keyword
MENU ▼
Read by QxMD icon Read
search

Autism AND female

keyword
https://www.readbyqxmd.com/read/29777472/circumscribed-interests-and-attention-in-autism-the-role-of-biological-sex
#1
Clare Harrop, Desiree Jones, Shuting Zheng, Sallie Nowell, Brian A Boyd, Noah Sasson
Recent studies suggest that circumscribed interests (CI) in females with Autism Spectrum Disorder (ASD) may align more closely with interests reported in typical female development than those typically reported for ASD males. We used eye-tracking to quantify attention to arrays containing combinations of male, female and neutral images in elementary-aged males and females with and without ASD. A number of condition × sex effects emerged, with both groups attending to images that corresponded with interests typically associated with their biological sex...
May 18, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29772261/maternal-immune-activation-with-staphylococcal-enterotoxin-a-produces-unique-behavioral-changes-in-c57bl-6-mouse-offspring
#2
Ruthy Glass, Sara Norton, Nicholas Fox, Alexander W Kusnecov
Stimulation of the immune system during pregnancy, known as maternal immune activation (MIA), can cause long-lasting neurobiological and behavioral changes in the offspring. This phenomenon has been implicated in the etiology of developmental psychiatric disorders, such as autism and schizophrenia. Much of this evidence is predicated on animal models using bacterial agents such as LPS and/or viral mimics such as Poly I:C, both of which act through toll-like receptors. However, fewer studies have examined the role of direct activation of maternal T-cells during pregnancy using microbial agents...
May 14, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29762671/motor-impairments-correlate-with-social-deficits-and-restricted-neuronal-loss-in-an-environmental-model-of-autism
#3
Tareq Al Sagheer, Obelia Haida, Anais Balbous, Maureen Francheteau, Emmanuel Matas, Pierre-Olivier Fernagut, Mohamed Jaber
Background: Motor impairments are amongst the earliest and most consistent signs of autism spectrum disorders (ASD) but are not used as diagnostic criteria. In addition, the relationship between motor and cognitive impairments and their respective neural substrates remain unknown. Methods: Here, we aimed at determining whether a well-acknowledged animal model of ASD, the valproic acid (VPA) model, displays motor impairments and whether they may correlate with social deficits and neuronal loss within motor brain areas...
May 12, 2018: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29758565/clinical-and-genetic-analysis-of-a-rare-syndrome-associated-with-neoteny
#4
Richard F Walker, Serban Ciotlos, Qing Mao, Robert Chin, Snezana Drmanac, Nina Barua, Misha R Agarwal, Rebecca Yu Zhang, Zhenyu Li, Michelle Ka Yan Wu, Kevin Sun, Katharine Lee, Staci Nguyen, Jia Sophie Liu, Paolo Carnevali, Radoje Drmanac, Brock A Peters
PurposeWe describe a novel syndrome in seven female patients with extreme developmental delay and neoteny.MethodsAll patients in this study were female, aged 4 to 23 years, were well below the fifth percentile in height and weight, had failed to develop sexually, and lacked the use of language. Karyotype and array chromosome genomic hybridization analysis failed to identify large-scale structural variations. To further understand the underlying cause of disease in these patients, whole-genome sequencing was performed...
April 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29752658/cytoplasmic-fmrp-interacting-protein-1-2-cyfip1-2-expression-analysis-in-autism
#5
Rezvan Noroozi, Mir Davood Omrani, Arezou Sayad, Mohammad Taheri, Soudeh Ghafouri-Fard
Cytoplasmic FMRP interacting proteins 1 and 2 (CYFIP1/2) have been previously shown to be associated with central nervous system (CNS) disorders such as autism spectrum disorder (ASD). Moreover, dysregulation of their expression levels results in disturbances in CNS maturation and neuronal interconnections. In the present study, we compared expression levels of CYFIP1/2 in peripheral blood of 30 ASD patients and 41 healthy subjects by means of real time PCR. Expression analysis showed significant over-expression of CYFIP1/2 in ASD patients compared with healthy subjects (Fold change = 3...
