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https://www.readbyqxmd.com/read/27894575/pre-expanded-free-perforator-flaps
#1
REVIEW
Emre Hocaoğlu
Pre-expanded perforator flaps are the most recent technical way to shape tissue for exact needs. Reconstruction with pre-expanded free perforator flaps has proven successful in terms of obtaining more extensive, more pliable, and thinner flaps that have increased vascularity, and also causing less donor site morbidity. In this article the author's experience with the clinical application of such flaps and the relevant published literature are reviewed.
January 2017: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/27882997/development-of-a-validated-algorithm-for-the-diagnosis-of-paediatric-asthma-in-electronic-medical-records
#2
Andrew J Cave, Christina Davey, Elaheh Ahmadi, Neil Drummond, Sonia Fuentes, Seyyed Mohammad Reza Kazemi-Bajestani, Heather Sharpe, Matt Taylor
An accurate estimation of the prevalence of paediatric asthma in Alberta and elsewhere is hampered by uncertainty regarding disease definition and diagnosis. Electronic medical records (EMRs) provide a rich source of clinical data from primary-care practices that can be used in better understanding the occurrence of the disease. The Canadian Primary Care Sentinel Surveillance Network (CPCSSN) database includes cleaned data extracted from the EMRs of primary-care practitioners. The purpose of the study was to develop and validate a case definition of asthma in children 1-17 who consult family physicians, in order to provide primary-care estimates of childhood asthma in Alberta as accurately as possible...
November 24, 2016: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/27876569/o-space-with-high-resolution-readouts-outperforms-radial-imaging
#3
Haifeng Wang, Leo Tam, Emre Kopanoglu, Dana C Peters, R Todd Constable, Gigi Galiana
PURPOSE: While O-Space imaging is well known to accelerate image acquisition beyond traditional Cartesian sampling, its advantages compared to undersampled radial imaging, the linear trajectory most akin to O-Space imaging, have not been detailed. In addition, previous studies have focused on ultrafast imaging with very high acceleration factors and relatively low resolution. The purpose of this work is to directly compare O-Space and radial imaging in their potential to deliver highly undersampled images of high resolution and minimal artifacts, as needed for diagnostic applications...
November 20, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27874920/m%C3%A3-n-har-b%C3%A3-ttre-intensivv%C3%A3-rds%C3%A2-%C3%A3-verlevnad-%C3%A3-n-kvinnor-g%C3%A3-ller-fr%C3%A3-mst-diagnoser-som-hj%C3%A3-rtstopp-och-septisk-chock
#4
Hanna Nyberg, Carolina Samuelsson, Attila Frigyesi
Better intensive care outcomes for men than women especially in septic shock and after cardiac arrest In this study 11 764 intensive care admissions to Skåne University Hospital in Sweden between 2008 and 2015 were studied for any gender differences in outcome for different diagnoses. As known from previous studies, men had more intensive care admissions and had a higher morbidity necessitating the use of risk adjusted mortality measures. Through a simple but new application of VLAD we found this risk-adjusted mortality measure to be more sensitive in detecting differences in mortality between groups than the more commonly used SMR...
November 15, 2016: Läkartidningen
https://www.readbyqxmd.com/read/27842904/yield-of-computed-tomography-of-the-cervical-spine-in-cases-of-simple-assault
#5
Matthew L Uriell, Jason W Allen, Brendan P Lovasik, Marc D Benayoun, Robert M Spandorfer, Chad A Holder
BACKGROUND: Computed tomography (CT) of the cervical spine (C-spine) is routinely ordered for low-impact, non-penetrating or "simple" assault at our institution and others. Common clinical decision tools for C-spine imaging in the setting of trauma include the National Emergency X-Radiography Utilization Study (NEXUS) and the Canadian Cervical Spine Rule for Radiography (CCR). While NEXUS and CCR have served to decrease the amount of unnecessary imaging of the C-spine, overutilization of CT is still of concern...
