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"Chronic Fatigue Syndrome"

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https://www.readbyqxmd.com/read/28186393/chronic-fatigue-in-ehlers-danlos-syndrome-hypermobile-type
#1
Alan Hakim, Inge De Wandele, Chris O'Callaghan, Alan Pocinki, Peter Rowe
Chronic fatigue is an important contributor to impaired health-related quality of life in Ehlers-Danlos syndrome. There is overlap in the symptoms and findings of EDS and chronic fatigue syndrome. A proportion of those with CFS likely have EDS that has not been identified. The evaluation of chronic fatigue in EDS needs to include a careful clinical examination and laboratory testing to exclude common causes of fatigue including anemia, hypothyroidisim, and chronic infection, as well as dysfunction of major physiological or organ systems...
February 10, 2017: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/28183406/long-term-economic-evaluation-of-cognitive-behavioural-group-treatment-versus-enhanced-usual-care-for-functional-somatic-syndromes
#2
Andreas Schröder, Eva Ørnbøl, Jens S Jensen, Michael Sharpe, Per Fink
OBJECTIVE: Patients with functional somatic syndromes (FSS) such as fibromyalgia and chronic fatigue syndrome have a poor outcome and can incur high healthcare and societal costs. We aimed to compare the medium-term (16months) cost-effectiveness and the long-term (40months) economic outcomes of a bespoke cognitive-behavioural group treatment (STreSS) with that of enhanced usual care (EUC). METHODS: We obtained complete data on healthcare and indirect costs (i.e...
March 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28162843/a-sociological-stance-on-fatigue-and-tiredness-social-inequalities-norms-and-representations
#3
Marc Loriol
Fatigue is complex, representing simultaneously a physiological, psychological and social phenomenon. The sociological approach attempts to understand the experience of fatigue and its characterization at diverse periods and in various social contexts. After giving a sociological history of different forms of fatigue through the ages (acedia, melancholy, neurasthenia, chronic fatigue syndrome, etc.), this article proposes a social epidemiology of fatigue in the current period. Objectification of working and living conditions allows us to illustrate social inequalities in fatigue and exhaustion, but seems to contradict dominant social representations of fatigue today...
February 2, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28162719/-470-effects-of-lidocaine-injections-on-overall-fatigue-in-patients-with-chronic-fatigue-syndrome
#4
R Staud, J Boissoneault, D Price, M Robinson
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162483/-254-altered-resting-state-functional-connectivity-is-correlated-with-fatigue-and-pain-in-patients-with-chronic-fatigue-syndrome
#5
J Boissoneault, J Letzen, A O'Shea, S Lai, M Robinson, R Staud
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28143516/important-factors-to-consider-when-treating-children-with-chronic-fatigue-syndrome-myalgic-encephalomyelitis-cfs-me-perspectives-of-health-professionals-from-specialist-services
#6
Roxanne M Parslow, Alison Shaw, Kirstie L Haywood, Esther Crawley
BACKGROUND: Paediatric Chronic Fatigue Syndrome (CFS)/Myalgic Encephalomyelitis (ME) is relatively common and disabling. Improving treatment requires the development of Patient Reported Outcome Measures (PROMs) that enable clinicians and researchers to collect patient-centred evidence on outcomes. Health professionals are well placed to provide clinical insight into the condition, its treatment and possible outcomes. This study aimed to understand the perspectives of specialist paediatric CFS/ME health professionals and identify outcomes that are clinically important...
February 1, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28129956/-medically-unexplained-symptoms-care-in-internal-medicine-a-paradigm-of-doctor-patient-relationship-in-situation-of-uncertainty
#7
B Ranque, O Nardon
Medically unexplained symptoms (MUS) are extremely common in general practice as in all medical specialties, but their designation is not unambiguous and the approaches to take care of the patients differ from conventional therapeutic approaches. The difficulty is not to confirm the diagnosis, which is rapidly obvious with some experience, but to establish a genuinely human therapeutic relationship, without any technical help, which pushes the doctor to the edge of his empathy and communication skills. The discomfort or even distress regularly encountered by physicians in front of a patient with MUS shows that the foundations of the doctor-patient relationship under uncertainty are poorly mastered...
January 24, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28129747/giardia-specific-cellular-immune-responses-in-post-giardiasis-chronic-fatigue-syndrome
#8
Kurt Hanevik, Einar Kristoffersen, Kristine Mørch, Kristin Paulsen Rye, Steinar Sørnes, Staffan Svärd, Øystein Bruserud, Nina Langeland
BACKGROUND: The role of pathogen specific cellular immune responses against the eliciting pathogen in development of post-infectious chronic fatigue syndrome (PI-CFS) is not known and such studies are difficult to perform. The aim of this study was to evaluate specific anti-Giardia cellular immunity in cases that developed CFS after Giardia infection compared to cases that recovered well. Patients reporting chronic fatigue in a questionnaire study three years after a Giardia outbreak were clinically evaluated five years after the outbreak and grouped according to Fukuda criteria for CFS and idiopathic chronic fatigue...
