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https://www.readbyqxmd.com/read/28537882/correlation-between-apparent-diffusion-coefficient-adc-and-cellularity-is-different-in-several-tumors-a-meta-analysis
#1
Alexey Surov, Hans Jonas Meyer, Andreas Wienke
The purpose of this meta-analysis was to provide clinical evidence regarding relationship between ADC and cellularity in different tumors based on large patient data.Medline library was screened for associations between ADC and cell count in different tumors up to September 2016. Only publications in English were extracted. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (PRISMA) was used for the research.Overall, 39 publications with 1530 patients were included into the analysis...
May 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28535495/understanding-the-heterogeneity-of-cervical-cancer-screening-non-participants-data-from-a-national-sample-of-british-women
#2
Laura A V Marlow, Amanda J Chorley, Jessica Haddrell, Rebecca Ferrer, Jo Waller
BACKGROUND: Uptake of cervical cancer screening in the United Kingdom (UK) is falling year on year, and a more sophisticated understanding of non-participation may help design interventions to reverse this trend. This study ascertained the prevalence of different non-participant types using the Precaution Adoption Process Model (PAPM). METHODS: Home-based computer-assisted interviews were carried out with 3113 screening-eligible women in Britain. Survey items assessed self-reported screening uptake and intention to attend in future...
May 20, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28534383/in-vitro-anticancer-activity-and-cytotoxicity-screening-of-phytochemical-extracts-from-selected-traditional-chinese-medicinal-plants
#3
Chao Liang, Hui Pan, Haizhou Li, Yang Zhao, Yang Feng
PURPOSE: The purpose of this study was to evaluate the anticancer activity of 10 selected traditional Chinese medicinal plants on 4 cancer cell lines, namely MCF-7 (breast carcinoma), BALL-1 (acute lymphoblastic leukemia), Huh-7 (hepatocellular carcinoma), HeLa (cervical carcinoma) and their cytotoxicity on a normal cell line, namely MCF-10A (non-tumorigenic mammary epithelial line), about which there were few reports previously. METHODS: Six phytochemical extracts, namely petroleum ether extract (PEE), chloroform extract (CE), ethyl acetate extract (EAE), n-butanol extract (BE), the remainder after extraction (RE) and water extract (WE) from each plant were prepared...
March 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28533763/is-alteration-of-tuning-property-in-cervical-vestibular-evoked-myogenic-potential-specific-for-m%C3%A3-ni%C3%A3-re-s-disease
#4
Toshihisa Murofushi, Masahito Tsubota, Ryota Suizu, Eriko Yoshimura
OBJECTIVE: The aim of this study is to show sensitivity and specificity of cervical vestibular-evoked myogenic potential (cVEMP) tuning property test to Ménière's disease (MD) in comparison with healthy controls (HC) and patients with other vestibular diseases. SUBJECTS: Totally 92 subjects (50 women and 42 men, 20-77 years of age) were enrolled in this study. Subjects were composed of 38 definite unilateral MD patients, 11 unilateral benign paroxysmal positional vertigo patients, 14 vestibular migraine patients, 19 unilateral vestibular neuritis patients, and 10 HC...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28532334/cervical-cancer-prevention-related-knowledge-and-attitudes-among-female-undergraduate-students-from-different-ethnic-groups-within-china-a-survey-based-study
#5
Enqi Wu, Sarah M Tiggelaar, Tao Jiang, Huanhu Zhao, Ritu Wu, Rilige Wu, Fangmei Xu
The purpose of this study was to understand cervical cancer prevention-related knowledge and attitudes among female undergraduate students from different ethnic groups within China. We conducted a survey among ethnically diverse female students from the Minzu University of China, in Beijing in October, 2014. RESULTS: Questionnaires from 493 participants aged from 16 to 26 years old were included in the final database. The seven ethnic groups included in the final analysis were Han, Korean, Mongolian, Uyghur, Tibetan, Hui and Tujia...
