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https://www.readbyqxmd.com/read/28303214/evidence-based-management-and-controversies-in-blunt-splenic-trauma
#1
REVIEW
D C Olthof, C H van der Vlies, J C Goslings
PURPOSE OF REVIEW: The study aims to describe the evidence-based management and controversies in blunt splenic trauma. RECENT FINDINGS: A shift from operative management to non-operative management (NOM) has occurred over the past decades where NOM has now become the standard of care in haemodynamically stable patients with blunt splenic injury. Splenic artery embolisation (SAE) is generally believed to increase the success rate of NOM. Not all the available evidence is that optimistic about SAE however...
2017: Current Trauma Reports
https://www.readbyqxmd.com/read/28262925/washout-policies-in-long-term-indwelling-urinary-catheterisation-in-adults
#2
REVIEW
Ashley J Shepherd, William G Mackay, Suzanne Hagen
BACKGROUND: People requiring long-term bladder draining with an indwelling catheter can experience catheter blockage. Regimens involving different solutions can be used to wash out catheters with the aim of preventing blockage. This is an update of a review published in 2010. OBJECTIVES: To determine if certain washout regimens are better than others in terms of effectiveness, acceptability, complications, quality of life and critically appraise and summarise economic evidence for the management of long-term indwelling urinary catheterisation in adults...
March 6, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28260769/morbidity-and-mortality-after-pancreatoduodenectomy-a-five-year-experience-in-bangabandhu-sheikh-mujib-medical-university
#3
B C Das, A S Khan, N E Elahi, M S Uddin, B C Debnath, Z R Khan
Mortality and morbidity was assessed after adoption of a systematic care for patient with pancreatoduodenectomy starting from patient selection and preparation, operative technique, and postoperative care. In this prospective study seventy patients who underwent pancreatoduodenectomy for periampullary carcinoma with curative intent between January 2010 and December 2014 were carefully analyzed prospectively. Patients were selected those who had ampullary carcinoma, lower bile duct carcinoma and small size carcinoma head of pancreas without local invasion and distant metastasis, and the patient who did not have any major disabling comorbid diseases...
January 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28244879/automated-high-dose-rate-brachytherapy-treatment-planning-for-a-single-channel-vaginal-cylinder-applicator
#4
Yuhong Zhou, Peter Klages, Jun Tan, Yujie Chi, Strahinja Stojadinovic, Ming Yang, Brian Hrycushko, Paul Medin, Arnold Pompos, Steve Jiang, Kevin Albuquerque, Xun Jia
High dose rate (HDR) brachytherapy treatment planning is conventionally performed manually and/or with aids of preplanned templates. In general the standard of care would be elevated by conducting an automated process to improve treatment planning efficiency, eliminate human error, and reduce plan quality variations. Thus, our group is developing AutoBrachy, an automated HDR brachytherapy planning suite of modules used to augment a clinical treatment planning system. This paper describes our proof-of-concept module for vaginal cylinder HDR planning that has been fully developed...
February 28, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28223945/toward-respiratory-assessment-using-depth-measurements-from-a-time-of-flight-sensor
#5
Charles Sharp, Vahid Soleimani, Sion Hannuna, Massimo Camplani, Dima Damen, Jason Viner, Majid Mirmehdi, James W Dodd
Introduction: There is increasing interest in technologies that may enable remote monitoring of respiratory disease. Traditional methods for assessing respiratory function such as spirometry can be expensive and require specialist training to perform and interpret. Remote, non-contact tracking of chest wall movement has been explored in the past using structured light, accelerometers and impedance pneumography, but these have often been costly and clinical utility remains to be defined. We present data from a 3-Dimensional time-of-flight camera (found in gaming consoles) used to estimate chest volume during routine spirometry maneuvres...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28214482/catheter-directed-ultrasound-assisted-thrombolysis-is-a-safe-and-effective-treatment-for-pulmonary-embolism-even-in-high-risk-patients
#6
Kristen A Lee, Andrew Cha, Mark H Kumar, Combiz Rezayat, Clifford M Sales
OBJECTIVE: We sought to assess the early success and safety of catheter-directed, ultrasound-assisted (CDUA) thrombolysis for acute pulmonary embolism (PE) in patients deemed to be "high risk" for thrombolytic therapy. METHODS: A retrospective evaluation of patients who underwent CDUA pulmonary thrombolysis in our practice during 39 months is reported. There were 91 patients considered, all of whom presented with acute PE as diagnosed by computed tomography angiography...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28192877/effect-of-hyperglycemia-on-brain-and-liver-18-f-fdg-standardized-uptake-value-fdg-suv-measured-by-quantitative-positron-emission-tomography-pet-imaging
#7
Benjamin L Viglianti, Ka Kit Wong, Stephanie M Wimer, Aishwarya Paraeswaran, Bin Nan, Christy Ky, Danyelle M Townsend, Domenico Rubello, Kirk A Frey, Milton D Gross
PURPOSE: Blood glucose is routinely measured prior to (18)F-fluorodeoxyglucose (FDG) administration in positron emission tomography (PET) imaging to identify hyperglycemia that may affect image quality. In this study we explore the effects of blood glucose levels upon semi-quantitative standardized uptake value (SUV) measurements of target organs and tissues of interest and in particular address the relationship of blood glucose to FDG accumulation in the brain and liver. METHODS: 436 FDG PET/CT consecutive studies performed for oncology staging in 229 patients (226 male) at the Ann Arbor Veterans Administration Healthcare System were reviewed...
