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Spinal manipulation therapy

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https://www.readbyqxmd.com/read/28324697/adverse-events-in-a-chiropractic-spinal-manipulative-therapy-single-blinded-placebo-randomized-controlled-trial-for-migraineurs
#1
Aleksander Chaibi, Jūratė Šaltytė Benth, Peter J Tuchin, Michael Bjørn Russell
BACKGROUND: Unlike pharmacological randomized controlled trials (RCTs), manual-therapy RCTs do not always report adverse events (AEs). The few manual-therapy RCTs that provide information on AEs are frequently without details, such as the type and-, severity of the AE and reason for withdrawal. OBJECTIVE: To prospectively report all AEs in a chiropractic spinal manipulative therapy (CSMT) RCT. DESIGN: A prospective 3-armed, single-blinded, placebo, RCT...
March 14, 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28292267/assignment-of-adverse-event-indexing-terms-in-randomized-clinical-trials-involving-spinal-manipulative-therapy-an-audit-of-records-in-medline-and-embase-databases
#2
Lindsay M Gorrell, Roger M Engel, Reidar P Lystad, Benjamin T Brown
BACKGROUND: Reporting of adverse events in randomized clinical trials (RCTs) is encouraged by the authors of The Consolidated Standards of Reporting Trials (CONSORT) statement. With robust methodological design and adequate reporting, RCTs have the potential to provide useful evidence on the incidence of adverse events associated with spinal manipulative therapy (SMT). During a previous investigation, it became apparent that comprehensive search strategies combining text words with indexing terms was not sufficiently sensitive for retrieving records that were known to contain reports on adverse events...
March 14, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28268027/a-feasibility-study-to-assess-vibration-and-sound-from-zygapophyseal-joints-during-motion-before-and-after-spinal-manipulation
#3
Gregory D Cramer, Matthew Budavich, Preetam Bora, Kim Ross
OBJECTIVE: This feasibility study used novel accelerometry (vibration) and microphone (sound) methods to assess crepitus originating from the lumbar spine before and after side-posture spinal manipulative therapy (SMT). METHODS: This study included 5 healthy and 5 low back pain (LBP) participants. Nine accelerometers and 1 specialized directional microphone were applied to the lumbar region, allowing assessment of crepitus. Each participant underwent full lumbar ranges of motion (ROM), bilateral lumbar SMT, and repeated full ROM...
March 3, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28259496/integrative-acupuncture-and-spinal-manipulative-therapy-versus-either-alone-for-low-back-pain-a-randomized-controlled-trial-feasibility-study
#4
Anupama Kizhakkeveettil, Kevin A Rose, Gena E Kadar, Eric L Hurwitz
OBJECTIVES: The objective of this study was to assess the feasibility of conducting a large-scale randomized controlled trial (RCT) examining whether an integrative care model combining spinal manipulative therapy (SMT) and acupuncture can lead to better outcomes for low back pain (LBP) than either therapy alone. METHODS: This study was conducted at a complementary and alternative medicine university health center. Participants with acute or chronic LBP were randomized to (1) acupuncture, (2) SMT, or (3) integrative acupuncture and SMT groups...
March 1, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28229085/folate-receptor-alpha-is-more-than-just-a-folate-transporter
#5
Vineet Mohanty, M Rizwan Siddiqui, Tadanori Tomita, Chandra Shekhar Mayanil
Until recently folate receptor alpha (FRα) has only been considered as a folate transporter. However, a novel role of FRα as a transcription factor was reported by our lab. More recently our lab showed a novel pleiotropic role of FRα: (a) direct transcriptional activation of Oct4, Sox2, and Klf4 genes; and (b) repression of biogenesis of miRNAs that target these genes or their effector molecules. These observations beg a question: "Can a simple molecule such as folate be used to manipulate the production and/or differentiation of endogenous neural stem cells (NSCs), which may hold promise for future therapies?" Conditions such as spinal cord injury, motor neuron diseases, Alzheimer's disease and multiple sclerosis may benefit from increasing stem cell pool and promoting specific pathways of differentiation...
2017: Neurogenesis (Austin, Tex.)
https://www.readbyqxmd.com/read/28215058/effect-of-cervical-versus-thoracic-spinal-manipulation-on-peripheral-neural-features-and-grip-strength-in-subjects-with-chronic-mechanical-neck-pain-a-randomized-controlled-trial
#6
Francisco Bautista-Aguirre, Ángel Oliva-Pascual-Vaca, Alberto M Heredia-Rizo, Juan J Boscá-Gandía, François Ricard, Cleofás Rodriguez-Blanco
BACKGROUND: Cervical and thoracic spinal manipulative therapy has shown positive impact for relief of pain and improve function in non-specific mechanical neck pain. Several attempts have been made to compare their effectiveness although previous studies lacked a control group, assessed acute neck pain or combined thrust and nonthrust techniques. AIM: To compare the immediate effects of cervical and thoracic spinal thrust manipulations on mechanosensitivity of upper limb nerve trunks and grip strength in patients with chronic non-specific mechanical neck pain...