May 22, 2017: Women & Health
https://www.readbyqxmd.com/read/28531261/age-of-acquiring-causal-human-papillomavirus-hpv-infections-leveraging-simulation-models-to-explore-the-natural-history-of-hpv-induced-cervical-cancer
#6
Emily A Burger, Jane J Kim, Stephen Sy, Philip E Castle
Background.: Although new human papillomavirus (HPV) infections can occur at all ages, the age at which women acquire their "causal" HPV infection that develops into cervical cancer is poorly understood and practically unobservable. We aimed to estimate the age distribution at which individuals acquired their causal HPV infection in the absence of HPV vaccination or screening to help guide the optimal use of both. Methods.: Using an empirically calibrated mathematical model that simulates the natural history of cervical cancer, we estimated the cumulative number of causal HPV infections by age, stratified by HPV genotype (HPV16 vs...
May 20, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28531212/epidemiological-investigation-of-the-relationship-between-common-lower-genital-tract-infections-and-high-risk-human-papillomavirus-infections-among-women-in-beijing-china
#7
Dai Zhang, Ting Li, Lei Chen, Xiaosong Zhang, Gengli Zhao, Zhaohui Liu
BACKGROUND: The incidence of lower genital tract infections in China has been increasing in recent years. The link between high-risk human papillomavirus (HR-HPV) and other sexually transmitted diseases (STDs) remains unclear. METHODS: From March to October 2014, gynecological examinations and questionnaires were conducted on 1218 married women. Cervical secretions and vaginal swab specimens were tested for Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Ureaplasma urealyticum (UU), yeast, clue cells and HR-HPV...
2017: PloS One
https://www.readbyqxmd.com/read/28531205/cost-analysis-of-human-papillomavirus-related-cervical-diseases-and-genital-warts-in-swaziland
#8
Themba G Ginindza, Benn Sartorius, Xolisile Dlamini, Ellinor Östensson
BACKGROUND: Human papillomavirus (HPV) has proven to be the cause of several severe clinical conditions on the cervix, vulva, vagina, anus, oropharynx and penis. Several studies have assessed the costs of cervical lesions, cervical cancer (CC), and genital warts. However, few have been done in Africa and none in Swaziland. Cost analysis is critical in providing useful information for economic evaluations to guide policymakers concerned with the allocation of resources in order to reduce the disease burden...
2017: PloS One
https://www.readbyqxmd.com/read/28530515/cost-effectiveness-of-strategies-to-increase-cervical-screening-uptake-at-first-invitation-strategic
#9
Apostolos Tsiachristas, Matthew Gittins, Henry Kitchener, Alastair Gray
Objective To assess the cost-effectiveness of strategies to increase cervical cancer screening uptake at first invitation (STRATEGIC trial). Methods We performed an economic analysis alongside the STRATEGIC trial, comparing each of seven novel interventions for improving cervical screening uptake with control general practices in Greater Manchester and Grampian (United Kingdom). A template was developed to measure the intervention costs. Trial estimates of screening uptake were combined with data from the literature to estimate healthcare costs of each intervention...
January 1, 2017: Journal of Medical Screening
https://www.readbyqxmd.com/read/28530514/public-understanding-of-the-purpose-of-cancer-screening-a-population-based-survey
#10
Amanda J Chorley, Yasemin Hirst, Charlotte Vrinten, Christian von Wagner, Jane Wardle, Jo Waller
Objectives In examining informed choice in cancer screening, we investigated public awareness that some screening programmes aim to prevent cancer, while others seek to detect cancer at an early stage. Methods A population-based survey of adults aged 50-70 in England (n = 1433), including data on demographic characteristics and screening experience. Participants were asked to select the main purpose of cervical, breast, and colorectal cancer screening (both faecal occult blood testing and flexible sigmoidoscopy)...
