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https://www.readbyqxmd.com/read/28726796/three-year-change-in-endothelin-1-and-markers-of-vascular-remodelling-in-a-bi-ethnic-south-african-cohort-the-sabpa-study
#1
C S du Plooy, C M C Mels, H W Huisman, R Kruger
South Africans are at high risk for developing cardiovascular disease. Endothelin-1 is known for its vasoconstrictive properties and its ability to contribute to vascular structural changes. In this study we investigated the association of change in endothelin-1 levels and change in markers implicated in vascular remodelling after 3 years. Serum endothelin-1 levels and markers of vascular remodelling such as carotid intima-media thickness, carotid cross-sectional wall area (CSWA) and arterial compliance were measured...
July 20, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28715978/the-role-of-efflux-pumps-in-tuberculosis-treatment-and-their-promise-as-a-target-in-drug-development-unraveling-the-black-box
#2
Lindsey H M Te Brake, Gerjo J de Knegt, Jurriaan E de Steenwinkel, Teunis J P van Dam, David M Burger, Frans G M Russel, Reinout van Crevel, Jan B Koenderink, Rob E Aarnoutse
Insight into drug transport mechanisms is highly relevant to the efficacious treatment of tuberculosis (TB). Major problems in TB treatment are related to the transport of antituberculosis (anti-TB) drugs across human and mycobacterial membranes, affecting the concentrations of these drugs systemically and locally. Firstly, transporters located in the intestines, liver, and kidneys all determine the pharmacokinetics and pharmacodynamics of anti-TB drugs, with a high risk of drug-drug interactions in the setting of concurrent use of antimycobacterial, antiretroviral, and antidiabetic agents...
July 17, 2017: Annual Review of Pharmacology and Toxicology
https://www.readbyqxmd.com/read/28700366/sex-differences-in-cannabis-use-disorder-diagnosis-involved-hospitalizations-in-the-united-states
#3
He Zhu, Li-Tzy Wu
OBJECTIVES: The study examined sex differences in trend and clinical characteristics of cannabis use disorder (CUD) diagnosis involved hospitalizations among adult patients. METHODS: We analyzed hospitalization data from the 2007-2011 Nationwide Inpatient Samples for patients aged 18-64 years (N = 15,114,930). Descriptive statistics were used to characterize demographic variables and to compare the proportions of CUD diagnosis and comorbid patterns between male and female hospitalizations...
July 11, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28685046/comprehensive-review-of-the-evidence-regarding-the-effectiveness-of-community-based-primary-health-care-in-improving-maternal-neonatal-and-child-health-8-summary-and-recommendations-of-the-expert-panel
#4
Robert E Black, Carl E Taylor, Shobha Arole, Abhay Bang, Zulfiqar A Bhutta, A Mushtaque R Chowdhury, Betty R Kirkwood, Nazo Kureshy, Claudio F Lanata, James F Phillips, Mary Taylor, Cesar G Victora, Zonghan Zhu, Henry B Perry
BACKGROUND: The contributions that community-based primary health care (CBPHC) and engaging with communities as valued partners can make to the improvement of maternal, neonatal and child health (MNCH) is not widely appreciated. This unfortunate reality is one of the reasons why so few priority countries failed to achieve the health-related Millennium Development Goals by 2015. This article provides a summary of a series of articles about the effectiveness of CBPHC in improving MNCH and offers recommendations from an Expert Panel for strengthening CBPHC that were formulated in 2008 and have been updated on the basis of more recent evidence...
June 2017: Journal of Global Health
https://www.readbyqxmd.com/read/28641316/a-cancer-geography-paradox-poorer-cancer-outcomes-with-longer-travelling-times-to-healthcare-facilities-despite-prompter-diagnosis-and-treatment-a-data-linkage-study
#5
Melanie Turner, Shona Fielding, Yuhan Ong, Chris Dibben, Zhiqianq Feng, David H Brewster, Corri Black, Amanda Lee, Peter Murchie
BACKGROUND: Rurality and distance from cancer treatment centres have been shown to negatively impact cancer outcomes, but the mechanisms remain obscure. METHODS: We analysed the impact of travel time to key healthcare facilities and mainland/island residency on the cancer diagnostic pathway (treatment within 62 days of referral, and within 31 days of diagnosis) and 1-year mortality using a data-linkage study with 12 339 patients. RESULTS: After controlling for important confounders, mainland patients with more than 60 min of travelling time to their cancer treatment centre ((OR 1...
June 22, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28632079/-no-there-is-nothing-wrong-with-your-eyes-my-letterhead-is-indeed-crooked-an-introduction-to-the-study-of-black-and-brown-lesbian-educators
#6
Bettina L Love
To date, there is a noticeable lack of studies that focus exclusively on the pedagogical practices, teaching experiences, identity, and gender performances of Black and Brown lesbian educators (BBLE). This special issue of the Journal of Lesbian Studies aims to make the hyperinvisibility of BBLE visible and proposes to fill this scholarly gap by exploring this topic from a variety of cultural and disciplinary perspectives.
