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JOURNAL ARTICLE
Riccardo Antonio Ricciuti, Fabrizio Mancini, Giusy Guzzi, Daniele Marruzzo, Alessandro Dario, Alessandro Della Puppa, Alessandro Ricci, Andrea Barbanera, Andrea Talacchi, Andreas Schwarz, Antonino Germanò, Antonino Raco, Antonio Colamaria, Antonio Santoro, Riccardo Boccaletti, Carlo Conti, Carlo Conti, Nunzia Cenci, Christian Cossandi, Claudio Bernucci, Corrado Lucantoni, Giovanni Battista Costella, Diego Garbossa, Donato Carlo Zotta, Federico De Gonda, Felice Esposito, Flavio Giordano, Giancarlo D'Andrea, Gianluca Piatelli, Gianluigi Zona, Giannantonio Spena, Giovanni Tringali, Giuseppe Barbagallo, Carlo Giussani, Maurizio Gladi, Andrea Landi, Angelo Lavano, Letterio Morabito, Luciano Mastronardi, Marco Locatelli, Michele D'Agruma, Michele Maria Lanotte, Nicola Montano, Orazio Santo Santonocito, Angelo Pompucci, Raffaele de Falco, Franco Randi, Sara Bruscella, Ivana Sartori, Francesco Signorelli, Luigino Tosatto, Roberto Trignani, Vincenzo Esposito, Gualtiero Innocenzi, Sergio Paolini, Vincenzo Vitiello, Michele Alessandro Cavallo, Francesco Sala
INTRODUCTION: Intraoperative Neurophysiological Monitoring (IOM) is widely used in neurosurgery but specific guidelines are lacking. Therefore, we can assume differences in IOM application between Neurosurgical centers. RESEARCH QUESTION: The section of Functional Neurosurgery of the Italian Society of Neurosurgery realized a survey aiming to obtain general data on the current practice of IOM in Italy. MATERIALS AND METHODS: A 22-item questionnaire was designed focusing on: volume procedures, indications, awake surgery, experience, organization and equipe...
2024: Brain Spine
#22
REVIEW
Daniel Umansky, Kate Elzinga, Rajiv Midha
Advancement in microsurgical techniques and innovative approaches including greater use of nerve and tendon transfers have resulted in better peripheral nerve injury (PNI) surgical outcomes. Clinical evaluation of the patient and their injury factors along with a shift toward earlier time frame for intervention remain key. A better understanding of the pathophysiology and biology involved in PNI and specifically mononeuropathies along with advances in ultrasound and magnetic resonance imaging allow us, nowadays, to provide our patients with a logical and sophisticated approach...
2024: Handbook of Clinical Neurology
#23
REVIEW
Thomas A Miller, Douglas C Ross
The sciatic nerve is the body's largest peripheral nerve. Along with their two terminal divisions (tibial and fibular), their anatomic location makes them particularly vulnerable to trauma and iatrogenic injuries. A thorough understanding of the functional anatomy is required to adequately localize lesions in this lengthy neural pathway. Proximal disorders of the nerve can be challenging to precisely localize among a range of possibilities including lumbosacral pathology, radiculopathy, or piriformis syndrome...
2024: Handbook of Clinical Neurology
#24
JOURNAL ARTICLE
Silvia Olivi, Paola Paglierani, Elisa Maietti, Paola Rucci, Gaia Musumeci, Carlotte Kiekens, Jacopo Visani, Carlo Sacco
OBJECTIVE: To describe the 2-year functional outcomes of nerve transfer (NT) for upper extremity reanimation. STUDY DESIGN: A prospective case series. SETTING: A highly specialized rehabilitation hospital for spinal cord injury (SCI) in Italy. INTERVENTION: Upper limb nerve transfer (32 NTs, 15 upper limbs). PARTICIPANTS: Twelve male individuals with traumatic SCI (AIS A or B, neurological level from C4 to C7) were enrolled; 24-month follow-up data were available for 11...
