acyltransferases
#9
Daniel Lunn, Gracen A Smith, James G Wallis, John Browse
Researchers have long endeavored to produce modified fatty acids in easily managed crop plants where they are not natively found. An important step toward this goal has been biosynthesis of these valuable products in model oilseeds. The successful production of such fatty acids has revealed barriers to broad application of this technology, including low seed oil and low proportion of the introduced fatty acid. An additional barrier, rarely examined in the literature, is reduced seed vigor. Here, we analyze the impact on seedling development of transgenic production of hydroxy-fatty acids...
April 20, 2018: Plant Physiology
https://www.readbyqxmd.com/read/29678650/femoseal%C3%A2-device-use-for-femoral-artery-closure-by-different-techniques
#10
Roberto Gabrielli, Maria Sofia Rosati, Massiliano Millarelli, Angelica Dante, Maurizio Maiorano, Aldo Musilli, Roberto Chiappa, Marco Ventura
BACKGROUND: Common femoral artery is still the most frequently site used for vascular access, mostly for peripheral arterial interventions and its puncture remains a significant source of patient's morbidity. Manual compression (MC) has been the gold standard for hemostasis after femoral catheterization until recently, but only in the last few years, vascular closure devices (VCDs) are replacing MC due to their rapid development. Nowadays also vascular surgeons are becoming familiar with VCDs...
April 17, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29678137/supporting-teams-to-optimize-function-and-independence-in-veterans-a-multi-study-program-and-mixed-methods-protocol
#11
Virginia Wang, Kelli Allen, Courtney H Van Houtven, Cynthia Coffman, Nina Sperber, Elizabeth P Mahanna, Cathleen Colón-Emeric, Helen Hoenig, George L Jackson, Teresa M Damush, Erika Price, Susan N Hastings
BACKGROUND: Successful implementation of new clinical programs depends on effectively establishing, reorganizing, or enhancing team structures and processes to coordinate the work of individuals who are interdependent in their tasks, manage relationships, and share responsibility for outcomes. However, a one-size-fits-all approach is rarely effective. In partnership with VA national clinical leaders and local clinical champions, the Optimizing Function and Independence VA Quality Enhancement Research Initiative program (Function QUERI) will evaluate efforts to implement team-based clinical programs for Veterans at risk for functional decline and disability...
April 20, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29678095/a-personalized-risk-stratification-platform-for-population-lifetime-healthcare
#12
Ali Daowd, Samina Raza Abidi, Ashraf Abusharekh, Syed Sibte Raza Abidi
Chronic diseases are the leading cause of death worldwide. It is well understood that if modifiable risk factors are targeted, most chronic diseases can be prevented. Lifetime health is an emerging health paradigm that aims to assist individuals to achieve desired health targets, and avoid harmful lifecycle choices to mitigate the risk of chronic diseases. Early risk identification is central to lifetime health. In this paper, we present a digital health-based platform (PRISM) that leverages artificial intelligence, data visualization and mobile health technologies to empower citizens to self-assess, self-monitor and self-manage their overall risk of major chronic diseases and pursue personalized chronic disease prevention programs...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29678068/a-mobile-early-stimulation-program-to-support-children-with-developmental-delays-in-brazil
#13
Raquel da Luz Dias, Kátia Cristina Correa Guimarães Silva, Marcela Raquel de Oliveira Lima, João Guilherme Bezerra Alves, Syed Sibte Raza Abidi
Developmental delay is a deviation development from the normative milestones during the childhood and it may be caused by neurological disorders. Early stimulation is a standardized and simple technique to treat developmental delays in children (aged 0-3 years), allowing them to reach the best development possible and to mitigate neuropsychomotor sequelae. However, the outcomes of the treatment depending on the involvement of the family, to continue the activities at home on a daily basis. To empower and educate parents of children with neurodevelopmental delays to administer standardized early stimulation programs at home, we developed a mobile early stimulation program that provides timely and evidence-based clinical decision support to health professionals and a personalized guidance to parents about how to administer early stimulation to their child at home...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29675419/a-cross-sectional-study-into-the-prevalence-of-dairy-cattle-lameness-and-associated-herd-level-risk-factors-in-england-and-wales
#14
Bethany E Griffiths, Dai Grove White, Georgios Oikonomou
Lameness is one of the most pressing issues within the dairy industry; it has severe economic implications while causing a serious impact on animal welfare. A study conducted approximately 10 years ago found the within farm lameness prevalence in the UK to be 36.8%. Our objective here is to provide an update on within farm lameness prevalence in the UK, and to provide further evidence on farm level risk factors. A convenience sample of 61 dairy farms were recruited across England and Wales from September 2015 to December 2016...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29674285/evaluation-of-muscle-strength-balance-and-functionality-of-individuals-with-type-2-charcot-marie-tooth-disease
#15
Iandra Maria Pinheiro de França Costa, Paula Santos Nunes, Eduardo Luis de Aquino Neves, Lidiane Carine Lima Santos Barreto, Catarina Andrade Garcez, Cynthia Coelho Souza, Paulo Márcio Pereira Oliveira, Luiz Augusto Sales Ferreira, Viviane Nascimento Brandão Lima, Adriano Antunes de Souza Araújo
BACKGROUND: Charcot-Marie-Tooth (CMT) disease is part of a group of genetically determined neuropathies. The intrinsic muscles of the feet and legs are affected early in the disease, impacting balance and mobility. RESEARCH QUESTION: The purpose of this study was to evaluate individuals with type 2 Charcot-Marie-Tooth disease to understand how motor changes interfere in balance and function. METHODS: The sample comprised 15 individuals with CMT2 from the same family (CMT2G) and a control group (CG) of healthy individuals matched for age and gender...
