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JOURNAL ARTICLE
Agathe van Lamsweerde, Jack T Pearson, Rachel Urrutia, Kristina Gemzell-Danielsson, Helena Kopp Kallner, Anita Nelson, Eleonora Benhar, Carlotta Favaro, Elina Berglund Scherwitzl, Raoul Scherwitzl
Background: Previous investigations of time-to-pregnancy recognition have analysed data from national surveys and clinics, but this has not been investigated in the context of digital fertility applications. Timely pregnancy recognition can help individuals in health and pregnancy management, reducing maternal and foetal risk and costs, whilst increasing treatment options, availability, and cost. Methods: This dataset contained 23,728 pregnancies (conceived between June 2018 and December 2022) from 20,429 participants using a Food and Drug Administration (FDA) cleared fertility app in the United States...
December 2024: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
#2
REVIEW
Ahmet Cetinkaya, S Irem Kaya, Fatma Budak, Sibel A Ozkan
Ovarian cancer, which affects the female reproductive organs, is one of the most common types of cancer. Since this type of cancer has a high mortality rate from gynaecological cancers, the scientific community shows great interest in studies on its treatment. Chemotherapy, radiotherapy, and surgical treatment methods are used in its treatment. In the absence of targeted treatments in these treatment methods, side effects occur in patients, and patients show resistance to the drug. In addition, the underlying causes of ovarian cancer are still not fully known...
April 17, 2024: Critical Reviews in Analytical Chemistry
#3
JOURNAL ARTICLE
Fabiola Giudici, Angela De Paoli, Federica Toffolutti, Stefano Guzzinati, Silvia Francisci, Lauro Bucchi, Gemma Gatta, Elena Demuru, Sandra Mallone, Antonella Dal Cin, Adele Caldarella, Francesco Cuccaro, Enrica Migliore, Maria Letizia Gambino, Alessandra Ravaioli, Antonella Puppo, Margherita Ferrante, Giuliano Carrozzi, Fabrizio Stracci, Antonino Musolino, Cinzia Gasparotti, Rossella Cavallo, Walter Mazzucco, Maria Francesca Vitale, Giuseppe Cascone, Paola Ballotari, Stefano Ferretti, Lucia Mangone, Roberto Vito Rizzello, Giuseppe Sampietro, Michael Mian, Lorenza Boschetti, Rocco Galasso, Francesca Bella, Daniela Piras, Alessandra Sessa, Pietro Seghini, Anna Clara Fanetti, Pasquala Pinna, Roberta De Angelis, Diego Serraino, Luigino Dal Maso, Airtum Working Group
This study aims to estimate long-term survival, cancer prevalence, and several cure indicators for Italian women with gynaecological cancers. Thirty-one cancer registries, representing 47% of the Italian female population, were included. Mixture cure models were used to estimate Net Survival (NS), Cure Fraction, Time To Cure (5-year conditional NS>95%), Cure Prevalence (women who will not die of cancer), and Already Cured (living longer than Time to Cure). In 2018, 0.4% (121,704) of Italian women were alive after corpus uteri cancer, 0...
April 15, 2024: American Journal of Epidemiology
#4
REVIEW
Sarah E Umetsu, Nicholas R Ladwig
The current understanding of inflammatory myofibroblastic tumours (IMTs) of the gynaecological tract has recently been enhanced by their increased recognition. This increase is largely due to greater accessibility to RNA-based molecular assays used to identify their defining ALK rearrangements. This review summarises the clinical characteristics, morphological spectrum, immunohistochemical profile and molecular underpinnings of uterine IMT. Additionally, this review discusses practical diagnostic considerations including overlap between uterine IMT and smooth muscle tumours as well as pregnancy-associated uterine IMT...
April 17, 2024: Histopathology
#5
JOURNAL ARTICLE
Agnes Rygaard, Maria Jonsson, Anna-Karin Wikström, Sophia Brismar-Wendel, Susanne Hesselman
OBJECTIVE: To investigate whether perineal wound complications in the first birth, alone or in conjunction with obstetric anal sphincter injury (OASI), is associated with an increased risk of OASI in the second birth. DESIGN: Nationwide population-based cohort study. SETTING: Sweden. POPULATION: Women (n = 411 317) with first and second singleton vaginal births in Sweden, 2001-2019. METHODS: Data on diagnostic codes and surgical procedures were retrieved from the Swedish Medical Birth Register and the Swedish Patient Register...
