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https://www.readbyqxmd.com/read/28516493/diagnosis-and-treatment-of-dermatophytosis-in-dogs-and-cats-clinical-consensus-guidelines-of-the-world-association-for-veterinary-dermatology
#1
REVIEW
Karen A Moriello, Kimberly Coyner, Susan Paterson, Bernard Mignon
BACKGROUND: Dermatophytosis is a superficial fungal skin disease of cats and dogs. The most common pathogens of small animals belong to the genera Microsporum and Trichophyton. It is an important skin disease because it is contagious, infectious and can be transmitted to people. OBJECTIVES: The objective of this document is to review the existing literature and provide consensus recommendations for veterinary clinicians and lay people on the diagnosis and treatment of dermatophytosis in cats and dogs...
June 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28513809/oral-gentamicin-therapy-for-carbapenem-resistant-klebsiella-pneumoniae-gut-colonization-in-hematologic-patients-a-single-center-experience
#2
Paola Lambelet, Carlo Tascini, Simona Fortunato, Alessandro Stefanelli, Federico Simonetti, Chiara Vettori, Alessandro Leonildi, Francesco Menichetti
The mortality for carbapenem-resistant Klebsiella pneumoniae (KPC-Kp) infection ranges from 18 to 48% depending on the type of therapy. Mortality rates in hematologic patients are even higher, up to 85%. Gut decontamination with oral gentamicin might be an option to avoid a subsequent KPC-Kp infection in colonized patients. We treated 14 hematologic patients with oral gentamicin, 80 mg four times daily, for 7 to 25 days in order to eradicate KPC-Kp from the gut, starting oral gentamicin therapy when possible after the discontinuation of systemic antibiotic therapy...
May 17, 2017: New Microbiologica
https://www.readbyqxmd.com/read/28435376/comparative-evaluation-of-antimicrobial-efficacy-of-an-alternative-natural-agent-for-disinfection-of-toothbrushes
#3
R Vignesh, C Vishnu Rekha, Parisa Norouzi Baghkomeh, Sankar Annamalai, Ditto Sharmin
OBJECTIVE: The aim of this study was to assess the antimicrobial potency of aqueous extract of Psidium guajava leaves in two different concentrations as a toothbrush disinfectant against three oral bacterial species. MATERIALS AND METHODS: Aqueous extracts of P. guajava leaves were prepared at 20% and 30% concentrations and 0.2% chlorhexidine was used as control. The toothbrushes were equally divided into 9 groups with 10 toothbrushes per disinfectant, which were contaminated with Streptococcus mutans, Lactobacillus acidophilus, and Enterococcus faecalis...
January 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28376842/pattern-of-acute-organophosphorus-poisoning-at-university-of-gondar-teaching-hospital-northwest-ethiopia
#4
Getnet Mequanint Adinew, Assefa Belay Asrie, Eshetie Melese Birru
BACKGROUND: Despite the apparent benefits of organophosphate compounds (OPCs) acute organophosphate (OP) pesticide poison is an increasing problem worldwide. In a country like Ethiopia, where agriculture is a major component of the economy, these compounds are readily available to the general public. There is paucity of evidence from Ethiopia showing the pattern of organophosphate poisoning (OPP) in healthcare facilities. The objective of this study was to evaluate retrospectively the pattern of acute OPP at the University of Gondar Teaching Hospital in northwest Ethiopia, during September 2010 through December 2014 was conducted...
