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https://www.readbyqxmd.com/read/29903519/transcatheter-or-surgical-treatment-of-severe-aortic-stenosis-and-coronary-artery-disease-a-comparative-analysis-from-the-italian-observant-study
#1
Marco Barbanti, Sergio Buccheri, Davide Capodanno, Paola D'Errigo, Marco Ranucci, Stefano Rosato, Gennaro Santoro, Danilo Fusco, Corrado Tamburino, Fausto Biancari, Fulvia Seccareccia
BACKGROUND: To assess clinical outcomes of patients with concomitant severe aortic stenosis (AS) and coronary artery disease (CAD) who underwent transcatheter aortic valve implantation (TAVI) and percutaneous coronary intervention (PCI) or surgical aortic valve replacement (SAVR) and coronary artery bypass grafting (CABG). METHODS: Data were extracted from the multicenter OBSERVANT study. For the purposes of the present analysis, we included only patients with established stable CAD meeting any of the following inclusion criteria: 1) TAVI patients with CAD undergoing staged PCI or TAVI and PCI in the same session; 2) SAVR patients undergoing combined SAVR and CABG in the same session...
June 7, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29903030/diastolic-dysfunction-is-common-and-predicts-outcome-after-cardiac-surgery
#2
Thomas S Metkus, Alejandro Suarez-Pierre, Todd C Crawford, Jennifer S Lawton, Lee Goeddel, Jeffrey Dodd-O, Monica Mukherjee, Theodore P Abraham, Glenn J Whitman
BACKGROUND: Diastolic dysfunction (DD) identified on echocardiography predicts mortality after cardiac surgery, however the most useful diastolic parameters for assessment and the association of DD with prolonged mechanical ventilation, ICU re-admission, and hospital length of stay are not established. METHODS: We included patients that underwent coronary artery bypass grafting (CABG), aortic valve replacement (AVR) or a combined procedure (CAB-AVR) from 2010 to 2016, and who had preoperative transthoracic echocardiography (TTE) at our institution within 6 months of the operation...
June 15, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29898676/improved-short-and-long-term-survival-associated-with-percutaneous-coronary-intervention-in-the-elderly-patients-with-acute-coronary-syndrome
#3
Xiaojing Chen, Salim Bary Barywani, Runa Sigurjonsdottir, Michael Fu
BACKGROUND: Percutaneous coronary intervention (PCI) are increasingly used in daily clinical practice in elderly patients with acute coronary syndrome (ACS) despite limited evidence. The purpose of this study was to assess the impact of PCI on short and long term survivals in a large cohort of elderly patients with ACS from a "real world". METHODS: We enrolled 491 patients aged ≥70 years admitted to our institution with ACS from 2006 to 2012. Effect of PCI on short and long term survival was evaluated in both overall and a propensity score-matched cohort...
June 7, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29898149/on-pump-beating-non-beating-cabg-in-stable-angina-have-similar-outcomes
#4
Victor Dayan, Juan Jose Paganini, Alvaro Marichal, Daniel Brusich
OBJECTIVE: On pump beating/non-beating coronary artery bypass grafts (CABG) has been compared in patients with unstable angina and/or severe left ventricular dysfunction. There is scarce evidence regarding the beneficial use of on-pump beating CABG in patients with stable angina and normal left ventricular function. Our aim was to study the postoperative results using both techniques in this group of patients. METHODS: One thousand one hundred and forty-five patients with stable angina underwent on-pump isolated CABG in Uruguay from 2011 to 2015...
March 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29898145/outcomes-following-coronary-artery-bypass-graft-surgery-in-patients-with-mild-preoperative-renal-insufficiency
#5
Weitie Wang, Yuefeng Wang, Rihao Xu, Junwu Chai, Wei Zhou, Honglei Chen, Kai Wang, Xiangrong Kong
INTRODUCTION: Preoperative renal insufficiency is an independent predictor of mortality after coronary artery bypass graft (CABG) surgery. However, there are few reports aimed to evaluate the impact of mild preoperative renal insufficiency on long-term follow-up outcomes after isolated CABG surgery. This study investigates the effect of mild preoperative renal insufficiency on long-term follow-up outcomes of patients after CABG. METHODS: Five hundred eighty-four patients' data that underwent CABG between 1 January 2009 and 1 December 2016 were retrospectively analyzed...
