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https://www.readbyqxmd.com/read/28526451/inter-delivery-weight-gain-and-risk-of-cesarean-delivery-following-a-prior-vaginal-delivery
#1
Annie M Dude, Abbi D Lane-Cordova, William A Grobman
BACKGROUND: Approximately 1/3 of all deliveries in the United States are via cesarean. Previous research indicates weight gain during pregnancy is associated with an increased risk of cesarean delivery. It remains unclear, however, whether and to what degree weight gain between deliveries (i.e., inter-delivery weight gain) is associated with cesarean delivery in a subsequent pregnancy following a vaginal delivery. OBJECTIVES: To determine whether inter-delivery weight gain is associated with an increased risk of intrapartum cesarean delivery following a vaginal delivery...
May 16, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28502760/patterns-of-gestational-weight-gain-and-birthweight-outcomes-in-the-eunice-kennedy-shriver-national-institute-of-child-health-and-human-development-fetal-growth-studies-singletons-a-prospective-study
#2
Sarah J Pugh, Paul S Albert, Sungduk Kim, William Grobman, Stefanie N Hinkle, Roger B Newman, Deborah A Wing, Katherine L Grantz
BACKGROUND: Inadequate or excessive total gestational weight gain is associated with increased risks of small- and large-for-gestational-age births, respectively, but evidence is sparse regarding overall and trimester-specific patterns of gestational weight gain in relation to these risks. Characterizing the interrelationship between patterns of gestational weight gain across trimesters can reveal whether the trajectory of gestational weight gain in the first trimester sets the path for gestational weight gain in subsequent trimesters, thereby serving as an early marker for at-risk pregnancies...
May 11, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28474356/patients-preferences-for-labor-analgesic-counseling-a-qualitative-analysis
#3
Paloma Toledo, Javiera Pumarino, William A Grobman, Cynthia A Wong, Jane L Holl, Romana Hasnain-Wynia
BACKGROUND: The decision to use, or not use, neuraxial labor analgesia is complex, with both maternal and fetal considerations. Fears and concerns about neuraxial analgesia may influence analgesic decision-making. Little is known about patients' preferences for analgesic counseling. Therefore, the objectives of this qualitative study were to evaluate the sources of information used by patients, the timing and content of antepartum counseling about labor analgesia, and patients' preferences for such counseling...
May 5, 2017: Birth
https://www.readbyqxmd.com/read/28450221/mothers-childhood-hardship-forecasts-adverse-pregnancy-outcomes-role-of-inflammatory-lifestyle-and-psychosocial-pathways
#4
Gregory E Miller, Jennifer Culhane, William Grobman, Hyagriv Simhan, Douglas E Williamson, Emma K Adam, Claudia Buss, Sonja Entringer, Kwang-Youn Kim, J Felipe Garcia-Espana, Lauren Keenan-Devlin, Thomas W McDade, Pathik D Wadhwa, Ann Borders
Research suggests the health consequences of economic hardship can be transmitted across generations. Some of these disparities are thought to be passed to offspring during gestation. But this hypothesis has not been tested in contemporary American samples, and the mechanisms of transmission have not been characterized. Accordingly, this study had two goals: first, to determine if women exposed to economic hardship during childhood showed higher rates of adverse birth outcomes; and second, to evaluate the contribution of inflammation, psychosocial, lifestyle, and obstetric characteristics to this phenomenon...
April 25, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28393386/maternal-depressive-symptoms-perceived-stress-and-fetal-growth
#5
William A Grobman, Deborah A Wing, Paul Albert, Sungduk Kim, Jagteshwar Grewal, Constance Guille, Roger Newman, Edward K Chien, John Owen, Mary E D'Alton, Ronald Wapner, Anthony Sciscione, Katherine L Grantz
OBJECTIVES: To determine whether longitudinal fetal growth is altered among pregnant women reporting greater perceived stress or more symptoms of depression. METHODS: This analysis was based on a multicenter longitudinal study of fetal growth. Women were screened at gestational ages of 8 weeks to 13 weeks 6 days for low-risk status and underwent serial sonographic examinations. At each study visit during pregnancy, women were asked to complete the Cohen Perceived Stress Scale (PSS) and Edinburgh Postpartum Depression Survey (EPDS)...
