keyword
https://read.qxmd.com/read/38391830/fatigue-among-greek-parents-of-children-with-autistic-spectrum-disorder-the-roles-of-spirituality-and-social-support
#21
JOURNAL ARTICLE
Eugenia Halki, Maria Kapiri, Sotirios Plakas, Chrysoula Tsiou, Ourania Govina, Petros Galanis, Victoria Alikari
The high demands of caring for and raising a child with autism spectrum disorder on a daily basis may lead parents to physical and mental fatigue. This study aimed to assess the effect of social support and spirituality on the fatigue of parents with children with autistic spectrum disorder. A cross-sectional study with a convenience sample was conducted in Schools of Special Education in Attica (Greece). The sample consisted of 123 parents who completed The Fatigue Assessment Scale (FAS), the Multidimensional Scale of Perceived Social Support (MSPSS), and the Functional Assessment of Chronic Illness Therapy Spiritual Well-Being Scale (FACIT Sp-12) to measure the levels of fatigue, social support, and spirituality, respectively...
February 10, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38390906/long-term-effects-of-neuraxial-analgesia
#22
JOURNAL ARTICLE
Rachel J Kearns, Malcolm A Broom, Dominique N Lucas
PURPOSE OF REVIEW: This review article explores the potential longer-term implications of neuraxial analgesia in labour for both the mother and her child. RECENT FINDINGS: Neuraxial techniques for labour analgesia are well tolerated and effective, and long-term adverse sequelae are rare. Labour epidural analgesia is not independently associated with long-term headache, backache, postnatal depression or anal sphincter injury, and evidence supports that epidurals may offer protection against severe maternal morbidity, particularly in women at a higher risk of complications...
February 22, 2024: Current Opinion in Anaesthesiology
https://read.qxmd.com/read/38356022/the-effect-of-family-characteristics-on-the-functioning-of-a-child-with-an-autistic-spectrum-disorder-in-bedouin-society-in-israel
#23
JOURNAL ARTICLE
Hagar Binoun Chaki, Yifat Faran
Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by difficulties in communication and social-emotional interaction. It is associated with an increase of parental stress and poor family functioning, both of which are harmful for a child's functioning and adaptive behavior. An important source of support to parents are grandparents, especially in traditional populations. One such population is the Bedouin population. The present study tested the association between emotional support from mother and mother-in-law to the adaptive behavior of children with ASD, and whether this relation is serially mediated by family functioning and satisfaction in life as reported by Bedouin mothers of children with ASD...
February 15, 2024: Journal of Autism and Developmental Disorders
https://read.qxmd.com/read/38352135/the-science-of-uncertainty-guides-fetal-neonatal-neurology-principles-and-practice-diagnostic-prognostic-opportunities-and-challenges
#24
REVIEW
Mark Steven Scher
Fetal-neonatal neurologists (FNNs) consider diagnostic, therapeutic, and prognostic decisions strengthened by interdisciplinary collaborations. Bio-social perspectives of the woman's health influence evaluations of maternal-placental-fetal (MPF) triad, neonate, and child. A dual cognitive process integrates "fast thinking-slow thinking" to reach shared decisions that minimize bias and maintain trust. Assessing the science of uncertainty with uncertainties in science improves diagnostic choices across the developmental-aging continuum...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38350623/-autism-and-camouflage
#25
JOURNAL ARTICLE
Victor Ruggieri
Autism is a neurobiologically based neurodevelopmental disorder with high prevalence and a clear predominance in males. It is characterized by deficits in social cognition and communication, restricted interests, and stereotyped behaviors, frequently associated with sensory dysfunction others neurodevelopmental conditions, neuropsychiatric disorders, epilepsy, and/or sleep disorders. This condition will accompany people throughout their lives, which will generate various support and treatment needs. People with autism often need to "fit in" and for this they use techniques such as camouflage, also called masking...
March 2024: Medicina
https://read.qxmd.com/read/38311602/what-are-the-autism-research-priorities-of-autistic-adults-in-scotland
#26
JOURNAL ARTICLE
Eilidh Cage, Catherine J Crompton, Sarah Dantas, Khiah Strachan, Rachel Birch, Mark Robinson, Stasa Morgan-Appel, Charlie MacKenzie-Nash, Aaron Gallagher, Monique Botha
Although research has the potential to improve autistic people's lives, lots of funding goes towards research looking at topics which autistic people say has little impact in their everyday lives. Autistic people's lives can be different depending on where they live, and Scotland is a unique country in many ways. We wanted to find out which topics autistic people in Scotland want to see research on. Our team of autistic and non-autistic researchers (including university-based and community researchers) created a survey where 225 autistic adults rated and ranked the importance of possible research topics and shared their thoughts on what topics mattered to them...