May 11, 2018: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29752629/brief-report-gender-and-age-of-diagnosis-time-trends-in-children-with-autism-using-australian-medicare-data
#6
Tamara May, Katrina Williams
Recent evidence suggests the male predominance in Autism Spectrum Disorder (ASD) may be decreasing. Secondary analyses of Australian Medicare data (paediatrician/child psychiatrist items for diagnosing ASD before age 13) were used (N = 73,463 unique children from 1-July-2008 to 30-June-2016). Cumulative incidence of ASD in 4-year-olds in 2015/2016 was 1.10% [95% CI 1.06-1.14], males 1.66% [95% CI 1.60-1.72] and females 0.51% [95% CI 0.47-0.55]. New diagnoses significantly increased in older (5-12 years) males and females but not younger (0-4 years) children, from 2010/2011 to 2015/2016...
May 11, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29748736/long-term-social-skills-group-training-for-children-and-adolescents-with-autism-spectrum-disorder-a-randomized-controlled-trial
#7
Ulf Jonsson, Nora Choque Olsson, Christina Coco, Anders Görling, Oskar Flygare, Anna Råde, Qi Chen, Steve Berggren, Kristiina Tammimies, Sven Bölte
Social skills group training (SSGT) is widely used for intellectually able children and adolescents with autism spectrum disorder (ASD). Previous studies indicate small to moderate effects on social communication capacities. The duration of most available programs is relatively short, and extended training might lead to further improvement. This randomized controlled trial compared an extended 24-week version of the SSGT program KONTAKT with standard care. The weekly sessions gradually shifted in content from acquisition of new skills to real-world application of the acquired skills...
May 10, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29741976/self-reported-autism-spectrum-disorder-symptoms-among-adults-referred-to-a-gender-identity-clinic
#8
Lieke E W Vermaat, Anna I R van der Miesen, Annelou L C de Vries, Thomas D Steensma, Arne Popma, Peggy T Cohen-Kettenis, Baudewijntje P C Kreukels
PURPOSE: The purpose of this study was to (1) investigate autism spectrum disorder (ASD) symptoms in a sample of adults referred for gender dysphoria (GD) compared to typically developing (TD) populations, (2) see whether males assigned at birth with GD (MaBGD s) and females assigned at birth with GD (FaBGD s) differ in ASD symptom levels, (3) study the role of sexual orientation, and (4) investigate ASD symptoms' correlation with GD symptoms. METHODS: The Autism-Spectrum Quotient (AQ) was used to measure ASD symptoms, and the Utrecht Gender Dysphoria Scale (UGDS) was used to measure the intensity of GD...
May 9, 2018: LGBT Health
https://www.readbyqxmd.com/read/29736809/prevalence-of-the-wish-to-be-of-the-opposite-gender-in-adolescents-and-adults-with-autism-spectrum-disorder
#9
Anna I R van der Miesen, Hannah Hurley, Anneloes M Bal, Annelou L C de Vries
Several studies have suggested an overrepresentation of (symptoms of) autism spectrum disorder (ASD) among individuals with gender dysphoria. Three studies have taken the inverse approach in children with ASD and showed increased parent report of the wish to be of the opposite gender in this group. This study compared the self-reported wish to be of the opposite gender (one item of the Youth Self-Report [YSR] and the Adult Self-Report [ASR]) of 573 adolescents (469 assigned boys and 104 assigned girls) and 807 adults (616 assigned males and 191 assigned females) with ASD to 1016 adolescents and 846 adults from the general population...
May 7, 2018: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/29734506/predictors-of-quality-of-life-for-autistic-adults
#10
David Mason, Helen McConachie, Deborah Garland, Alex Petrou, Jacqui Rodgers, Jeremy R Parr
Research with adults on the autism spectrum is as yet limited in scope and quality. The present study describes quality of life (QoL) of a large sample of autistic adults in the UK and investigates characteristics that may be predictive of QoL. A total of 370 autistic adults from the Adult Autism Spectrum Cohort-UK (ASC-UK) completed the WHOQoL-BREF, and the Social Responsiveness Scale (SRS, autism symptom severity), along with the ASC-UK registration questionnaire giving information on mental health and their life situation...
May 7, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29730431/mayer-rokitansky-kuster-hauser-syndrome-and-16p11-2-recurrent-microdeletion-a-case-report-and-review-of-the-literature
#11
Marta Gatti, Gianluca Tolva, Silvia Bergamaschi, Claudia Giavoli, Susanna Esposito, Paola Marchisio, Donatella Milani
BACKGROUND: Mayer-Rokitansky-Kuster-Hauser syndrome (OMIM #277000) is a rare disorder of the female reproductive tract. Its etiology is still unknown for the majority of patients, even if the genetic background of this condition has been intensively studied. Chromosome 16p11.2 deletion syndrome (OMIM # 611913) is a well-known recurrent deletion syndrome that can present with various clinical phenotypes, including developmental delay, intellectual disability, autism spectrum disorder, obesity, and an increased frequency of congenital defects...