January 28, 2017: BMC Immunology
https://www.readbyqxmd.com/read/28126717/reply-to-roerink-et-al-metabolomics-of-chronic-fatigue-syndrome
#9
Robert K Naviaux, Eric Gordon
No abstract text is available yet for this article.
February 7, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28116577/mechanisms-explaining-muscle-fatigue-and-muscle-pain-in-patients-with-myalgic-encephalomyelitis-chronic-fatigue-syndrome-me-cfs-a-review-of-recent-findings
#10
REVIEW
Morris Gerwyn, Michael Maes
PURPOSE OF REVIEW: Here, we review potential causes of muscle dysfunction seen in many patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) such as the effects of oxidative and nitrosative stress (O&NS) and mitochondrial impairments together with reduced heat shock protein production and a range of metabolic abnormalities. RECENT FINDINGS: Several studies published in the last few years have highlighted the existence of chronic O&NS, inflammation, impaired mitochondrial function and reduced heat shock protein production in many patients with ME/CFS...
January 2017: Current Rheumatology Reports
https://www.readbyqxmd.com/read/28113140/simultaneous-determination-of-multiple-bioactive-components-of-bu-zhong-yi-qi-tang-in-rat-tissues-by-lc-ms-ms-application-to-a-tissue-distribution-study
#11
Min He, Wenwen Chen, Mengmeng Wang, Yu Wu, Jin Zeng, Zhirong Zhang, Shujiao Shen, Jian Jiang
A liquid chromatography coupled with electrospray ionization mass spectrometry method was developed and validated for simultaneous determination of seven bioactive constituents including astragaloside IV, calycosin, glycyrrhizic acid, enoxolone, saikosaponin D, ferulic acid and hesperiden in rats' various tissues using diclofenac as the internal standard (IS). Biological samples were pretreated by protein precipitation with acetonitrile. The chromatographic separation was carried out on a C18 column with a gradient mobile phase consisting of acetonitrile and water (containing 0...
January 18, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28112075/heterogeneity-in-chronic-fatigue-syndrome-empirically-defined-subgroups-from-the-pace-trial
#12
T E Williams, T Chalder, M Sharpe, P D White
BACKGROUND: Chronic fatigue syndrome is likely to be a heterogeneous condition. Previous studies have empirically defined subgroups using combinations of clinical and biological variables. We aimed to explore the heterogeneity of chronic fatigue syndrome. METHOD: We used baseline data from the PACE trial, which included 640 participants with chronic fatigue syndrome. Variable reduction, using a combination of clinical knowledge and principal component analyses, produced a final dataset of 26 variables for 541 patients...
January 23, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28111818/dietary-and-nutrition-interventions-for-the-therapeutic-treatment-of-chronic-fatigue-syndrome-myalgic-encephalomyelitis-a-systematic-review
#13
REVIEW
N Campagnolo, S Johnston, A Collatz, D Staines, S Marshall-Gradisnik
BACKGROUND: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is characterised by unexplained fatigue for at least 6 months accompanied by a diverse but consistent set of symptoms. Diet modification and nutritional supplements could be used to improve patient outcomes, such fatigue and quality of life. We reviewed and discussed the evidence for nutritional interventions that may assist in alleviating symptoms of CFS/ME. METHODS: Medline, Cinahl and Scopus were systematically searched from 1994 to May 2016...
