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https://www.readbyqxmd.com/read/29038041/minilaparoscopy-vs-standard-laparoscopy-for-sentinel-node-dissection-a-pilot-study
#1
Stefano Uccella, Alessandro Buda, Chiara Morosi, Giampaolo Di Martino, Martina Delle Marchette, Claudio Reato, Jvan Casarin, Fabio Ghezzi
OBJECTIVE: To compare 3-mm minilaparoscopy and standard 5-mm laparoscopy for sentinel node (SLN) detection in apparent early stage endometrial cancer (EC). DESIGN: Retrospective study (Canadian Task Force II-2). SETTING: Two academic research centers. PATIENTS: Consecutive women with apparent early stage EC, who underwent surgical staging with SLN between November 2015 and April 2016. INTERVENTIONS: Total laparoscopic extrafascial hysterectomy + bilateral salpingo-oophorectomy and SLN attempt...
October 13, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28832945/occurrence-of-osteon-banding-in-adult-human-cortical-bone
#2
Janna M Andronowski, Isaac V Pratt, David M L Cooper
OBJECTIVES: Differentiating human from nonhuman fragmented bone is often accomplished using histological methods if the observation of gross morphology proves insufficient. Linearly oriented primary and/or secondary osteonal systems, commonly referred to as osteon bands, are described as a strong indicator of nonhuman bone, particularly the occurrence of multiple bands. This phenomenon has been conventionally documented using two-dimensional (2D) histology, but such analyses are destructive and typically limited to a single cross-section...
August 19, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28748078/determination-of-the-protein-quality-of-cooked-canadian-pulses
#3
Matthew G Nosworthy, Jason Neufeld, Peter Frohlich, Gina Young, Linda Malcolmson, James D House
A study to determine the protein digestibility-corrected amino acid score and protein efficiency ratio of nine different cooked Canadian pulse classes was conducted in support of the establishment of protein quality claims in Canada and the United States. Split green and yellow pea, whole green lentil, split red lentil, Kabuli chickpea, navy bean, pinto bean, light red kidney bean, and black bean were investigated. Protein digestibility-corrected amino acid score (PDCAAS) and the protein efficiency ratio (PER) were determined using the appropriate rodent models...
July 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28531138/phytochemical-composition-and-antioxidant-capacity-of-seven-saskatoon-berry-amelanchier-alnifolia-nutt-genotypes-grown-in-poland
#4
Sabina Lachowicz, Jan Oszmiański, Łukasz Seliga, Stanisław Pluta
The basic chemical composition, bioactive compounds, and antioxidant capacity of fruits of three new Polish breeding clones (No. 5/6, type S, and type N) and four Canadian cultivars (cvs.) ("Martin", "Smoky", "Pembina", and "Honeywood") grown in Poland in 2016 were investigated. Fruits were analyzed for their contents of triterpenoids, carotenoids, chlorophylls, and polyphenolics with the ultra-performance liquid chromatography photodiode detector-quadrupole/time-of-flight mass spectrometry (UPLC-PDA-Q/TOF-MS) method, sugar with the high-performance liquid chromatography-evaporative light scattering detector (HPLC-ELSD) method, and antioxidant capacity with the ability to reduce free radical (ABTS) and ferric reducing ability of plasma (FRAP) method...
May 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28490927/how-different-is-cancer-control-across-canada-comparing-performance-indicators-for-prevention-screening-diagnosis-and-treatment
#5
R Rahal, J Chadder, K DeCaria, G Lockwood, H Bryant
Meaningful performance measures are an important part of the toolkit for health system improvement. The Canadian Partnership Against Cancer has been reporting on pan-Canadian cancer system performance indicators since 2009-work that has led to the availability of standardized measures that can help to shed light on the extent of variation and opportunities for quality improvement across the country. Those measures include a core set of system indicators ranging from prevention and screening, through diagnosis and treatment, to survivorship and end-of-life care...
