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https://www.readbyqxmd.com/read/29753277/amyand-s-hernia-a-case-report-and-review-of-the-literature
#1
Youssef Shaban, Adel Elkbuli, Mark McKenney, Dessy Boneva
INTRODUCTION: An Amyand hernia is a rare disease where the appendix is found within an inguinal hernia sac. This rare entity is named after the French born English surgeon, Dr. Claudius Amyand. Inguinal hernias are one of the most common surgeries that a general surgeon performs with more than 20 million inguinal hernia repairs performed yearly worldwide. The incidence of finding an appendix within the hernia sac is rare, occurring in less than 1% of inguinal hernia patients and when complications arise such as inflammation, perforation, or abscess formation it becomes exceptionally rare with an incidence of about 0...
May 7, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29746395/a-liquid-chromatography-mass-spectrometry-assay-for-determination-of-perampanel-and-concomitant-antiepileptic-drugs-in-the-plasma-of-patients-with-epilepsy-compared-with-a-fluorescent-hplc-assay
#2
Ugo de Grazia, Annachiara D'Urso, Federica Ranzato, Valentina De Riva, Giorgia Contarato, Giuseppe Billo, Francesco Perini, Elisabetta Galloni
BACKGROUND: Perampanel is a novel non-competitive selective antagonist at the postsynaptic ionotropic alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (AMPA) glutamate receptor, approved as an adjunctive agent for the treatment of partial-onset seizure with or without secondary generalization and for primary generalized tonic-clonic seizure in patients with epilepsy who are at least 12 years of age. Limited information is available about the clinical utility of therapeutic drug monitoring of perampanel and therapeutic ranges are so far not established...
May 9, 2018: Therapeutic Drug Monitoring
https://www.readbyqxmd.com/read/29725594/transperitoneal-mini-laparoscopic-pyeloplasty-in-flank-position-a-safe-method-for-infants-and-young-adults
#3
Beatriz Bañuelos Marco, Tom Florian Fuller, Frank Friedersdorff, Ricardo González, Anja Lingnau
Introduction and Objectives: Open dismembered pyeloplasty has been the gold standard treatment for ureteropelvic junction obstruction in children. Laparoscopic pyeloplasty (LP) is becoming a standard procedure, but its acceptance is slow. We report our method for minilaparoscopy (MLP) in children using a tansperitoneal approach with the patient in the lateral flank decubitus which we found technically advantageous. Materials and Methods: Retrospective review of the records of 52 children and adolescents up to 18 years of age who underwent transperitoneal MLP at our institution during March 2012-October 2017 A 5 mm trocar is placed for the camera at the site of the umblicus by open technique, two 3 mm trocars placed in the upper and lower quadrants of the abdomen...
2018: Frontiers in Surgery
https://www.readbyqxmd.com/read/29719917/the-evaluation-of-bivariate-mixed-models-in-meta-analyses-of-diagnostic-accuracy-studies-with-sas-stata-and-r
#4
Felicitas Vogelgesang, Peter Schlattmann, Marc Dewey
BACKGROUND: Meta-analyses require a thoroughly planned procedure to obtain unbiased overall estimates. From a statistical point of view not only model selection but also model implementation in the software affects the results. OBJECTIVES: The present simulation study investigates the accuracy of different implementations of general and generalized bivariate mixed models in SAS (using proc mixed, proc glimmix and proc nlmixed), Stata (using gllamm, xtmelogit and midas) and R (using reitsma from package mada and glmer from package lme4)...
May 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/29688963/how-to-optimally-fit-a-hearing-aid-for-bimodal-cochlear-implant-users-a-systematic-review
#5
Jantien L Vroegop, André Goedegebure, Marc P van der Schroeff
OBJECTIVES: Bimodal hearing has shown to improve speech recognition in quiet and in noise and to improve sound localization compared with unilateral cochlear implant (CI) use alone. Fitting the CI and hearing aid (HA) separately has been described well, but HA fitting procedures for bimodal CI users are not well researched or widely accepted. The aim of the present study was to systematically review the literature on the effect of different HA fitting strategies on auditory performance in bimodal CI users...