September 22, 2016: Journal of Lesbian Studies
https://www.readbyqxmd.com/read/28585662/medication-safety-what-nurses-should-know-about-black-box-warnings
#7
Laura G Leahy
"Safety first" has always been a nursing priority-just as medication education has been an essential nursing function. Approximately 79 million individuals of all ages, birth-to-death, were prescribed psychotropic medications in 2013. Nurses of all disciplines and who work in all practice settings must be aware of the potential safety concerns related to medications patients may be taking. Black Box Warnings (BBWs) are the strictest labeling requirements that the U.S. Food and Drug Administration can mandate...
June 1, 2017: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/28575058/timing-of-rehabilitation-on-length-of-stay-and-cost-in-patients-with-hip-or-knee-joint-arthroplasty-a-systematic-review-with-meta-analysis
#8
Michael Masaracchio, William J Hanney, Xinliang Liu, Morey Kolber, Kaitlin Kirker
OBJECTIVE: To investigate the role of early initiation of rehabilitation on length of stay (LOS) and cost following total hip arthroplasty, total knee arthroplasty, or unicompartmental knee arthroplasty. DATA SOURCES: Electronic databases PubMed, CINAHL, Pedro, Embase, AMED, and the Cochrane Library were searched in July 2016. Five additional trials were identified through reference list scanning. STUDY SELECTION: Eligible studies were published in English language peer-reviewed journals; included participants that had undergone total hip arthroplasty, total knee arthroplasty, or unicompartmental knee arthroplasty reported clearly defined timing of rehabilitation onset for at least two groups; and reported at least one measure of LOS or cost...
2017: PloS One
https://www.readbyqxmd.com/read/28569542/-racial-bias-in-mock-juror-decision-making-a-meta-analytic-review-of-defendant-treatment-correction-to-mitchell-et-al-2005
#9
(no author information available yet)
Reports an error in "Racial Bias in Mock Juror Decision-Making: A Meta-Analytic Review of Defendant Treatment" by Tara L. Mitchell, Ryann M. Haw, Jeffrey E. Pfeifer and Christian A. Meissner (Law and Human Behavior, 2005[Dec], Vol 29[6], 621-637). In the article, all of the numbers in Appendix A were correct, but the signs were reversed for z' in a number of studies, which are listed. Also, in Appendix B, some values were incorrect, some signs were reversed, and some values were missing. The corrected appendix is included...
June 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/28521801/why-are-some-people-more-fit-than-others-correlates-and-determinants-of-cardiorespiratory-fitness-in-adults-protocol-for-a-systematic-review
#10
Nita Perumal, Gert B M Mensink, Thomas Keil, Jonas David Finger
BACKGROUND: Cardiorespiratory fitness (CRF) is a physical condition that is now well established as a predictor of numerous adverse health outcomes, independent of physical activity levels. In order to be able to improve CRF at the population level and to develop effective interventions and public health programmes, it is important to understand why some people are more fit than others. Therefore, the primary aim of the systematic review described in this protocol is to examine individual and interpersonal factors that are correlated with or determine CRF among adults...
May 18, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28510578/neurofeedback-as-a-form-of-cognitive-rehabilitation-therapy-following-stroke-a-systematic-review
#11
Tian Renton, Alana Tibbles, Jane Topolovec-Vranic
Neurofeedback therapy (NFT) has been used within a number of populations however it has not been applied or thoroughly examined as a form of cognitive rehabilitation within a stroke population. Objectives for this systematic review included: i) identifying how NFT is utilized to treat cognitive deficits following stroke, ii) examining the strength and quality of evidence to support the use of NFT as a form of cognitive rehabilitation therapy (CRT) and iii) providing recommendations for future investigations...
2017: PloS One
https://www.readbyqxmd.com/read/28504619/standard-area-diagrams-for-aiding-severity-estimation-scientometrics-pathosystems-and-methodological-trends-in-the-last-25-years
#12
Emerson Del Ponte, Sarah Jane Pethybridge, Clive Bock, Sami Jorge Michereff, Franklin Jackson Machado, Pierri Spolti
Standard area diagrams (SADs) have long been used as a tool to aid the estimation of plant disease severity, an essential variable in phytopathometry. Formal validation of SADs was not considered prior to the early 1990s, when considerable effort began to be invested developing SADs and assessing their value for improving accuracy of estimates of disease severity in many pathosystems. Peer-reviewed literature post-1990 was identified, selected and cataloged in bibliographic software for further scrutiny and extraction of scientometric, pathosystem- and methodological-related data...
May 15, 2017: Phytopathology
https://www.readbyqxmd.com/read/28496007/association-between-tea-consumption-and-risk-of-cognitive-disorders-a-dose-response-meta-analysis-of-observational-studies
#13
Xueying Liu, Xiaoyuan Du, Guanying Han, Wenyuan Gao
BACKGROUND: The epidemiological evidence for a dose-response relationship between tea consumption and risk of cognitive disorders is sparse. The aim of the study was to summarize the evidence for the association of tea consumption with risk of cognitive disorders and assess the dose-response relationship. METHODS: We searched electronic databases of Pubmed, Embase, and Cochrane Library (from 1965 to Jan 19, 2017) for eligible studies that published in the international journals...
