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https://www.readbyqxmd.com/read/28919803/empirical-validation-of-the-horowitz-multiple-systemic-infectious-disease-syndrome-questionnaire-for-suspected-lyme-disease
#1
Maryalice Citera, Phyllis R Freeman, Richard I Horowitz
PURPOSE: Lyme disease is spreading worldwide, with multiple Borrelia species causing a broad range of clinical symptoms that mimic other illnesses. A validated Lyme disease screening questionnaire would be clinically useful for both providers and patients. Three studies evaluated such a screening tool, namely the Horowitz Multiple Systemic Infectious Disease Syndrome (MSIDS) Questionnaire. The purpose was to see if the questionnaire could accurately distinguish between Lyme patients and healthy individuals...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28912726/cardiovascular-and-muscular-consequences-of-work-matched-interval-type-of-concentric-and-eccentric-pedaling-exercise-on-a-soft-robot
#2
Martin Flück, Rebekka Bosshard, Max Lungarella
Eccentric types of endurance exercise are an acknowledged alternative to conventional concentric types of exercise rehabilitation for the cardiac patient, because they reduce cardiorespiratory strain due to a lower metabolic cost of producing an equivalent mechanical output. The former contention has not been tested in a power- and work-matched situation of interval-type exercise under identical conditions because concentric and eccentric types of exercise pose specific demands on the exercise machinery, which are not fulfilled in current practice...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28911611/antifatigue-and-increasing-exercise-performance-of-actinidia-arguta-crude-alkaloids-in-mice
#3
Yangyang Liu, Changjiang Liu
Actinidia arguta (Siebold et Zucc.) Planch. ex. Miq. is one of the most recently domesticated fruit species with increasing commercial production worldwide. It is a well-known traditional Chinese medicine and is used to reduce blood glucose and treat atopic dermatitis. In addition, it possesses antioxidant, anticancer, and antiallergic properties. In this study, we investigated the physical antifatigue and exercise performance effects of A. arguta crude alkaloids (AACA) extracted with 70% ethanol. Four groups of male Kunming mice (n = 16) were orally administered AACA at doses of 0 mg/kg/d (vehicle), 50 mg/kg/d (AACA-50), 100 mg/kg/d (AACA-100), or 200 mg/kg/d (AACA-200) for 28 days...
October 2016: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28890898/antifatigue-functions-and-mechanisms-of-edible-and-medicinal-mushrooms
#4
REVIEW
Ping Geng, Ka-Chai Siu, Zhaomei Wang, Jian-Yong Wu
Fatigue is the symptom of tiredness caused by physical and/or psychological stresses. As fatigue is becoming a serious problem in the modern society affecting human health, work efficiency, and quality of life, effective antifatigue remedies other than pharmacological drugs or therapies are highly needed. Mushrooms have been widely used as health foods, because of their various bioactive constituents such as polysaccharides, proteins, vitamins, minerals, and dietary fiber. This paper reviews the major findings from previous studies on the antifatigue effects, the active components of mushrooms, and the possible mechanisms...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28889846/acupuncture-for-management-of-type-2-diabetes-mellitus-in-a-patient-with-myasthenia-gravis-a-case-report
#5
Yun Jin Kim
Myasthenia gravis (MG) is an acquired disease of the neuromuscular junctions characterized by muscular weakness and fatigue, with a prevalence of 50-125 cases per million population in western countries. In men, it usually appears after the age of 60 years, while in women, it usually appears before the age of 40 years. Long-term immunosuppression with corticosteroids is the mainstay treatment for patients with MG; however, the use of corticosteroids is a well-documented risk factor for type 2 diabetes mellitus, which has also been reported in steroid-treated patients with MG...
August 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28878457/effects-of-chronic-ankle-instability-and-induced-mediolateral-muscular-fatigue-of-the-ankle-on-competitive-taekwondo-athletes
#6
Myeounggon Lee, Changhong Youm, Minji Son, Jinhee Kim, Youkyung Kim
[Purpose] The purpose of this study was to investigate the effects of chronic ankle instability and induced mediolateral muscular fatigue of the ankle on competitive Taekwondo athletes during single-leg drop landing. [Subjects and Methods] Fourteen competitive taekwondo athletes with chronic ankle instability and 14 healthy adults participated, and they performed three single-leg drop landings from a 40-cm height before and after induced fatigue. Ankle angular position, peak vertical ground reaction force, loading rate, eccentric work, and contribution were calculated and analyzed...
