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https://www.readbyqxmd.com/read/29166302/hierarchical-semi-bayes-methods-for-misclassification-in-perinatal-epidemiology
#1
Richard F MacLehose, Lisa M Bodnar, Craig Meyer, Haitao Chu, Timothy L Lash
BACKGROUND: Validation data are used to estimate the extent of misclassification in epidemiologic studies. In the Penn MOMS cohort, prepregnancy BMI is subject to misclassification and validation data are available to estimate the extent of misclassification. We use these data to estimate the association between maternal prepregnancy body mass index and early preterm (<32 weeks) birth using a semi-Bayes hierarchical model allowing for more flexible adjustment for misclassification...
November 18, 2017: Epidemiology
https://www.readbyqxmd.com/read/29166190/comparison-of-various-kangaroo-mother-care-carriers-on-maternal-comfort-a-pilot-study
#2
Sholihatul Amaliya, Yeni Rustina, Nur Agustini
Kangaroo mother care (KMC) is an evidence-based approach that has been scientifically proven to have a positive effect on mothers and infants. One of the barriers to performing KMC at home is the absence of a special KMC carrier. The most widely used KMC carriers in Indonesia are kangaroo pouch, thari, wrap and traditional wraps in the form of a long strip of fabric. This study's aim was to compare the level of maternal comfort when performing KMC with three different KMC carriers. The study used crossover design involving 20 mothers with low birth weight (LBW) infants as responders, selected through a consecutive sampling method...
2017: Compr Child Adolesc Nurs
https://www.readbyqxmd.com/read/29166182/increasing-confidence-and-ability-in-implementing-kangaroo-mother-care-method-among-young-mothers
#3
Eleni Kenanga Purbasary, Yeni Rustina, Tri Budiarti
Mothers giving birth to low birth weight babies (LBWBs) have low confidence in caring for their babies because they are often still young and may lack the knowledge, experience, and ability to care for the baby. This research aims to determine the effect of education about kangaroo mother care (KMC) on the confidence and ability of young mothers to implement KMC. The research methodology used was a controlled-random experimental approach with pre- and post-test equivalent groups of 13 mothers and their LBWBs in the intervention group and 13 mothers and their LBWBs in the control group...
2017: Compr Child Adolesc Nurs
https://www.readbyqxmd.com/read/29165697/lifting-and-pregnancy-outcomes-feasibility-of-a-randomized-controlled-trial
#4
E Kwegyir-Afful, J Verbeek, L Aziato, J D Seffah, K Vehviläinen-Julkunen, K Räsänen
Background: The highest incidence of preterm birth (18%) occurs in Africa but the causes are largely unknown. Some studies have reported adverse effects of maternal physical exertion on birth outcomes. A randomized controlled trial (RCT) is proposed to determine the effectiveness of an intervention reducing lifting and carrying in pregnant women in reducing preterm birth and low birthweight. Aims: To test the feasibility and acceptability of the proposed lift-less intervention RCT...
November 19, 2017: Occupational Medicine
https://www.readbyqxmd.com/read/29165598/fetal-growth-and-birth-anthropometrics-in-metformin-exposed-offspring-born-to-mothers-with-pcos
#5
Anna Hjorth-Hansen, Øyvind Salvesen, Liv Guro Engen Hanem, Torbjørn Eggebø, Kjell Å Salvesen, Eszter Vanky, Rønnaug Ødegård
Context: Metformin is used in attempt to reduce pregnancy complications associated with polycystic ovary syndrome (PCOS). Little is known about the metformin impact on fetal development and growth. Objectives: Exploring the metformin effect vs. placebo on fetal growth and birth anthropometrics in PCOS-offspring compared to a reference population in relation to maternal BMI. Design: Post-hoc analysis of an RCT. Setting: Double-blind, placebo-controlled, multicenter study...