May 2, 2024: Journal of Spinal Cord Medicine
#25
JOURNAL ARTICLE
Jeong-Seo Kim
We herein review the use of electrocochleography (ECoG) to assess peripheral auditory system responsiveness in a growing population of cochlear implant (CI) users with preserved hearing in ears with implants. Twenty-eight recently published intracochlear ECoG articles were thoroughly reviewed to investigate the prognostic utility of intraoperative ECoG monitoring to assess hearing preservation, and the clinical applicability of postoperative ECoG for estimating audiometric thresholds and monitoring longitudinal changes in residual acoustic hearing in patients with EAS...
April 2024: Journal of Audiology & Otology
#26
Kshitiz Karki, Sugat Adhikari, Suraj Shrestha, Jenish Bhandari, Bidisha Baral, Aastha Baral
INTRODUCTION AND IMPORTANCE: Cytarabine, a pyrimidine analogue, is commonly used to treat multiple haematological conditions, such as acute leukaemias and lymphomas. One of the rare and less reported complications of cytarabine is peripheral neuropathy, in which peripheral nerves are damaged, often causing weakness, numbness, and pain, usually in the hands and feet. CASE PRESENTATION: The authors report the case of a 17-year-old male who developed a gradual onset of weakness and sensory loss in all four limbs during treatment with a conventional dose of cytarabine for acute myeloid leukaemia...
May 2024: Annals of Medicine and Surgery
#27
Suaad Hamsho, Ahmad Almohamed, Hasan Haydar, Yousef Alsaffaf, Enas Sultan, Yassen Sukkar, Waddah Kazkz
INTRODUCTION: Charcot-Marie-Tooth (CMT) is a group of inherited neuromuscular disorders that vary clinically and genetically. It is characterized by peripheral nerve damage, leading to muscle weakness and sensory loss. CASE PRESENTATION: A 13-year-old male presented to the rheumatology department with bilateral hearing impairment since the age of 3 years, pes cavus, and difficulties walking. Some family members had Achilles tendon lengthening surgery. During physical examination, the patient had a shortened Achilles tendon, there are high arches in the feet, curled toes, loss of touch sensation in the feet, ankles, and legs, atrophy in the foot muscles...
May 2024: Annals of Medicine and Surgery
#28
Brandon Toliver, Blaire Egan, Payton Sparks, Ashlyn Morris, Ivan Hadad
Regenerative peripheral nerve interface (RPNI) is a surgical technique whose indications include preventing or treating painful neuromas after amputation or peripheral nerve injuries. The procedure involves implanting the distal end of a transected peripheral nerve containing sensory fibers into a selected free muscle graft. Although RPNI procedures have primarily been used after limb amputations, select case reports detail the potential for RPNI to mitigate other sources of neuropathic pain, introducing novel uses to its clinical utility...
April 2024: Plastic and Reconstructive Surgery. Global Open
#29
REVIEW
Hanlin Chen, Guodong Feng, Yang Zhao
<b/>This study reviews the latest progress on the research of electrical stimulation（ES） in peripheral nerve regeneration, summarizes the parameters in preclinical experiments and discusses the effect on nerve regeneration. A detailed description is given in the study of conditioning electrical stimulation and nerve conduit scaffolding technology combined with ES, which have been hotly researched in recent years.
May 2024: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
#30
JOURNAL ARTICLE
Shuhang Fan, Jianbin Sun, Qin Wang, Na Sai, Qi Ji, Yuhua Zhu, Weidong Shen, Pu Dai, Shiming Yang, Dongyi Han, Weiju Han
Objective: To investigate the characteristics and prognosis of two anastomosis techniques in repairing facial nerve defects. Methods: A retrospective analysis was conducted on 30 patients who underwent facial nerve anastomosis（direct or rerouting） for facial nerve defects in our department from January 2012 to December 2021. Among them, 21 were male and 9 were female, with an average age of（37.53±11.33） years, all with unilateral onset. Preoperative House-Brackmann（H-B） facial nerve function grades were Ⅳ in 2 cases, Ⅴ in 9 cases, and Ⅵin 19 cases...