April 10, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28384838/maternal-income-during-pregnancy-is-associated-with-chronic-placental-inflammation-at-birth
#6
Lauren S Keenan-Devlin, Linda M Ernst, Kharah M Ross, Sameen Qadir, William A Grobman, Jane L Holl, Amy Crockett, Gregory E Miller, Ann E B Borders
Objective This study aims to examine whether maternal household income is associated with histological evidence of chronic placental inflammation. Study Design A total of 152 participants completed surveys of household income and consented to placenta collection at delivery and postpartum chart review for birth outcomes. Placental inflammatory lesions were evaluated via histological examination of the membranes, basal plate, and villous parenchyma by a single, experienced pathologist. Associations between household income and the presence of inflammatory lesions were adjusted for known perinatal risk factors...
April 6, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28383377/evaluation-of-introduction-of-a-delayed-cord-clamping-protocol-for-premature-neonates-in-a-high-volume-maternity-center
#7
Lilly Y Liu, Joe M Feinglass, Janine Y Khan, Susan E Gerber, William A Grobman, Lynn M Yee
OBJECTIVE: To evaluate adherence to a delayed cord clamping protocol for preterm births in the first 2 years after its introduction, perform a quality improvement assessment, and determine neonatal outcomes associated with protocol implementation and adherence. METHODS: This is a retrospective cohort study of women delivering singleton neonates at 23-32 weeks of gestation in the 2 years before (preprotocol) and 2 years after (postprotocol) introduction of a 30-second delayed cord clamping protocol at a large-volume academic center...
May 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28369543/sleep-during-pregnancy-the-numom2b-pregnancy-and-sleep-duration-and-continuity-study
#8
Kathryn J Reid, Francesca L Facco, William A Grobman, Corette B Parker, Marcos Herbas, Shannon Hunter, Robert M Silver, Robert C Basner, George R Saade, Grace W Pien, Shalini Manchanda, Judette M Louis, Chia-Lang Nhan-Chang, Judith H Chung, Deborah A Wing, Hyagriv N Simhan, David M Haas, Jay Iams, Samuel Parry, Phyllis C Zee
Study Objectives: To characterize sleep duration, timing and continuity measures in pregnancy and their association with key demographic variables. Methods: Multisite prospective cohort study. Women enrolled in the nuMoM2b study (nulliparous women with a singleton gestation) were recruited at the second study visit (16-21 weeks of gestation) to participate in the Sleep Duration and Continuity substudy. Women <18 years of age or with pregestational diabetes or chronic hypertension were excluded from participation...
May 1, 2017: Sleep
https://www.readbyqxmd.com/read/28364845/using-item-response-theory-to-optimize-measurement-of-chronic-stress-in-pregnancy
#9
Ann E B Borders, Jin-Shei Lai, Kaitlin Wolfe, Sameen Qadir, Jie Peng, Kwang-Youn Kim, Lauren Keenan-Devlin, Jane Holl, William Grobman
OBJECTIVE: Utilize Rasch analysis to develop an optimized self-reported measure of stress in pregnancy and examine the association with patient demographics and biologic measures of stress. STUDY DESIGN: Measured self-reported stress in pregnant women using 12 existing scales. Collected blood for biologic measures of stress (Epstein Barr Virus [EBV], C-Reactive Protein [CRP], Corticotropin Reactive Hormone [pCRH], and Adenocorticotropin Hormone [ACTH]). Used multidimensional scaling and Rasch analysis to produce an item reduced self-report measure...
May 2017: Social Science Research
https://www.readbyqxmd.com/read/28320597/racial-or-ethnic-and-socioeconomic-inequalities-in-adherence-to-national-dietary-guidance-in-a-large-cohort-of-us-pregnant-women
#10
Lisa M Bodnar, Hyagriv N Simhan, Corette B Parker, Heather Meier, Brian M Mercer, William A Grobman, David M Haas, Deborah A Wing, Matthew K Hoffman, Samuel Parry, Robert M Silver, George R Saade, Ronald Wapner, Jay D Iams, Pathik D Wadhwa, Michal Elovitz, Alan M Peaceman, Sean Esplin, Shannon Barnes, Uma M Reddy
BACKGROUND: The significance of periconceptional nutrition for optimizing offspring and maternal health and reducing social inequalities warrants greater understanding of diet quality among US women. OBJECTIVE: Our objective was to evaluate racial or ethnic and education inequalities in periconceptional diet quality and sources of energy and micronutrients. DESIGN: Cross-sectional analysis of data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be cohort...
