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Kerry Hancuch, Jared Baeten, Kenneth Ngure, Connie Celum, Nelly Mugo, Edna Tindimwebwa, Renee Heffron
For HIV-1 serodiscordant couples, HIV-1 exposure and risk of transmission is heightened during pregnancy attempts, but safer conception strategies can reduce risk. As safer conception programs are scaled up, understanding couples' preferences and experiences can be useful for programmatic recommendations. We followed 1013 high-risk, heterosexual HIV-1 serodiscordant couples from Kenya and Uganda for two years in an open-label delivery study of integrated pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART), the Partners Demonstration Project...
February 17, 2018: AIDS Care
A Schröder, F A Campbell, W A Farhat, J L Pippi Salle, D J Bägli, A J Lorenzo, M A Koyle
INTRODUCTION: There are limited data about pain patterns, analgesic requirements and factors predicting opioid requirements of children undergoing outpatient urologic surgery. This prospective study aimed to assess recovery profiles and pain medication requirements. METHODS: Patients between 6 months and 12 years of age were recruited prospectively between December 2013 and June 2014. Demographic and operative characteristics were collected. Following discharge home, the parents were asked to administer both acetaminophen and ibuprofen Q6H at a weight-adjusted dose, based on a schedule, until the end of postoperative day 2, and to administer the medication as required on postoperative day 3...
January 31, 2018: Journal of Pediatric Urology
Fatih Alper Akcan, Yusuf Dündar, Hümeyra Bayram Akcan, Ahmet Uluat, Derya Cebeci, Mehmet Ali Sungur, İlhan Ünlü
OBJECTIVE: To investigate the clinical role of Vitamin D in prognosis of Otitis media with effusion. METHODS: This prospective-controlled study was conducted at otolaryngology department in Duzce University, Turkey. The study group comprised children who were diagnosed with Otitis media with effusion between September 2016 and February 2017. Control group was conducted with children underwent circumcision or inguinal hernia repair operations that confirmed with ENT examination they do not have any sign of otitis media...
February 2018: International Journal of Pediatric Otorhinolaryngology
Robert C Bailey, Irene Nyaboke, Mary Ellen Mackesy-Amiti, Erick Okello, Valentine Pengo, Betha Ochomo, Mary Emmaculate Auma, Simon Were, Stella Ojuok, Evelyne Adoyo, Mildred Adhiambo, Marisa R Young, Rebeca M Plank, Fredrick O Otieno
BACKGROUND: As countries scale up adult voluntary medical male circumcision (VMMC) for HIV prevention, they are looking ahead to long term sustainable strategies, including introduction of early infant male circumcision (EIMC). Although a number of devices for EIMC are prequalified by the World Health Organization, evaluation of additional devices can provide policy-makers and clinicians the information required to make informed decisions. We undertook a field evaluation of the safety and acceptability of the AccuCirc device in Kisumu County, Kenya...
2018: PloS One
Edward Nelson Kankaka, Joseph Ssekasanvu, Jessica Prodger, Dorean Nabukalu, Hadijja Nakawooya, Anthony Ndyanabo, Godfrey Kigozi, Ronald Gray
OBJECTIVE: To determine whether circumcision of HIV-positive men is associated with increased subsequent sexual risk behaviors which may place their female partners at risk. METHODS: Newly circumcised and uncircumcised HIV-positive men in the Rakai Community Cohort Study were followed from baseline (July 2013-January 2015) to determine trend in sexual risk behaviors and association of circumcision with subsequent sexual risk behaviors at follow up (February 2015-September 2016)...
February 13, 2018: AIDS Care
Elijah Odoyo-June, Kawango Agot, Edward Mboya, Jonathan Grund, Paul Musingila, Donath Emusu, Leonard Soo, Boaz Otieno-Nyunya
BACKGROUND: Self-reported male circumcision (MC) status is widely used to estimate community prevalence of circumcision, although its accuracy varies in different settings depending on the extent of misreporting. Despite this challenge, self-reported MC status remains essential because it is the most feasible method of collecting MC status data in community surveys. Therefore, its accuracy is an important determinant of the reliability of MC prevalence estimates based on such surveys...
2018: PloS One
Haitham A Torky, Anwar A Elshenawy, Ali M Ahmad
No abstract text is available yet for this article.
February 8, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
Amy Martin, Ramesh Nataraja, Chris Kimber, Maurizio Pacilli
INTRODUCTION: Tissue glue has been used for circumcision in children with promising results. We aimed to evaluate the efficacy of tissue glue in pediatric circumcision. MATERIALS AND METHODS: A systematic review and meta-analysis of the English literature (1997-2017) was conducted according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement on children that underwent circumcision with tissue glue. Meta-analysis was conducted using RevMan 5...
January 30, 2018: Urology
Fahad A Alyami, Zhoobin Heidari Bateni, Raken Odeh, Walid A Farhat, Martin Koyle
INTRODUCTION: Circumcision is one of the most widely performed procedures in the world. One of the indications for circumcision is Lichen sclerosis (LS). The natural history of LS in children is not as well-documented as in adult patients. Surgeons use the appearance of the foreskin or meatus to predict the diagnosis of LS. 1 Indeed, if the diagnosis of LS is made in childhood, does it change management in the long term? Pathological analysis of the excised foreskin is routinely done if there is suspicion of LS...
