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EMR applications

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https://www.readbyqxmd.com/read/28736771/on-interestingness-measures-for-mining-statistically-significant-and-novel-clinical-associations-from-emrs
#1
Orhan Abar, Richard J Charnigo, Abner Rayapati, Ramakanth Kavuluru
Association rule mining has received significant attention from both the data mining and machine learning communities. While data mining researchers focus more on designing efficient algorithms to mine rules from large datasets, the learning community has explored applications of rule mining to classification. A major problem with rule mining algorithms is the explosion of rules even for moderate sized datasets making it very difficult for end users to identify both statistically significant and potentially novel rules that could lead to interesting new insights and hypotheses...
October 2016: ACM-BCB: ACM Conference on Bioinformatics, Computational Biology and Biomedicine
https://www.readbyqxmd.com/read/28720474/nitrous-oxide-cryotherapy-for-treatment-of-esophageal-squamous-cell-neoplasia-initial-multicenter-international-experience-with-a-novel-portable-cryoballoon-ablation-system-with-video
#2
Marcia Irene Canto, Julian Abrams, Hannah Kunzli, Bas Weusten, Yoshihiro Komatsu, Blair Jobe, Charles J Lightdale
BACKGROUND AND AIMS: Early esophageal squamous cell neoplasia (ESCN) can be successfully treated by endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), or radiofrequency ablation (RFA). A new portable, battery-powered cryotherapy system using nitrous oxide (cryoballoon focal ablation system (CbFAS) has been used for Barrett's esophagus. It consists of a small hand-held device containing liquid nitrous oxide, which converts to gas within a low-pressure-compliant through-the-scope balloon and freezes targeted mucosa in contact with the balloon...
July 15, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28707620/a-quechers-based-sample-preparation-method-for-the-analysis-of-5-nitroimidazoles-in-bovine-milk-by-hplc-dad
#3
Tomasz Tuzimski, Tomasz Rejczak
In this study, a simple, cost-effective, and sensitive HPLC diode-array detection method was developed for thesimultaneous determination of six different 5-nitroimidazoles [metronidazole, 2-hydroxymethyl-1-methyl-5-nitro-(1)H-imidazole, dimetridazole (DMZ), ronidazole, ornidazole, and ipronidazole] in bovine milk samples. A QuEChERS-based sample preparation procedure was optimized by evaluating different cleanup sorbents, including zirconium-based sorbents (Z-Sep and Z-Sep+), C18, and primary–secondary amine (PSA), as well as EMR-Lipid cleanup solution...
July 13, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28684347/the-adult-deformity-surgery-complexity-index-adsci-a-valid-tool-to-quantify-the-complexity-of-posterior-adult-spinal-deformity-surgery-and-predict-postoperative-complications
#4
Ferran Pellisé, Alba Vila-Casademunt, Susana Núñez-Pereira, Montse Domingo-Sàbat, Juan Bagó, Xavier Vidal, Ahmet Alanay, Emre Acaroglu, Frank Kleinstück, Ibrahim Obeid, Francisco J S Pérez-Grueso, Virginie Lafage, Shay Bess, Christopher Ames, Anne F Mannion
BACKGROUND CONTEXT: In 2008, Mirza et al. designed and validated the first and only index capable of quantifying the complexity of spine surgery. However, this index is not fully applicable to adult spinal deformity (ASD) surgery, since it does not include the surgical techniques most commonly used and most strongly associated with perioperative complications in ASD patients. PURPOSE: The objective of this study is to develop an "Adult Deformity Surgery Complexity Index" (ADSCI), to quantify objectively the complexity of the ASD posterior surgery...
