keyword
MENU ▼
Read by QxMD icon Read
search

Basal cell carcinoma, Squamous cell carcinoma

keyword
https://www.readbyqxmd.com/read/28640761/commentary-on-development-of-basal-cell-carcinoma-with-squamous-differentiation-during-vismodegib-treatment
#1
Anne Lynn S Chang
No abstract text is available yet for this article.
July 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28639581/a-unique-lesion-of-the-esophageal-mucosal-epithelium-low-grade-intraepithelial-neoplasia-or-basal-layer-type-squamous-cell-carcinoma
#2
Yan Zhao, Yi-Wei Fu, Qi Sun
No abstract text is available yet for this article.
July 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28638810/common-malignant-cutaneous-conditions-among-albinos-in-kenya
#3
Seyed Emad Emadi, Andrew Juma Suleh, Farhang Babamahmoodi, Fatemeh Ahangarkani, Vanessa Betty Chelimo, Beatrice Mutai, Seyyed Reza Raeeskarami, Alireza Ghanadan, Seyed Naser Emadi
Background: Albinos in Africa are at constant risk of developing skin cancer due to the damage caused by ultra-violet exposure. This study identifies the common skin conditions among albinos in Kenya as a country located along the equator. Methods: In this descriptive study on albino patients who were admitted to Mbagathi District Hospital in Nairobi, Kenya the census method was used for sampling and a total of 151 albinos were registered. All necessary data including age, gender, type, site and the number of skin lesions were recorded...
2017: Medical Journal of the Islamic Republic of Iran
https://www.readbyqxmd.com/read/28633362/human-papillomavirus-related-oropharyngeal-cancer
#4
M Taberna, M Mena, M A Pavón, L Alemany, M L Gillison, R Mesía
High-risk (HR) human papillomavirus (HPV) is now recognised as the principal cause of the increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in some parts of the world.The primary risk factor for developing HPV-related OPSCC is oral HPV-infection and the majority of oral HPV-infections are acquired by oral sex. Progression into a OPSCC includes persistent infection with evasion of immune response in the microenvironment, the activation of viral early genes (E6, E7) in basal epithelial cells, the deregulation of cell cycle and the accumulation of chromosomal instability...
June 15, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28622414/reflectance-confocal-microscopic-presentation-of-basosquamous-carcinoma
#5
A Oliveira, I Zalaudek
Basosquamous carcinoma (BSC) is considered a variant of basal cell carcinoma (BCC) associated with squamous differentiation.(1) It may display local aggressive behavior, and increased potential for recurrence and metastases.(2) Therefore, early and appropriate treatment will have prognostic repercussion. This article is protected by copyright. All rights reserved.
June 16, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28615224/risk-of-second-malignancies-in-solid-organ-transplant-recipients-who-develop-keratinocyte%C3%A2-cancers
#6
Rachel Zamoiski, Elizabeth L Yanik, Todd M Gibson, Elizabeth K Cahoon, Margaret M Madeleine, Charles F Lynch, Sally Gustafson, Marc T Goodman, Melissa Skeans, Ajay Israni, Eric A Engels, Lindsay M Morton
Solid organ transplant recipients have increased risk for developing keratinocyte cancers (KC), including cutaneous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), in part as a result of immunosuppressive medications administered to prevent graft rejection. In the general population, KC are associated with increased risks of subsequent malignancy, however, the risk in organ transplant populations has not been evaluated. We addressed this question by linking the U.S. Scientific Registry of Transplant Recipients, which includes data on KC occurrence, with 15 state cancer registries...
June 14, 2017: Cancer Research
https://www.readbyqxmd.com/read/28609551/chronic-exposure-to-tetracyclines-and-subsequent-diagnosis-for-non-melanoma-skin-cancer-in-a-large-midwestern-u-s-patient-population
#7
P P Vakharia, B Nardone, B J Schlosser, D Lee, L Serrano, D P West
Tetracyclines (TCNs) are commonly used in the management of several chronic dermatological disorders, partly due to their affinity for inflamed skin tissue, as they are known to suppress cytokines including tumor necrosis factor-alpha and interleukin-6 that are typically involved in inflammatory skin disorders.(1) TCNs are known to be photoreactive following ultraviolet (UV) radiation exposure, a known risk factor for the development of nonmelanoma skin cancer (NMSC), notably basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)...
June 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28609160/circulating-scca-igm-complex-is-a-useful-biomarker-to-predict-the-outcome-of-therapy-in-hepatocellular-carcinoma-patients
#8
Maria Guarino, Giovan G Di Costanzo, Andrea Gallotta, Raffaella Tortora, Laura Paneghetti, Francesco Auriemma, Concetta Tuccillo, Giorgio Fassina, Nicola Caporaso, Filomena Morisco
INTRODUCTION: Hepatocellular carcinoma (HCC) develops in about 3-4% of cirrhotic patients every year. The squamous cell carcinoma antigen (SCCA) has been found elevated in liver cancer specimens by immunohistochemistry, and detected in complex with IgM (SCCA-IgM) in the serum of patients with HCC. The aim of this study was to evaluate the ability of serological SCCA-IgM levels to predict the efficacy of HCC therapy. MATERIALS AND METHODS: From April 2012 to April 2014, 131 patients with a new diagnosis of HCC were enrolled...