March 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29898141/selenium-vitamin-c-and-n-acetylcysteine-do-not-reduce-the-risk-of-acute-kidney-injury-after-off-pump-cabg-a-randomized-clinical-trial
#6
Shahram Amini, Hojat Naghavi Robabi, Mohammad Abbasi Tashnizi, Vida Vakili
OBJECTIVE: The aim of this study was to investigate the impact of perioperative administration of N-acetylcysteine, selenium and vitamin C on the incidence and outcomes of acute kidney injury after off-pump coronary bypass graft surgery. METHODS: 291 patients requiring elective off-pump coronary bypass graft surgery were randomized to receive either N-acetylcysteine, vitamin C and selenium 600 mg, 1500 mg, 0.5 mg, and nothing orally twice a day, respectively, from the day before to 2 days after surgery...
March 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29898140/aortic-valve-replacement-with-a-conventional-stented-bioprosthesis-versus-sutureless-bioprosthesis-a-study-of-763-patients
#7
Syed Saleem Mujtaba, Simon M Ledingham, Asif Raza Shah, Thasee Pillay, Stephan Schueler, Stephen Clark
OBJECTIVE: The aim of this retrospective study was to compare early postoperative outcomes after aortic valve replacement (AVR) with sutureless bioprostheses and conventional stented bioprostheses implanted through median sternotomy. METHODS: From January 2011 to December 2016, 763 patients underwent aortic valve replacement with bioprostheses; of these, 139 received a Perceval S sutureless valve (Group A) and 624 received a Perimount Magna Ease valve (Group B)...
March 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29897529/clinical-frailty-scale-and-outcome-after-coronary-artery-bypass-grafting
#8
Daniel Reichart, Stefano Rosato, Wail Nammas, Francesco Onorati, Magnus Dalén, Liesa Castro, Riccardo Gherli, Giuseppe Gatti, Ilaria Franzese, Giuseppe Faggian, Marisa De Feo, Sorosh Khodabandeh, Giuseppe Santarpino, Antonino S Rubino, Daniele Maselli, Saverio Nardella, Antonio Salsano, Francesco Nicolini, Marco Zanobini, Matteo Saccocci, Karl Bounader, Eeva-Maija Kinnunen, Tuomas Tauriainen, Juhani Airaksinen, Fulvia Seccareccia, Giovanni Mariscalco, Vito G Ruggieri, Andrea Perrotti, Fausto Biancari
OBJECTIVES: The aim of this study was to assess the impact of frailty on the outcome after coronary artery bypass grafting (CABG) and whether it may improve the predictive ability of European System for Cardiac Operative Risk Evaluation (EuroSCORE II). METHODS: The Clinical Frailty Scale (CFS) was assessed preoperatively in patients undergoing isolated CABG from the multicentre E-CABG registry, and patients were stratified into 3 classes: scores 1-2, scores 3-4 and scores 5-7...
June 11, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29897437/influence-of-a-history-of-cancer-on-long-term-cardiovascular-outcomes-after-coronary-stent-implantation-an-observation-from-coronary-revascularization-demonstrating-outcome-study-kyoto-registry-cohort-2
#9
Kenji Nakatsuma, Hiroki Shiomi, Takeshi Morimoto, Hirotoshi Watanabe, Yoshihisa Nakagawa, Yutaka Furukawa, Kazushige Kadota, Kenji Ando, Koh Ono, Satoshi Shizuta, Takeshi Kimura
Aims: To evaluate the influence of a history of cancer on clinical outcomes in coronary artery disease (CAD) patients who underwent percutaneous coronary intervention (PCI). Methods and Results: In the CREDO-Kyoto PCI/coronary bypass grafting (CABG) Registry Cohort-2, there were 12,180 CAD patients who received PCI with stents. There were 1109 patients with a history of cancer (cancer group), and 11,071 patients without cancer (non-cancer group). The cumulative 5-year incidences of cardiac death and heart failure (HF) hospitalization were significantly higher in the cancer group than in the non-cancer group (12...
April 20, 2018: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29897429/anaortic-coronary-surgery-using-the-%C3%AE-circuit-is-associated-with-a-low-incidence-of-perioperative-neurological-complications
#10
Sotirios Prapas, Antonio Maria Calafiore, Konstantinos P Katsavrias, Ioannis A Panagiotopoulos, Ioannis N Linardakis, Fabrizio Tancredi, Massimiliano Foschi, Michele Di Mauro
OBJECTIVES: Our goal was to compare the observed and the expected rates of postoperative cerebrovascular accidents (CVA) in a large cohort of consecutive patients undergoing off-pump coronary artery bypass grafting (CABG) using the ∏-circuit as a no-touch technique. METHODS: From January 2001 to May 2016, 3081 patients were consecutively submitted to an off-pump CABG operation using the ∏-circuit. A CVA was defined as a neurological deficit, lasting less (transient ischaemic attack) or more (stroke) than 24 h, diagnosed by a neurologist and confirmed by a computed tomography or magnetic resonance imaging scan of the brain...
