keyword
MENU ▼
Read by QxMD icon Read
search

Dolor

keyword
https://www.readbyqxmd.com/read/29469785/p%C3%A3-nfigo-foli%C3%A3-ceo-agravado-por-f%C3%A3-rmacos-en-un-paciente-con-psoriasis-con-buena-respuesta-a-adalimumab
#1
Jimena Sanz-Bueno, Elena Gallo, Dolores Caro-Gutiérrez, Araceli Sánchez-Gilo, Marta Gutiérrez Pascual, Laura Rojas-Scheffer, Francisco Javier Vicente-Martín
El pénfigo foliáceo es una enfermedad autoinmune ampollosa debida a la producción de autoanticuerpos frente a la desmogleína 1. Presentamos el caso de un paciente con psoriasis y pénfigo foliáceo agravado por enalapril y amlodipino, con buena respuesta de ambas patologías a la terapia con adalimumab.Pemphigus foliaceus is a blistering autoimmune disease related to the production of autoantibodies against desmoglein 1. We present a patient with psoriasis and pemphigus foliaceus aggravated by enalapril and amlodipine intake, with successful response of both conditions to adalimumab therapy...
October 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29468900/health-promotion-in-young-people-identifying-the-predisposing-factors-of-self-care-health-habits
#2
Estefanía Ruiz-Palomino, Cristina Giménez-García, Rafael Ballester-Arnal, María Dolores Gil-Llario
Unhealthy behaviors are strongly associated with chronic diseases, disabilities, or mortality. Identifying the predisposing factors that influence on self-care healthy habits will improve an early detection of high-risk groups. Four hundred and sixty-six Spanish young people aged 18-25 years were assessed. Global perceived health self-care was predicted by Value of health and Conscientiousness, both in females ( R2  = 0.185; F = 29.661; p < 0.001) and males ( R2  = 0.154; F = 17.849; p < 0...
February 1, 2018: Journal of Health Psychology
https://www.readbyqxmd.com/read/29466706/identification-and-characterization-of-taenia-solium-enolase-as-a-plasminogen-binding-protein
#3
Dolores A Ayón-Núñez, Gladis Fragoso, Clara Espitia, Martín García-Varela, Xavier Soberón, Gabriela Rosas, Juan P Laclette, Raúl J Bobes
The larval stage of Taenia solium (cysticerci) is the causal agent of human and swine cysticercosis. When ingested by the host, T. solium eggs are activated and hatch in the intestine, releasing oncospheres that migrate to various tissues and evolve into cysticerci. Plasminogen (Plg) receptor proteins have been reported to play a role in migration processes for several pathogens. This work is aimed to identify Plg-binding proteins in T. solium cysticerci and determine whether T. solium recombinant enolase (rTsEnoA) is capable of specifically binding and activating human Plg...
February 18, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29466646/estimation-of-genetic-variation-in-closely-related-cycad-species-in-ceratozamia-zamiaceae-cycadales-using-rapds-markers
#4
Miguel A Pérez-Farrera, Andrew P Vovides, Dolores González, Sergio López, Luis Hernandez-Sandoval, Mahinda Martínez
The Ceratozamia norstogii complex from Southern Mexico is made up of four closely related taxa and occurs in similar habitats (Quercus forest). All have linear-lanceolate leaflets with great similarity between them, especially in juvenile stages, but differentiate with age. There has been debate regarding delimitation of species due to character loss in herbarium specimens. The aim of this study was to determine the genetic variation, and to measure genetic similarity between the four taxa. We studied populations in Cintalapa (Chiapas) for C...
March 2017: Revista de Biología Tropical
https://www.readbyqxmd.com/read/29466454/interaction-between-fkbp5-variability-and-recent-life-events-in-the-anxiety-spectrum-evidence-for-the-differential-susceptibility-model
#5
Beatriz Pérez-Pérez, Paula Cristóbal-Narváez, Tamara Sheinbaum, Thomas R Kwapil, Sergi Ballespí, Elionora Peña, Marta de Castro-Catala, Maria Dolors Riba, Araceli Rosa, Neus Barrantes-Vidal
BACKGROUND: Gene-environment interaction (GxE) research has highlighted the importance of investigating the FK506 binding protein 51 (FKBP5) gene as a sensitivity gene. However, previous GxE studies with FKBP5 have not measured the full environmental spectrum or applied statistical tests to discern whether the GxE interaction fits better with the differential-susceptibility or diathesis-stress hypotheses. This study examined whether single nucleotide polymorphisms (SNPs) on FKBP5 gene moderate the association of positive and negative recent life events (LEs) with depressive symptoms, state-anxiety, neuroticism, and social anxiety traits...
