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https://www.readbyqxmd.com/read/28642912/influence-of-10-sodium-ascorbate-gel-application-time-on-composite-bond-strength-to-bleached-enamel
#1
Cintia Gaio Murad, Suellen Nunes de Andrade, Lucio Ramos Disconzi, Eliseu Aldrighi Munchow, Evandro Piva, Renata Correa Pascotto, Sandra Kiss Moura
Objective To analyze bond strength to bleached enamel following application of 10% sodium ascorbate gel. Material and methods Forty third molars were allocated into five groups (n = 8): GP - unbleached specimens restored with composite resin; GN - specimens restored immediately after bleaching; and G15; G30 and G60 (test groups) - bleached specimens treated with 10% sodium ascorbate gel for 15, 30 and 60 min before restoration. The teeth were sectioned and the buccal and lingual faces were restored. After storage in distilled water (37 °C/24 h), sticks of ±0...
December 2016: Acta Biomaterialia Odontologica Scandinavica
https://www.readbyqxmd.com/read/28640745/the-amino-terminal-subdomain-of-glycoprotein-gc-of-schmallenberg-virus-disulfide-bonding-and-structural-determinants-of-neutralization
#2
Gleyder Roman-Sosa, Axel Karger, Franziska Kraatz, Andrea Aebischer, Kerstin Wernike, Pavlo Maksimov, Christopher H Lillig, Ilona Reimann, Emiliana Brocchi, Markus Keller, Martin Beer
Orthobunyaviruses are enveloped viruses that can cause human and animal diseases. A novel and major member is the Schmallenberg virus (SBV), the etiological agent of an emerging disease of ruminants that has been spreading all over Europe since 2011. The glycoproteins Gn and Gc of orthobunyaviruses mediate the viral entry, and specifically Gc is a major target for the humoral immune response. For example, the N terminal subdomain of the SBV glycoprotein Gc is targeted by neutralizing monoclonal antibodies that recognize conformational epitopes...
June 22, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28639628/multiple-socioeconomic-deprivation-and-impact-on-survival-in-patients-with-primary-glomerulonephritis
#3
Emily P McQuarrie, Bruce Mackinnon, Samira Bell, Stewart Fleming, Valerie McNeice, Graham Stewart, Jonathan G Fox, Colin C Geddes
Background: The impact of multiple socio-economic deprivation on patient outcomes in primary renal diseases is unknown. We aimed to assess whether risk of death or requiring renal replacement therapy (RRT) in patients with primary glomerulonephritis (GN) was higher in patients living in an area of multiple socio-economic deprivation. Methods: Patients undergoing native renal biopsy between 2000 and 2014 were identified. Baseline demographics, postcode at time of biopsy, follow-up blood pressure, proteinuria and time to death or RRT were recorded...
February 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28639555/ginkgo-biloba-and-lycopene-are-effective-on-cisplatin-induced-ototoxicity
#4
Erkan Esen, Fatih Özdoğan, Seren Gülşen Gürgen, Halil Erdem Özel, Serdar Başer, Selahattin Genç, Adin Selçuk
OBJECTIVE: The purpose of this study was to examine the anti-ototoxic impact of Ginkgo biloba extract and lycopene on the model of cisplatin-induced ototoxicity in rats. MATERIALS AND METHODS: Thirty-two Wistar albino rats were examined with the distortion product otoacoustic emission (DPOAE) test (MADSEN Capella2 ; GN Otometrics, ICS Medical, Chicago USA), and they were randomly divided into four groups. Group 1 (n=8) was defined as the healthy control group. Cisplatin was given intraperitoneally as single dose of 12 mg/kg to group 2 (n=8), group 3 (n=8), and group 4 (n=8)...
