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Dent's disease

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https://www.readbyqxmd.com/read/29104392/association-between-fever-and-primary-tooth-eruption-a-systematic-review-and-meta-analysis
#1
REVIEW
Mariana A Nemezio, Katharina Mh De Oliveira, Priscilla C Romualdo, Alexandra M Queiroz, Francisco Wg Paula-E-Silva, Raquel Ab Silva, Erika C Küchler
Aim: To perform a systematic review and meta-analysis to establish if fever is associated with primary tooth eruption. Materials and methods: Literature searches involved Pubmed, MEDLINE, Web of Science, Scopus and Cochrane. The potentially relevant studies had the full text analyzed. Only studies concerning fever during eruption period of primary tooth in humans were included. Papers in non-English language, and papers that included syndromic patients or patients with any disease were excluded...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29104385/implementation-of-game-based-oral-health-education-vs-conventional-oral-health-education-on-children-s-oral-health-related-knowledge-and-oral-hygiene-status
#2
Azhar Malik, Sumit Sabharwal, Aina Kumar, Praveen Singh Samant, Abishek Singh, Vineet Kumar Pandey
Introduction: For the prevention of oral health problems, health education of schoolchildren has a vital role. The oral health status of the children can be improved if health promotion in schools is conducted in a comprehensive and interesting manner. Objective: Effectivity of game-based oral health education over conventional on the oral health-related knowledge and oral hygiene status among 8- to 12-year-old schoolchildren. Materials and methods: A total of 150 children aged 8 to 12 years were divided into two groups...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29089804/the-framingham-risk-score-underestimates-the-risk-of-cardiovascular-events-in-the-her2-positive-breast-cancer-population
#3
W Law, C Johnson, M Rushton, S Dent
INTRODUCTION: Patients with breast cancer (bca) who overexpress her2 (the human epidermal growth factor receptor 2) are at risk for cardiotoxicity when treated with anthracycline-based chemotherapy and her2-targeted agents. The Framingham risk score (frs) is a validated tool that stratifies patients into high-, intermediate-, or low-risk groups and calculates their 10-year risk of developing cardiovascular disease (cvd) based on past medical history, systolic blood pressure, and measurement of serum lipids...
October 2017: Current Oncology
https://www.readbyqxmd.com/read/29058463/genetic-analysis-of-dent-s-disease-and-functional-research-of-clcn5-mutations
#4
Ya Zhang, Xiaoyan Fang, Hong Xu, Qian Shen
Dent's disease is an X-linked inherited renal disease. Patients with Dent's disease often carry mutations in genes encoding the Cl(-)/H(+) exchanger ClC-5 and/or inositol polyphosphate 5-phosphatase (OCRL1). However, the mutations involved and the biochemical effects of these mutations are not fully understood. To characterize genetic changes in Dent's disease patients, in this study, samples from nine Chinese patients were subjected to genetic analysis. Among the nine patients, six were classified as having Dent-1 disease, one had Dent-2 disease, and two could not be classified...
October 23, 2017: DNA and Cell Biology
https://www.readbyqxmd.com/read/29045964/-increased-serum-c-c-chemokine-ligand-19-levels-correlated-with-b-cell-abnormalities-in-systemic-lupus-erythematosus
#5
H J Liu, L J Shi, F L Hu, H H Yao, Z G Li, Y Jia
OBJECTIVE: To detect the levels of serum C-C chemokine ligand 19 (CCL19) in patients with systemic lupus erythematosus (SLE) and to evaluate the correlation between CCL19 expression and clinical features and laboratory parameters, trying to reveal the possible role of CCL19 in the pathogenesis of systemic lupus erythematosus. METHODS: The levels of serum CCL19 were measured by enzyme linked immunosorbent assay (ELISA) in 90 patients with SLE and 30 healthy controls...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28943261/retinal-microcirculation-imaging-in-sickle-cell-disease-patients
#6
W Birkhoff, J de Vries, G Dent, A Verma, J L Kerkhoffs, A H F van Meurs, M de Kam, M Moerland, J Burggraaf
OBJECTIVES: To explore the feasibility of a new quantitative method for microvascular function: non-invasive retinal function imaging (RFI). in sickle cell disease (SCD) patients and healthy controls and have it benchmarked against Laser Speckle Contrast Imaging (LSCI) measurements. METHODS: The variability of Microvascular measurements was assessed in 8 SCD patients and 8 healthy matched controls. Measurements were conducted twice on two different study days. RFI was performed for assessment of arterial and venous retinal blood flow...