May 3, 2018: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29729302/neonatal-immune-activation-by-lipopolysaccharide-causes-inadequate-emotional-responses-to-novel-situations-but-no-changes-in-anxiety-or-cognitive-behavior-in-wistar-rats
#12
Iveta Vojtechova, Tomas Petrasek, Kristyna Maleninska, Hana Brozka, Hana Tejkalova, Jiri Horacek, Ales Stuchlik, Karel Vales
Infection during the prenatal or neonatal stages of life is considered one of the major risk factors for the development of mental diseases such as schizophrenia or autism. However, the impacts of such an immune challenge on adult behavior are still not clear. In our study, we used a model of early postnatal immune activation by the application of bacterial endotoxin lipopolysaccharide (LPS) to rat pups at a dose of 2 mg/kg from postnatal day (PD) 5 to PD 9. In adulthood, the rats were tested in a battery of tasks probing various aspects of behavior: spontaneous activity (open field test), social behavior (social interactions and female bedding exploration), anxiety (elevated plus maze), cognition (active place avoidance in Carousel) and emotional response (ultrasonic vocalization recording)...
May 2, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29717186/novel-nexmif-pathogenic-variant-in-a-boy-with-severe-autistic-features-intellectual-disability-and-epilepsy-and-his-mildly-affected-mother
#13
Nelle Lambert, Corinne Dauve, Emmanuelle Ranza, Periklis Makrythanasis, Federico Santoni, Frédérique Sloan-Béna, Stefania Gimelli, Jean-Louis Blouin, Michel Guipponi, Armand Bottani, Stylianos E Antonarakis, Markus M Kosel, Joel Fluss, Ariane Paoloni-Giacobino
Intellectual disability (ID) and autism spectrum disorders are complex neurodevelopmental disorders occurring among all ethnic and socioeconomic groups. Pathogenic variants in the neurite extension and migration factor (NEXMIF) gene (formerly named KIAA2022) on the X chromosome are responsible for ID, autistic behavior, epilepsy, or dysmorphic features in males. Most affected females described had a milder phenotype or were asymptomatic obligate carriers. We report here for the first time mother-to-son transmission of a novel NEXMIF truncating variant without X-inactivation skewing in the blood...
May 1, 2018: Journal of Human Genetics
https://www.readbyqxmd.com/read/29713261/transcranial-direct-current-stimulation-tdcs-can-modulate-eeg-complexity-of-children-with-autism-spectrum-disorder
#14
Jiannan Kang, Erjuan Cai, Junxia Han, Zhen Tong, Xin Li, Estate M Sokhadze, Manuel F Casanova, Gaoxiang Ouyang, Xiaoli Li
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder which affects the developmental trajectory in several behavioral domains, including impairments of social communication, cognitive and language abilities. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique, and it was used for modulating the brain disorders. In this paper, we enrolled 13 ASD children (11 males and 2 females; mean ± SD age: 6.5 ± 1.7 years) to participate in our trial. Each patient received 10 treatments over the dorsolateral prefrontal cortex (DLPFC) once every 2 days...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29705922/gender-identity-in-autism-sex-differences-in-social-affiliation-with-gender-groups
#15
Kate Cooper, Laura G E Smith, Ailsa J Russell
High rates of gender variance have been reported in autistic people, with higher variance in autistic females than males. The social component of gender identity may be affected, with autistic females experiencing lower identification with and feeling less positively about their gender groups than controls. We measured gender identification, gender self-esteem, and aspects of gender expression (masculinity and femininity) in autistic natal males and females, and controls (N = 486). We found that autistic people had lower gender identification and gender self-esteem than controls, and autistic natal females had lower gender identification than autistic natal males and natal female controls...
