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otolaryngology oncology

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https://www.readbyqxmd.com/read/27849340/intra-arterial-cetuximab-for-the-treatment-of-recurrent-unresectable-head-and-neck-squamous-cell-carcinoma-%C3%A2
#1
Tristan Tham, Timothy G White, Shamik Chakraborty, Rohan R Lall, Rafael Ortiz, David J Langer, Deborah Shatzkes, Christopher G Filippi, Dennis Kraus, John A Boockvar, Peter D Costantino
IMPORTANCE: Management of recurrent head and neck squamous cell carcinoma is a common and challenging clinical problem in head and neck oncology. OBJECTIVE: Here we present the first reported case of super-selective intra-arterial (SSIA) microcatheter based local delivery of cetuximab for head and neck cancer. This technical report describes the techniques used to deliver the SSIA dose of cetuximab, as well as the patient outcome. DESIGN: This technical report is part of an ongoing Phase I Clinical Trial...
November 2016: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/27814782/spanish-consensus-for-the-management-of-sinonasal-tumors
#2
Fernando López, Juan José Grau, José Antonio Medina, Isam Alobid
Sinonasal tumors are rare neoplasms with distinctive clinical, aetiological and pathological features. The diagnosis and treatment of these tumours is challenging because of their low incidence, histological diversity and production of non-specific symptoms in the early stages. They have a variable prognosis depending on their histology, origin and staging. Their location, close to neurocritical structures, which are of special relevance to surgery and postoperative treatment, makes their treatment difficult and complex, leading to high morbidity and mortality...
November 1, 2016: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/27441153/skull-base-surgery-training-and-practice-patterns-among-recent-otolaryngology-fellowship-graduates
#3
Matthew M Dedmon, Garrett D Locketz, Kyle J Chambers, Matthew R Naunheim, Derrick T Lin, Stacey T Gray
OBJECTIVE: To collect data on skull base surgery training experiences and practice patterns of otolaryngologists that recently completed fellowship training. DESIGN: A 24-item survey was disseminated to physicians who completed otolaryngology fellowships in rhinology, head and neck oncology, or neurotology between 2010 and 2014. RESULTS: During a typical year, 50% of rhinologists performed more than 20 endoscopic anterior skull base cases, 83% performed fewer than 20 open cases, and were more confident performing advanced transplanum (p = 0...
August 2016: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/27386927/do-we-need-a-new-classification-of-parotid-gland-surgery
#4
Małgorzata Wierzbicka, Krzysztof Piwowarczyk, Hanna Nogala, Marzena Błaszczyńska, Michał Kosiedrowski, Cezary Mazurek
BACKGROUND: In February 2016 the European Salivary Gland Society (ESGS) presented and recommended classification of parotidectomies based on the anatomical I-V level division of parotid gland. The main goal of this paper is to present the new classification, and to answer the question if it is more precise compared to classic one. MATERIAL AND METHOD: 607 patients (315 man, 292 women) operated on for parotid tumours in a tertiary referral centre, Department of Otolaryngology, Head and Neck Surgery, Medical University of Poznań (502 benign and 105 malignant tumours)...
June 30, 2016: Otolaryngologia Polska. the Polish Otolaryngology
https://www.readbyqxmd.com/read/27375712/conventional-clinical-and-prognostic-variables-in-150-oral-squamous-cell-carcinoma-cases-from-the-indigenous-population-of-karachi
#5
Muhammad Mohiuddin Alamgir, Qamar Jamal, Talat Mirza
OBJECTIVE: To analyze clinical and prognostic variables of Oral Squamous Cell Carcinoma (OSCC) cases from the indigenous population of Karachi and to correlate with the common risk factor of tobacco habit. METHODS: The study was conducted at Ziauddin University, Karachi. One hundred fifty OSCC cases were collected from the Oncology Department of Ziauddin University Hospital, North Nazimabad, Karachi and Otolaryngology ward of Civil Hospital, Karachi, during 2011 and 2015...