June 11, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29897262/physiotherapy-mobility-and-walking-management-of-uncomplicated-coronary-artery-bypass-graft-cabg-surgery-patients-a-survey-of-clinicians-perspectives-in-australia-and-new-zealand
#11
Serena Hong, Maree Milross, Jennifer Alison
BACKGROUND: This study aimed to determine current mobility and walking management by physiotherapists of patients undergoing coronary artery bypass graft (CABG) surgery, the clinical milestones expected and physiotherapists' perception of the severity of pain experienced by patients after surgery. DESIGN: Cross sectional study using a questionnaire. METHODS: All hospitals in Australia and New Zealand that perform cardiac surgery (n = 54) were invited to complete a questionnaire...
June 13, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29893681/conversion-of-atrial-fibrillation-after-cardiosurgical-procedures-by-vernakalant%C3%A2-as-an-atrial-repolarization-delaying-agent-arda
#12
Hannan Dalyanoglu, Arash Mehdiani, Jan Philipp Minol, Nihat Firat Sipahi, Hug Aubin, Udo Boeken, Alfred Müller, Hisaki Makimoto, Artur Lichtenberg, Bernhard Korbmacher
Postoperative, new-onset atrial fibrillation (POAF) is one of the most common complications after cardiosurgical procedures. Vernakalant has been reported to be effective in the conversion of POAF. The aim of this study was to evaluate the efficacy and safety of vernakalant for atrial fibrillation after cardiac operations, and to investigate predictors for the success of vernakalant treatment. Patients and Methods: Post-cardiac surgery patients with new-onset of atrial fibrillation (AF) were consecutively enrolled in this study...
May 25, 2018: Heart Surgery Forum
https://www.readbyqxmd.com/read/29893677/prospective-randomized-un-blinded-three-arm-controlled-study-in-coronary-artery-revascularization-with-minimal-invasive-extracorporeal-circulation-systems-miecc-surrogate-parameter-analysis-of-biocompatibility
#13
Arndt H Kiessling, Harald Keller, Anton Moritz
OBJECTIVES: Minimal extracorporeal circulation techniques and systems (MiECC) may reduce the negative side effects of conventional extracorporeal circulation (ECC). However, it is still unclear as to what this is caused by, the reduced priming volume and hemodilution, or the avoidance of blood-air contact and dispersion of mediastinal debris into the systemic circulation. The aim of the trial was the comparison of MiECC to an open ECC setup (openECC) or a system with reduced blood air and debris interaction (closeECC)...
May 16, 2018: Heart Surgery Forum
https://www.readbyqxmd.com/read/29893674/red-cell-distribution-width-with-chads2-and-cha2ds2-vasc-score-is-associated-with-post-operative-atrial-fibrillation-after-coronary-artery-bypass-grafting
#14
Alev Kılıcgedik, Abdulrahman Naser, Ahmet Seyfeddin Gurbuz, Seyhmus Kulahcioglu, Ruken Bengi Bakal, Tuba Unkun, Fatih Yilmaz, Gokhan Kahveci, Cevat Kirma
BACKGROUND: The use of the CHA2DS2-VASc scoring system and red cell distribution width (RDW) as post-op Atrial Fibrillation (POAF) predictors may be promising for the identification of patients that are at a higher risk of POAF. METHODS: A total of 358 patients (57 patients with POAF, and 301 patients with non-POAF ) with sinus rhythm undergoing a coronary artery bypass graft (CABG) operation were included in the study retrospectively. Preoperative RDW levels and electrocardiograms with sinus rhythm were recorded...
May 16, 2018: Heart Surgery Forum
https://www.readbyqxmd.com/read/29893673/gender-differences-in-patients-with-anxiety-after-coronary-artery-bypass-surgery
#15
Yalcin Guzelhan, Cenk Conkbayir, Murat Ugurlucan, Cenk Eray Yildiz, Ufuk Alpagut, Nilgun Bozbuga
The present study was designed to evaluate the relationship between gender and coexisting anxiety in patients undergoing coronary artery surgery. Materials and Methods: A total of 137 patients (41 women and 96 men with a mean age 66.1 ± 6.0 years) patients underwent state and trait anxiety evaluation at baseline (preoperatively) and at six months after (postoperatively) coronary artery bypass graft (CABG). Anxiety symptoms were assessed at enrollment using the Spielberger State-Trait Anxiety Inventory (STAI)...
