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https://www.readbyqxmd.com/read/28902333/multi-modal-imaging-including-optical-coherence-tomography-angiography-in-patients-with-posterior-multifocal-placoid-pigment-epitheliopathy
#1
Jens Ulrich Werner, Christian Enders, Gerhard Klaus Lang, Gabriele Elisabeth Lang
BACKGROUND AND OBJECTIVE: New imaging methods provide novel insights into the pathogenesis of acute posterior multifocal placoid pigment epitheliopathy (APMPPE). PATIENTS AND METHODS: Four patients (eight eyes) in acute, subacute, and late phases of the disease were analyzed with multi-modal imaging methods including optical coherence tomography angiography (OCTA), structural OCT, fundus photography, and fundus autofluorescence. One patient was observed during the entire disease course...
September 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28895631/-oct-angiography-of-rpe-tears-in-exudative-amd-morpohological-analysis-of-the-choriocapillaris-and-the-rpe
#2
Matthias Gutfleisch, Kai Rothaus, Marie-Louise Farecki, Henrik Faatz, Britta Heimes-Bussmann, Frederic Gunnemann, Martin Ziegler, Ioannis Papapostolou, Albrecht Lommatzsch, Daniel Pauleikoff
Background Retinal pigment epithelium (RPE) tears are a typical complication of vascular pigment epithelium detachment in age-related macular degeneration (AMD). During proactive intense anti-VEGF therapy, stabilisation or improvement of function may occur. With the new method of OCT angiography (OCT-A), retinal vessels and flow density can be quantified. This pilot study investigates changes in the choriocapillars (CC) in areas with increasing FAF in OCT following an RPE-tear. Methods In six eyes with an RPE-tear, prospectively initially and every three months thereafter, multimodal imaging was performed, including fundus autofluorescence (FAF) (HRA2, Heidelberg Engineering, Heidelberg, Deutschland) and OCT-A (RTVue XR Avanti, SSDA-Modus, Angiovue, Optovue, Freemont, CA, USA)...
September 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28894975/reperfusion-of-the-choriocapillaris-observed-using-optical-coherence-tomography-angiography-in-hypertensive-choroidopathy
#3
Miwa Saito, Akihiro Ishibazawa, Reiko Kinouchi, Akitoshi Yoshida
PURPOSE: Optical coherence tomography angiography (OCTA) can visualize the vascular status of the choriocapillaris noninvasively and separately from the other vascular beds. We describe focal ischemia in the choriocapillaris and reperfusion of the area in hypertensive choroidopathy using en-face OCTA. CASE: A 32-year-old woman diagnosed with pregnancy-induced hypertension presented with acute anorthopia in the right eye after delivery via Caesarian section. Fundus examination showed an Elschnig's spot and serous retinal detachment (SRD) in the inferior perifoveal region...
September 11, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28890078/choroidal-thinning-associated-with-hydroxychloroquine-retinopathy
#4
Seong Joon Ahn, So Jung Ryu, Joo Young Joung, Byung Ro Lee
PURPOSE: To investigate choroidal thickness in patients using hydroxychloroquine (HCQ) and compare choroidal thickness between eyes with and without HCQ retinopathy. DESIGN: Retrospective case series METHODS: Setting: Institutional Patients: We included 124 patients with systemic lupus erythematosus or rheumatoid arthritis who were treated with HCQ. The patients were divided into an HCQ retinopathy group and a control group, according to the presence or absence of HCQ retinopathy...
September 7, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28886928/geographic-atrophy-etiopathogenesis-and-current-therapies
#5
M Sastre-Ibáñez, A Barreiro-González, R Gallego-Pinazo, R Dolz-Marco, B García-Armendariz
Geographic atrophy is characterized by severe visual deficit whose etiology and pathophysiology are yet to be elucidated. As a working hypothesis, oxidative damage could trigger a chronic inflammation in Bruch's membrane-RPE-choriocapillaris complex, mostly due to complement pathway overactivation. Some individuals with mutations in the complement system and other factors have diminished capacity in the modulation of the inflammatory response, which results in cell damage and waste accumulation. This accumulation of intracellular and extracellular waste products manifests as drusen and pigmentary changes that precede the atrophy of photoreceptors, RPE, choriocapillaris with an ischemic process with decreased choroid flow...