May 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27356556/the-admission-patterns-of-octogenerians-nonagenerians-and-centenarians-to-the-department-of-otoloaryngology
#6
Doron Sagiv, Lela Migirov, Noga Lipschitz, Elad Dagan, Eran Glikson, Michael Wolf, Eran E Alon
Life expectancy in Israel has risen by almost 6 years during the last 25 years, and the proportion of people 65 years of age or older is expected to reach 12 % of the total population by 2020. A substantial increase in the workload for Otolaryngologists and Head and Neck surgeons is anticipated. Our goal was to characterize the admissions of patients 80 years of age and older to the Department of Otolaryngology, Head and Neck Surgery in a tertiary medical center. The study group included all patients 80 years of age and older who were admitted to the Department of OTOHNS in our institute between 2009 and 2013...
June 29, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27301380/do-audition-electives-impact-match-success
#7
Elizabeth Higgins, Linnie Newman, Katherine Halligan, Margaret Miller, Sally Schwab, Lynn Kosowicz
PURPOSE: The authors sought to determine the value of the audition elective to the overall success of medical students in the match. METHOD: The authors surveyed 1,335 fourth-year medical students at 10 medical schools in 2013. The study took place over a 2-month period immediately following the match. Medical students were emailed a 14-question survey and asked about audition electives, rank order, and cost of 'away' rotations. RESULTS: One hundred percent of students wishing to match in otolaryngology, neurosurgery, plastic surgery, radiation oncology, and urology took the audition electives...
2016: Medical Education Online
https://www.readbyqxmd.com/read/27283472/design-and-rationale-of-a-prospective-multi-institutional-registry-for-patients-with-sinonasal-malignancy
#8
Daniel M Beswick, F Christopher Holsinger, Michael J Kaplan, Nancy J Fischbein, Wendy Hara, A Dimitrios Colevas, Quynh-Thu Le, Gerald J Berry, Peter H Hwang
OBJECTIVES/HYPOTHESIS: Assessment of patients with sinonasal malignancy is challenging due to the low disease incidence and diverse histopathology. The current literature is composed mainly of retrospective studies with heterogeneous cohorts, and the rarity of cases limits our understanding of disease characteristics and treatment outcomes. We describe the development of a prospective, multi-institutional registry that utilizes cloud-based computing to evaluate treatment outcomes in patients with sinonasal cancer...
September 2016: Laryngoscope
https://www.readbyqxmd.com/read/27235871/fluid-collection-in-the-retropharyngeal-space-a-wide-spectrum-of-various-emergency-diseases
#9
REVIEW
Hayato Tomita, Tsuneo Yamashiro, Hirotaka Ikeda, Atsuko Fujikawa, Yoshiko Kurihara, Yasuo Nakajima
Fluid collections in the retropharyngeal space (RPS) result from a wide spectrum of diseases, including retropharyngeal abscess, cervical osteomyelitis, and calcific tendinitis of the longus colli muscle. These conditions should be managed by different specialties; beginning with care in the emergency room, physicians from orthopedics, pediatrics, otolaryngology, and oncology are in charge of the treatment. Since these diseases demonstrate similar fluid collections in the RPS on computed tomography (CT) and magnetic resonance imaging (MRI), the radiologist's diagnosis based on the characteristic imaging findings is very important to identify the primary disease...
July 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/27209507/international-medical-graduates-in-radiation-oncology-historical-trends-and-comparison-with-other-medical-specialties
#10
Vivek Verma, Chirag Shah, Tim Lautenschlaeger, Chi Lin, Sushil Beriwal, Weining Zhen, Minesh P Mehta, Anthony L Zietman
PURPOSE: This is the first National Resident Matching Program analysis evaluating historical patterns of international medical graduates (IMGs) in radiation oncology (RO) and providing comparison with American (MD) medical graduates (AMGs), osteopathic students (DOs), unfilled positions, and other specialties. METHODS AND MATERIALS: National Resident Matching Program data for IMGs were available from 2003 to 2015, with limited data for other specialty matches. The following RO-specific figures were obtained per year: total positions available; total matched positions; number of unfilled positions; and number of IMG, AMG, and DO matches...
