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https://www.readbyqxmd.com/read/29141397/supporting-low-income-cancer-patients-recommendations-for-the-public-financial-aid-program-in-the-republic-of-korea
#1
Hye Sook Min, Hyung Kook Yang, Keeho Park
Purpose: As the recent term of "financial toxicity" implies, cancer causes a treatment-related financial harm. Financial Aid Program for Cancer Patient (FAPCP) is a government's financial support for low-income patients in the Republic of Korea. This study aimed to describe FAPCP applicants' condition and to investigate factors influencing financial burden, which would provide the basis for implementing a strategy for FAPCP administration. Materials and Methods: The telephone survey results from 2,700 FAPCP participants were analyzed, including demographic, socioeconomic, and disease characteristics and experiences associated with financial burden and the actions or measures to cope with them...
November 15, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/29139056/ensuring-implementation-fidelity-of-a-10-week-home-visiting-program-in-two-randomized-clinical-trials
#2
Monica L Oxford, Susan J Spieker, Mary Jane Lohr, Charles B Fleming, Colleen Dillon, Jennifer Rees
Introduction Implementation fidelity is a challenge for the adoption of evidence-based programs within social service broadly and child welfare specifically. However, implementation fidelity is critical for maintaining the integrity of clinical trials and for ensuring successful delivery of services in public health settings. Methods Promoting First Relationships (®) (PFR), a 10-week home visiting parenting intervention, was evaluated in two randomized clinical trials with populations of families in child welfare...
November 14, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29138765/sizing-sub-diffraction-limit-electrosprayed-droplets-by-structured-illumination-microscopy
#3
Adam Hollerbach, David Logsdon, Kiran Iyer, Anyin Li, J Andy Schaber, R Graham Cooks
Electrosprayed droplets are widely studied for their role in the formation of ions at atmospheric pressure. Most droplet measurement methods used today employ light scattering to infer information about an electrosprayed droplet's size. However, these methods fail to measure droplets smaller than about 400 nm in diameter due to constraints imposed by the diffraction limit of light. To overcome this limitation, a super resolution fluorescence microscopy-based method for determining the sizes of electrosprayed droplets has been developed...
November 15, 2017: Analyst
https://www.readbyqxmd.com/read/29138497/rapid-purification-of-human-bispecific-antibodies-via-selective-modulation-of-protein-a-binding
#4
Adam Zwolak, Catherine N Leettola, Susan H Tam, Dennis R Goulet, Mehabaw G Derebe, Jose R Pardinas, Songmao Zheng, Rose Decker, Eva Emmell, Mark L Chiu
Methods to rapidly generate high quality bispecific antibodies (BsAb) having normal half-lives are critical for therapeutic programs. Here, we identify 3 mutations (T307P, L309Q, and Q311R or "TLQ") in the Fc region of human IgG1 which disrupt interaction with protein A while enhancing interaction with FcRn. The mutations are shown to incrementally alter the pH at which a mAb elutes from protein A affinity resin. A BsAb comprised of a TLQ mutant and a wild-type IgG1 can be efficiently separated from contaminating parental mAbs by differential protein A elution starting from either a) purified parental mAbs, b) in-supernatant crossed parental mAbs, or c) co-transfected mAbs...
November 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29136116/prenatal-stress-glucocorticoids-and-developmental-programming-of-the-stress-response
#5
Patrick O McGowan, Stephen G Matthews
The early environment has a major impact on the developing embryo, fetus and infant. Parental adversity (maternal and paternal) and glucocorticoid exposure prior to conception and during pregnancy have profound effects on the development and subsequent function of the hypothalamic-pituitary-adrenal (HPA) axis and related behaviours. These effects are species-, sex- and age-specific, and depend on the timing and duration of exposure. The impact of these early exposures can extend across multiple generations, via both the maternal and paternal lineage, and recent studies have begun to determine the mechanisms by which this occurs...
November 10, 2017: Endocrinology
https://www.readbyqxmd.com/read/29135696/effect-of-a-scenario-tailored-opioid-messaging-program-on-parents-risk-perceptions-and-opioid-decision-making
#6
Terri Voepel-Lewis, Brian J Zikmund-Fisher, Carol J Boyd, Philip T Veliz, Sean Esteban McCabe, Monica Weber, Alan R Tait
OBJECTIVES: Poor parental understanding of prescription opioid risks is associated with potentially dangerous decisions that can contribute to adverse drug events (ADE) in children and adolescents. This study examined whether an interactive Scenario-Tailored Opioid Messaging Program (STOMP™) would (1) enhance opioid risk perceptions and (2) improve the safety of parents' decision-making. METHODS: 546 parents were randomized to receive the STOMP™ versus Control information and 516 completed the program...