May 2024: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
#31
JOURNAL ARTICLE
Tingting Jin, Yongchuan Chai, Lu Xue, Yi Jiang, Na Xue, Zhaoyan Wang
Objective: To investigate the factors and efficacy of different surgical techniques used in facial nerve（FN） reconstruction. Methods: A retrospective analysis was conducted on 24 patients who underwent facial nerve reconstruction surgery in our department from January 2016 to January 2021. The duration of total facial nerve paralysis was less than 18 months. The study included 5 surgical techniques, including 6 cases of FN anastomosis（Group A）, 5 cases of FN grafting（sural nerve or great auricular nerve）（Group B）, 5 cases of side-to-end facial-hypoglossal nerve anastomosis（Group C）, 4 cases of side-to-end FN grafting（sural nerve or great auricular nerve） hypoglossal nerve anastomosis（Group D）, and 4 cases of dual nerve reanimation（Group E）...
May 2024: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
#32
JOURNAL ARTICLE
Dehua Meng, Qintong Xu, Zenggan Chen, Jianfeng Pan, Libo Jiang, Jiapeng Zou, Yaqin Yuan, Jian Zhang, William C Lineaweaver, Feng Zhang
BACKGROUND: Acellular nerve allografts (ANAs) were developed to replace the autologous nerve grafts (ANGs) to fill the peripheral nerve defects. Poor vascularization relative to ANGs has been a limitation of application of ANAs. METHODS: A total of 60 female Sprague-Dawley rats were assigned 3 groups. The rats in A group received ANGs, the rats in B group received ANAs, and the rats in C group were transplanted with ANA carrying endothelial cells (ANA + ECs). In the 1st, 2nd, 4th, and 12th postoperative weeks, 5 rats were selected from each group for evaluating sciatic function index (SFI), electrophysiology, maximum tetanic force recovery rate, tibialis anterior muscle weights recovery rate, and microvessel density...
May 1, 2024: Annals of Plastic Surgery
#33
JOURNAL ARTICLE
Ziqi Zeng, Yulan Bai, Weijiang Hao, Tiefeng Zhang, Jing Yang, Feng Wu, Xianqi Li
OBJECTIVE: Bell's palsy, also referred to as clinical manifestations of unilateral facial nerve palsy, encompasses downward angling of the corners of the mouth, the absence of forehead creases, and unilateral incomplete eyelid closure. The incidence of Bell's palsy has increased progressively in recent years, but the underlying mechanism of its occurrence remains unknown; therefore, it is essential to investigate both the cause and treatment of Bell's palsy. Member 2 of the Subfamily V Transient Receptor Potential Cation Channel is a mechanically and thermally sensitive ion channel that plays a crucial role in neural growth and development...
April 27, 2024: Journal of Stomatology, Oral and Maxillofacial Surgery
#34
JOURNAL ARTICLE
Qing Zhang, Li Wang, Ruirui Sun, Jian Gao, Tingting Liu
BACKGROUND: Pretreatment levels of serum carcinoembryonic antigen (CEA) and perineural invasion (PNI) are related to poor prognosis in colon cancer. We analyzed the CEA and PNI (defined as incorporation of carcinoembryonic antigen and perineural invasion (CP)-stage), which are included in the Tumor-Node-Metastasis (TNM) staging system of the American Joint Committee on Cancer (AJCC), and evaluated the survival prognosis of patients treated with surgery in I-III stage colon carcinoma. MATERIALS AND METHODS: We employed a retrospective study for eligible colon carcinoma patients obtained from the Surveillance, Epidemiology, and End Results (SEER) database between 2010 and 2015...
2024: Annali Italiani di Chirurgia
#35
JOURNAL ARTICLE
Samuel Knoedler, Konstantin Frank, Thomas Muehlberger, Ali-Farid Safi, Sebastian Cotofana, Filippo A G Perozzo, Adriana C Panayi, Bahman Guyuron, Jeffrey E Janis, Michael Alfertshofer
Headache disorders (HD) remain a nationwide challenge for the US healthcare system affecting nearly 60% of the US population. Surgical deactivation of the peripheral trigger site, also referred to as headache surgery, represents an effective treatment for patients with refractory HD pain or non-response to pharmacological regimes. Research stemming from other surgical specialties has underlined the clinical relevance of neural interconnections in refining diagnostic algorithms, adapting surgical techniques, and improving overall patient outcomes...
