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https://www.readbyqxmd.com/read/28944318/intereye-agreement-of-retinopathy-of-prematurity-from-image-evaluation-in-the-telemedicine-approaches-to-evaluating-of-acute-phase-rop-e-rop-study
#1
Gui-Shuang Ying, Wei Pan, Graham E Quinn, Ebenezer Daniel, Michael X Repka, Agnieshka Baumritter
PURPOSE: To determine the symmetry on retinal image grading of fellow eyes for retinopathy of prematurity (ROP) features (stage, zone and plus disease) and severity, to provide the basis for the within subject comparison for ROP trials. DESIGN: Secondary analyses of data from the Telemedicine Approaches to Evaluating of Acute-Phase ROP (e-ROP) Study. SUBJECTS: Infants with birth weight less than 1251g. METHODS: Infants underwent serial retinal imaging sessions in both eyes by certified imagers starting at 32-weeks postmenstrual age (PMA)...
July 2017: Ophthalmology retina
https://www.readbyqxmd.com/read/28943321/a-randomized-pilot-study-comparing-the-role-of-peep-o2-flow-and-high-flow-air-for-weaning-of-ventilatory-support-in-very-low-birth-weight-infants
#2
Chang-Yo Yang, Mei-Chin Yang, Shih-Ming Chu, Ming-Chou Chiang, Reyin Lien
BACKGROUND: There is a lack of evidence to guide step-wise weaning of positive pressure respiratory support for premature infants. This study sought to compare the efficacy of three weaning protocols we designed to facilitate weaning of very low birth weight (VLBW, less than 1500 g) preterm infants from nasal continuous positive airway pressure (NCPAP) support. METHODS: This was a prospective, randomized, controlled trial of VLBW preterm infants who received positive pressure ventilatory support in our neonatal intensive care unit (NICU) from April 2008 through March 2009...
September 6, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28943081/a-large-retrospective-review-of-persistent-proteinuria-in-children
#3
Chingying Chang-Chien, Gwo-Tsann Chuang, I-Jung Tsai, Bor-Luen Chiang, Yao-Hsu Yang
BACKGROUND: Proteinuria is a common finding in children. It may be due to a benign cause, but it can also represent early renal injury. Of children with persistent proteinuria noted in mass urine screening programs, 35% have a urine protein level greater than 100 mg/dl and many of them are associated with many underlying renal diseases. The aim of this study was to identify the etiology and prognosis of persistent proteinuria in children. METHODS: We collected data on urine protein from January 2011 to December 2016 in a tertiary medical center...
September 21, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28942689/fetal-inflammatory-response-syndrome-firs-and-outcome-of-preterm-neonates-%C3%A2-a-prospective-analytical-study
#4
Francis, Vishnu Bhat, Nivedita Mondal, Bethou Adhisivam, Sajini Jacob, Gowri Dorairajan, Bn Harish
OBJECTIVES: To estimate the incidence of fetal inflammatory response syndrome (FIRS) in preterm neonates and correlate it with immediate and 1-year neurodevelopmental outcome. MATERIAL AND METHODS: This prospective observational analytical study, in preterm neonates with gestational age between 26 and 34 weeks was conducted from May 2014 to December 2015 in a tertiary care hospital in South India. FIRS was defined as the presence of either elevated levels of interleukin-6 (IL-6) in cord blood ≥ 11 pg/ml and / or the placental histopathology showing evidence of fetal inflammatory response...
September 24, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28942545/factors-influencing-piglet-pre-weaning-mortality-in-47-commercial-swine-herds-in-thailand
#5
Morakot Nuntapaitoon, Padet Tummaruk
The present study aims to determine the occurrence of piglet pre-weaning mortality in commercial swine herds in Thailand in relation to piglet, sow, and environmental factors. Data were collected from the database of the computerized recording system from 47 commercial swine herds in Thailand. The raw data were carefully scrutinized for accuracy. Litters with a lactation length < 16 days or >28 days were excluded. In total, 199,918 litters from 74,088 sows were included in the analyses. Piglet pre-weaning mortality at the individual sow level was calculated as piglet pre-weaning mortality (%) = (number of littermate pigs - number of piglets at weaning) / number of littermate pigs...
September 24, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28942447/anogenital-distance-in-term-newborns-in-kumasi-ghana
#6
Serwah Bonsu Asafo-Agyei, Emmanuel Ameyaw, Jean-Pierre Chanoine, Margaret Zacharin, Samuel Blay Nguah, Olumide Olatokunbo Jarrett
BACKGROUND: Anogenital distance (AGD) is a simple noninvasive measure of foetal androgen exposure. This study was done to generate normative data on AGD in Ghanaian newborns. METHODS: AGD was measured in 644 male and 612 female term newborns; including the distance between the anterior base of the penis and the centre of the anus, the posterior base of the penis and the centre of the anus, and the posterior base of the scrotum and the centre of the anus (ASD) in males and the distance from the anus to the fourchette (AF) and from the anus to the base of the clitoris in females...