November 10, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29134133/monitoring-and-morphologic-classification-of-pediatric-cataract-using-slit-lamp-adapted-photography
#7
Erping Long, Zhuoling Lin, Jingjing Chen, Zhenzhen Liu, Qianzhong Cao, Haotian Lin, Weirong Chen, Yizhi Liu
Purpose: To investigate the feasibility of pediatric cataract monitoring and morphologic classification using slit lamp-adapted anterior segmental photography in a large cohort that included uncooperative children. Methods: Patients registered in the Childhood Cataract Program of the Chinese Ministry of Health were prospectively selected. Eligible patients underwent slit-lamp adapted anterior segmental photography to record and monitor the morphology of their cataractous lenses...
November 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/29133798/motivational-interviewing-and-urine-cotinine-feedback-to-stop-passive-smoke-exposure-in-children-predisposed-to-asthma-a-randomised-controlled-trial
#8
Sasha G Hutchinson, Gerard van Breukelen, Constant P van Schayck, Brigitte Essers, S Katharine Hammond, Jean W M Muris, Frans J M Feron, Edward Dompeling
We tested the effectiveness of a program consisting of motivational interviewing (MI) and feedback of urine cotinine to stop passive smoking (PS) in children at risk for asthma. Fifty-eight families with children 0-13 years with a high risk of asthma and PS exposure were randomised in a one-year follow-up study. The intervention group received the intervention program during 6 sessions (1/month) and the control group received measurements (questionnaires, urine cotinine, and lung function) only. The primary outcome measure was the percentage of families stopping PS (parental report verified and unverified with the child's urine cotinine concentration <10 μg/l) in children during the intervention program...
November 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29132060/traditional-beliefs-and-practices-in-pregnancy-childbirth-and-postpartum-a-review-of-the-evidence-from-asian-countries
#9
Mellissa Withers, Nina Kharazmi, Esther Lim
INTRODUCTION: Asian women suffer the largest proportion of the world's maternal deaths. To reduce this, policymakers and healthcare providers must encourage women with traditionally low rates of maternal health care utilization to access services. OBJECTIVE: The purpose of this study is to provide a comprehensive review of the most common traditional practices in Asia relating to pregnancy, childbirth and the postpartum period. DESIGN: We conducted a literature search of articles: a) focusing on Asia; b) relating to pregnancy, childbirth or postpartum, c) relating to traditional beliefs and/or cultural practices; and 4) published in English in the year 2000 or more recently...
November 10, 2017: Midwifery
https://www.readbyqxmd.com/read/29128379/active-sms-based-influenza-vaccine-safety-surveillance-in-australian-children
#10
Alexis Pillsbury, Helen Quinn, Patrick Cashman, Alan Leeb, Kristine Macartney
INTRODUCTION: Australia's novel, active surveillance system, AusVaxSafety, monitors the post-market safety of vaccines in near real time. We analysed cumulative surveillance data for children aged 6 months to 4 years who received seasonal influenza vaccine in 2015 and/or 2016 to determine: adverse event following immunisation (AEFI) rates by vaccine brand, age and concomitant vaccine administration. METHODS: Parent/carer reports of AEFI occurring within 3 days of their child receiving an influenza vaccine in sentinel immunisation clinics were solicited by Short Message Service (SMS) and/or email-based survey...
November 8, 2017: Vaccine
https://www.readbyqxmd.com/read/29127208/effectiveness-of-a-kindergarten-based-intervention-for-preventing-childhood-obesity
#11
Yan Hu, Jian-Rong He, Fang-Hua Liu, Wei-Dong Li, Jin-Hua Lu, Yan-Fei Xing, Sui-Fang Lin, Xian Liu, Suzanne Bartington, Qiong Feng, Hui-Min Xia, Kin Bong Hubert Lam, Kar Keung Cheng, Xiu Qiu
BACKGROUND AND OBJECTIVES: Interventions to prevent childhood obesity targeting school age children have mostly reported limited effectiveness, suggesting such prevention programs may need to start at an earlier age, but evidence has been scarce. We reported a pilot study aiming to demonstrate the feasibility of a multifaceted intervention for preschool children and to provide a preliminary assessment of the effectiveness. METHODS: This nonrandomized controlled trial recruited children aged 3 to 6 years from 6 kindergartens in Guangzhou, China...
