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https://www.readbyqxmd.com/read/29224193/screening-of-yeasts-for-the-production-of-2-phenylethanol-rose-aroma-in-organic-waste-based-media
#1
Chreptowicz Karolina, Sternicka Magdalena Katarzyna, Kowalska Patrycja Daria, Mierzejewska Jolanta
In the present study, we isolated twenty eight yeast strains from samples of plant material and fermented food and evaluated the possibility of efficient production of 2-phenylethanol (2-PE) in the organic waste-based media supplemented with L-phenylalanine (L-Phe). We used whey, a by-product from milk processing, as a base for media and either glucose or three by-products from sugar-beet processing as a fermentable carbon source. Ten newly isolated yeast strains were capable of producing over 2 g l-1 2-PE through the L-Phe biotransformation in a batch-mode in standard medium...
December 9, 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/29223966/advancing-point-of-care-diagnostics-for-the-control-and-prevention-of-stis-the-way-forward
#2
Igor Toskin, Karel Blondeel, Rosanna W Peeling, Carolyn Deal, James Kiarie
WHO recognises the global impact of sexually transmitted infections (STIs) on global public health and individual sexual and reproductive health and well-being. As a component of the WHO Global Health Sector Strategy for the control and prevention of STIs, there has been a growing recognition of the importance of integrating point-of-care tests (POCTs) into overall strategic planning. The process of integrating STI POCTs, in addition to providing a definitive diagnosis and appropriate treatment in a single visit, also includes innovative delivery options, such as on-site delivery, community-based testing (including screening), as well as self-testing at home after purchase of a test online or over-the-counter...
December 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29223818/application-of-airborne-photogrammetry-for-the-visualisation-and-assessment-of-contamination-migration-arising-from-a-fukushima-waste-storage-facility
#3
D T Connor, P G Martin, N T Smith, L Payne, C Hutton, O D Payton, Y Yamashiki, T B Scott
Airborne systems such as lightweight and highly portable unmanned aerial vehicles (UAVs) are becoming increasingly widespread in both academia and industry - with an ever-increasing range of applications, including (but not limited to), air quality sampling, wildlife monitoring and land-use mapping. In this work, high-resolution airborne photogrammetry obtained using a multi-rotor system operating at low survey altitudes, is combined with ground-based radiation mapping data acquired at an interim storage facility for wastes removed as part of the large-scale Fukushima clean-up program...
December 7, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29223769/obstructive-sleep-apnoea-and-alzheimer-s-disease-in-search-of-shared-pathomechanisms
#4
REVIEW
D Polsek, N Gildeh, D Cash, R Winsky-Sommerer, S C R Williams, F Turkheimer, G D Leschziner, M J Morrell, I Rosenzweig
Alzheimer's disease (AD) is a significant public health concern. The incidence continues to rise, and it is set to be over one million in the UK by 2025. The processes involved in the pathogenesis of AD have been shown to overlap with those found in cognitive decline in patients with Obstructive Sleep Apnoea (OSA). Currently, the standard treatment for OSA is Continuous Positive Airway Pressure. Adherence to treatment can, however, be an issue, especially in patients with dementia. Also, not all patients respond adequately, necessitating the use of additional treatments...
December 6, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29223740/statistical-models-for-brain-signals-with-properties-that-evolve-across-trials
#5
REVIEW
Hernando Ombao, Mark Fiecas, Chee-Ming Ting, Yin Fen Low
Most neuroscience cognitive experiments involve repeated presentations of various stimuli across several minutes or a few hours. It has been observed that brain responses, even to the same stimulus, evolve over the course of the experiment. These changes in brain activation and connectivity are believed to be associated with learning and/or habituation. In this paper, we present two general approaches to modeling dynamic brain connectivity using electroencephalograms (EEGs) recorded across replicated trials in an experiment...
December 6, 2017: NeuroImage
https://www.readbyqxmd.com/read/29223236/mechanical-outcome-of-accelerated-corneal-crosslinking-evaluated-by%C3%A2-brillouin%C3%A2-microscopy
#6
Joshua N Webb, Johnny P Su, Giuliano Scarcelli
PURPOSE: To quantify corneal mechanical changes induced by corneal crosslinking (CXL) procedures of different ultraviolet-A (UVA) intensity and exposure time using Brillouin microscopy. SETTINGS: University of Maryland, College Park, Maryland, USA. DESIGN: Experimental study. METHODS: Porcine cornea samples were debrided of epithelia and soaked with riboflavin 0.1% solution. Samples were exposed to a standard 5.4 J/cm2 of UVA radiation with varying intensity and exposure time as follows: 3 mW/cm2 for 30...
November 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29223212/how-to-engage-your-team-to-implement-delayed-cord-clamping
#7
Rebecca L Gams, Kimberly K Popp, Julianne Cramer, Thomas N George, Phillip N Rauk, Samantha A Sommerness, Jane A Sublette
This article describes how a health care team changed practice by implementing delayed cord clamping as standard practice. After administration of a survey to assess clinicians' knowledge and to discover barriers to this proposed practice change, members of a multidisciplinary committee used the results to create a guideline for delayed cord clamping and a plan for successful implementation. Integral to embedding and sustaining changes in practice was development of the Delivery Room Brief and Debrief Tool and inclusion of the process into nursing guidelines and the electronic health record...
