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Infantile hemangioma

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https://www.readbyqxmd.com/read/29224766/reversible-profound-sensorineural-hearing-loss-due-to-propranolol-sensitive-hemangioma-in-an-infant-with-phace-syndrome
#1
John N Bangiyev, Richard Gurgel, Sheryll L Vanderhooft, J Fredrik Grimmer
PHACE syndrome is the association of large or segmental infantile hemangiomas of the face or scalp with abnormalities within the posterior fossa, arteries, cardiovascular system, and eyes. We present a case of reversible profound sensorineural hearing loss due to a cerebellopontine angle infantile hemangioma that was successfully treated with propranolol.
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29224039/state-of-the-art-lasers-and-light-treatments-for-vascular-lesions-from-red-faces-to-vascular-malformations
#2
Manuel Valdebran, Brent Martin, Kristen M Kelly
Notable milestones in the treatment of vascular lesions have been achieved over the past century. Many cutaneous vascular lesions can be successfully treated with lightbased devices. In this review, we will discuss the treatment of port-wine birthmarks, lymphatic malformations, infantile hemangiomas, rosacea, venous lakes, pyogenic granulomas, cherry angiomas, and angiofibromas using lasers, total reflection amplification of spontaneous emission of radiation, intense pulsed light, and photodynamic therapy. In addition, for several of these diagnoses, we will review medical therapies that can be combined with light-based devices to provide enhanced results...
December 2017: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29217069/infantile-hemangiomas-in-the-head-and-neck-region
#3
REVIEW
Denise M Adams, Kiersten W Ricci
Infantile hemangiomas (IHs) are benign vascular tumors of infancy most common in the region of the head and neck. Infantile hemangiomas are common; but they are extremely heterogeneous and cause a range of complications depending on their morphology, size, or location. Medical interventions for high-risk patients include topical and systemic therapies, including oral propranolol, which has revolutionized the management of IHs over the past recent years. In the following article, the authors aim to provide a review of the natural history, pathology, complications, syndromes, and medical management of infantile hemangioma...
February 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29217058/management-of-infantile-hemangiomas-of-the-airway
#4
REVIEW
David H Darrow
Infantile hemangiomas (IHs) of the airway are far less common than their cutaneous counterparts, and their symptoms mimic those of viral croup. As a result, by the time these lesions are diagnosed, they are often advanced and causing airway compromise. Fortunately, the evolution of propranolol as an effective and safe pharmacotherapy has simplified management of IH and reduced the likelihood of complications previously seen with steroid therapy and surgery. Nevertheless, the otolaryngologist must be prepared with an alternate plan to manage lesions refractory to pharmacotherapy...
February 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29217057/the-surgical-management-of-infantile-hemangiomas
#5
REVIEW
Milton Waner
The surgical management of facial infantile hemangiomas presents a unique challenge. The aim of the surgeon should be to remove the hemangioma and to restore normal facial features. Each of the facial zones has its own special features and challenges. The surgeon should remember that the child started out with normal anatomy and that as the hemangioma proliferated, it displaced and thinned these normal structures and in many cases, expanded adjacent tissue. Hemangiomas do not as a rule, invade adjacent tissues as they proliferate...
February 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29217056/the-role-of-surgery-in-the-management-of-infantile-hemangiomas-what-is-the-best-timing
#6
REVIEW
Marcelo Hochman
Surgery for the management of infantile hemangiomas has become commonplace. Surgical technique articles are plentiful; however, little has been written about the timing of surgery. Knowledge of the biology of the tumors, data from developmental psychology, and the utility of facial reconstruction provide guidelines for timing of surgical intervention.
February 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29217038/corrigendum-to-glucose-transporter-isoform-1-receptor-positive-infantile-capillary-hemangiomas-case-report-and-literature-review-canadian-journal-of-ophthalmology-volume-49-2014-e156-e158
#7
Ashley Brissette, Y N Strube, James Farmer, Vladimir Kratky
No abstract text is available yet for this article.
