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https://www.readbyqxmd.com/read/28227194/exploring-neuro-muscular-synergies-of-reaching-movements-with-unified-independent-component-analysis
#1
Fiorenzo Artoni, Elvira Pirondini, Alessandro Panarese, Silvestre Micera, Fiorenzo Artoni, Elvira Pirondini, Alessandro Panarese, Silvestre Micera, Elvira Pirondini, Alessandro Panarese, Fiorenzo Artoni, Silvestro Micera
The coordinated recruitment of group of muscles through muscles synergies is known to simplify the control of movements. However, how and to what extent such control scheme is encoded at a cortical level is poorly understood. So far, electroencephalography (EEG) and electromyography (EMG) have been used, separately, to investigate the cortical regions of the human brain which may be involved in activating muscle synergies. Here we aim at extending these results by looking for a hierarchical relationship between cortical and muscular sources of activity (neuro-muscular synergies) with a unified analysis of independent components (IC) simultaneously extracted from both EEG and EMG signals...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227192/acoustic-evaluation-of-pirfenidone-on-patients-with-combined-pulmonary-fibrosis-emphysema-syndrome
#2
Sonia Charleston-Villalobos, Norma Castaneda-Villa, Ramon Gonzalez-Camarena, M Mejia-Avila, H Mateos-Toledo, Tomas Aljama-Corrales, Sonia Charleston-Villalobos, Norma Castaneda-Villa, Ramon Gonzalez-Camarena, M Mejia-Avila, H Mateos-Toledo, Tomas Aljama-Corrales, Tomas Aljama-Corrales, Ramon Gonzalez-Camarena, Sonia Charleston-Villalobos, Norma Castaneda-Villa, M Mejia-Avila, H Mateos-Toledo
The combined pulmonary fibrosis emphysema syndrome (CPFES) overall has a poor prognosis with a 5-year survival of 35-80%. Consequently, to evaluate possible positive effects on patients of novel agents as pirfenidone is relevant. However, the efficacy of pirfenidone in CPFES patients is still not well-known. In this study we propose an alternative to evaluate the effects of pirfenidone treatment on CPFES patients via acoustic information. Quantitative analysis of discontinuous adventitious lung sounds (DLS), known as crackles, has been promising to detect and characterize diverse pulmonary pathologies...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227092/eeg-based-single-trial-detection-of-errors-from-multiple-error-related-brain-activity
#3
Guofa Shou, Lei Ding, Guofa Shou, Lei Ding, Guofa Shou, Lei Ding
A key ability of the human brain is to monitor erroneous events and adjust behaviors accordingly. Electrophysiological and neuroimaging studies have demonstrated different brain activities related to errors. Meanwhile, the recognition of error-related brain activity as one aspect of performance monitoring has been reported for potential applications in clinical neuroscience and brain-machine interface, where single-trial analysis and classification would provide novel insights on dynamic brain responses to errors...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226624/a-comparison-of-independent-component-analysis-algorithms-and-measures-to-discriminate-between-eeg-and-artifact-components
#4
Dhani Dharmaprani, Hoang K Nguyen, Trent W Lewis, Dylan DeLosAngeles, John O Willoughby, Kenneth J Pope, Dhani Dharmaprani, Hoang K Nguyen, Trent W Lewis, Dylan DeLosAngeles, John O Willoughby, Kenneth J Pope, John O Willoughby, Hoang K Nguyen, Dylan DeLosAngeles, Trent W Lewis, Dhani Dharmaprani, Kenneth J Pope
Independent Component Analysis (ICA) is a powerful statistical tool capable of separating multivariate scalp electrical signals into their additive independent or source components, specifically EEG or electroencephalogram and artifacts. Although ICA is a widely accepted EEG signal processing technique, classification of the recovered independent components (ICs) is still flawed, as current practice still requires subjective human decisions. Here we build on the results from Fitzgibbon et al. [1] to compare three measures and three ICA algorithms...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226405/comparative-effectiveness-of-long-acting-beta2-agonist-combined-with-a-long-acting-muscarinic-antagonist-or-inhaled-corticosteroid-in-chronic-obstructive-pulmonary-disease
#5
Jennifer C Samp, Min J Joo, Glen T Schumock, Gregory S Calip, A Simon Pickard, Todd A Lee
INTRODUCTION: Several dual bronchodilator fixed dose inhaler medications were recently approved for the treatment of chronic obstructive pulmonary disease (COPD). These products combine a long-acting beta2 -agonist (LABA) and long-acting muscarinic antagonist (LAMA). In clinical trials, the separate mechanisms of the bronchodilators resulted in improved lung function. COPD treatment guidelines currently recommend combination LABA/LAMA as alternative therapy to combination LABA/ inhaled corticosteroid (ICS)...