February 6, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Johan M Berghmans, Marten J Poley, Jan van der Ende, Andre Rietman, Inge Glazemakers, Dirk Himpe, Frank C Verhulst, Elisabeth Utens
BACKGROUND: Anesthesia and surgery may influence toddlers' sensory processing and consequently postoperative adjustment and behavior. This is the first study to: 1. test pre- to postoperative changes in sensory processing after pediatric anesthesia using the validated Infant/Toddler-Sensory Profile for 7-36 months (ITSP7-36); 2. identify putative predictors of these changes. METHODS: This prospective cohort study included 70 healthy boys (ASA I & II), aged 18- 30 months, who underwent circumcision for religious reasons...
February 5, 2018: Minerva Anestesiologica
Semiu E Folaranmi, Harriet J Corbett, Paul D Losty
PURPOSE: To determine whether treatment of lichen sclerosus et atrophicus (LS), with topical steroids reduces the rate of circumcision. METHODS: Two independent reviewers performed a literature search of studies reporting treatment of LS with topical steroids using EMBASE and MEDLINE database(s). INCLUSION CRITERIA: boys aged 0-18 years, clinical diagnosis of LS, treatment with topical steroids. Literature reviews, studies of phimosis without LS and adult patients were excluded...
January 3, 2018: Journal of Pediatric Surgery
Simnikiwe H Mayaphi, Desmond J Martin, Steve A S Olorunju, Brian G Williams, Thomas C Quinn, Anton C Stoltz
OBJECTIVE: To assess the prevalence of HIV risk behaviour among sexually active HIV sero-negative individuals in the Tshwane district of South Africa (SA). METHODS: Demographic and HIV risk behaviour data were collected on a questionnaire from participants of a cross-sectional study that screened for early HIV infection using pooled nucleic acid amplification testing (NAAT). The study enrolled individuals who tested negative on rapid HIV tests performed at five HIV counseling and testing (HCT) clinics, which included four antenatal clinics and one general HCT clinic...
2018: PloS One
Stephen W Pan, Richard M Carpiano, Dongliang Li, Zheng Zhang, Martin T Schechter, Patricia M Spittal, Yuhua Ruan
Ethnic affiliation can define sociocultural boundaries and contribute to the HIV vulnerabilities faced by men who have sex with men (MSM). This study investigated the influence of ethnic affiliation on HIV vulnerabilities among MSM in North China. Our study analyzed a cross-sectional survey of MSM (n = 398) in two major North China cities. We examined associations between ethnic affiliation and (a) HIV status, (b) sexual behaviors and experiences, and (c) substance use. Compared to ethnic majority Han MSM: MSM belonging to ethnic minority groups of South China had significantly greater odds of HIV infection (AOR: 7...
January 30, 2018: AIDS Care
Sumit Dave, Kourosh Afshar, Luis H Braga, Peter Anderson
No abstract text is available yet for this article.
December 1, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Sumit Dave, Kourosh Afshar, Luis H Braga, Peter Anderson
No abstract text is available yet for this article.
December 1, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Anna Löwa, Annika Vogt, Sabine Kaessmeyer, Sarah Hedtrich
Skin equivalents are increasingly used as human-based test systems for basic and preclinical research. Most of the established skin equivalents are composed of primary keratinocytes and fibroblasts, isolated either from excised human skin or juvenile foreskin following circumcisions. Although the potential of hair follicle-derived cells for the generation of skin equivalents has been shown, this approach normally requires microdissections from the scalp for which there is limitted subject compliance or ethical approval...
January 26, 2018: Journal of Tissue Engineering and Regenerative Medicine
L Zhao, H Yang, B R Ma, Z H Yin
Objectives: To evaluate the value of hysteroscopy in the diagnosis and treatment of cesarean scar pregnancy (CSP) incomplete abortion. Methods: A total of 42 patients with incomplete cesarean circumcision from January 2014 to March 2017 were retrospectively analyzed.Twenty-one patients underwent bilateral uterine artery embolization.Twenty patients underwent hysteroscopy Electrocardiose resection of pregnancy tissue and coagulation hemostasis, the control group of 22 patients underwent conventional uterine artery embolization surgery...
January 16, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Juan Va Franco, Tarek Turk, Jae Hung Jung, Yu-Tian Xiao, Stanislav Iakhno, Virginia Garrote, Valeria Vietto
BACKGROUND: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disorder in which the two main clinical features are pelvic pain and lower urinary tract symptoms. There are currently many approaches for its management, using both pharmacological and non-pharmacological interventions. The National Institute of Health - Chronic Prostatitis Symptom Index (NIH-CPSI) score is a validated measure commonly used to measure CP/CPPS symptoms. OBJECTIVES: To assess the effects of non-pharmacological therapies for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)...
January 26, 2018: Cochrane Database of Systematic Reviews
Juri Rabinovich
We report a case of a rare mesenchymal foreskin tumor. A slow-growing node was detected during the urological examination of a 39-year-old man. A histological examination following the node excision showed a superficial leiomyosarcoma. Superficial leiomyosarcomas rarely metastasize and are associated with a better prognosis than deeper tumors. The patient had no relapse 9 months after a successful radical circumcision. We strongly recommend a histological examination whenever a growing node in the genital area is found...
January 25, 2018: Der Urologe. Ausg. A
Seth Kalichman, Catherine Mathews, Moira Kalichman, Lisa A Eaton, Koena Nkoko
Medical male circumcision (MMC) is a proven method of HIV risk reduction for men in southern Africa. MMC promotion campaigns and scale-up programmes are widely implemented throughout the Republic of South Africa. However, the impact of promoting MMC on women's awareness, beliefs, and behaviours has been understudied. We conducted a self-administered anonymous survey of 279 women receiving health services in an impoverished township located in Cape Town, South Africa. Results showed that two in three women were unaware that male circumcision partially protects men from contracting HIV...
January 25, 2018: Global Public Health
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