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https://www.readbyqxmd.com/read/29786953/iatrogenic-botulism-outbreak-in-egypt-due-to-a-counterfeit-botulinum-toxin-a-preparation-a-descriptive-series-of-patient-features-and-outcome
#1
Eman Abdel Monaem Abdel Rashid, Nashwa Mohamed El-Mahdy, Huda Shehata Kharoub, Ahmed Salah Gouda, Naglaa Ahmed ElNabarawy, Bruno Mégarbane
Iatrogenic botulism resulting from the substantial increase in use of botulinum neurotoxin type-A (BoNT-A) treatment is rarely reported. We aimed to describe a large iatrogenic botulism outbreak in Egypt in June-July 2017. Nine patients developed botulism after receiving intramuscular injections of BoNT-A (dose: 200-300 IU) to treat cerebral palsy (N=7), spastic dystonia (N=1), and hyperhidrosis (N=1). Detailed findings were available in 5/9 cases. Patients were admitted to the hospital 5-10 days after the BoNT-A injection...
May 22, 2018: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29775865/influence-of-fatigue-and-velocity-on-the-latency-and-recruitment-order-of-scapular-muscles
#2
Guillermo Mendez-Rebolledo, Valeska Gatica-Rojas, Eduardo Guzman-Muñoz, Eduardo Martinez-Valdes, Rodrigo Guzman-Venegas, Francisco Jose Berral de la Rosa
OBJECTIVES: To determine the influence of velocity and fatigue on scapular muscle activation latency and recruitment order during a voluntary arm raise task, in healthy individuals. DESIGN: Cross-sectional study. SETTING: University laboratory. PARTICIPANTS: Twenty three male adults per group (high-velocity and low-velocity). MAIN OUTCOME MEASURES: Onset latency of scapular muscles [Anterior deltoid (AD), lower trapezius (LT), middle trapezius (MT), upper trapezius (UT), and serratus anterior (SA)] was assessed by surface electromyography...
April 19, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29775379/decision-to-return-to-sport-participation-after-anterior-cruciate-ligament-reconstruction-part-ii-self-reported-and-functional-performance-outcomes
#3
Jennifer L Werner, Julie P Burland, Carl G Mattacola, Jenny Toonstra, Robert A English, Jennifer S Howard
CONTEXT:   Anterior cruciate ligament (ACL) reconstruction (ACLR) is the most commonly used method for helping athletes regain function and return to preinjury activity levels after ACL injury. Outcomes after ACLR have suggested that athletes return to a level of function that would support a return to sport participation; however, in a recent meta-analysis, pooled return rates were only 55%. It is unclear whether this discrepancy is a result of functional impairments. OBJECTIVE:   To compare patient-reported outcomes (PROs), dynamic balance, dynamic functional performance, strength, and muscular endurance in athletes who have returned to sport (RTS) and athletes who have not returned to sport (NRTS) after ACLR...
May 18, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29770505/poor-self-reported-sleep-quality-and-health-related-quality-of-life-in-patients-with-chronic-fatigue-syndrome-myalgic-encephalomyelitis
#4
Jesús Castro-Marrero, Maria C Zaragozá, Sergio González-Garcia, Luisa Aliste, Naia Sáez-Francàs, Odile Romero, Alex Ferré, Tomás Fernández de Sevilla, José Alegre
Non-restorative sleep is a hallmark symptom of chronic fatigue syndrome/myalgic encephalomyelitis. However, little is known about self-reported sleep disturbances in these subjects. This study aimed to assess the self-reported sleep quality and its impact on quality of life in a Spanish community-based chronic fatigue syndrome/myalgic encephalomyelitis cohort. A prospective cross-sectional cohort study was conducted in 1,455 Spanish chronic fatigue syndrome/myalgic encephalomyelitis patients. Sleep quality, fatigue, pain, functional capacity impairment, psychopathological status, anxiety/depression and health-related quality of life were assessed using validated subjective measures...