September 5, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28875282/refining-coats-disease-by-ultra-widefield-imaging-and-optical-coherence-tomography-angiography
#6
Alessandro Rabiolo, Alessandro Marchese, Riccardo Sacconi, Maria Vittoria Cicinelli, Andrea Grosso, Lea Querques, Giuseppe Querques, Francesco Bandello
PURPOSE: The purpose of our study was to describe ultra-widefield (UWF) imaging and optical coherence tomography angiography (OCT-A) findings in affected and fellow eyes of patients with Coats' disease. METHODS: Consecutive patients affected by Coats' disease were prospectively recruited at the Department of Ophthalmology, San Raffaele Hospital, Milan, Italy in this cross-sectional, observational study. Patients underwent UWF color fundus photographs, UWF green autofluorescence, UWF fluorescein angiography (FA), optical coherence tomography (OCT), with 3 × 3 mm and 6 × 6 mm OCT-A scans of the macula...
September 5, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28868031/optical-coherence-tomography-angiography-employing-a-novel-technique-for-investigation-in-vogt-koyanagi-harada-disease
#7
Panagiotis Giannakouras, Konstantinos Andreanos, Barbara Giavi, Andreas Diagourtas
PURPOSE: To report a case of Vogt-Koyanagi-Harada (VKH) disease and describe the imaging findings by means of optical coherence tomography angiography (OCTA). METHODS: Medical and ophthalmological history, ophthalmological examination, laboratory evaluation, B-scan ultrasonography, fluorescein and indocyanine angiography, and optical coherence tomography (OCT) were performed at baseline, as well as OCTA. RESULTS: A 50-year-old healthy female presented with decreased vision in both eyes...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28855197/optical-coherence-tomography-angiography-reproducibility-of-lesion-size-measurements-in-neovascular-age-related-macular-degeneration-amd
#8
Francesca Amoroso, Alexandra Miere, Oudy Semoun, Camille Jung, Vittorio Capuano, Eric H Souied
PURPOSE: To evaluate the reproducibility and interuser agreement of measurements of choroidal neovascularisation in optical coherence tomography angiography (OCTA). DESIGN: Prospective non-interventional study. METHODS: Consecutive patients, presenting with neovascular age-related macular degeneration (AMD), underwent two sequential OCTA examinations (AngioVue, Optovue, Fremont, California, USA), performed by the same trained examiner. Neovascular lesion area was then measured on both examinations in the choriocapillaris automatic segmentation by two masked readers, using the semiautomated measuring software embedded in the instrument...
August 30, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28832738/multimodal-assessment-of-patients-with-chronic-central-serous-chorioretinopathy
#9
Karlos Ítalo Souza Viana, Pedro M Souza Leão, Letícia Fernandes, Rubens Siqueira, Jefferson Ribeiro, Rodrigo Jorge
PURPOSE: To examine differences between fluorescein angiography (FA) and indocyanine green angiography (ICG) findings in patients with chronic central serous chorioretinopathy (CSC), comparing these with optical coherence tomography (OCT) findings. METHODS: Ten consecutive patients with chronic CSC (19 eyes; 7 men; mean age, 50.7 ± 8.4 years) underwent multimodal evaluation that included FA, ICG, and OCT (Spectralis HRA-OCT, Heidelberg Engineering, Heidelberg, Germany)...
