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choriocapillaris

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https://www.readbyqxmd.com/read/28107073/choroidal-vasculopathy-and-retinal-detachment-in-a-bald-eagle-haliaeetus-leucocephalus-with-lead-toxicosis
#1
Ramzi Eid, David Sanchez-Migallon Guzman, Krista A Keller, K Tomo Wiggans, Christopher J Murphy, Elise E B LaDouceur, M Kevin Keel, Christopher M Reilly
A subadult male bald eagle ( Haliaeetus leucocephalus ) was presented for severe depression and weakness. Physical examination findings included depressed mentation, dehydration, sternal recumbency, poor body condition, and bilateral, whole-head, horizontal nystagmus. A heavy-metal panel was performed, and blood lead levels were 6.1 ppm. Treatment for lead poisoning was initiated, including subcutaneous fluids and parenteral calcium-disodium ethylenediaminetetraacetic acid, ceftiofur, and meloxicam. Ophthalmic examination findings included absent menace response, absent dazzle reflex, slow and incomplete direct pupillary light reflex, mild anterior uveitis, incipient cataracts, multifocal retinal tears, and retinal separation in both eyes...
December 2016: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/28101400/choriocapillaris-evaluation-in-choroideremia-using-optical-coherence-tomography-angiography
#2
Simon S Gao, Rachel C Patel, Nieraj Jain, Miao Zhang, Richard G Weleber, David Huang, Mark E Pennesi, Yali Jia
The choriocapillaris plays an important role in supporting the metabolic demands of the retina. Studies of the choriocapillaris in disease states with optical coherence tomography angiography (OCTA) have proven insightful. However, image artifacts complicate the identification and quantification of the choriocapillaris in degenerative diseases such as choroideremia. Here, we demonstrate a supervised machine learning approach to detect intact choriocapillaris based on training with results from an expert grader...
January 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28098203/optical-coherence-tomography-angiography-microvascular-findings-in-macular-edema-due-to-central-and-branch-retinal-vein-occlusions
#3
Mastropasqua Rodolfo, Toto Lisa, Di Antonio Luca, Borrelli Enrico, Senatore Alfonso, Di Nicola Marta, Di Martino Giuseppe, Ciancaglini Marco, Paolo Carpineto
The aim of this study was to evaluate retinal and choriocapillaris vessel density using optical coherence tomography angiography (OCTA) in eyes with central retinal vein occlusion (CRVO) and branch retinal vein occlusion (BRVO) complicated by macular edema (ME). Sixty eyes of 60 patients with CRVO or BRVO and ME and 40 healthy subjects underwent measurements of superficial and deep foveal and parafoveal vessel density (FVD, PFVD) and choricapillary density using OCTA at baseline and 60 days after intravitreal dexamethasone implant (IVDEX)...
January 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28092344/choriocapillaris-signal-voids-in-maternally-inherited-diabetes-and-deafness-and-in-pseudoxanthoma-elasticum
#4
Richard F Spaide
PURPOSE: To evaluate the pattern of choriocapillaris signal voids in maternally inherited diabetes and deafness and in pseudoxanthoma elasticum in eyes before the development of any geographic atrophy. METHODS: The choriocapillaris under the central macula was imaged with the Optovue RTVue XR Avanti using a 10 μm slab thickness. Automatic local thresholding of the resultant raw data extracted areas of absent flow signal, called signal voids, and these were counted and logarithmically binned...