June 21, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28639531/outcome-of-bone-recycling-using-liquid-nitrogen-as-bone-reconstruction-procedure-in-malignant-and-recurrent-benign-aggressive-bone-tumour-of-distal-tibia-a-report-of-four-cases
#5
Eka Wiratnaya I Gede, Arrisna Artha Ida Ayu, Yudhi Setiawan I Gn, Wien Aryana Ign, Suyasa I Ketut, Siki Kawiyana I Ketut, Astawa Putu
Amputation still considered as primary choice of malignancy treatment in distal tibia. Bone recycling with liquid nitrogen for reconstruction following resection of malignant bone tumours offers many advantages. We presented four patients with osteosarcoma, Ewing sarcoma, adamantinoma and recurrent giant cell tumour over distal tibia. All of the patients underwent wide excision and bone recycling using liquid nitrogen as bone reconstruction. The mean functional Musculoskeletal Tumor Society (MSTS) score was 75% with no infection and local recurrent...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28637912/parallel-evaluation-of-the-maldi-sepsityper-and-verigene-bc-gn-assays-for-rapid-identification-of-gram-negative-bacilli-from-positive-blood-cultures
#6
Miguel A Arroyo, Gerald A Denys
Rapid identification of microorganisms from positive blood cultures has improved clinical management and antimicrobial stewardship. The advent of the matrix-assisted laser desorption time-of-flight Mass Spectrometry (MALDI-TOF MS) has reduced the time to identification of cultured isolates and is now often the definitive method used in the clinical microbiology laboratory. The commercial in vitro diagnostic MALDI Sepsityper (Sepsityper) kit has the potential for standardization and clinical routine use for the rapid identification of a broad range of bacteria from positive blood cultures...
June 21, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28636461/genice-a-novel-framework-for-gene-network-inference-by-clustering-exhaustive-search-and-multivariate-analysis
#7
Ricardo de Souza Jacomini, David Correa Martins-Jr, Felipe Leno da Silva, Anna Helena Reali Costa
Gene network (GN) inference from temporal gene expression data is a crucial and challenging problem in systems biology. Expression data sets usually consist of dozens of temporal samples, while networks consist of thousands of genes, thus rendering many inference methods unfeasible in practice. To improve the scalability of GN inference methods, we propose a novel framework called GeNICE, based on probabilistic GNs; the main novelty is the introduction of a clustering procedure to group genes with related expression profiles and to provide an approximate solution with reduced computational complexity...
June 21, 2017: Journal of Computational Biology: a Journal of Computational Molecular Cell Biology
https://www.readbyqxmd.com/read/28631039/graft-nephrectomy-in-children
#8
Benedict L Phillips, Chris J Callaghan
Kidney transplantation is recognised as the gold standard treatment of end-stage renal disease in most children, with excellent graft survival rates. When graft failure occurs, renal transplant recipients (RTRs) have the option of removal of the transplant (graft nephrectomy [GN]), or leaving the failed transplant in situ. The aims of this review are to discuss the indications for GN, surgical techniques, outcomes after GN (including risks of allosensitisation and the impact on subsequent transplants), and the possible role of routine GN in the asymptomatic RTR with a failed renal allograft...
June 19, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28622922/cross-sectional-human-study-of-soft-tissue-chin-stc-thickness-in-adult-patients-in-relation-to-sex-facial-pattern-and-skeletal-class
#9
Yolanda Gomez, Natalia Zamora, Beatriz Tarazona, Carlos Bellot-Arcís, Vanessa Paredes-Gallardo
PURPOSE: The aim of this study was to study the relations between the soft tissue chin (STC) and sex, skeletal class, and facial pattern; and to describe the shape and behavior of the STC. METHODS: 385 non-growing patients were selected, 206 women and 179 men, with a mean age of 28.8 years (SD 4.2). Patients were divided into groups by skeletal class (class I, II or III) and facial pattern (brachyfacial, mesofacial or dolichofacial). STC thicknesses were measured at pogonion (Pg), soft pogonion (Pg'), gnathion (Gn), soft gnathion (Gn'), menton (Me) and soft menton (Me') in the CBCTs...
April 19, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28620081/re-examining-neutrophil-participation-in-gn
#10
Dawn J Caster, David W Powell, Irina Miralda, Richard A Ward, Kenneth R McLeish
Significant advances in understanding the pathogenesis of GN have occurred in recent decades. Among those advances is the finding that both innate and adaptive immune cells contribute to the development of GN. Neutrophils were recognized as key contributors in early animal models of GN, at a time when the prevailing view considered neutrophils to function as nonspecific effector cells that die quickly after performing antimicrobial functions. However, advances over the past two decades have shown that neutrophil functions are more complex and sophisticated...