February 4, 2024: Autism: the International Journal of Research and Practice
https://read.qxmd.com/read/38282331/contribution-of-socio-demographic-and-clinical-characteristics-to-predict-initial-referrals-to-psychosocial-interventions-in-patients-with-serious-mental-illness
#27
JOURNAL ARTICLE
Guillaume Barbalat, Julien Plasse, Isabelle Chéreau-Boudet, Benjamin Gouache, Emilie Legros-Lafarge, Catherine Massoubre, Nathalie Guillard-Bouhet, Frédéric Haesebaert, Nicolas Franck
AIMS: Psychosocial rehabilitation (PSR) is at the core of psychiatric recovery. There is a paucity of evidence regarding how the needs and characteristics of patients guide clinical decisions to refer to PSR interventions. Here, we used explainable machine learning methods to determine how socio-demographic and clinical characteristics contribute to initial referrals to PSR interventions in patients with serious mental illness. METHODS: Data were extracted from the French network of rehabilitation centres, REHABase, collected between years 2016 and 2022 and analysed between February and September 2022...
January 29, 2024: Epidemiology and Psychiatric Sciences
https://read.qxmd.com/read/38281274/the-association-between-threatened-miscarriage-and-autism-spectrum-disorder-and-attention-deficit-hyperactivity-disorder-in-offspring-by-age-14-years
#28
JOURNAL ARTICLE
Daire Buckley, Ali S Khashan, Fergus P McCarthy, Karen O'Connor, Gillian M Maher
OBJECTIVE: To examine the association between threatened miscarriage, and neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in offspring by age 14 years. METHODS: We used data from the Millennium Cohort Study, a nationally representative longitudinal study of children born in the UK. Data on threatened miscarriage and potential confounders were maternal-reported and collected at 9 months postpartum...
January 28, 2024: Journal of Autism and Developmental Disorders
https://read.qxmd.com/read/38280915/short-term-neonatal-and-long-term-neurodevelopmental-outcome-of-children-born-term-low-birth-weight
#29
JOURNAL ARTICLE
Ho Yeon Kim, Geum Joon Cho, Ki Hoon Ahn, Soon-Cheol Hong, Min-Jeong Oh, Hai-Joong Kim
This study aimed to examine the impact of term LBW on short-term neonatal and long-term neurodevelopmental outcomes in children 5-7 years of age. This is a population-based cohort study that merged national data from the Korea National Health Insurance claims and National Health Screening Program for Infants and Children. The participants were women who gave birth at a gestational age of ≥ 37 weeks between 2013 and 2015 in the Republic of Korea, and were tracked during 2020 for the neurodevelopmental surveillance of their children...
January 27, 2024: Scientific Reports
https://read.qxmd.com/read/38261317/maternal-autistic-traits-and-adverse-birth-outcomes
#30
JOURNAL ARTICLE
Mariko Hosozawa, Noriko Cable, Satoyo Ikehara, Yuri Aochi, Kanami Tanigawa, Sachiko Baba, Kumi Hirokawa, Tadashi Kimura, Tomotaka Sobue, Hiroyasu Iso
IMPORTANCE: Women with a high level of autistic traits in the general population may experience larger health disparities during pregnancy, particularly women diagnosed with autism spectrum disorder (ASD), which in turn may be associated with increased risk of adverse birth outcomes. OBJECTIVE: To investigate the association between maternal autistic traits and the risk of adverse birth outcomes in the general population. DESIGN, SETTING, AND PARTICIPANTS: This cohort study included mothers of singletons from a nationwide, multicenter prospective birth cohort, the Japan Environmental Children's Study...
January 2, 2024: JAMA Network Open
https://read.qxmd.com/read/38260618/rapid-effects-of-valproic-acid-on-the-fetal-brain-transcriptome-implications-for-brain-development-and-autism
#31
Bruce Krueger, Susan Dorsey, Evelina Mocci, Malcolm Lane
There is an increased incidence of autism among the children of women who take the anti-epileptic, mood-stabilizing drug, valproic acid (VPA) during pregnancy; moreover, exposure to VPA in utero causes autistic-like symptoms in rodents and non-human primates. Analysis of RNA-seq data obtained from E12.5 fetal mouse brains 3 hours after VPA administration to the pregnant dam revealed that VPA rapidly and significantly increased or decreased the expression of approximately 7,300 genes. No significant sex differences in VPA-induced gene expression were observed...