December 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29193649/infantile-hemangioma-pathogenesis-and-mechanisms-of-action-of-propranolol
#8
REVIEW
Anita Rotter, Zilda Najjar Prado de Oliveira
Infantile hemangioma (IH) is the most common benign tumor of childhood, with a prevalence of 4 % to 10 %. It is characterized by a proliferative rapid growth phase, which starts after a few weeks of life, followed by a slow regression phase. In IH cases that are potentially disfiguring or life-threatening (10 % to 15 % of all cases), systemic therapy should be promptly initiated. Data source The present study reviews published scientific articles available in reliable electronic databases. Selected were all studies that evaluated the pathogenesis of IH and the mechanisms of action of propranolol...
November 28, 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29192323/significant-inhibition-of-infantile-hemangioma-growth-by-sustained-delivery-of-urea-from-liposomes-in-microspheres
#9
Xiaoshuang Zhu, Xiaonan Guo, Dakan Liu, Yubin Gong, Jin Sun, Changxian Dong
Infantile hemangioma (IH) is a benign pediatric tumor, and rapid growth of IH can result in serious morbidity and even mortality. Only one drug Hemangeol™ (propranolol hydrochloride oral solution) has been approved for the treatment of IH, whereas patients suffer from its adverse effects and high frequency of administration. We have used urea, an organic compound and a normal body metabolite, in the treatment of IH for 20 years, and demonstrated that urea is an effective and well-tolerated treatment for IH...
January 2018: Oncology Reports
https://www.readbyqxmd.com/read/29185949/atypical-presentation-of-infantile-hepatic-hemangioma-a-case-study
#10
Ashley Sartori, Gayle Leary Omansky, Steven Ringer
Infantile hepatic hemangioma (IHH) is the most common benign hepatic tumor of infancy. It is characterized by rapid proliferation in the first year of life, followed by slow involution during childhood. Presentation can range from asymptomatic to severe, high-output congestive heart failure (CHF). The purpose of this article is to review the case of an infant with an atypical presentation of IHH. It also addresses pathophysiology, diagnosis, management, and multidisciplinary team care.
November 1, 2017: Neonatal Network: NN
https://www.readbyqxmd.com/read/29159525/hepatic-tumors-of-vascular-origin-imaging-appearances
#11
Eric C Ehman, Michael S Torbenson, Michael L Wells, Brian T Welch, Scott M Thompson, Ishan Garg, Sudhakar K Venkatesh
A number of benign and malignant neoplasms may arise from the vascular elements within the liver parenchyma. Lesions discussed in this article include angiosarcoma, epithelioid hemangioendothelioma, solitary fibrous tumor (hemangiopericytoma), infantile, and cavernous hemangiomas. Despite a common theme of vascular origin, the pathologic and imaging appearance of these entities can be heterogeneous. Angiosarcomas are bizarrely enhancing, highly aggressive tumors, which often present with metastatic disease...
November 20, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29151787/infantile-hemangiomas-a-7-year-experience-of-a-single-center
#12
Mădălina Bota, Gheorghe Popa, Cristina Lucia Blag, Daniel-Corneliu Leucuta, Alexandru Tătaru
Objectives: The aim of the study was to describe the historical and clinical characteristics of hemangiomas in a series of cases of our clinic. Methods: This is a retrospective study of 36 patients with infantile hemangiomas consulted in our clinic. Results: We had 14 multiple hemangiomas, and 1 kaposiform hemangioendothelioma. Almost two-thirds involved the cephalic extremity, and 76% of the cases were treated. Pregnancy risk factors included prematurity, low-birth weight and respiratory distress syndrome...
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29149854/cardiac-arrest-in-a-toddler-treated-with-propranolol-for-infantile-hemangioma-a-case-report
#13
Alvise Tosoni, Mario Cutrone, Maurizio Dalle Carbonare, Andrea Pettenazzo, Giorgio Perilongo, Stefano Sartori
BACKGROUND: Propranolol has become the first-line treatment for complicated Infantile Hemangioma (IH), showing so far a good risk-benefit profile. CASE PRESENTATION: We report the case of a toddler, on propranolol, who suffered cardiac arrest during an acute viral infection. She had a neurally-mediated syncope that progressed to asystole, probably because of concurrent factors as dehydration, beta-blocking and probably individual susceptibility to vaso-vagal phenomena...
November 17, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29147770/-infantile-hemangioma-of-the-eyelid
#14
F Lang, U P Press
Hemangiomas are one of the most common vascular tumors in infancy. In most cases no therapy is necessary and spontaneous regression is observed; however, if they arise in the periocular region, immediate action is required as rapid growth frequently leads to obstruction of the visual field with the risk of developing amblyopia and orbital suppression up to permanent disfigurement and stigmatization of those affected. Novel pharmaceutical treatment options led to a significant paradigm shift in the treatment of pediatric hemangiomas...