April 2017: Current Oncology
https://www.readbyqxmd.com/read/28452761/respiratory-gated-kes-imaging-of-a-rat-model-of-acute-lung-injury-at-the-canadian-light-source
#6
P Deman, S Tan, G Belev, N Samadi, M Martinson, D Chapman, N L Ford
In this study, contrast-enhanced X-ray tomographic imaging for monitoring and quantifying respiratory disease in preclinical rodent models is proposed. A K-edge imaging method has been developed at the Canadian Light Source to very accurately obtain measurements of the concentration of iodinated contrast agent in the pulmonary vasculature and inhaled xenon in the airspaces of rats. To compare the iodine and xenon concentration maps, a scout projection image was acquired to define the region of interest within the thorax for imaging and to ensure the same locations were imaged in each K-edge subtraction (KES) acquisition...
May 1, 2017: Journal of Synchrotron Radiation
https://www.readbyqxmd.com/read/28303615/rare-earth-elements-and-select-actinoids-in-the-canadian-house-dust-study
#7
P E Rasmussen, C Levesque, M Chénier, H D Gardner
Nationally representative baseline data are presented for rare earth elements (REE), thorium (Th) and uranium (U) in house dust sampled from 1025 urban homes, in units of concentrations (μg g(-1) ), loadings (μg m(-2) ), and loading rates (ng m(-2)  d(-1) ). Spearman rank correlations indicate that, in addition to outdoor sources, consumer products and building materials can influence indoor dust concentrations of REE, Th, and U. Correlations (P<.01) with numbers of occupants, dogs, and cats suggest soil track-in...
September 2017: Indoor Air
https://www.readbyqxmd.com/read/28187382/adsorption-of-natural-organic-matter-and-disinfection-byproduct-precursors-from-surface-water-onto-tio2-nanoparticles-ph-effects-isotherm-modelling-and-implications-for-using-tio2-for-drinking-water-treatment
#8
Stephanie L Gora, Susan A Andrews
Titanium dioxide is a photocatalyst that can remove organic contaminants of interest to the drinking water treatment industry, including natural organic matter (NOM) and disinfection byproduct (DBP) precursors. The photocatalytic reaction occurs in two steps: adsorption of the contaminant followed by degradation of the adsorbed contaminant upon irradiation with UV light. The second part of this process can lead to the formation of reactive intermediates and negative impacts on treated water quality, such as increased DBP formation potential (DBPfp)...
May 2017: Chemosphere
https://www.readbyqxmd.com/read/28040926/a-sparsity-based-iterative-algorithm-for-reconstruction-of-micro-ct-images-from-highly-undersampled-projection-datasets-obtained-with-a-synchrotron-x-ray-source
#9
S Ali Melli, Khan A Wahid, Paul Babyn, David M L Cooper, Varun P Gopi
Synchrotron X-ray Micro Computed Tomography (Micro-CT) is an imaging technique which is increasingly used for non-invasive in vivo preclinical imaging. However, it often requires a large number of projections from many different angles to reconstruct high-quality images leading to significantly high radiation doses and long scan times. To utilize this imaging technique further for in vivo imaging, we need to design reconstruction algorithms that reduce the radiation dose and scan time without reduction of reconstructed image quality...
December 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28009575/medium-energy-microprobe-station-at-the-sxrmb-of-the-cls
#10
Qunfeng Xiao, Aimee Maclennan, Yongfeng Hu, Mark Hackett, Peter Leinweber, Tsun Kong Sham
Micro-XAFS and chemical imaging techniques have been widely applied for studies of heterogeneously distributed systems, mostly in hard X-ray (>5 keV) or in soft X-ray (<1.5 keV) energies. The microprobe endstation of the SXRMB (soft X-ray microcharacterization beamline) at the Canadian Light Source is optimized at the medium energy (1.7-5 keV), and it has been recently commissioned and is available for general users. The technical design and the performance (energy range, beam size and flux) of the SXRMB microprobe are presented...