July 15, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27178510/resident-fatigue-in-otolaryngology-residents-a-web-based-survey
#11
Andrew M Nida, Benjamin J Googe, Andrea F Lewis, Warren L May
IMPORTANCE: Resident fatigue has become a point of emphasis in medical education and its effects on otolaryngology residents and their patients require further study. OBJECTIVE: The purpose of our study was to evaluate the prevalence and nature of fatigue in otolaryngology residents, evaluate various quality of life measures, and investigate associations of increased fatigue with resident safety. STUDY DESIGN: Anonymous survey. SETTING: Internet based...
May 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/26940153/analysis-of-national-institutes-of-health-funding-to-departments-of-urology
#12
Jason Silvestre, Divyansh Agarwal, David I Lee
OBJECTIVE: To elucidate the current portfolio of National Institutes of Health (NIH) funding to departments of urology at U.S. medical schools. MATERIALS AND METHODS: The NIH Research Portfolio Online Reporting Tools Expenditures and Results was used to generate a comprehensive analysis of NIH research grants awarded to urology departments during 2014. Costs, mechanisms, and institutes were summarized with descriptive statistics. Demographic data were obtained for principal investigators and project abstracts were categorized by research type and area...
May 2016: Urology
https://www.readbyqxmd.com/read/26926305/impact-of-1607-1g-2g-mmp1-gene-polymorphism-on-the-morbidity-and-clinical-course-of-chronic-rhinosinusitis-with-nasal-polyps
#13
Paweł Molga, Wojciech Fendler, Maciej Borowiec, Wioletta Pietruszewska
UNLABELLED: Polyps within the nose and nasal sinuses are symptoms of both local conditions such as chronic bacterial or fungal rhinosinusitis, and systemic diseases such as cystic fibrosis, hypogammaglobulinemia, NSAID hypersensitivity syndrome, bronchial asthma as well as Kartagener's syndrome, Young's syndrome, Churg-Strauss' syndrome and Woakes' syndrome. The pathomechanism responsible for formation of nasal polyps remains a matter of dispute as well as the subject of numerous studies...
February 29, 2016: Otolaryngologia Polska. the Polish Otolaryngology
https://www.readbyqxmd.com/read/26840960/a-multidisciplinary-approach-to-castleman-disease-of-the-neck
#14
Alexandra A Shams, Mostafa M Ahmed, Nicholas J Scalzitti, Della L Howell, Jordan M Hall, John L Ritter, Stephen C Maturo
Castleman disease (CD) is a rare lymphoproliferative disorder that occurs in adults and rarely in the pediatric population. The disease is characterized by slowly enlarging masses that can form anywhere within the lymphatic system. It is an uncommon cause of a neck mass in both children and adults that presents insidiously and nonspecifically. A 21-year-old woman was referred to the otolaryngology service because of an asymptomatic neck mass found incidentally on computed tomographic imaging 15 months earlier...
February 2016: Southern Medical Journal
https://www.readbyqxmd.com/read/26826883/neurofibromatosis-type-2-service-delivery-in-england
#15
S K Lloyd, D G Evans
Neurofibromatosis type 2 (NF2) is a complex disease characterized by the development of multiple schwannomas, especially vestibular schwannomas, as well as other types of benign tumours including meningioma and spinal ependymoma. Due to its multisystem nature, the management of NF2 requires a multidisciplinary approach. In England, the delivery of care for NF2 patients has been centralized to four-"hub" centres in Manchester, Cambridge, Oxford and London each having associated "spoke" centres. Each centre has a core multidisciplinary team consisting of genetics, otolaryngology, neurosurgery, paediatrics, neurology, audiology, radiology, psychology, physiotherapy, specialist nurses and administrative staff...
