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hidradenitis suppurativa

Rachel Giesey, Gregory R Delost, Jeremy Honaker, Neil J Korman
No abstract text is available yet for this article.
November 2017: JAAD Case Reports
P T Riis, H C Ring, R Kjaersgaard Andersen, G B Jemec
BACKGROUND: Patients with hidradenitis suppurativa (HS) often report opportunistic infections such as herpes and urinary tract infections. AIM: To compare opportunistic infections in patients with HS against a group of healthy controls (HCs). METHODS: In total, 99 patients with HS and 109 HCs were recruited at random to this retrospective case-control study. We devised a questionnaire to explore the frequency of minor infections, general practitioner (GP) visits and sick days experienced during the past 6 months...
October 10, 2017: Clinical and Experimental Dermatology
Chelsea McLellan, Mia Sisic, Hazel H Oon, Jerry Tan
BACKGROUND: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with adverse physical and psychosocial impacts. The development of an HS quality-of-life measure, HS-QoL, has been recently described. OBJECTIVE: This study was designed to validate the HS-QoL. METHOD: Fifty-five patients with HS from 4 dermatology clinics completed the 30-minute online survey. Item reduction, reliability (internal consistency), and correlation analysis (to assess convergent validity) were conducted...
October 1, 2017: Journal of Cutaneous Medicine and Surgery
Guy Shalom, Meir Babaev, Tamar Freud, Shmuel Tiosano, Nadav Pam, Amir Horev, Jacob Dreiher, Daniel A Vardy, Doron Comaneshter, Arnon D Cohen
BACKGROUND: Data on the healthcare utilization of hidradenitis suppurativa (HS) patients in primary care settings are scarce. OBJECTIVE: To investigate the healthcare service utilization of patients with HS. PATIENTS AND METHODS: In a cross-sectional study, HS patients were compared with two age- and gender-matched control groups-general population enrollees of Clalit Health Services and a group of patients with psoriasis. Healthcare services data included inpatient and outpatient community clinic visits and pharmacy claims for topical and systemic treatments...
October 5, 2017: Journal of the American Academy of Dermatology
S Hessam, M Sand, T Gambichler, M Skrygan, I Rüddel, F G Bechara
BACKGROUND: A possible regulatory involvement of the interleukin (IL)-36 family in inflammatory diseases has been suggested. OBJECTIVES: To analyze the expression of IL-36α, β, γ, and the antagonistic cytokines IL-36Ra, IL-37, and IL38 in the skin of hidradenitis suppurativa (HS) patients. METHODS: Skin samples from lesional and corresponding perilesional HS skin, and from healthy controls were included in this study and analyzed by quantitative real-time RT-PCR...
October 4, 2017: British Journal of Dermatology
P Theut Riis, D M Saunte, V Sigsgaard, C Wilken, G Jemec
BACKGROUND: HS is a debilitating chronic skin disease of the hair follicle. Intense pulsed light therapy has been suggested for treatment of HS. In this letter we report a retrospective chart review of the Hidradenitis Suppurativa patients we have treated so far. MATERIAL AND METHOD: Twenty-five patients were treated with the Palomar LuxY IPL. Patients were treated with a pulse width of either 20 or 100 nm, using a fluence between 18 and 34 J/cm(2) depending on the area treated, pain response and skin type...
October 3, 2017: Journal of Dermatological Treatment
Derek Jones, Anirban Banerjee, Peter Z Berger, Alexandra Gross, Sean McNish, Richard Amdur, Victoria K Shanmugam
Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory disease of apocrine gland-bearing skin which affects approximately 1-4% of the population. Defective keratinocyte function has been postulated to play a role in HS pathogenesis. Using an in vitro scratch assay, differences between normal, HS, and chronic wound (CW) keratinocytes were evaluated. Normal keratinocytes exhibited faster scratch closure than HS or CW, with normal samples showing 93.8% closure at 96 hours compared to 80.8% in HS (p = 0...
October 3, 2017: Immunological Investigations
Łukasz Matusiak, Justyna Szczęch, Karolina Kaaz, Edyta Lelonek, Jacek C Szepietowski
A growing body of research has indicated that pruritus is an important feature of hidradenitis suppurativa (HS). This study evaluated pruritus and pain among 103 patients with HS. Pruritus and pain intensity were assessed with a visual analogue scale, numerical rating scale and 4-item Itch Questionnaire. Dermatology Life Quality Index (DLQI) was implemented to assess quality of life (QoL) issues. Various clinical features and factors influencing pruritus were also examined. Pruritus and pain during the last week were reported among 41...
October 3, 2017: Acta Dermato-venereologica
Marion Fauconier, Ziad Reguiai, Coralie Barbe, Alban Colosio, Jean-Paul Eschard, Jean-Hugues Salmon, Guillaume Direz
OBJECTIVES: We aimed to investigate the existence of an association between hidrosadenitis suppurativa and spondyloarthritis. METHODS: We performed a single-centre, cross-sectional study in patients with hidrosadenitis suppurativa followed in a tertiary care center, and in healthy volunteers without dermatological disease, matched for age (±5 years) and gender. For each subject included, clinical examinations, HLA-B27 testing and sacro-iliac MRI were performed in order to diagnose spondyloarthritis according to the Assessment of SpondyloArthritis international Society (ASAS) criteria...