January 1, 2017: Journal of Synchrotron Radiation
https://www.readbyqxmd.com/read/28002578/linking-the-canadian-community-health-survey-and-the-canadian-mortality-database-an-enhanced-data-source-for-the-study-of-mortality
#11
Claudia Sanmartin, Yves Decady, Richard Trudeau, Abel Dasylva, Michael Tjepkema, Philippe Finès, Rick Burnett, Nancy Ross, Douglas G Manuel
BACKGROUND: This study summarizes the linkage of the Canadian Community Health Survey (CCHS) and the Canadian Mortality Database (CMDB), which was performed to examine relationships between social determinants, health behaviours and mortality in the household population. DATA AND METHODS: The 2000/2001-to-2011 Canadian Community Health Surveys were linked to the 2000-to-2011 CMDB using probabilistic methods based on common identifiers (names, date of birth, postal code and sex) for eligible respondents (85%; n = 614,774)...
December 21, 2016: Health Reports
https://www.readbyqxmd.com/read/27804925/multiple-energy-synchrotron-biomedical-imaging-system
#12
B Bassey, M Martinson, N Samadi, G Belev, C Karanfil, P Qi, D Chapman
A multiple energy imaging system that can extract multiple endogenous or induced contrast materials as well as water and bone images would be ideal for imaging of biological subjects. The continuous spectrum available from synchrotron light facilities provides a nearly perfect source for multiple energy x-ray imaging. A novel multiple energy x-ray imaging system, which prepares a horizontally focused polychromatic x-ray beam, has been developed at the BioMedical Imaging and Therapy bend magnet beamline at the Canadian Light Source...
November 2, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27787256/measuring-the-criticality-of-the-magic-condition-for-a-beam-expanding-monochromator
#13
Mercedes Martinson, Dean Chapman
It has been established that for cylindrically bent crystals the optimal beam characteristics occur when the geometric and single-ray foci are matched. In the beam-expanding monochromator developed for the BioMedical Imaging and Therapy beamlines at the Canadian Light Source, it was unclear how critical this `magic condition' was for preserving the transverse coherence of the beam. A study was conducted to determine whether misalignments away from the ideal conditions would severely affect the transverse coherence of the beam, thereby limiting phase-based imaging techniques...
November 1, 2016: Journal of Synchrotron Radiation
https://www.readbyqxmd.com/read/27687902/do-baby-boomers-use-more-healthcare-services-than-other-generations-longitudinal-trajectories-of-physician-service-use-across-five-birth-cohorts
#14
Mayilee Canizares, Monique Gignac, Sheilah Hogg-Johnson, Richard H Glazier, Elizabeth M Badley
OBJECTIVE: In light of concerns for meeting the provision of healthcare services given the large numbers of ageing baby boomers, we compared the trajectories of primary care and specialist services use across the lifecourse of 5 birth cohorts and examined factors associated with birth cohort differences. DESIGN: Longitudinal panel. SETTING: Canadian National Population Health Survey (1994-2011). POPULATION: Sample of 10 186 individuals aged 20-69 years in 1994-1995 and who were from 5 birth cohorts: Generation X (Gen X; born: 1965-1974), Younger Baby Boomers (born: 1955-1964), Older Baby Boomers (born: 1945-1954), World War II (born: 1935-1944) and pre-World War II (born: 1925-1934)...
2016: BMJ Open
https://www.readbyqxmd.com/read/27453203/bmit-facility-at-the-canadian-light-source-advances-in-x-ray-phase-sensitive-imaging
#15
T W Wysokinski, J P Ianowski, X Luan, G Belev, D Miller, M A Webb, N Zhu, D Chapman
The BioMedical Imaging and Therapy (BMIT) facility [1,2] located at the Canadian Light Source, provides synchrotron-specific imaging and radiation therapy capabilities. There are two separate beamlines used for experiments: the bending magnet (05B1-1) and the insertion device (05ID-2) beamline. The bending magnet beamline provides access to monochromatic beam spanning a spectral range of 15-40keV, and the beam is 240mm wide in the POE-2 experimental hutch. Users can also perform experiments with polychromatic (pink) beam...
