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https://www.readbyqxmd.com/read/29356061/cohort-study-from-11-european-countries-highlighted-differences-in-the-use-and-efficacy-of-hypothermia-prevention-strategies-after-very-preterm-birth
#1
Emilija Wilson, Jennifer Zeitlin, Aurélie Piedvache, Bjoern Misselwitz, Kyllike Christensson, Rolf F Maier, Mikael Norman, Anna-Karin Edstedt Bonamy
AIM: This study investigated the different strategies used in 11 European countries to prevent hypothermia, which continues to affect a large proportion of preterm births in the region. METHODS: We examined the association between the reported use of hypothermia prevention strategies in delivery rooms and body temperatures on admission to neonatal intensive care units (NICUs) in 5,861 infants born at 22+0 - 31+6 weeks of gestation. The use of plastic bags, wraps, caps, exothermic heat and mattresses was investigated...
January 21, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29355168/reproductive-health-and-pregnancy-in-women-with-chronic-kidney-disease
#2
REVIEW
Kate S Wiles, Catherine Nelson-Piercy, Kate Bramham
Chronic kidney disease (CKD) is associated with reduced fertility and an increased risk of adverse pregnancy outcomes. Rates of pre-eclampsia, fetal growth restriction and preterm delivery increase incrementally with the severity of CKD and proteinuria. Pre-pregnancy counselling can facilitate informed decision-making. Safe and effective contraception is required for women who wish to delay or avoid pregnancy. Pregnancy planning for women who wish to conceive involves appropriate substitution of known teratogens - including mycophenolate mofetil, angiotensin blockers and cyclophosphamide - and can aid optimization of disease control...
January 22, 2018: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29355161/pre-and-post-ductal-oxygen-saturation-among-apparently-healthy-low-birth-weight-neonates
#3
Leo A Odudu, Beatrice N Ezenwa, Christopher I Esezobor, Ekanem N Ekure, Mathias T C Egri Okwaji, Chinyere V Ezeaka, Fidelis O Njokanma, Jejelola Ladele
INTRODUCTION: Reference values of oxygen saturation (SpO2) to guide care of low birth weight neonates have been obtained mainly from Caucasians. Data from African newborns are lacking. To determine the pre- and post-ductal SpO2values of low birth weight neonates within the first 72 h of life, compare SpO2values of moderate-late preterm and term low birth weight neonates and determine how mode of delivery affected SpO2in the first 24 h of life. METHODOLOGY: An observational descriptive study was carried out on apparently healthy low birth weight newborns weighing 1500 to ≤2499 g...
October 2017: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29353510/effects-of-passive-smoking-on-lung-function-tests-in-preschool-children-born-late-preterm-a-preventable-health-priority
#4
Ayla Gunlemez, İlkay Er, Canan Baydemir, Ayse Arisoy
OBJECTIVE: Late-preterm delivery is known to be associated with potential adverse effects on lung development. Passive smoking may result in alterations of pulmonary function in infants born late-preterm. Impulse oscillometry (IOS) is a noninvasive, rapid and practicable technique that can assess lung function. This study aimed to evaluate the effect of passive smoking on lung function tests in preschool children born late-preterm using IOS. METHODS: The study population consisted of a total of 139 children between 3 and 7 years of age born late-preterm who were being followed-up at our outpatient unit at the time of study period...
January 21, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29353262/preterm-human-milk-macronutrient-concentration-is-independent-of-gestational-age-at-birth
#5
Jan Maly, Iva Burianova, Veronika Vitkova, Eva Ticha, Martina Navratilova, Eva Cermakova
OBJECTIVE: To evaluate the amount of macronutrients in aggregate of human milk samples after preterm delivery during the first 2 months of lactation. METHODS: Analysis of the donated single milk samples, gained by complete emptying of the whole breast at the same daytime between 24+0 and 35+6 gestational age (GA), was designed as prospective observational cohort trial. Two milk samples were analysed every postnatal week up to the discharge from the hospital, week 9 or loss of lactation...