September 22, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28931756/monocyte-dysregulation-and-systemic-inflammation-during-pediatric-falciparum-malaria
#7
Katherine R Dobbs, Paula Embury, John Vulule, Peter S Odada, Bruce A Rosa, Makedonka Mitreva, James W Kazura, Arlene E Dent
BACKGROUND: Inflammation and monocytes are thought to be important to human malaria pathogenesis. However, the relationship of inflammation and various monocyte functions to acute malaria, recovery from acute malaria, and asymptomatic parasitemia in endemic populations is poorly understood. METHODS: We evaluated plasma cytokine levels, monocyte subsets, monocyte functional responses, and monocyte inflammatory transcriptional profiles of 1- to 10-year-old Kenyan children at the time of presentation with acute uncomplicated malaria and at recovery 6 weeks later; these results were compared with analogous data from asymptomatic children and adults in the same community...
September 21, 2017: JCI Insight
https://www.readbyqxmd.com/read/28927284/shared-medical-appointments-for-patients-with-a-nondiabetic-physical-chronic-illness-a-systematic-review
#8
F Kelly, C Liska, R Morash, J Hu, S L Carroll, R Shorr, S Dent, D Stacey
Objectives Shared medical appointments are group appointments, with an optional individual consultation, for patients diagnosed with chronic illnesses. Shared medical appointments improve diabetes management, but little is known about their use for other illnesses. The objective was to determine the effect that shared medical appointments have on patients with a physical chronic illness, healthcare providers, and the healthcare system. Methods A systematic review was conducted searching databases from January 1970 to September 2016...
January 1, 2017: Chronic Illness
https://www.readbyqxmd.com/read/28890623/childhood-occurrence-of-pemphigus
#9
Raju U Patil, Rajesh T Anegundi, Kumar R Gujjar, K R Indushekar
Pemphigus is a chronic mucocutaneous disease that initially manifests in the form of intraoral blisters which spread to other mucous membrane and skin. This study describes an unusual case of chronic generalized childhood pemphigus disease in an 11-year-old girl, who presented with multiple vesicles all over her body. Such a condition is seen more often in older people rather than children. It is crucial for dental professionals to be familiar with the diagnosis of bullous skin diseases in children and adolescents, especially in its initial stages in order to prevent the serious consequences and morbidity...
April 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28890613/assessment-of-vitamin-b12-and-its-correlation-with-dental-caries-and-gingival-diseases-in-10-to-14-year-old-children-a-cross-sectional-study
#10
Shivayogi M Hugar, Neha S Dhariwal, Andleeb Majeed, Chandrashekhar Badakar, Niraj Gokhale, Laresh Mistry
AIM: To assess the level of vitamin B12 and correlate it with dental caries [decayed, missing, and filled permanent teeth (DMFT) score] and gingival diseases [plaque index (PI) and gingival index (GI)]. DESIGN: Healthy children according to the inclusion criteria were selected by the computerized randomization method from a school to assess the vitamin B12 levels using Centaur/ Versace machine. MATERIALS AND METHODS: Blood samples were collected to assess vitamin B12 levels using automated analyzer...
April 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28815356/dent-disease-in-poland-what-we-have-learned-so-far
#11
Marcin Zaniew, Małgorzata Mizerska-Wasiak, Iga Załuska-Leśniewska, Piotr Adamczyk, Katarzyna Kiliś-Pstrusińska, Adam Haliński, Jan Zawadzki, Beata S Lipska-Ziętkiewicz, Krzysztof Pawlaczyk, Przemysław Sikora, Michael Ludwig, Maria Szczepańska
PURPOSE: Dent disease (DD) is a rare tubulopathy characterized by proximal tubular dysfunction leading to chronic kidney disease (CKD). The aim of the study was to characterize patients with DD in Poland. METHODS: A retrospective analysis of a national cohort with genetically confirmed diagnosis. RESULTS: Of 24 males, all patients except one carried mutations in the CLCN5 gene; in one patient a mutation in the OCRL gene was disclosed. Molecular diagnosis was delayed 1 year on average (range 0-21 years)...
