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https://www.readbyqxmd.com/read/28230589/effects-of-local-and-systemic-zoledronic-acid-application-on-titanium-implant-osseointegration-an-experimental-study-conducted-on-two-surface-types
#1
Serkan Dundar, Ferhan Yaman, Orhan Gecor, Omer Cakmak, Mustafa Kirtay, Tuba Talo Yildirim, Tahir Karaman, Mehmet Emre Benlidayi
The aim of this study was to evaluate the effects of local and systemic zoledronic acid (ZA) applications on titaniumoksit ceramic blasted (TiO-CB)- and sandblasted large acid-grit (SLA)-surfaced titanium implant osseointegration. Twelve New Zealand White rabbits were used in the study, divided into 6 groups: the TiO-CB (TiO-CB-CNT) (n = 2) and SLA (SLA-CNT) (n = 2) control groups in which TiO-CB- and SLA-surfaced titanium implants were surgically inserted into rabbit tibias but no treatment was applied; the TiO-CB (TiO-CB-LZA) (n = 2) and SLA (SLA-LZA) (n = 2) local ZA groups in which 1 mL of normal saline solution containing 2 mg of ZA was injected into sockets and after this the implants were integrated; and the TiO-CB (TiO-CB-SZA) (n = 2) and SLA (SLA-SZA) (n = 2) systemic ZA groups in which a single infusion of 0...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28230047/electrically-tunable-artificial-gauge-potential-for-polaritons
#2
Hyang-Tag Lim, Emre Togan, Martin Kroner, Javier Miguel-Sanchez, Atac Imamoğlu
Neutral particles subject to artificial gauge potentials can behave as charged particles in magnetic fields. This fascinating premise has led to demonstrations of one-way waveguides, topologically protected edge states and Landau levels for photons. In ultracold neutral atoms, effective gauge fields have allowed the emulation of matter under strong magnetic fields leading to realization of Harper-Hofstadter and Haldane models. Here we show that application of perpendicular electric and magnetic fields effects a tunable artificial gauge potential for two-dimensional microcavity exciton polaritons...
February 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28227143/csdc-a-nationwide-screening-platform-for-stroke-control-and-prevention-in-china
#3
Jinghui Yu, Huajian Mao, Mei Li, Dan Ye, Dongsheng Zhao, Jinghui Yu, Huajian Mao, Mei Li, Dan Ye, Dongsheng Zhao, Dan Ye, Huajian Mao, Mei Li, Dongsheng Zhao, Jinghui Yu
As a leading cause of severe disability and death, stroke places an enormous burden on Chinese society. A nationwide stroke screening platform called CSDC (China Stoke Data Center) has been built to support the national stroke prevention program and stroke clinical research since 2011. This platform is composed of a data integration system and a big data analysis system. The data integration system is used to collect information on risk factors, diagnosis history, treatment, and sociodemographic characteristics and stroke patients' EMR...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227053/the-effects-of-deep-network-topology-on-mortality-prediction
#4
Hao Du, Mohammad M Ghassemi, Mengling Feng, Hao Du, Mohammad M Ghassemi, Mengling Feng, Mengling Feng, Hao Du, Mohammad M Ghassemi
Deep learning has achieved remarkable results in the areas of computer vision, speech recognition, natural language processing and most recently, even playing Go. The application of deep-learning to problems in healthcare, however, has gained attention only in recent years, and it's ultimate place at the bedside remains a topic of skeptical discussion. While there is a growing academic interest in the application of Machine Learning (ML) techniques to clinical problems, many in the clinical community see little incentive to upgrade from simpler methods, such as logistic regression, to deep learning...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227019/prediction-using-patient-comparison-vs-modeling-a-case-study-for-mortality-prediction
#5
Mark Hoogendoorn, Ali El Hassouni, Kwongyen Mok, Marzyeh Ghassemi, Peter Szolovits, Mark Hoogendoorn, Ali El Hassouni, Kwongyen Mok, Marzyeh Ghassemi, Peter Szolovits, Kwongyen Mok, Ali El Hassouni, Peter Szolovits, Marzyeh Ghassemi, Mark Hoogendoorn
Information in Electronic Medical Records (EMRs) can be used to generate accurate predictions for the occurrence of a variety of health states, which can contribute to more pro-active interventions. The very nature of EMRs does make the application of off-the-shelf machine learning techniques difficult. In this paper, we study two approaches to making predictions that have hardly been compared in the past: (1) extracting high-level (temporal) features from EMRs and building a predictive model, and (2) defining a patient similarity metric and predicting based on the outcome observed for similar patients...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28194453/a-paper-based-platform-for-detection-of-viral-rna
#6
Daohong Zhang, David Broyles, Eric A Hunt, Emre Dikici, Sylvia Daunert, Sapna K Deo
Viral detection presents a host of challenges for even the most sensitive analytical techniques, and the complexity of common detection platforms typically preclude portability. With these considerations in mind, we designed a paper microzone plate-based virus detection system for the detection of viral genetic material that can be performed with simple instruments. The sensing system can detect viral cDNA reverse-transcribed from total RNA extraction by utilizing a biotinylated capture probe and an Alexa Fluor® 647-labeled reporter probe...