April 29, 2024: Plastic and Reconstructive Surgery
#36
JOURNAL ARTICLE
Juan Pablo Mejia, Brandon Galviz Tabares, Carlos Miguel Ruiz Geithner
The purpose of this study was to assess the effects of protecting the facial nerve with a modified endaural approach with a peripheral dissection of the superficial musculoaponeurotic system to access the temporomandibular joint which allows an excellent operative field of visualization, multiple surgical procedures of the temporomandibular joint, and general care which improves the immediate postoperative period, making this a less morbid surgery. This study included 33 patients (39 sides) who underwent surgical treatment for disorders of the temporomandibular joint from the years 2021 to 2023 at the maxillofacial department of the clinic "Colsanitas" located in Bogota, Colombia...
April 29, 2024: Journal of Craniofacial Surgery
#37
JOURNAL ARTICLE
Morgan Yuan, Matteo Gallo, Lucas Gallo, Minh Hq Huynh, Mark McRae, Matthew C McRae, Achilleas Thoma, Christopher J Coroneos, Sophocles H Voineskos
Introduction: Painful neuromas are a common postoperative complication of limb amputation often treated with secondary reinnervation. Surgical reinnervation include Targeted Muscle Reinnervation (TMR) and Regenerative Peripheral Nerve Interface (RPNI), and can be primary and secondary. The aim of this review is to assess the effects of primary TMR/RPNI at the time of limb amputation on the incidence and intensity of post-operative neuroma and pain. Methods: This review was registered a priori on PROSPERO (CRD42021264360)...
May 2024: Plastic Surgery
#38
JOURNAL ARTICLE
Julia B Lichtenstein, Linden K Head, Gerald Wolff, Kirsty U Boyd
Background: The objective of this work is to: (i) evaluate the postoperative outcomes after lower extremity nerve transfer (LENT) in patients with peroneal nerve palsy, and (ii) evaluate the patient and surgical factors that best predict successful restoration of ankle dorsiflexion following nerve transfer. Methods: A retrospective cohort of prospectively collected data included all patients who underwent LENT (2010-2018). Two independent reviewers performed data collection. Primary outcome measures were: (i) clinically with British Medical Research Council (MRC) strength assessments, and (ii) electrodiagnostically with nascent motor unit potentials...
May 2024: Plastic Surgery
#39
REVIEW
Teng Wan, Qi-Cheng Li, Ming-Yu Qin, Yi-Lin Wang, Feng-Shi Zhang, Xiao-Meng Zhang, Yi-Chong Zhang, Pei-Xun Zhang
Neuroma, a pathological response to peripheral nerve injury, refers to the abnormal growth of nerve tissue characterized by disorganized axonal proliferation. Commonly occurring after nerve injuries, surgeries, or amputations, this condition leads to the formation of painful nodular structures. Traditional treatment options include surgical excision and pharmacological management, aiming to alleviate symptoms. However, these approaches often offer temporary relief without addressing the underlying regenerative challenges, necessitating the exploration of advanced strategies such as tissue-engineered materials for more comprehensive and effective solutions...
April 16, 2024: Biomolecules
#40
JOURNAL ARTICLE
Chaoqun Dong, Alejandro Carnicer-Lombarte, Filippo Bonafè, Botian Huang, Sagnik Middya, Amy Jin, Xudong Tao, Sanggil Han, Manohar Bance, Damiano G Barone, Beatrice Fraboni, George G Malliaras
Electrode arrays that interface with peripheral nerves are used in the diagnosis and treatment of neurological disorders; however, they require complex placement surgeries that carry a high risk of nerve injury. Here we leverage recent advances in soft robotic actuators and flexible electronics to develop highly conformable nerve cuffs that combine electrochemically driven conducting-polymer-based soft actuators with low-impedance microelectrodes. Driven with applied voltages as small as a few hundreds of millivolts, these cuffs allow active grasping or wrapping around delicate nerves...
April 26, 2024: Nature Materials
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