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https://www.readbyqxmd.com/read/28441458/evidence-that-promotion-of-male-circumcision-did-not-lead-to-sexual-risk-compensation-in-prioritized-sub-saharan-countries
#1
Chyun-Fung Shi, Michael Li, Jonathan Dushoff
BACKGROUND: WHO and UNAIDS prioritized 14 eastern and southern African countries with high HIV and low male circumcision prevalence for a voluntary medical male circumcision (VMMC) scale-up in 2007. Because circumcision provides only partial protection against HIV infection to men, the issue of possible risk compensation in response to VMMC campaigns is of particular concern. In this study, we looked at population-level survey data from the countries prioritized by WHO for a VMMC scale-up...
2017: PloS One
https://www.readbyqxmd.com/read/28418491/educating-religious-leaders-increases-male-circumcision-rates-in-tanzania
#2
M J Friedrich
No abstract text is available yet for this article.
April 18, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28414783/acceptability-and-feasibility-of-early-infant-male-circumcision-for-hiv-prevention-in-malawi
#3
Charles Chilimampunga, Simeon Lijenje, Judith Sherman, Kelvin Nindi, Webster Mavhu
BACKGROUND: Voluntary medical male circumcision (VMMC) has been successfully implemented in 14 countries as an additional HIV prevention intervention. As VMMC programs mature in most countries, the focus is now on how to sustain the HIV prevention gains realised from VMMC. As part of preparations for the sustainability phase, countries are either piloting or preparing to pilot early infant male circumcision (EIMC). This qualitative study explored the acceptability and feasibility of EIMC in Malawi in order to inform pilot implementation...
2017: PloS One
https://www.readbyqxmd.com/read/28412847/circumcision-bleeding-complications-neonatal-intensive-care-infants-compared-to-those-in-the-normal-newborn-nursery
#4
Abigail R Litwiller, Courtney Browne, David M Haas
PURPOSE: To determine if a significant difference exists in the bleeding complications following circumcision in neonates admitted to neonatal intensive care unit (NICU) versus the normal newborn nursery (NNN). MATERIALS AND METHODS: Observational cohort study of 260 infants undergoing circumcision with Gomco clamp. Vitamin K was given to neonates at delivery. Demographic data, procedural characteristics, bleeding complications, and interventions were recorded. The bleeding rates of the two groups were compared using chi square...
April 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28406530/pseudoepitheliomatous-keratotic-and-micaceous-balanitis-treated-with-topical-5-fluorouracil-and-liquid-nitrogen
#5
K J L Choo, S K Ng, C S Sim, S W N Cheng
Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is an uncommon premalignant condition involving the glans penis. We report the case of an 86-year-old man who presented with phimosis and pain on retracting his foreskin. He had previously undergone circumcision, which revealed a hyperkeratotic plaque with thin mica-like scales involving his glans penis. Histology of the lesion showed hyperkeratosis, parakeratosis, epidermal acanthosis and papillomatosis with no evidence of dysplasia. Immunohistochemistry for human papillomavirus was negative...
April 13, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28406272/dorsal-longitudinal-foreskin-cut-is-associated-with-reduced-risk-of-hiv-syphilis-and-genital-herpes-in-men-a-cross-sectional-study-in-papua-new-guinea
#6
Andrew J Vallely, David MacLaren, Matthew David, Pamela Toliman, Angela Kelly-Hanku, Ben Toto, Rachael Tommbe, Zure Kombati, Petronia Kaima, Kelwyn Browne, Clement Manineng, Lalen Simeon, Claire Ryan, Handan Wand, Peter Hill, Greg Law, Peter M Siba, W John H McBride, John M Kaldor
INTRODUCTION: Various forms of penile foreskin cutting are practised in Papua New Guinea. In the context of an ecological association observed between HIV infection and the dorsal longitudinal foreskin cut, we undertook an investigation of this relationship at the individual level. METHODS: We conducted a cross-sectional study among men attending voluntary confidential HIV counselling and testing clinics. Following informed consent, participants had a face-to-face interview and an examination to categorize foreskin status...
April 3, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28406269/evaluating-the-feasibility-and-uptake-of-a-community-led-hiv-testing-and-multi-disease-health-campaign-in-rural-uganda
#7
REVIEW
(no author information available yet)
INTRODUCTION: Multi-disease community health campaigns can be effective for population-wide HIV testing in a research setting (SEARCH: NCT01864603). We sought to evaluate feasibility and uptake of a community-led health campaign (CLHC) planned and implemented by village leaders and local clinic workers in Uganda. METHODS: Over five months in 2014, locally elected village leaders and Ministry of Health (MoH) clinic staff in a rural parish in Uganda planned a census followed by a CLHC, after training by two SEARCH trial consultants and by leaders from a neighbouring parish that had previously participated in a SEARCH health campaign...
