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https://www.readbyqxmd.com/read/29334345/arm-crank-ergometry-improves-cardiovascular-disease-risk-factors-and-community-mobility-independent-of-body-composition-in-high-motor-complete-spinal-cord-injury
#1
James J Bresnahan, Gary J Farkas, Jody L Clasey, James W Yates, David R Gater
OBJECTIVE: Evaluate the effect of aerobic exercise using arm crank ergometry (ACE) in high motor complete (ISNCSCI A/B) spinal cord injury (SCI) as primarily related to cardiovascular disease (CVD) risk factors and functional mobility and secondarily to body composition and metabolic profiles. DESIGN: Longitudinal interventional study at an academic medical center. METHODS: Ten previously untrained participants (M8/F2, Age 36.7 y ± 10.1, BMI 24...
January 15, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29330182/fluorescence-recovery-allows-the-implementation-of-a-fluorescence-reporter-gene-platform-applicable-for-the-detection-and-quantification-of-horizontal-gene-transfer-in-anoxic-environments
#2
Rafael Pinilla, Leise Riber, Søren J Sørensen
The study of horizontal gene transfer (HGT) in microbial communities has been revolutionized by significant advances in cultivation-independent methods based on fluorescence reporter gene technologies. Recently, the combination of these novel approaches with flow cytometry has presented itself as one of the most powerful tools to study the spread of mobile genetic elements (MGEs) in the environment. However, the use of fluorescent markers like green fluorescent protein (GFP) and mCherry is limited by environmental constraints that affect the correct maturation of their fluorophores, such as oxygen availability and pH levels...
January 12, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29330132/an-overview-of-the-safety-pharmacology-society-strategic-plan
#3
M K Pugsley, S Authier, J E Koerner, W S Redfern, C G Markgraf, T Brabham, K Correll, M V Soloviev, A Botchway, M Engwall, M Traebert, J-P Valentin, T J Mow, A Greiter-Wilke, D J Leishman, H M Vargas
Safety Pharmacology studies are conducted to characterize the confidence by which biologically active new chemical entities (NCE) may be anticipated as safe. Non-clinical safety pharmacology studies aim to detect and characterize potentially undesirable pharmacodynamic activities using an array of in silico, in vitro and in vivo animal models. While a broad spectrum of methodological innovation and advancement of the science occurs within the Safety Pharmacology Society, the society also focuses on partnerships with health authorities and technology providers and facilitates interaction with organizations of common interest such as pharmacology, physiology, neuroscience, cardiology and toxicology...
January 9, 2018: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/29330073/the-association-of-clinic-based-mobility-tasks-and-measures-of-community-performance-and-risk
#4
M L Callisaya, J Verghese
INTRODUCTION: Gait speed is recognized as an important predictor of adverse outcomes in older people. However, it is unknown if other more complex mobility tasks are better predictors of such outcomes. OBJECTIVE: To examine a range of clinic-based mobility tests and determine which were most strongly associated with measures of community performance and risk (CP&R). DESIGN: Cross-sectional study SETTING: Central Control Mobility and Aging Study, Westchester County, New York PARTICIPANTS: Aged ≥ 65 years (n=424) METHODS: Clinic-based mobility measures included gait speed measured during normal and dual-task conditions, the Floor Maze Immediate and Delay tasks, and stair ascending and descending...
January 9, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29329087/occurrence-of-perfluoroalkyl-substances-pfas-in-garden-produce-at-homes-with-a-history-of-pfas-contaminated-drinking-water
#5
Deanna P Scher, James E Kelly, Carin A Huset, Kitrina M Barry, Richard W Hoffbeck, Virginia L Yingling, Rita B Messing
The decades-long disposal of manufacturing waste containing perfluoroalkyl substances (PFAS) in landfills resulted in contamination of groundwater serving as the drinking water supply for the eastern Twin Cities metropolitan region. While measures were taken to reduce the levels of PFAS in the drinking water, questions remained about possible non-drinking water pathways of exposure in these communities. The Minnesota Department of Health (MDH) investigated whether PFAS in water used for yard and garden irrigation results in elevated concentrations of PFAS in soil and home-grown produce...