December 2017: Nursing for Women's Health
https://www.readbyqxmd.com/read/29223054/optimizing-adsorption-of-blue-pigment-from-wastewater-by-nano-porous-modified-na-bentonite-using-spectrophotometry-based-on-response-surface-method
#8
Neshat Moradi, Shiva Salem, Amin Salem
This work highlighted the effective activation of bentonite paste to produce nano-porous powder for removal of cationic dye from wastewater. The effects of activation parameters such as soda and moisture contents, ageing time and temperature were analyzed using response surface methodology (RSM). The significance of independent variables and their interactions were tested by blending the obtained powders with wastewater and then the adsorption was evaluated, spectrophotometrically. The experiments were carried out by preparation of pastes according to response surface methodology and central composite design, which is the standard method, was used to evaluate the effects and interactions of four factors on the treatment efficiency...
December 5, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29223045/investigation-of-antioxidant-ability-of-grape-seeds-extract-to-prevent-oxidatively-induced-dna-damage-by-gas-chromatography-tandem-mass-spectrometry
#9
Önder Aybastıer, Sam Dawbaa, Cevdet Demir
Phenolic compounds have been studied elaborately for their efficacy to improve health and to protect against a wide variety of diseases. Herein this study, different analysis methods were implemented to evaluate the antioxidant properties of catechin and cyanidin using their standard substances and as they found in the grape seeds extracts. Total phenol contents were 107.39±8.94mg GAE/g dw of grape seeds for grape seed extract (GSE) and 218.32±10.66mg GAE/g dw of grape seeds for acid-hydrolyzed grape seed extract (AcGSE)...
December 6, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29222852/free-breathing-whole-heart-3d-cine-magnetic-resonance-imaging-with-prospective-respiratory-motion-compensation
#10
Mehdi H Moghari, Ashita Barthur, Maria E Amaral, Tal Geva, Andrew J Powell
PURPOSE: To develop and validate a new prospective respiratory motion compensation algorithm for free-breathing whole-heart 3D cine steady-state free precession (SSFP) imaging. METHODS: In a 3D cine SSFP sequence, 4 excitations per cardiac cycle are re-purposed to prospectively track heart position. Specifically, their 1D image is reconstructed and routed into the scanner's standard diaphragmatic navigator processing system. If all 4 signals are in end-expiration, cine image data from the entire cardiac cycle is accepted for image reconstruction...
December 8, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29222758/differential-proteomics-based-on-2d-difference-in-gel-electrophoresis-and-tandem-mass-spectrometry-for-the-elucidation-of-biological-processes-in-antibiotic-producer-bacterial-strains
#11
Giuseppe Gallo, Andrea Scaloni
Proteomics based on 2D-Difference In Gel Electrophoresis (2D-DIGE) coupled with mass spectrometry (MS) procedures can be considered a "gold standard" to determine quantitatively and comparatively protein abundances in cell extracts from different biological sources/conditions according to a gel-based approach. In particular, 2D-DIGE is used for protein specie separation, detection, and relative quantification, whenever tandem MS is used to obtain peptide sequence information that is managed according to bioinformatic procedures to identify the differentially represented protein species...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29222728/fetal-electrocardiogram-extraction-and-analysis-using-adaptive-noise-cancellation-and-wavelet-transformation-techniques
#12
P Sutha, V E Jayanthi
Birth defect-related demise is mainly due to congenital heart defects. In the earlier stage of pregnancy, fetus problem can be identified by finding information about the fetus to avoid stillbirths. The gold standard used to monitor the health status of the fetus is by Cardiotachography(CTG), cannot be used for long durations and continuous monitoring. There is a need for continuous and long duration monitoring of fetal ECG signals to study the progressive health status of the fetus using portable devices. The non-invasive method of electrocardiogram recording is one of the best method used to diagnose fetal cardiac problem rather than the invasive methods...
December 8, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/29222621/lifespan-extension-of-caenorhabditis-elegans-by-butyricicoccus-pullicaecorum-and-megasphaera-elsdenii-with-probiotic-potential
#13
Gayeung Kwon, Jiyun Lee, Jong-Ho Koh, Young-Hee Lim
Butyricicoccus pullicaecorum and Megasphaera elsdenii inhabit the human intestine and have probiotic potential. The aim of this study was to evaluate the effects of B. pullicaecorum and M. elsdenii on the lifespan of Caenorhabditis elegans. They significantly (P < 0.05) extended the lifespan of C. elegans compared with Escherichia coli OP50, a standard food for the worm. Analysis of age-related biomarkers such as lipofuscin, body size, and locomotory activity showed that they retarded aging. They all failed to extend the lifespan of daf-12 or dbl-1 loss-of-function C...