April 20, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29688574/reliability-of-real-time-ultrasound-imaging-for-the-assessment-of-trunk-stabilizer-muscles-a-systematic-review-of-the-literature
#6
REVIEW
Morteza Taghipour, Mohammad Ali Mohseni-Bandpei, Hamid Behtash, Iraj Abdollahi, Fatemeh Rajabzadeh, Mohammad Reza Pourahmadi, Mahnaz Emami
Rehabilitative ultrasound (US) imaging is one of the popular methods for investigating muscle morphologic characteristics and dimensions in recent years. The reliability of this method has been investigated in different studies. As studies have been performed with different designs and quality, reported values of rehabilitative US have a wide range. The objective of this study was to systematically review the literature conducted on the reliability of rehabilitative US imaging for the assessment of deep abdominal and lumbar trunk muscle dimensions...
April 24, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29678766/in-silico-toxicology-protocols
#7
Glenn J Myatt, Ernst Ahlberg, Yumi Akahori, David Allen, Alexander Amberg, Lennart T Anger, Aynur Aptula, Scott Auerbach, Lisa Beilke, Phillip Bellion, Romualdo Benigni, Joel Bercu, Ewan D Booth, Dave Bower, Alessandro Brigo, Natalie Burden, Zoryana Cammerer, Mark T D Cronin, Kevin P Cross, Laura Custer, Magdalena Dettwiler, Krista Dobo, Kevin A Ford, Marie C Fortin, Samantha E Gad-McDonald, Nichola Gellatly, Véronique Gervais, Kyle P Glover, Susanne Glowienke, Jacky Van Gompel, Steve Gutsell, Barry Hardy, James S Harvey, Jedd Hillegass, Masamitsu Honma, Jui-Hua Hsieh, Chia-Wen Hsu, Kathy Hughes, Candice Johnson, Robert Jolly, David Jones, Ray Kemper, Michelle O Kenyon, Marlene T Kim, Naomi L Kruhlak, Sunil A Kulkarni, Klaus Kümmerer, Penny Leavitt, Bernhard Majer, Scott Masten, Scott Miller, Janet Moser, Moiz Mumtaz, Wolfgang Muster, Louise Neilson, Tudor I Oprea, Grace Patlewicz, Alexandre Paulino, Elena Lo Piparo, Mark Powley, Donald P Quigley, M Vijayaraj Reddy, Andrea-Nicole Richarz, Patricia Ruiz, Benoit Schilter, Rositsa Serafimova, Wendy Simpson, Lidiya Stavitskaya, Reinhard Stidl, Diana Suarez-Rodriguez, David T Szabo, Andrew Teasdale, Alejandra Trejo-Martin, Jean-Pierre Valentin, Anna Vuorinen, Brian A Wall, Pete Watts, Angela T White, Joerg Wichard, Kristine L Witt, Adam Woolley, David Woolley, Craig Zwickl, Catrin Hasselgren
The present publication surveys several applications of in silico (i.e., computational) toxicology approaches across different industries and institutions. It highlights the need to develop standardized protocols when conducting toxicity-related predictions. This contribution articulates the information needed for protocols to support in silico predictions for major toxicological endpoints of concern (e.g., genetic toxicity, carcinogenicity, acute toxicity, reproductive toxicity, developmental toxicity) across several industries and regulatory bodies...
April 17, 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29628288/assessment-of-evar-competence-validity-of-a-novel-rating-scale-evarate-in-a-simulated-setting
#8
Michael Strøm, Lars Lönn, Lars Konge, Torben V Schroeder, Hans Lindgren, Thomas Nyheim, Maarit Venermo, Bo Bech
OBJECTIVES: The aims of this study were to investigate the validity evidence for a novel procedure specific assessment tool of competence in endovascular aortic repair (EVAR) and to establish a pass/fail level for the assessment. METHODS: Computed tomography angiography data of a 55 mm in diameter infrarenal aortic aneurysm was implemented into an endovascular simulator. Twenty-three physicians with varying EVAR experiences were video-recorded when performing a standard EVAR procedure on the simulator...
April 5, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29620793/antidepressants-versus-placebo-for-panic-disorder-in-adults
#9
REVIEW
Irene Bighelli, Mariasole Castellazzi, Andrea Cipriani, Francesca Girlanda, Giuseppe Guaiana, Markus Koesters, Giulia Turrini, Toshi A Furukawa, Corrado Barbui
BACKGROUND: Panic disorder is characterised by repeated, unexpected panic attacks, which represent a discrete period of fear or anxiety that has a rapid onset, reaches a peak within 10 minutes, and in which at least four of 13 characteristic symptoms are experienced, including racing heart, chest pain, sweating, shaking, dizziness, flushing, stomach churning, faintness and breathlessness. It is common in the general population with a lifetime prevalence of 1% to 4%. The treatment of panic disorder includes psychological and pharmacological interventions...
