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Muscular fatigue

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https://www.readbyqxmd.com/read/29148135/cadence-tracking-and-disturbance-rejection-in-functional-electrical-stimulation-cycling-for-paraplegic-subjects-a-case-study
#1
Lucas O da Fonseca, Antônio P L Bó, Juliana A Guimarães, Miguel E Gutierrez, Emerson Fachin-Martins
Functional electrical stimulation cycling has been proposed as an assistive technology with numerous health and fitness benefits for people with spinal cord injury, such as improvement in cardiovascular function, increase in muscular mass, and reduction of bone mass loss. However, some limitations, for example, lack of optimal control strategies that would delay fatigue, may still prevent this technology from achieving its full potential. In this work, we performed experiments on a person with complete spinal cord injury using a stationary tadpole trike when both cadence tracking and disturbance rejection were evaluated...
November 2017: Artificial Organs
https://www.readbyqxmd.com/read/29142792/spinal-muscular-atrophy-the-treatment-approved
#2
Rabih Tabet, Sandy El Bitar, Julie Zaidan, Garbis Dabaghian
Spinal muscular atrophy (SMA) is a rare genetic neuromuscular disorder resulting in progressive muscle weakness and atrophy. It is universally fatal, especially if the respiratory muscles are involved leading to repetitive aspiration and respiratory failure. Historically, the treatment for this disease was only supportive. Herein we describe an adult patient who presented with worsening weakness and fatigue and was subsequently diagnosed with spinal muscular atrophy. Increased awareness of this condition and a new treatment modality is required...
September 2, 2017: Curēus
https://www.readbyqxmd.com/read/29127508/active-and-passive-recovery-influence-responses-of-luteinizing-hormone-and-testosterone-to-a-fatiguing-strength-loading
#3
R S Taipale, Heikki Kyröläinen, S S Gagnon, B Nindl, J Ahtiainen, K Häkkinen
The purpose of this study was to examine the acute hormonal and muscular responses to a strenuous strength loading [bilateral leg press (LP) 10 × 10 1RM] followed by loading-specific active (AR, n = 7, LP 10 × 10 × 30% 1RM) or passive (PR, n = 11, seated) recovery. The subjects were men age: 26 ± 4 years, height: 174 ± 8 cm, body mass: 75 ± 13 kg. After control measurements, experimental measurements were conducted at pre- and post-loading as well as post-recovery and next morning...
November 10, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29120978/effect-of-load-carriage-on-tactical-performance-in-swat-operators
#4
J Matthew Thomas, Michael B Pohl, Robert Shapiro, Jason Keeler, Mark G Abel
Special Weapons and Tactics (SWAT) operators are specially trained personnel that are required to carry equipment to perform high risk tasks. Given the need to carry this equipment, it is important to understand the potentially deleterious effect that the additional load may have on tactical performance. Furthermore, it is important to identify physical fitness characteristics that are associated with the potential decrement in performance. Therefore, the purpose of this study was to evaluate the effect of load carriage on tactical physical ability and marksmanship, and to identify fitness characteristics associated with any decrement in performance...
November 6, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29117428/change-in-knee-flexor-torque-after-fatiguing-exercise-identifies-previous-hamstring-injury-in-football-players
#5
Cameron Lord, Fadi Ma'ayah, Anthony J Blazevich
PURPOSE: Muscular fatigue and inter-limb strength asymmetry are factors known to influence hamstring injury risk, however limb-specific exacerbation of knee flexor (hamstrings) torque production after fatiguing exercise has previously been ignored. To investigate changes in muscular force production before and after sport-specific (repeated-sprint) and non-specific (knee extension-flexion) fatiguing exercise, and explore the sensitivity and specificity of isokinetic endurance (i.e. muscle-specific) and single-leg vertical jump (i...
