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https://www.readbyqxmd.com/read/28710686/-ophthalmological-assessment-in-the-severely-handicapped-persons-act-and-in-blindness-statement-of-the-professional-association-of-ophthalmologists-germany-the-german-ophthalmological-society-processed-by-the-joint-commission-on-law-status-january-2017
#1
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
July 14, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28696878/asynchronous-pumping-of-a-pulsatile-ventricular-assist-device-in-a-pediatric-anastomosis-model
#2
Bryan C Good, William J Weiss, Steven Deutsch, Keefe B Manning
BACKGROUND: Both pulsatile and continuous flow ventricular assist devices are being developed for pediatric congenital heart defect patients. Pulsatile devices are often operated asynchronously with the heart in either an "automatic" or a fixed beat rate mode. However, most studies have only investigated synchronized ejection. METHODS: A previously validated viscoelastic blood solver is used to investigate the parameters of pulsatility, power loss, and graft failure in a pediatric aortic anastomosis model...
July 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28693852/using-simulation-to-improve-systems
#3
REVIEW
James A Kearney, Ellen S Deutsch
Attempts to understand and improve health care delivery often focus on the characteristics of the patient and the characteristics of the health care providers, but larger systems surround and integrate with patients and providers. Components of health care delivery systems can support or interfere with efforts to provide optimal health care. Simulation in situ, involving real teams participating in simulations in real care settings, can be used to identify latent safety threats and improve the work environment while simultaneously supporting participant learning...
July 7, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28693583/prevention-of-seasonal-affective-disorder-in-daily-clinical-practice-results-of-a-survey-in-german-speaking-countries
#4
B Nussbaumer-Streit, D Winkler, M Spies, S Kasper, E Pjrek
BACKGROUND: Seasonal affective disorder (SAD) is a seasonally recurrent type of major depression. This predictable aspect makes it promising for preventive treatment. However, evidence for the efficacy and harm of preventive treatment of SAD is scarce, as are recommendations from clinical practice guidelines. The aim of this study was to assess the current use of preventive treatment of SAD in clinical practice in German-speaking countries for the first time. METHODS: We conducted a postal and web-based survey sent to the heads of all psychiatric institutions listed in the inventory "Deutsches Krankenhaus Adressbuch, 2015" that contains all psychiatric hospitals in Germany, Austria, and Switzerland...
July 11, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28692373/wound-dressings
#5
C J Deutsch, D M Edwards, S Myers
No abstract text is available yet for this article.
July 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28692006/brain-signature-and-functional-impact-of-centralized-pain-a-multidisciplinary-approach-to-the-study-of-chronic-pelvic-pain-mapp-network-study
#6
Jason J Kutch, Eric Ichesco, Johnson P Hampson, Jennifer S Labus, Melissa A Farmer, Katherine T Martucci, Timothy J Ness, Georg Deutsch, A Vania Apkarian, Sean C Mackey, David J Klumpp, Anthony J Schaeffer, Larissa V Rodriguez, Karl J Kreder, Dedra Buchwald, Gerald L Andriole, H Henry Lai, Chris Mullins, John W Kusek, J Richard Landis, Emeran A Mayer, J Quentin Clemens, Daniel J Clauw, Richard E Harris
Chronic pain is often measured with a severity score that overlooks its spatial distribution across the body. This widespread pain is thought to be a marker of centralization, a central nervous system process that decouples pain perception from nociceptive input. Here, we investigated whether centralization is manifested at the level of the brain using data from 1079 participants in the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network (MAPP) study. Participants with a clinical diagnosis of urological chronic pelvic pain syndrome (UCPPS) were compared to pain-free controls and fibromyalgia patients, the prototypical centralized pain disorder...