December 29, 2017: Chemosphere
https://www.readbyqxmd.com/read/29324382/spatial-and-temporal-distribution-of-antibiotic-resistomes-in-a-peri-urban-area-is-associated-significantly-with-anthropogenic-activities
#6
Qian Xiang, Qing-Lin Chen, Dong Zhu, Xin-Li An, Xiao-Ru Yang, Jian-Qiang Su, Min Qiao, Yong-Guan Zhu
With the rapid development of urbanization and industrialization, the peri-urban areas are often the sites for waste dumps, which may exacerbate the occurrence and spread of antibiotic resistance from waste to soil bacteria. However, the profiles of antibiotic resistomes and the associated factors influencing their dissemination in peri-urban areas have not been fully explored. Here, we characterized the antibiotic resistance genes (ARGs) in peri-urban arable and pristine soils in four seasons at the watershed scale, by using high-throughput qPCR...
January 8, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29323832/influences-of-a-church-based-intervention-on-falls-risk-among-seniors
#7
Morgan Briggs, Jeffrey A Morzinski, Julie Ellis
BACKGROUND AND OBJECTIVES: Prior studies illustrate that community-based programs effectively decrease falls risk in older adults and that faith-based programs improve health behaviors. The literature is unclear whether faith-based initiatives reduce seniors' fall risks. To tackle this gap, a long-term partnership led by 10 urban churches, a nearby nursing school, and a medical school developed a study with 3 objectives: determine baseline health concerns associated with falls (eg, depression, polypharmacy), implement a nurse-led, faith-based health education initiative for community-dwelling African American seniors at-risk of hospitalization, and assess pre- to post -program fall frequency...
August 2017: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29322861/community-mobility-after-stroke-a-systematic-review
#8
Steven Wesselhoff, Timothy A Hanke, Christian C Evans
Background Stroke is the leading cause of severe disability and many survivors report long-term physical or cognitive impairments that may impact their ability to achieve community mobility (CM). PURPOSE: To determine the extent to which people with chronic stroke achieve CM compared to age-matched norms or non-neurologically impaired controls. Methods The StrokEDGE outcome measures were searched to identify validated tools that included >25% of items addressing CM. MEDLINE, CINAHL, Google Scholar, PubMed, PEDro and the Cochrane databases were searched from 2001 to 2015 with the identified outcome measures cross-referenced against search terms related to stroke and CM...
January 11, 2018: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29321887/habitat-formation-prevails-over-predation-in-influencing-fouling-communities
#9
Jean-Charles Leclerc, Frédérique Viard
Coastal human-made structures, such as marinas and harbors, are expanding worldwide. Species assemblages described from these artificial habitats are novel relative to natural reefs, particularly in terms of the abundance of nonindigenous species (NIS). Although these fouling assemblages are clearly distinctive, the ecosystem functioning and species interactions taking place there are little understood. For instance, large predators may influence the fouling community development either directly (feeding on sessile fauna) or indirectly (feeding on small predators associated with these assemblages)...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29320542/ancient-mitogenomes-of-phoenicians-from-sardinia-and-lebanon-a-story-of-settlement-integration-and-female-mobility
#10
E Matisoo-Smith, A L Gosling, D Platt, O Kardailsky, S Prost, S Cameron-Christie, C J Collins, J Boocock, Y Kurumilian, M Guirguis, R Pla Orquín, W Khalil, H Genz, G Abou Diwan, J Nassar, P Zalloua
The Phoenicians emerged in the Northern Levant around 1800 BCE and by the 9th century BCE had spread their culture across the Mediterranean Basin, establishing trading posts, and settlements in various European Mediterranean and North African locations. Despite their widespread influence, what is known of the Phoenicians comes from what was written about them by the Greeks and Egyptians. In this study, we investigate the extent of Phoenician integration with the Sardinian communities they settled. We present 14 new ancient mitogenome sequences from pre-Phoenician (~1800 BCE) and Phoenician (~700-400 BCE) samples from Lebanon (n = 4) and Sardinia (n = 10) and compare these with 87 new complete mitogenomes from modern Lebanese and 21 recently published pre-Phoenician ancient mitogenomes from Sardinia to investigate the population dynamics of the Phoenician (Punic) site of Monte Sirai, in southern Sardinia...