November 17, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29165579/investigating-mediators-of-the-poor-pneumonia-outcomes-of-human-immunodeficiency-virus-exposed-but-uninfected-children
#6
Matthew S Kelly, Jiayin Zheng, Sefelani Boiditswe, Andrew P Steenhoff, Kristen A Feemster, Tonya Arscott-Mills, Boitshepe Seme, Bakgaki Ratshaa, Ikanyeng Rulaganyang, Mohamed Z Patel, Savarra Mantzor, Samir S Shah, Coleen K Cunningham
Background: Human immunodeficiency virus-exposed but uninfected (HIV-EU) children have a higher mortality rate than the children of HIV-negative mothers (HIV-unexposed). Causal mediators of the poor health outcomes of HIV-EU children remain poorly defined. Methods: We conducted a hospital-based prospective cohort study of children aged 1 to 23 months with clinically defined pneumonia. The children were recruited at a referral hospital in Gaborone, Botswana, between April 2012 and June 2016...
November 20, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29165555/prenatal-exposure-to-di-2-ethylhexyl-phthalate-dehp-disrupts-ovarian-function-in-a-transgenerational-manner-in-female-mice
#7
Saniya Rattan, Emily Brehm, Liying Gao, Sarah Niermann, Jodi A Flaws
Di(2-ethylhexyl) phthalate (DEHP) is a plasticizer found in polyvinyl chloride products such as vinyl flooring, plastic food containers, medical devices, and children's toys. DEHP is a ubiquitous environmental contaminant and is a known endocrine disrupting chemical. Little is known about the effects of prenatal DEHP exposure on the ovary and whether effects occur in subsequent generations. Thus, we tested the hypothesis that prenatal exposure to DEHP disrupts ovarian functions in the F1, F2, and F3 generations of female mice...
November 20, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29165513/-a-five-year-experience-with-zoonotic-salmonella-at-a-pediatric-reference-centre
#8
Patricia Barrios, Federica Badía, Valentina Misa, M Inés Mota, Arací Martínez, Hebert Mariño, Gabriela Algorta, Javier Prego, M Catalina Pírez
BACKGROUND: Salmonella can cause asymptomatic infections, diarrhea, bacteremia and focal infections such as meningitis and osteomyelitis. AIM: To describe clinical and microbiological aspects of infections by Salmonella spp. in children in a pediatric referral hospital: Centro Hospitalario Pereira Rossell, in Montevideo, Uruguay. MATERIALS AND METHODS: Descriptive and retrospective study of 46 patients, from which Salmonella spp was isolated between January 1, 2005 and December 31, 2010...
August 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29165157/the-hokkaido-birth-cohort-study-on-environment-and-children-s-health-cohort-profile-updated-2017
#9
Reiko Kishi, Atsuko Araki, Machiko Minatoya, Tomoyuki Hanaoka, Chihiro Miyashita, Sachiko Itoh, Sumitaka Kobayashi, Yu Ait Bamai, Keiko Yamazaki, Ryu Miura, Naomi Tamura, Kumiko Ito, Houman Goudarzi
The Hokkaido Study on Environment and Children's Health is an ongoing study consisting of two birth cohorts of different population sizes: the Sapporo cohort and the Hokkaido cohort. Our primary study goals are (1) to examine the effects of low-level environmental chemical exposures on birth outcomes, including birth defects and growth retardation; (2) to follow the development of allergies, infectious diseases, and neurobehavioral developmental disorders and perform a longitudinal observation of child development; (3) to identify high-risk groups based on genetic susceptibility to environmental chemicals; and (4) to identify the additive effects of various chemicals, including tobacco smoking...
May 18, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29165149/association-of-excessive-mobile-phone-use-during-pregnancy-with-birth-weight-an-adjunct-study-in-kumamoto-of-japan-environment-and-children-s-study
#10
Xi Lu, Masako Oda, Takashi Ohba, Hiroshi Mitsubuchi, Shota Masuda, Takahiko Katoh
BACKGROUND: Low birth weight has been shown to be closely associated with neonatal mortality and morbidity, inhibited growth, poor cognitive development, and chronic diseases later in life. Some studies have also shown that excessive mobile phone use in the postnatal period may lead to behavioral complications in the children during their growing years; however, the relationship between mobile phone use during pregnancy and neonatal birth weight is not clear. The aim of the present study was to determine the associations of excessive mobile phone use with neonatal birth weight and infant health status...