February 17, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28196632/procedure-selection-and-patient-positioning-influence-spine-kinematics-during-high-velocity-low-amplitude-spinal-manipulation-applied-to-the-low-back
#7
Spencer Bell, Kevin D'Angelo, Gregory N Kawchuk, John J Triano, Samuel J Howarth
OBJECTIVES: This investigation compared indirect 3-dimensional angular kinematics (position, velocity, and acceleration) of the lumbar spine for 2 different high-velocity, low-amplitude (HVLA) spinal manipulation procedures (lumbar spinous pull or push), and altered initial patient lower limb posture. METHODS: Twenty-four participants underwent 6 HVLA procedures directed toward the presumed L4 vertebra, reflecting each combination of 2 variants of a spinal manipulation application technique (spinous pull and push) and 3 initial hip flexion angles (0°, 45°, and 90°) applied using a right lateral recumbent patient position...
February 10, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28196631/effects-of-12-weeks-of-chiropractic-care-on-central-integration-of-dual-somatosensory-input-in-chronic-pain-patients-a-preliminary-study
#8
Heidi Haavik, Imran Khan Niazi, Kelly Holt, Bernadette Murphy
OBJECTIVE: The purpose of this preliminary study was to assess whether the dual somatosensory evoked potential (SEP) technique is sensitive enough to measure changes in cortical intrinsic inhibitory interactions in patients with chronic neck or upper extremity pain and, if so, whether changes are associated with changes in pain scores. METHODS: The dual peripheral nerve stimulation SEP ratio technique was used for 6 subjects with a history of chronic neck or upper limb pain...
February 10, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28192793/nonpharmacologic-therapies-for-low-back-pain-a-systematic-review-for-an-american-college-of-physicians-clinical-practice-guideline
#9
Roger Chou, Richard Deyo, Janna Friedly, Andrea Skelly, Robin Hashimoto, Melissa Weimer, Rochelle Fu, Tracy Dana, Paul Kraegel, Jessica Griffin, Sara Grusing, Erika D Brodt
Background: A 2007 American College of Physicians guideline addressed nonpharmacologic treatment options for low back pain. New evidence is now available. Purpose: To systematically review the current evidence on nonpharmacologic therapies for acute or chronic nonradicular or radicular low back pain. Data Sources: Ovid MEDLINE (January 2008 through February 2016), Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and reference lists...
February 14, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28192789/noninvasive-treatments-for-acute-subacute-and-chronic-low-back-pain-a-clinical-practice-guideline-from-the-american-college-of-physicians
#10
Amir Qaseem, Timothy J Wilt, Robert M McLean, Mary Ann Forciea
Description: The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on noninvasive treatment of low back pain. Methods: Using the ACP grading system, the committee based these recommendations on a systematic review of randomized, controlled trials and systematic reviews published through April 2015 on noninvasive pharmacologic and nonpharmacologic treatments for low back pain. Updated searches were performed through November 2016...
February 14, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28191306/chiropractic-management-of-post-spinal-cord-stimulator-spine-pain-a-case-report
#11
Rachel M Perrucci, Christopher M Coulis
BACKGROUND: A brief overview of failed back surgery syndrome, with emphasis on low back pain status post spinal cord stimulation, and post-surgical spinal manipulation is presented. CASE PRESENTATION: Four cases of patients within the VA Connecticut Health Care System presenting between July 2014 and July 2015 reporting low back pain after surgical insertion of spinal cord stimulators are discussed. This study describes the outcomes experienced by four patients with low back pain status post implanted spinal cord stimulators receiving manual therapy in the form of lumbar spine manipulation or mobilization...
2017: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/28167971/glucose-metabolic-changes-in-the-brain-and-muscles-of-patients-with-nonspecific-neck-pain-treated-by-spinal-manipulation-therapy-a-18-f-fdg-pet-study
#12
Akie Inami, Takeshi Ogura, Shoichi Watanuki, Md Mehedi Masud, Katsuhiko Shibuya, Masayasu Miyake, Rin Matsuda, Kotaro Hiraoka, Masatoshi Itoh, Arlan W Fuhr, Kazuhiko Yanai, Manabu Tashiro
Objective. The aim of this study was to investigate changes in brain and muscle glucose metabolism that are not yet known, using positron emission tomography with [(18)F]fluorodeoxyglucose ([(18)F]FDG PET). Methods. Twenty-one male volunteers were recruited for the present study. [(18)F]FDG PET scanning was performed twice on each subject: once after the spinal manipulation therapy (SMT) intervention (treatment condition) and once after resting (control condition). We performed the SMT intervention using an adjustment device...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28146021/spinal-tissue-loading-created-by-different-methods-of-spinal-manipulative-therapy-smt-application
#13
Martha Funabashi, François Nougarou, Martin Descarreaux, Narasimha Prasad, Gregory N Kawchuk
STUDY DESIGN: Comparative study using robotic replication of SMT vertebral kinematics together with serial dissection. OBJECTIVE: To quantify loads created in cadaveric spinal tissues arising from three different forms of SMT application. SUMMARY OF BACKGROUND DATA: There exist many distinct methods by which to apply spinal manipulative therapy (SMT). It is not known presently if different forms of SMT application have different effects on spinal tissues...