April 4, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28352183/clinical-characteristics-of-zinc-phosphide-poisoning-in-thailand
#5
Satariya Trakulsrichai, Natcha Kosanyawat, Pongsakorn Atiksawedparit, Charuwan Sriapha, Achara Tongpoo, Umaporn Udomsubpayakul, Panee Rittilert, Winai Wananukul
OBJECTIVE: The objectives of this study were to describe the clinical characteristics and outcomes of poisoning by zinc phosphide, a common rodenticide in Thailand, and to evaluate whether these outcomes can be prognosticated by the clinical presentation. MATERIALS AND METHODS: A 3-year retrospective cohort study was performed using data from the Ramathibodi Poison Center Toxic Exposure Surveillance System. RESULTS: In total, 455 poisonings were identified...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28320561/the-effects-of-oral-rinse-with-0-2-and-2-chlorhexidine-on-oropharyngeal-colonization-and-ventilator-associated-pneumonia-in-adults-intensive-care-units
#6
Farid Zand, Leili Zahed, Parisa Mansouri, Freshte Dehghanrad, Maryam Bahrani, Mohammad Ghorbani
BACKGROUND: Ventilator Associated Pneumonia (VAP) is the most common nosocomial infection in Intensive Care Units (ICUs) which increases the length of ICU stay, duration of mechanical ventilation, and mortality. The present study used an oral care protocol and compared the effects of two different concentrations of chlorhexidine on reduction of oropharyngeal colonization and VAP. MATERIALS AND METHODS: This study was performed on 114 patients from trauma, surgery, neurosurgery, and general ICUs randomly allocated to two groups under oral care with 0...
March 1, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28267670/selective-digestive-decontamination-in-critically-ill-children-a-survey-of-canadian-providers
#7
Srinivas Murthy, Nazima Pathan, Brian H Cuthbertson
BACKGROUND: Selective digestive decontamination of the digestive tract involves the routine administration of oral, gastric, and intravenous antibiotics to mechanically ventilated children to prevent hospital-acquired infections. It has a strong evidence base in adults, with limited pediatric evidence. Current utilization of this intervention among pediatric physicians in North America is unknown. METHODS: An electronic survey administered to pediatric critical care and pediatric infectious disease providers in Canada...
June 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28133524/comparison-of-activated-charcoal-and-sodium-polystyrene-sulfonate-resin-efficiency-on-reduction-of-amitriptyline-oral-absorption-in-rat-as-treatments-for-overdose-and-toxicities
#8
Gholamhossein Yousefi, Mohammad Bizhani, Akram Jamshidzadeh, Saeid Gholamzadeh
OBJECTIVES: Comparative in vivo studies were carried out to determine the adsorption characteristics of amitriptyline (AMT) on activated charcoal (AC) and sodium polystyrene sulfonate (SPS). AC has been long used as gastric decontamination agent for tricyclic antidepressants and SPS has showed to be highly effective on in-vitro drugs adsorption. MATERIALS AND METHODS: Sprague-Dawley male rats were divided into six groups. Group I: control, group II: AMT 200 mg/kg as single dose orally, group III and IV: AC 1g/kg as single dose orally 5 and 30 min after AMT administration respectively, and group 5 and 6: SPS 1 g/kg as single dose orally 5 and 30 min after AMT administration, respectively...
January 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28118221/prevention-of-ventilator-associated-pneumonia
#9
Gianluigi Li Bassi, Tarek Senussi, Eli Aguilera Xiol
PURPOSE OF REVIEW: Ventilator-associated pneumonia (VAP) is an iatrogenic disease. Here we appraise recent advancements in the development and testing of strategies to prevent VAP. We also provide recommendations on the most promising interventions that should be applied. RECENT FINDINGS: In the last year, preventive bundles have consistently let to a reduction of VAP. A few trials on endotracheal tubes (ETTs) with novel cuffs failed to translate positive bench findings into clinical settings...
April 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/28117914/chemotherapeutic-decontamination-of-dental-implants-colonized-by-mature-multispecies-oral-biofilm
#10
Sebastien Dostie, Lubna T Alkadi, Gethin Owen, Jiarui Bi, Ya Shen, Markus Haapasalo, Hannu S Larjava
AIM: No studies have tested disinfectants on mature multispecies oral biofilms on titanium substrata. The aim of this study was to investigate the efficacy of commonly used antimicrobial agents in decontamination of multispecies mature oral biofilm on sandblasted, large-grit, acid-etched (SLA) titanium implants. METHODS: SLA titanium disks were inoculated with dental plaque and cultured anaerobically for 21 days. The disks were rinsed with 0.9% NaCl, exposed for 2 min...
