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H Takayama, T Sohma, S Sunano
1. When the blood from rabbit or from human was subjected to hemolysis in the test tubes, K-concentration of serum was elevated to about 40 mEq/l. According to these result, the effects of K ion of the concentration up to 30 mM on the contractile response were studied. 2. When the K-concentration was elevated to 10 mM or 20 mM, a transient relaxation was observed. The relaxation, however, was transient and reversed into contraction. No relaxation was observed when K-concentration was elevated gradually. 3. Basilar artery showed higher sensitivity than carotid artery to the elevation of extracellular K-concentration and showed a contractile response to lower K-concentration...
December 1980: Nihon Heikatsukin Gakkai Zasshi
M Sasaki, J Takenawa, H Kanamaru, Y Komatz
We used prazosin (alpha-blocker) for preoperative management of three patients with pheochromocytoma. All patients had episodic hypertension with headache and palpitation. The first dose of prazosin caused blood pressure to drop in one of three patients, but no significant hypotension was observed. By the daily dose of 6-8 mg prazosin with or without propranolol, subjective symptoms of the patients were improved and the frequency of the hypertensive attack was decreased Operations were carried out without significant complications, but phentramine and nitroprusside were required because of rapid rise of blood pressure during induction of anesthesia and surgical manipulation...
January 1986: Hinyokika Kiyo. Acta Urologica Japonica
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