April 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28181901/systematic-review-and-meta-analysis-of-the-efficacy-and-safety-of-minocycline-in-schizophrenia
#8
Marco Solmi, Nicola Veronese, Nita Thapa, Silvia Facchini, Brendon Stubbs, Michele Fornaro, André F Carvalho, Christoph U Correll
OBJECTIVE: Our aim was to perform an updated systematic review and meta-analysis on the efficacy and safety of adjunctive minocycline as a treatment of schizophrenia. METHODS: We conducted a PubMed/Scopus database search from inception to 3 February 2016 for randomized, placebo-controlled trials (RCTs), open non-randomized studies, and case reports/series evaluating minocycline in patients with schizophrenia. Random-effects meta-analysis of positive, negative, depressive, and cognitive symptom rating scales, discontinuation and adverse effects rates calculating standardized mean difference (SMD), and risk ratios±95% confidence intervals (CI 95%) were calculated...
February 9, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28176420/development-of-simulation-based-learning-program-for-improving-adherence-to-time-out-protocol-on-high-risk-invasive-procedures-outside-of-operating-room
#9
Eun Ju Jeong, Hyun Soo Chung, Jeong Yun Choi, In Sook Kim, Seong Hee Hong, Kyung Sook Yoo, Mi Kyoung Kim, Mi Yeol Won, So Yeon Eum, Young Soon Cho
The aim of this study was to develop a simulation-based time-out learning program targeted to nurses participating in high-risk invasive procedures and to figure out the effects of application of the new program on acceptance of nurses. This study was performed using a simulation-based learning predesign and postdesign to figure out the effects of implementation of this program. It was targeted to 48 registered nurses working in the general ward and the emergency department in a tertiary teaching hospital. Difference between acceptance and performance rates has been figured out by using mean, standard deviation, and Wilcoxon-signed rank test...
February 7, 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/28166774/highly-wearable-cuff-less-blood-pressure-and-heart-rate-monitoring-with-single-arm-electrocardiogram-and-photoplethysmogram-signals
#10
Qingxue Zhang, Dian Zhou, Xuan Zeng
BACKGROUND: Long-term continuous systolic blood pressure (SBP) and heart rate (HR) monitors are of tremendous value to medical (cardiovascular, circulatory and cerebrovascular management), wellness (emotional and stress tracking) and fitness (performance monitoring) applications, but face several major impediments, such as poor wearability, lack of widely accepted robust SBP models and insufficient proofing of the generalization ability of calibrated models. METHODS: This paper proposes a wearable cuff-less electrocardiography (ECG) and photoplethysmogram (PPG)-based SBP and HR monitoring system and many efforts are made focusing on above challenges...
February 6, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28143870/early-detection-of-ovarian-cancer-using-the-risk-of-ovarian-cancer-algorithm-with-frequent-ca125-testing-in-women-at-increased-familial-risk-combined-results-from-two-screening-trials
#11
Steven J Skates, Mark H Greene, Saundra S Buys, Phuong L Mai, Powel H Brown, Marion Piedmonte, Gustavo C Rodriguez, John O Schorge, Mark Sherman, Mary B Daly, Thomas J Rutherford, Wendy R Brewster, David M O'Malley, Edward E Partridge, John Boggess, Charles W Drescher, Claudine Isaacs, Andrew Berchuck, Susan M Domchek, Susan A Davidson, Robert P Edwards, Steven A Elg, Katie Wakeley, Kelly-Anne Phillips, Deborah K Armstrong, Ira R Horowitz, Carol J Fabian, Joan Walker, Patrick M Sluss, William R Welch, Lori Minasian, Nora Horick, Carol H Kasten, Susan Nayfield, David S Alberts, Dianne M Finkelstein, Karen Lu
PURPOSE: Women at familial/genetic ovarian cancer risk often undergo screening despite unproven efficacy. Research suggests each woman has her own CA125 baseline; significant increases above this level may identify cancers earlier than standard 6-12 monthly CA125>35U/mL. EXPERIMENTAL DESIGN: Data from prospective Cancer Genetics Network and Gynecologic Oncology Group trials, which screened 3,692 women (13,080 woman-screening years) with a strong breast/ovarian cancer family history or BRCA1/2 mutations, were combined to assess a novel screening strategy...