February 14, 2017: Analyst
https://www.readbyqxmd.com/read/28186767/size-control-of-silver-core-silica-shell-nanoparticles-fabricated-by-laser-ablation-assisted-chemical-reduction
#7
Victor A Ermakov, Ernesto Jimenez-Villar, José Maria Clemente da Silva Filho, Emre Yassitepe, Naga Vishnu Vardhan Mogili, Fernando Iikawa, Gilberto Fernandes de Sá, Carlos Lenz Cesar, Francisco Chagas Marques
Aqueous colloidal silver nanoparticles have substantial potential in biological application as markers and antibacterial agents and in surface-enhanced Raman spectroscopy applications. A simple method of fabrication and encapsulation into an inert shell is of great importance today to make their use ubiquitous. Here we show that colloids of silver-core/silica-shell nanoparticles can be easily fabricated by a laser-ablation-assisted chemical reduction method and their sizes can be tuned in the range of 2.5 to 6...
February 20, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28181438/zero-dimensional-cs4pbbr6-perovskite-nanocrystals
#8
Yuhai Zhang, Makhsud I Saidaminov, Ibrahim Dursun, Haoze Yang, Banavoth Murali, Erkki Alarousu, Emre Yengel, Buthainah A Alshankiti, Osman M Bakr, Omar F Mohammed
Perovskite nanocrystals (NCs) have become leading candidates for solution-processed optoelectronics applications. While substantial work has been published on 3-D perovskite phases, the NC form of zero-dimensional (0-D) phase of this promising class of materials remains elusive. Here, we report the synthesis of a new class of colloidal semiconductors NCs based on Cs4PbBr6 - the zero-dimensional perovskite- enabled through the design of a novel low-temperature reverse microemulsion method with 85 % reaction yield...
February 9, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28177227/molecular-structure-of-canonical-liquid-crystal-interfaces
#9
Monirosadat Sadati, Hadi Ramezani-Dakhel, Wei Bu, Emre Sevgen, Zhu Liang, Cem Erol, Mohammad Rahimi, Nader Taheri Qazvini, Binhua Lin, Nicholas L Abbott, Benoit Roux, Mark L Schlossman, Juan J de Pablo
Numerous applications of liquid crystals (LC) rely on control of molecular orientation at an interface. However, little is known about the precise molecular structure of such interfaces. In this work, synchrotron X-ray reflectivity measurements, accompanied by large-scale atomistic molecular dynamics simulations, are used for the first time to reconstruct the air-liquid crystal interface of a nematic material, namely 5CB (4-Pentyl-4'-Cyanobiphenyl). The results are compared to those for 8CB (4-Octyl-4'-Cyanobiphenyl) which, in addition to isotropic and nematic states, can also form a smectic phase...