June 30, 2017: Pain
https://www.readbyqxmd.com/read/28688683/predictive-and-prognostic-value-of-ct-based-radiomics-signature-in-locally-advanced-head-and-neck-cancers-patients-treated-with-concurrent-chemoradiotherapy-or-bioradiotherapy-and-its-added-value-to-human-papillomavirus-status
#7
Dan Ou, Pierre Blanchard, Silvia Rosellini, Antonin Levy, France Nguyen, Ralph T H Leijenaar, Ingrid Garberis, Philippe Gorphe, François Bidault, Charles Ferté, Charlotte Robert, Odile Casiraghi, Jean-Yves Scoazec, Philippe Lambin, Stephane Temam, Eric Deutsch, Yungan Tao
OBJECTIVES: To explore prognostic and predictive value of radiomics in patients with locally advanced head and neck squamous cell carcinomas (LAHNSCC) treated with concurrent chemoradiotherapy (CRT) or bioradiotherapy (BRT). MATERIALS AND METHODS: Data of 120 patients (CRT vs. BRT matched 2:1) were retrospectively analyzed. A total of 544 radiomics features of the primary tumor were extracted from radiotherapy planning computed tomography scans. Cox proportional hazards models were used to examine the association between survival and radiomics features with false discovery rate correction...
August 2017: Oral Oncology
https://www.readbyqxmd.com/read/28687474/alfaxalone-for-maintenance-of-anaesthesia-in-ponies-undergoing-field-castration-continuous-infusion-compared-with-intravenous-boluses
#8
Julia Deutsch, Abel Ekiri, Annemarie de Vries
OBJECTIVE: To compare alfaxalone as continuous intravenous (IV) infusion with intermittent IV injections for maintenance of anaesthesia in ponies undergoing castration. STUDY DESIGN: Prospective, randomized, 'blinded' clinical study. ANIMALS: A group of 33 entire male Welsh ponies undergoing field castration. METHODS: After preanaesthetic medication with IV detomidine (10 μg kg(-1)) and butorphanol (0.05 mg kg(-1)), anaesthesia was induced with IV diazepam (0...
April 14, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28684240/intramuscular-injection-of-alfaxalone-in-combination-with-butorphanol-for-sedation-in-cats
#9
Julia Deutsch, Colette Jolliffe, Emma Archer, Elizabeth A Leece
OBJECTIVE: To assess quality of sedation following intramuscular (IM) injection of two doses of alfaxalone in combination with butorphanol in cats. STUDY DESIGN: Prospective, randomized, 'blinded' clinical study. ANIMALS: A total of 38 cats undergoing diagnostic imaging or noninvasive procedures. METHODS: Cats were allocated randomly to be administered butorphanol 0.2 mg kg(-1) combined with alfaxalone 2 mg kg(-1) (group AB2) or 5 mg kg(-1) (group AB5) IM...
March 6, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28676740/modulation-of-illusory-auditory-perception-by-transcranial-electrical-stimulation
#10
Giulia Prete, Anita D'Anselmo, Luca Tommasi, Alfredo Brancucci
The aim of the present study was to test whether transcranial electrical stimulation can modulate illusory perception in the auditory domain. In two separate experiments we applied transcranial Direct Current Stimulation (anodal/cathodal tDCS, 2 mA; N = 60) and high-frequency transcranial Random Noise Stimulation (hf-tRNS, 1.5 mA, offset 0; N = 45) on the temporal cortex during the presentation of the stimuli eliciting the Deutsch's illusion. The illusion arises when two sine tones spaced one octave apart (400 and 800 Hz) are presented dichotically in alternation, one in the left and the other in the right ear, so that when the right ear receives the high tone, the left ear receives the low tone, and vice versa...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28675953/utility-of-nociceptive-flexion-reflex-threshold-and-bispectral-index-to-predict-movement-responses-under-propofol-anaesthesia
#11
Axel Jakuscheit, Matthias J Posch, Stefanos Gkaitatzis, Lisa Neumark, Mark Hackbarth, Martin Schneider, Gregor Lichtner, Jan H Baars, Falk von Dincklage
INTRODUCTION: The nociceptive flexion reflex threshold (NFRT) is a promising tool to monitor analgesia during general anaesthesia. Clinical studies have shown that the NFRT allows to predict movement responses to painful stimuli under a combined anaesthetic regime of sedative and opioid agents. Experimental studies indicated that the NFRT is also able to predict such movement responses under an exclusively sedative regime like propofol mono-anaesthesia. Therefore, we performed this study to investigate the ability of the NFRT to predict movement responses to painful stimuli in patients during a clinical propofol mono-anaesthesia...