January 31, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28125524/reliability-and-validity-study-of-the-finnish-adaptation-of-scoliosis-research-society-questionnaire-version-srs-30
#12
Kati Kyrölä, Salme Järvenpää, Jari Ylinen, Jukka-Pekka Mecklin, Jussi Petteri Repo, Arja Häkkinen
STUDY DESIGN: A prospective clinical study to test and adapt a Finnish version of the Scoliosis Research Society 30 (SRS-30) questionnaire. OBJECTIVE: To perform cross-cultural adaptation and evaluate the validity of the adapted Finnish version of the SRS-30 questionnaire. SUMMARY OF BACKGROUND DATA: The SRS-30 questionnaire has proved to be a valid instrument in evaluating health-related quality of life (HRQoL) in adolescent and adult population with spine deformities in the United States...
January 25, 2017: Spine
https://www.readbyqxmd.com/read/28120467/classification-and-evaluation-strategies-of-auto-segmentation-approaches-for-pet-report-of-aapm-task-group-no-211
#13
Mathieu Hatt, John Lee, Charles R Schmidtlein, Issam El Naqa, Curtis Caldwell, Elisabetta De Bernardi, Wei Lu, Shiva Das, Xavier Geets, Vincent Gregoire, Robert Jeraj, Michael P MacManus, Osama R Mawlawi, Ursula Nestle, Andrei B Pugachev, Heiko Schöder, Tony Shepherd, Emiliano Spezi, Dimitris Visvikis, Habib Zaidi, Assen S Kirov
PURPOSE: The purpose of this educational report is to provide an overview of the present state-of-the-art PET auto-segmentation (PET-AS) algorithms and their respective validation, with an emphasis on providing the user with help in understanding the challenges and pitfalls associated with selecting and implementing a PET-AS algorithm for a particular application. APPROACH: A brief description of the different types of PET-AS algorithms is provided using a classification based on method complexity and type...
January 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28063329/determination-of-ethyl-glucuronide-in-human-hair-samples-a-multivariate-analysis-of-the-impact-of-extraction-conditions-on-quantitative-results
#14
Alexander Mueller, Hilke Jungen, Stefanie Iwersen-Bergmann, Lars Raduenz, Susanne Lezius, Hilke Andresen-Streichert
BACKGROUND: Ethyl glucuronide (EtG), a minor metabolite of ethanol, is used as a direct alcohol biomarker for the prolonged detection of ethanol consumption. Hair testing for EtG offers retrospective, long-term detection of ethanol exposition for several months and has gained practical importance in forensic and clinical toxicology. Since quantitative results of EtG hair testings are included in interpretations, a rugged quantitation of EtG in hair matrix is important. As generally known, sample preparation is critical in hair testing, and the scope of this study was on extraction of EtG from hair matrix...
December 19, 2016: Forensic Science International
https://www.readbyqxmd.com/read/27988322/a-multi-centre-evaluation-of-eleven-clinically-feasible-brain-pet-mri-attenuation-correction-techniques-using-a-large-cohort-of-patients
#15
Claes N Ladefoged, Ian Law, Udunna Anazodo, Keith St Lawrence, David Izquierdo-Garcia, Ciprian Catana, Ninon Burgos, M Jorge Cardoso, Sebastien Ourselin, Brian Hutton, Inés Mérida, Nicolas Costes, Alexander Hammers, Didier Benoit, Søren Holm, Meher Juttukonda, Hongyu An, Jorge Cabello, Mathias Lukas, Stephan Nekolla, Sibylle Ziegler, Matthias Fenchel, Bjoern Jakoby, Michael E Casey, Tammie Benzinger, Liselotte Højgaard, Adam E Hansen, Flemming L Andersen
AIM: To accurately quantify the radioactivity concentration measured by PET, emission data need to be corrected for photon attenuation; however, the MRI signal cannot easily be converted into attenuation values, making attenuation correction (AC) in PET/MRI challenging. In order to further improve the current vendor-implemented MR-AC methods for absolute quantification, a number of prototype methods have been proposed in the literature. These can be categorized into three types: template/atlas-based, segmentation-based, and reconstruction-based...