August 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28827517/rhabdomyolysis-in-a-patient-with-severe-hypothyroidism
#7
Nooshin Salehi, Endre Agoston, Iqbal Munir, Gary J Thompson
BACKGROUND Muscular symptoms, including stiffness, myalgia, cramps, and fatigue, are present in the majority of the patients with symptomatic hypothyroidism, but rhabdomyolysis, the rapid breakdown of skeletal muscle, is a rare manifestation. In most patients with hypothyroidism who develop rhabdomyolysis, precipitating factors, such as strenuous exercise or use of lipid-lowering drugs, can be identified. CASE REPORT We report a case of a 52-year-old Hispanic woman with a history of hypothyroidism, hypertension, and type 2 diabetes mellitus who presented with fatigue, severe generalized weakness, bilateral leg pain, and recurrent falls...
August 22, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28820647/acute-fatigue-negatively-affects-risk-factors-for-injury-in-trained-but-not-well-trained-habitually-shod-runners-when-running-barefoot
#8
Nicholas Tam, Devon R Coetzee, Safwaan Ahmed, Robert P Lamberts, Yumna Albertus-Kajee, Ross Tucker
INTRODUCTION: Many factors may contribute to running-related injury. These include fatigue and footwear, the combination of which has rarely been studied, in particular with reference to barefoot running, recently advocated as a method to reduce injury risk. METHODS: Twenty-two runners (12 well-trained and 10 trained) participated in a 10 km fatiguing trial. Knee and ankle joint kinematics and kinetics and electromyography were assessed during overground running in the barefoot and shod condition...
August 18, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28813798/a-novel-method-for-muscle-fatigue-assessment-during-robot-based-tracking-tasks
#9
Maddalena Mugnosso, Francesca Marini, Matteo Gillardo, Pietro Morasso, Jacopo Zenzeri
In this work we propose a novel method based on sEMG signals, easy and fast to perform, administered with a robotic device to maximize repeatability and objectivity. Muscle fatigue, which is frequently experienced by healthy subjects, can be a highly debilitating symptom in case of neuromuscular disorders. Its assessment provides crucial information on the progression of the disability itself, on patient's muscular function and on the efficacy of the eventual clinical intervention. Hence, a robust and objective protocol for fatigue assessment is fundamental in rehabilitation practice...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28803817/6mwt-can-identify-type-3-sma-patients-with-neuromuscular-junction-dysfunction
#10
REVIEW
Maria Carmela Pera, Marco Luigetti, Marika Pane, Giorgia Coratti, Nicola Forcina, Lavinia Fanelli, Elena S Mazzone, Laura Antonaci, Leonardo Lapenta, Concetta Palermo, Domiziana Ranalli, Giuseppe Granata, Mauro Lomonaco, Serenella Servidei, Eugenio Mercuri
The aim of the study was to establish if the decrease in gait velocity on the 6 minute walk test relates to signs of neuromuscular junction dysfunction in spinal muscular atrophy type 3 patients. 6 minute walk test and low-rate repetitive nerve stimulation test were performed in fifteen ambulant patients with spinal muscular atrophy type 3 of age between 9 and 66 years. The 6 minute walk distance ranged between 66 and 575 m. The difference between the first and the 6th minute ranged between 0 and -69%. The low-rate repetitive nerve stimulation test measured in % of loss ranged between -31...