November 8, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29116571/quality-of-life-in-adult-patients-with-limb-girdle-muscular-dystrophies
#6
Marina Peric, Stojan Peric, Jelena Stevanovic, Sara Milovanovic, Ivana Basta, Ana Nikolic, Aleksandra Kacar, Vidosava Rakocevic-Stojanovic
Although limb-girdle muscular dystrophies (LGMD) can cause permanent disability, to date there are no studies that examined quality of life (QoL) in these patients. Our aim was to evaluate QoL in patients with LGMD, and to identify the most significant predictors of QoL. The study comprised 46 patients with diagnosis of limb-girdle muscular weakness. QoL in patients was evaluated using two scales-SF-36 questionnaire and the Individualized Neuromuscular Quality of Life questionnaire (INQoL). Following scales were also applied: Epworth Sleepiness Scale (ESS), Hamilton Scale for Depression (HamD), and Krupp's Fatigue Severity Scale (FSS)...
November 7, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29099680/pre-exercise-infrared-photobiomodulation-therapy-810%C3%A2-nm-in-skeletal-muscle-performance-and-postexercise-recovery-in-humans-what-is-the-optimal-power-output
#7
Adriano Rodrigues de Oliveira, Adriane Aver Vanin, Shaiane Silva Tomazoni, Eduardo Foschini Miranda, Gianna Móes Albuquerque-Pontes, Thiago De Marchi, Vanessa Dos Santos Grandinetti, Paulo Roberto Vicente de Paiva, Treice Beatriz Gonçalves Imperatori, Paulo de Tarso Camillo de Carvalho, Jan Magnus Bjordal, Ernesto Cesar Pinto Leal-Junior
BACKGROUND: Photobiomodulation therapy (PBMT) has recently been used to alleviate postexercise muscle fatigue and enhance recovery, demonstrating positive results. A previous study by our research group demonstrated the optimal dose for an infrared wavelength (810 nm), but the outcomes could be optimized further with the determination of the optimal output power. OBJECTIVE: The aim of the present study was to evaluate the effects of PBMT (through low-level laser therapy) on postexercise skeletal muscle recovery and identify the best output power...
November 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29097109/hand-massage-for-cancer-patients-undergoing-chemotherapy-as-outpatients-a-pilot-study
#8
Susanne M Cutshall, Saswati Mahapatra, Rebecca S Hynes, Kimberly M Van Rooy, Sherry A Looker, Aditya Ghosh, Cathy D Schleck, Brent A Bauer, Dietlind L Wahner-Roedler
CONTEXT: There are no studies on the effect of volunteer-provided hand massage in a busy chemotherapy outpatient practice. OBJECTIVE: To assess the feasibility of introducing hand massage therapy into an outpatient chemotherapy unit and to evaluate the effect of the therapy on various symptoms experienced by cancer patients. DESIGN: A pilot, quasi-experimental, pretest-posttest study. SETTING: Chemotherapy outpatient clinic of a large tertiary care academic medical center...
August 25, 2017: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/29093790/perioperative-evaluation-of-respiratory-muscle-strength-after-scoliosis-correction-in-patients-with-duchenne-muscular-dystrophy
#9
Wataru Saito, Kosuke Mizuno, Gen Inoue, Takayuki Imura, Toshiyuki Nakazawa, Masayuki Miyagi, Eiki Shirasawa, Kentaro Uchida, Masashi Takaso
Study Design: Retrospective cohort study. Purpose: To investigate the effect of spinal correction on respiratory muscle strength in patients with Duchenne muscular dystrophy (DMD). Overview of Literature: Several studies have reported that scoliosis correction in patients with DMD does not improve pulmonary function. In these studies, pulmonary function was evaluated using the traditional spirometric values of percent vital capacity (%VC) and percent forced vital capacity (%FVC)...
October 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/29090398/photobiomodulation-therapy-for-the-improvement-of-muscular-performance-and-reduction-of-muscular-fatigue-associated-with-exercise-in-healthy-people-a-systematic-review-and-meta-analysis
#10
REVIEW
Adriane Aver Vanin, Evert Verhagen, Saulo Delfino Barboza, Leonardo Oliveira Pena Costa, Ernesto Cesar Pinto Leal-Junior
Researches have been performed to investigate the effects of phototherapy on improving performance and reduction of muscular fatigue. However, a great variability in the light parameters and protocols of the trials are a concern to establish the efficacy of this therapy to be used in sports or clinic. The aim of this study is to investigate the effectiveness, moment of application of phototherapy within an exercise protocol, and which are the parameters optimally effective for the improvement of muscular performance and the reduction of muscular fatigue in healthy people...