January 10, 2024: Research Square
https://read.qxmd.com/read/38248252/may-female-autism-spectrum-be-masked-by-eating-disorders-borderline-personality-disorder-or-complex-ptsd-symptoms-a-case-series
#32
Barbara Carpita, Benedetta Nardi, Cristiana Pronestì, Francesca Parri, Federico Giovannoni, Ivan Mirko Cremone, Stefano Pini, Liliana Dell'Osso
Introduction: The prevalence of Autism Spectrum Disorder (ASD) is four times higher in males than females; however, females are significantly more likely to go undiagnosed due to the existence of a "female autistic phenotype", a manifestation unique to females that conflicts with conventional, masculine conceptualizations of ASD. Furthermore, subthreshold autistic traits, which exert a significantly negative impact on quality of life and represent a vulnerability factor for the development of other psychopathological conditions, may remain even more under-recognized...
December 30, 2023: Brain Sciences
https://read.qxmd.com/read/38243409/employment-profiles-of-autistic-people-an-8-year-longitudinal-study
#33
JOURNAL ARTICLE
Simon M Bury, Darren Hedley, Mirko Uljarević, Xia Li, Mark A Stokes, Sander Begeer
Autistic adults experience difficulties finding and keeping employment. However, research investigating reasons that might explain this difficulty produce mixed results. We gave a survey to 2449 autistic adults and used a statistic method to group them based on their employment status over 8 years. We identified four employment groups that best captured the experiences of autistic adults; this included a group that experienced stable unemployment, a group that experienced stable employment, a group that had high employment that reduced over time, and a group whose employment increased over the 8 years...
January 19, 2024: Autism: the International Journal of Research and Practice
https://read.qxmd.com/read/38225364/navigating-adolescence-pubertal-development-in-autism-spectrum-conditions-and-its-relation-to-mental-health
#34
JOURNAL ARTICLE
Annabeth P Groenman, Saskia van der Oord, Hilde M Geurts
Adolescence is a period of social, psychological, and physiological change, including the onset of puberty. Differential pubertal onset has been linked to a myriad of problems, including mental health problems. Therefore, we aim to investigate deviating pubertal development in autism, and whether this is more pronounced in girls than in boys. A total of 68 individuals (nASC  = 34, nCOM (comparisons) = 34) aged 12 to 16 years were administered test concerning pubertal development and mental health (i...
January 16, 2024: Archives of Women's Mental Health
https://read.qxmd.com/read/38221678/women-s-attitudes-towards-disclosure-of-genetic-information-in-pregnancy-with-varying-levels-of-penetrance
#35
JOURNAL ARTICLE
Vitalia Libman, Michal Macarov, Yechiel Friedlander, Drorith Hochner-Celnikier, Yishai Sompolinsky, Uri P Dior, Michael Osovsky, Lina Basel-Salmon, Arnon Wiznitzer, Yehuda Neumark, Vardiella Meiner, Ayala Frumkin, Hagit Hochner, Shiri Shkedi-Rafid
BACKGROUND: Chromosomal-microarray-analysis (CMA) may reveal susceptibility-loci (SL) of varied penetrance for autism-spectrum-disorder (ASD) and other neurodevelopmental conditions. Attitudes of women/parents to disclosure of SL during pregnancy are understudied. METHODS: A multiple-choice questionnaire was distributed to postpartum women. Data were collected on women's interest to receive prenatal genetic information with various levels of penetrance. RESULTS: Women's (n = 941) disclosure choices were dependent on the magnitude of risk: approximately 70% supported disclosure of either full or 40% penetrance, 53% supported disclosure at a 20% risk threshold, and 40% supported disclosure at 10% or less...