2018: PloS One
https://www.readbyqxmd.com/read/29464948/inhibition-of-oral-pathogens-adhesion-to-human-gingival-fibroblasts-by-wine-polyphenols-alone-and-in-combination-with-an-oral-probiotic
#6
Adelaida Esteban-Fernández, Irene Zorraquín-Peña, Maria D Ferrer, Alex Mira, Begoña Bartolomé, Dolores González de Llano, M Victoria Moreno-Arribas
Several benefits have been described for red wine polyphenols and probiotic strains in the promotion of colonic metabolism and health. On the contrary, knowledge about their role in the management of oral health is still scarce. In this work, the antiadhesive capacity of selected red wine polyphenols and oenological extracts against the oral pathogens Porphyromonas gingivalis, Fusobacterium nucleatum, and Streptococcus mutans in an in vitro model of human gingival fibroblasts has been explored as well as their complementary action with the candidate oral probiotic Streptococcus dentisani...
February 21, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29463841/chaotic-dynamics-of-inner-ear-hair-cells
#7
Justin Faber, Dolores Bozovic
Experimental records of active bundle motility are used to demonstrate the presence of a low-dimensional chaotic attractor in hair cell dynamics. Dimensionality tests from dynamic systems theory are applied to estimate the number of independent variables sufficient for modelling the hair cell response. Poincaré maps are constructed to observe a quasiperiodic transition from chaos to order with increasing amplitudes of mechanical forcing. The onset of this transition is accompanied by a reduction of Kolmogorov entropy in the system and an increase in transfer entropy between the stimulus and the hair bundle, indicative of signal detection...
February 20, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29462159/factors-associated-with-occasional-and-recurrent-falls-in-mexican-community-dwelling-older-people
#8
Marcela Agudelo-Botero, Liliana Giraldo-Rodríguez, Juana Catalina Murillo-González, Dolores Mino-León, Esteban Cruz-Arenas
Falls are a frequent event among older adults that can cause wounds, disability, psychological disorders, and premature death. Although the large number of existing studies on the issue, few have been conducted in middle- and low-income countries. The objective of the present study is to identify the sociodemographic, medical, and functional performance factors associated with occasional and recurrent falls in Mexican older adults dwelling in community. Cross-sectional analysis of 9 598 adults ≥60 years old who participated in the fourth round (2015) of the Mexican Health and Aging Study...
2018: PloS One
https://www.readbyqxmd.com/read/29461907/personalizing-patients-advance-directives-decreases-the-willingness-of-intensive-care-unit-residents-to-stop-treatment-a-randomized-study
#9
Stéphane Jouffre, Joanne Ghazal, René Robert, Jean Reignier, Dolores Albarracín
BACKGROUND: While following patients' advance directives (ADs) is legally binding, French physicians in Intensive Care Unit (ICU) perceive them as complicating their decision. Decision making and ICU residents benefit from personalizing the dying process. In France, ADs can include personal information. OBJECTIVE: Whether personalizing ADs affects ICU residents' decisions and perception of the patient. SUBJECTS AND DESIGN: Sixty-six ICU residents assigned to three experimental groups and presented with a case file for an ICU patient...
February 20, 2018: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/29461875/assessing-adherence-to-inhaled-medication-in-asthma-impact-of-once-daily-versus-twice-daily-dosing-frequency-the-ataud-study
#10
Luis Pérez de Llano, Abel Pallares Sanmartin, Francisco Javier González-Barcala, Mar Mosteiro-Añón, Dolores Corbacho Abelaira, Raquel Dacal Quintas, María Merino Ventosa
INTRODUCTION: This study was aimed at evaluating whether once-daily regimens (od-r) show benefits in adherence when compared to twice-daily (td-r). METHODS: Prospective, multicenter, 6-month follow-up study with two visits. The main objective was to compare adherence assessed by the electronic prescription refill rate (EPRR) and by the 10-item Test of Adherence to Inhalers (TAI) in patients with od-r and td-r. Suboptimal adherence was defined as TAI < 50 or EPRR ≤ 80%...