October 29, 2016: Injury
https://www.readbyqxmd.com/read/27836816/web-based-real-time-case-finding-for-the-population-health-management-of-patients-with-diabetes-mellitus-a-prospective-validation-of-the-natural-language-processing-based-algorithm-with-statewide-electronic-medical-records
#6
Le Zheng, Yue Wang, Shiying Hao, Andrew Y Shin, Bo Jin, Anh D Ngo, Medina S Jackson-Browne, Daniel J Feller, Tianyun Fu, Karena Zhang, Xin Zhou, Chunqing Zhu, Dorothy Dai, Yunxian Yu, Gang Zheng, Yu-Ming Li, Doff B McElhinney, Devore S Culver, Shaun T Alfreds, Frank Stearns, Karl G Sylvester, Eric Widen, Xuefeng Bruce Ling
BACKGROUND: Diabetes case finding based on structured medical records does not fully identify diabetic patients whose medical histories related to diabetes are available in the form of free text. Manual chart reviews have been used but involve high labor costs and long latency. OBJECTIVE: This study developed and tested a Web-based diabetes case finding algorithm using both structured and unstructured electronic medical records (EMRs). METHODS: This study was based on the health information exchange (HIE) EMR database that covers almost all health facilities in the state of Maine, United States...
November 11, 2016: JMIR Medical Informatics
https://www.readbyqxmd.com/read/27818188/complete-spinal-cord-injury-sci-transforms-how-brain-derived-neurotrophic-factor-bdnf-affects-nociceptive-sensitization
#7
Yung-Jen Huang, Kuan H Lee, James W Grau
Noxious stimulation can induce a lasting increase in neural excitability within the spinal cord (central sensitization) that can promote pain and disrupt adaptive function (maladaptive plasticity). Brain-derived neurotrophic factor (BDNF) is known to regulate the development of plasticity and has been shown to impact the development of spinally-mediated central sensitization. The latter effect has been linked to an alteration in GABA-dependent inhibition. Prior studies have shown that, in spinally transected rats, exposure to regular (fixed spaced) stimulation can counter the development of maladaptive plasticity and have linked this effect to an up-regulation of BDNF...
November 3, 2016: Experimental Neurology
https://www.readbyqxmd.com/read/27805795/piloting-electronic-medical-record-based-early-detection-of-inpatient-deterioration-in-community-hospitals
#8
Gabriel J Escobar, Benjamin J Turk, Arona Ragins, Jason Ha, Brian Hoberman, Steven M LeVine, Manuel A Ballesca, Vincent Liu, Patricia Kipnis
Patients who deteriorate in the hospital outside the intensive care unit (ICU) have higher mortality and morbidity than those admitted directly to the ICU. As more hospitals deploy comprehensive inpatient electronic medical records (EMRs), attempts to support rapid response teams with automated early detection systems are becoming more frequent. We aimed to describe some of the technical and operational challenges involved in the deployment of an early detection system. This 2-hospital pilot, set within an integrated healthcare delivery system with 21 hospitals, had 2 objectives...
November 2016: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/27801410/-the-ultrastructure-of-leydig-cells-under-the-influence-of-drinking-mineral-water-and-electromagnetic-radiation-under-the-stress-conditions-in-the-rats
#9
M S Geniatulina, Yu N Korolev, L A Nikulina
The objective of the present study was elucidate the peculiar features of low-intensity electromagnetic radiation (LI EMR) and mineral water (MW) on the ultrastructure of rat Leydig cells under conditions of immobilization stress. The experiments were carried out on outbred male rats with the use of electron microscopy. It has been demonstrated that the prophylactic consumption of drinking sulfate-containing mineral water and the application low-intensity electromagnetic radiation (with the flow power density of 1 mcW/cm2 and frequency around 1,000 Hz) or the combination of these two modalities under conditions of immobilization stress reduced the degree of ultrastructural derangement in the rat Leydig cells and stimulated the development of regenerative processes...
