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S S Rushley, D Kim, C S Bretherton, M-S Ahn
Bretherton et al. (2004) used the Special Sensor Microwave Imager (SSM/I) version 5 product to derive an exponential curve that describes the relationship between precipitation and column relative humidity (CRH) over the tropical oceans. The curve, which features a precipitation pickup at a CRH of about 0.75 and a rapid increase of precipitation with CRH after the pickup, has been widely used in the studies of the tropical atmosphere. This study re-examines the moisture-precipitation relationship by using the version 7 SSM/I data, in which several biases in the previous version are corrected, and evaluates the relationship in the Coupled Model Intercomparison Project phase 5 (CMIP5) models...
January 28, 2018: Geophysical Research Letters
Urmimala Maitra, Robert A House, James W Somerville, Nuria Tapia-Ruiz, Juan G Lozano, Niccoló Guerrini, Rong Hao, Kun Luo, Liyu Jin, Miguel A Pérez-Osorio, Felix Massel, David M Pickup, Silvia Ramos, Xingye Lu, Daniel E McNally, Alan V Chadwick, Feliciano Giustino, Thorsten Schmitt, Laurent C Duda, Matthew R Roberts, Peter G Bruce
The search for improved energy-storage materials has revealed Li- and Na-rich intercalation compounds as promising high-capacity cathodes. They exhibit capacities in excess of what would be expected from alkali-ion removal/reinsertion and charge compensation by transition-metal (TM) ions. The additional capacity is provided through charge compensation by oxygen redox chemistry and some oxygen loss. It has been reported previously that oxygen redox occurs in O 2p orbitals that interact with alkali ions in the TM and alkali-ion layers (that is, oxygen redox occurs in compounds containing Li+ -O(2p)-Li+ interactions)...
March 2018: Nature Chemistry
Ronit Beck-Fruchter, Israel Gavish, Shira Baram, Yoel Geslevich, Amir Weiss
OBJECTIVE: Thromboelastography (TEG) is a viscoelastic test of hemostasis which allows measurement of the processes of clot initiation, propagation, stabilization, and dissolution in real time. In this study we aimed to evaluate the alterations in coagulation as measured by TEG during In Vitro Fertilization (IVF) stimulation cycles and to investigate whether final oocyte maturation with recombinant hCG (rhCG) versus GnRH agonist results in a different coagulation state. STUDY DESIGN: This is a prospective observational study which included fifty-three normogonadotrophic women...
February 10, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Puneet Bagga, Stephen Pickup, Rachelle Crescenzi, Daniel Martinez, Arijitt Borthakur, Kevin D'Aquilla, Anup Singh, Gaurav Verma, John A Detre, Joel Greenberg, Hari Hariharan, Ravinder Reddy
Glutamate Chemical Exchange Saturation Transfer (GluCEST) MRI is a recently developed technique to image glutamate. In the present study, we evaluated the reproducibility and background contamination to the GluCEST and source of the GluCEST changes in a mouse model of Parkinson's disease. Repeated measurements in five mice demonstrated an intra-animal coefficient of variation (CV) of GluCEST signal to be 2.3 ± 1.3% and inter-animal CV of GluCEST to be 3.3 ± 0.3%. Mice were treated with MPTP to create a localized striatal elevation of glutamate...
February 13, 2018: Scientific Reports
John C Pickup
No abstract text is available yet for this article.
February 2018: Diabetes Technology & Therapeutics
Amanda M Perri, Zvonimir Poljak, Cate Dewey, John C S Harding, Terri L O'Sullivan
The first case of porcine epidemic diarrhea (PED) in Canada was diagnosed in January 2014 in Ontario, approximately 9 months after PED emerged in the United States. An early investigation of the Canadian outbreak suspected that the probable source of the virus was contaminated feed. The objective of this study was to evaluate the role of feed and other possible factors in the early phase of the PED outbreak in Canadian swine herds. The study period of interest for this case-control study was January 22nd to March 1st, 2014...
February 1, 2018: Preventive Veterinary Medicine
Gabriel J Diaz, Melissa S Parade, Sean L Barton, Brett R Fajen
The present study investigated differences in the pickup of information about the size and location of an obstacle in the path of locomotion. The main hypothesis was that information about obstacle location is most useful when it is sampled at a specific time during the approach phase, whereas information about obstacle size can be sampled at any point during the last few steps. Subjects approached and stepped over obstacles in a virtual environment viewed through a head-mounted display. In Experiment 1, a horizontal line on the ground indicating obstacle location was visible throughout the trial while information about obstacle height and depth was available only while the subject was passing through a viewing window located at one of four locations along the subject's path...