March 14, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28291893/predictive-accuracy-of-serial-transvaginal-cervical-lengths-and-quantitative-vaginal-fetal-fibronectin-levels-for-spontaneous-preterm-birth-among-nulliparous-women
#11
M Sean Esplin, Michal A Elovitz, Jay D Iams, Corette B Parker, Ronald J Wapner, William A Grobman, Hyagriv N Simhan, Deborah A Wing, David M Haas, Robert M Silver, Matthew K Hoffman, Alan M Peaceman, Steve N Caritis, Samuel Parry, Pathik Wadhwa, Tatiana Foroud, Brian M Mercer, Shannon M Hunter, George R Saade, Uma M Reddy
Importance: Spontaneous preterm birth is a leading cause of infant mortality. Prediction, largely based on prior pregnancy outcomes, is not possible in women pregnant for the first time. Objective: To assess the accuracy of universal screening to predict spontaneous preterm birth in nulliparous women using serial measurements of vaginal fetal fibronectin levels and cervical length. Design, Settings, and Participants: A prospective observational cohort study of nulliparous women with singleton pregnancies, from 8 clinical sites across the United States between October 2010 and May 2014...
March 14, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28278278/dynamic-changes-of-the-respiratory-microbiota-and-its-relationship-to-fecal-and-blood-microbiota-in-healthy-young-cats
#12
Aida I Vientós-Plotts, Aaron C Ericsson, Hansjorg Rindt, Megan E Grobman, Amber Graham, Kaitlin Bishop, Leah A Cohn, Carol R Reinero
Advances in the field of metagenomics using culture-independent methods of microbial identification have allowed characterization of rich and diverse communities of bacteria in the lungs of healthy humans, mice, dogs, sheep and pigs. These data challenge the long held belief that the lungs are sterile and microbial colonization is synonymous with pathology. Studies in humans and animals demonstrate differences in the composition of airway microbiota in health versus disease suggesting respiratory dysbiosis occurs...
2017: PloS One
https://www.readbyqxmd.com/read/28277365/association-of-group-prenatal-care-with-gestational-weight-gain
#13
Michelle A Kominiarek, Amy Crockett, Sarah Covington-Kolb, Melissa Simon, William A Grobman
OBJECTIVE: To compare gestational weight gain among women in group prenatal care with that of women in individual prenatal care. METHODS: In this retrospective cohort study, women who participated in group prenatal care from 2009 to 2015 and whose body mass indexes (BMIs) and gestational weight gain were recorded were matched with the next two women who had the same payer type, were within 2-kg/m prepregnancy BMI and 2-week gestational age at delivery, and had received individual prenatal care...
April 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28263750/maternal-stress-and-neonatal-anthropometry-the-nichd-fetal-growth-studies
#14
Deborah A Wing, Ana M Ortega-Villa, William A Grobman, Mary L Hediger, Jagteshwar Grewal, Sarah J Pugh, Sungduk Kim, Roger Newman, Ed Chien, John Owen, Mary E D'Alton, Ronald Wapner, Anthony Sciscione, Paul S Albert, Katherine L Grantz
BACKGROUND: The effect of maternal mood disorders on neonatal measurements is not well-defined. The Fetal Growth Studies-Singletons provide a unique opportunity to evaluate the relationship between perceived maternal stress and neonatal growth measurements. OBJECTIVE: The purpose of this study was to determine whether perceived maternal stress during pregnancy is associated with anthropometric measurements in the neonate. STUDY DESIGN: This analysis was based on a prospective, multicenter longitudinal study of fetal growth...
March 3, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28240398/standardization-of-a-videofluoroscopic-swallow-study-protocol-to-investigate-dysphagia-in-dogs
#15
R A Harris, M E Grobman, M J Allen, J Schachtel, N E Rawson, B Bennett, J Ledyayev, B Hopewell, J R Coates, C R Reinero, T E Lever
BACKGROUND: Videofluoroscopic swallow study (VFSS) is the gold standard for diagnosis of dysphagia in veterinary medicine but lacks standardized protocols that emulate physiologic feeding practices. Age impacts swallow function in humans but has not been evaluated by VFSS in dogs. HYPOTHESIS/OBJECTIVES: To develop a protocol with custom kennels designed to allow free-feeding of 3 optimized formulations of contrast media and diets that address limitations of current VFSS protocols...