April 16, 2024: BJOG: An International Journal of Obstetrics and Gynaecology
#6
JOURNAL ARTICLE
Laura Cattani, Dominique Van Schoubroeck, Christine De Bruyn, Sophie Ghesquière, Jan Deprest
OBJECTIVE: To determine the prevalence of pelvic floor dysfunction (PFD) among pregnant women, their clustering and their association with body image disturbance (BID) up to 1 year postpartum. DESIGN: Monocentric prospective cohort study. SETTING: University Hospitals Leuven. POPULATION: Pregnant women attending for pregnancy care, first assessed prior to 14 weeks of gestation and agreeing to follow-up until 1 year postpartum...
April 16, 2024: BJOG: An International Journal of Obstetrics and Gynaecology
#7
JOURNAL ARTICLE
Masamitsu Nakamura, Akihiko Sekizawa, Junichi Hasegawa, Masahiko Nakata, Shinji Katsuragi, Hiroaki Tanaka, Takeshi Murakoshi, Naohiro Kanayama, Isamu Ishiwata, Tomoaki Ikeda
AIM: In Japan, unlike Western countries, tocolytic agents are administered in long-term protocols to treat threatened preterm labor. Evaluating the side effects of this practice is crucial. We examined whether ritodrine hydrochloride had been administered in cases of maternal death, aiming to investigate any relationship between ritodrine administration and maternal death. METHODS: This retrospective cohort study used reports of maternal deaths from multiple institutions in Japan between 2010 and 2020...
April 16, 2024: Journal of Obstetrics and Gynaecology Research
#8
JOURNAL ARTICLE
Melanie A M Baas, Claire A I Stramrood, Jolijn E Molenaar, Petra M van Baar, Joost W Vanhommerig, Maria G van Pampus
BACKGROUND: Obstetrician-Gynaecologists (ObGyns) frequently face work-related adverse events such as severe obstetric complications and maternal or neonatal deaths. In 2014, the WATER-1 study showed that ObGyns are at risk of developing work-related posttraumatic stress disorder (PTSD), while many hospitals lacked a professional support system. The aim of the present study is to evaluate the current prevalence of work-related traumatic events and mental health problems among Dutch ObGyns, as well as to examine the current and desired support...
April 16, 2024: BMC Psychiatry
#9
JOURNAL ARTICLE
Tetsuya Matsukawa, Nobuhisa Yoshikawa, Wenting Liu, Satomi Hattori, Kosuke Yoshida, Masato Yoshihara, Satoshi Tamauchi, Akira Yokoi, Kaoru Niimi, Hiroaki Kajiyama
BACKGROUND: To investigate the role of CD47 expression and its relationship with tumor-resident macrophages, specifically at the tumor margin, in patients with type II endometrial cancer. This study aims to elucidate whether CD47 could serve as a prognostic marker and to understand the dynamics between CD47 and macrophages, which could inform new therapeutic strategies. METHODS: A retrospective cohort study was conducted involving 75 patients of type II endometrial...
April 16, 2024: Journal of Obstetrics and Gynaecology Research
#10
JOURNAL ARTICLE
Fatih Şahin, Savaş Özdemir, Ozan Doğan
AIM: Laparoscopic lateral suspension is a novel approach for repairing anterior and apical pelvic organ prolapse (POP). According to integral theory, urinary symptoms and pelvic pain are believed to originate from suspensory ligaments. We aimed to investigate the objective and subjective outcomes of adding sacroterine plication to apical prolapse surgery. METHODS: Sixty patients with Grade 2 or higher symptomatic apical POP were included in the study. The study sample was categorized into two groups: Group 1 underwent lateral suspension and Group 2 underwent lateral suspension and sacroterine plication...