January 20, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29353261/impact-of-delivered-tidal-volume-on-the-occurrence-of-intraventricular-haemorrhage-in-preterm-infants-during-positive-pressure-ventilation-in-the-delivery-room
#6
Qaasim Mian, Po-Yin Cheung, Megan O'Reilly, Samantha K Barton, Graeme R Polglase, Georg M Schmölzer
BACKGROUND AND OBJECTIVES: Delivery of inadvertent high tidal volume (VT) during positive pressure ventilation (PPV) in the delivery room is common. High VT delivery during PPV has been associated with haemodynamic brain injury in animal models. We examined if VT delivery during PPV at birth is associated with brain injury in preterm infants <29 weeks' gestation. METHODS: A flow-sensor was placed between the mask and the ventilation device. VT values were compared with recently described reference ranges for VT in spontaneously breathing preterm infants at birth...
January 20, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29352467/systematic-misclassification-of-gestational-age-by-ultrasound-biometry-implications-for-clinical-practice-and-research-methodology-in-the-nordic-countries
#7
Alkistis Skalkidou, Merit Kullinger, Marios K Georgakis, Helle Kieler, Ulrik S Kesmodel
Historically, pregnancy dating has been based on self-reported information on first day of the last menstrual period. In the 1970s, ultrasound biometry was introduced as an alternative for pregnancy dating, and is now the leading method in Nordic countries. The use of ultrasound led to a reduction of postterm births and fewer inductions and is considered more precise than last menstrual period-based methods for pregnancy dating. Nevertheless, differences in early growth and specific situations, such as maternal obesity, can render its estimates less precise, leading to gestational age misclassification...
January 20, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29351561/preconception-use-of-cart-by-hiv-positive-pregnant-women-increases-the-risk-of-infants-being-born-small-for-gestational-age
#8
Ingrid J M Snijdewind, Colette Smit, Mieke H Godfried, Rachel Bakker, Jeannine F J B Nellen, Vincent W V Jaddoe, Elisabeth van Leeuwen, Peter Reiss, Eric A P Steegers, Marchina E van der Ende
BACKGROUND: The benefits of combination anti-retroviral therapy (cART) in HIV-positive pregnant women (improved maternal health and prevention of mother to child transmission [pMTCT]) currently outweigh the adverse effects due to cART. As the variety of cART increases, however, the question arises as to which type of cART is safest for pregnant women and women of childbearing age. We studied the effect of timing and exposure to different classes of cART on adverse birth outcomes in a large HIV cohort in the Netherlands...
2018: PloS One
https://www.readbyqxmd.com/read/29351170/risk-of-preterm-birth-following-late-pregnancy-exposure-to-nsaids-or-cox-2-inhibitors
#9
Anick Bérard, Odile Sheehy, Sylvie Girard, Jin-Ping Zhao, Sasha Bernatsky
Pregnant women may take non-steroidal anti-inflammatory drugs (NSAIDs), selective cyclooxygenase (COX)-2 inhibitors or biologic agents to relieve symptoms or manage disease flares in late pregnancy. We aimed to quantify the risk of prematurity associated with late pregnancy exposure to non-selective NSAIDs, selective COX-2 inhibitors and biologic agents. Using data from Quebec Pregnancy Cohort, we performed a population-based cohort study. We included all women who were covered by the Quebec Drug Plan and had a singleton livebirth between 1/1/1998 and 31/12/2009...
January 18, 2018: Pain
https://www.readbyqxmd.com/read/29349843/pregnancy-after-bariatric-surgery-maternal-and-fetal-outcomes-of-39-pregnancies-and-a-literature-review
#10
Maria Manuel Costa, Sandra Belo, Pedro Souteiro, João S Neves, Daniela Magalhães, Rita B Silva, Sofia C Oliveira, Paula Freitas, Ana Varela, Joana Queirós, Davide Carvalho
AIM: We aimed to evaluate the impact of bariatric surgery (BS) on maternal and fetal outcomes. METHODS: A retrospective, descriptive, observational study of 39 pregnant women who underwent BS in our institution between 2010 and 2014 was carried out. A sample of women who became pregnant after BS was evaluated, based on data concerning pregnancy, childbirth, and newborns. RESULTS: Of the 1182 patients who underwent BS at our institution during the study period, 1016 (85...