September 22, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28942446/status-of-vitamin-a-and-related-compounds-and-clinical-outcomes-in-maternal-infant-pairs-in-the-midwestern-united-states
#7
Corrine Hanson, Marina Schumacher, Elizabeth Lyden, Jeremy Furtado, Matthew Van Ormer, Elizabeth McGinn, Katherine Rilett, Caleb Cave, Rebecca Johnson, Kara Weishaar, Ann Anderson-Berry
BACKGROUND: Vitamin A is an essential nutrient for pregnant women, and other vitamin A-related compounds, including lutein and lycopene, have been associated with maternal-infant outcomes. The objective of this study was to quantify the status of vitamin A and related compounds in maternal-infant pairs at the time of delivery, and to determine its impact on clinical outcomes. METHODS: Maternal and cord blood samples were collected in 189 mother-infant pairs. Concentrations of lutein + zeaxanthin, β-cryptoxanthin, lycopene, carotenes, and retinol were measured using high-performance liquid chromatography...
September 22, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28942206/racial-residential-segregation-and-adverse-birth-outcomes-a%C3%A2-systematic-review-and-meta-analysis
#8
REVIEW
Renee Mehra, Lisa M Boyd, Jeannette R Ickovics
RATIONALE: Persistent racial disparities in adverse birth outcomes are not fully explained by individual-level risk factors. Racial residential segregation-degree to which two or more groups live apart from one another-may contribute to the etiology of these birth outcome disparities. Our aim was to assess associations between segregation and adverse birth outcomes by race. This review focused on formal measures of segregation, using Massey and Denton's framework (1998) that identifies five distinct operationalizations of segregation, in addition to proxy measures of segregation such as racial composition, in order to gain a deeper understanding of the operationalizations of segregation most salient for birth outcomes...
September 11, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28942045/higher-risk-of-preterm-birth-and-low-birth-weight-following-oocyte-donation-a-systematic-review-and-meta-analysis
#9
REVIEW
Mariano Mascarenhas, Sesh Kamal Sunkara, Belavendra Antonisamy, Mohan S Kamath
OBJECTIVES: To perform a systematic review and meta-analysis of the known literature to assess whether the perinatal outcomes are different after oocyte donation (OD) compared to autologous oocyte (AO) in vitro fertilization (IVF) pregnancies. STUDY DESIGN: A systematic literature search was done for studies published in English from 1980 to 2016. Studies comparing perinatal outcomes of pregnancies following fresh or frozen OD and AO IVF were included. Meta-analysis was performed using the Rev Man 5...
September 19, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28941930/cannulating-the-contraindicated-effect-of-low-birth-weight-on-mortality-in-neonates-with-congenital-diaphragmatic-hernia-on-extracorporeal-membrane-oxygenation
#10
Patrick T Delaplain, Lishi Zhang, Yanjun Chen, Danh V Nguyen, Matteo Di Nardo, John Patrick Cleary, Peter T Yu, Yigit S Guner
BACKGROUND/PURPOSE: Restrictions for ECMO in neonates include birth weight less than 2kg (BW <2kg) and/or gestational age less than 34weeks (GA <34weeks). We sought to describe their relationship on mortality. METHODS: Neonates with a primary diagnosis code of CDH were identified in the Extracorporeal Life Support Organization (ELSO) registry, and logistic regression models were used to examine the effect of BW <2kg and GA <34weeks on mortality. RESULTS: We identified 7564 neonates with CDH...
September 2, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28940481/prevention-of-preterm-birth-with-pessary-in-singletons-popps-a-randomized-controlled-trial
#11
Lorraine Dugoff, Vincenzo Berghella, Harish Sehdev, A Dhanya Mackeen, Laura Goetzl, Jack Ludmir
OBJECTIVE: To determine if pessary use prevents preterm birth in singleton gestations with a short transvaginal ultrasound cervical length and without a prior spontaneous preterm birth. METHODS: In this open-label multicenter randomized trial we enrolled asymptomatic women with singleton gestations with a transvaginal ultrasound cervical length ≤ 25 mm at 18(0) -23(6) weeks and no prior spontaneous preterm birth. Subjects were randomized to receive the Bioteque cup pessary or no pessary...
September 20, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28939424/maternal-early-pregnancy-vitamin-d-status-in-relation-to-low-birth-weight-and-small-for-gestational-age-offspring
#12
Huiping Wang, Yanfeng Xiao, Lan Zhang, Qiong Gao
Maternal vitamin D deficiency is an independent risk factor for fetal growth. We examined the associations between maternal vitamin D status (defined by 25-hydroxyvitamin D [25(OH)D]) at the first prenatal visit and measures of newborn and placental weight, in a large China cohort of singleton, term, live births. From July 2015 to June 2016, women delivering singleton, term, live births with 25(OH)D measured at a first prenatal visit (N=747). Birth weight, placental weight, the placental to fetal weight ratio, and small for gestational age (SGA) were measured...