April 5, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29596953/measuring-the-reliability-and-validity-of-the-greek-edition-of-the-diabetes-quality-of-life-brief-clinical-inventory
#10
Maria Rekleiti, Kyriakos Souliotis, Pavlos Sarafis, Maria Tsironi, Ioannis Kyriazis
BACKGROUND: The present study focuses on studying the validity and reliability of the Greek edition of DQOL-BCI. DQOL-BCI includes 15 questions-elements that are evaluated on a 5-grade scale like Likert and two general form-shapes. METHODS: The translation process was conducted in conformity with the guidelines of EuroQol group. A non-random sample of 65 people-patients diagnosed with diabetes I and II was selected. The questionnaire that was used to collect the data was the translated version of DQOL-BCI, and included the demographic characteristics of the interviewees...
March 26, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29593868/recommendations-for-active-correction-of-hypernatremia-in-volume-resuscitated-shock-or-sepsis-patients-should-be-taken-with-a-grain-of-salt-a-systematic-review
#11
REVIEW
Joseph W Quinn, Kerry Sewell, Dell E Simmons
Background: Healthcare-acquired hypernatremia (serum sodium >145 mEq/dL) is common among critically ill and other hospitalized patients and is usually treated with hypotonic fluid and/or diuretics to correct a "free water deficit." However, many hypernatremic patients are eu- or hypervolemic, and an evolving body of literature emphasizes the importance of rapidly returning critically ill patients to a neutral fluid balance after resuscitation. Objective: We searched for any randomized- or observational-controlled studies evaluating the impact of active interventions intended to correct hypernatremia to eunatremia on any outcome in volume-resuscitated patients with shock and/or sepsis...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29592801/standardised-alcohol-screening-in-primary-health-care-services-targeting-aboriginal-and-torres-strait-islander-peoples-in-australia
#12
REVIEW
M Mofizul Islam, Helen T Oni, K S Kylie Lee, Noel Hayman, Scott Wilson, Kristie Harrison, Beth Hummerston, Rowena Ivers, Katherine M Conigrave
INTRODUCTION AND AIMS: Aboriginal and Torres Strait Islander Community Controlled Health Services (ACCHSs) around Australia have been asked to standardise screening for unhealthy drinking. Accordingly, screening with the 3-item AUDIT-C (Alcohol Use Disorders Identification Test-Consumption) tool has become a national key performance indicator. Here we provide an overview of suitability of AUDIT-C and other brief alcohol screening tools for use in ACCHSs. METHODS: All peer-reviewed literature providing original data on validity, acceptability or feasibility of alcohol screening tools among Indigenous Australians was reviewed...
March 29, 2018: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/29582450/tamper-resistant-prescription-forms-for-narcotics-in-france-should-we-generalise-them
#13
Amélie Daveluy, Lucie Sauvaget, Angela Bastien, Maryse Lapeyre-Mestre, Cédric Collin, Nathalie Richard, Françoise Haramburu
In France, prescription of narcotics must be written on a tamper-resistant prescription form with specific technical particularities. Dosage and daily dose of medicines shall be written out entirely in letters. These prescription forms are also mandatory for buprenorphine, clorazepate, clonazepam, tianeptine, buccal midazolam and zolpidem owing to traffic, abuse or diversion. In 2012, to assess the use of standard and tamper-resistant prescription forms and the acceptability of the generalization of the latter to all medicines, a national opinion survey was performed, with a postal questionnaire, within 3 randomized samples of 1,500 prescribers (physicians, dentists and midwives)...
March 27, 2018: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29576419/patterns-of-care-and-outcomes-for-glioblastoma-in-patients-with-poor-performance-status
#14
Nikita Malakhov, Anna Lee, Elizabeth Garay, Daniel J Becker, David Schreiber
PURPOSE/OBJECTIVES: While treatment with tumor resection followed by chemoradiation is generally the accepted standard of care for glioblastoma (GBM), the treatment for patients with poor performance status remains uncertain. Therefore we sought to examine patterns of care and survival outcomes among patients with poor performance status utilizing a large hospital database. METHODS/MATERIALS: We queried the National Cancer Database (NCDB) for patients with GBM and Karnofsky performance status (KPS) <60 between 2010 and 2013...