May 16, 2018: Journal of Sleep Research
https://www.readbyqxmd.com/read/29761311/comparison-of-fatigue-responses-and-rapid-force-characteristics-between-explosive-and-traditional-resistance-trained-males
#5
Cameron S Mackey, Ryan M Thiele, Eric C Conchola, Jason M DeFreitas
PURPOSE: To compare maximal and rapid force characteristics, as well as fatigability, between traditional (TRT) and explosive (ERT) resistance-trained men. METHODS: Fourteen TRT (mean age = 25 years) and twelve ERT (mean age = 22 years) men performed rapid maximal contractions followed by an isokinetic fatigue protocol consisting of 50 maximal knee extension (KE) and flexions (KF) at a moderate speed (180° s- ¹). Baseline measures included: isokinetic peak torque (PT), isometric rate of torque development (RTD0-50 ), peak acceleration (ACCmax ), and peak velocity (Vmax )...
May 14, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29758055/active-recovery-affects-the-recovery-of-the-corticospinal-system-but-not-of-muscle-contractile-properties
#6
Louis-Solal Giboin, Ehsan Amiri, Raphael Bertschinger, Markus Gruber
PURPOSE: Active recovery is often used by athletes after strenuous exercise or competition but its underlying mechanisms are not well understood. We hypothesized that active recovery speeds-up recovery processes within the muscle and the central nervous system (CNS). METHODS: We assessed muscular and CNS recovery by measuring the voluntary activation (VA) in the vastus lateralis muscle with transcranial magnetic stimulation (VATMS) and peripheral nerve stimulation (VAPNS) during maximal voluntary contractions (MVC) of the knee extensors in 11 subjects...
2018: PloS One
https://www.readbyqxmd.com/read/29748158/scoping-review-of-dance-for-adults-with-fibromyalgia-what-do-we-know-about-it
#7
REVIEW
Julia Bidonde, Catherine Boden, Soo Kim, Angela J Busch, Suelen M Goes, Emily Knight
BACKGROUND: Fibromyalgia is a chronic disorder characterized by widespread muscular tenderness, pain, fatigue, and cognitive difficulties. Nonpharmacological treatment options, such as physical activity, are important for people with fibromyalgia. There are strong recommendations to support engagement in physical activity for symptom management among adults with fibromyalgia. Dance is a mode of physical activity that may allow individuals with fibromyalgia to improve their physical function, health, and well-being...
May 10, 2018: JMIR Rehabilitation and Assistive Technologies
https://www.readbyqxmd.com/read/29744108/self-reported-fatigue-following-intensive-care-of-chronically-critically-ill-patients-a-prospective-cohort-study
#8
Gloria-Beatrice Wintermann, Jenny Rosendahl, Kerstin Weidner, Bernhard Strauß, Andreas Hinz, Katja Petrowski
Background: Protracted treatment on intensive care unit (ICU) sets the patients at increased risk for the development of chronic critical illness (CCI). Muscular and cardio-respiratory deconditioning are common long-term sequelae, going along with a state of chronic fatigue. At present, findings regarding the frequency, long-term course, and associated factors of self-reported fatigue following ICU treatment of CCI patients are lacking. Methods: CCI patients with the diagnosis of critical illness polyneuropathy/myopathy (CIP/CIM) were assessed at three time points...
2018: Journal of Intensive Care
https://www.readbyqxmd.com/read/29736344/movement-velocity-in-the-chair-squat-is-associated-with-measures-of-functional-capacity-and-cognition-in-elderly-people-at-low-risk-of-fall
#9
Carlos Balsalobre-Fernández, Ángel Cordón, Nazaret Unquiles, Daniel Muñoz-García
Background: The purpose of this study was to analyze the relationships between muscular performance consisting of a single repetition on the chair squat exercise (CSQ) and different measures of functional capacity, balance, quality of life and cognitive status in older adults. Methods: A total of 40 participants (22 women, 18 men; age = 72.2 ± 4.9 years) joined the investigation. Muscular performance was assessed by measuring movement velocity in the CSQ with no external load using a validated smartphone application ( PowerLift for iOS)...