February 20, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29460698/-life-goes-on-everyday-tasks-coping-self-efficacy-and-independence-exploring-older-adults-recovery-from-hip-fracture
#11
Dolores Langford, Nicola Edwards, Samantha M Gray, Lena Fleig, Maureen C Ashe
Older adults face many challenges in the first few months after hip fracture. Rehabilitation holds promise to assist the recovery process. Therefore, we used semistructured interviews to explore older adults' and allied health professionals' acceptance of a rehabilitation intervention for hip fracture, and we described perceptions of the early recovery period (<4 months). Interviews were recorded and transcribed verbatim; three authors independently read the transcripts multiple times and together developed themes guided by Interpretive Description...
February 1, 2018: Qualitative Health Research
https://www.readbyqxmd.com/read/29459374/rescue-of-learning-and-memory-deficits-in-the-human-non-syndromic-intellectual-disability-cereblon-knockout-mouse-model-by-targeting-the-ampk-mtorc1-translational-pathway
#12
Charlotte C Bavley, Richard C Rice, Delaney K Fischer, Amanda K Fakira, Maureen Byrne, Maria Kosovsky, Bryant K Rizzo, Dolores Del Prete, Armin Alaedini, Jose A Morón, Joseph J Higgins, Luciano D'Adamio, Anjali M Rajadhyaksha
A homozygous nonsense mutation in the cereblon ( CRBN ) gene results in autosomal recessive, non-syndromic intellectual disability (ARNSID) that is devoid of other phenotypic features, suggesting a critical role of CRBN in mediating learning and memory. In this study, we demonstrate that adult male Crbn knockout ( Crbn KO ) mice exhibit deficits in hippocampal-dependent learning and memory tasks that are recapitulated by focal knockout of Crbn in the adult dorsal hippocampus, with no changes in social or repetitive behavior...
February 19, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29456532/a-stretch-of-negatively-charged-amino-acids-of-linker-for-activation-of-t-cell-adaptor-has-a-dual-role-in-t-cell-antigen-receptor-intracellular-signaling
#13
Mikel M Arbulo-Echevarria, Isaac Narbona-Sánchez, Cecilia M Fernandez-Ponce, Inmaculada Vico-Barranco, Mª Dolores Rueda-Ygueravide, Michael L Dustin, Arkadiusz Miazek, Mª Carmen Duran-Ruiz, Francisco García-Cózar, Enrique Aguado
The adaptor protein linker for activation of T cells (LAT) has an essential role transducing activatory intracellular signals coming from the TCR/CD3 complex. Previous reports have shown that upon T-cell activation, LAT interacts with the tyrosine kinase Lck, leading to the inhibition of its kinase activity. LAT-Lck interaction seemed to depend on a stretch of negatively charged amino acids in LAT. Here, we have substituted this segment of LAT between amino acids 113 and 126 with a non-charged segment and expressed the mutant LAT (LAT-NIL) in J...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29456457/effect-of-ovarian-cancer-ascites-on-skov-3-cells-proteome-new-proteins-associated-with-aggressive-phenotype-in-epithelial-ovarian-cancer
#14
Alfredo Toledo-Leyva, Julio César Villegas-Pineda, Sergio Encarnación-Guevara, Dolores Gallardo-Rincón, Patricia Talamás-Rohana
Background: Epithelial ovarian cancer is the second most lethal gynecological cancer worldwide. Ascites can be found in all clinical stages, however in advanced disease stages IIIC and IV it is more frequent and could be massive, associated with worse prognosis. Due to the above, it was our interest to understanding how the ascites of ovarian cancer patients induces the mechanisms by which the cells present in it acquire a more aggressive phenotype and to know new proteins associated to this process...