June 13, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/28605380/establishment-of-a-clinic-based-biorepository
#9
Sarah E Belden, Chandana K Uppalapati, Agnes S Pascual, McKale R Montgomery, Kathryn J Leyva, Elizabeth E Hull, Richard L Averitte
The incidence of skin cancer (e.g., squamous cell carcinoma, basal cell carcinoma, and melanoma) has been increasing over the past several years. It is expected that there will be a parallel demand for cutaneous tumor samples for biomedical research studies. Tissue availability, however, is limited due the cost of establishing a biorepository and the lack of protocols available for obtaining clinical samples that do not interfere with clinical operations. A protocol was established to collect and process cutaneous tumor and associated blood and saliva samples that has minimal impact on routine clinical procedures on the date of a Mohs surgery...
May 29, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28598870/molecularly-targeted-agents-in-oculoplastic-surgery
#10
Richard C Allen
PURPOSE OF REVIEW: Significant advances have been made in oncology and rheumatology with the introduction of molecularly targeted agents (MTAs). MTAs consist of monoclonal antibodies and small molecule inhibitors. The purpose of this manuscript is to review the recent applications of MTAs to orbital, lacrimal, and eyelid disease. RECENT FINDINGS: The use of monoclonal antibodies has been described in the treatment of orbital vascular lesions, lymphoma, and squamous cell carcinoma...
June 8, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28596803/volumetric-arc-therapy-for-total-scalp-irradiation-case-report-for-a-recurrent-basal-cell-carcinoma-of-the-scalp
#11
Francisco Lozano, Naipy Perez, Alejandro Iglesias, Xiaodong Xu, Marco A Amendola, Michael Scott, Erich Companioni, Beatriz E Amendola
Total scalp irradiation may be used to treat numerous conditions including squamous and basal cell carcinomas. These conditions are relatively uncommon and patients are frequently treated with palliative intent. In this report, we describe a volumetric arc therapy technique using photon beams for curative intent in an 84 years old patient with recurrent basal cell carcinoma of the scalp. Dose was 50Gy (2Gy per session) to the planning target volume (PTV) followed by a 10 Gy boost to the macroscopic disease on the forehead...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28593937/basaloid-squamous-cell-carcinoma-of-the-head-and-neck-subclassification-into-basal-ductal-and-mixed-subtypes-based-on-comparison-of-clinico-pathologic-features-and-expression-of-p53-cyclin-d1-epidermal-growth-factor-receptor-p16-and-human-papillomavirus
#12
Kyung-Ja Cho, Se-Un Jeong, Sung Bae Kim, Sang-Wook Lee, Seung-Ho Choi, Soon Yuhl Nam, Sang Yoon Kim
Background: Basaloid squamous cell carcinoma (BSCC) is a rare variant of squamous cell carcinoma with distinct pathologic characteristics. The histogenesis of BSCC is not fully understood, and the cancer has been suggested to originate from a totipotent primitive cell in the basal cell layer of the surface epithelium or in the proximal duct of secretory glands. Materials and Methods: Twenty-six cases of head and neck BSCC from Asan Medical Center, Seoul, Korea, reported during a 14-year-period were subclassified into basal, ductal, and mixed subtypes according to the expression of basal (cytokeratin [CK] 5/6, p63) or ductal markers (CK7, CK8/18)...
June 8, 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/28591439/retrospective-evaluation-of-exposure-to-natural-uv-radiation-experiences-with-the-online-uv-history-tool-in-a-field-study
#13
Wobbeke Weistenhöfer, Julia Hiller, Hans Drexler, Johannes Kiesel
BACKGROUND: Cutaneous squamous cell carcinoma and multiple actinic keratoses can be recognized as occupational diseases if the site affected has been subjected to additional occupational UV exposure of at least 40 %. An online UV history tool that allows for the quantification of occupational and recreational UV doses was now tested in a field study. PATIENTS AND METHODS: Ninety-nine patients with nonmelanoma skin cancer were examined. Patient history with respect to UV exposure was obtained using the online UV history tool...
June 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28590951/cutaneous-squamous-cell-carcinoma-review-of-the-eighth-edition-of-the-american-joint-committee-on-cancer-staging-guidelines-prognostic-factors-and-histopathologic-variants
#14
Kiran Motaparthi, Jyoti P Kapil, Elsa F Velazquez
Cutaneous squamous cell carcinoma is the second most common form of nonmelanoma skin cancer after basal cell carcinoma and accounts for the majority of nonmelanoma skin cancer-related deaths. In 2017, the American Joint Committee on Cancer revised the staging guidelines of cutaneous squamous cell carcinoma to reflect recent evidence concerning high-risk clinicopathologic features. This update reviews the literature on prognostic features and staging, including the eighth edition of the American Joint Committee on Cancer Staging Manual...