January 24, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28042438/the-treatment-of-peri-implant-diseases-a-new-approach-using-hybenx-%C3%A2-as-a-decontaminant-for-implant-surface-and-oral-tissues
#11
M A Lopez, M Andreasi Bassi, L Confalone, F Silvestre, C Arcuri
PURPOSE: The aim of the present study is to demonstrate the efficacy of HyBeNX® to decontaminate the implant surface, both in the case mucositis and severe peri-implantitis and to allow future bone regeneration. MATERIALS AND METHODS: We describe three case reports of peri-implantitis successfully treated with HyBeNX®. In our study, we have used microbiological tests to demonstrate the efficacy of HyBeNX® in decreasing bacterial load. RESULTS: The microbiological results of the clinical cases described show that there was a reduction in the total bacterial count after treatment...
July 2016: Oral & Implantology
https://www.readbyqxmd.com/read/28039835/toxicokinetics-of-chlordecone-in-goats-implications-for-risk-management-in-french-west-indies
#12
Agnès Fournier, Cyril Feidt, Marie-Laure Lastel, Harry Archimede, Jean-Pierre Thome, Maurice Mahieu, Guido Rychen
The former use of chlordecone (CLD) in the French West Indies has resulted in long-term pollution of soils. CLD is known to be potentially transferred towards animal products of animals reared outdoors, mainly through accidental soil ingestion. Several studies indicate that soil bound CLD is bioavailable when administered to farm animals. Currently there is a need to quantify the level of CLD absorption and its toxicokinetic characteristics in the ruminant and particularly in the goat. These are considered as important farm species in the French West Indies...
March 2017: Chemosphere
https://www.readbyqxmd.com/read/27991646/materials-for-retrograde-filling-in-root-canal-therapy
#13
REVIEW
Xiangyu Ma, Chunjie Li, Liuhe Jia, Yan Wang, Wenwen Liu, Xuedong Zhou, Trevor M Johnson, Dingming Huang
BACKGROUND: Root canal therapy is a sequence of treatments involving root canal cleaning, shaping, decontamination and obturation. It is conventionally performed through a hole drilled into the crown of the affected tooth, namely orthograde root canal therapy. For teeth that cannot be treated with orthograde root canal therapy, or for which it has failed, retrograde root filling, which seals the root canal from the root apex, is a good alternative. Many materials, such as amalgam, zinc oxide eugenol and mineral trioxide aggregate (MTA), are generally used...
December 17, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27931875/efficacy-of-antimicrobial-photodynamic-therapy-in-the-disinfection-of-acrylic-denture-surfaces-a-systematic-review
#14
REVIEW
Sergio Varela Kellesarian, Tariq Abduljabbar, Fahim Vohra, Hans Malmstrom, Michael Yunker, Tammy Varela Kellesarian, Georgios E Romanos, Fawad Javed
BACKGROUND: the aim of the present systematic review was to assess the efficacy of antimicrobial photodynamic therapy (aPDT) in the disinfection of acrylic denture surfaces. METHODS: in order to address the focused question: "Is aPDT more effective in decontaminating denture surfaces compared with traditional denture-disinfection techniques?" an electronic search without time or language restrictions was conducted up to November 2016 in indexed databases using different key words...
December 5, 2016: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/27852955/microbiological-efficacy-of-early-mrsa-treatment-in-cystic-fibrosis-in-a-randomised-controlled-trial
#15
Marianne Sponer Muhlebach, Valeria Beckett, Elena Popowitch, Melissa B Miller, Arthur Baines, Nicole Mayer-Hamblett, Edith T Zemanick, Wynton C Hoover, Jill M VanDalfsen, Preston Campbell, Christopher H Goss
OBJECTIVE: To evaluate microbiological effectiveness, that is, culture negativity of a non-blinded eradication protocol (Rx) compared with observation (Obs) in clinically stable cystic fibrosis participants with newly positive methicillin resistant Staphylococcusaureus (MRSA) cultures. DESIGN: This non-blinded trial randomised participants ages 4-45 years with first or early (≤2 positive cultures within 3 years) MRSA-positive culture without MRSA-active antibiotics within 4 weeks 1:1 to Rx or Obs...