February 22, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28220767/asthma-control-in-adult-patients-treated-with-a-combination-of-inhaled-corticosteroids-and-long-acting-beta-2-agonists-a-prospective-observational-study
#6
Barbara Rogala, Paweł Majak, Joanna Glück, Tomasz Dębowski
INTRODUCTION    Asthma is a highly prevalent disease that often requires maintenance therapy. Combined inhaled corticosteroid and long-acting beta-2 agonist (ICS/LABA) inhalers are one of the available maintenance treatment options.  OBJECTIVES    This prospective observational study aimed to assess asthma control in patients treated with ICS/LABA inhalers and to identify factors related to controlled asthma. PATIENTS AND METHODS    A total of 5789 asthma sufferers from Poland were enrolled in a prospective, observational study and treated with one of the following combined ICS/LABA inhalers at clinically appropriate doses: beclomethasone/formoterol, fluticasone/salmeterol, or budesonide/formoterol...
January 18, 2017: Polskie Archiwum Medycyny Wewnętrznej
https://www.readbyqxmd.com/read/28220083/risperidone-effects-on-brain-dynamic-connectivity-a-prospective-resting-state-fmri-study-in-schizophrenia
#7
Kristin K Lottman, Nina V Kraguljac, David M White, Charity J Morgan, Vince D Calhoun, Allison Butt, Adrienne C Lahti
Resting-state functional connectivity studies in schizophrenia evaluating average connectivity over the entire experiment have reported aberrant network integration, but findings are variable. Examining time-varying (dynamic) functional connectivity may help explain some inconsistencies. We assessed dynamic network connectivity using resting-state functional MRI in patients with schizophrenia, while unmedicated (n = 34), after 1 week (n = 29) and 6 weeks of treatment with risperidone (n = 24), as well as matched controls at baseline (n = 35) and after 6 weeks (n = 19)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28218986/risk-factors-hindering-asthma-symptoms-control-in-saudi-children-and-adolescents
#8
Rabih Halwani, Alejandro Vazquez-Tello, Nour Horanieh, Said Dulgom, Zohair Al-Aseri, Nouf Al-Khamis, Zubaida Al-Sum, Hamdan Al-Jahdali, Saleh Al-Muhsen
BACKGROUND: Maintaining well control of asthma symptoms can help preventing exacerbations and its associated complications. The Asthma Control Test (ACT) can rapidly assess the effectiveness of asthma management plan and therapy. OBJECTIVE: To identify risk factors associated with uncontrolled asthma symptoms in young Saudi asthmatics (3-17 years-old). METHODS: In this cross-sectional hospital-based survey, the ACT was administered to 297 asthmatic children/adolescents, recruited at the emergency department (ED) of two major hospitals...
February 20, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28217536/analysis-of-sugars-and-ph-in-commercially-available-soft-drinks-in-saudi-arabia-with-a-brief-review-on-their-dental-implications
#9
Ali Mohamed Idris, Nandimandalam Venkata Vani, Dhafi A Almutari, Mohammed A Jafar, Nezar Boreak
OBJECTIVE: To determine the amount of sugar and pH in commercially available soft drinks in Jazan, Saudi Arabia. This was further compared with their labeled values in order to inform the regulations. The effects of these drinks on teeth is reviewed. MATERIALS AND METHODS: Ten brands of popular soft drinks including 6 regular carbonated drinks and 4 energy drinks were obtained from the local markets. Their pH was determined using a pH meter. The amount of total sugar, glucose, fructose, and sucrose was estimated using high performance liquid chromatography (using Dionex ICS 5000 ion chromatography) at the Saudi Food and Drug Authority...