February 8, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28152756/making-steps-to-decrease-emergency-room-visits-in-patients-with-cancer-our-experience-after-participating-in-the-asco-quality-training-program
#10
Alvaro Jose Alencar, Aurelio Bartolome Castrellon, Luis E Raez, Vedner Guerrier
: 51 Background: Overutilization of emergency room services by oncology patients is a known problem associated with increased admission rates and health care expenditure. A review of our oncology patients' emergency room (ER) visits from January to May 2015 demonstrated that 48% of ER visits happened during office hours. Consequently a rapid cycle quality improvement project was developed with an aim to decrease ER visits by 30% by September 2015. METHODS: A multidisciplinary team completed an action plan, starting with a project charter and definition of aim statement...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28149801/bupivacaine-application-reduces-post-thyroidectomy-pain-cerrahpasa-experience
#11
Serkan Teksoz, Akif Enes Arikan, Selen Soylu, Safak Emre Erbabacan, Murat Ozcan, Yusuf Bukey
BACKGROUND: We aimed to evaluate the impact of bupivacaine administration into the surgical field after total thyroidectomy on post-operative pain and analgesic requirement with a double-blind, prospective, clinical and randomized study. METHODS: The study was performed between 2010 and 2011. Pain assessment was performed with the visual analog score (VAS). Patients were pre-operatively, randomly divided into two groups to receive either bupivacaine or saline. One group received a 10-mL of bupivacaine solution while the other group was treated with the same volume of 0...
December 2016: Gland Surgery
https://www.readbyqxmd.com/read/28145714/double-charged-surface-layers-in-lead-halide-perovskite-crystals
#12
Smritakshi Phukan Sarmah, Victor Burlakov, Emre Yengel, Banavoth Murali, Erkki Alarousu, Ahmed M El-Zohry, Chen Yang, Mohd Sharizal Alias, Ayan A Zhumekenov, Makhsud I Saidaminov, Namchul Cho, Nimer Wehbe, Somak Mitra, Idris A Ajia, Sukumar Dey, Ahmed E Esam Mansour, Maged Abdelsamie, Aram Amassian, Iman S Roqan, Boon S Ooi, Alain Goriely, Osman M Bakr, Omar F Mohammed
Understanding defect chemistry, particularly ion migration, and its significant effect on the surface's optical and electronic properties is one of the major challenges impeding the development of hybrid perovskite-based devices. Here, using both experimental and theoretical approaches, we demonstrated that the surface layers of the perovskite crystals may acquire a high concentration of positively charged vacancies with the complementary negatively charged halide ions pushed to the surface. This charge separation near the surface generates an electric field that can induce an increase of optical band gap in the surface layers relative to the bulk...
February 1, 2017: Nano Letters
https://www.readbyqxmd.com/read/28134555/development-and-applications-of-the-veterans-health-administration-s-stratification-tool-for-opioid-risk-mitigation-storm-to-improve-opioid-safety-and-prevent-overdose-and-suicide
#13
Elizabeth M Oliva, Thomas Bowe, Sara Tavakoli, Susana Martins, Eleanor T Lewis, Meenah Paik, Ilse Wiechers, Patricia Henderson, Michael Harvey, Tigran Avoundjian, Amanuel Medhanie, Jodie A Trafton
Concerns about opioid-related adverse events, including overdose, prompted the Veterans Health Administration (VHA) to launch an Opioid Safety Initiative and Overdose Education and Naloxone Distribution program. To mitigate risks associated with opioid prescribing, a holistic approach that takes into consideration both risk factors (e.g., dose, substance use disorders) and risk mitigation interventions (e.g., urine drug screening, psychosocial treatment) is needed. This article describes the Stratification Tool for Opioid Risk Mitigation (STORM), a tool developed in VHA that reflects this holistic approach and facilitates patient identification and monitoring...
February 2017: Psychological Services
https://www.readbyqxmd.com/read/28111654/dual-pathway-chain-end-modification-of-raft-polymers-using-visible-light-and-metal-free-conditions
#14
Emre H Discekici, Shelby L Shankel, Athina Anastasaki, Bernd Oschmann, In-Hwan Lee, Jia Niu, Alaina J McGrath, Paul G Clark, David S Laitar, Javier Read de Alaniz, Craig J Hawker, David J Lunn
We report a metal-free strategy for the chain-end modification of RAFT polymers utilizing visible light. By turning the light source on or off, the reaction pathway in one pot can be switched between either complete desulfurization (hydrogen chain-end) or simple cleavage (thiol chain-end), respectively. The versatility of this process is exemplified by application to a wide range of polymer backbones under mild, quantitative conditions using commercial reagents.
