keyword
MENU ▼
Read by QxMD icon Read
search

space flight

keyword
https://www.readbyqxmd.com/read/28212709/erythrocyte-deformability-and-aggregation-responses-to-intermittent-and-continuous-artificial-gravity-exposure
#1
Grau Marijke, Abeln Vera, Vogt Tobias, Bloch Wilhelm, Schneider Stefan
Artificial gravity protocols are used to improve g-tolerance of aviators and discussed as countermeasure during prolonged space flight. Little is known about the impact of artificial gravity on the red blood cells (RBC). The purpose of the study was to test how artificial gravity affects RBC deformability and aggregation, which are important determinants of microcirculation. Nine male subjects were exposed to two hypergravity protocols using a short arm human centrifuge: a continuous (CONT) protocol with constant +2Gz for 30min and an intermittent (INTER) protocol with repeated intervals of +2Gz and rest...
February 2017: Life Sciences in Space Research
https://www.readbyqxmd.com/read/28212705/detection-of-dna-damage-by-space-radiation-in-human-fibroblasts-flown-on-the-international-space-station
#2
Tao Lu, Ye Zhang, Michael Wong, Alan Feiveson, Ramona Gaza, Nicholas Stoffle, Huichen Wang, Bobby Wilson, Larry Rohde, Louis Stodieck, Fathi Karouia, Honglu Wu
Although charged particles in space have been detected with radiation detectors on board spacecraft since the discovery of the Van Allen Belts, reports on the effects of direct exposure to space radiation in biological systems have been limited. Measurement of biological effects of space radiation is challenging due to the low dose and low dose rate nature of the radiation environment, and due to the difficulty in distinguishing the radiation effects from microgravity and other space environmental factors. In astronauts, only a few changes, such as increased chromosome aberrations in their lymphocytes and early onset of cataracts, are attributed primarily to their exposure to space radiation...
February 2017: Life Sciences in Space Research
https://www.readbyqxmd.com/read/28208390/geometry-and-design-of-origami-bellows-with-tunable-response
#3
Austin Reid, Frederic Lechenault, Sergio Rica, Mokhtar Adda-Bedia
Origami folded cylinders (origami bellows) have found increasingly sophisticated applications in space flight and medicine. In spite of this interest, a general understanding of the mechanics of an origami folded cylinder has been elusive. With a newly developed set of geometrical tools, we have found an analytic solution for all possible cylindrical rigid-face states of both Miura-ori and triangular tessellations. Although an idealized bellows in both of these families may have two allowed rigid-face configurations over a well-defined region, the corresponding physical device, limited by nonzero material thickness and forced to balance hinge and plate-bending energy, often cannot stably maintain a stowed configuration...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28205656/an-autonomous-lab-on-a-chip-for-space-flight-calibration-of-gravity-induced-transcellular-calcium-polarization-in-single-cell-fern-spores
#4
J Park, M L Salmi, W W A Wan Salim, A Rademacher, B Wickizer, A Schooley, J Benton, A Cantero, P F Argote, M Ren, M Zhang, D M Porterfield, A J Ricco, S J Roux, J L Rickus
This report describes the development of lab-on-a-chip device designed to measure changes in cellular ion gradients that are induced by changes in gravitational (g) forces. The bioCD presented here detects differential calcium ion concentrations outside of individual cells. The device includes sufficient replicates for statistical analysis of the gradients around multiple single cells and around control wells that are empty or include dead cells. In the data presented, the degree of the cellular response correlates with the magnitude of the g-force applied via rotation of the bioCD...
February 16, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28193030/dynamic-cluster-analysis-an-unbiased-method-for-identifying-a-2-element-containing-compounds-in-liquid-chromatographic-high-resolution-time-of-flight-mass-spectrometric-data
#5
Aaron John Christian Andersen, Per Juel Hansen, Kevin Jørgensen, Kristian Fog Nielsen
Dynamic cluster analysis (DCA) is an automated, unbiased technique which can identify Cl, Br, S, and other A + 2 element containing metabolites in liquid chromatographic high-resolution mass spectrometric data. DCA is based on three features, primarily the previously unutilized A + 1 to A + 2 isotope cluster spacing which is a strong classifier in itself but improved with the addition of the monoisotopic mass, and the well-known A:A+2 intensity ratio. Utilizing only the A + 1 to A + 2 isotope cluster spacing and the monoisotopic mass it was possible to filter a chromatogram for metabolites which contain Cl, Br, and S...
December 20, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/28173929/postflight-reconditioning-for-european-astronauts-a-case-report-of-recovery-after-six-months-in-space
#6
Nora Petersen, Gunda Lambrecht, Jonathan Scott, Natalie Hirsch, Maria Stokes, Joachim Mester
BACKGROUND: Postflight reconditioning of astronauts is understudied. Despite a rigorous, daily inflight exercise countermeasures programme during six months in microgravity (μG) on-board the International Space Station (ISS), physiological impairments occur and postflight reconditioning is still required on return to Earth. Such postflight programmes are implemented by space agency reconditioning specialists. Case Description and Assessments: A 38 year old male European Space Agency (ESA) crewmember's pre- and postflight (at six and 21 days after landing) physical performance from a six-month mission to ISS are described...