June 15, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28611855/variables-to-predict-nephrological-disease-in-general-and-glomerulonephritis-in-particular-in-patients-with-microhematuria
#11
Carsten Paul Bramlage, Manuel Wallbach, David Ellenberger, Cornelia Deutsch, Joan Minguet, Katherine Helen Smith, Johanna Stock, Alina Goninski, Peter Bramlage, Michael Koziolek, Gerhard Anton Mueller
BACKGROUND: Microhematuria (MH) is a symptom frequently leading to uncertainty as to when a nephrology referral is appropriate. Because MH may be indicative of severe kidney disorders, prompt diagnosis and potential treatment initiation can be important. We aimed to identify further variables that point at a nephrological cause, in particular of glomerulonephritis (GN), when MH is diagnosed. METHODS: A retrospective analysis of data acquired from patients attending a nephrology office due to MH was performed...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28607627/retroperitoneal-ganglioneuroma-mimicking-a-kidney-tumor-case-report
#12
Agnieszka Dąbrowska-Thing, Wojciech Rogowski, Ryszard Pacho, Ewa Nawrocka-Laskus, Żaneta Nitek
BACKGROUND: Ganglioneuroma (GN) is a rare benign tumor arising from the neural crest cells. The reported incidence of GN is one per million population. As a primary retroperitoneal tumor, it constitutes only a small percentage of 0.72 to 1.6%. GN can arise de novo or as a result of maturation of a neuroblastoma either spontaneously or after chemotherapy. The most common location is the posterior paraspinal mediastinum, retroperitoneum, neck and adrenal gland. However, GN can potentially occur anywhere along the peripheral autonomic ganglion sites...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28603964/particle-size-influences-on-the-coating-microstructure-through-green-chromia-inclusion-in-plasma-electrolytic-oxidation
#13
Chen-Yu Liu, Dah-Shyang Tsai, Jian-Mao Wang, James T J Tsai, Chen-Chia Chou
In an effort to color the aluminum alloy surface green via plasma electrolytic oxidation (PEO), two alkaline solutions have been employed with particulate inclusions and sodium aluminate. Electrolyte I comprises a self-made chromia pigment with a mean particle size 69 nm, whereas electrolyte II contains a commercially available pigment, GN-M, with a larger particle size 351 nm. Both pigments are oxygen deficient Cr2O3-δ of corundum-type structure before coating, the oxidative environment of PEO converts them into stoichiometric Cr2O3...
June 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28583886/risk-factors-and-clinical-outcomes-for-carbapenem-resistant-gram-negative-late-onset-sepsis-in-a-neonatal-intensive-care-unit
#14
Islam Nour, Heba Elsayed Eldegla, Nehad Nasef, Basma Shouman, Hesham Abdel-Hady, Abd Elazeez Shabaan
BACKGROUND: Gram-negative (GN), carbapenem-resistant (CR), late-onset sepsis (LOS) is a serious threat in the Neonatal Intensive Care Unit (NICU). OBJECTIVE: To assess the prevalence of CR-GN-LOS in NICU patients and to identify the risk factors and outcomes associated with its acquisition. METHODS: Neonates with carbapenem-sensitive (CS)-GN-LOS were compared with those with CR-GN-LOS in a 2-year observational study. RESULTS: A total of 158 patients had GN-LOS; 100 infants had CS-GN-LOS and 58 infants had CR-GN-LOS...
June 2, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28578053/bactericidal-effect-of-266-to-279nm-wavelength-uvc-leds-for-inactivation-of-gram-positive-and-gram-negative-foodborne-pathogenic-bacteria-and-yeasts
#15
Do-Kyun Kim, Soo-Ji Kim, Dong-Hyun Kang
Recently, UVC-LED technology has been validated as an alternative to irradiation with conventional mercury UV lamps. In this study, we sought to determine primary factors affecting reduction trends shown in several microorganisms. Four major foodborne pathogens (Escherichia coli O157:H7, Salmonella spp. Listeria monocytogenes, Staphylococcus aureus) and spoilage yeasts (Saccharomyces pastorianus, Pichia membranaefaciens), important to the brewing industry, were inoculated onto selective and non-selective media in order to investigate reduction tendencies at 4 different peak wavelengths (266 to 279nm)...