October 31, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29064297/updating-the-risk-index-a-systematic-review-and-meta-analysis-of-occupational-injuries-and-work-schedule-characteristics
#11
Dorothee Fischer, David A Lombardi, Simon Folkard, Joanna Willetts, David C Christiani
Fatigue is a major risk factor for occupational 'accidents' and injuries, and involves dimensions of physical, mental, and muscular fatigue. These dimensions are largely influenced by temporal aspects of work schedules. The "Risk Index" combines four fatigue-related components of work schedules to estimate occupational 'accident' and injury risk based on empirical trends: shift type (morning, afternoon/evening, night), length and consecutive number, and on-shift rest breaks. Since its first introduction in 2004, several additional studies have been published that allow the opportunity to improve the internal and external validity of the "Risk Index"...
October 24, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29060120/heart-rate-variability-analysis-during-muscle-fatigue-due-to-prolonged-isometric-contraction
#12
Andrea Guidi, Alberto Greco, Federica Felici, Andrea Leo, Emiliano Ricciardi, Matteo Bianchi, Antonio Bicchi, Gaetano Valenza, Enzo Pasquale Scilingo
Fatigue can be defined as the muscular condition occurring before the inability to perform a task. It can be assessed through the evaluation of the median and mean frequency of the spectrum of the surface electromyography series. Previous studies investigated the relationship between heartbeat dynamics and muscular activity. However, exploitation of such cardiovascular measures to automatically identify muscle fatigue during fatiguing exercises is still missing. To this extent, HRV signals were gathered from 32 subjects during an isometric contraction task, and features defined in the time, frequency and nonlinear domains were investigated...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29038526/strain-in-shock-loaded-skeletal-muscle-and-the-time-scale-of-muscular-wobbling-mass-dynamics
#13
Kasper B Christensen, Michael Günther, Syn Schmitt, Tobias Siebert
In terrestrial locomotion, muscles undergo damped oscillations in response to limb impacts with the ground. Muscles are also actuators that generate mechanical power to allow locomotion. The corresponding elementary contractile process is the work stroke of an actin-myosin cross-bridge, which may be forcibly detached by superposed oscillations. By experimentally emulating rat leg impacts, we found that full activity and non-fatigue must meet to possibly prevent forcible cross-bridge detachment. Because submaximal muscle force represents the ordinary locomotor condition, our results show that forcible, eccentric cross-bridge detachment is a common, physiological process even during isometric muscle contractions...
October 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29023324/the-physical-response-to-a-simulated-period-of-soccer-specific-fixture-congestion
#14
Richard M Page, Kelly Marrin, Chris M Brogden, Matt Greig
The aim of this study was to assess the physiological, perceptual, and mechanical measures associated with the completion of a simulated period of short-term soccer-specific fixture congestion. Ten male semi-professional soccer players completed three trials of a treadmill-based match simulation, with 48 hours intervening each trial. A repeated measures general linear model identified significantly (P= 0.02) lower knee flexor peak torque (PT) recorded at 300 degs[BULLET OPERATOR]s in the second (141.27 ± 28...
October 10, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28991036/no-effect-of-%C3%AE-alanine-on-muscle-function-and-kayak-performance
#15
Signe Refsgaard Bech, Tobias Schmidt Nielsen, Martin Hald, Jarl Pors Jakobsen, Nikolai Baastrup Nordsborg
PURPOSE: It was investigated if β-alanine supplementation counteracts muscular fatigue development or improves athletic performance. METHODS: Elite kayak rowers (10 males and 7 females) were supplemented with either 80 mg/kg body mass/day β-alanine or placebo for 8 weeks. Muscular fatigue development was investigated by applying a 2 min elbow flexor maximal voluntary contraction (MVC). Electromyography (EMG) was recorded continuously and voluntary activation (VA) was determined 30, 60, 90 and 115 s into the 2 min MVC...