December 2016: Physica Medica: PM
https://www.readbyqxmd.com/read/27320962/three-dimensional-labeling-of-newly-formed-bone-using-synchrotron-radiation-barium-k-edge-subtraction-imaging
#16
Arash Panahifar, Treena M Swanston, M Jake Pushie, George Belev, Dean Chapman, Lynn Weber, David M L Cooper
Bone is a dynamic tissue which exhibits complex patterns of growth as well as continuous internal turnover (i.e. remodeling). Tracking such changes can be challenging and thus a high resolution imaging-based tracer would provide a powerful new perspective on bone tissue dynamics. This is, particularly so if such a tracer can be detected in 3D. Previously, strontium has been demonstrated to be an effective tracer which can be detected by synchrotron-based dual energy K-edge subtraction (KES) imaging in either 2D or 3D...
June 20, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27303896/putative-thioredoxin-trx1-from-thermosipho-africanus-strain-tcf52b-expression-purification-and-structural-determination-using-s-sad
#17
Naheda Sahtout, Jijin R A Kuttiyatveetil, Michel Fodje, David A R Sanders
Thioredoxin is a small ubiquitous protein that plays a role in many biological processes. A putative thioredoxin, Trx1, from Thermosipho africanus strain TCF52B, which has low sequence identity to its closest homologues, was successfully cloned, overexpressed and purified. The protein was crystallized using the microbatch-under-oil technique at 289 K in a variety of conditions; crystals grown in 0.2 M MgCl2, 0.1 M bis-tris pH 6.5, 25%(w/v) PEG 3350, which grew as irregular trapezoids to maximum dimensions of 1...
June 2016: Acta Crystallographica. Section F, Structural Biology Communications
https://www.readbyqxmd.com/read/27140158/synchrotron-radiation-based-x-ray-micro-computed-tomography-reveals-dental-bur-debris-under-dental-composite-restorations
#18
Assem Hedayat, Nicole Nagy, Garnet Packota, Judy Monteith, Darcy Allen, Tomasz Wysokinski, Ning Zhu
Dental burs are used extensively in dentistry to mechanically prepare tooth structures for restorations (fillings), yet little has been reported on the bur debris left behind in the teeth, and whether it poses potential health risks to patients. Here it is aimed to image dental bur debris under dental fillings, and allude to the potential health hazards that can be caused by this debris when left in direct contact with the biological surroundings, specifically when the debris is made of a non-biocompatible material...
May 2016: Journal of Synchrotron Radiation
https://www.readbyqxmd.com/read/27014719/demonstration-of-synchrotron-x-ray-phase-contrast-imaging-computed-tomography-of-infiltrative-transitional-cell-carcinoma-of-the-prostatic-urethra-in-a-dog
#19
James E Montgomery, Michal J Wesolowski, Bailey Wolkowski, Rajni Chibbar, Elisabeth C R Snead, Jaswant Singh, Murray Pettitt, Pritpal S Malhi, Trinita Barboza, Gregg Adams
Prostatic urethral transitional cell carcinoma with prostatic invasion in a dog was imaged with abdominal radiography and abdominal ultrasonography antemortem. Synchrotron in-line x-ray phase contrast imaging computed tomography (XPCI-CT) was performed on the prostate ex vivo at the Canadian Light Source Synchrotron and compared to histology. XPCI-CT imaging provides greater soft tissue contrast than conventional absorption-based x-ray imaging modalities, permitting visualization of regions of inflammatory cell infiltration, differentiation of invasive versus noninvasive tumor regions, and areas of necrosis and mineralization...
January 2016: Journal of Medical Imaging
https://www.readbyqxmd.com/read/26289283/design-of-a-mouse-restraint-for-synchrotron-based-computed-tomography-imaging
#20
Kenneth B Gagnon, Sally Caine, Nazanin Samadi, Mercedes Martinson, Melanie van der Loop, Jane Alcorn, L Dean Chapman, George Belev, Helen Nichol
High-resolution computed tomography (CT) imaging of a live animal within a lead-lined synchrotron light hutch presents several unique challenges. In order to confirm that the animal is under a stable plane of anaesthesia, several physiological parameters (e.g. heart rate, arterial oxygen saturation, core body temperature and respiratory rate) must be remotely monitored from outside the imaging hutch. In addition, to properly scan the thoracic region using CT, the animal needs to be held in a vertical position perpendicular to the fixed angle of the X-ray beam and free to rotate 180°-360°...
September 2015: Journal of Synchrotron Radiation
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