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https://www.readbyqxmd.com/read/28213097/self-assembled-tumor-targeting-hyaluronic-acid-nanoparticles-for-photothermal-ablation-in-orthotopic-bladder-cancer
#1
Tingsheng Lin, Ahu Yuan, Xiaozhi Zhao, Huibo Lian, Junlong Zhuang, Wei Chen, Qing Zhang, Guangxiang Liu, Shiwei Zhang, Wei Chen, Wenmin Cao, Chengwei Zhang, Jinhui Wu, Yiqiao Hu, Hongqian Guo
: Bladder cancer is one of the most frequent malignancies in the urinary system. Radical cystectomy is inevitable when bladder cancer progresses to a muscle-invasive disease. However, cystectomy still causes a high risk of death and a low quality of life (such as ureter-abdomen ostomy, uroclepsia for ileal-colon neobladder). Therefore, more effective treatments as well as bladder preservation are needed. We developed self-assembled tumor-targeting hyaluronic acid-IR-780 nanoparticles for photothermal ablation in over-expressing CD44 (the receptor for HA) bladder cancer, which show high tumor selectivity, high treatment efficacy, good bioavailability, and excellent biocompatibility...
February 14, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28205051/impact-of-preoperative-steroid-or-immunosuppressant-use-on-short-term-outcomes-following-colectomy-in-crohn-s-disease-patients
#2
N Valizadeh, A C A Murray, K Suradkar, A Al-Mazrou, R P Kiran
BACKGROUND: Evaluating the impact of steroid or immunosuppressants (SI) therapy prior to colectomy in Crohn's disease (CD) patients on postoperative septic and colectomy-specific outcomes using the American College of Surgeons (ACS)-National Surgical Quality Improvement Program (NSQIP)-targeted colectomy database. METHODS: All CD patients undergoing colectomy were retrieved from the 2012-2013 NSQIP-targeted database. Thirty-day postoperative outcomes were compared for patients who were on steroids or immunosuppressants (SI) within the 30 days prior to colectomy to the others using univariable and multivariable analyses...
February 15, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28202185/pediatric-colonic-volvulus-a-single-institution-experience-and-review
#3
REVIEW
Sami Tannouri, Aditi Hendi, Elizabeth Gilje, Leslie Grissom, Douglas Katz
BACKGROUND/PURPOSE: Pediatric colonic volvulus is both rare and underreported. Existing literature consists only of case reports and small series. We present an analysis of cases (n=11) over 15 years at a single institution, focusing on workup and diagnosis. METHODS: This was an institutional review board approved single-institution retrospective chart review of 11 cases of large bowel volvulus occurring over 15 years (2000-2015). RESULTS: In our series, the most common presenting symptoms were abdominal pain and distention...
February 2, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28192627/home-visits-as-part-of-a-new-care-pathway-iaid-to-improve-quality-of-care-and-quality-of-life-in-ostomy-patients-a-cluster-randomised-stepped-wedge-trial
#4
M F Sier, R J Oostenbroek, M G W Dijkgraaf, G J Veldink, W A Bemelman, A Pronk, E J Spillenaar-Bilgen, W Kelder, C Hoff, D T Ubbink
BACKGROUND: Morbidity in patients with an 'ostomy is high. A new care pathway, including perioperative home visits by enterostomal therapists, was studied to assess whether more elaborate education and closer guidance could reduce stoma-related complications and improve quality of life, at acceptable cost. METHODS: Patients requiring an ileostomy or colostomy, for any inflammatory or malignant bowel disease, were included in a 15-centre cluster-randomised 'stepped-wedge' study...