January 13, 2017: Retina
https://www.readbyqxmd.com/read/28091938/distinguishing-features-of-acute-vogt-koyanagi-harada-disease-and-acute-central-serous-chorioretinopathy-on-optical-coherence-tomography-angiography-and-en-face-optical-coherence-tomography-imaging
#5
Kanika Aggarwal, Aniruddha Agarwal, Ankit Deokar, Sarakshi Mahajan, Ramandeep Singh, Reema Bansal, Aman Sharma, Mangat R Dogra, Vishali Gupta
BACKGROUND: The aim of this study is to determine the differences in optical coherence tomography angiography (OCTA) features of acute Vogt-Koyanagi-Harada disease (VKH) and acute central serous chorioretinopathy (CSC). Clinical and imaging data of patients with acute CSC and VKH in a tertiary-care institute were analyzed. Multimodal imaging including fluorescein angiography, indocyanine green angiography (ICGA), and enhanced-depth imaging OCT were performed. OCTA images were analyzed for alterations in retinochoroidal microvasculature...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28088509/choroidal-neovascularization-in-malattia-leventinese-diagnosed-using-optical-coherence-tomography-angiography
#6
Rita Serra, Florence Coscas, Nabil Messaoudi, Mayer Srour, Eric Souied
PURPOSE: To compare Optical Coherence Tomography Angiography (OCT-A) with traditional multimodal imaging in patients with Malattia Leventinese DESIGN: Retrospective case series. METHODS: Eight eyes of four consecutive patients with Malattia Leventinese were retrospectively studied. All patients underwent a complete ophthalmological examination including color fundus photography, fluorescein and indocyanine green angiographies, Spectral Domain Optical Coherence Tomography and Optical Coherence Tomography Angiography...
January 11, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28079756/optical-coherence-tomography-angiography-changes-in-early-type-3-neovascularization-after-anti-vascular-endothelial-growth-factor-treatment
#7
Alexandra Miere, Giuseppe Querques, Oudy Semoun, Francesca Amoroso, Olivia Zambrowski, Thibaut Chapron, Vittorio Capuano, Eric H Souied
PURPOSE: To investigate the morphologic changes on optical coherence tomography angiography (OCTA) of treatment-naive Type 3 neovascularization secondary to exudative age-related macular degeneration after 1 year of anti-vascular endothelial growth factor therapy. METHODS: Consecutive patients diagnosed with treatment-naive early-stage Type 3 neovascularization were enrolled in this retrospective study. All patients underwent color fundus photographs/MultiColor (Heidelberg Engineering) imaging, fluorescein angiography, indocyanine green angiography, structural spectral domain OCT, and OCTA Optovue RTVue XR Avanti (Optovue) at baseline, and repeated OCTA and structural spectral domain OCT at Month 12...
January 10, 2017: Retina
https://www.readbyqxmd.com/read/28076569/optical-coherence-tomography-of-macular-atrophy-associated-with-microcephaly-and-presumed-intrauterine-zika-virus-infection
#8
Adriana Gondim de Moura Campos, Rodrigo Pessoa Cavalcanti Lira, Tiago Eugenio Faria E Arantes
This case report describes the retinal optical coherence tomography (OCT) findings in a microcephalic infant with macular atrophy presumably caused by intrauterine Zika virus infection. OCT demonstrated atrophy of the outer retinal layers and choriocapillaris, including the outer nuclear layer and ellipsoid zone, associated with retinal pigment epithelium hyper-reflectivity and increased OCT penetration into deeper layers of the choroid and sclera. A major concern associated with this infection is the apparent increased incidence of microcephaly in fetuses born to mothers infected with the Zika virus...
November 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28062428/optical-coherence-tomography-angiography-and-fundus-autofluorescence-in-the-eyes-with-choroideremia
#9
Maki Kato, Ichiro Maruko, Hideki Koizumi, Tomohiro Iida
A 65-year-old man with presumed choroideremia with preserved central vision was examined by fundus autofluorescence (FAF) and optical coherence tomography angiography (OCTA). FAF showed an isolated area of hyperautofluorescence that involved the fovea. Although the choroid capillary slab of the OCTA showed the medium and large choroidal vessels inferior to the area of retinal pigment epithelium (RPE) atrophy, the choriocapillaris was visible in a relatively wider area than the hyperautofluorescent area in the FAF images...
January 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28060397/swept-source-oct-angiography-shows-sparing-of-the-choriocapillaris-in-multiple-evanescent-white-dot-syndrome
#10
Nicolas A Yannuzzi, Swarup S Swaminathan, Fang Zheng, Andrew Miller, Giovanni Gregori, Janet L Davis, Philip J Rosenfeld
Two women with unilateral vision loss from multiple evanescent white dot syndrome were imaged serially with swept-source optical coherence tomography (SS-OCT). En face wide-field structural images revealed peripapillary outer photoreceptor disruption better than conventional fundus autofluorescence imaging. OCT angiography (OCTA) imaging showed preservation of flow within the retinal vasculature and choriocapillaris. As OCTA imaging of the choriocapillaris continues to evolve, these images may lay the groundwork for future investigation...