2018: PloS One
Joshua A Eudailey, Maria L Dennis, Morgan E Parker, Bonnie L Phillips, Tori N Huffman, Camden P Bay, Michael G Hudgens, Roger W Wiseman, Justin J Pollara, Genevieve G Fouda, Guido Ferrari, David J Pickup, Pamela A Kozlowski, Koen K A Van Rompay, Kristina De Paris, Sallie R Permar
Mother-to-child transmission (MTCT) of human immunodeficiency virus type 1 (HIV-1) contributes to an estimated 150,000 new infections annually. Maternal vaccination has proven safe and effective at mitigating the impact of other neonatal pathogens and is one avenue toward generating the potentially protective immune responses necessary to inhibit HIV-1 infection of infants through breastfeeding. In the present study, we tested the efficacy of a maternal vaccine regimen consisting of a modified vaccinia virus Ankara (MVA) 1086...
January 2018: MSphere
Matthew P Fox, Sophie J Pascoe, Amy N Huber, Joshua Murphy, Mokgadi Phokojoe, Marelize Gorgens, Sydney Rosen, David Wilson, Yogan Pillay, Nicole Fraser-Hurt
INTRODUCTION: In 2016, South Africa's National Department of Health (NDOH) launched the National Adherence Guidelines for Chronic Diseases for phased implementation throughout South Africa. Early implementation of a 'minimum package' of eight interventions in the Adherence Guidelines for patients with HIV is being undertaken at 12 primary health clinics and community health centres in four provinces. NDOH and its partners are evaluating the impact of five of the interventions in four provinces in South Africa...
January 21, 2018: BMJ Open
Y M Mala, Ruchi Prasad, Nilanchali Singh, C P Baweja, Reva Tripathi, Niharika Yedla
This study was included 60 women with suspected genital tuberculosis, attending outpatient department of a tertiary care hospital. The aim was to evaluate the role and accuracy of laparoscopy in the diagnosis of genital tuberculosis. The patients were investigated for tuberculosis with Erythrocyte Sedimentation Rate, Montoux, chest X-ray, serum ELISA, CA125, ultrasonography, endometrial biopsy and laparoscopic biopsy. Culture or histopathology was taken as a gold standard for confirming the cases of genital tuberculosis...
January 2018: Indian Journal of Tuberculosis
ZhiJie Li, Rui Song, Shiwei He, Mingkai Bi
Custom bus routes need to be optimized to meet the needs of a customized bus for personalized trips of different passengers. This paper introduced a customized bus routing problem in which trips for each depot are given, and each bus stop has a fixed time window within which trips should be completed. Treating a trip as a virtual stop was the first consideration in solving the school bus routing problem (SBRP). Then, the mixed load custom bus routing model was established with a time window that satisfies its requirement and the result were solved by Cplex software...
2018: PloS One
Olufunmilola Abraham, Dayna S Alexander, Loren J Schleiden, Delesha M Carpenter
OBJECTIVES: This study aimed to describe the barriers and facilitators that influence community pharmacists' ability to provide medication counseling to pediatric patients. METHODS: Semistructured interviews (n = 16) were conducted with pharmacy staff at 3 community pharmacies in 2 Eastern states. The interview guide elicited pharmacy staff experiences interacting with children and their perceived barriers and facilitators to providing medication counseling. Transcripts were reviewed for accuracy and a codebook was developed for data analysis...
November 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
Zulfadhli Mohamad, Simon Dixon, Christopher Harte
This paper proposes a technique that estimates the locations along the string of the plucking event and the magnetic pickup of an electric guitar based on the autocorrelation of the spectral peaks. To improve accuracy, a method is introduced to flatten the spectrum before applying the autocorrelation function to the spectral peaks. The minimum mean squared error between the autocorrelation of the observed data and the electric guitar model is found in order to estimate the model parameters. The accuracy of the algorithm is tested on various plucking positions on all open strings for each pickup configuration...