February 13, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28182642/prophylactic-mesh-placement-for-the-prevention-of-parastomal-hernias-the-presto-systematic-review-and-meta-analysis
#5
Frank Pianka, Pascal Probst, Anne-Valerie Keller, Daniel Saure, Kathrin Grummich, Markus W Büchler, Markus K Diener
BACKGROUND: Parastomal hernia (PH) is the most common complication after ostomy formation. Prophylactic mesh placement may be effective in reducing the rate of PH at the stoma site. The aims of this systematic review were to summarize the evidence with regard to the safety and effectiveness in comparison with the standard procedure without mesh placement and to identify important risk constellations. METHOD: A systematic literature search was performed in PubMed, EMBASE and the Cochrane library with no language or date restrictions...
2017: PloS One
https://www.readbyqxmd.com/read/28178060/modified-beef-tongue-model-for-fourth-degree-laceration-repair-simulation
#6
Jana D Illston, Alicia C Ballard, David R Ellington, Holly E Richter
BACKGROUND: An existing model for fourth-degree laceration repair uses beef tongue with plastic or vinyl tubing. This modified model substitutes beef tripe for the anal mucosa and chicken leg muscles for the anal sphincter muscle analogs to create a realistic model. METHOD: Tripe is tunneled through the body of the trimmed beef tongue and sutured like an ostomy to simulate the anal canal. The tongue is incised toward the tripe "anal canal." Chicken leg muscles are tunneled from the incision out to the cut edges of the beef tongue to create anal sphincter muscle analogs...
February 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28156625/clinical-and-health-care-setting-of-patients-admitted-at-pain-control-center-hospice-of-solofra-a-feasibility-model-of-end-of-life-care-in-the-avellino-province-of-italy
#7
Carmela Fasano, Luisa M Rizzo, A M Strollo, Elena De Vinco, Vincenzo Landolfi, Elena Altieri, Mario Nicola Vittorio Ferrante, Sergio Canzanella, Giuseppe Servillo, Lucia Genua, Maddalena Zampi, Gaetano D'Onofrio
: 59 Background: The Pain Control Center Hospice of Solofra (Italy) is managed with a mixed public / private, the first experience in the Campania region.We have evaluated the treatment procedures and the clinical outcome to make a comparison by between 123 evaluable patients in palliative care in 2015 and 232 evaluable patients in the biennium 2012-2014. METHODS: The following characteristics: patient gender, mean hospitalization time, differentiation between cancer and non cancer patients, medical weapon use, venous access type, enteral and parenteral feeding, pain killer use,Karnofsky scale...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28144209/functional-disorders-of-constipation-paradoxical-puborectalis-contraction-and-increased-perineal-descent
#8
REVIEW
Isaac Payne, Leander M Grimm
Paradoxical puborectalis contraction (PPC) and increased perineal descent (IPD) are subclasses of obstructive defecation. Often these conditions coexist, which can make the evaluation, workup, and treatment difficult. After a thorough history and examination, workup begins with utilization of proven diagnostic modalities such as cinedefecography and anal manometry. Advancements in technology have increased the surgeon's diagnostic armamentarium. Biofeedback and pelvic floor therapy have proven efficacy for both conditions as first-line treatment...
February 2017: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/28137299/a-cross-sectional-study-of-quality-of-life-in-a-cohort-of-enteral-ostomy-patients-presenting-to-a-tertiary-care-hospital-in-a-developing-country-in-south-asia
#9
Umesh Jayarajah, Dharmabandhu N Samarasekera
BACKGROUND: Enteral ostomy creation affects the quality of life (QOL) of stoma patients significantly. Studying the QOL and its determinants is important as it may help in the early identification of those with poor QOL leading to appropriate intervention. This study was aimed to assess the possible contributory factors of QOL of stoma patients. METHODS: A cross sectional study was conducted among 43 ostomy patients who presented for follow up at a surgical clinic of a tertiary care hospital in Sri Lanka over a period of 1 year...