November 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28800861/ipatasertib-plus-paclitaxel-versus-placebo-plus-paclitaxel-as-first-line-therapy-for-metastatic-triple-negative-breast-cancer-lotus-a-multicentre-randomised-double-blind-placebo-controlled-phase-2-trial
#12
RANDOMIZED CONTROLLED TRIAL
Sung-Bae Kim, Rebecca Dent, Seock-Ah Im, Marc Espié, Sibel Blau, Antoinette R Tan, Steven J Isakoff, Mafalda Oliveira, Cristina Saura, Matthew J Wongchenko, Amy V Kapp, Wai Y Chan, Stina M Singel, Daniel J Maslyar, José Baselga
BACKGROUND: The oral AKT inhibitor ipatasertib is being investigated in cancers with a high prevalence of PI3K/AKT pathway activation, including triple-negative breast cancer. The LOTUS trial investigated the addition of ipatasertib to paclitaxel as first-line therapy for triple-negative breast cancer. METHODS: In this randomised, placebo-controlled, double-blind, phase 2 trial, women aged 18 years or older with measurable, inoperable, locally advanced or metastatic triple-negative breast cancer previously untreated with systemic therapy were recruited from 44 hospitals in South Korea, the USA, France, Spain, Taiwan, Singapore, Italy, and Belgium...
October 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28733699/a-prospective-study-of-docetaxel-associated-pain-syndrome
#13
Nicholas Chiu, Liying Zhang, Rebecca Dent, Angie Giotis, Jenna van Draanen, Daniela Gallo-Hershberg, Leonard Chiu, Ronald Chow, Bo Angela Wan, Mark Pasetka, Jordan Stinson, Erica Stacey, Sunil Verma, Henry Lam, Edward Chow, Carlo DeAngelis
PURPOSE: To investigate the natural history of taxane-associated acute pain syndrome (TAPS) in a docetaxel patient cohort and to examine the long-term manifestation of TAPS. PATIENTS AND METHODS: For three consecutive treatment cycles, taxane-naive breast cancer patients completed diaries on days 1-7, 14, and 21 and telephone questionnaires 1, 3, 6, 9, and 12 months following treatment. Questionnaires to assess pain and interference were adapted from the Brief Pain Inventory...
July 22, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28717862/practical-considerations-for-the-use-of-subcutaneous-treatment-in-the-management-of-dyslipidaemia
#14
REVIEW
Franck Boccara, Ricardo Dent, Luis Ruilope, Paul Valensi
Suboptimal drug adherence represents a major challenge to effective primary and secondary prevention of cardiovascular disease. While adherence is influenced by multiple considerations, polypharmacy and dosing frequency appear to be rate-limiting factors in patient satisfaction and subsequent adherence. The cardiovascular and metabolic therapeutic areas have recently benefited from a number of advances in drug therapy, in particular protease proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors and incretin-based therapies, respectively...
August 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28710589/primary-care-physician-perspectives-on-barriers-to-statin-treatment
#15
Rikki M Tanner, Monika M Safford, Keri L Monda, Benjamin Taylor, Ronan O'Beirne, Melanie Morris, Lisandro D Colantonio, Ricardo Dent, Paul Muntner, Robert S Rosenson
PURPOSE: Discontinuation of statin therapy represents a major challenge for effective cardiovascular disease prevention. It is unclear how often primary care physicians (PCPs) re-initiate statins and what barriers they encounter. We aimed to identify PCP perspectives on factors influencing statin re-initiation. METHODS: We conducted six nominal group discussions with 23 PCPs from the Deep South Continuing Medical Education network. PCPs answered questions about statin side effects, reasons their patients reported for discontinuing statins, how they respond when discontinuation is reported, and barriers they encounter in getting their patients to re-initiate statin therapy...