July 2017: Food Research International
https://www.readbyqxmd.com/read/28577431/supramolecular-organization-of-nmda-receptors-and-the-postsynaptic-density
#16
REVIEW
René Aw Frank, Seth Gn Grant
The postsynaptic density (PSD) of all vertebrate species share a highly complex proteome with ∼1000 conserved proteins that function as sophisticated molecular computational devices. Here, we review recent studies showing that this complexity can be understood in terms of the supramolecular organization of proteins, which self-assemble within a hierarchy of different length scales, including complexes, supercomplexes and nanodomains. We highlight how genetic and biochemical approaches in mice are being used to uncover the native molecular architecture of the synapse, revealing hitherto unknown molecular structures, including highly selective mechanisms for specifying the assembly of NMDAR-MAGUK supercomplexes...
May 31, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/28574993/weigh-the-pros-and-cons-to-ovarian-reserve-before-stripping-ovarian-endometriomas-prior-to-ivf-icsi-a-meta-analysis
#17
Xin Tao, Lei Chen, Shuqi Ge, Lisi Cai
PURPOSE: To explore the effects of conservative surgery for endometriomas on ovarian responsiveness during assisted reproductive technology (ART) and provide reproductive and gynecological doctors with a more reliable reference program for the treatment of endometriomas. METHODS: A literature search was performed by searching the PubMed, Embase, Cochrane Library, Web of Science and Science Direct databases. Studies with inter- and intra-patient comparisons of ovarian responses and oocyte quality between operated and unoperated ovaries and that met the inclusion criteria were retrieved, and the data from the outcome measures were extracted and pooled for this meta-analysis...
2017: PloS One
https://www.readbyqxmd.com/read/28574246/gel-electrolytes-with-polyamidopyridine-dendron-modified-talc-for-dye-sensitized-solar-cells
#18
Marcos A Santana Andrade, Armi Tiihonen, Kati Miettunen, Peter Lund, Ana F Nogueira, Heloise O Pastore
Organic-inorganic hybrid layered materials are proposed as additives in a quasi-solid gel electrolyte for dye-sensitized solar cells. Talcs could provide a low-cost and environmentally friendly, as well as abundant, option as gelators. Here, talcs were prepared by functionalizing an organotalc with three polyamidopyridine dendron generations, PAMPy-talc-Gn (n = 1, 2 and 3). PAMPy dendrons grow parallel to the lamellae plane and form an organized structure by intermolecular interactions. In addition, polyiodide-dendron charge-transfer complexes were prepared onto the organotalc by adsorption of iodine...
June 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28573489/ultrasonic-evaluation-of-renal-cortex-arterial-area-enables-differentiation-between-hypertensive-and-glomerulonephritis-related-chronic-kidney-disease
#19
Arkadiusz Lubas, Grzegorz Kade, Robert Ryczek, Piotr Banasiak, Przemysław Dyrla, Katarzyna Szamotulska, Daniel Schneditz, Stanisław Niemczyk
PURPOSE: Identifying the primary etiology of cardio-renal syndrome in a timely manner remains an ongoing challenge in nephrology. We hypothesized that hypertensive kidney damage can be distinguished from chronic glomerulonephritis at an early stage of chronic kidney disease (CKD) using ultrasound (US) Doppler sonography. METHODS: Fifty-six males (age 54 ± 15, BMI 28.3 ± 3.5 kg/m(2)) with hypertension and stable CKD at stages 2-4 [38 with essential hypertension (HT-CKD); 18 with glomerulonephritis (GN-CKD)] were studied...
June 1, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28573371/frequency-of-familial-mediterranean-fever-mefv-gene-mutations-in-patients-with-biopsy-proven-primary-glomerulonephritis
#20
Can Huzmeli, Ferhan Candan, Gokhan Bagci, Demet Alaygut, Ali Yilmaz, Asim Gedikli, Binnur Bagci, Meryem Timucin, Ilhan Sezgin, Mansur Kayatas
Primary glomerulopathies are those disorders that affect glomerular structure, function, or both in the absence of a multisystem disorder. We aimed to evaluate the frequency of MEFV gene mutation to show possible coexistence of FMF in patients diagnosed with biopsy-proven primary glomerulonephritis (GN). A total of 64 patients with biopsy-proven primary GN were included in the study. MEFV gene mutations examined retrospectively. The mean age of patients was 39.6 ± 13.4 (range 18-69), 35 of patients were female and 29 of patients were male...
June 1, 2017: Clinical Rheumatology
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