June 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28827524/in-vivo-assessment-of-macula-in-eyes-of-healthy-children-8-to-16-years-old-using-optical-coherence-tomography-angiography
#10
Zhengwei Zhang, Xiaoli Huang, Xiaomei Meng, Tiantian Chen, Yan Gu, Yan Wu, Zhifeng Wu
The purpose of the present study was to investigate the vascular flow density (VD) of macular superficial (SCP), deep capillary plexus (DCP), and choriocapillaris and the size of the foveal avascular zone (FAZ) area in healthy children using optical coherence tomography angiography (OCTA). The potential associations of age, sex, intraocular pressure, body mass index, spherical equivalent, and axial length with OCTA parameters were also investigated. A total of 75 eyes from 75 healthy children were included for analysis, with the mean age 11...
August 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28820167/swept-source-optical-coherence-tomography-angiography-of-choroid-in-choroidal-hemangioma-before-and-after-laser-photocoagulation
#11
Rohan Chawla, Koushik Tripathy, Anu Sharma, Rajpal Vohra
Swept source optical coherence tomography-angiography (OCT-angiography) gives us a unique opportunity to study the vasculature of choroidal lesions in vivo. We describe the OCT angiographic characteristics of circumscribed choroidal hemangioma before and after laser photocoagulation. Medium-sized choroidal vessels/vessels on the tumor surface become predominantly visible after laser photocoagulation due to laser-induced damage to the overlying choriocapillaris. OCT-angiography adds a new dimension to in vivo analysis of vascular changes in choroid due to choroidal tumors and their response to therapy...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28817420/optical-coherence-tomography-angiography-for-the-detection-of-secondary-choroidal-neovascularization-in-vitelliform-macular-dystrophy
#12
Martin Stattin, Daniel Ahmed, Carl Glittenberg, Ilse Krebs, Siamak Ansari-Shahrezaei
PURPOSE: Optical coherence tomography angiography (OCTA) is used to assess vascular abnormality in advanced stage vitelliform macular dystrophy (VMD2). METHODS: Multimodal imaging including spectral domain (SD) OCT, autofluorescence (AF), fluorescein (FA) and indocyanine green angiography (ICGA) as well as optical coherence tomography angiography were performed. PATIENTS: Two eyes in one young patient with diagnosed vitelliform macular dystrophy were investigated for progressive visual dysfunction...
August 16, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28810037/quantitative-features-of-the-choriocapillaris-in-healthy-individuals-using-swept-source-optical-coherence-tomography-angiography
#13
Mayss Al-Sheikh, Khalil Ghasemi Falavarjani, Maximilian Pfau, Akihito Uji, Phillip P Le, SriniVas R Sadda
BACKGROUND AND OBJECTIVE: To quantify vessel density (VD) and grey value (GV) as a measure of flow in the choriocapillaris (CC) in healthy subjects with optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: In this prospective, noncomparative case series, 3 mm × 3 mm OCTA images of 36 eyes of 22 healthy individuals were obtained using a swept-source instrument. VD and GV levels were calculated on CC en face slabs in the central 1-mm (subfoveal field) and surrounding 2...
August 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28810036/evaluation-of-macular-perfusion-in-healthy-smokers-by-using-optical-coherence-tomography-angiography
#14
Ziya Ayhan, Mahmut Kaya, Taylan Ozturk, Omer Karti, F Hakan Oner
BACKGROUND AND OBJECTIVE: To investigate the macular perfusion changes in healthy smokers by using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: OCTA measurements were taken for the right eyes of 40 smokers (Group 1) and age- and sex-matched control cases (Group 2). Group 1 underwent OCTA scanning with the XR Avanti AngioVue OCTA (Optovue, Fremont, CA) at baseline and at 5 minutes, 30 minutes, and 60 minutes after one standard cigarette smoking...
August 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28796562/loss-of-endothelial-planar-cell-polarity-and-cellular-clearance-mechanisms-in-age-related-macular-degeneration
#15
Maria Mercedes Campos, Mones S Abu-Asab
Apoptosis, autophagosomes, and lysosomes are lacking in the retinal pigment epithelium (RPE) of age-related macular degeneration (AMD) eyes. Necrosis, not apoptosis, appeared to be the prominent type of cell death in RPE, which led to the accumulation of cell debris within and on both sides of Bruch's membrane. The endothelium of the choriocapillaris had an altered planar cell polarity which encompassed the disappearance of fenestrations, the thickening of cytoplasm, and anterior nuclear dislocation. There were no significant differences in RPE and choroidal aberrations between macular and temporal regions...