July 14, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28797855/exploring-genetic-attributions-underlying-radiotherapy-induced-fatigue-in-prostate-cancer-patients
#11
Sepehr Hashemi, Juan Luis Fernandez Martinez, Leorey Saligan, Stephen Sonis
CONTEXT: Despite numerous proposed mechanisms, no definitive pathophysiology underlying Radiotherapy-Induced Fatigue (RIF) has been established. However, the dysregulation of a set of 35 genes was recently validated to predict development of fatigue in prostate cancer patients (PCP's) receiving radiotherapy. OBJECTIVES: To hypothesize novel pathways, and provide genetic targets for currently proposed pathways implicated in RIF development through analysis of the previously validated gene set...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28797049/effect-of-sodium-bicarbonate-on-prolonged-running-performance-a-randomized-double-blind-cross-over-study
#12
Tanja Freis, Anne Hecksteden, Ulf Such, Tim Meyer
BACKGROUND: The ability to sustain intense exercise seems to be partially limited by the body's capability to counteract decreases in both intra- and extracellular pH. While the influence of an enhanced buffering capacity via sodium bicarbonate (BICA) on short-term, high-intensity exercise performance has been repeatedly investigated, studies on prolonged endurance performances are comparatively rare, especially for running. The aim of the following study was to assess the ergogenic effects of an oral BICA substitution upon exhaustive intensive endurance running performance...
2017: PloS One
https://www.readbyqxmd.com/read/28795383/integrated-imaginative-distention-therapy-to-cope-with-fatigue-dimmi-si-study-the-first-randomized-controlled-trial-in-multiple-sclerosis
#13
Annalisa Sgoifo, Angelo Bignamini, Loredana La Mantia, Maria G Celani, Piero Parietti, Maria A Ceriani, Maria R Marazzi, Paola Proserpio, Lino Nobili, Alessandra Protti, Elio C Agostoni
INTRODUCTION: Fatigue is a frequent, disabling, and difficult to treat symptom in neurological disease and in other stress-related conditions; Integrated Imaginative Distention (IID) is a therapy combining muscular and imaginative relaxation, feasible also in disabled subjects; the DIMMI SI trial was planned to evaluate IID efficacy on fatigue. METHODS: The design was a parallel, randomised 1:1 (intervention:waiting list), controlled, open-label trial. Participants were persons with multiple sclerosis (pwMS), persons with insomnia (pwINS), and health professionals (HP) as conditions related to fatigue and stress...
August 9, 2017: Neurology and Therapy
https://www.readbyqxmd.com/read/28793865/perceived-consequences-of-ageing-with-late-effects-of-polio-and-strategies-for-managing-daily-life-a-qualitative-study
#14
Catharina Sjödahl Hammarlund, Jan Lexell, Christina Brogårdh
BACKGROUND: New or increased impairments may develop several decades after an acute poliomyelitis infection. These new symptoms, commonly referred to as late effects of polio (LEoP), are characterised by muscular weakness and fatigue, generalised fatigue, pain at rest or during activities and cold intolerance. Growing older with LEoP may lead to increased activity limitations and participation restrictions, but there is limited knowledge of how these persons perceive the practical and psychological consequences of ageing with LEoP and what strategies they use in daily life...
August 9, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28763003/short-term-effects-of-a-ready-to-drink-pre-workout-beverage-on-exercise-performance-and-recovery
#15
Patrick B Collins, Conrad P Earnest, Ryan L Dalton, Ryan J Sowinski, Tyler J Grubic, Christopher J Favot, Adriana M Coletta, Christopher Rasmussen, Mike Greenwood, Richard B Kreider
In a double-blind, randomized and crossover manner, 25 resistance-trained participants ingested a placebo (PLA) beverage containing 12 g of dextrose and a beverage (RTD) containing caffeine (200 mg), β-alanine (2.1 g), arginine nitrate (1.3 g), niacin (65 mg), folic acid (325 mcg), and Vitamin B12 (45 mcg) for 7-days, separated by a 7-10-day. On day 1 and 6, participants donated a fasting blood sample and completed a side-effects questionnaire (SEQ), hemodynamic challenge test, 1-RM and muscular endurance tests (3 × 10 repetitions at 70% of 1-RM with the last set to failure on the bench press (BP) and leg press (LP)) followed by ingesting the assigned beverage...