January 31, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28122534/an-increase-in-physical-activity-after-colorectal-cancer-surgery-is-associated-with-improved-recovery-of-physical-functioning-a-prospective-cohort-study
#10
Moniek van Zutphen, Renate M Winkels, Fränzel J B van Duijnhoven, Suzanne A van Harten-Gerritsen, Dieuwertje E G Kok, Peter van Duijvendijk, Henk K van Halteren, Bibi M E Hansson, Flip M Kruyt, Ernst J Spillenaar Bilgen, Johannes H W de Wilt, Jaap J Dronkers, Ellen Kampman
BACKGROUND: The influence of physical activity on patient-reported recovery of physical functioning after colorectal cancer (CRC) surgery is unknown. Therefore, we studied recovery of physical functioning after hospital discharge by (a) a relative increase in physical activity level and (b) absolute activity levels before and after surgery. METHODS: We included 327 incident CRC patients (stages I-III) from a prospective observational study. Patients completed questionnaires that assessed physical functioning and moderate-to-vigorous physical activity shortly after diagnosis and 6 months later...
January 25, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28112647/a-retrospective-analysis-of-factors-affecting-early-stoma-complications
#11
Umit Koc, Kerem Karaman, Ismail Gomceli, Tahsin Dalgic, Ilter Ozer, Murat Ulas, Metin Ercan, Erdal Bostanci, Musa Akoglu
Despite advances in surgical techniques and products for stoma care, stoma-related complications are still common. A retrospective analysis was performed of the medical records of 462 consecutive patients (295 [63.9%] female, 167 [36.1 %] male, mean age 55.5 ± 15.1 years, mean body mass index [BMI] 25.1 ± 5.2) who had undergone stoma creation at the Gastroenterological Surgery Clinic of Turkiye Yuksek İhtisas Teaching and Research Hospital between January 2008 and December 2012 to examine the incidence of early (ie, within 30 days after surgery) stoma complications and identify potential risk factors...
January 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/28112646/the-ostomy-q-development-and-psychometric-validation-of-an-instrument-to-evaluate-outcomes-associated-with-ostomy-appliances
#12
Beenish Nafees, Mikkel Rasmussen, Andrew LLoyd
Using an ostomy appliance can affect many aspects of a person's health-related quality of life (HRQL). A 2-part, descrip- tive study was designed to develop and validate an instrument to assess quality-of-life outcomes related to ostomy ap- pliance use. Study inclusion/exclusion criteria stipulated participants should be 18 to 85 years of age, have an ileostomy or colostomy, used an appliance for a minimum of 3 months without assistance, and able to complete an online survey. All participants provided sociodemographic and clinical information...
January 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/28100944/ostomy-in-nontraumatic-conditions-our-experience-and-review-of-the-literature
#13
Kenan Büyükaşık, Bünyamin Gürbulak, Emre Özoran, Yiğit Düzköylü, Esin Kabul Gürbulak, Aziz Arı, Hasan Bektaş
A number of nontraumatic acute abdomen can result in peritonitis leading to sepsis. In emergent conditions, various procedures like segmentary colectomy and/or subtotal colectomy with anastomosis, Hartmann's procedure, transverse colectomy, and/or expandable metallic stent (SEMS) placement can be performed, considering the status of the patient and the facilitaties of the institution. In our study, we examined the cases diagnosed as acute abdomen without the history of trauma, which had lead to a procedure requiring colostomy...
December 2016: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28078117/effect-of-gender-on-psychosocial-adjustment-of-colorectal-cancer-survivors-with-ostomy
#14
Sital Gautam, Anju Poudel
BACKGROUND: Stoma can pose extensive challenges for colorectal cancer survivors. Identifying the psychological and social adjustment among them and how it differs by gender will aid in identifying those particularly at risk of having poor adjustment and in planning programs to improve their adjustment. The purpose of this study was to determine the effect of gender on psychosocial adjustment of colorectal cancer survivors with ostomy. METHODS: A descriptive cross sectional study was carried out in the stoma clinic of B...
