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hidradenitis suppurativa

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https://www.readbyqxmd.com/read/29455832/diagnostic-and-therapeutic-implications-of-ultrasound-imaging-of-perianal-fistulous-tracts-in-patients-with-suspected-hidradenitis-suppurativa
#1
A Gómez-Zubiaur, F Alfageme, E Martínez-Lorenzo, G Roustán
No abstract text is available yet for this article.
February 15, 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29452717/evaluation-of-the-mobility-of-the-shoulder-and-quality-of-life-after-perforator-flaps-for-recalcitrant-axillary-hidradenitis
#2
R Nail-Barthelemy, N Stroumza, Q Qassemyar, M Delage, A Nassif, M Atlan
BACKGROUND: Hidradenitis suppurativa is a very debilitating disease, treated by antibiotics and excision. The reconstruction is usually done by secondary wound healing and/or split-thichness skin graft. The aim of this study was to evaluate the reconstruction of the axilla with local perforator flaps as a single stage surgical treatment. METHODS: This was a monocentric retrospective study conducted between November 2013 and June 2015. We included the patients with a severe axillary localization of the disease...
February 13, 2018: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/29441533/concurrent-hidradenitis-suppurativa-and-dowling-degos-disease-taken-down-a-notch
#3
J A McGrath
No abstract text is available yet for this article.
February 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29439003/impact-of-red-and-processed-meat-and-fibre-intake-on-treatment-outcomes-among-patients-with-chronic-inflammatory-diseases-protocol-for-a-prospective-cohort-study-of-prognostic-factors-and-personalised-medicine
#4
Robin Christensen, Berit L Heitmann, Karina Winther Andersen, Ole Haagen Nielsen, Signe Bek Sørensen, Mohamad Jawhara, Anette Bygum, Lone Hvid, Jakob Grauslund, Jimmi Wied, Henning Glerup, Ulrich Fredberg, Jan Alexander Villadsen, Søren Geill Kjær, Jan Fallingborg, Seyed A G R Moghadd, Torben Knudsen, Jacob Brodersen, Jesper Frøjk, Jens Frederik Dahlerup, Anders Bo Bojesen, Grith Lykke Sorensen, Steffen Thiel, Nils J Færgeman, Ivan Brandslund, Tue Bjerg Bennike, Allan Stensballe, Erik Berg Schmidt, Andre Franke, David Ellinghaus, Philip Rosenstiel, Jeroen Raes, Mette Boye, Lars Werner, Charlotte Lindgaard Nielsen, Heidi Lausten Munk, Anders Bathum Nexøe, Torkell Ellingsen, Uffe Holmskov, Jens Kjeldsen, Vibeke Andersen
INTRODUCTION: Chronic inflammatory diseases (CIDs) are frequently treated with biological medications, specifically tumour necrosis factor inhibitors (TNFi)). These medications inhibit the pro-inflammatory molecule TNF alpha, which has been strongly implicated in the aetiology of these diseases. Up to one-third of patients do not, however, respond to biologics, and lifestyle factors are assumed to affect treatment outcomes. Little is known about the effects of dietary lifestyle as a prognostic factor that may enable personalised medicine...
February 8, 2018: BMJ Open
https://www.readbyqxmd.com/read/29431201/the-in-hospital-burden-of-hidradenitis-suppurativa-in-patients-with-inflammatory-bowel-disease-a-decade-nationwide-analysis-from-2004-to-2014
#5
Alvaro J Ramos-Rodriguez, Dmitriy Timerman, Ali Khan, Lauren Bonomo, Manrup K Hunjan, Alejandro Lemor
BACKGROUND: Hidradenitis suppurativa (HS) is a chronic inflammatory disease that significantly affects the patient's quality of life. Multiple studies have shown a strong association between HS and inflammatory bowel disease (IBD). Our primary goal was to explore the in-hospital burden of HS on patients with IBD. Our secondary goal was to establish unique baseline characteristics and comorbidities of IBD patients with HS. METHODS: This was a retrospective cohort study using the National Inpatient Sample (NIS) database for the years 2004 through 2014...