January 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28057649/choroid-morphometric-analysis-in-non-neovascular-age-related-macular-degeneration-by-means-of-optical-coherence-tomography-angiography
#11
Maria Vittoria Cicinelli, Alessandro Rabiolo, Alessandro Marchese, Luigi de Vitis, Adriano Carnevali, Lea Querques, Francesco Bandello, Giuseppe Querques
AIMS: To describe the vascular changes in patients affected by non-neovascular age-related macular degeneration (AMD), featuring reticular pseudodrusen (RPD), drusen, or both RPD and drusen by means of optical coherence tomography angiography (OCT-A). METHODS: Cross-sectional observational case series. Patients with non-neovascular AMD presenting at the Medical Retina Service of the Department of Ophthalmology, University Vita-Salute San Raffaele in Milan were recruited...
January 5, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28033230/serpiginous-choroiditis-imaged-by-optical-coherence-tomography-angiography
#12
Alaʼa El Ameen, Carl P Herbort
PURPOSE: To report a case of serpiginous choroiditis imaged with optical coherence tomography angiography (OCT-A). METHODS: Case report. RESULTS: Multimodal imaging and OCT-A were performed to investigate serpiginous choroiditis in a 65-year-old patient. Comparison between OCT-A images and intermediate and late phase indocyanine green angiography revealed that the hypofluorescent areas on indocyanine green angiography corresponded topographically to the dark areas seen in the choriocapillaris layer of OCT-A...
December 28, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28009412/optical-coherence-tomography-angiography-of-polypoidal-neovascularization-associated-with-choroidal-nevus
#13
Maria Vittoria Cicinelli, Lorenzo Iuliano, Alessandro Rabiolo, Alessandro Marchese, Giuseppe Querques, Francesco Bandello
PURPOSE: To report a case of juxtapapillary polypoidal choroidal neovascularization (PCNV) associated with choroidal nevus investigated by means of optical coherence tomography angiography (OCT-A). METHODS: Case report. RESULTS: A 72-year-old woman presented with visual loss and metamorphopsia in her left eye for 5 days secondary to PCNV that developed on the border of a juxtapapillary choroidal nevus. Fluorescein angiography, indocyanine green angiography, and spectral-domain OCT confirmed the diagnosis...
November 28, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28009410/optical-coherence-tomography-angiography-findings-in-laser-maculopathy
#14
Livia Tomasso, Lucia Benatti, Carlo La Spina, Rosangela Lattanzio, Giovanni Baldin, Adriano Carnevali, Luigi A De Vitis, Lea Querques, Francesco Bandello, Giuseppe Querques
PURPOSE: Handheld laser pointer thermal injury affects primarily the retinal pigment epithelium (RPE). However, so far no study has reported on the possible effects of laser pointers in the deeper layers, beneath the RPE. Here, we describe the spectral-domain optical coherence tomography angiography findings in the choriocapillaris of a patient with laser maculopathy. METHODS: A 13-year-old boy presented to our department with decreased vision in the left eye 12 hours after having stared at the beam of a laser pointer...
November 28, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28009403/ocular-pulse-amplitude-after-panretinal-photocoagulation-in-normotensive-eyes-with-proliferative-diabetic-retinopathy
#15
Marija M Bozic, Jelena B Karadzic, Igor M Kovacevic, Ivan S Marjanovic
PURPOSE: To assess the effect of panretinal laser photocoagulation on ocular pulse amplitude (OPA) in normotensive eyes with proliferative diabetic retinopathy. METHODS: Prospectively, we performed unilateral argon laser panretinal photocoagulation (PRP) in 30 patients with diabetes mellitus type II and previously untreated bilateral proliferative diabetic retinopathy. Before and 7 and 30 days after the treatment, OPA was measured using dynamic contour tonometer...