June 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28474775/subcortical-hyperintensities-in-the-cholinergic-system-are-associated-with-improvements-in-executive-function-in-older-adults-with-coronary-artery-disease-undergoing-cardiac-rehabilitation
#14
Calvin Santiago, Nathan Herrmann, Walter Swardfager, Mahwesh Saleem, Paul I Oh, Sandra E Black, Janelle Bradley, Krista L Lanctôt
OBJECTIVE: Coronary artery disease (CAD) is frequently accompanied by white matter hyperintensities and executive dysfunction. Because acetylcholine is important in executive function, these symptoms may be exacerbated by subcortical hyperintensities (SH) located in cholinergic (CH) tracts. This study investigated the effects of SH on cognitive changes in CAD patients undergoing a 48-week cardiac rehabilitation program. METHODS: Fifty patients (age 66.5 ± 7.1 years, 84% male) underwent the National Institute of Neurological Disorders and Stroke - Canadian Stroke Network neurocognitive battery at baseline and 48 weeks...
May 5, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28472533/a-systematic-review-of-the-impact-of-physician-implicit-racial-bias-on-clinical-decision-making
#15
Erin Dehon, Nicole Weiss, Jonathan Jones, Whitney Faulconer, Elizabeth Hinton, Sarah Sterling
OBJECTIVES: Disparities in diagnosis and treatment of racial minorities exist in the emergency department (ED). A better understanding of how physician implicit (unconscious) bias contributes to these disparities may help identify ways to eliminate such racial disparities. The objective of this systematic review was to examine and summarize the evidence on the association between physician implicit racial bias and clinical decision making. METHODS: Based on PRISMA guidelines, a structured electronic literature search of PubMed, CINAHL, Scopus, and PsycINFO databases was conducted...
May 4, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28471913/increased-fat-absorption-from-enteral-formula-through-an-in-line-digestive-cartridge-in-patients-with-cystic-fibrosis
#16
Steven Freedman, David Orenstein, Philip Black, Perry Brown, Karen McCoy, John Stevens, Danica Grujic, Russell Clayton
OBJECTIVES: Supplemental enteral nutrition (EN) is used by approximately 12% of people with cystic fibrosis (CF). The objective of this study was to evaluate the safety, tolerability, and fat absorption of a new in-line digestive cartridge (Relizorb) that hydrolyzes fat in enteral formula provided to patients with CF. METHODS: Patients with CF receiving EN participated in a multicenter, randomized, double-blind, crossover trial with an open-label safety evaluation period...
July 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28445504/correction-gastroenteritis-therapies-in-developed-countries-systematic-review-and-meta-analysis
#17
Stephen B Freedman, Dion Pasichnyk, Karen J L Black, Eleanor Fitzpatrick, Serge Gouin, Andrea Milne, Lisa Hartling
[This corrects the article DOI: 10.1371/journal.pone.0128754.].
2017: PloS One
https://www.readbyqxmd.com/read/28440921/pediatric-pulmonology-year-in-review-2016-part-1
#18
REVIEW
David J Birnkrant, Jane B Black, Ignacio E Tapia, Thomas Nicolai, William A Gower, Terry L Noah
Pediatric Pulmonology continues to publish research and clinical topics related to the entire range of children's respiratory disorders. As we have done annually in recent years, we here summarize the past year's publications in our major topic areas, as well as selected literature in these areas from other core journals relevant to our discipline. This review (Part 1) covers selected articles on sleep, diagnostic testing/endoscopy, respiratory complications of neuromuscular disorders, and rare lung diseases...
April 25, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28434476/a-qualitative-approach-exploring-the-acceptability-of-yoga-for-minorities-living-with-arthritis-where-are-the-people-who-look-like-me
#19
Kimberly R Middleton, Miriam Magaña López, Steffany Haaz Moonaz, Gladys Tataw-Ayuketah, Michael M Ward, Gwenyth R Wallen
OBJECTIVES: To examine the acceptability of yoga research tailored to recruit and retain a minority population (both English and Spanish speaking) with arthritis. Yoga research for arthritis often underrepresents minorities and acceptability for this population has not previously been investigated. DESIGN: Acceptability was evaluated using retention, adherence, journals, and semi-structured exit interviews from twelve participants with osteoarthritis or rheumatoid arthritis undergoing an 8-week yoga intervention...
April 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28399320/physical-activity-functional-ability-and-obesity-in-older-adults-a-gender-difference
#20
Kimberlee A Gretebeck, LeAnn M Sabatini, David R Black, Randall J Gretebeck
Disability, institutionalization, and loss of independence may be directly caused or exacerbated by physical inactivity and obesity. The purpose of the current cross-sectional survey was to explore the impact of gender and obesity on functional ability tasks, physical activity, and psychosocial factors in older adults. Participants comprised 964 University retirees (55% female, mean age = 75.3 years, SD = 6.7 years) with a mean body mass index (BMI) of 26.1 kg/m(2) (SD = 4.7 kg/m(2)). Results revealed significant gender and BMI interaction effects...
April 11, 2017: Journal of Gerontological Nursing
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