February 12, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29430722/patients-affected-by-dent-disease-2-could-be-predisposed-to-hidradenitis-suppurativa
#6
Pierluigi Marzuillo, Vincenzo Piccolo, Massimo Mascolo, Andrea Apicella, Giuseppe Argenziano, Nicoletta Della Vecchia, Stefano Guarino, Emanuele Miraglia Del Giudice, Angela La Manna
Dent disease 2 (DD2) is a rare X-Linked disorder characterized by proximal tubule dysfunction. It is considered as mild variant of Lowe Syndrome (LS) and both conditions are secondary to OCRL1 gene mutations.1 Mutations in this gene drastically reduce (<10%) inositol polyphosphate 5-phosphatase (OCRL1) activity.1 This article is protected by copyright. All rights reserved.
February 11, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29417136/a-novel-severity-assessment-scoring-system-for-hidradenitis-suppurativa
#7
Schapoor Hessam, Lisa Scholl, Michael Sand, Lutz Schmitz, Sarah Reitenbach, Falk G Bechara
Importance: The variation in both clinical appearance and responses to diverse treatment options emphasize the importance of an accurate, clinically relevant, yet easy-to-use scoring system in hidradenitis suppurativa. Objective: To propose and provide validation data for the newly designed Severity Assessment of Hidradenitis Suppurativa score. Design, Setting, and Participants: We prospectively assessed disease severity using Hurley staging and the modified Hidradenitis Suppurativa Score in 355 patients referred to Ruhr-University Bochum Department of Dermatology between March 2016 and June 2017...
February 7, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29405257/complement-activation-in-hidradenitis-suppurativa-a-new-pathway-of-pathogenesis
#8
T Kanni, O Zenker, M Habel, N Riedemann, E J Giamarellos-Bourboulis
OBJECTIVE: Despite the heavy purulence observed in hidradenitis suppurativa (HS), kinetics of complement anaphylatoxins acting to prime chemotaxis of neutrophils has never been studied. Complement activation was explored in HS. METHODS: Circulating concentrations of complement factor C5a as well as of membrane attack complex C5b-9 were determined in the plasma of 54 treatment naïve patients and of 14 healthy controls as well as in the pus of seven patients. Results were correlated with Hurley stage and iHS4 score of severity...
February 6, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29403298/the-effect-of-oral-clindamycin-and-rifampicin-combination-therapy-in-patients-with-hidradenitis-suppurativa-in-singapore
#9
Harumi Ochi, Lixian Chris Tan, Hazel H Oon
Hidradenitis suppurativa (HS) is a chronic inflammatory disease of follicular occlusion characterized by abscesses, draining sinuses, and scarring. The efficacy and tolerability of combination treatment with oral clindamycin and rifampicin have previously been assessed in 4 studies including groups of Caucasian patients. Overall results are promising with reported improvement rates between 71.4% and 85.7%. In this study, we propose that combination therapy is safe and efficacious in the treatment of HS, not only among Caucasians, but also in a group of Asian patients in Singapore...
2018: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/29387752/acquired-lymphangioma-circumscriptum-of-the-genitals-in-an-individual-with-chronic-hidradenitis-suppurativa
#10
D Michael Piernick, Syed Hamzah Mahmood, Steven Daveluy
No abstract text is available yet for this article.
January 2018: JAAD Case Reports
https://www.readbyqxmd.com/read/29380349/acne-and-hidradenitis-suppurativa
#11
REVIEW
A Pink, F Anzengruber, A A Navarini
Acne and hidradenitis suppurativa (HS) both centre on hair follicles. They often occur together as part of the acne tetrad, but are found in distinct localizations. Acne is primarily defined by the presence of comedones and inflammatory lesions. However, in HS the intertriginous localization and chronicity play equally important roles for the diagnosis to the inflammatory lesions. Genetics, bacteria, environmental factors and innate inflammation have all been found to play a role in acne and/or HS. Surprisingly, there is little overlap between the findings so far...
January 30, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29380251/safety-of-adalimumab-dosed-every-week-and-every-other-week-focus-on-patients-with-hidradenitis-suppurativa-or-psoriasis
#12
Caitriona Ryan, Jeffrey M Sobell, Craig L Leonardi, Charles W Lynde, Mahinda Karunaratne, Wendell C Valdecantos, Barbara A Hendrickson
BACKGROUND: Adalimumab is approved for the treatment of hidradenitis suppurativa (HS), plaque psoriasis, and other inflammatory conditions. OBJECTIVE: Our objective was to examine the safety of adalimumab administered every other week (EOW) and every week (EW) in patients with HS and psoriasis and to investigate informative data from non-dermatologic indications. METHODS: The safety of adalimumab 40-mg EOW versus EW dosing was examined during placebo-controlled and open-label study periods in patients with HS (three studies), psoriasis (two studies), Crohn's disease (six studies), ulcerative colitis (three studies), and rheumatoid arthritis (one study)...