January 14, 2024: Prenatal Diagnosis
https://read.qxmd.com/read/38199043/cord-blood-lipid-correlation-network-profiles-are-associated-with-subsequent-attention-deficit-hyperactivity-disorder-and-autism-spectrum-disorder-symptoms-at-2-years-a-prospective-birth-cohort-study
#36
JOURNAL ARTICLE
Kristina Vacy, Sarah Thomson, Archer Moore, Alex Eisner, Sam Tanner, Cindy Pham, Richard Saffrey, Toby Mansell, David Burgner, Fiona Collier, Peter Vuillermin, Martin O'Hely, Wah Chin Boon, Peter Meikle, Satvika Burugupalli, Anne-Louise Ponsonby
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are neurodevelopmental conditions with early life origins. Alterations in blood lipids have been linked to ADHD and ASD; however, prospective early life data are limited. This study examined (i) associations between the cord blood lipidome and ADHD/ASD symptoms at 2 years of age, (ii) associations between prenatal and perinatal predictors of ADHD/ASD symptoms and cord blood lipidome, and (iii) mediation by the cord blood lipidome...
January 9, 2024: EBioMedicine
https://read.qxmd.com/read/38198049/prenatal-exposure-to-covid-19-mrna-vaccine-bnt162b2-induces-autism-like-behaviors-in-male-neonatal-rats-insights-into-wnt-and-bdnf-signaling-perturbations
#37
JOURNAL ARTICLE
Mumin Alper Erdogan, Orkun Gurbuz, Mehmet Fatih Bozkurt, Oytun Erbas
The COVID-19 pandemic catalyzed the swift development and distribution of mRNA vaccines, including BNT162b2, to address the disease. Concerns have arisen about the potential neurodevelopmental implications of these vaccines, especially in susceptible groups such as pregnant women and their offspring. This study aimed to investigate the gene expression of WNT, brain-derived neurotrophic factor (BDNF) levels, specific cytokines, m-TOR expression, neuropathology, and autism-related neurobehavioral outcomes in a rat model...
April 2024: Neurochemical Research
https://read.qxmd.com/read/38188276/estimating-life-expectancy-and-years-of-life-lost-for-autistic-people-in-the-uk-a-matched-cohort-study
#38
JOURNAL ARTICLE
Elizabeth O'Nions, Dan Lewer, Irene Petersen, Jude Brown, Joshua E J Buckman, Rebecca Charlton, Claudia Cooper, CÉline El Baou, Francesca Happé, Jill Manthorpe, Douglas G J McKechnie, Marcus Richards, Rob Saunders, Cathy Zanker, Will Mandy, Joshua Stott
BACKGROUND: Previous research has shown that people who have been diagnosed autistic are more likely to die prematurely than the general population. However, statistics on premature mortality in autistic people have often been misinterpreted. In this study we aimed to estimate the life expectancy and years of life lost experienced by autistic people living in the UK. METHODS: We studied people in the IQVIA Medical Research Database with an autism diagnosis between January 1, 1989 and January 16, 2019...
January 2024: The Lancet regional health. Europe
https://read.qxmd.com/read/38178255/the-association-between-social-camouflage-and-mental-health-among-autistic-people-in-japan-and-the-uk-a-cross-cultural-study
#39
JOURNAL ARTICLE
Fumiyo Oshima, Toru Takahashi, Masaki Tamura, Siqing Guan, Mikuko Seto, Laura Hull, William Mandy, Kenji Tsuchiya, Eiji Shimizu
BACKGROUND: To examine the relationship between social camouflage and mental health in Japanese autistic adults and make an international comparison with a sample from the UK. METHODS: This study analysed secondary data of participants with a self-reported diagnosis of autism from Japan (N = 210; 123 men and 87 women) and the UK (N = 305; 181 women, 104, men, and 18 nonbinary). The relationships between the quadratic term of the Camouflaging Autistic Traits Questionnaire and mental health scales, including depression and anxiety, were assessed...
January 4, 2024: Molecular Autism
https://read.qxmd.com/read/38161392/periconceptional-serum-creatinine-and-risk-of-childhood-autism-spectrum-disorder-a-research-letter
#40
JOURNAL ARTICLE
Ziv Harel, Nivethika Jeyakumar, Yuguang Kang, Maria P Velez, Natalie Dayan, Joel G Ray
BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental condition that manifests in early childhood, in which the maternal metabolic syndrome may be a risk factor. The kidney is a barometer of maternal metabolic syndrome duration and severity. OBJECTIVE: The main objective of this study is to determine whether periconceptional kidney function is associated with ASD in early childhood. DESIGN SETTING AND PARTICIPANTS: This retrospective population-based cohort study was completed in Ontario, Canada...
2024: Canadian Journal of Kidney Health and Disease
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