2018: PeerJ
https://www.readbyqxmd.com/read/29722617/cheap-labor-myosin-fiber-type-expression-and-enzyme-activity-in-the-forelimb-musculature-of-sloths-pilosa-xenarthra
#10
Kyle B Spainhower, Rebecca N Cliffe, Allan K Metz, Ernest M Barkett, Paije M Kiraly, Dylan R Thomas, Sarah J Kennedy, Judy Avey-Arroyo, Michael T Butcher
Sloths are canopy-dwelling inhabitants of American neotropical rainforests that exhibit suspensory behaviors. These abilities require both strength and muscular endurance to hang for extended periods of time; however, the skeletal muscle mass of sloths is reduced, thus requiring modifications to muscle architecture and leverage for large joint torque. We hypothesize that intrinsic muscle properties also are modified for fatigue resistance and predict a heterogeneous expression of slow/fast myosin heavy chain (MHC) fibers that utilize oxidative metabolic pathways for economic force production...
May 3, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29720793/edgar-adrian-and-patrick-merton-names-blurred-with-the-passage-of-time
#11
Kalyan B Bhattacharyya
Edgar Douglas Adrian and Patrick Anthony Merton are two supreme neurophysiologists from England in the last century whose names are almost forgotten these days. Adrian's work on all-or-none phenomenon in nerve and muscle excitability ushered in a new era and Merton's servo theory of muscular movement and muscle fatigue added a new dimension to the understanding of stretch reflex and deep tendon reflexes. Both of them trained and worked at Trinity College, Cambridge and both were elected as Fellow of the Royal Society and Adrian in addition, was awarded the Nobel Prize in 1932 along with Charles Scott Sherrington...
January 2018: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/29719079/effects-of-ipsilateral-and-contralateral-fatigue-and-muscle-blood-flow-occlusion-on-the-complexity-of-knee-extensor-torque-output-in-humans
#12
Jamie Pethick, Samantha L Winter, Mark Burnley
NEW FINDINGS: In this study we show that the fatigue-induced loss of isometric torque complexity does not recover if the fatigued muscle's blood flow is occluded during recovery, suggesting a pivotal role for peripheral mechanisms in this effect. When the contralateral limb is fatigued, the complexity of isometric torque output is unaffected even if the contralateral limb's blood flow is occluded, which suggests neither central fatigue nor afferent feedback from ischaemic muscle influence the complexity of torque output in an otherwise fresh muscle...
May 2, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29705158/efficacy-of-combined-electrostimulation-in-patients-with-acute-exacerbation-of-copd-randomised-clinical-trial
#13
REVIEW
Laura Lopez Lopez, Maria Granados Santiago, Maria Donaire Galindo, Irene Torres Sanchez, Araceli Ortiz Rubio, Marie Carmen Valenza
INTRODUCTION AND OBJECTIVE: Muscle dysfunction is very common in patients with chronic obstructive pulmonary disease (COPD). Muscular strength depletion is a result of numerous hospitalisations and this causes an increase in the symptomatology. Numerous interventions have been used in these patients, but there is no consensus on the best. The main objective of this study is to compare the effectiveness of two physiotherapy interventions during hospitalisation in COPD patients. PATIENTS AND METHODS: In this clinical trial, we included 39 patients who were randomised into three groups...
April 25, 2018: Medicina Clínica
https://www.readbyqxmd.com/read/29687013/effects-of-game-pitch-count-and-body-mass-index-on-pitching-biomechanics-in-9-to-10-year-old-baseball-athletes
#14
Jim D Darke, Eshan M Dandekar, Arnel L Aguinaldo, Scott J Hazelwood, Stephen M Klisch
Background: Pitching while fatigued and body composition may increase the injury risk in youth and adult pitchers. However, the relationships between game pitch count, biomechanics, and body composition have not been reported for a study group restricted to 9- to 10-year-old athletes. Hypothesis: During a simulated game with 9- to 10-year-old athletes, (1) participants will experience biomechanical signs of fatigue, and (2) shoulder and elbow kinetics will correlate with body mass index (BMI)...
April 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29656018/systematic-analysis-of-the-cerebrospinal-fluid-proteome-of-fibromyalgia-patients
#15
Payam Emami Khoonsari, Sravani Musunri, Stephanie Herman, Camilla I Svensson, Lars Tanum, Torsten Gordh, Kim Kultima
Fibromyalgia (FM) is a syndrome characterized by widespread muscular pain, fatigue and functional symptoms, which is known to be difficult to diagnose as the various symptoms overlap with many other conditions. Currently, there are no biomarkers for FM, and the diagnosis is made subjectively by the clinicians. We have performed shotgun proteomics on cerebrospinal fluid (CSF) from FM patients and non-pain controls to find potential biomarker candidates for this syndrome. Based on our multivariate and univariate analyses, we found that the relative differences in the CSF proteome between FM patients and controls were moderate...