July 2017: Advances in Anatomic Pathology
https://www.readbyqxmd.com/read/28589622/cutaneous-malignancies-simulating-seborrheic-keratoses-an-underappreciated-phenomenon
#15
Tiffany Y Chen, Annie O Morrison, Clay J Cockerell
BACKGROUND: Seborrheic keratosis (SK), a common and benign entity, is generally diagnosed clinically without the need for a biopsy. Given their variable appearance, SK may mimic cancer clinically and require biopsy for clinically equivocal cases. A clinician may also choose to perform biopsies on SK based on other circumstances, such as cosmetic reasons, or SK being in an inconvenient and irritative location. METHODS: Dermatopathology samples from 2015 obtained from private and university locations were retrospectively assessed...
June 7, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28584022/ikk%C3%AE-mediated-resistance-to-skin-cancer-development-is-ink4a-arf-dependent
#16
Angustias Page, Ana Bravo, Cristian Suárez-Cabrera, Josefa P Alameda, M LLanos Casanova, Corina Lorz, Carmen Segrelles, Jose C Segovia, Jesus M Paramio, Manuel Navarro, Angel Ramírez
IKKβ (encoded by IKBKB) is a protein kinase that regulates the activity of numerous proteins important in several signaling pathways, such as the nuclear factor kappa B (NF-κB) pathway. IKKβ exerts a pro-tumorigenic role in several animal models of lung, hepatic, intestinal and oral cancer. In addition, genomic and proteomic studies of human tumors also indicate that IKBKB gene is amplified or overexpressed in multiple tumor types. Here, the relevance of IKKβ in skin cancer was determined by performing carcinogenesis studies in animal models overexpressing IKKβ in the basal skin layer...
June 5, 2017: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/28578364/xeroderma-pigmentosum-at-a-tertiary-care-center-in-saudi-arabia
#17
Lenah Alwatban, Yousef Binamer
BACKGROUND: Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder caused by defective DNA repair that results in extreme sensitivity to ultraviolet (UV) rays. Depending on the type of XP, the disease may affect the skin, eyes and nervous system. OBJECTIVES: Describe the dermatologic manifestations in patients suffering from XP. DESIGN: Retrospective, descriptive review of medical records. SETTING: Dermatology clinic at tertiary care center in Riyadh...
May 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/28570726/cost-effectiveness-of-early-division-of-the-forehead-flap-pedicle
#18
Hollin E Calloway, Sami P Moubayed, Sam P Most
Importance: The paramedian forehead flap is considered the gold standard procedure to optimally reconstruct major defects of the nose, but this procedure generally requires 2 stages, where the flap pedicle is divided 3 weeks following the initial surgery to ensure adequate revascularization of the flap from the surrounding recipient tissue bed, which can cost a patient time out of work or away from normal social habits. It has previously been shown that the pedicle may be safely divided after 2 weeks in select patients where revascularization from the recipient bed was confirmed using intraoperative laser fluorescence angiography to potentially save the patient time and money...
June 1, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28561682/advances-in-the-treatment-of-advanced-extracutaneous-melanomas-and-nonmelanoma-skin-cancers
#19
Kimberly M Komatsubara, Joanne Jeter, Richard D Carvajal, Kim Margolin, Dirk Schadendorf, Axel Hauschild
Cutaneous malignancies make up the greatest proportion of all human cancers and include melanomas as well as nonmelanoma skin cancers (NMSCs) such as basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), as well as less common Merkel cell carcinoma (MCC), cutaneous lymphomas, cutaneous adnexal tumors, Kaposi sarcomas, and other sarcomas. Each of these NMSCs differ significantly in biology, clinical behavior, and optimal treatment recommendations from each other and from cutaneous melanoma...
2017: American Society of Clinical Oncology Educational Book
https://www.readbyqxmd.com/read/28556957/increased-frequency-of-bronchiolar-histotypes-in-lung-carcinomas-associated-with-idiopathic-pulmonary-fibrosis
#20
Anna Caliò, Veronica Lever, Andrea Rossi, Eliana Gilioli, Matteo Brunelli, Alessandra Dubini, Sara Tomassetti, Sara Piciucchi, Alessia Nottegar, Giulio Rossi, Marianne Kambouchner, Alessandra Cancellieri, Mattia Barbareschi, Giuseppe Pelosi, Claudio Doglioni, Alberto Cavazza, Rodolfo Carella, Paolo Graziano, Bruno Murer, Venerino Poletti, Marco Chilosi
AIMS: The association between lung cancer and idiopathic pulmonary fibrosis (IPF) is well-known, however the significance of this association is poorly understood. Bronchiolar honeycomb cysts have been proposed as possible precursors for development of carcinoma, but limited evidence of this hypothesis is available. METHODS AND RESULTS: Thirty-three lung carcinomas arising in patients with IPF have been analyzed using a panel of immunohistochemical markers. The antibodies included pneumocyte markers (TTF1, Napsin-A, SPA1), the goblet cell marker MUC5AC, markers of basal/squamous cell differentiation (CK5/6, ΔN-p63) and markers related to enteric differentiation (CDX2, MUC2, CK20, villin)...
May 30, 2017: Histopathology
keyword
keyword
45625
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"