May 11, 2018: Heart Surgery Forum
https://www.readbyqxmd.com/read/29893671/off-pump-coronary-artery-bypass-grafting-improves-early-clinical-outcomes-including-operative-mortality
#16
Murali P Vettath, Madhu Ravisankar, Tomislov Kopjar, A V Kannan, Nitin Gangadharan
Whether coronary artery bypass grafting (CABG) should be performed on- or off-pump remains a matter of debate. We aim to present our experience with off-pump CABG. Early clinical outcome and adverse events were analyzed over the time course of the study. Methods: A total of 4310 patients undergoing isolated off- pump CABG from January 2002 until December 2016 at the Malabar Institute of Medical Sciences in India were included. Preoperative, intraoperative, and postoperative, as well as follow-up data were prospectively collected...
May 11, 2018: Heart Surgery Forum
https://www.readbyqxmd.com/read/29893420/quantifying-immature-platelets-as-markers-of-increased-platelet-production-after-cabg-surgery
#17
Ke Xu, Noel C Chan, Jack Hirsh, Jeffrey S Ginsberg, Vinai Bhagirath, Paul Kruger, Brian Dale, Mark Crowther, Richard P Whitlock, Chunjian Li, John W Eikelboom
OBJECTIVES: An increased rate of platelet production is a possible cause of reduced antithrombotic response to once-daily aspirin. Markers of immature platelets (IPs), such as immature platelet count (IPC), immature platelet fraction (IPF), and mean platelet volume (MPV) might be useful for identifying patients who have an increase in their rate of platelet production. However, their potential as markers of platelet production have not been rigorously evaluated. We aimed to investigate the utility of the IPC, IPF, and MPV as surrogates for increased platelet production by using coronary artery bypass grafting (CABG) as a model of enhanced thrombopoiesis...
June 12, 2018: European Journal of Haematology
https://www.readbyqxmd.com/read/29888544/should-the-mitral-valve-be-repaired-for-moderate-ischemic-mitral-regurgitation-at-the-time-of-revascularization-surgery
#18
REVIEW
Mohammad Y Salmasi, Amer Harky, Mohammed F Chowdhury, Ali Abdelnour, Anastasia Benjafield, Farah Suker, Stephanie Hubbard, Hunaid A Vohra
BACKGROUND: Ischemic mitral regurgitation (IMR) is associated with increased mortality and recurrent congestive heart failure following coronary artery bypass graft (CABG) surgery. While mitral surgery should be undertaken for severe MR during CABG, the treatment of moderate IMR remains controversial. We conducted a meta-analysis to determine the outcomes of CABG alone and combine with mitral valve repair (MVr) in moderate IMR. METHODS: A literature search was conducted by Pubmed, Ovid, and Embase, which included 643 articles...
June 10, 2018: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29885959/increased-right-atrial-appendage-apoptosis-is-associated-with-differential-regulation-of-candidate-micrornas-1-and-133a-in-patients-who-developed-atrial-fibrillation-after-cardiac-surgery
#19
James N Tsoporis, Anastasia Fazio, Ioannis K Rizos, Shehla Izhar, Gerald Proteau, Vasileos Salpeas, Angelos Rigopoulos, Eleftarios Sakadakis, Ioannis K Toumpoulis, Thomas G Parker
Atrial fibrillation (AF) following on-pump coronary artery bypass grafting (CABG) is a common condition associated with increased morbidity and mortality. We investigated the possibility that miRs may play a contributory role in postoperative AF and associated apoptosis. A total of 42 patients (31 males and 11 females, mean age 65.0 ± 1.3 years) with sinus rhythm and without a history of AF were prospectively enrolled. We examined the levels of the muscle-specific miRs 1 and 133A and markers of apoptosis including TUNEL staining, caspase-3 activation, Bcl2 and Bax mRNAs in right atrial appendage (RAA) biopsies and blood plasma taken before aortic cross-clamping and after reperfusion...
June 7, 2018: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/29883468/wider-perioperative-glycemic-fluctuations-increase-risk-of-postoperative-atrial-fibrillation-and-icu-length-of-stay
#20
Ming Ann Sim, Weiling Liu, Sophia T H Chew, Lian Kah Ti
INTRODUCTION: Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery associated with increased morbidity and mortality. Although sustained hyperglycemia is a known risk factor of AF and poor ICU outcomes, emerging in-vitro studies reveal acute glycemic fluctuations to be an additional independent predictor of AF. The effect of acute glycemic fluctuations on the incidence of POAF in the clinical setting remains unclear. We aim to investigate the effect of the magnitude of acute perioperative glycemic fluctuations on the incidence of POAF in a multi-ethnic Southeast-Asian population...
2018: PloS One
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