December 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28217081/blinker-automated-extraction-of-ocular-indices-from-eeg-enabling-large-scale-analysis
#10
Kelly Kleifges, Nima Bigdely-Shamlo, Scott E Kerick, Kay A Robbins
Electroencephalography (EEG) offers a platform for studying the relationships between behavioral measures, such as blink rate and duration, with neural correlates of fatigue and attention, such as theta and alpha band power. Further, the existence of EEG studies covering a variety of subjects and tasks provides opportunities for the community to better characterize variability of these measures across tasks and subjects. We have implemented an automated pipeline (BLINKER) for extracting ocular indices such as blink rate, blink duration, and blink velocity-amplitude ratios from EEG channels, EOG channels, and/or independent components (ICs)...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28216891/effects-of-potassium-sulfate-k2so4-on-the-element-contents-polyphenol-content-antioxidant-and-antimicrobial-activities-of-milk-thistle-silybum-marianum
#11
Gulsum Yaldiz
BACKGROUND: Silybum marianum L. (Milk thistle) is native to the Mediterranean basin and is now widespread throughout the world. It's sprout is used as a herbal medicine for the treatment of liver disease for centuries. The seeds of milk thistle contain silymarin, an isomeric mixture of flavonolignans [silybin, silychristin, and silydianin]. Silymarin acts as a strong anti-hepatotoxic. OBJECTIVES: The objective of this study was to evaluate the influences of potassium sulfate [K2SO4] fertilizer doses on polyphenol content, some nutrient elements, antioxidant and antimicrobial activities of milk thistle at experimental fields of Ordu University in Turkey...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28215072/encapsulation-of-ethylene-gas-into-granular-cold-water-soluble-starch-structure-and-release-kinetics
#12
Linfan Shi, Xiong Fu, Chin Ping Tan, Qiang Huang, Bin Zhang
Ethylene gas was introduced into granular cold-water soluble (GCWS) starches using a solid encapsulation method. The morphological and structural properties of the novel inclusion complexes (ICs) were characterized using scanning electron microscopy, X-ray diffractometry, and Raman spectroscopy. The V-type single helix of GCWS starches was formed through controlled gelatinization and ethanol precipitation, and was approved to host ethylene gas. The controlled release characteristics of ICs were also investigated at various temperature and relative humidity conditions...
February 20, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28213798/digital-rectal-examination-in-the-evaluation-of-rectovaginal-septal-defects
#13
Suneetha Rachaneni, Ixora Kamisan Atan, Ka Lai Shek, Hans Peter Dietz
INTRODUCTION AND HYPOTHESIS: The objective was to evaluate the diagnostic potential of digital rectal examination in the identification of a true rectocele. METHODS: This is a retrospective observational study utilising 187 archived data sets of women presenting with lower urinary tract symptoms and/or pelvic organ prolapse between August 2012 and November 2013. Evaluation included a standardised interview, ICS-POPQ, rectal examination and 4D translabial ultrasound...
February 17, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28210222/icariside-ii-a-broad-spectrum-anti-cancer-agent-reverses-beta-amyloid-induced-cognitive-impairment-through-reducing-inflammation-and-apoptosis-in-rats
#14
Yuanyuan Deng, Long Long, Keke Wang, Jiayin Zhou, Lingrong Zeng, Lianzi He, Qihai Gong
Beta-amyloid (Aβ) deposition, associated neuronal apoptosis and neuroinflammation are considered as the important factors which lead to cognitive deficits in Alzheimer's disease (AD). Icariside II (ICS II), an active flavonoid compound derived from Epimedium brevicornum Maxim, has been extensively used to treat erectile dysfunction, osteoporosis and dementia in traditional Chinese medicine. Recently, ICS II attracts great interest due to its broad-spectrum anti-cancer property. ICS II shows an anti-inflammatory potential both in cancer treatment and cerebral ischemia-reperfusion...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28208871/clinical-utility-of-fractional-exhaled-nitric-oxide-feno-as-a-biomarker-to-predict-severity-of-disease-and-response-to-inhaled-corticosteroid-ics-in-asthma-patients
#15
Revathy Neelamegan, Vinodkumar Saka, Kadhiravan Tamilarasu, Manju Rajaram, Sandhiya Selvarajan, Adithan Chandrasekaran