November 16, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29145889/quality-of-life-in-children-with-infantile-hemangioma-a-case-control-study
#15
Chuan Wang, Yanan Li, Bo Xiang, Fei Xiong, Kai Li, Kaiying Yang, Siyuan Chen, Yi Ji
BACKGROUND: Infantile hemangioma (IH) is the most common vascular tumor in children. It is controversial whether IHs has effects on the quality of life (QOL) in patients of whom IH poses no threat or potential for complication. Thus, we conducted this study to evaluate the q QOL in patients with IH and find the predictors of poor QOL. METHODS: The PedsQL 4.0 Genetic Core Scales and the PedsQL family information form were administered to parents of children with IH and healthy children both younger than 2-year-old...
November 16, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29144051/infantile-hemangiomas-with-conjunctival-involvement-an%C3%A2-underreported-occurrence
#16
Martin Theiler, Eulalia Baselga, Christina Gerth-Kahlert, Erin F Mathes, Agnes Schwieger-Briel, Karla Chaloupka, Lisa Weibel, Ilona J Frieden
BACKGROUND/OBJECTIVES: Infantile hemangiomas (IHs) involving the conjunctiva are only anecdotally reported in the literature and little is known about their clinical course. In a retrospective case series we aimed to better delineate the clinical presentation, complications, and response to treatment of this uncommon subtype of IH. A classification of conjunctival IH is proposed. METHODS: Medical charts at three academic pediatric dermatology institutions were retrospectively analyzed...
November 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29136059/concurrent-sturge-weber-syndrome-facial-infantile-hemangioma-and-cutis-marmorata-telangiectatica-congenita
#17
Nina Poliak, Anthony Rainey
We present a unique case of 3 vascular malformations-Sturge-Weber syndrome (SWS), facial infantile hemangioma (IH), and cutis marmorata telangiectatica congenita (CMTC)-with dermatologic manifestations presenting in the same patient. This case highlights the possibility of occurrence of multiple vascular malformations in the same patient; the potential role of epigenetic factors; and the importance of a multidisciplinary approach to diagnose, treat, and manage this complicated interplay of vascular abnormalities to achieve the best outcome...
October 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29126563/-giant-infantile-hemangioma-of-the-eyelid
#18
T Abdellaoui, N Laaribi, R Zerrouk, F Elasri, K Reda, A Oubaaz
No abstract text is available yet for this article.
November 7, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29113884/orbital-infantile-hemangioma-and-rhabdomyosarcoma-in-children-differentiation-using-diffusion-weighted-magnetic-resonance-imaging
#19
Stephen F Kralik, Kathryn M Haider, Remy R Lobo, Nucharin Supakul, Sonia F Calloni, Bruno P Soares
PURPOSE: To evaluate differences in magnetic resonance imaging (MRI) appearance between infantile hemangiomas and rhabdomyosarcomas of the orbit in pediatric patients using diffusion-weighted imaging. METHODS: A multicenter retrospective review of MRIs of pediatric patients with infantile hemangiomas and rhabdomyosarcomas of the orbit was performed. MRI examinations from a total of 21 patients with infantile hemangiomas and 12 patients with rhabdomyosarcomas of the orbit were independently reviewed by two subspecialty board-certified neuroradiologists masked to the diagnosis...
November 4, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29113263/artesunate-inhibits-proliferation-and-invasion-of-mouse-hemangioendothelioma-cells-in-vitro-and-of-tumor-growth-in-vivo
#20
Ning Wang, Hongxia Chen, Yinping Teng, Xionghui Ding, Huan Wu, Xianqing Jin
Artesunate has been demonstrated to be a novel potential antitumor agent in numerous studies. However, its efficacy in infantile hemangioma is unknown. The aim of the present study was to investigate the role of artesunate in the control of vascular tumor biological behavior and molecular mechanism using mouse hemangioendothelioma endothelial (EOMA) cells and a nude mouse model. Cell viability, apoptosis and invasion were determined by an MTT assay, flow cytometric analysis and Transwell invasion assay, respectively...
November 2017: Oncology Letters
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