March 29, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28403211/the-potential-impact-and-cost-of-focusing-hiv-prevention-on-young-women-and-men-a-modeling-analysis-in-western-kenya
#8
Ramzi A Alsallaq, Jasmine Buttolph, Charles M Cleland, Timothy Hallett, Irene Inwani, Kawango Agot, Ann E Kurth
OBJECTIVE: We compared the impact and costs of HIV prevention strategies focusing on youth (15-24 year-old persons) versus on adults (15+ year-old persons), in a high-HIV burden context of a large generalized epidemic. DESIGN: Compartmental age-structured mathematical model of HIV transmission in Nyanza, Kenya. INTERVENTIONS: The interventions focused on youth were high coverage HIV testing (80% of youth), treatment at diagnosis (TasP, i.e...
2017: PloS One
https://www.readbyqxmd.com/read/28402442/risk-of-heterosexual-hiv-transmission-attributable-to-sexually-transmitted-infections-and-non-specific-genital-inflammation-in-zambian-discordant-couples-1994-2012
#9
Kristin M Wall, William Kilembe, Bellington Vwalika, Lisa B Haddad, Eric Hunter, Shabir Lakhi, Roy Chavuma, Naw Htee Khu, Ilene Brill, Cheswa Vwalika, Lawrence Mwananyanda, Elwyn Chomba, Joseph Mulenga, Amanda Tichacek, Susan Allen
Background: Studies have demonstrated the role of ulcerative and non-ulcerative sexually transmitted infections (STI) in HIV transmission/acquisition risk; less is understood about the role of non-specific inflammatory genital abnormalities. Methods: HIV-discordant heterosexual Zambian couples were enrolled into longitudinal follow-up (1994-2012). Multivariable models estimated the effect of genital ulcers and inflammation in both partners on time-to-HIV transmission within the couple...
April 11, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28393509/-an-unexpected-complication-glans-ischemia-after-circumcision-review-of-the-literature
#10
M Á Cárdenas Elías, F Vázquez Rueda, V Jiménez Crespo, A Siu Uribe, F J Murcia Pascual, J E Betancourth Alvarenga, R M Paredes Esteban
INTRODUCTION: Circumcision is a frequent and common surgical procedure in children; nevertheless it is not completely hassle-free. Post circumcision ischemic complications are even rare and they are generally due to administration of local vasoconstrictor anesthetics. There are few cases reported in the literature. We report the management and treatment of post- circumcision penile ischemia (PCI). CASE REPORT: A 10 years old patient who underwent circumcision and a dorsal penile nerve block DPNB presents signs of penile ischemia two hours after surgery without any other symptoms...
July 10, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/28389263/post-ritual-circumcision-bleeding-characteristics-and-treatment-outcome
#11
Roy Mano, Amihay Nevo, Bezalel Sivan, Roy Morag, David Ben-Meir
OBJECTIVE: To report the characteristics, treatment, and short term outcome of neonatal post-circumcision bleeding, and identify predictors of surgical treatment. METHODS: The medical records of 90 consecutive neonates who presented to the emergency room with post-circumcision bleeding between 2009 and 2014 were reviewed. Circumcisions were performed using the traditional Mogen shield device. The study endpoint was surgical intervention for hemostasis. Predictors of surgical treatment were evaluated...
April 4, 2017: Urology
https://www.readbyqxmd.com/read/28387902/angiogenesis-characteristics-of-infantile-hemangioma-and-feasibility-observation-of-transplantation-model-of-human-hemangioma-on-mice
#12
Y Fu, Z-G Yang, L-Y Zhao
OBJECTIVE: To study pathogenic features of pediatric hemangiomas, we successfully established a model in mice, by transplanting human hemangioma tissues. MATERIALS AND METHODS: The hemangioma from the leg of a two-month-old infant was dissected and sliced into several pieces. During a careful surgical procedure, the hemangioma tissues were individually transplanted into skin incisions in anesthetized mice. The volume of the transplanted tumors was measured and the changes in shape recorded at 1 day, and at 1, 2, 3, 4, 5 and 6 months after the transplantation...
March 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28382428/successful-management-of-zoon-s-balanitis-with-topical-mupirocin-ointment-a-case-report-and-literature-review-of-mupirocin-responsive-balanitis-circumscripta-plasmacelluaris
#13
REVIEW
Omar Bari, Philip R Cohen
INTRODUCTION: Zoon's balanitis, also referred to as balanitis circumscripta plasmacellularis (BCP), is an idiopathic, benign inflammatory condition of the glans penis and foreskin most often seen in elderly uncircumcised men. A patient with a biopsy-confirmed diagnosis of BCP who was successfully treated with topical mupirocin ointment is described. METHODS: The PubMed database was searched with the key words: bactroban, balanitis, cell, circumscripta, mupirocin, plasma, plasmacellularis, tacrolimus, Zoon...