2016: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/27792870/phenome-wide-association-study-of-autoantibodies-to-citrullinated-and-non-citrullinated-epitopes-in-rheumatoid-arthritis
#10
Katherine P Liao, Jeffrey A Sparks, Boris P Hejblum, I-Hsin Kuo, Jing Cui, Lauren J Lahey, Andrew Cagan, Vivian S Gainer, Weidong Liu, T Tony Cai, Jeremy Sokolove, Tianxi Cai
OBJECTIVE: RA patients develop autoantibodies against a spectrum of antigens but their clinical significance is unclear. Using the phenome-wide association study (PheWAS) approach, we examined the association between autoantibodies and clinical subphenotypes of RA. METHODS: This study was conducted using a validated electronic medical record (EMR) RA cohort from 2 tertiary care centers. Using a published multiplex bead assay, we measured 36 autoantibodies targeting epitopes implicated in RA...
October 28, 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/27783315/image-cloud-medical-image-processing-as-a-service-for-regional-healthcare-in-a-hybrid-cloud-environment
#11
Li Liu, Weiping Chen, Min Nie, Fengjuan Zhang, Yu Wang, Ailing He, Xiaonan Wang, Gen Yan
OBJECTIVES: To handle the emergence of the regional healthcare ecosystem, physicians and surgeons in various departments and healthcare institutions must process medical images securely, conveniently, and efficiently, and must integrate them with electronic medical records (EMRs). In this manuscript, we propose a software as a service (SaaS) cloud called the iMAGE cloud. METHODS: A three-layer hybrid cloud was created to provide medical image processing services in the smart city of Wuxi, China, in April 2015...
November 2016: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/27757179/factors-influencing-the-adoption-of-health-information-technologies-a-systematic-review
#12
Ali Garavand, Mohammah Mohseni, Heshmatollah Asadi, Manal Etemadi, Mohammad Moradi-Joo, Ahmad Moosavi
INTRODUCTION: The successful implementation of health information technologies requires investigating the factors affecting the acceptance and use of them. The aim of this study was to determine the most important factors affecting the adoption of health information technologies by doing a systematic review on the factors affecting the acceptance of health information technology. METHODS: This systematic review was conducted by searching the major databases, such as Google Scholar, Emerald, Science Direct, Web of Science, Pubmed, and Scopus...
August 2016: Electronic Physician
https://www.readbyqxmd.com/read/27733925/code-generator-for-implementing-dual-tree-complex-wavelet-transform-on-reconfigurable-architectures-for-mobile-applications
#13
Ferhat Canbay, Vecdi Emre Levent, Gorkem Serbes, H Fatih Ugurdag, Sezer Goren, Nizamettin Aydin
The authors aimed to develop an application for producing different architectures to implement dual tree complex wavelet transform (DTCWT) having near shift-invariance property. To obtain a low-cost and portable solution for implementing the DTCWT in multi-channel real-time applications, various embedded-system approaches are realised. For comparison, the DTCWT was implemented in C language on a personal computer and on a PIC microcontroller. However, in the former approach portability and in the latter desired speed performance properties cannot be achieved...
September 2016: Healthcare Technology Letters
https://www.readbyqxmd.com/read/27721251/application-value-of-endoscopic-submucosal-dissection-and-endoscopic-mucosal-resection-for-treatment-of-rectal-carcinoids
#14
Xiaohuan Li, Yongxian Gui, Wenliang Han, Hongjian Jiang, Daihua Qi, Yi Yang
OBJECTIVE: The objective of this study is to explore the clinical effect and safety of endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) for treatment of rectal carcinoids. METHODS: A retrospective analysis was conducted on 42 patients with rectal carcinoids who were hospitalized and subjected to surgical treatment in our hospital from January 2010 to November 2015. The patients were categorized into two groups based on treatment received: ESD (n = 22) and EMR (n = 20)...