January 1, 2017: Journal of Medical Screening
https://www.readbyqxmd.com/read/28530513/a-cluster-randomized-trial-of-strategies-to-increase-uptake-amongst-young-women-invited-for-their-first-cervical-screen-the-strategic-trial
#11
H Kitchener, M Gittins, M Cruickshank, C Moseley, S Fletcher, R Albrow, A Gray, L Brabin, D Torgerson, E J Crosbie, A Sargent, C Roberts
Objectives To measure the feasibility and effectiveness of interventions to increase cervical screening uptake amongst young women. Methods A two-phase cluster randomized trial conducted in general practices in the NHS Cervical Screening Programme. In Phase 1, women in practices randomized to intervention due for their first invitation to cervical screening received a pre-invitation leaflet and, separately, access to online booking. In Phase 2, non-attenders at six months were randomized to one of: vaginal self-sample kits sent unrequested or offered; timed appointments; nurse navigator; or the choice between nurse navigator or self-sample kits...
January 1, 2017: Journal of Medical Screening
https://www.readbyqxmd.com/read/28530494/review-anal-intraepithelial-neoplasia-in-hiv-infected-men-who-have-sex-with-men-is-screening-and-treatment-justified
#12
Peter Wasserman, David S Rubin, Glenn Turett
Anal squamous cell carcinoma (SCC) is the fourth most prevalent cancer in human immunodeficiency virus (HIV)-infected men who have sex with men (MSM). Human papillomavirus (HPV) has been detected in over 90% of anal carcinoma biopsy specimens from MSM, and is considered a necessary, but alone, insufficient factor for carcinogenesis. Anal intraepithelial neoplasia (AIN) may be precursive for SCC, and screening cytology with referral of persons with abnormality for high-resolution anoscopy-guided biopsy, and AIN treatment, has been recommended for prevention...
May 22, 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28530319/-implementation-of-a-national-screening-program-for-detection-of-malignant-and-pre-malignant-cervical-morbidity-in-israel
#13
REVIEW
Ravit Bassal, Eduardo Schejter, Daniel Cohen, Lital Keinan-Boker
The natural development of cervical cancer, which takes many years, is mostly initiated by infection with human papillomavirus (HPV) and is characterized by the development of precancerous lesions, cervical intraepithelial neoplasia 3 (CIN3), which are defined as abnormal changes in epithelial cells that cover the cervix surface. Since the pre-cancerous process is microscopic and asymptomatic, early detection is based on cytological screening, the Pap test. In Israel, Pap tests are performed based on selfreferral for testing and not within the framework of a national screening program because of the low incidence rate of cervical cancer in Israel...
January 2017: Harefuah
https://www.readbyqxmd.com/read/28530082/-cervical-cancer-in-israel-2016-facts-insights-and-thoughts-for-the-future
#14
REVIEW
Menahem Fisher, Eduardo Schejter, Ido Solt, Gad Renart
The natural history of precancerous lesions and cervical cancer in Israeli women differs from that reported in the world. In 2011, 244 women were diagnosed in Israel with invasive cervical cancer, with the mortality of 79 women. The incidence of cervical cancer in Israel is about 5 new cases per year per 100,000 women (5.4 Jewish, 3.2 Arab). This figure is very low compared with statistics presented in other countries and has not changed over the last decades. The vast majority of Israeli women were diagnosed due to symptoms and not following Pap smear screening...