November 28, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28005676/en-face-optical-coherence-tomography-and-optical-coherence-tomography-angiography-of-multiple-evanescent-white-dot-syndrome-new-insights-into-pathogenesis
#16
Francesco Pichi, Sunil K Srvivastava, Saradha Chexal, Andrea Lembo, Luiz H Lima, Piergiorgio Neri, Andrea Saitta, Jay Chhablani, Thomas A Albini, Paolo Nucci, K Bailey Freund, Hyewon Chung, Careen Y Lowder, David Sarraf
PURPOSE: To localize the various levels of abnormalities in multiple evanescent white dot syndrome by comparing "en face" optical coherence tomography (OCT) and OCT angiography with various conventional imaging modalities. METHODS: In this retrospective case series, multimodal imaging was performed in 9 retinal centers on 36 patients with multiple evanescent white dot syndrome and included widefield fundus autofluorescence (FAF), fluorescein angiography (FA), and indocyanine green angiography, and B-scan and "en face" C-scan enhanced depth imaging and spectral domain OCT...
December 2016: Retina
https://www.readbyqxmd.com/read/28005665/choroidal-morphology-in-eyes-with-polypoidal-choroidal-vasculopathy-and-normal-or-subnormal-subfoveal-choroidal-thickness
#17
Won Ki Lee, Jiwon Baek, Kunal K Dansingani, Jae Hyung Lee, K Bailey Freund
PURPOSE: To subsegment the choroid in patients with polypoidal choroidal vasculopathy and to determine whether the ratio of choriocapillaris/Sattler layer thickness to total choroidal thickness is decreased at sites of polypoidal pathology. METHODS: Retrospective, observational, cross-sectional study. A total of 320 eyes of 305 patients with polypoidal choroidal vasculopathy were studied with optical coherence tomography and dye angiography. The ratio of choriocapillaris/Sattler layer thickness to total choroidal thickness was calculated at polypoidal lesion sites in eyes with subfoveal choroidal thickness (SFCT) ≤200 μm...
December 2016: Retina
https://www.readbyqxmd.com/read/28005659/swept-source-optical-coherence-tomography-angiography-reveals-choriocapillaris-alterations-in-eyes-with-nascent-geographic-atrophy-and-drusen-associated-geographic-atrophy
#18
Eric M Moult, Nadia K Waheed, Eduardo A Novais, WooJhon Choi, ByungKun Lee, Stefan B Ploner, Emily D Cole, Ricardo N Louzada, Chen D Lu, Philip J Rosenfeld, Jay S Duker, James G Fujimoto
PURPOSE: To investigate choriocapillaris (CC) alteration in patients with nascent geographic atrophy (nGA) and/or drusen-associated geographic atrophy (DAGA) using swept-source optical coherence tomography angiography (OCTA). METHODS: A 1,050-nm wavelength, 400 kHz A-scan rate swept-source optical coherence tomography prototype was used to perform volumetric swept-source optical coherence tomography angiography over 6 mm × 6 mm fields of view in patients with nGA and/or DAGA...
December 2016: Retina
https://www.readbyqxmd.com/read/28003976/application-of-optical-coherence-tomography-angiography-in-assessment-of-posterior-scleral-reinforcement-for-pathologic-myopia
#19
Jing Mo, An-Li Duan, Szy-Yann Chan, Xue-Fei Wang, Wen-Bin Wei
AIM: To investigate the effect of posterior scleral reinforcement (PSR) on circulation of pathologic myopia eyes with posterior staphyloma by optical coherence tomography angiography (OCTA). METHODS: The study included 30 pathologic myopia eyes with posterior staphyloma which underwent PSR (PSR group) for 6 to 18mo ago, and 30 age and myopia matched eyes without PSR surgery as control group. Macular, choriocapillaris and radial peripapillary capillary (RPC) flow density were measured by OCTA, and the measurements were compared between groups...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28003730/accumulation-of-cholesterol-and-increased-demand-for-zinc-in-serum-deprived-rpe-cells
#20
Sanghamitra Mishra, Katherine Peterson, Lili Yin, Alan Berger, Jianguo Fan, Graeme Wistow
PURPOSE: Having observed that confluent ARPE-19 cells (derived from human RPE) survive well in high-glucose serum-free medium (SFM) without further feeding for several days, we investigated the expression profile of RPE cells under the same conditions. METHODS: Expression profiles were examined with microarray and quantitative PCR (qPCR) analyses, followed by western blot analysis of key regulated proteins. The effects of low-density lipoprotein (LDL) and zinc supplementation were examined with qPCR...
2016: Molecular Vision
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