April 28, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29704141/2d-4d-ratio-in-neurodevelopmental-disorders-a-twin-study
#16
Lynnea Myers, Annelies Van't Westeinde, Ralf Kuja-Halkola, Kristiina Tammimies, Sven Bölte
The second to fourth digit (2D:4D) ratio is of interest in autism spectrum disorder (ASD). Studies on the relationship of this ratio with other neurodevelopmental disorders (NDDs) are lacking. Investigating the association between the ratio and NDDs in twins can provide insight into genetic and/or environmental factors driving the ratio. Hand images were collected in N = 238 twins with NDDs or typical development from 70 monozygotic and 49 dizygotic pairs to examine ratios and their associations to DSM-5 defined categorical NDDs, autistic traits, zygosity, and sex...
April 27, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29702302/cluster-analysis-reveals-subclinical-subgroups-with-shared-autistic-and-schizotypal-traits
#17
Talitha C Ford, Pragalathan Apputhurai, Denny Meyer, David P Crewther
Autism and schizophrenia spectrum research is typically based on coarse diagnostic classification, which overlooks individual variation within clinical groups. This method limits the identification of underlying cognitive, genetic and neural correlates of specific symptom dimensions. This study, therefore, aimed to identify homogenous subclinical subgroups of specific autistic and schizotypal traits dimensions, that may be utilised to establish more effective diagnostic and treatment practices. Latent profile analysis of subscale scores derived from an autism-schizotypy questionnaire, completed by 1678 subclinical adults aged 18-40 years (1250 females), identified a local optimum of eight population clusters: High, Moderate and Low Psychosocial Difficulties; High, Moderate and Low Autism-Schizotypy; High Psychosis-Proneness; and Moderate Schizotypy...
April 14, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29701730/prevalence-of-autism-spectrum-disorder-among-children-aged-8-years-autism-and-developmental-disabilities-monitoring-network-11-sites-united-states-2014
#18
Jon Baio, Lisa Wiggins, Deborah L Christensen, Matthew J Maenner, Julie Daniels, Zachary Warren, Margaret Kurzius-Spencer, Walter Zahorodny, Cordelia Robinson Rosenberg, Tiffany White, Maureen S Durkin, Pamela Imm, Loizos Nikolaou, Marshalyn Yeargin-Allsopp, Li-Ching Lee, Rebecca Harrington, Maya Lopez, Robert T Fitzgerald, Amy Hewitt, Sydney Pettygrove, John N Constantino, Alison Vehorn, Josephine Shenouda, Jennifer Hall-Lande, Kim Van Naarden Braun, Nicole F Dowling
PROBLEM/CONDITION: Autism spectrum disorder (ASD). PERIOD COVERED: 2014. DESCRIPTION OF SYSTEM: The Autism and Developmental Disabilities Monitoring (ADDM) Network is an active surveillance system that provides estimates of the prevalence of autism spectrum disorder (ASD) among children aged 8 years whose parents or guardians reside within 11 ADDM sites in the United States (Arizona, Arkansas, Colorado, Georgia, Maryland, Minnesota, Missouri, New Jersey, North Carolina, Tennessee, and Wisconsin)...
April 27, 2018: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29698806/identification-of-two-14q32-deletions-involving-dicer1-associated-with-the-development-of-dicer1-related-tumors
#19
John C Herriges, Sara Brown, Maria Longhurst, Jillian Ozmore, John B Moeschler, Aura Janze, Jeanne Meck, Sarah T South, Erica F Andersen
DICER1 encodes an RNase III endonuclease protein that regulates the production of small non-coding RNAs. Germline mutations in DICER1 are associated with an autosomal dominant hereditary cancer predisposition syndrome that confers an increased risk for the development of several rare childhood and adult-onset tumors, the most frequent of which include pleuropulmonary blastoma, ovarian sex cord-stromal tumors, cystic nephroma, and thyroid gland neoplasia. The majority of reported germline DICER1 mutations are truncating sequence-level alterations, suggesting that a loss-of-function type mechanism drives tumor formation in DICER1 syndrome...
April 23, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29698114/cleft-care-of-internationally-adopted-children-from-china
#20
Alison Kaye, Columbine Che, William L Chew, Elizabeth A Stueve, Shao Jiang
OBJECTIVE: To quantify a population of international adoptees from China with cleft lip and/or palate to assess presentations and team management practices. DESIGN: Single institution retrospective. PATIENTS: One hundred one patients with cleft lip and/or palate and history of international adoption from China. RESULTS: Forty-nine males and 52 females were adopted from 2001 to 2014. Median age at arrival was 26 months...
January 1, 2018: Cleft Palate-craniofacial Journal
keyword
keyword
45491
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"