January 18, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29344987/prior-uterine-evacuation-and-the-risk-of-short-cervical-length-a-retrospective-cohort-study
#11
Rupsa C Boelig, Michela Villani, Eva Jiang, Kelly M Orzechowski, Vincenzo Berghella
OBJECTIVES: To determine whether a prior uterine evacuation procedure is associated with an increased risk of short cervical length (≤20 mm) in women without prior spontaneous preterm birth. METHODS: This work was a retrospective cohort study from January 2012 to December 2014 of singletons without prior spontaneous preterm birth with cervical length screening between 18 weeks and 23 weeks 6 days. Women with a prior miscarriage/abortion were excluded if management (medical, surgical, or expectant) was not specified...
January 18, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29343146/induction-of-labor-in-cases-of-late-preterm-isolated-oligohydramnios-is-it-justified
#12
Noa A Brzezinski-Sinai, Moshe Stavsky, Tal Rafaeli-Yehudai, Maayan Yitshak-Sade, Isaac Brzezinski-Sinai, Majdi Imterat, Salvatore Andrea Mastrolia, Offer Erez
OBJECTIVES: To analyze in a retrospective cohort study the outcomes of pregnancies with isolated oligohydramnios at the late preterm period (34-36.6 weeks of gestation). STUDY DESIGN: This retrospective cohort study included three groups of women: 1) Women with isolated oligohydramnios whose pregnancy was managed conservatively (n = 33 births); 2) women with isolated oligohydramnios who were managed actively (ie induction of labor) (n = 111 births); and 3) a control group including women with normal amount of amniotic fluid who had a spontaneous late preterm delivery (n = 10 445 births)...
January 17, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29343138/the-efficacy-of-myo-inositol-supplementation-to-prevent-gestational-diabetes-onset-a-meta-analysis-of-randomized-controlled-trials
#13
Jiang Xu, Shandong Ye
INTRODUCTION: The efficacy of myo-inositol supplementation to prevent gestational diabetes onset remains controversial. We conduct a systematic review and meta-analysis to explore the influence of myo-inositol supplementation on the incidence of gestational diabetes. METHODS: We search PubMed, Embase, Web of science, EBSCO, and Cochrane Library databases through November 2017 for randomized controlled trials (RCTs) assessing the effect of myo-inositol supplementation on gestational diabetes onset...
January 17, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29341890/periodontal-diseases-and-adverse-pregnancy-outcomes-is-there-a-role-for-vitamin-d
#14
REVIEW
Anne Marie Uwitonze, Peace Uwambaye, Moses Isyagi, Chrispinus H Mumena, Alice Hudder, Afrozul Haq, Kamrun Nessa, Mohammed S Razzaque
Studies have shown a relationship between maternal periodontal diseases (PDs) and premature delivery. PDs are commonly encountered oral diseases which cause progressive damage to the periodontal ligament and alveolar bones, leading to loss of teeth and oral disabilities. PDs also adversely affect general health by worsening cardiovascular and metabolic diseases. Moreover, maternal PDs are thought to be related to increasing the frequency of preterm-birth with low birth weight (PBLBW) new-borns. Prematurity and immaturity are the leading causes of prenatal and infant mortality and is a major public health problem around the world...
January 13, 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29341044/antenatal-medical-therapies-to-improve-lung-development-in-congenital-diaphragmatic-hernia
#15
Aidan Kashyap, Philip DeKoninck, Kelly Crossley, Marta Thio, Graeme Polglase, Francesca Maria Russo, Jan Deprest, Stuart Hooper, Ryan Hodges
Congenital diaphragmatic hernia (CDH) is a birth defect characterized by failed closure of the diaphragm, allowing abdominal viscera to herniate into the thoracic cavity and subsequently impair pulmonary and vascular development. Despite improving standardized postnatal management, there remains a population of severe CDH for whom postnatal care falls short. In these severe cases, antenatal surgical intervention (fetoscopic endoluminal tracheal occlusion [FETO]) may improve survival; however, FETO increases the risk of preterm delivery, is not widely offered, and still fails in half of cases...