April 2017: Thorax
https://www.readbyqxmd.com/read/27828768/clinical-comparison-of-two-photosensitizers-for-oral-cavity-decontamination
#16
Hérica Adad Ricci Donato, Sebastião Pratavieira, Clovis Grecco, Aldo Brugnera-Júnior, Vanderlei Salvador Bagnato, Cristina Kurachi
OBJECTIVE: In this study, we aim to compare the photodynamic inactivation (PDI) effects of two different photosensitizers (PS), Photogem(®) and Natural Curcumin, irradiated with light-emitted diodes (LED) at 630 and 450 nm, respectively. BACKGROUND: The current antimicrobial mouthwash for oral hygiene has several drawbacks. In this context, PDI is an alternative technique to inactivate pathogenic microbes in mucosa and in periodontal tissue. Furthermore, there are numerous infectious diseases that may affect the oral cavity, motivating the use of PDI in dentistry...
February 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27811563/systemic-fungal-infections-in-donors-for-corneal-transplantation
#17
Sheila Pabon, Thomas D Lindquist, Thomas D Miller, Bennie H Jeng
PURPOSE: To determine the prevalence of postkeratoplasty fungal infection when corneal tissue from donors with a recent medical history of oral thrush or respiratory, urine, wound, sputum, bronchial, tracheal, or throat culture positive for fungus is identified before recovery and after decontamination of the corneal tissue with 5% povidone-iodine flush to the donors' eyes during recovery. METHODS: This is a prospective analysis of corneas from 42 donors with a documented medical history of fungus or positive fungal culture, which were recovered between January 2010 and November 2010...
January 2017: Cornea
https://www.readbyqxmd.com/read/27695915/amoxicillin-clavulanic-acid-and-ciprofloxacin-treated-spf-mice-as-gnotobiotic-model
#18
Miroslav Popper, Soňa Gancarčíková, Marián Maďar, Dagmar Mudroňová, Gabriela Hrčková, Radomíra Nemcová
The experiment was carried out on 24 SPF BALB/c female mice and lasted for 15 days with a 5-day antibiotic (ATB) treatment and then 10 days without ATB treatment. The aim of our study was to acquire an animal model with reduced and controlled microflora and, at the same time, to ensure that the good health of these animals is maintained. Per oral administration of amoxicillin and clavulanate potassium in Amoksiklav (Sandoz, Slovenia) at a dose of 387.11 mg/kg body weight (0.2 ml of dilution per mouse) and subcutaneous administration of ciprofloxacin in Ciloxan (Alcon, Spain) at a dose of 18...
November 2016: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/27536698/ricin-toxicity-clinical-and-molecular-aspects
#19
Mohammad Moshiri, Fatemeh Hamid, Leila Etemad
Seeds of the castor bean plant Ricinuscommunis L (CB) contain ricin toxin (RT), one of the most poisonous naturally-occurring substances known. Ricin toxin, a water-soluble glycoprotein that does not partition into the oil extract, is a ribosome-inactivating toxin composed of two chains, labeled A and B. Severity of the toxicity varies depending on the route of exposure to the toxin. Inhalational is the most toxic route, followed by oral ingestion. Orally-ingested RT accumulates in the liver and spleen but other cells are also affected...
April 2016: Reports of Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/27526283/antibiotic-mediated-modification-of-the-intestinal-microbiome-in-allogeneic-hematopoietic-stem-cell-transplantation
#20
REVIEW
J Whangbo, J Ritz, A Bhatt
Allogeneic hematopoietic stem cell transplantation (HSCT) is curative for many patients with severe benign and malignant hematologic disorders. The success of allogeneic HSCT is limited by the development of transplant-related complications such as acute graft-versus-host disease (GvHD). Early pre-clinical studies suggested that intestinal microflora contribute to the pathogenesis of acute GvHD, and that growth suppression or eradication of intestinal bacteria prevented the development of acute GvHD even in MHC-mismatched transplants...
February 2017: Bone Marrow Transplantation
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