March 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28162769/cord-blood-biomarkers-of-placental-maternal-vascular-underperfusion-predict-bronchopulmonary-dysplasia-associated-pulmonary-hypertension
#16
Karen K Mestan, Nina Gotteiner, Nicolas Porta, William Grobman, Emily J Su, Linda M Ernst
OBJECTIVE: To assess whether cord blood biomarkers associated with placental maternal vascular underperfusion (MVU) are predictive of bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH). STUDY DESIGN: Premature infants enrolled in a longitudinal cohort study were randomly sampled from 4 gestational age strata (n = 190, range 23-36 weeks). Fifteen factors from a human angiogenesis panel were measured in cord blood using multiplex immunoassay...
February 2, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28153660/attempted-operative-vaginal-delivery-vs-repeat-cesarean-in-the-second-stage-among-women-undergoing-a-trial-of-labor-after-cesarean-delivery
#17
Moeun Son, Archana Roy, William A Grobman
BACKGROUND: It is not well-characterized whether attempting operative vaginal delivery is a safe and effective alternative among women who undergo a trial of labor after cesarean delivery who are unable to complete second-stage labor with a spontaneous vaginal delivery. OBJECTIVE: The purpose of this study was to compare maternal and neonatal outcomes that are associated with attempted operative vaginal delivery with those that are associated with second-stage repeat cesarean delivery without an operative vaginal delivery attempt among women who undergo a trial of labor after cesarean delivery...
January 30, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28056690/2017-guidelines-of-the-american-thyroid-association-for-the-diagnosis-and-management-of-thyroid-disease-during-pregnancy-and-the-postpartum
#18
Erik K Alexander, Elizabeth N Pearce, Gregory A Brent, Rosalind S Brown, Herbert Chen, Chrysoula Dosiou, William A Grobman, Peter Laurberg, John H Lazarus, Susan J Mandel, Robin P Peeters, Scott Sullivan
BACKGROUND: Thyroid disease in pregnancy is a common clinical problem. Since the guidelines for the management of these disorders by the American Thyroid Association (ATA) were first published in 2011, significant clinical and scientific advances have occurred in the field. The aim of these guidelines is to inform clinicians, patients, researchers, and health policy makers on published evidence relating to the diagnosis and management of thyroid disease in women during pregnancy, preconception, and the postpartum period...
March 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27960618/histologic-changes-of-mesenchymal-stem-cell-repair-of-tympanic-membrane-perforation
#19
Stefania Goncalves, Esperanza Bas, Michael Langston, Ariel Grobman, Bradley J Goldstein, Simon Angeli
CONCLUSION: Mesenchymal stem-cells are good candidates for cell-therapy of chronic tympanic membranes perforations. OBJECTIVES: To determine the effects of cell-based therapy in tympanic membrane perforations. METHODS: Young C57BL/6 mice were anesthetized with intraperitoneal administration of ketamine and xylazine and randomly divided into three groups (n = 4 ears/group) that underwent bilateral sub-total pars tensa perforations of equal sizes using a sterile 27-gauge needle under a surgical microscope...
December 14, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27939467/a-protocol-for-developing-disseminating-and-implementing-a-core-outcome-set-for-pre-eclampsia
#20
James M N Duffy, Janneke van 't Hooft, Chris Gale, Mark Brown, William Grobman, Ray Fitzpatrick, S Ananth Karumanchi, Nuala Lucas, Laura Magee, Ben Mol, Michael Stark, Shakila Thangaratinam, Mathew Wilson, Peter von Dadelszen, Paula Williamson, Khalid S Khan, Sue Ziebland, Richard J McManus
BACKGROUND: Pre-eclampsia is a serious complication of pregnancy and contributes to maternal and offspring mortality and morbidity. Randomised controlled trials evaluating therapeutic interventions for pre-eclampsia have reported many different outcomes and outcome measures. Such variation contributes to an inability to compare, contrast, and combine individual studies, limiting the usefulness of research to inform clinical practice. The development and use of a core outcome set would help to address these issues ensuring outcomes important to all stakeholders, including patients, will be collected and reported in a standardised fashion...
October 2016: Pregnancy Hypertension
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