April 12, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29648891/muscular-and-vascular-issues-induced-by-prolonged-standing-with-different-work-rest-cycles-with-active-or-passive-breaks
#16
Maria-Gabriela Garcia, Thomas Läubli, Bernard J Martin
OBJECTIVE: The aim of this study was to evaluate the long-lasting motor, behavioral, physiological, and perceptual effects of prolonged standing work in three work-rest cycle conditions including passive or active rest breaks. BACKGROUND: Muscle fatigue has been evidenced after prolonged standing work through physiological and neuromotor measures. It has been postulated that muscle fatigue induced by prolonged work could be attenuated by appropriate scheduling of work and rest periods...
April 1, 2018: Human Factors
https://www.readbyqxmd.com/read/29643590/immediate-effects-of-transcutaneous-electrical-nerve-stimulation-on-six-minute-walking-test-borg-scale-questionnaire-and-hemodynamic-responses-in-patients-with-chronic-heart-failure
#17
Majid Ashraf Ganguie, Behrouz Attarbashi Moghadam, Nastaran Ghotbi, Azadeh Shadmehr, Mohammad Masoumi
[Purpose] This study examined the immediate effects of transcutaneous electrical nerve stimulation on a six-minute walking test, Borg scale questionnaire and hemodynamic responses in patients with chronic heart failure. [Subjects and Methods] Thirty patients with stable systolic chronic heart failure came to the pathophysiology laboratory three times. The tests were randomly performed in three sessions. In one session, current was applied to the quadriceps muscles of both extremities for 30 minutes and a six-minute walking test was performed immediately afterward...
December 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29614000/biomechanical-model-for-stress-fracture-related-factors-in-athletes-and-soldiers
#18
Amir Hadid, Yoram Epstein, Nogah Shabshin, Amit Gefen
Stress fractures (SFs) are one of the most common and potentially serious overuse injuries. PURPOSE: to develop a computational biomechanical model of strain in human tibial bone that will facilitate better understanding of the pathophysiology of SFs. METHODS: MRI of a healthy, young male, was used for full anatomical segmentation of the calf tissues, which considered hard-soft tissues biomechanical interactions. From the undeformed coronal MR images, the geometry of bones, muscles, connecting ligaments, and fat were reconstructed in three-dimensions, and meshed to a finite element model...
April 2, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29607736/muscle-activation-and-local-muscular-fatigue-during-a-12-minute-rotational-bridge
#19
Sally D Lark, James A Dickie, James A Faulkner, Matthew J Barnes
Due to anecdotal reports of back pain during a 12-minute rotational bridge test by uniformed services, the level of fatigue leading to possible back pain and or injury was investigated. We hypothesised a high level of fatigue due to diminishing core muscle activation. Nineteen highly trained uniformed service members were measured by surface electromyography of the rectus abdominis, external oblique, internal oblique, lumbar erector spinae, thoracic erector spinae and latissimus dorsi. Average rectified electromyography amplitude (AEMG) and median power frequency were analysed to determine activation and fatigue...
April 2, 2018: Sports Biomechanics
https://www.readbyqxmd.com/read/29599846/reference-values-for-fatigued-versus-non-fatigued-limb-symmetry-index-measured-by-a-newly-designed-single-leg-hop-test-battery-in-healthy-subjects-a-pilot-study
#20
Iris Leister, Georg Mattiassich, Harald Kindermann, Reinhold Ortmaier, Jürgen Barthofer, Imre Vasvary, Klaus Katzensteiner, Christine Stelzhammer, Stefan Tino Kulnik
Purpose: There is sparse evidence for return to sport criteria after knee injury. Functional performance deficits, particularly in fatigued muscular condition, should be verified prior to the attempt to return to high-risk pivoting sports. The purpose of this study was to generate reference values for the limb symmetry index (LSI) of healthy subjects in fatigued and non-fatigued muscular condition in a newly designed test battery. Methods: Forty-two healthy subjects [22 females, 20 males; mean (SD) age 30...
2018: Sport Sciences for Health
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