December 2016: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28060005/exploration-of-health-status-illness-perceptions-coping-strategies-psychological-morbidity-and-quality-of-life-in-individuals-with-fecal-ostomies
#15
Simon R Knowles, Davina Tribbick, William R Connell, David Castle, Michael Salzberg, Michael A Kamm
PURPOSE: In a previous paper focusing on the common sense model (CSM) for ostomies in people with inflammatory bowel disease, cancer, and diverticular disease, we reported that (1) illness perceptions were directly related to illness status, and both illness perceptions and coping strategies (maladaptive coping) directly influenced anxiety and depression; (2) self-efficacy and emotion-focused coping style ameliorated depression but not anxiety; and (3) time since surgery was associated with improved health status, a reduction in negative illness perceptions, and increased emotional-focused coping...
January 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28060000/embracing-the-concept-defining-the-practice-and-changing-the-outcome-setting-the-standard-for-medical-adhesive-related-skin-injury-interventions-in-woc-nursing-practice
#16
Stephanie Yates, Laurie McNichol, Steven B Heinecke, Mikel Gray
Medical adhesive-related skin injury (MARSI) is a comparatively new category of skin damage. Our current understanding of MARSI originates from an interdisciplinary consensus conference held in 2012 that generated and disseminated 25 statements pertaining to the assessment, prevention, and management of MARSI, along with gaps in research and knowledge related to this area. The 2012 MARSI Consensus Group also challenged each organization to refine the original statements to make them more relevant to their particular area of practice...
January 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28059999/context-for-practice-trends-in-pressure-injury-prevention-use-of-convexity-in-ostomy-care-and-prevention-of-catheter-associated-urinary-tract-infections-in-children
#17
Mikel Gray
No abstract text is available yet for this article.
January 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28059917/characterization-of-readmission-by-day-of-rehospitalization-after-colorectal-surgery
#18
Ahmed M Al-Mazrou, Kunal Suradkar, Christine M Mauro, Ravi P Kiran
BACKGROUND: Factors associated with readmission stratified by the day of postdischarge rehospitalization after colorectal surgery have not been characterized previously. OBJECTIVE: The purpose of this study was to identify factors leading to readmission on a day-to-day basis after discharge from colorectal surgery. DESIGN: This was a retrospective analysis of patients readmitted within 30-days after colorectal surgery. Reasons and factors associated with readmission each day after discharge were evaluated...
February 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28029380/do-hospital-factors-impact-readmissions-and-mortality-after-colorectal-resections-at-minority-serving-hospitals
#19
Elizabeth M Hechenbleikner, Chaoyi Zheng, Samuel Lawrence, Young Hong, Nawar M Shara, Lynt B Johnson, Waddah B Al-Refaie
BACKGROUND: Minority-serving hospitals have greater readmission rates after operative procedures including colectomy; however, little is known about the contribution of hospital factors to readmission risk and mortality in this setting. This study evaluated the impact of hospital factors on readmissions and inpatient mortality after colorectal resections at minority-serving hospitals in the context of patient- and procedure-related factors. METHODS: More than 168,000 patients who underwent colorectal resections in 374 California hospitals (2004-2011) were analyzed using the State Inpatient Database and American Hospital Association Hospital Survey data...
October 27, 2016: Surgery
https://www.readbyqxmd.com/read/28002175/executive-summary-enhanced-recovery-after-surgery-best-practice-guideline-for-care-of-patients-with-a-fecal-diversion
#20
Debbie Miller, Emily Pearsall, Debra Johnston, Monica Frecea, Marg McKenzie
Enhanced Recovery After Surgery (ERAS) is a multimodal program developed to decrease postoperative complications, improve patient safety and satisfaction, and promote early discharge. In the province of Ontario, Canada, a standardized approach to the care of adult patients undergoing elective colorectal surgery (including benign and malignant diseases) was adopted by 15 hospitals in March 2013. All colorectal surgery patients with or without an ostomy were included in the ERAS program targeting a length of stay of 3 days for colon surgery and 4 days for rectal surgery...
January 2017: Journal of Wound, Ostomy, and Continence Nursing
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