August 10, 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28795246/bilateral-multiple-evanescent-white-dot-syndrome
#16
Chiara Veronese, Chiara Maiolo, Mariachiara Morara, Grayson W Armstrong, Antonio P Ciardella
PURPOSE: To present a single case of bilateral multiple evanescent white dot syndrome (MEWDS). METHODS: A single case with three months of follow-up using imaging studies including fundus color photography (FP), fluorescein angiography (FA), indocyanine green angiography (ICGA), fundus autofluorescence (FAF), spectral-domain optical coherence tomography (SD-OCT), en face SD-OCT and optical coherence tomography angiography (OCTA) is presented. RESULTS: The patient presented with bilateral MEWDS, ultimately with complete resolution of symptoms...
August 9, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28767554/comparison-of-optical-coherence-tomography-angiographic-changes-after-anti-vascular-endothelial-growth-factor-therapy-alone-or-in-combination-with-photodynamic-therapy-in-polypoidal-choroidal-vasculopathy
#17
Kelvin Yi Chong Teo, Yasuo Yanagi, Shu Yen Lee, Ian Yew San Yeo, Gavin Siew Wei Tan, Ranjana Mathur, Choi Mun Chan, Tien Yin Wong, Chui Ming Gemmy Cheung
PURPOSE: To compare changes in optical coherence tomography angiography in eyes with polypoidal choroidal vasculopathy after treatment with anti-vascular endothelial growth factor monotherapy or combined with photodynamic therapy. METHODS: This is a longitudinal case-controlled study. The authors performed optical coherence tomography angiography at baseline and Month 3 in patients with treatment-naive polypoidal choroidal vasculopathy undergoing monotherapy (n = 10) or combination therapy (n = 13)...
August 1, 2017: Retina
https://www.readbyqxmd.com/read/28765145/optical-coherence-tomography-angiography-characterisation-of-best-disease-and-associated-choroidal-neovascularisation
#18
Abhilash Guduru, Arushi Gupta, Mudit Tyagi, Subhadra Jalali, Jay Chhablani
AIMS: To characterise the vasculature of the retina in patients with Best vitelliform dystrophy, including those with choroidal neovascularisation (CNV), using optical coherence tomography angiography (OCTA) and correlate with fluorescein angiography (FA). METHODS: This prospective observational study included 19 eyes of 10 patients with Best disease. Using OCTA, all layers of retina were qualitatively characterised for each eye. Patients with CNV also underwent FA, and areas of CNV were measured by OCTA and FA and correlated...
August 1, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28763560/choroidal-vasculature-in-bietti-crystalline-dystrophy-with-cyp4v2-mutations-and-in-retinitis-pigmentosa-with-eys-mutations
#19
Takako Hirashima, Manabu Miyata, Kenji Ishihara, Tomoko Hasegawa, Masako Sugahara, Ken Ogino, Munemitsu Yoshikawa, Masayuki Hata, Yoshimasa Kuroda, Yuki Muraoka, Sotaro Ooto, Nagahisa Yoshimura
Purpose: We compare the choroidal vascular area between Bietti crystalline dystrophy (BCD) patients with CYP4V2 mutations, retinitis pigmentosa (RP) patients with EYS mutations, and normal controls, and investigate the correlation between choroidal vascular area and associated parameters. Methods: This prospective case-series study included consecutive nine eyes of nine BCD patients with CYP4V2 mutations (BCD group), 16 eyes of 16 RP patients with EYS mutations (EYS-RP group), and 16 eyes of 16 normal volunteers matched for age and axial length (control group)...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28715591/choriocapillaris-flow-in-myopia
#20
Richard F Spaide
No abstract text is available yet for this article.
July 1, 2017: Investigative Ophthalmology & Visual Science
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