January 22, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/28107894/heart-rate-variability-biofeedback-therapy-and-graded-exercise-training-in-management-of-chronic-fatigue-syndrome-an-exploratory-pilot-study
#14
Petra Windthorst, Nazar Mazurak, Marvin Kuske, Arno Hipp, Katrin E Giel, Paul Enck, Andreas Nieß, Stephan Zipfel, Martin Teufel
OBJECTIVE: Chronic fatigue syndrome (CFS) is characterised by persistent fatigue, exhaustion, and several physical complaints. Research has shown cognitive behavioural therapy (CBT) and graded exercise training (GET) to be the most effective treatments. In a first step we aimed to assess the efficacy of heart rate variability biofeedback therapy (HRV-BF) as a treatment method comprising cognitive and behavioural strategies and GET in the pilot trial. In a second step we aimed to compare both interventions with regard to specific parameters...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28107891/telephone-administered-versus-live-group-cognitive-behavioral-stress-management-for-adults-with-cfs
#15
Daniel L Hall, Emily G Lattie, Sara F Milrad, Sara Czaja, Mary Ann Fletcher, Nancy Klimas, Dolores Perdomo, Michael H Antoni
OBJECTIVE: Chronic fatigue syndrome (CFS) symptoms have been shown to be exacerbated by stress and ameliorated by group-based psychosocial interventions such as cognitive behavioral stress management (CBSM). Still, patients may have difficulty attending face-to-face groups. This study compared the effects of a telephone-delivered (T-CBSM) vs a live (L-CBSM) group on perceived stress and symptomology in adults with CFS. METHODS: Intervention data from 100 patients with CFS (mean age 50years; 90% female) participating in T-CBSM (N=56) or L-CBSM (N=44) in previously conducted randomized clinical trials were obtained...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28104625/natural-course-of-chronic-fatigue-syndrome-myalgic-encephalomyelitis-in-adolescents
#16
Tom Norris, Simon M Collin, Kate Tilling, Roberto Nuevo, Stephen A Stansfeld, Jonathan Ac Sterne, Jon Heron, Esther Crawley
OBJECTIVE: Little is known about persistence of or recovery from chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in adolescents. Previous studies have small sample sizes, short follow-up or have focused on fatigue rather than CFS/ME or, equivalently, chronic fatigue, which is disabling. This work aimed to describe the epidemiology and natural course of CFS/ME in adolescents aged 13-18 years. DESIGN: Longitudinal follow-up of adolescents enrolled in the Avon Longitudinal Study of Parents and Children...
January 19, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28098051/chronic-fatigue-syndrome-cognitive-behavioural-and-emotional-processing-vulnerability-factors
#17
Samantha K Brooks, Trudie Chalder, Katharine A Rimes
BACKGROUND: Cognitive-behavioural models of chronic fatigue syndrome (CFS) suggest that personality factors such as perfectionism and high moral standards may contribute to the development of CFS. AIMS: To investigate cognitive, behavioural and emotional processing risk factors for CFS. METHOD: CFS patients (n = 67) at a UK specialist clinic completed questionnaires about psychological characteristics both currently and retrospectively (6 months pre-CFS onset)...
January 18, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28089639/a-systematic-review-of-the-association-between-fatigue-and-genetic-polymorphisms
#18
REVIEW
Tengteng Wang, Jie Yin, Andrew H Miller, Canhua Xiao
Fatigue is one of the most common and distressing symptoms, leading to markedly decreased quality of life among a large subset of patients with a variety of disorders. Susceptibility to fatigue may be influenced by genetic factors including single nucleotide polymorphisms (SNPs), especially in the regulatory regions, of relevant genes. To further investigate the association of SNPs with fatigue in various patient populations, a systematic search was conducted on Pubmed, CINAHL, PsycINFO, and Sociological Abstracts Database for fatigue related-terms in combination with polymorphisms or genetic variation-related terms...
January 12, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28087544/children-s-experiences-of-chronic-fatigue-syndrome-myalgic-encephalomyelitis-cfs-me-a-systematic-review-and-meta-ethnography-of-qualitative-studies
#19
Roxanne M Parslow, Sarah Harris, Jessica Broughton, Adla Alattas, Esther Crawley, Kirstie Haywood, Alison Shaw
OBJECTIVE: To synthesis the qualitative studies of children's experiences of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). DESIGN: Systematic review and meta-ethnography. BACKGROUND: CFS/ME is an important disabling illness, with uncertain cause and prognosis. As a result, children with CFS/ME can find themselves living with greater uncertainty and stigma, exacerbating the impact of the condition. There is a growing body of qualitative research in CFS/ME, yet there has been no attempt to systematically synthesis the studies involving children...
January 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28059425/metabolic-profiling-of-a-myalgic-encephalomyelitis-chronic-fatigue-syndrome-discovery-cohort-reveals-disturbances-in-fatty-acid-and-lipid-metabolism
#20
Arnaud Germain, David Ruppert, Susan M Levine, Maureen R Hanson
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) remains a continuum spectrum disease without biomarkers or simple objective tests, and therefore relies on a diagnosis from a set of symptoms to link the assortment of brain and body disorders to ME/CFS. Although recent studies show various affected pathways, the underlying basis of ME/CFS has yet to be established. In this pilot study, we compare plasma metabolic signatures in a discovery cohort, 17 patients and 15 matched controls, and explore potential metabolic perturbations as the aftermath of the complex interactions between genes, transcripts and proteins...
January 6, 2017: Molecular BioSystems
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