November 10, 2017: Pediatrics
https://www.readbyqxmd.com/read/29125906/narrative-review-of-the-educational-vocational-and-financial-needs-of-adolescents-and-young-adults-with-cancer-recommendations-for-support-and-research
#12
Joanna E Fardell, Claire E Wakefield, Pandora Patterson, Alistair Lum, Richard J Cohn, Simon A Pini, Ursula M Sansom Daly
Adolescents and young adults (AYAs) with cancer have unique needs around education and vocation during and after treatment. This narrative review series aims at documenting the unique needs of AYAs from the current literature and at providing recommendations to inform an update of the Australian National Service Delivery Framework for AYAs with Cancer. AYAs with cancer may experience impairments to cognitive, physical, and psychological functioning and health, which can adversely affect their academic grades, peer relationships, and likelihood of entering the workforce...
November 10, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29123537/association-mapping-of-ferrous-zinc-and-aluminum-tolerance-at-the-seedling-stage-in-indica-rice-using-magic-populations
#13
Lijun Meng, Baoxiang Wang, Xiangqian Zhao, Kimberly Ponce, Qian Qian, Guoyou Ye
Excessive amounts of metal are toxic and severely affect plant growth and development. Understanding the genetic control of metal tolerance is crucial to improve rice resistance to Fe, Zn, and Al toxicity. The multi-parent advanced generation inter-cross (MAGIC) populations were genotyped using a 55 K rice SNP array and screened at the seedling stage for Fe, Zn, and Al toxicity using a hydroponics system. Association analysis was conducted by implementing a mixed linear model (MLM) for each of the five MAGIC populations double cross DC1 (founders were SAGC-08, HHZ5-SAL9-Y3-Y1, BP1976B-2-3-7-TB-1-1, PR33282-B-8-1-1-1-1-1), double cross DC2 (founders of double cross were FFZ1, CT 16658-5-2-2SR-2-3-6MP, IR 68, IR 02A127), eight parents population 8way (founders were SAGC-08, HHZ5-SAL9-Y3-Y1, BP1976B-2-3-7-TB-1-1, PR33282-B-8-1-1-1-1-1, FFZ1, CT 16658-5-2-2SR-2-3-6MP, IR 68, IR 02A127), DC12 (DC1+DC2) and rice multi-parent recombinant inbred line population RMPRIL (DC1+DC2+8way)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29121791/unexpected-survivors-children-with-life-limiting-conditions-of-uncertain-prognosis
#14
Savithri Nageswaran, Anna Hurst, Andrea Radulovic
OBJECTIVE: Prognostication of survival is difficult in children with life-limiting illnesses because of the rarity of these conditions and technological advances improving survival. The objective of this article is to describe the characteristics of children with life-limiting illnesses who survived longer than the expectations of health-care providers. STUDY DESIGN: This is a retrospective cohort study conducted in a tertiary-care children's hospital in North Carolina...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/29121494/being-a-mother-of-preterm-multiples-in-the-context-of-socioeconomic-disadvantage-perceived-stress-and-psychological-symptoms
#15
Joana Baptista, Vanessa Moutinho, Vera Mateus, Hercília Guimarães, Fátima Clemente, Sara Almeida, Maria Agostinha Andrade, Clara Paz Dias, Alice Freitas, Carla Martins, Isabel Soares
OBJECTIVE: This study aimed to examine the differences between mothers of preterm multiples and mothers of preterm singletons regarding perceived stress and maternal psychological symptoms, and to explore the putative adverse amplified effect of socioeconomic disadvantage. METHOD: Ninety-five mothers of 1-year-olds born preterm participated in this cross-sectional study. Data collection was carried out in two public hospitals from Northern Portugal. To assess maternal perceived daily stress and psychological symptoms, mothers completed two questionnaires...