January 31, 2017: Spine
https://www.readbyqxmd.com/read/28122640/rational-and-design-of-an-individual-participant-data-meta-analysis-of-spinal-manipulative-therapy-for-chronic-low-back-pain-a-protocol
#14
A de Zoete, M R de Boer, M W van Tulder, S M Rubinstein, M Underwood, J A Hayden, J Kalter, R Ostelo
BACKGROUND: Chronic low back pain (LBP) is the leading cause of pain and disability, resulting in a major socioeconomic impact. The Cochrane Review which examined the effect of spinal manipulative therapy (SMT) for chronic LBP concluded that SMT is moderately effective, but was based on conventional meta-analysis of aggregate data. The use of individual participant data (IPD) from trials allows for a more precise estimate of the treatment effect and has the potential to identify moderators and/or mediators...
January 26, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28093705/manipulation-of-oxygen-and-endoplasmic-reticulum-stress-factors-as-possible-interventions-for-treatment-of-multiple-sclerosis-evidence-for-and-against
#15
Paul Eggleton, Gary R Smerdon, Janet E Holley, Nicholas J Gutowski
Multiple sclerosis (MS) is normally considered a chronic inflammatory disease of the central nervous system (CNS), where T-cells breaching the blood brain barrier react against proteins of the axonal myelin sheaths, leading to focal plaques and demyelination in the brain and spinal cord. Many current therapies are immunosuppressive in nature and are designed to target the immune system at an early stage of the disease. But there is no cure and MS may evolve into a neurodegenerative disease, where immunomodulatory treatments appear less effective...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28073291/future-of-raav-gene-therapy-platform-for-rnai-gene-editing-and-beyond
#16
Paul N Valdmanis, Mark A Kay
The use of recombinant adeno-associated viruses (rAAVs) ushered in a new millennium of gene transfer for therapeutic treatment of a number of conditions, including congenital blindness, hemophilia, and spinal muscular atrophy. rAAV vectors have remarkable staying power from a therapeutic standpoint, withstanding several ebbs and flows. As new technologies such as clustered regularly interspaced short palindromic repeat genome editing emerge, it is now the delivery tool-the AAV vector-that is the stalwart. The long-standing safety of this vector in a multitude of clinical settings makes rAAV a selling point in the advancement of approaches for gene replacement, gene knockdown, gene editing, and genome modification/engineering...
January 10, 2017: Human Gene Therapy
https://www.readbyqxmd.com/read/28055091/spinal-manipulation-and-mobilization-therapy-for-cervicogenic-headache
#17
Michael A Seffinger, Melissa Yunting Tang
No abstract text is available yet for this article.
January 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28042118/post-operative-neuropathy-after-total-hip-arthroplasty
#18
REVIEW
E P Su
Nerve palsy is a well-described complication following total hip arthroplasty, but is highly distressing and disabling. A nerve palsy may cause difficulty with the post-operative rehabilitation, and overall mobility of the patient. Nerve palsy may result from compression and tension to the affected nerve(s) during the course of the operation via surgical manipulation and retractor placement, tension from limb lengthening or compression from post-operative hematoma. In the literature, hip dysplasia, lengthening of the leg, the use of an uncemented femoral component, and female gender are associated with a greater risk of nerve palsy...
January 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28025254/shaping-the-output-of-lumbar-flexor-motoneurons-by-sacral-neuronal-networks
#19
Meir Cherniak, Lili Anglister, Aharon Lev-Tov
The ability to improve motor function in spinal cord injury patients by reactivating spinal central pattern generators (CPGs) requires the elucidation of neurons and pathways involved in activation and modulation of spinal networks in accessible experimental models. Previously we reported on adrenoceptor-dependent sacral control of lumbar-flexor motoneuron firing in newborn rats. The current work focuses on clarification of the circuitry and connectivity involved in this unique modulation and its potential use...
December 26, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28017603/guideline-for-reporting-interventions-on-spinal-manipulative-therapy-consensus-on-interventions-reporting-criteria-list-for-spinal-manipulative-therapy-circle-smt
#20
Ruud Groeneweg, Sidney M Rubinstein, Rob A B Oostendorp, Raymond W J G Ostelo, Maurits W van Tulder
OBJECTIVE: The aim of the Consensus on Interventions Reporting Criteria List for Spinal Manipulative Therapy (CIRCLe SMT) study was to develop a criteria list for reporting spinal manipulative therapy (SMT). METHODS: A Delphi procedure was conducted from September 2011 to April 2013 and consisted of international experts in the field of SMT. The authors formed a steering committee and invited participants, selected initial items, structured the comments of the participants after each Delphi round, and formulated the feedback...
February 2017: Journal of Manipulative and Physiological Therapeutics
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