July 14, 2017: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/28710211/occupational-risk-for-legionella-infection-among-dental-healthcare-workers-meta-analysis-in-occupational-epidemiology
#16
Stefano Petti, Matteo Vitali
OBJECTIVE: The occupational risk for Legionella infection among dental healthcare workers (DHCWs) is conjectured because of the risk of routine inhalation of potentially contaminated aerosols produced by the dental instruments. Nevertheless, occupational epidemiology studies are contrasting. This meta-analysis assessed the level of scientific evidence regarding the relative occupational risk for Legionella infection among DHCWs. METHODS: Literature search was performed without time and language restrictions, using broad data banks (PubMed, Scopus, Web of Science, GOOGLE Scholar) and generic keywords ('legionella' AND 'dent*')...
July 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28678172/factors-influencing-the-accuracy-of-infectious-disease-reporting-in-migrants-a-scoping-review
#17
REVIEW
Paolo Giorgi Rossi, Flavia Riccardo, Annamaria Pezzarossi, Paola Ballotari, Maria Grazia Dente, Christian Napoli, Antonio Chiarenza, Cesar Velasco Munoz, Teymur Noori, Silvia Declich
We conducted a scoping review of literature to improve our understanding of the accuracy of infectious disease monitoring in migrants in the Europe. We searched PubMed for papers relevant to the topic including: case reports, observational and experimental studies, reviews, guidelines or policy documents; published after 1994. We identified 532 papers, 27 of which were included in the review. Legislation and right to access health care influence both the accuracy of rates and risk measures under estimating the at risk population, i...
July 5, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28669993/the-5-phosphatase-ocrl-in-lowe-syndrome-and-dent-disease-2
#18
REVIEW
Maria Antonietta De Matteis, Leopoldo Staiano, Francesco Emma, Olivier Devuyst
Lowe syndrome is an X-linked disease that is characterized by congenital cataracts, central hypotonia, intellectual disability and renal Fanconi syndrome. The disease is caused by mutations in OCRL, which encodes an inositol polyphosphate 5-phosphatase (OCRL) that acts on phosphoinositides - quantitatively minor constituents of cell membranes that are nonetheless pivotal regulators of intracellular trafficking. In this Review we summarize the considerable progress made over the past decade in understanding the cellular roles of OCRL in regulating phosphoinositide balance along the endolysosomal pathway, a fundamental system for the reabsorption of proteins and solutes by proximal tubular cells...
August 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28654583/tumor-to-nipple-distance-as-a-predictor-of-nipple-involvement-expanding-the-inclusion-criteria-for-nipple-sparing-mastectomy
#19
Briar L Dent, Jake A Miller, Daniel J Eden, Alexander Swistel, Mia Talmor
BACKGROUND: A tumor-to-nipple distance of greater than 2 cm has traditionally been considered a criterion for nipple-sparing mastectomy. This study evaluates whether magnetic resonance imaging and sonographic measurements of tumor-to-nipple distance accurately reflect the risk of nipple involvement by disease. METHODS: All nipple-sparing mastectomy cases with implant-based reconstruction performed by the senior author between July 2006 and December 2014 were retrospectively reviewed...
July 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28644091/prevention-of-cardiovascular-disease-in-patients-with-familial-hypercholesterolaemia-the-role-of-pcsk9-inhibitors
#20
Ivan Pećin, Merel L Hartgers, G Kees Hovingh, Ricardo Dent, Željko Reiner
Familial hypercholesterolaemia is an autosomal dominant inherited disorder characterised by elevated low-density lipoprotein cholesterol levels and consequently an increased risk of atherosclerotic cardiovascular disease (ASCVD). Familial hypercholesterolaemia is relatively common, but is often underdiagnosed and undertreated. Cardiologists are likely to encounter many individuals with familial hypercholesterolaemia; however, patients presenting with premature ASCVD are rarely screened for familial hypercholesterolaemia and fasting lipid levels are infrequently documented...
September 2017: European Journal of Preventive Cardiology
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