October 5, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28983275/cortical-substrate-of-supraspinal-fatigue-following-exhaustive-aerobic-exercise-localizes-to-a-large-cluster-in-the-anterior-premotor-cortex
#16
Priyantha Herath, Martin Carmichael, Angela Murphy, Leonardo Bonilha, Roger Newman-Norlund, Chris Rorden, Mark Davis
Strenuous exercise leads to a progressive reduction in the performance of voluntary physical exercise. This is due to a process described as fatigue and is defined as the failure to maintain the required or expected power output. While some of this is muscular in origin, there are data suggestive of how fatigue is modulated by cortical signals, leading to a concept of central fatigue. The previously reported fatigue-induced changes in cortical activity may have been due to blood oxygen-dependent (BOLD) signal drift and/or neural habituation alone...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28969183/meropenem-induced-hypokalemia
#17
T V Anuhya, Raviraj Acharya, Sharath MadhyasthaA, Ram Bhat, Veena Nayak
Meropenam, a beta-lactam antibiotic has been used for severe infections of skin, tissue, intra- abdominal and urogenital infections in hospitalized patients. The common adverse effects reported are diarrhoea, vomiting, rashes and hypersensitivity reactions. Here we report two cases of meropenam induced hypokalemia, wherein, meropenam was prescribed for cellulitis and urinary tract infection in the first and second case respectively. Hypokalemia can manifest as muscular weakness, fatigue, muscle cramps, constipation, ileus, flaccid paralysis, hyporeflexia, hypercapnia, tetany, rhabdomyolysis or respiratory failure...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28941657/effects-of-a-complex-rehabilitation-program-on-edema-status-physical-function-and-quality-of-life-in-lower-limb-lymphedema-after-gynecological-cancer-surgery
#18
RANDOMIZED CONTROLLED TRIAL
Jung Hwa Do, Kyoung Hyo Choi, Jun Su Ahn, Jae Yong Jeon
OBJECTIVE: The purpose of this study was to investigate the effects of a complex rehabilitation (CR) program and complex decongestive therapy (CDT) on edema status, physical function, and quality of life in patients with unilateral lower-limb lymphedema after gynecologic cancer surgery. METHODS: In this randomized pilot study, 40 patients with secondary unilateral lymphedema, after gynecologic surgery for cervical, endometrial, or ovarian cancer, that had been diagnosed based on clinical assessment and 10% volume differences between the legs were randomly assigned to the CDT (n=20) and CDT combined with CR (CRCDT; n=20) groups...
November 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28940089/skeletal-muscle-alterations-in-hfref-vs-hfpef
#19
REVIEW
Volker Adams, Axel Linke, Ephraim Winzer
PURPOSE OF REVIEW: Severe exercise intolerance and early fatigue are hallmarks of heart failure patients either with a reduced (HFrEF) or a still preserved (HFpEF) ejection fraction. This review, therefore, will provide a contemporary summary of the alterations currently known to occur in the skeletal muscles of both HFrEF and HFpEF, and provide some further directions that will be required if we want to improve our current understanding of this area. RECENT FINDINGS: Skeletal muscle alterations are well documented for over 20 years in HFrEF, and during the recent years also data are presented that in HFpEF muscular alterations are present...
December 2017: Current Heart Failure Reports
https://www.readbyqxmd.com/read/28939592/%C3%AE-ketoglutarate-prevents-skeletal-muscle-protein-degradation-and-muscle-atrophy-through-phd3-adrb2-pathway
#20
Xingcai Cai, Yexian Yuan, Zhengrui Liao, Kongping Xing, Canjun Zhu, Yaqiong Xu, Lulu Yu, Lina Wang, Songbo Wang, Xiaotong Zhu, Ping Gao, Yongliang Zhang, Qingyan Jiang, Pingwen Xu, Gang Shu
Skeletal muscle atrophy due to excessive protein degradation is the main cause for muscle dysfunction, fatigue, and weakening of athletic ability. Endurance exercise is effective to attenuate muscle atrophy, but the underlying mechanism has not been fully investigated. α-Ketoglutarate (AKG) is a key intermediate of tricarboxylic acid cycle, which is generated during endurance exercise. Here, we demonstrated that AKG effectively attenuated corticosterone-induced protein degradation and rescued the muscle atrophy and dysfunction in a Duchenne muscular dystrophy mouse model...
September 22, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
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