March 22, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29566783/validation-and-measurement-uncertainty-assessment-of-a-microbiological-method-using-generalized-pivotal-quantity-procedure-and-monte-carlo-simulation
#15
Saad Alaoui Sossé, Taoufiq Saffaj, Bouchaib Ihssane
Recently, a novel and effective statistical tool called the uncertainty profile has been developed with the purpose of graphically assessing the validity and estimating the measurement uncertainty of analytical procedures. One way to construct the uncertainty profile is to compute the β-content, γ-confidence tolerance interval. In this study, we propose a tolerance interval based on the combination of the generalized pivotal quantity procedure and Monte-Carlo simulation. The uncertainty profile has been applied successfully in several fields...
March 22, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29564270/patients-satisfaction-regarding-family-physician-s-consultation-in-primary-healthcare-centers-of-ministry-of-health-jeddah
#16
Khalid Bawakid, Ola Abdul Rashid, Najlaa Mandoura, Hassan Bin Usman Shah, Waqar Asrar Ahmed, Adel Ibrahim
Introduction: The current study aims to assess the level of patients' satisfaction and the factors contributing to patients' satisfaction toward family physicians (FPs) consultation, visiting primary healthcare centers (PHCCs) working under Ministry of Health, Jeddah. Materials and Methods: In this cross-sectional study conducted in Jeddah from November 1, 2016 to March 1, 2017, we used consultation satisfaction questionnaire and its four subscales with standard cutoffs...
October 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29513762/are-university-rankings-useful-to-improve-research-a-systematic-review
#17
Marlo M Vernon, E Andrew Balas, Shaher Momani
INTRODUCTION: Concerns about reproducibility and impact of research urge improvement initiatives. Current university ranking systems evaluate and compare universities on measures of academic and research performance. Although often useful for marketing purposes, the value of ranking systems when examining quality and outcomes is unclear. The purpose of this study was to evaluate usefulness of ranking systems and identify opportunities to support research quality and performance improvement...
2018: PloS One
https://www.readbyqxmd.com/read/29498368/-duodenal-adenocarcinoma-a-case-report
#18
Małgorzata Stelmaszuk, Tomasz Sarosiek
The diagnosis of duodenal adenocarcinoma is still a complex gastrological and oncological problem. The described case illustrates the unusual character of the course, the reasonableness of the diagnostic procedures and the scope of the therapy undertaken. The causes of anemia, which was the first symptom of the disease, were not revealed in the tests carried out at this stage - gastroscopy, colonoscopy, with normal other basic laboratory tests. At the next episode, after 6 months from the first, the presence of a bleeding lesion within the duodenum was revealed...
February 23, 2018: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29495600/inertial-measurement-units-for-clinical-movement-analysis-reliability-and-concurrent-validity
#19
Mohammad Al-Amri, Kevin Nicholas, Kate Button, Valerie Sparkes, Liba Sheeran, Jennifer L Davies
The aim of this study was to investigate the reliability and concurrent validity of a commercially available Xsens MVN BIOMECH inertial-sensor-based motion capture system during clinically relevant functional activities. A clinician with no prior experience of motion capture technologies and an experienced clinical movement scientist each assessed 26 healthy participants within each of two sessions using a camera-based motion capture system and the MVN BIOMECH system. Participants performed overground walking, squatting, and jumping...
February 28, 2018: Sensors
https://www.readbyqxmd.com/read/29494285/assessing-indoor-air-quality-in-new-york-city-nail-salons
#20
Brian Pavilonis, Cora Roelofs, Carly Blair
Nail salons are an important business and employment sector for recent immigrants offering popular services to a diverse range of customers across the United States. However, due to the nature of nail products and services, salon air can be burdened with a mix of low levels of hazardous airborne contaminants. Surveys of nail technicians have commonly found increased work-related symptoms, such as headaches and respiratory irritation, that are consistent with indoor air quality problems. In an effort to improve indoor air quality in nail salons, the state of New York recently promulgated regulations to require increased outdoor air and "source capture" of contaminants...
May 2018: Journal of Occupational and Environmental Hygiene
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