February 2, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28108349/expression-of-a-soluble-truncated-vargula-luciferase-in-escherichia-coli
#15
Eric A Hunt, Angeliki Moutsiopoulou, David Broyles, Trajen Head, Emre Dikici, Sylvia Daunert, Sapna K Deo
Marine luciferases are regularly employed as useful reporter molecules across a range of various applications. However, attempts to transition expression from their native eukaryotic environment into a more economical prokaryotic, i.e. bacterial, expression system often presents several challenges. Specifically, bacterial protein expression inherently lacks chaperone proteins to aid in the folding process, while Escherichia coli presents a reducing cytoplasmic environment in. These conditions contribute to the inhibition of proper folding of cysteine-rich proteins, leading to incorrect tertiary structure and ultimately inactive and potentially insoluble protein...
January 18, 2017: Protein Expression and Purification
https://www.readbyqxmd.com/read/28078665/computerized-pharmacy-surveillance-and-alert-system-for-drug-related-problems
#16
O Ferrández, O Urbina, S Grau, J Mateu-de-Antonio, M Marin-Casino, J Portabella, S Mojal, M Riu, E Salas
WHAT IS KNOWN AND OBJECTIVE: Because of the impact of drug-related problems (DRPs) on morbidity and mortality, there is a need for computerized strategies to increase drug safety. The detection and identification of the causes of potential DRPs can be facilitated by the incorporation of a pharmacy warning system (PWS) in the computerized prescriber order entry (CPOE) and its application in the routine validation of inpatient drug therapy. A limited number of studies have evaluated a clinical decision support system to monitor drug treatment...
January 12, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28077885/designing-and-implementation-of-retina-image-drawing-system-and-automatic-report-generation-from-retina-examinations
#17
Reza Safdari, Mehrshad Mokhtaran, Shahram Tahmasebian
INTRODUCTION: Electronic medical records as one of major parts of electronic health records is an important application of Medical Informatics. EMR includes different types of data, Graphical items being one of these data types. To this end, a standard structure for storing and recovering and finally exchanging this data type is required. In order to standardize information items in this research, UMLS standard is used. In this research, graphical information from fondues designing in retina surgery forms is used for the task of implementation...
October 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28074456/therapeutic-efficacy-of-tadalafil-and-eriythropoietin-in-experimental-spinal-cord-injury
#18
Çağrı Kökoğlu, Emre Delen, Ali Arslantaş, Didem Arslantaş, Burcu Kökoğlu, Zühtü Özbek, Sema Uslu, Ahmet Tolgay Akıncı
BACKGROUND: This experimental study was an investigation of the efficacy of erythropoietin and tadalafil in rats with induced spinal cord injury (SCI). METHODS: Thirty-five Sprague Dawley rats were distributed into 5 groups. First group was used for normal biochemical values. Spinal cord injury was induced in 4 remaining groups with clip compression technique after laminectomy process to T10 vertebra. Second group was designated solvent group and received 1 cc physiological serum after injury...
November 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28063462/going-digital-a-narrative-overview-of-the-clinical-and-organisational-impacts-of-ehealth-technologies-in-hospital-practice
#19
Justin Keasberry, Ian A Scott, Clair Sullivan, Andrew Staib, Richard Ashby
Objective The aim of the present study was to determine the effects of hospital-based eHealth technologies on quality, safety and efficiency of care and clinical outcomes.Methods Systematic reviews and reviews of systematic reviews of eHealth technologies published in PubMed/Medline/Cochrane Library between January 2010 and October 2015 were evaluated. Reviews of implementation issues, non-hospital settings or remote care or patient-focused technologies were excluded from analysis. Methodological quality was assessed using a validated appraisal tool...
January 9, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/28060844/where-s-your-phone-a-survey-of-where-women-aged-15-40-carry-their-smartphone-and-related-risk-perception-a-survey-and-pilot-study
#20
Mary Redmayne
Smartphones are now owned by most young adults in many countries. Installed applications regularly update while the phone is in standby. If it is kept near the body, this can lead to considerably higher exposure to radiofrequency electromagnetic radiation than occurred without internet access. Very little is known about current smartphone carrying habits of young women. This survey used an online questionnaire to ask about smartphone location under several circumstances to inform the power calculation for a women's health study...
2017: PloS One
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