April 5, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29674140/impaired-ca-2-cycling-of-nonischemic-myocytes-contributes-to-sarcomere-dysfunction-early-after-myocardial-infarction
#16
Annette Kronenbitter, Florian Funk, Katarzyna Hackert, Simone Gorreßen, Dennis Glaser, Peter Boknik, Gereon Poschmann, Kai Stühler, Malgorzata Isić, Martina Krüger, Joachim P Schmitt
Changes in the nonischemic remote myocardium of the heart contribute to left ventricular dysfunction after ischemia and reperfusion (I/R). Understanding the underlying mechanisms early after I/R is crucial to improve the adaptation of the viable myocardium to increased mechanical demands. Here, we investigated the role of myocyte Ca2+ handling in the remote myocardium 24 h after 60 min LAD occlusion. Cardiomyocytes isolated from the basal noninfarct-related parts of wild type mouse hearts demonstrated depressed beat-to-beat Ca2+ handling...
April 16, 2018: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/29672187/early-life-medicaid-coverage-and-intergenerational-economic-mobility
#17
Rourke L O'Brien, Cassandra L Robertson
New data reveal significant variation in economic mobility outcomes across U.S. localities. This suggests that social structures, institutions, and public policies-particularly those that influence critical early-life environments-play an important role in shaping mobility processes. Using new county-level estimates of intergenerational economic mobility for children born between 1980 and 1986, we exploit the uneven expansions of Medicaid eligibility across states to isolate the causal effect of this specific policy change on mobility outcomes...
April 1, 2018: Journal of Health and Social Behavior
https://www.readbyqxmd.com/read/29671490/common-running-injuries-evaluation-and-management
#18
Michael J Arnold, Aaron L Moody
Running is a common form of exercise but predisposes athletes to several running-related injuries. Most running injuries are due to overuse and respond to conservative treatment. Tendinopathies in the patellar, Achilles, and hamstring tendons are common, and are primarily treated with eccentric exercise. Iliotibial band syndrome and patellofemoral pain syndrome are less common than patellar tendinopathy and are treated by strengthening exercises for the core and legs in addition to flexibility exercises. Acute hamstring strains and medial tibial stress syndrome require a period of relative rest, followed by stretching and graded return to activity...
April 15, 2018: American Family Physician
https://www.readbyqxmd.com/read/29670598/contribution-of-mobile-group-ii-introns-to-sinorhizobium-meliloti-genome-evolution
#19
REVIEW
Nicolás Toro, Francisco Martínez-Abarca, María D Molina-Sánchez, Fernando M García-Rodríguez, Rafael Nisa-Martínez
Mobile group II introns are ribozymes and retroelements that probably originate from bacteria. Sinorhizobium meliloti , the nitrogen-fixing endosymbiont of legumes of genus Medicago , harbors a large number of these retroelements. One of these elements, RmInt1, has been particularly successful at colonizing this multipartite genome. Many studies have improved our understanding of RmInt1 and phylogenetically related group II introns, their mobility mechanisms, spread and dynamics within S. meliloti and closely related species...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29670566/non-motor-symptoms-of-parkinson-s-disease-and-their-impact-on-quality-of-life-in-a-cohort-of-moroccan-patients
#20
Houyam Tibar, Khalil El Bayad, Ahmed Bouhouche, El Hachmia Ait Ben Haddou, Ali Benomar, Mohamed Yahyaoui, Abdelhamid Benazzouz, Wafa Regragui
Background: Non-motor symptoms (NMSs) are a real burden in Parkinson's disease (PD). They may appear in early pre-symptomatic stage as well as throughout the disease course. However, their relationship with the deterioration of the patient's quality of life (QoL) is still under debate. This study aimed to investigate the prevalence of NMSs and their impact on the QoL in a cohort of Moroccan patients. Methods: We carried out a cross-transactional study, where a total of 117 patients were submitted to a structured clinical interview and examination investigating motor and NMSs based on common and conventional scales...
2018: Frontiers in Neurology
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