April 16, 2024: Journal of Obstetrics and Gynaecology Research
#11
JOURNAL ARTICLE
Eiji Nishio, Ken Ishitani, Takahide Arimoto, Toshio Igarashi, Tetsuya Ishikawa, Akira Iwase, Mariko Ogawa, Nobuaki Ozawa, Hiroaki Kajiyama, Kaoru Kawasaki, Risa Kudo, Jun Kumakiri, Hiroko Komura, Kan Komai, Seiya Sato, Koichi Shinohara, Toshifumi Takahashi, Kyoko Tanaka, Kyoko Tanebe, Masashi Deguchi, Akiko Tozawa-Ono, Akitoshi Nakashima, Mikiya Nakatsuka, Satoshi Hayakawa, Tetsuya Hirata, Rie Fukuhara, Yasuka Miyakuni, Hiroaki Miyazaki, Tohru Morisada, Yoshimitsu Kuwabara, Masataka Takenaka, Makio Shozu, Mayumi Sugiura-Ogasawara, Tsugio Maeda, Yoshihito Yokoyama, Takuma Fujii
Twelve years after the first edition of The Guideline for Gynecological Practice, which was jointly edited by The Japan Society of Obstetrics and Gynecology and The Japan Association of Obstetricians and Gynecologists, the 5th Revised Edition was published in 2023. The 2023 Guidelines includes 5 additional clinical questions (CQs), which brings the total to 103 CQ (12 on infectious disease, 30 on oncology and benign tumors, 29 on endocrinology and infertility and 32 on healthcare for women). Currently, a consensus has been reached on the Guidelines, and therefore, the objective of this report is to present the general policies regarding diagnostic and treatment methods used in standard gynecological outpatient care that are considered appropriate...
April 16, 2024: Journal of Obstetrics and Gynaecology Research
#12
JOURNAL ARTICLE
Siti Nawwal Ahmad Nasfy, Habibah Abdul Hamid, Azalea Md Khairuddin, Maryam Kameelah Mohamad Fauzi
Gliomatosis peritonei (GP) and Growing Teratoma Syndrome (GTS) are rare and clinically significant conditions often associated with ovarian teratomas. GP involves the development of benign glial implants on the peritoneal surface, while GTS is characterised by the growth of benign, yet enlarging peritoneal implants following chemotherapy for malignant germ cell tumours. These implants are typically histologically mature teratomas devoid of malignancy. Our report documents a unique case where both GP and GTS manifested in a patient undergoing treatment for an immature ovarian teratoma...
April 16, 2024: BMJ Case Reports
#13
JOURNAL ARTICLE
Yuru Wang, Xiaoling Miao, Pramon Viwattanakulvanid
INTRODUCTION: Perimenopause is a critical transitional period in reproductive ageing. A set of physiological and psychological changes can affect perimenopausal women's quality of life and further threaten their older adult health conditions. In China, less than one-third of midlife women with menopausal symptoms have actively sought professional healthcare. Regarding the public health significance of comprehensive menopause management, the current study aims to investigate the effects of a therapeutic lifestyle modification (TLM) intervention on cardiometabolic health, sexual functioning and health-related quality of life among perimenopausal Chinese women...
April 15, 2024: BMJ Open
#14
JOURNAL ARTICLE
Dian Zhang, He Cai, Jinlin Xie, Lijuan Chen, Zhou Zhang, Juanzi Shi
OBJECTIVES: To assess the age-specific cumulative live birth rates (CLBRs) in intrauterine insemination (IUI) cycles using either donor or husband sperm, and to investigate the impact of sperm sources on IUI success among women within the same age group. METHODS: This retrospective cohort study comprised women who underwent IUI with donor sperm (IUI-D) or husband sperm (IUI-H) from 2017 to 2021. The women were stratified based on their age at the initiation of insemination into four categories: <35, 35-37, 38-39 and ≥40 years...
April 16, 2024: International Journal of Gynaecology and Obstetrics
#15
JOURNAL ARTICLE
Cristina Sánchez-Cuerda, Margarita Elices, Paloma Lobo, Yasmina Cabrera, Silvia Duch, Alicia García, José Rubio, Julio Álvarez, Pilar Álvarez
OBJECTIVE: To determine whether adenomyosis is present in the cornual portion of hysterectomies of symptomatic sterilization device users and in patients hysterectomized for different benign causes and who presented with pelvic pain and/or menstrual alterations. METHODS: An observational, analytical, cross-sectional, single-center, retrospective cohort study was conducted in a secondary level hospital. Cohort 1 consisted of women who had Essure® hysteroscopic sterilization devices inserted between 2009 and 2017, who developed gynecologic symptoms (pelvic pain, heavy menstrual bleeding, and/or abnormal uterine bleeding) and who underwent a hysterectomy for explantation of the devices...