2018: PloS One
https://www.readbyqxmd.com/read/29319435/black-lgb-identities-and-perceptions-of-same-sex-marriage
#11
Jess Lee
The 2015 SCOTUS ruling legalizing same-sex marriage was hailed as a universal victory for the lesbian, gay, and bisexual (LGB) community, but the pervasive support mobilized to achieve this goal may mask important dissension and inequality within the community. Specifically, how race may shape or perpetuate inequalities in the LGB community through same-sex marriage has largely been absent from the discussion. Focusing on the perceived impact of same-sex marriage in respondents' lives, I investigate the relationship between black LGBs' perception of same-sex marriage legalization and their intersectional identities and community membership...
January 10, 2018: Journal of Homosexuality
https://www.readbyqxmd.com/read/29318602/effect-of-family-planning-interventions-on-couple-years-of-protection-in-malawi
#12
Clara Lemani, Nenani Kamtuwanje, Billy Phiri, Ilene S Speizer, Kavita Singh, Olive Mtema, Ndidza Chisanu, Jennifer H Tang
OBJECTIVE: The primary objective was to assess the effect of family planning interventions at two health facilities in Malawi on couple years of protection (CYP). METHODS: A prospective quasi-experimental design was used to compare CYP and uptake of long-acting reversible contraception (LARC) between two intervention facilities (Area 25 Health Center and Kasungu District Hospital) and two nonintervention facilities (Mkanda Health Center and Dowa District Hospital)...
January 9, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29318592/falls-in-cognitively-impaired-older-adults-implications-for-risk-assessment-and-prevention
#13
Manuel Montero-Odasso, Mark Speechley
OBJECTIVES: To provide an overview of the role of cognition in falls, with potential implications for managing and preventing falls in older adults. DESIGN: Review. SETTING: Observational and interventional studies addressing the role of cognition on falls. PARTICIPANTS: Community-dwelling older adults (65 years and older). MEASUREMENTS: The relationship between gait and cognition in aging and neurodegeneration was reviewed in the medical literature to highlight the role of brain motor control deficits in fall risk...
January 10, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29317222/do-performance-measures-of-strength-balance-and-mobility-predict-quality-of-life-and-community-reintegration-after-stroke
#14
Joshua W Cohen, Tanya D Ivanova, Brenda Brouwer, Kimberly J Miller, Dianne Bryant, S Jayne Garland
OBJECTIVE: To investigate the extent to which physical performance measures of strength, balance and mobility taken at discharge from inpatient stroke rehabilitation can predict health-related quality of life (HRQoL) and community reintegration after 6 months. DESIGN: Longitudinal Study SETTING: University Laboratory PARTICIPANTS: Seventy-five adults recruited within one month following discharge home from inpatient stroke rehabilitation. Inclusion criteria were: major unilateral hemispheric stroke, English speaking, able to communicate, discharged home...
January 6, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29316983/urogenital-schistosomiasis-in-cabo-delgado-northern-mozambique-baseline-findings-from-the-score-study
#15
Anna E Phillips, Pedro H Gazzinelli-Guimarães, Herminio O Aurelio, Neerav Dhanani, Josefo Ferro, Rassul Nala, Arminder Deol, Alan Fenwick
BACKGROUND: The results presented here are part of a five-year cluster-randomised intervention trial that was implemented to understand how best to gain and sustain control of schistosomiasis through different preventive chemotherapy strategies. This paper presents baseline data that were collected in ten districts of Cabo Delgado province, northern Mozambique, before treatment. METHODS: A cross-sectional study of 19,039 individuals was sampled from 144 villages from May to September 2011...