January 27, 2018: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/29378201/hidradenitis-suppurativa-is-associated-with-polycystic-ovary-syndrome-a-population-based-analysis-in-the-united-states
#13
Amit Garg, Erica Neuren, Andrew Strunk
Polycystic ovary syndrome (PCOS) has been linked to hidradenitis suppurativa (HS). However, evidence establishing a relationship between the two conditions is limited. We sought to determine prevalence of PCOS among HS patients and the strength of the association. We performed a cross-sectional analysis involving 22,990 HS patients using clinical data from a multi-health system analytics platform (Explorys Inc., 2017) comprising over 50 million unique patients across all census regions of the United States...
January 26, 2018: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29377079/incidence-of-diseases-primarily-affecting-the-skin-by-age-group-population-based-epidemiologic-study-in-olmsted-county-minnesota-and-comparison-with-age-specific-incidence-rates-worldwide
#14
REVIEW
Laurel L Wessman, Louise K Andersen, Mark D P Davis
Understanding the effects of age on the epidemiology of diseases primarily affecting the skin is important to the practice of dermatology, both for proper allocation of resources and for optimal patient-centered care. To fully appreciate the effect that age may have on the population-based calculations of incidence of diseases primarily affecting the skin in Olmsted County, Minnesota, and worldwide, we performed a review of all relevant Rochester Epidemiology Project-published data and compared them to similar reports in the worldwide English literature...
January 29, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29368858/a-case-of-axillary-hidradenitis-suppurativa-treated-with-topical-tacrolimus
#15
Claudio Marasca, Maria C Annunziata, Anna Masarà, Gabriella Fabbrocini
No abstract text is available yet for this article.
January 24, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29368847/a-case-of-pyoderma-gangrenosum-acne-hidradenitis-suppurativa-pash-syndrome-associated-with-diabetes-mellitus-type-1-treated-with-adalimumab
#16
Davide Fattore, Giuseppe Pistone, Maria R Bongiorno
No abstract text is available yet for this article.
January 24, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29363099/hidradenitis-suppurativa-a-review-of-pathogenesis-associations-and-management-part-2
#17
REVIEW
Dunja Ana Vekic, Geoffrey David Cains
Hidradenitis suppurativa is a chronic, painful, autoinflammatory condition resulting in nodules, abscesses and sinus tracts. We present an evidence-based review providing new understanding of the pathogenesis of hidradenitis suppurativa and associated comorbidities. By the nature of their speciality, dermatologists are uniquely positioned to investigate and treat patients.
January 23, 2018: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/29357611/growing-evidence-for-coronary-artery-disease-risk-factors-in-patients-with-severe-hidradenitis-suppurativa
#18
A D Cohen, D Zisman
No abstract text is available yet for this article.
January 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29357084/risk-factors-for-hidradenitis-suppurativa-in-patients-with-inflammatory-bowel-disease
#19
Alexis J Lukach, Melissa I Saul, Laura K Ferris, Jason M Swoger
BACKGROUND: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder characterized by recurrent nodules, abscesses, and sinus tracts that can be debilitating and significantly impair quality of life. Small studies and case reports have suggested a possible association between HS and inflammatory bowel disease (IBD). AIMS: We performed a case-control study to further characterize IBD patients with HS in terms of smoking status, BMI, sites affected by HS, IBD type and features, and IBD medication history...
January 22, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29355905/hidradenitis-suppurativa-a-review-of-pathogenesis-associations-and-management-part-1
#20
REVIEW
Dunja Ana Vekic, John Frew, Geoffrey David Cains
Hidradenitis suppurativa is a chronic, painful, autoinflammatory condition resulting in nodules, abscesses and sinus tracts. We present an evidence-based review providing new understanding of the pathogenesis of hidradenitis suppurativa and associated comorbidities. By the nature of their speciality, dermatologists are uniquely positioned to investigate and treat patients with this condition. Data collected from a subspecialty hidradenitis suppurativa clinic (N = 106) and experiences thereof are discussed in this review...
January 21, 2018: Australasian Journal of Dermatology
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