November 6, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/29121492/the-association-of-parental-obesity-with-physical-activity-and-sedentary-behaviors-of-their-children-the-caspian-v-study
#16
Pooneh Angoorani, Ramin Heshmat, Hanieh-Sadat Ejtahed, Mohammad Esmaeil Motlagh, Hasan Ziaodini, Majzoubeh Taheri, Tahereh Aminaee, Gita Shafiee, Azam Goodarzi, Mostafa Qorbani, Roya Kelishadi
OBJECTIVE: Low physical activity and sedentary behaviors, two important determinants of childhood obesity, may be influenced by parental lifestyle and weight status. This study aims to determine the association of parental weight status with children's physical activity and screen time. METHODS: This study was conducted on 14,440 Iranian schools students, aged 7-18 years, and one of their parents, who participated in the large national school-based surveillance program...
November 6, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/29121432/effectiveness-of-alpine-climate-treatment-for-children-with-difficult-to-treat-atopic-dermatitis-results-of-a-pragmatic-randomized-controlled-trial-davos-trial
#17
Karin Fieten, Renske Schappin, Wieneke Zijlstra, Lilian Figee, Jos Beutler, Florine Raymakers, Harmieke van Os-Medendorp, Rebecca Stellato, Maartje Vandewall, Joan Winkelhof, Monica Uniken Venema, Carla Bruijnzeel-Koomen, Lucia Rijssenbeek-Nouwens, Cornelis van der Ent, Els van Hoffen, Yolanda Meijer, Suzanne Pasmans
BACKGROUND: Alpine climate treatment has historically been used in Europe to treat atopic dermatitis (AD), but no randomized trials have been conducted to provide evidence for its effectiveness. OBJECTIVE: To investigate the long-term effectiveness of alpine climate treatment for children with difficult to treat AD. MATERIALS & METHODS: A pragmatic, open, randomized controlled trial was conducted. Children diagnosed with AD that was considered difficult to treat, aged between 8 and 18 years and willing to be treated in Switzerland were randomized to a six week personalized integrative multidisciplinary treatment period in a clinical setting in the alpine climate (Switzerland) or an outpatient setting in moderate maritime climate (Netherlands)...
November 9, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29121111/genetic-and-physical-mapping-of-anther-extrusion-in-elite-european-winter-wheat
#18
Quddoos H Muqaddasi, Klaus Pillen, Jörg Plieske, Martin W Ganal, Marion S Röder
The production and cultivation of hybrid wheat is a possible strategy to close the yield gap in wheat. Efficient hybrid wheat seed production largely depends on high rates of cross-pollination which can be ensured through high anther extrusion (AE) by male parental lines. Here, we report the AE capacity and elucidate its genetics in 514 elite European winter wheat varieties via genome-wide association studies (GWAS). We observed a wide range of variation among genotypes and a high heritability (0.80) for AE...
2017: PloS One
https://www.readbyqxmd.com/read/29119741/supervised-toothbrushing-programs-in-primary-schools-and-early-childhood-settings-a-scoping-review
#19
V Dickson-Swift, A Kenny, M Gussy, A M de Silva, J Farmer, S Bracksley-O'Grady
OBJECTIVE: In this article we report the findings of a scoping review that aimed to identify and summarise the range of programs and guidelines available for toothbrushing programs in schools and early childhood settings. Dental caries is one of the most common preventable diseases affecting children worldwide. Untreated caries can impact on child health and wellbeing, development, socialisation and school attendance. Supervised toothbrushing programs in schools and other early childhood settings can be effective in improving the oral health of young children...
November 10, 2017: Community Dental Health
https://www.readbyqxmd.com/read/29119478/after-the-demonstration-what-states-sustained-after-the-end-of-federal-grants-to-improve-children-s-health-care-quality
#20
Henry T Ireys, Cindy Brach, Grace Anglin, Kelly J Devers, Rachel Burton
Introduction Under the CHIPRA Quality Demonstration Grant Program, CMS awarded $100 million through 10 grants that 18 state Medicaid agencies implemented between 2010 and 2015. The program's legislatively-mandated purpose was to evaluate promising ideas for improving the quality of children's health care provided through Medicaid and CHIP. As part of the program's multifaceted evaluation, this study examined the extent to which states sustained key program activities after the demonstration ended. Methods We identified 115 potentially sustainable elements within states' CHIPRA demonstrations and analyzed data from grantee reports and key informant interviews to assess sustainment outcomes and key influential factors...
November 8, 2017: Maternal and Child Health Journal
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