October 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/27712714/development-and-validation-of-algorithms-to-identify-statin-intolerance-in-a-us-administrative-database
#15
Kathy L Schulman, Lois E Lamerato, Mehul R Dalal, Jennifer Sung, Mehul Jhaveri, Andrew Koren, Usha G Mallya, JoAnne M Foody
OBJECTIVES: To develop and validate algorithms to define statin intolerance (SI) in an administrative database using electronic medical records (EMRs) as the reference comparison. METHODS: One thousand adults with one or more qualifying changes in statin therapy and one or more previous diagnoses of hyperlipidemia, hypercholesterolemia, or mixed dyslipidemia were identified from the Henry Ford Health System administrative database. Data regarding statin utilization, comorbidities, and adverse effects were extracted from the administrative database and corresponding EMR...
September 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27686316/alveoler-process-fracture-in-mandibular-immature-permanent-incisors-region
#16
Tamer Tuzuner, Gorkem Yahyaoglu, Emre Tosun, Fatih Taskesen, Adem Kusgoz
The presented case evaluates the treatment of an alveolar fracture associated with mandibular immature lower permanent incisors. An 8-year-old girl was referred to our clinic 3 hours after the trauma. The clinical and radiographic examination of the alveoler bone showed a fracture, along with the mandibular fracture and significant segment mobility and dislocation of several immature mandibular permanent incisors. These were moving together to the lingual side because of the direct trauma associated with falling from the school wall...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27671513/the-immunostimulatory-effect-of-lactic-acid-bacteria-in-a-rat-model
#17
Murat Karamese, Hakan Aydin, Emin Sengul, Volkan Gelen, Cigdem Sevim, Duran Ustek, Emre Karakus
BACKGROUND: Probiotics are "live", beneficial microbes that provide important health benefits in their hosts. There is significant interest in the modulation and regulation of the immune function by probiotics. OBJECTIVE: To investigate the immunomodulatory effects of a probiotic mixture, including Lactobacillus and Bifidobacterium species, by detecting serum cytokine and immunoglobulin levels. METHODS: The rats were randomly divided into 4 groups...
September 2016: Iranian Journal of Immunology: IJI
https://www.readbyqxmd.com/read/27651940/hospital-information-systems-experience-at-the-fully-digitized-seoul-national-university-bundang-hospital
#18
REVIEW
Sooyoung Yoo, Hee Hwang, Sanghoon Jheon
The different levels of health information technology (IT) adoption and its integration into hospital workflow can affect the maximization of the benefits of using of health IT. We aimed at sharing our experiences and the journey to the successful adoption of health IT over 13 years at a tertiary university hospital in South Korea. The integrated system of comprehensive applications for direct care, support care, and smart care has been implemented with the latest IT and a rich user information platform, achieving the fully digitized hospital...
August 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27651721/the-relationship-between-first-trimester-pregnancy-associated-plasma-protein-a-levels-and-intrapartum-fetal-distress-development
#19
Ayşe Filiz Avşar, Elçin İşlek Seçen, Gülin Feykan Yeğin Akçay, Hüseyin Levent Keskin, Emre Erdem Taş, Ahmet Ferit Dalgacı
OBJECTIVE: To investigate the relationship between the development of intrapartum fetal distress and serum pregnancy-associated plasma protein-A (PAPP-A) levels measured during first-trimester aneuploidy screening tests. MATERIAL AND METHODS: This retrospective study included 283 uncomplicated pregnancies that resulted in full-term live births via spontaneous labor or with the induction by oxytocin. Cases were divided into two groups based on whether their first-trimester PAPP-A multiple of the median (MoM) levels were ≤0...
2016: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/27639636/acute-spinal-cord-injury-sci-transforms-how-gaba-affects-nociceptive-sensitization
#20
Yung-Jen Huang, Kuan H Lee, Lauren Murphy, Sandra M Garraway, James W Grau
Noxious input can sensitize pain (nociceptive) circuits within the spinal cord, inducing a lasting increase in spinal cord neural excitability (central sensitization) that is thought to contribute to chronic pain. The development of spinally-mediated central sensitization is regulated by descending fibers and GABAergic interneurons. The current study provides evidence that spinal cord injury (SCI) transforms how GABA affects nociceptive transmission within the spinal cord, recapitulating an earlier developmental state wherein GABA has an excitatory effect...
November 2016: Experimental Neurology
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