June 8, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29165138/a-relationship-between-a-level-of-hemoglobin-after-delivery-and-exclusive-breastfeeding-initiation-at-a-baby-friendly-hospital-in-japan
#11
Saki Horie, Kyoko Nomura, Shinichi Takenoshita, Junko Nakagawa, Michiko Kido, Mitsuhiro Sugimoto
BACKGROUND: The recent National Nutrition Survey of 2013 demonstrated that 16.7% of women in childbearing age are underweight, and 5.0-10.0% of these women manifested a Hemoglobin (Hb) level less than 11.0 g/dl. The purpose of this study was to investigate if such maternal nutritional status affects success of exclusive breastfeeding (EBF) practice. METHODS: This cross-sectional study investigated 1532 dyads of mothers and infants with full-term singleton pregnancies delivered during 2011 at a perinatal center in Tokyo...
April 20, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29165117/effects-of-intrauterine-exposures-to-polychlorinated-biphenyls-methylmercury-and-lead-on-birth-weight-in-japanese-male-and-female-newborns
#12
Nozomi Tatsuta, Naoyuki Kurokawa, Kunihiko Nakai, Keita Suzuki, Miyuki Iwai-Shimada, Katsuyuki Murata, Hiroshi Satoh
BACKGROUND: The effects of prenatal exposures to polychlorinated biphenyls (PCBs), methylmercury, and lead on birth weight remain disputable. The aim of this study was to investigate whether these chemicals affect birth weight of Japanese newborns, with special emphasis on determining whether these effects differ between males and females. METHODS: The subjects from Tohoku Study of Child Development, which was designed to examine the developmental effects of prenatal exposures to such hazardous chemicals, were 489 mother-newborn pairs with complete data including smoking habit during pregnancy...
April 12, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29164953/unintended-birth-and-children-s-long-term-mental-health
#13
Jessica Houston Su
Research has examined the proximate effects of unintended birth on infants and young children, but we know relatively little about the longer-term effects. Given that unintended birth is associated with several childhood risk factors, it might set the stage for poor mental health in adulthood. Drawing on rich intergenerational survey data from the National Longitudinal Survey of Youth, 1979 ( N = 3,742), this study used a variety of statistical techniques to examine whether maternal pregnancy intentions are associated with children's depressive symptoms during early adulthood...
September 2017: Journal of Health and Social Behavior
https://www.readbyqxmd.com/read/29164515/early-life-exposure-to-cadmium-triggers-distinct-zn-dependent-protein-expression-patterns-and-impairs-brain-development
#14
Safa Ben Mimouna, Marouane Chemek, Sana Boughammoura, Mohamed Banni, Imed Messaoudi
The objective of this study was to determine if the brain development impairment induced by early-life exposure to cadmium (Cd) could result from changes in the expression pattern of distinct zinc (Zn)-dependent proteins. For this purpose, adult female rats receiving either tap water, Cd, Zn, or Cd + Zn in their drinking water during gestation and lactation periods were used. After birth, the male offspring were screened for locomotors and sensorial defects. At postnatal day 21 (PND 21), the male pups were sacrificed and their brains, liver, and plasma were taken for chemical, biochemical, and molecular analyses...