July 3, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28651625/iopromide-and-gadopentetic-acid-derived-preparates-used-in-mr-arthrography-may-be-harmful-to-chondrocytes
#5
Kadir Oznam, Duygu Yasar Sirin, Ibrahim Yilmaz, Yasin Emre Kaya, Mehmet Isyar, Seyit Ali Gumustas, Hanefi Ozbek, Semih Akkaya, Arda Kayhan, Mahir Mahirogullari
BACKGROUND: Magnetic resonance arthrography, a procedure through which contrast agents containing gadolinium and/or iopromide are administered intra-articularly, has become a useful tool in musculoskeletal diagnosis. Nevertheless, despite being considered safe for systemic use, certain tissue toxicities have been identified for both drugs. In this study, the effects of short-term exposure of human primary chondrocyte cell cultures to gadolinium and/or iopromide contrast agents were examined by assaying for stage-specific embryonic antigen-1 (SSEA-1) protein expression (a chondrogenic differentiation marker), cell viability, toxicity, and proliferation...
June 26, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28616600/minimally-invasive-surgery-for-gastric-cancer-in-uk-current-status-and-future-perspectives
#6
REVIEW
Muhammad Shafique Sajid, Madhusoodhana Hebbar, Mazin E Sayegh
The aim of this study is to review the literature and report the various minimally invasive methods used to treat gastric cancer in the UK and compare it with worldwide practice. Published randomised studies, non-randomised studies and case series reporting the use of minimal invasive approach to treat gastric cancer were retrieved from the search of standard medical electronic databases and their outcomes were highlighted suggesting their effectiveness. Several randomised, controlled trials and meta-analyses have proven the clinical and oncological safety of the laparoscopic gastrectomy for gastric cancer...
2017: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28605119/aromatherapy-massage-for-neuropathic-pain-and-quality-of-life-in-diabetic-patients
#7
Zehra Gok Metin, Ayse Arikan Donmez, Nur Izgu, Leyla Ozdemir, Ismail Emre Arslan
PURPOSE: This study aimed to examine the effects of aromatherapy massage on neuropathic pain severity and quality of life (QoL) in patients suffering from painful diabetic neuropathy. DESIGN AND METHODS: This open-label randomized controlled clinical study was conducted in a university hospital endocrine outpatient clinic in Turkey. The study sample consisted of 46 patients, randomly allocated to an intervention group (n = 21) and a control group (n = 25). The intervention group received aromatherapy massage three times per week for a period of 4 weeks...
July 2017: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/28585634/dual-external-field-responsive-polyaniline-coated-magnetite-silica-nanoparticles-for-smart-fluid-applications
#8
Jungchul Noh, Seunghee Hong, Chang-Min Yoon, Seungae Lee, Jyongsik Jang
In this communication, an electromagnetorheological fluid containing Fe3O4/SiO2/PANI nanoparticles is reported to demonstrate its controllable rheological properties under electric and magnetic fields. The EMR performance was significantly enhanced under the dual fields in the parallel direction.
June 16, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28565774/effects-of-ankaferd-bloodstopper-on-bone-healing-in-an-ovariectomized-osteoporotic-rat-model
#9
Şeref Ezirganli, Hakki Oğuz Kazancioğlu, Ahmet Hüseyin Acar, Hakan Özdemir, Emre Kuzu, Deniz Şahin İnan
Bone defects resulting from oncological surgical resections, congenital facial anomalies, trauma or infection represent a significant and common clinical problem. The present study aimed to evaluate the effects of a commercially-available medicinal plant extract product, Ankaferd BloodStopper (ABS), on bone healing. The present study was performed on 24 female ovariectomized (OVX) rats. A defect on each rat calvarium was created using a trephine burr prior to the rats being divided into two groups. Defects were grafted with a gelatin sponge soaked with normal saline (control group) or plant extract (experimental group)...
May 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28514139/bioorthogonal-protein-conjugation-application-to-the-development-of-a-highly-sensitive-bioluminescent-immunoassay-for-the-detection-of-interferon-%C3%AE
#10
Angeliki Moutsiopoulou, Eric Hunt, David Broyles, Christie Ataides Pereira, Kristen Woodward, Emre Dikici, Angel Kaifer, Sylvia Daunert, Sapna K Deo
Bioorthogonal conjugation eliminates the shortcomings of classical conjugation methods. The conjugation of antibodies to reporter proteins, such as bioluminescent protein, can be controlled with orthogonal conjugation methods. Here we report a bioluminescent immunoassay for the sensitive detection of interferon-γ (IFN-γ) that utilizes orthogonal conjugation of bioluminescent protein, Gaussia luciferase to anti-IFN-γ antibody. The IFN-γ is produced by the immune system and the detection of the IFN-γ is pivotal for the detection of persistent viral and bacterial infections...