2018: Proteome Science
https://www.readbyqxmd.com/read/29453576/monitoring-the-integrity-of-the-blood-testis-barrier-btb-an-in-vivo-assay
#15
Haiqi Chen, Wing-Yee Lui, Dolores D Mruk, Xiang Xiao, Renshan Ge, Qingquan Lian, Will M Lee, Bruno Silvestrini, C Yan Cheng
The blood-testis barrier is a unique ultrastructure in the mammalian testis, located near the basement membrane of the seminiferous tubule that segregates the seminiferous epithelium into the basal and the adluminal (apical) compartment. Besides restricting paracellular and transcellular passage of biomolecules (e.g., paracrine factors, hormones), water, electrolytes, and other substances including toxicants and/or drugs to enter the adluminal compartment of the epithelium, the BTB is an important ultrastructure that supports spermatogenesis...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29453575/regulation-of-blood-testis-barrier-btb-dynamics-role-of-actin-and-microtubule-based-cytoskeletons
#16
Qing Wen, Elizabeth I Tang, Nan Li, Dolores D Mruk, Will M Lee, Bruno Silvestrini, C Yan Cheng
The blood-testis barrier (BTB) is an important ultrastructure in the testis that supports meiosis and postmeiotic spermatid development since a delay in the establishment of a functional Sertoli cell barrier during postnatal development in rats or mice by 17-20 day postpartum (dpp) would lead to a delay of the first wave of meiosis. Furthermore, irreversible disruption of the BTB by toxicants also induces infertility in rodents. Herein, we summarize recent findings that BTB dynamics (i.e., disassembly, reassembly, and stabilization) are supported by the concerted efforts of the actin- and microtubule (MT)-based cytoskeletons...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29453339/a-role-for-tau-in-learning-memory-and-synaptic-plasticity
#17
Fabrizio Biundo, Dolores Del Prete, Hong Zhang, Ottavio Arancio, Luciano D'Adamio
Tau plays a pivotal role in the pathogenesis of neurodegenerative disorders: mutations in the gene encoding for tau (MAPT) are linked to Fronto-temporal Dementia (FTD) and hyper-phosphorylated aggregates of tau forming neurofibrillary tangles (NFTs) that constitute a pathological hallmark of Alzheimer disease (AD) and FTD. Accordingly, tau is a favored therapeutic target for the treatment of these diseases. Given the criticality of tau to dementia's pathogenesis and therapy, it is important to understand the physiological function of tau in the central nervous system...
February 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29452268/high-prevalence-of-liver-fibrosis-among-european-adults-with-unknown-liver-disease-a-population-based-study
#18
Llorenç Caballería, Guillem Pera, Ingrid Arteaga, Lluís Rodríguez, Alba Alumà, Rosa Ma Morillas, Napoleón de la Ossa, Alba Díaz, Carmen Expósito, Dolores Miranda, Carmen Sánchez, Rosa Ma Prats, Marta Urquizu, Angels Salgado, Magda Alemany, Alba Martinez, Irfan Majeed, Núria Fabrellas, Isabel Graupera, Ramón Planas, Isabel Ojanguren, Miquel Serra, Pere Torán, Juan Caballería, Pere Ginès
BACKGROUND AND AIMS: Liver fibrosis is the main determinant of long-term outcome in chronic liver diseases. Little is known about prevalence of liver fibrosis in general population. Aim of the study was to investigate the prevalence of liver fibrosis in general adult population with unknown liver disease. METHODS: Population-based, cross-sectional study, performed in Barcelona metropolitan area. Subjects aged 18-75yr were identified randomly from citizens included in primary health care registry...
February 13, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29452113/technological-innovation-strategies-for-the-specific-treatment-of-chagas-disease-based-on-benznidazole
#19
REVIEW
Leslie Raphael de Moura Ferraz, Alinne Élida Gonçalves Alves, Débora Dolores Souza da Silva Nascimento, Isabela Araújo E Amariz, Aline Silva Ferreira, Salvana Priscylla Manso Costa, Larissa Araújo Rolim, Ádley Antonini Neves de Lima, Pedro José Rolim Neto
Caused by Trypanosoma cruzi, Chagas disease is responsible for public health problems greater in magnitude than those attributed to malaria, schistosomiasis, or leishmaniasis. A factor in the socioeconomic development of poor countries, Chagas disease can cause death due to a high parasitic burden during its acute phase due and irreversible damage in organs such as the heart, esophagus, and colon during its chronic phase, even when the number of parasites is minimal. For treating Chagas disease, benznidazole (BNZ) remains the drug of choice and, in Latin America, the only drug on the market for treating the disease...
February 13, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29451100/ethnographic-analysis-of-communication-and-the-deaf-community-s-rights-in-the-clinical-context
#20
Dolors Rodríguez-Martín, Catalina Rodríguez-García, Anna Marta Falcó-Pegueroles
ABSTRAT Blackground: Communication is a key factor in people's interaction with the health system. In the case of Deaf Community -deaf sign language users- healthcare interactions could be affected by communication in a society that is mainly hearing and consequently, it can also have a negative impact on health and jeopardise some of their health rights. OBJECTIVES: . The aims were (i) to know the communication access difficulties of deaf people in healthcare context and (ii) determine how these difficulties violate their rights...
February 16, 2018: Contemporary Nurse
keyword
keyword
4555
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"