July 4, 2017: Somatosensory & Motor Research
https://www.readbyqxmd.com/read/28673762/diffusion-weighted-mri-in-image-guided-adaptive-brachytherapy-tumor-delineation-feasibility-study-and-comparison-with-gec-estro-guidelines
#12
Antoine Schernberg, Corinne Balleyguier, Isabelle Dumas, Sébastien Gouy, Alexandre Escande, Enrica Bentivegna, Philippe Morice, Eric Deutsch, Christine Haie-Meder, Cyrus Chargari
PURPOSE: To examine the feasibility of using diffusion-weighted images (DWIs) coregistered with T2-weighted (T2w) sequence in treatment planning system to improve target delineation for image-guided adaptive brachytherapy (IGABT) in locally advanced cervical cancer patients. METHODS AND MATERIALS: We retrospectively examined the records of consecutive patients who were referred to our institution for pulse-dose-rate IGABT between May and December 2015 after concurrent chemoradiation...
June 30, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28666454/fluorescence-optical-imaging-and-musculoskeletal-ultrasonography-in-juvenile-idiopathic-polyarticular-disease-before-and-during-antirheumatic-treatment%C3%A2-a-multicenter-non-interventional-diagnostic-evaluation
#13
Ariane Klein, Georg Werner Just, Stephanie Gabriele Werner, Prasad T Oommen, Kirsten Minden, Ingrid Becker, Hans-Eckhard Langer, Dirk Klee, Gerd Horneff
BACKGROUND: Valid detection of inflamed joints is essential for correct classification, therapeutic decisions, prognosis and assessment of treatment efficacy in juvenile idiopathic arthritis (JIA). Fluorescence optical imaging (FOI) enables visualization of inflammation in arthritis of finger and hand joints and might be used for monitoring. METHODS: A 24-week observational study in polyarticular JIA patients newly starting treatment with methotrexate or an approved biologic was performed in three centers...
June 30, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28662871/external-validation-of-leukocytosis-and-neutrophilia-as-a-prognostic-marker-in-anal-carcinoma-treated-with-definitive-chemoradiation
#14
Antoine Schernberg, Florence Huguet, Laurence Moureau-Zabotto, Cyrus Chargari, Eleonor Rivin Del Campo, Michel Schlienger, Alexandre Escande, Emmanuel Touboul, Eric Deutsch
PURPOSE: To validate the prognostic value of leukocyte disorders in anal squamous cell carcinoma (SCC) patients receiving definitive concurrent chemoradiation. MATERIALS AND METHODS: Bi-institutional clinical records from consecutive patients treated between 2001 and 2015 with definitive chemoradiation for anal SCC were retrospectively reviewed. Prognostic value of pretreatment leukocyte disorders was examined, with focus on patterns of relapse and survival. Leukocytosis and neutrophilia were defined as leukocyte or neutrophil count exceeding 10G/L and 7G/L, respectively...
June 26, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28662624/interference-between-family-caregivers-mental-disorders-and-their-estimates-of-quality-of-dying-and-death-qodd-of-their-loved-ones
#15
Maria Heckel, Sonja Bussmann, Martin Weber, Christoph Ostgathe, Stephanie Stiel
BACKGROUND: In studies enrolling informal caregivers of patients in palliative care, it is necessary to ensure that findings are not influenced by factors such as mental disorders. AIM: This study aims to describe the influence of anxiety and depression on bereaved informal caregivers' retrospective ratings of the quality of dying and death (QoDD) of their loved ones. DESIGN: Informal caregivers of deceased patients from 2 German palliative care (PC) units took part in a validation study of the German version of the original QoDD-Deutsch-Angehörige (QoDD-D-Ang) during the fourth week following the patient's death at the earliest...