June 21, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/28474945/environmentally-mediated-coherent-control-of-a-spin-qubit-in-diamond
#11
Scott E Lillie, David A Broadway, James D A Wood, David A Simpson, Alastair Stacey, Jean-Philippe Tetienne, Lloyd C L Hollenberg
The coherent control of spin qubits forms the basis of many applications in quantum information processing and nanoscale sensing, imaging, and spectroscopy. Such control is conventionally achieved by direct driving of the qubit transition with a resonant global field, typically at microwave frequencies. Here we introduce an approach that relies on the resonant driving of nearby environment spins, whose localized magnetic field in turn drives the qubit when the environmental spin Rabi frequency matches the qubit resonance...
April 21, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28473988/in-vitro-evaluation-of-manual-torque-values-applied-to-implant-abutment-complex-by-different-clinicians-and-abutment-screw-loosening
#12
Onur Dincer Kose, Burcin Karataslı, Sabit Demircan, Taha Emre Kose, Erhan Cene, Serhan Aydın Aya, Mehmet Ali Erdem, Abdulkadir Burak Cankaya
Preload is applied to screws manually or using a torque wrench in dental implant systems, and the preload applied must be appropriate for the purpose. The aim of this study was to assess screw loosening and bending/torsional moments applied by clinicians of various specialties following application of manual tightening torque to combinations of implants and abutments. Ten-millimeter implants of 3.7 and 4.1 mm diameters and standard or solid abutments were used. Each group contained five implant-abutment combinations...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28469833/use-of-electronic-medical-records-and-biomarkers-to-manage-risk-and-resource-efficiencies
#13
Dermot Ryan, John Blakey, Alison Chisholm, David Price, Mike Thomas, Björn Ställberg, Karin Lisspers, Janwillem W H Kocks
The migration from paper to electronic medical records (EMRs) was motivated by the administrative need to record, retrieve and process increasing amounts of clinical data in the 1980s. In the intervening period, there has been growing recognition of the potential of such records for achieving care efficiencies, informing clinical decision making and real-life research. EMRs can be used to characterise patient groups, management approaches and differential outcomes. Characterisation can also help with identification of potential biomarkers for future risk determination and likely treatment response...
2017: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28432015/blatm-2-0-a-genetic-tool-revealing-preferred-antiparallel-interaction-of-transmembrane-helix-4-of-the-dual-topology-protein-emre
#14
Ayse Julius, Lisa Laur, Christoph Schanzenbach, Dieter Langosch
Parallel and antiparallel transmembrane helix-helix interactions support the folding and non-covalent assembly of many integral membrane proteins. While several genetic tools are currently in use to study parallel transmembrane helix-helix interactions, antiparallel associations have been difficult to determine. Here, we present a novel genetic approach, termed BLaTM 2.0, which can be used in combination with the recently presented BLaTM 1.2 to compare the efficiency of antiparallel and parallel transmembrane domain (TMD) interactions in a natural membrane...
June 2, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28423123/n-acetylcysteine-versus-dopamine-to-prevent-acute-kidney-injury-after-cardiac-surgery-in-patients-with-preexisting-moderate-renal-insufficiency
#15
Omer Faruk Savluk, Fusun Guzelmeric, Yasemin Yavuz, Deniz Cevirme, Emre Gurcu, Halide Ogus, Tulay Orki, Tuncer Kocak
Objective: Acute kidney injury after cardiac surgery is associated with mortality and morbidity. Therefore, strategies to prevent acute kidney injury are very important. The aim of this placebo-controlled randomized double-blind study was to compare the prophylactic efficacy of N-Acetylcysteine and dopamine administration in patients with pre-existing moderate renal insufficiency who were undergoing cardiopulmonary bypass. Methods: This study included 135 patients with pre-existing moderate renal insufficiency who were scheduled for coronary artery bypass grafting surgery...