September 28, 2017: Joint, Bone, Spine: Revue du Rhumatisme
Daniel J No, Mina Amin, Jashin J Wu
No abstract text is available yet for this article.
August 2017: Cutis; Cutaneous Medicine for the Practitioner
A Garg, V Papagermanos, M Midura, A Strunk
BACKGROUND: The relationship between tobacco use and hidradenitis suppurativa (HS) is controversial. OBJECTIVE: To determine incidence of HS among tobacco smokers. METHODS: Retrospective cohort analysis identifying incident HS cases among adult tobacco smokers and non-smokers sampled from a demographically heterogeneous population-based sample of over 50 million unique patients across all census regions. RESULTS: We identified 3,924,310 tobacco smokers, among whom were 7,860 patients newly diagnosed with HS...
September 27, 2017: British Journal of Dermatology
Amit Garg, Jonathan Lavian, Andrew Strunk
BACKGROUND: There are limited data evaluating the utilization of dermatologists for the care of patients with hidradenitis suppurativa. OBJECTIVE: To determine the utilization of the dermatology ambulatory encounter among hidradenitis suppurativa patients, and to evaluate whether utilization varies by insurance status. METHODS: This was a retrospective cohort analysis in an adult population sample of 42,030 hidradenitis suppurativa patients with either private or public health insurance who were identified by a validated scheme using SNOMED-CT terminology...
September 28, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
Afsaneh Alavi, R Gary Sibbald, Robert S Kirsner
No abstract text is available yet for this article.
September 27, 2017: Journal of Dermatological Treatment
Lyn C Guenther, Rod Kunynetz, Charles W Lynde, R Gary Sibbald, John Toole, Ronald Vender, Catherine Zip
BACKGROUND: Acitretin has been used for the treatment of severe psoriasis for over 20 years. OBJECTIVE: The current project was conceived to optimise patient care by recognising the role acitretin can play in the treatment of patients with psoriasis and those with other disorders of keratinisation. METHODS: A literature review was conducted to explore the role of acitretin and to assess its value for dermatologic disorders other than severe psoriasis...
September 1, 2017: Journal of Cutaneous Medicine and Surgery
Linnea Thorlacis, Arnon D Cohen, Gunnar H Gislason, Gregor B E Jemec, Alexander Egeberg
Patients with skin disorders are considered at a higher risk of depression and anxiety than the background population. Patients with hidradenitis suppurativa (HS) may be particularly affected. We explored the association between HS and depression, anxiety, and completed suicides in the Danish national registries expanding to include data on suicidal behavior, using both a cross-sectional and a cohort study design. Both designs included 7,732 patients with HS and a background population of 4,354,137. The cohort study revealed that HS-patients had an increased risk of completed suicide after adjustment for confounding factors (11/7,732 vs...
September 20, 2017: Journal of Investigative Dermatology
Peter Theut Riis, Ditte Marie Saunte, Farida Benhadou, Veronique Del Marmol, Philippe Guillem, Moetaz El-Domyati, Hossam Abdel-Wahab, Christina Antoniou, Clio Dessinioti, Mehmet Ali Gürer, Burcu Beksaç, Jacek C Szepietowski, Lukasz Matusiak, Lennart Emtestam, Jan Lapins, Hassan Riad, Nejib Doss, António F Massa, Iltefat Hamzavi, Cynthia Nicholson, Mateja Dolenc-Voljc, Kyu Han Kim, Jungyoon Ohn, Christos C Zouboulis, Ioannis Karagiannidis, Zrinka Bukvic Mokos, Paola Durinec, Gregor B E Jemec
INTRODUCTION: Overweight is a well established risk factor for Hidradenitis Suppurativa (HS). In this cross sectional study, we compare HS patients with a high body mass index (BMI) with HS patients with a low BMI to investigate differences in disease characteristics. MATERIALS AND METHOD: Patients were recruited from 17 dermatological centers from 4 continents. A total of 246 patients with a BMI below 25 were compared to 205 patients with a BMI of above 35. RESULTS: Patients with a high BMI suffered more severe disease (Hurley, physician global assessment, number of areas affected and patient reported severity, p < 0...
September 21, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
L Emtestam, K Sartorius
No abstract text is available yet for this article.
September 2017: British Journal of Dermatology
Jessica E Kalen, Divya Shokeen, Mona Mislankar, Michael Wangia, Kiran Motaparthi
Langerhans cell histiocytosis (LCH) is an uncommon histiocytic disorder in adults. Clinically, this rare entity can mimic other dermatologic conditions, including hidradenitis suppurativa. A case of LCH is reported with clinical and histologic features of hidradenitis suppurativa, along with a review of these unusual findings. Clinical dermatologists and dermatopathologists benefit from awareness of this unique presentation, which may prompt earlier identification and diagnosis of adult patients with LCH.
September 11, 2017: American Journal of Dermatopathology
Catriona Gallagher, Shivashini Kirthi, Thomas Burke, Donal O'Shea, Anne-Marie Tobin
No abstract text is available yet for this article.
September 2017: JAAD Case Reports
Angelique Rondags, Gilles F Diercks, Paul M N Werker, Marcel F Jonkman, Barbara Horváth
No abstract text is available yet for this article.
September 2017: JAAD Case Reports
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