August 1, 2017: Nutrients
https://www.readbyqxmd.com/read/28753624/muscular-fatigue-in-response-to-different-modalities-of-crossfit-sessions
#16
José Luis Maté-Muñoz, Juan H Lougedo, Manuel Barba, Pablo García-Fernández, Manuel V Garnacho-Castaño, Raúl Domínguez
BACKGROUND: CrossFit is a new strength and conditioning regimen involving short intense daily workouts called workouts of the day (WOD). This study assesses muscular fatigue levels induced by the three modalities of CrossFit WOD; gymnastics (G), metabolic conditioning (M) and weightlifting (W). MATERIAL AND METHODS: 34 healthy subjects undertook three WOD (one per week): a G WOD consisting of completing the highest number of sets of 5 pull-ups, 10 push-ups and 15 air squats in 20 min; an M WOD, in which the maximum number of double skipping rope jumps was executed in 8 sets (20 s), resting (10 s) between sets; and finally, a W WOD in which the maximum number of power cleans was executed in 5 min, lifting a load equivalent to 40% of the individual's 1RM...
2017: PloS One
https://www.readbyqxmd.com/read/28752919/acute-physiological-and-perceptual-responses-to-high-load-resistance-exercise-in-hypoxia
#17
Brendan R Scott, Katie M Slattery, Dean V Sculley, Scott M Smith, Jeremiah J Peiffer, Ben J Dascombe
This study assessed whether hypoxia during high-load resistance exercise could enhance the acute physiological responses related to muscular development. Twelve trained men performed exercise in three conditions: normoxia (fraction of inspired oxygen [FI O2 ] = 21%), moderate-level hypoxia (FI O2  = 16%) and high-level hypoxia (FI O2  = 13%). Exercise comprised high-load squats and deadlifts (5 × 5 using 80% of 1-repetition maximum with 180-s rest). Muscle oxygenation and activation were monitored during exercise...
July 28, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28746422/patients-with-duchenne-and-becker-muscular-dystrophies-are-not-more-asymmetrical-than-healthy-controls-on-timed-performance-of-upper-limb-tasks
#18
M C Artilheiro, C S C Sá, F M Fávero, F A Caromano, M C Voos
This study aimed to investigate possible asymmetries and relationships between performance of dominant and non-dominant upper limbs (UL) in patients with Duchenne and Becker muscular dystrophies (DMD/BMD), to compare UL performance of patients and healthy subjects and to investigate the relationship between timed performance of UL and age, motor function and muscle strength in DMD/BMD patients. Sixteen patients with DMD and 3 with BMD were evaluated with Jebsen-Taylor Test (timed performance), Vignos scale and Dimension 3 of Motor Function Measure (motor function), and Medical Research Council scale (muscle strength) on a single session...
July 24, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28704311/acute-neuromuscular-and-endocrine-responses-to-two-different-compound-exercises-squat-versus-deadlift
#19
Matthew J Barnes, Adam Miller, Daniel Reeve, Robin Jc Stewart
Anecdotally, it is believed that the deadlift exercise brings about greater levels of central fatigue than other exercises; however no empirical evidence exists to support this view. Additionally, little is known about the acute endocrine response to heavy deadlift exercise and how this may differ to other similar compound exercises. Therefore, the aim of this study was to identify and compare the acute, neuromuscular and endocrine responses to squat and deadlift exercise. Ten resistance trained males completed 8 sets of 2 repetitions at 95 % of one repetition maximum...
July 12, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28701169/comparison-between-semg-and-force-as-control-interfaces-to-support-planar-arm-movements-in-adults-with-duchenne-a-feasibility-study
#20
Joan Lobo-Prat, Kostas Nizamis, Mariska M H P Janssen, Arvid Q L Keemink, Peter H Veltink, Bart F J M Koopman, Arno H A Stienen
BACKGROUND: Adults with Duchenne muscular dystrophy (DMD) can benefit from devices that actively support their arm function. A critical component of such devices is the control interface as it is responsible for the human-machine interaction. Our previous work indicated that surface electromyography (sEMG) and force-based control with active gravity and joint-stiffness compensation were feasible solutions for the support of elbow movements (one degree of freedom). In this paper, we extend the evaluation of sEMG- and force-based control interfaces to simultaneous and proportional control of planar arm movements (two degrees of freedom)...
July 12, 2017: Journal of Neuroengineering and Rehabilitation
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