January 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28173928/the-role-of-physiotherapy-in-the-european-space-agency-strategy-for-preparation-and-reconditioning-of-astronauts-before-and-after-long-duration-space-flight
#7
Gunda Lambrecht, Nora Petersen, Guillaume Weerts, Casey Pruett, Simon Evetts, Maria Stokes, Julie Hides
Spaceflight and exposure to microgravity have wide-ranging effects on many systems of the human body. At the European Space Agency (ESA), a physiotherapist plays a key role in the multidisciplinary ESA team responsible for astronaut health, with a focus on the neuro-musculoskeletal system. In conjunction with a sports scientist, the physiotherapist prepares the astronaut for spaceflight, monitors their exercise performance whilst on the International Space Station (ISS), and reconditions the astronaut when they return to Earth...
January 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28153941/decreases-in-maximal-oxygen-uptake-following-long-duration-spaceflight-role-of-convective-and-diffusive-o2-transport-mechanisms
#8
Carl J Ade, Ryan M Broxterman, Alan Moore, Thomas J Barstow
We have previously predicted that the decrease in maximal oxygen uptake (VO2max) that accompanies time in microgravity reflects decrements in both convective and diffusive O2 transport to the mitochondria of the contracting myocytes. The aim of this investigation was therefore to quantify the relative changes in convective O2 transport (QO2) and O2 diffusing capacity (DO2) following long duration spaceflight. In 9 astronauts, resting hemoglobin concentration ([Hb]), VO2max, maximal cardiac output (QTmax), and differences in arterial and venous O2 contents (CaO2-CvO2) were obtained retrospectively for International Space Station Increments 19 through 33 (April 2009-November 2012)...
February 2, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28147690/continuous-time-of-flight-measurements-in-a-lissajous-configuration
#9
G Dobos, G Hárs
Short pulses used by traditional time-of-flight mass spectrometers limit their duty cycle, pose space-charge issues, and require high speed detectors and electronics. The motivation behind the invention of continuous time of flight mass spectrometers was to mitigate these problems, by increasing the number of ions reaching the detector and eliminating the need for fast data acquisition systems. The most crucial components of these spectrometers are their modulators: they determine both the maximal modulation frequency and the modulation depth...
January 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28139516/effects-of-head-down-tilt-on-nerve-conduction-in-rhesus-monkeys
#10
Bo Sun, Xiao-Yun Zhang, Li-Zhi Liu, Zhao-Hui Chen, Zhong-Quan Dai, Xu-Sheng Huang
BACKGROUND: Few studies have focused on peripheral nerve conduction during exposure to microgravity. The -6° head-down tilt (HDT) comprises an experimental model used to simulate the space flight environment. This study investigated nerve conduction characteristics of rhesus monkeys before and after prolonged exposure to HDT. METHODS: Six rhesus monkeys (3-4 years old) were tilted backward 6° from the horizontal. Nerve conduction studies (NCSs) were performed on the median, ulnar, tibial, and fibular motor nerves...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28133416/understanding-and-controlling-cu-catalyzed-graphene-nucleation-the-role-of-impurities-roughness-and-oxygen-scavenging
#11
Philipp Braeuninger-Weimer, Barry Brennan, Andrew J Pollard, Stephan Hofmann
The mechanism by which Cu catalyst pretreatments control graphene nucleation density in scalable chemical vapor deposition (CVD) is systematically explored. The intrinsic and extrinsic carbon contamination in the Cu foil is identified by time-of-flight secondary ion mass spectrometry as a major factor influencing graphene nucleation and growth. By selectively oxidizing the backside of the Cu foil prior to graphene growth, a drastic reduction of the graphene nucleation density by 6 orders of magnitude can be obtained...
December 27, 2016: Chemistry of Materials: a Publication of the American Chemical Society
https://www.readbyqxmd.com/read/28128778/the-contributions-of-occupational-science-to%C3%A2-the-readiness-of-long-duration-deep-space-exploration
#12
Janis Davis, Macy Burr, Maria Absi, Rochelle Telles, Howard Koh
BACKGROUND: This study introduces the contributions of occupational science (OS) to the preparation and support of astronauts during long duration space exploration. Given the hostile environment of space, it is not surprising that there is grave deterioration of both physical and mental health when off Earth. However, OS, through occupational therapy (OT), can identify strategies that maintain health and minimize disruptions in task performance for mission success. OBJECTIVE: To determine the gaps in NASA's preparation of astronauts for long duration space exploration and the viable contributions of OT...