January 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28412052/-the-relationship-between-preoperative-anxiety-levels-and-vasovagal-incidents-during-the-administration-of-spinal-anesthesia
#16
Mürsel Ekinci, Birzat Emre Gölboyu, Onur Dülgeroğlu, Murat Aksun, Pınar Karaca Baysal, Erkan Cem Çelik, Ayşe Nur Yeksan
BACKGROUND: It was aimed to investigate the relationship between preoperative anxiety and vasovagal symptoms observed during the administration of spinal anesthesia in patients undergoing surgery in the perianal and inguinal regions. METHODS: The study included patients with planned surgery for inguinal hernia repair, anal fissure, hemorrhoid and pilonidal sinus excision. The study included a total of 210 patients of ASA I-II, aged 18-65 years. Patients were evaluated in respect of demographic characteristics, smoking and alcohol consumption, ASA grade and educational level...
April 12, 2017: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28410555/microwave-properties-of-one-dimensional-photonic-structures-based-on-composite-layers-filled-with-nanocarbon
#17
Ludmila Vovchenko, Oleg Lozitsky, Igor Sagalianov, Ludmila Matzui, Vilen Launets
This work presents the results of computer modeling and experimental measurements of microwave transmission properties for one-dimensional periodic multi-layered photonic structures (PCs), composed of epoxy layers and composite layers filled with nanocarbon particles-multi-walled carbon nanotubes and graphite nanoplatelets. The results show that the characteristics of observed photonic band gaps in transmission spectra of PC can be controlled by varying the parameters of layers, namely, the complex permittivity and the layer thickness...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28395258/a-pollution-fate-and-transport-model-application-in-a-semi-arid-region-is-some-number-better-than-no-number
#18
Zeynep Özcan, Oğuz Başkan, H Şebnem Düzgün, Elçin Kentel, Emre Alp
Fate and transport models are powerful tools that aid authorities in making unbiased decisions for developing sustainable management strategies. Application of pollution fate and transport models in semi-arid regions has been challenging because of unique hydrological characteristics and limited data availability. Significant temporal and spatial variability in rainfall events, complex interactions between soil, vegetation and topography, and limited water quality and hydrological data due to insufficient monitoring network make it a difficult task to develop reliable models in semi-arid regions...
October 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28391811/a-study-of-emr-based-medical-knowledge-network-and-its-applications
#19
Chao Zhao, Jingchi Jiang, Zhiming Xu, Yi Guan
BACKGROUND AND OBJECTIVE: Electronic medical records (EMRs) contain an amount of medical knowledge which can be used for clinical decision support. We attempt to integrate this medical knowledge into a complex network, and then implement a diagnosis model based on this network. METHODS: The dataset of our study contains 992 records which are uniformly sampled from different departments of the hospital. In order to integrate the knowledge of these records, an EMR-based medical knowledge network (EMKN) is constructed...
May 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28386594/nanotechnology-driven-therapeutic-interventions-in-wound-healing-potential-uses-and-applications
#20
REVIEW
Suzana Hamdan, Irena Pastar, Stefan Drakulich, Emre Dikici, Marjana Tomic-Canic, Sapna Deo, Sylvia Daunert
The chronic nature and associated complications of nonhealing wounds have led to the emergence of nanotechnology-based therapies that aim at facilitating the healing process and ultimately repairing the injured tissue. A number of engineered nanotechnologies have been proposed demonstrating unique properties and multiple functions that address specific problems associated with wound repair mechanisms. In this outlook, we highlight the most recently developed nanotechnology-based therapeutic agents and assess the viability and efficacy of each treatment, with emphasis on chronic cutaneous wounds...
March 22, 2017: ACS Central Science
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