November 22, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/29164087/plasma-brain-derived-neurotrophic-factor-levels-in-newborn-infants-with-neonatal-abstinence-syndrome
#15
Lochan Subedi, Hong Huang, Amrita Pant, Philip M Westgate, Henrietta S Bada, John A Bauer, Peter J Giannone, Thitinart Sithisarn
Background: Brain-derived neurotrophic factor (BDNF) is a type of growth factor that promotes growth and survival of neurons. Fetal exposure to opiates can lead to postnatal withdrawal syndrome, which is referred as neonatal abstinence syndrome (NAS). Preclinical and clinical studies have shown an association between opiates exposure and alteration in BDNF expression in the brain and serum levels in adult. However, to date, there are no data available on the effects of opiate exposure on BDNF levels in infant who are exposed to opiates in utero and whether BDNF level may correlate with the severity of NAS...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29163989/axial-length-and-ocular-development-of-premature-infants-without-rop
#16
Yi Zha, Guangdong Zhu, Jinfei Zhuang, Haihua Zheng, Jianqiu Cai, Wangqiang Feng
Purpose: To investigate the ocular parameters of premature infants without ROP at gestational age (GA) more than 28 weeks and their relationship with growth parameters. Methods: 76 preterm infants without ROP and 65 term infants were involved to undergo portable slit lamp, RetCam3, ultrasonic A-scan biometry, and cycloplegic streak examination at their 40 weeks' postconceptional ages (PCA). Ocular parameters of infants' right eye and growth parameters were used for analysis...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29163937/development-and-validation-of-a-simplified-algorithm-for-neonatal-gestational-age-assessment-protocol-for-the-alliance-for-maternal-newborn-health-improvement-amanhi-prospective-cohort-study
#17
Abdullah Baqui, Parvez Ahmed, Sushil Kanta Dasgupta, Nazma Begum, Mahmoodur Rahman, Nasreen Islam, Mohammad Quaiyum, Betty Kirkwood, Karen Edmond, Caitlin Shannon, Samuel Newton, Lisa Hurt, Fyezah Jehan, Imran Nisar, Atiya Hussain, Naila Nadeem, Muhammad Ilyas, Anita Zaidi, Sunil Sazawal, Saikat Deb, Arup Dutta, Usha Dhingra, Said Moh'd Ali, Davidson H Hamer, Katherine Ea Semrau, Marina Straszak-Suri, Caroline Grogan, Godfrey Bemba, Anne Cc Lee, Blair J Wylie, Alexander Manu, Sachiyo Yoshida, Rajiv Bahl
Objective: The objective of the Alliance for Maternal and Newborn Health Improvement (AMANHI) gestational age study is to develop and validate a programmatically feasible and simple approach to accurately assess gestational age of babies after they are born. The study will provide accurate, population-based rates of preterm birth in different settings and quantify the risks of neonatal mortality and morbidity by gestational age and birth weight in five South Asian and sub-Saharan African sites...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29163369/preconception-prebiotic-and-sitagliptin-treatment-in-obese-rats-affects-pregnancy-outcomes-and-offspring-microbiota-adiposity-and-glycemia
#18
Carol A Dennison, Amanda J Eslinger, Raylene A Reimer
Maternal obesity is associated with increased risk of pregnancy complications and greater risk of obesity in offspring, but studies designed to examine preconception weight loss are limited. The objective of this study was to determine if a combined dietary [oligofructose (OFS)] and pharmacological (sitagliptin) preconception intervention could mitigate poor pregnancy outcomes associated with maternal obesity and improve offspring metabolic health and gut microbiota composition. Diet-induced obese female Sprague-Dawley rats were randomized to one of four intervention groups for 8 weeks: (1) Obese-Control (consumed control diet during intervention); (2) Obese-OFS (10% OFS diet); (3) Obese-S (sitagliptin drug); (4) Obese-OFS + S (combination treatment)...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29162952/oral-health-status-and-fertility-treatment-including-ivf
#19
REVIEW
Sunali Sundeep Khanna, Prita A Dhaimade, Shalini Malhotra
Oral health is extremely important for the general wellbeing of the individual. From a number of research articles, it is established that there is a definitive connection between periodontal health and many systemic diseases, like type II diabetes, cardiovascular diseases and even preterm labor and low birth weight of babies. The significant rate of failure in the treatment of infertility and IVF (in vitro fertilization) even with multiple advancements in the last decade has made scientist take interest in newer parameters of health, an important one among them being periodontal health...
December 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29162873/rapid-in-situ-imaging-and-whole-genome-sequencing-of-biofilm-in-neonatal-feeding-tubes-a-clinical-proof-of-concept
#20
Pauline Ogrodzki, Chi Shing Cheung, Mohamed Saad, Khaled Dahmani, Rebecca Coxill, Haida Liang, Stephen J Forsythe
The bacterial flora of nasogastric feeding tubes and faecal samples were analysed for a low-birth weight (725 g) neonate EGA 25 weeks in intensive care. Samples were collected at age 6 and 8 weeks of life. Optical coherence tomography (OCT) was used to visualise bacterial biofilms inside the nasogastric feeding tubes. The biofilm was heterogeneously distributed along the tube lumen wall, and had a depth of up to 500 µm. The bacterial biofilm and faecal samples included Enterococcus faecalis and Enterobacter hormaechei...
November 21, 2017: Scientific Reports
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