September 2016: Harefuah
https://www.readbyqxmd.com/read/28529583/evaluation-of-microrna-205-expression-as-a-potential-triage-marker-for-patients-with-low-grade-squamous-intraepithelial-lesions
#15
Hong Xie, Ingrid Norman, Anders Hjerpe, Tomislav Vladic, Catharina Larsson, Weng-Onn Lui, Ellinor Östensson, Sonia Andersson
High-risk human papillomavirus (HPV) testing is a recommended triage approach for females with atypical squamous cells of undetermined significance (ASCUS), but due to its poor specificity this approach is not recommended for patients with low-grade squamous intraepithelial lesions (LSIL). The objective of the current study was to determine microRNA (miR)-205 expression levels in liquid-based cytology (LBC) samples, and evaluate their ability to predict cervical intraepithelial neoplasia grade 2/3 or worse (CIN2/3+) in females with minor cytological abnormalities...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28529541/differences-in-age-specific-hpv-prevalence-between-self-collected-and-health-personnel-collected-specimen-in-a-cross-sectional-study-in-ghana
#16
Adolf K Awua, Richard M K Adanu, Edwin K Wiredu, Edwin A Afari, Alberto Severini
BACKGROUND: HPV infections are ubiquitous and particularly common among sexually active young women. However, there are regional and national variations in age-specific HPV prevalence, which have implications for cervical cancer control. Data on age-specific HPV prevalences for Ghana and most sub-Saharan countries are scanty. Therefore, this study primarily sought to determine the age-specific HPV prevalence among women in a Ghanaian community and to determine whether these prevalences determined with health-personnel and self-collected specimens were comparable...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28528899/effect-of-professional-society-recommendations-on-women-s-desire-for-a-routine-pelvic-examination
#17
George F Sawaya, Karen K Smith-McCune, Steven E Gregorich, Michelle Moghadassi, Miriam Kuppermann
BACKGROUND: The American College of Physicians strongly recommends against performing pelvic examinations in asymptomatic, nonpregnant women, citing evidence of harm (false-positive testing, unnecessary surgery) and no evidence of benefit. In contrast, the American Congress of Obstetricians and Gynecologists recommends pelvic examinations in asymptomatic women beginning at age 21 years, citing expert opinion. OBJECTIVE: We sought to evaluate if providing women with professional societies' conflicting statements about pelvic examinations (recommendations and rationales) would influence their desire for a routine examination...
May 18, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28525628/modulation-of-the-muscle-activity-during-sleep-in-cervical-dystonia
#18
E Antelmi, R Ferri, F Provini, C Scaglione, F Mignani, F Rundo, S Vandi, M Fabbri, F Pizza, G Plazzi, P Martinelli, R Liguori
Introduction: Impaired sleep has been reported as an important non-motor feature in dystonia, but so far, subjective complaints have never been compared with nocturnal video-polysomnographic recording, which is the gold standard to assess sleep-related disorders. Methods: Twenty patients with idiopathic isolated cervical dystonia and 22 healthy controls underwent extensive clinical investigations, neurological examination and questionnaires screening for excessive daytime sleepiness and sleep-related disorders...
May 19, 2017: Sleep
https://www.readbyqxmd.com/read/28525467/analysis-of-cervical-angiograms-in-cervical-spine-trauma-patients-does-it-make-a-difference
#19
Tina Dreger, Howard Place, Theresa Mattingly, Christine Piper, Jennifer Brechbuehler
STUDY DESIGN: Retrospective review. OBJECTIVE: To evaluate computed tomography angiogram (CTA) use for diagnosing blunt vertebral artery injury (BVAI) at a single institution, to assess the incidence of BVAI in the studied population, and determine if diagnosis affected care. We also wanted to evaluate if testing and treatment resulted in complications. SUMMARY OF BACKGROUND DATA: BVAI is an example of a previously underdiagnosed injury. Ease of CTA has simplified vertebral artery evaluation...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28523291/review-of-the-biotechnologies-and-tests-used-for-precancerous-cervical-lesions-diagnosis
#20
Ruxandra Viorica Stănculescu, Elvira Brătilă, Vasilica Bauşic, Teodora Camelia Vlădescu, Florina Vasilescu, Alexandra Bauşic, Costin Berceanu
This paper draws on the author's extensive experience in the clinical research focused on the implementation of the new biotechnologies able to identify precancerous cervical lesions and is intended to be a systematic approach to new achievements. The goal of this review is to provide updated information concerning the significance of each biotechnology used in clinical medicine to screen women for cervical cancer or to allow a pertinent discrimination between spontaneous remission lesions and progressive lesions...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
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