January 27, 2016: Neuro-Chirurgie
https://www.readbyqxmd.com/read/26799413/spinal-epidural-abscess-following-glossectomy-and-neck-dissection-a-case-report
#16
Esther Cheng, Eric Thorpe, Richard Borrowdale
INTRODUCTION: Spinal epidural abscess is an uncommon but potentially life threatening entity that rarely occurs after otolaryngology procedures. PRESENTATION OF CASE: We report a case of a diabetic patient who presented with a lumbar spinal epidural abscess eight days after head and neck oncologic surgery. Magnetic resonance imaging revealed an L4 spinal epidural abscess. Cultures from the spinal epidural abscess, blood, urine, and the previous neck incision grew Klebsiella pneumoniae...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/26557767/osteosarcoma-of-the-larynx
#17
Piotr Sawicki, Wojciech Każmierczak, Łukasz Szylberg, Andrzej Marszałek
Malignant neoplasms of the larynx are divided into epithelial and non-epithelial. Non-epithelial neoplasms include, among others, mesenchymal chondrosarcomas and osteosarcomas. Few cases of laryngeal osteosarcomas described in the literature were usually treated by surgery without the need to use adjuvant radio- or chemotherapy. Few authors propose the initial application of radiotherapy or high-dose chemotherapy. Our study presents a very rare case of a woman treated due to laryngeal osteosarcoma. We have also presented diagnostic difficulties preceding a decision to perform radical surgery...
2015: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/26388248/the-risk-of-venous-thromboembolism-in-ent-and-head-neck-surgery
#18
Carlos Chiesa Estomba, Teresa Rivera Schmitz, Carla Cristina Ossa Echeverri, Frank Alberto Betances Reinoso, Alejandra Osorio Velasquez, Carmelo Santidrian Hidalgo
OBJECTIVES: Venous thromboembolic disease (VTD) includes deep vein thrombosis (DVT) and pulmonary embolism (PE), thus is one of the most feared postoperative complications developed by patients at any surgical department, because of high morbidity and mortality associated with it. MATERIALS AND METHODS: We performed a retrospective study including all patients operated on at the Otolaryngology Head and Neck Department (tertiary hospital) between January 2009 and December 2013...
2015: Otolaryngologia Polska. the Polish Otolaryngology
https://www.readbyqxmd.com/read/26388244/intracranial-complications-from-sinusitis
#19
Witold Szyfter, Aleksandra Kruk-Zagajewska, Anna Bartochowska, Łukasz Borucki
INTRODUCTION: Despite increasingly better diagnostic and therapeutic methods intracranial sinogenic complications, invariably pose a direct threat to the lives of patients and a challenge for otolaryngologists. AIM: The aim of the study was to analyze patients with intracranial sinogenic complications treated at the Department of Otolaryngology and Otolaryngological Oncology of Poznań University of Medical Sciences in the years 2000-2013. MATERIAL AND METHODS: Analysis covered the period from January 2000 to December 2013...
2015: Otolaryngologia Polska. the Polish Otolaryngology
https://www.readbyqxmd.com/read/26320052/frozen-section-guiding-the-hands-of-surgeons
#20
Eleanor R McIntosh, Shuko Harada, Joseph Drwiega, Margaret S Brandwein-Gensler, Jennifer Gordetsky
Frozen section (FS) analysis is a powerful tool that can provide a rapid diagnosis, directing operative management. However, FSs can also be misused. We consider an FS to be "inappropriate" when it does not influence operative management or immediate patient care. Not only can inappropriate FSs compromise diagnostic material, they can impact turnaround time of other FSs. We evaluated the utilization of FSs at our institution and assessed influence on intraoperative management. Frozen sections performed at the University of Alabama at Birmingham Hospital in 2013 were stratified by surgical subspecialty...
October 2015: Annals of Diagnostic Pathology
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