February 15, 2017: NeuroImage
https://www.readbyqxmd.com/read/27978586/-20-years-of-bilateral-cochlear-implantation-an-analysis-of-the-implanted-patients
#16
A Radeloff, M Neckel, W Shehata-Dieler, K Rak, S P Schraven, W Großmann, R Hagen
Binaural hearing is essential for localization abilities and improves the speech perception in noise. Since 20 years, bilateral cochlear implantation is routinely performed to restore binaural hearing. In this cross-sectional study, we evaluated speech perception in quiet (Freiburger monosyllables, Hochmair-Schulz-Moser (HSM) sentence test, each at 70 dB) and in noise (HSM test, signal-to-noise ratio 10 dB) in 103 out of 165 adult patients who were bilaterally implanted in Würzburg between 1995 and June 2014...
January 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/27974626/bio-compute-objects-a-step-towards-evaluation-and-validation-of-bio-medical-scientific-computations
#17
Vahan Simonyan, Jeremy Goecks, Raja Mazumder
The unpredictability of actual physical, chemical, and biological experiments due to the multitude of environmental and procedural factors is well-documented. What is systematically overlooked, however, is that computational biology algorithms are also affected by multiplicity of parameters and have no lesser volatility. The complexities of computation protocols and interpretation of outcomes is only a part of the challenge: there are also virtually no standardized and industry accepted metadata schemas for reporting the computational objects that record the parameters used for computations together with the results of computations...
December 14, 2016: PDA Journal of Pharmaceutical Science and Technology
https://www.readbyqxmd.com/read/27960229/automated-telephone-communication-systems-for-preventive-healthcare-and-management-of-long-term-conditions
#18
REVIEW
Pawel Posadzki, Nikolaos Mastellos, Rebecca Ryan, Laura H Gunn, Lambert M Felix, Yannis Pappas, Marie-Pierre Gagnon, Steven A Julious, Liming Xiang, Brian Oldenburg, Josip Car
BACKGROUND: Automated telephone communication systems (ATCS) can deliver voice messages and collect health-related information from patients using either their telephone's touch-tone keypad or voice recognition software. ATCS can supplement or replace telephone contact between health professionals and patients. There are four different types of ATCS: unidirectional (one-way, non-interactive voice communication), interactive voice response (IVR) systems, ATCS with additional functions such as access to an expert to request advice (ATCS Plus) and multimodal ATCS, where the calls are delivered as part of a multicomponent intervention...
December 14, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27938536/acute-appendicitis-should-the-laparoscopic-approach-be-proposed-as-the-gold-standard-six-year-experience-in-an-emergency-surgery-unit
#19
G Guercio, G Augello, L Licari, A Dafnomili, C Raspanti, N Bagarella, N Falco, G Rotolo, T Fontana, C Porello, G Gulotta
Acute appendicitis is common in an Emergency Surgery Unit. Although the laparoscopic approach is a method accepted for its treatment, no strong data are available for determining how many procedures must an experienced surgeon carry out for obtaining all the advantages of this technique and if this approach can become the gold standard in the activity of a general emergency unit with senior surgeons variously skilled on the basic laparoscopy. 142 patients that underwent appendectomy (90 laparoscopic, 52 conventional) for acute appendicitis were enrolled in this institutional retrospective cohort study...
July 2016: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/27930509/current-challenges-in-providing-bariatric-surgery-in-france-a-nationwide-study
#20
COMPARATIVE STUDY
Sébastien Czernichow, Michel Paita, David Nocca, Simon Msika, Arnaud Basdevant, Bertrand Millat, Anne Fagot-Campagna
Bariatric surgery is a well-accepted procedure for severe and massive obesity management. We aimed to determine trends, geographical variations, and factors influencing bariatric surgery and the choice of procedure in France in a large observational study.The Health Insurance Fund for Salaried Workers (Caisse National Assurance Maladie Travailleurs Salariés) covers about 86% of the French population. The Système National d'Information Inter-régimes de l'Assurance Maladie database contains individualized and anonymized patient data on all reimbursements for healthcare expenditure...
December 2016: Medicine (Baltimore)
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