Emanuele La Corte, Daniela Eldahaby, Elena Greco, Domenico Aquino, Giacomo Bertolini, Vincenzo Levi, Malte Ottenhausen, Greta Demichelis, Luigi Michele Romito, Francesco Acerbi, Morgan Broggi, Marco Paolo Schiariti, Paolo Ferroli, Maria Grazia Bruzzone, Graziano Serrao
The frontal aslant tract (FAT) is a recently identified white matter tract connecting the supplementary motor complex and lateral superior frontal gyrus to the inferior frontal gyrus. Advancements in neuroimaging and refinements to anatomical dissection techniques of the human brain white matter contributed to the recent description of the FAT anatomical and functional connectivity and its role in the pathogenesis of several neurological, psychiatric, and neurosurgical disorders. Through the application of diffusion tractography and intraoperative electrical brain stimulation, the FAT was shown to have a role in speech and language functions (verbal fluency, initiation and inhibition of speech, sentence production, and lexical decision), working memory, visual-motor activities, orofacial movements, social community tasks, attention, and music processing...
2021: Frontiers in Neurology