December 2017: Journal of the Acoustical Society of America
Bianca Szkuta, Kaye N Ballantyne, Bas Kokshoorn, Roland A H van Oorschot
Questions relating to how DNA from an individual got to where it was recovered from and the activities associated with its pickup, retention and deposition are increasingly relevant to criminal investigations and judicial considerations. To address activity level propositions, investigators are typically required to assess the likelihood that DNA was transferred indirectly and not deposited through direct contact with an item or surface. By constructing a series of Bayesian networks, we demonstrate their use in assessing activity level propositions derived from a recent legal case involving the alleged secondary transfer of DNA to a surface following a handshaking event...
March 2018: Forensic Science International. Genetics
Sara Pinelli, Paolo Giovanni Artini, Stefano Basile, Maria Elena Rosa Obino, Claudia Sergiampietri, Diana Giannarelli, Giovanna Simi, Vito Cela
PURPOSE: During the transitional phase of premature ovarian insufficiency (POI), sporadic resumption of ovulation is possible because of fluctuation of hormonal levels but the chance of spontaneous pregnancy is low, and the main perspective of childbearing in these women is egg donation or adoption. The purpose of the study was to verify whether treatment with estrogens in POI patients in transitional phase could reduce FSH levels and to evaluate if this pre-treatment could improve reproductive outcomes of in vitro fertilization (IVF)...
December 5, 2017: Journal of Assisted Reproduction and Genetics
A R Gilman, G Younes, S Tannus, W Y Son, P Chan, W Buckett
The objective of this study was to assess whether testicular-retrieved spermatozoa improve reproductive outcomes compared to fresh ejaculate in women with poor ovarian response and a history of previous ART failure. The study was performed as a retrospective case-control study at a university-based reproductive center in Montreal, Quebec, Canada. Eighteen poor-responder patients were matched 3 : 1 with 54 controls. Poor responders were defined as those with ≤3 oocytes retrieved at oocyte pickup. Cases were identified as poor responders, and only those with previous IVF failure(s) as an indication for testicular-retrieved spermatozoa were included...
January 2018: Andrology
Timnit Gebru, Jonathan Krause, Yilun Wang, Duyun Chen, Jia Deng, Erez Lieberman Aiden, Li Fei-Fei
The United States spends more than $250 million each year on the American Community Survey (ACS), a labor-intensive door-to-door study that measures statistics relating to race, gender, education, occupation, unemployment, and other demographic factors. Although a comprehensive source of data, the lag between demographic changes and their appearance in the ACS can exceed several years. As digital imagery becomes ubiquitous and machine vision techniques improve, automated data analysis may become an increasingly practical supplement to the ACS...
December 12, 2017: Proceedings of the National Academy of Sciences of the United States of America
Stijn Fias, Thijs Stuyver
The recent source and sink potential approach by Pickup et al. [J. Chem. Phys. 143, 194105 (2015)] is extended to Hartree-Fock and density functional theory, allowing the calculation of the transmission and the visualization of ballistic currents through molecules at these levels of theory. This visualization allows the study of the transmission process in real-space, providing an important tool to better understand the conduction process.
November 14, 2017: Journal of Chemical Physics
Patrick W Fowler, Irene Sciriha, Martha Borg, Victoria E Seville, Barry T Pickup
Within the source-and-sink-potential model, a complete characterisation is obtained for the conduction behaviour of alternant π-conjugated hydrocarbons (conjugated hydrocarbons without odd cycles). In this model, an omni-conductor has a molecular graph that conducts at the Fermi level irrespective of the choice of connection vertices. Likewise, an omni-insulator is a molecular graph that fails to conduct for any choice of connections. We give a comprehensive classification of possible combinations of omni-conducting and omni-insulating behaviour for molecular graphs, ranked by nullity (number of non-bonding orbitals)...
October 28, 2017: Journal of Chemical Physics
Kathleen D Klinich, Miriam A Manary, Laura A Malik, Carol A Flannagan, Jessica S Jermakian
OBJECTIVE: Investigate vehicle factors associated with child restraint tether use and misuse in pickup trucks and evaluate four labeling interventions designed to educate consumers on proper tether use. METHODS: Volunteer testing was performed with 24 subjects and four different pickup trucks. Each subject performed eight child restraint installations among the four pickups using two forward-facing restraints: a Britax Marathon G4.1 and an Evenflo Triumph. Vehicles were selected to represent four different implementations of tether anchors among pickups: plastic loop routers (Chevrolet Silverado), webbing routers (Ram), back wall anchors (Nissan Frontier), and webbing routers plus metal anchors (Toyota Tundra)...
October 30, 2017: Traffic Injury Prevention
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