January 10, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29316686/pharmacy-practice-and-education-in-romania
#16
Roxana Sandulovici, Constantin Mircioiu, Cristina Rais, Jeffrey Atkinson
The PHARMINE ("Pharmacy Education in Europe") project examined the organisation of pharmacy practice and education in the European Union (EU). An electronic survey was sent out to representatives of different sectors (community, hospital, industrial pharmacists, university staff, and students) in each individual EU member state. This paper presents the results of the PHARMINE survey on pharmacy practice and education in Romania. In the light of this data we examine to what extent harmonisation of practice and education with EU norms has occurred, whether this has promoted mobility of pharmacy professionals, academics and students, and what impact it has had on healthcare in Romania...
January 8, 2018: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29316201/women-s-situation-specific-strategies-in-managing-participation-restrictions-due-to-early-rheumatoid-arthritis-a-gender-comparison
#17
Gunnel Östlund, Mathilda Björk, Ingrid Thyberg, Eva Valtersson, Annette Sverker
INTRODUCTION: The present study explored how women describe their use of situation-specific strategies when managing rheumatoid arthritis (RA). The aim was also to compare women's strategies with those of men, and see the extent to which they used the same strategies. METHODS: The data were collected using semi-structured interviews based on the critical incident technique. The sample consisted of women with early rheumatic arthritis (n = 34), and the results were compared with data reported in a previous study on men (n = 25) from the same cohort...
January 9, 2018: Musculoskeletal Care
https://www.readbyqxmd.com/read/29315796/the-association-of-self-reported-diabetes-with-impaired-social-functioning-in-low-middle-and-high-income-countries-findings-from-the-world-health-survey
#18
A Loerbroks, R M Herr, A Icks, J A Bosch
AIM: Epidemiological studies from high-income countries show that diabetes is associated with impaired social functioning. As healthcare systems in middle- and low-income countries offer fewer resources to curtail the potential social impact of diabetes, we performed a comparative study on the diabetes-social impairment link in low-, middle- and high-income countries. METHODS: We use data from the cross-sectional World Health Survey (n = 235 428 from 10 low-income, 29 middle-income and 9 high-income countries)...
January 7, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29314515/looking-to-tomorrow-s-healthcare-today-a-participatory-health-perspective
#19
Sheryl Coughlin, David Roberts, Kenneth O'Neill, Peter Brooks
Health systems around the world face the issue of financial and workforce sustainability. Mobile health technologies - those devices which connect health professionals, patients, payers and the many other contributors who make up the health system offer some solutions - not just as 'add ons' but as enablers of real system change. This paper presents a vision for what the health system of the future could be like and emphasises the opportunities for real patient participation in clinical decision-making if the professions can engage the technologies and patients/community in a meaningful way...
January 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29313471/epidemiological-serological-and-virological-features-of-dengue-in-nha-trang-city-vietnam
#20
Duong Le Quyen, Nguyen Thanh Le, Cao Thi Van Anh, Nguyen Binh Nguyen, Dong Van Hoang, Jacqui L Montgomery, Simon C Kutcher, Nguyen Hoang Le, Nguyen Tran Hien, Duong Thi Hue Kien, Maia Rabaa, Scott L O'Neill, Cameron P Simmons, Dang Duc Anh, Katherine L Anders
Vietnam is endemic for dengue. We conducted a series of retrospective and prospective studies to characterize the epidemiology of dengue and population mobility patterns in Nha Trang city, Vietnam, with a view to rational design of trials of community-level interventions. A 10-year time series of dengue case notifications showed pronounced interannual variability, as well as spatial heterogeneity in ward-level dengue incidence (median annual coefficient of variation k = 0.47). Of 451 children aged 1-10 years enrolled in a cross-sectional serosurvey, almost one-third had evidence of a past dengue virus (DENV) infection, with older children more likely to have a multitypic response indicative of past exposure to ≥ 1 serotype...
January 8, 2018: American Journal of Tropical Medicine and Hygiene
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