April 5, 2017: Dermatology and Therapy
https://www.readbyqxmd.com/read/28377421/a-cross-sectional-analysis-of-trichomonas-vaginalis-infection-among-heterosexual-hiv-1-serodiscordant-african-couples
#14
Aaron F Bochner, Jared M Baeten, Alison S Rustagi, Edith Nakku-Joloba, Jairam R Lingappa, Nelly R Mugo, Elizabeth A Bukusi, Saidi Kapiga, Sinead Delany-Moretlwe, Connie Celum, Ruanne V Barnabas
OBJECTIVES: Trichomonas vaginalis is the most prevalent curable STI worldwide and has been associated with adverse health outcomes and increased HIV-1 transmission risk. We conducted a cross-sectional analysis among couples to assess how characteristics of both individuals in sexual partnerships are associated with the prevalence of male and female T. vaginalis infection. METHODS: African HIV-1 serodiscordant heterosexual couples were concurrently tested for trichomoniasis at enrolment into two clinical trials...
April 4, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28367749/improving-voluntary-medical-male-circumcision-standards-adherence-and-post-procedure-follow-up-in-uganda-a-mixed-methods-study
#15
Sarah Smith Lunsford, John Byabagambi, Zachariah Falconer-Stout, Esther Karamagi
Voluntary medical male circumcision (VMMC) has been demonstrated to reduce the transmission of HIV by 60%. Scaling up VMMC services requires that they be of high quality, socially accepted, and effective. We evaluated an intervention aimed at improving VMMC standards adherence and patient follow-up rates in nine facilities in Uganda. We also qualitatively explored why some men return for follow-up care and others do not. The completeness and quality of clinical documentation was poor at baseline, but significantly improved at endline...
March 2017: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/28365978/establishment-of-immortalized-primary-human-foreskin-keratinocytes-and-their-application-to-toxicity-assessment-and-three-dimensional-skin-culture-construction
#16
Moonju Choi, Minkyung Park, Suhyon Lee, Jeong Woo Lee, Min Chul Cho, Minsoo Noh, Choongho Lee
In spite of frequent usage of primary human foreskin keratinocytes (HFKs) in the study of skin biology, senescence-induced blockage of in vitro proliferation has been a big hurdle for their effective utilization. In order to overcome this passage limitation, we first isolated ten HFK lines from circumcision patients and successfully immortalized four of them via a retroviral transduction of high-risk human papillomavirus (HPV) E6 and E7 oncogenes. We confirmed expression of a keratinocyte marker protein, keratin 14 and two viral oncoproteins in these immortalized HFKs...
April 6, 2017: Biomolecules & Therapeutics
https://www.readbyqxmd.com/read/28365169/clinic-meatotomy-under-topical-anesthesia
#17
C M Fronczak, C A Villanueva
OBJECTIVES: Almost 20 years after Cartwright et al. (1996) demonstrated the feasibility and effectiveness of clinic meatotomy (CM) under topical lidocaine and prilocaine (EMLA) anesthesia, 50% of meatotomies are still performed under general anesthesia (GA) (Godley et al., 2015). The cost of a meatotomy under GA is approximately 10 times the cost of CM in the present practice. This study presented the outcomes for CM under topical anesthesia, in consecutive patients who presented with meatal stenosis secondary to circumcision...
March 15, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28364982/medical-male-circumcision-is-associated-with-improvements-in-pain-during-intercourse-and-sexual-satisfaction-in-kenya
#18
Monica P C Nordstrom, Nelli Westercamp, Walter Jaoko, Timothy Okeyo, Robert C Bailey
BACKGROUND: Two cohort studies using data from randomized controlled trials in Africa offer the best evidence to date on the effects of voluntary medical male circumcision (VMMC) on male sexual function and satisfaction, suggesting no significant impairments in sexual function or satisfaction and some improvements in sexual function after male circumcision. AIM: To assess the effects of VMMC on sexual function and satisfaction in a large population-based cohort of men circumcised as adults and uncircumcised controls in Kenya...
April 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28364568/spatial-patterns-of-hiv-prevalence-and-service-use-in-east-zimbabwe-implications-for-future-targeting-of-interventions
#19
Robin Schaefer, Simon Gregson, Albert Akaruza, Rebecca Rhead, Tidings Masoka, Nadine Schur, Sarah-Jane Anderson, Constance Nyamukapa
INTRODUCTION: Focusing resources for HIV control on geographic areas of greatest need in countries with generalized epidemics has been recommended to increase cost-effectiveness. However, socioeconomic inequalities between areas of high and low prevalence could raise equity concerns and have been largely overlooked. We describe spatial patterns in HIV prevalence in east Zimbabwe and test for inequalities in accessibility and uptake of HIV services prior to the introduction of spatially-targeted programmes...
February 27, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28362880/exploring-drivers-for-safe-male-circumcision-experiences-with-health-education-and-understanding-of-partial-hiv-protection-among-newly-circumcised-men-in-wakiso-uganda
#20
Simon P S Kibira, Marguerite Daniel, Lynn Muhimbuura Atuyambe, Fredrick Edward Makumbi, Ingvild Fossgard Sandøy
INTRODUCTION: About 2.5 million men have voluntarily been circumcised since Uganda started implementing the WHO recommendation to scale up safe male circumcision to reduce HIV transmission. This study sought to understand what influences men's circumcision decisions, their experiences with health education at health facilities and their knowledge of partial HIV risk reduction in Wakiso district. METHODS: Data were collected in May and June 2015 at five public health facilities in Wakiso District...
2017: PloS One
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