INTRODUCTION: Bronchial asthma is a common chronic inflammatory airway disease diagnosed and is based on symptomatic history and Pulmonary Function Tests (PFT). Fractional exhaled Nitric Oxide (FeNO) is exclusively a non-invasive biomarker of on-going eosinophilic airway inflammation which remains unpredictable only with PFTs. FeNO measurement is recommended in predicting asthma severity and Inhaled Corticosteroid (ICS) response but further research is required to understand its clinical utility and agreement with current recommendations in a specific population...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28203072/-real-life-inhaled-corticosteroid-withdrawal-in-copd-a-subgroup-analysis-of-daccord
#16
Claus Vogelmeier, Heinrich Worth, Roland Buhl, Carl-Peter Criée, Nadine S Lossi, Claudia Mailänder, Peter Kardos
Many patients with chronic obstructive pulmonary disease (COPD) receive inhaled corticosteroids (ICSs) without a clear indication, and thus, the impact of ICS withdrawal on disease control is of great interest. DACCORD is a prospective, noninterventional 2-year study in the primary and secondary care throughout Germany. A subgroup of patients were taking ICS prior to entry - 1,022 patients continued to receive ICS for 2 years; physicians withdrew ICS on entry in 236 patients. Data from these two subgroups were analyzed to evaluate the impact of ICS withdrawal...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28199361/bombyx-mori-and-aedes-aegypti-form-multi-functional-immune-complexes-that-integrate-pattern-recognition-melanization-coagulants-and-hemocyte-recruitment
#17
Dennis R Phillips, Kevin D Clark
The innate immune system of insects responds to wounding and pathogens by mobilizing multiple pathways that provide both systemic and localized protection. Key localized responses in hemolymph include melanization, coagulation, and hemocyte encapsulation, which synergistically seal wounds and envelop and destroy pathogens. To be effective, these pathways require a targeted deposition of their components to provide protection without compromising the host. Extensive research has identified a large number of the effectors that comprise these responses, but questions remain regarding their post-translational processing, function, and targeting...
2017: PloS One
https://www.readbyqxmd.com/read/28194189/day-time-variation-of-serum-periostin-in-asthmatic-adults-treated-with-ics-laba-and-adults-without-asthma
#18
Rachel Caswell-Smith, Terrianne Cripps, Thom Charles, Alexander Hosking, Meghana Handigol, Cecile Holweg, John Matthews, Mark Holliday, Corentin Maillot, James Fingleton, Mark Weatherall, Richard Beasley, Irene Braithwaite
BACKGROUND: We aimed to determine the effect of sampling time during the day on serum periostin levels in adult participants with and without asthma. METHODS: Serum periostin was measured at 2-h intervals from 0800 to 1800 h in 16 adult participants with stable asthma prescribed inhaled corticosteroid and long-acting beta-agonist therapy, and in 16 otherwise healthy participants without asthma. Mixed linear models were used to compare time zero (08:00 h) with subsequent measurement time for serum periostin for both groups...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/28193441/double-layer-ensemble-monitoring-of-non-gaussian-processes-using-modified-independent-component-analysis
#19
Chudong Tong, Ting Lan, Xuhua Shi
The modified independent component analysis (MICA) was proposed mainly to obtain a consistent solution that cannot be ensured in the original ICA algorithm and has been widely investigated in multivariate statistical process monitoring (MSPM). Within the MICA-based non-Gaussian process monitoring circle, there are two main problems, i.e., the selection of a proper non-quadratic function for measuring non-Gaussianity and the determination of dominant ICs for constructing latent subspace, have not been well attempted so far...
February 10, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28192574/primary-care-asthma-management-inhaled-corticosteroids-and-other-clinical-pearls
#20
Zachary Marcus, Nanah Suk Park
Most children in the United States with intermittent, mild, and moderate persistent asthma are cared for by primary care practitioners (PCPs). Despite inhaled corticosteroids (ICS) being highly effective at controlling asthma symptoms, many PCPs are uncomfortable prescribing these medications. Cumbersome guidelines, increasing numbers of medication choices, and concerns regarding side effects are some of the barriers to prescribing ICS for children with asthma. This article serves as a quick-start guide for PCPs that (1) condenses the routine diagnosis and management of asthma into concise clinical tools for children who would benefit from ICS therapy and (2) provides clinical pearls to aid in the treatment of mild- to moderate-persistent asthma...
February 1, 2017: Pediatric Annals
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