September 19, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28939183/urinary-phthalate-metabolite-concentrations-and-maternal-weight-during-early-pregnancy
#13
Andrea Bellavia, Russ Hauser, Ellen W Seely, John D Meeker, Kelly K Ferguson, Thomas F McElrath, Tamarra James-Todd
BACKGROUND: Phthalates are a class of chemicals that may be associated with obesity in non-pregnant populations. Little is known about the association between pregnancy phthalate exposure and maternal obesity. OBJECTIVE: We evaluated the association between early-pregnancy urinary concentrations of specific phthalate metabolites and the distribution of body mass index (BMI, cross-sectional), and early gestational weight gain (GWG, prospective). METHODS: We measured 1st trimester urinary phthalate metabolite concentrations (median 9...
September 12, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28938735/the-age-of-fathers-in-the-usa-is-rising-an-analysis-of-168-867-480-births-from-1972-to-2015
#14
Yash S Khandwala, Chiyuan A Zhang, Ying Lu, Michael L Eisenberg
STUDY QUESTION: How has the mean paternal age in the USA changed over the past 4 decades? SUMMARY ANSWER: The age at which men are fathering children in the USA has been increasing over time, although it varies by race, geographic region and paternal education level. WHAT IS KNOWN ALREADY: While the rise in mean maternal age and its implications for fertility, birth outcomes and public health have been well documented, little is known about paternal characteristics of births within the USA...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28938431/association-of-thyroid-function-with-maternal-and-neonatal-homocysteine-concentrations
#15
Mirjana Barjaktarovic, Eric A P Steegers, Vincent W V Jaddoe, Yolanda B de Rijke, Theo J Visser, Tim I M Korevaar, Robin P Peeters
Context: High homocysteine concentrations are associated with maternal pregnancy complications and low birth weight, jaundice and cerebrovascular accidents in neonates. Thyroid hormone may interfere with homocysteine metabolism via stimulation of vitamin B12- and folate-dependent processes and via effects on enzymes of the re-methylation pathway. Objective: Investigating the associations of maternal and neonatal thyroid function with homocysteine during pregnancy and after delivery, respectively...
September 5, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28938413/prenatal-diagnosis-of-resistance-to-thyroid-hormone-and-its-clinical-implications
#16
Theodora Pappa, João Anselmo, Sunnee Mamanasiri, Alexandra M Dumitrescu, Roy E Weiss, Samuel Refetoff
Context: Resistance to thyroid hormone beta (RTHβ) is an autosomal dominant disorder characterized by reduced sensitivity of target tissues to thyroid hormones (TH). Individuals with RTHβ have high TH levels usually due to mutations in the TH receptor beta (THRB) gene. The management of RTHβ during pregnancy is challenging as wild-type (WT) fetuses born to RTHβ mothers have low birth weight and suppressed postnatal TSH, due to intrauterine exposure to excess TH. Objective: To determine birth weight and postnatal TSH of WT fetuses carried by mothers with RTHβ whose fT4 levels were maintained below 20% the upper limit of normal (ULN)...
August 4, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28938051/pregnancy-disorders-in-africa-and-the-obstetric-dilemma
#17
Annettee Nakimuli, Ashley Moffett
The high neonatal and maternal morbidity and mortality associated with the extremes of birth weight is referred to as the obstetric dilemma. Pre-eclampsia and other conditions that lead to low birth weight are considered as the Great Obstetrical Syndromes (GOS). At the other extreme is high birth weight resulting in obstructed labour. Fetal weight largely depends on placental function and defective placentation is a common feature of the GOS. There is evidence that the local uterine immune system (KIR and HLA-C) regulates placentation, with racial differences noted...
December 1, 2016: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28937572/obstetric-care-consensus-no-6-periviable-birth
#18
(no author information available yet)
Approximately 0.5% of all births occur before the third trimester of pregnancy, and these very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. A recent executive summary of proceedings from a joint workshop defined periviable birth as delivery occurring from 20 0/7 weeks to 25 6/7 weeks of gestation. When delivery is anticipated near the limit of viability, families and health care teams are faced with complex and ethically challenging decisions. Multiple factors have been found to be associated with short-term and long-term outcomes of periviable births in addition to gestational age at birth...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28937567/obstetric-care-consensus-no-6-summary-periviable-birth
#19
(no author information available yet)
Approximately 0.5% of all births occur before the third trimester of pregnancy, and these very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. A recent executive summary of proceedings from a joint workshop defined periviable birth as delivery occurring from 20 0/7 weeks to 25 6/7 weeks of gestation. When delivery is anticipated near the limit of viability, families and health care teams are faced with complex and ethically challenging decisions. Multiple factors have been found to be associated with short-term and long-term outcomes of periviable births in addition to gestational age at birth...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28937240/baroreflex-sensitivity-in-premature-infants-relation-to-the-parameters-characterizing-intrauterine-and-postnatal-condition
#20
K Haskova, M Javorka, B Czippelova, M Zibolen, K Javorka
At present, there are insufficient information about baroreflex sensitivity (BRS) and factors that determine BRS in premature newborns. The objective of this study was to determine the relationship between BRS and the characteristics that reflecting the intrauterine development (gestational age and birth weight), as well as postnatal development (postconception age and the actual weight of the child at the time of measurement). We examined 57 premature infants, who were divided into groups according to gestational age and postconception age as well as birth weight, and weight at the time of measurement...
September 22, 2017: Physiological Research
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