January 16, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29339829/associations-of-the-dietary-approaches-to-stop-hypertension-dash-diet-with-pregnancy-complications-in-project-viva
#16
Aarohee P Fulay, Sheryl L Rifas-Shiman, Emily Oken, Wei Perng
BACKGROUND/OBJECTIVES: The Dietary Approaches to Stop Hypertension (DASH) diet has been shown to improve cardiometabolic outcomes in non-pregnant populations. Little is known regarding the impact of this diet on health during pregnancy. The objective of this research is to examine associations of adherence to the DASH diet with hypertensive disorders of pregnancy (HDP) and other pregnancy outcomes. SUBJECTS/METHODS: We conducted analyses with data that came from 1760 women in Project Viva, a Boston-area longitudinal cohort recruited in early pregnancy 1999-2002...
January 17, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29339463/cell-cycle-arrest-and-apoptosis-induced-by-porphyromonas-gingivalis-requires-jnk-and-p53-mediated-p38-activation-in-human-trophoblasts
#17
Hiroaki Inaba, Atsuo Amano, Richard J Lamont, Yukitaka Murakami, Michiyo Matsumoto-Nakano
Porphyromonas gingivalis, a periodontal pathogen, has been implicated as a causative agent of preterm delivery of low-birth-weight infants. We previously reported that P. gingivalis activated cellular DNA damage signaling pathways and ERK1/2 that lead to G1 arrest and apoptosis in extravillous trophoblast cells (HTR-8 cells) derived from the human placenta. In the present study, we further examined alternative signaling pathways mediating cellular damage caused by P. gingivalis. P. gingivalis infection of HTR-8 cells induced phosphorylation of p38 and JNK, while their inhibitors diminished both G1 arrest and apoptosis...
January 16, 2018: Infection and Immunity
https://www.readbyqxmd.com/read/29338857/obstetric-complications-after-frozen-versus-fresh-embryo-transfer-in-women-with-polycystic-ovary-syndrome-results-from-a-randomized-trial
#18
Bo Zhang, Daimin Wei, Richard S Legro, Yuhua Shi, Jing Li, Lin Zhang, Yan Hong, Gang Sun, Ting Zhang, Weiping Li, Zi-Jiang Chen
OBJECTIVE: To evaluate the effect of frozen embryo transfer on maternal and neonatal complications of singleton and twin pregnancies compared with fresh embryo transfer in women with polycystic ovary syndrome (PCOS). DESIGN: A secondary analysis of a multicenter, randomized, controlled trial comparing live birth after frozen vs. fresh embryo transfer (FreFro-PCOS). SETTING: Reproductive medicine centers. PATIENT(S): A total of 1,508 patients with a diagnosis of PCOS who were undergoing IVF were enrolled...
January 12, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29337448/-obstetrics
#19
Véronique Othenin-Girard, Noémie Bouchet, Riccardo E Pfister, Olivier Baud, Nicole Jastrow, Agnès Ditisheim, Nadia Berkane, Begoña Martinez De Tejada
During the past year, we have renewed interest in old well-known problems. New studies and guidelines have been issued about lung maturation in cases of preterm delivery after 37 weeks of gestation. Short term benefits have been proven but the number of cases needed to treat to prevent one case of respiratory complications is high and with possible neurological long-term effects. Also, several studies have shown the benefits of including the ultrasound measurement of the inferior segment of the uterus in order to attempt vaginal delivery after caesarean section with the lowest risk for uterine rupture, while others studies have shown the best procedure to close the uterus during cesarean section...
January 10, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29336477/intraoperative-adverse-events-associated-with-extremely-preterm-cesarean-deliveries
#20
Charline Bertholdt, Sophie Menard, Pierre Delorme, Marie-Charlotte Lamau, François Goffinet, Camille Le Ray
INTRODUCTION: At the same time as survival is increasing among premature babies born before 26 weeks of gestation, the rates of cesarean deliveries before 26 weeks is also rising. Our purpose was to compare the frequency of intraoperative adverse events during cesarean deliveries at two gestational age groups: 24-25 weeks and 26-27 weeks. MATERIAL AND METHODS: This single-center retrospective cohort study included all women with cesarean deliveries performed before 28+0 weeks from 2007 through 2015...
January 16, 2018: Acta Obstetricia et Gynecologica Scandinavica
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