April 16, 2024: International Journal of Gynaecology and Obstetrics
#16
JOURNAL ARTICLE
Daniela Agostinho David, Rafaela Pires, Maria João Fonseca, Miguel Xavier, Miguel Branco
OBJECTIVE: This study aimed to evaluate the disparity of the expectations and basic knowledge of prenatal ultrasound (US) screening among pregnant women and make a comparison with the current scientific knowledge and national recommendations. We hypothesize that sociodemographic factors, including age, education, and professional occupation, may be associated with different levels of knowledge. METHODS: This was a cross-sectional study performed in 2021 of 336 women aged 18 to 46 years in a maternity facility in a tertiary hospital in Portugal...
April 16, 2024: International Journal of Gynaecology and Obstetrics
#17
JOURNAL ARTICLE
Anne M de Korte, Belle H de Rooij, Dorry Boll, Ingrid van Loon, Noor Vincent, Meeke Hoedjes, Chantal R M Lammens, Floor Mols, Marije L van der Lee, M Caroline Vos, Nicole P M Ezendam
OBJECTIVES: Lifestyle promotion during follow-up consultations may improve long-term health and quality of life in endometrial cancer patients. This study aimed to identify barriers and facilitators to improve and sustain a healthy lifestyle that can be translated to behavioral methods and strategies for lifestyle counseling. METHODS: Endometrial cancer patients from three hospitals were recruited to participate in a semi-structured interview. The data were transcribed and coded...
December 2024: Journal of Psychosomatic Obstetrics and Gynaecology
#18
JOURNAL ARTICLE
Raneen Abu Shqara, Gabriela Goldinfeld, Roni Tenne Cohen, Sari Nahir Biderman, Lior Lowenstein, Maya Frank Wolf
OBJECTIVES: At our center, natural home-like delivery settings have been established in or near conventional labor wards, for the care of pregnant women who prefer little or no medical intervention during labor and birth. We compared obstetrical and neonatal outcomes of women in active spontaneous labor, between those who chose to deliver in a natural-delivery setup and those who chose a conventional setting. METHODS: This retrospective study included low-risk women who delivered at term between March 1, 2020 and December 31, 2022, in a single tertiary university affiliated medical center...
April 15, 2024: Journal of Obstetrics and Gynaecology Research
#19
JOURNAL ARTICLE
Wei Chen, Zhuyu Li, Dongyu Wang, Zilian Wang
PURPOSE: To investigate the association between neonatal birthweight (NBW) discordance and preeclampsia (PE) in twin pregnancy. METHODS: This was a single-center retrospective cohort study. Women with two live births in the First Affiliated Hospital of Sun Yat-sen University from January 2011 to June 2020 were eligible. They were classified into four groups based on the quartiles of NBW discordance in monochorionic (MC) and dichorionic (DC) twin pregnancy. The relationship between NBW discordance and the risk of PE was assessed by logistic regression, subgroup analyses was further analyzed...
April 15, 2024: Journal of Obstetrics and Gynaecology Research
#20
JOURNAL ARTICLE
Adi Dayan-Schwartz, Suzan Abd Elgani, Tamam Abdul-Ghani, Liron Kogan, Ari Reiss, Alon Tal
OBJECTIVE: The aim of the present study was to compare accuracy, safety and cost-effectiveness of three β-hCG measurements protocols, applied in managing ectopic pregnancies (EP) with methotrexate (MTX): (1) day 1 to 7 β-hCG levels, (2) day 1 to 4 β-hCG levels and (3) day 4 to 7 β-hCG levels. METHODS: Cost-minimization analysis (CMA) based on a retrospective study of patients treated with single-dose MTX for EP, was evaluated at a single institution between January 2001 to May 2021...
April 15, 2024: International Journal of Gynaecology and Obstetrics
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