December 8, 2017: Current Microbiology
https://www.readbyqxmd.com/read/29222580/-use-of-antibiotics-in-bones-prophylaxis-and-current-treatment-standards
#14
REVIEW
L Frommelt
BACKGROUND: Treatment of bone infection is difficult due the systemic administration of antibiotics, which means that only low concentrations reach the inflamed bone tissue. Loss of bone stock is common in osteomyelitis and device associated infection. Local antibiotics are administered in several ways for prophylactic purposes and also for treatment of bone infection. We intend to show the options and limitations of clinical use of antibiotic-loaded bone grafts. SUITABILITY: Bone grafts are a suitable carrier system for antibiotics...
December 8, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/29222557/accentuate-the-negative-grammatical-errors-during-narrative-production-as-a-clinical-marker-of-central-nervous-system-abnormality-in-school-aged-children-with-fetal-alcohol-spectrum-disorders
#15
John C Thorne
Purpose: The purpose of this study was to examine (a) whether increased grammatical error rates during a standardized narrative task are a more clinically useful marker of central nervous system abnormality in Fetal Alcohol Spectrum Disorders (FASD) than common measures of productivity or grammatical complexity and (b) whether combining the rate of grammatical errors with the rate of cohesive referencing errors can improve utility of a standardized narrative assessment task for FASD diagnosis...
December 8, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29222292/uncoding-the-genetic-heterogeneity-of-myelodysplastic-syndrome
#16
REVIEW
R Coleman Lindsley
Myelodysplastic syndrome (MDS) is a clinically heterogeneous disease characterized by functional impairment of hematopoiesis and abnormal bone marrow morphology. The type and severity of hematopoietic dysfunction in MDS are highly variable, and the kinetics of disease progression are difficult to predict. Genomic studies have shown that MDS is typically driven by a multistep somatic genetic process affecting a core set of genes. By definition, recurrent MDS driver mutations all drive clonal dominance, although they can have stereotyped positions in the clonal hierarchy or patterns of comutation association and exclusivity...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/29222100/diversity-of-lactococcus-lactis-in-undefined-mixed-dairy-starter-cultures-revealed-by-comparative-genome-analyses-and-targeted-amplicon-sequencing-of-epsd
#17
Cyril A Frantzen, Hans Petter Kleppen, Helge Holo
Undefined mesophilic mixed (DL) starter cultures are used in the production of continental cheeses and contain unknown strain mixtures of Lactococcus lactis and leuconostocs. The choice of starter culture affects the taste, aroma and quality of the final product. To gain insight into the diversity of Lactococcus lactis strains in starter cultures, we whole-genome sequenced 95 isolates from three different starter cultures. Pan-genomic analyses, which included 30 publically available complete genomes, grouped the strains into 21 subsp...
December 8, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29221990/molecular-and-cellular-mechanisms-of-chemoresistance-in-pancreatic-cancer
#18
REVIEW
Aleksandra Adamska, Omar Elaskalani, Aikaterini Emmanouilidi, Minkyoung Kim, Norbaini Binti Abdol Razak, Pat Metharom, Marco Falasca
Pancreatic Ductal Adenocarcinoma (PDAC) is one of the most chemoresistant cancers, and current therapies targeting cancer-associated molecular pathways have not given satisfactory results, owing in part to rapid upregulation of alternative compensatory pathways. Most of the available treatments are palliative, focussing on improving the quality of life. At present, available options are surgery, embolization, radiation, chemotherapy, immunotherapy and use of other more targeted drugs. In this review, we describe the cellular and molecular effects of current chemotherapy drugs such as gemcitabine, FOLFIRINOX (5-fluorouracil [5-FU], oxaliplatin, irinotecan, and leucovorin) and ABRAXANE (nab-Paclitaxel), which have shown a survival benefit, although modest, for pancreatic cancer patients...
November 22, 2017: Advances in Biological Regulation
https://www.readbyqxmd.com/read/29221976/modeling-patient-specific-deformable-mitral-valves
#19
REVIEW
Olivia Ginty, John Moore, Terry Peters, Daniel Bainbridge
Medical imaging has advanced enormously over the last few decades, revolutionizing patient diagnostics and care. At the same time, additive manufacturing has emerged as a means of reproducing physical shapes and models previously not possible. In combination, they have given rise to 3-dimensional (3D) modeling, an entirely new technology for physicians. In an era in which 3D imaging has become a standard for aiding in the diagnosis and treatment of cardiac disease, this visualization now can be taken further by bringing the patient's anatomy into physical reality as a model...
September 7, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29221831/processing-of-implicit-versus-explicit-predictive-contextual-information-in-parkinson-s-disease
#20
Ling Li, Pablo Diaz-Brage, Helena Fernandez-Lago, Noa Fogelson
We investigated the effects of implicit versus explicit local contextual processing in Parkinson's disease (PD) using electrophysiological measures. EEG recording blocks consisted of targets preceded by either randomized sequences of standards or by sequences including a predictive sequence signaling the occurrence of a target event. PD patients ("on" medication) and healthy controls performed two sessions: in the first the regularity of the predictive sequence was implicit, while in the second this regularity was made explicit...
December 5, 2017: Neuropsychologia
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