January 2017: Journal of Palliative Care
https://www.readbyqxmd.com/read/28661911/pump-in-parallel-mechanical-assistance-of-partial-cavopulmonary-circulation-using-a-conventional-ventricular-assist-device
#16
Pranava Sinha, Nina Deutsch, Kanishka Ratnayaka, Dingchao He, Murfad Peer, Mustafa Kurkluoglu, Mark Nuszkowski, Erin Montague, Gerald Mikesell, David Zurakowski, Richard Jonas
Mechanical assistance of systemic single ventricle is effective in pulling blood through a cavopulmonary circuit. In patients with superior cavopulmonary connection, this strategy can lead to arterial desaturation secondary to increased inferior caval flow. We hypothesized that overall augmentation in cardiac output with mechanical assistance compensates for the drop in oxygen saturation thereby maintaining tissue oxygen delivery (DO2). Bidirectional Glenn (BDG) was established in seven swine (25 kg) after a common atrium had been established by balloon septostomy...
June 15, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28659714/celltrans-an-r-package-to-quantify-stochastic-cell-state-transitions
#17
Thomas Buder, Andreas Deutsch, Michael Seifert, Anja Voss-Böhme
Many normal and cancerous cell lines exhibit a stable composition of cells in distinct states which can, e.g., be defined on the basis of cell surface markers. There is evidence that such an equilibrium is associated with stochastic transitions between distinct states. Quantifying these transitions has the potential to better understand cell lineage compositions. We introduce CellTrans, an R package to quantify stochastic cell state transitions from cell state proportion data from fluorescence-activated cell sorting and flow cytometry experiments...
2017: Bioinformatics and Biology Insights
https://www.readbyqxmd.com/read/28657206/projections-of-climate-driven-changes-in-tuna-vertical-habitat-based-on-species-specific-differences-in-blood-oxygen-affinity
#18
K A S Mislan, Curtis A Deutsch, Richard W Brill, John P Dunne, Jorge L Sarmiento
Oxygen concentrations are hypothesized to decrease in many areas of the ocean as a result of anthropogenically-driven climate change, resulting in habitat compression for pelagic animals. The oxygen partial pressure, pO2 , at which blood is 50% saturated (P50 ) is a measure of blood oxygen affinity and a gauge of the tolerance of animals for low ambient oxygen. Tuna species display a wide range of blood oxygen affinities (i.e., P50 values) and therefore may be differentially impacted by habitat compression as they make extensive vertical movements to forage on sub-daily time scales...
June 28, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28655976/iron-deficiency-anemia-in-chronic-liver-disease-etiopathogenesis-diagnosis-and-treatment
#19
REVIEW
Eleana Gkamprela, Melanie Deutsch, Dimitrios Pectasides
Chronic liver disease is accompanied by multiple hematological abnormalities. Iron deficiency anemia is a frequent complication of advanced liver disease. The etiology is multifactorial, mostly due to chronic hemorrhage into the gastrointestinal tract. The diagnosis of iron deficiency anemia is very challenging, as simple laboratory methods, including serum iron, ferritin, transferrin saturation (Tsat), and mean corpuscular volume are affected by the liver disease itself or the cause of the disease, resulting in difficulty in the interpretation of the results...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28654475/virtual-reality-and-serious-games-in-neurorehabilitation-of-children-and-adults-prevention-plasticity-and-participation
#20
Judith E Deutsch, Sarah Westcott McCoy
Use of virtual reality (VR) and serious games (SGs) interventions within rehabilitation as motivating tools for task specific training for individuals with neurological conditions are fast-developing. Within this perspective paper we use the framework of the IV STEP conference to summarize the literature on VR and SG for children and adults by three topics: Prevention; Outcomes: Body-Function-Structure, Activity and Participation; and Plasticity. Overall the literature in this area offers support for use of VR and SGs to improve body functions and to some extent activity domain outcomes...
July 2017: Pediatric Physical Therapy
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