2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28113842/mercury-ion-clock-for-a-nasa-technology-demonstration-mission
#13
Robert Tjoelker, John Prestage, Eric Burt, Pin Chen, Yong Chong, Sang Chung, William Diener, Todd Ely, Daphna Enzer, Hadi Mojaradi, Clayton Okino, Mike Pauken, David Robison, Brad Swenson, Blake Tucker, R Wang
There are many different atomic frequency standard technologies but few meet the demanding performance, reliability, size, mass, and power constraints required for space operation. JPL is developing a linear ion trap based mercury ion clock, referred to as DSAC (Deep Space Atomic Clock) under NASA's Technology Demonstration Mission (TDM) program. This clock is expected to provide a new capability with broad application to space based navigation and science. A one year flight demonstration is planned as a hosted payload following an early 2017 launch...
March 21, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28091925/changes-in-the-neurochemical-composition-of-motor-neurons-of-the-spinal-cord-in-mice-under-conditions-of-space-flight
#14
V V Porseva, V V Shilkin, A A Strelkov, I B Krasnov, P M Masliukov
Expression of choline acetyltransferase, 200-kDa neurofilament protein, 28-kDa calbindin, neuronal NO synthase, caspase 3, and Ki-67 in the motor neurons of spinal cord segments T3-T5 in male C57Bl/6 mice after 30-day space flight in the Bion-M1 biosatellite was studied by immunohistochemical methods. Under conditions space flight, the size of motoneurons increased, the number of neurons containing choline acetyltransferase and neurofilaments, decreased, and the number of calbindin-positive neurons increased; motoneurons, expressing neuronal NO synthase and caspase 3 appeared, while Ki-67 was not detected...
January 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28076365/gene-expression-profiling-in-slow-type-calf-soleus-muscle-of-30-days-space-flown-mice
#15
Guido Gambara, Michele Salanova, Stefano Ciciliot, Sandra Furlan, Martina Gutsmann, Gudrun Schiffl, Ute Ungethuem, Pompeo Volpe, Hanns-Christian Gunga, Dieter Blottner
Microgravity exposure as well as chronic disuse are two main causes of skeletal muscle atrophy in animals and humans. The antigravity calf soleus is a reference postural muscle to investigate the mechanism of disuse-induced maladaptation and plasticity of human and rodent (rats or mice) skeletal musculature. Here, we report microgravity-induced global gene expression changes in space-flown mouse skeletal muscle and the identification of yet unknown disuse susceptible transcripts found in soleus (a mainly slow phenotype) but not in extensor digitorum longus (a mainly fast phenotype dorsiflexor as functional counterpart to soleus)...
2017: PloS One
https://www.readbyqxmd.com/read/28074016/cari-7a-development-and-validation
#16
Kyle Copeland
Aircrew members can be exposed to higher annual doses of natural ionizing radiation than members of the general population in most parts of the world. The principal ionizing radiation to which they are exposed is galactic cosmic radiation (GCR). Among the particles present in the primary spectrum are heavy ions: relativistic nuclei of lithium and heavier elements. These ions have very high radiation weighting factors and can contribute significantly to the effective dose at altitudes above the Pfotzer maximum...
January 10, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28061915/prevalence-predictors-and-prevention-of-motion-sickness-in-zero-g-parabolic-flights
#17
John F Golding, Aurore C Paillard, Hervé Normand, Stéphane Besnard, Pierre Denise
INTRODUCTION: Zero-G parabolic flight reproduces the weightlessness of space for short periods. However, motion sickness may affect some fliers. The aim was to assess the extent of this problem and to find possible predictors and modifying factors. METHODS: Airbus zero-G flights consist of 31 parabolas performed in blocks. Each parabola consisted of 20 s of 0 g sandwiched by 20 s of hypergravity of 1.5-1.8 g. The survey covered N = 246 person-flights (193 men, 53 women), ages (M ± SD) 36...
January 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28058419/reactive-collisions-for-no-2-%C3%AE-n-4-s-at-temperatures-relevant-to-the-hypersonic-flight-regime
#18
Otoniel Denis-Alpizar, Raymond J Bemish, Markus Meuwly
The NO(X(2)Π) + N((4)S) reaction which occurs entirely in the triplet manifold of N2O is investigated using quasiclassical trajectories and quantum simulations. Fully-dimensional potential energy surfaces for the (3)A' and (3)A'' states are computed at the MRCI+Q level of theory and are represented using a reproducing kernel Hilbert space. The N-exchange and N2-formation channels are followed by using the multi-state adiabatic reactive molecular dynamics method. Up to 5000 K these reactions occur predominantly on the N2O (3)A'' surface...
January 18, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28050606/long-term-exposure-to-space-s-microgravity-alters-the-time-structure-of-heart-rate-variability-of-astronauts
#19
Kuniaki Otsuka, Germaine Cornelissen, Satoshi Furukawa, Yutaka Kubo, Mitsutoshi Hayashi, Koichi Shibata, Koh Mizuno, Tatsuya Aiba, Hiroshi Ohshima, Chiaki Mukai
BACKGROUND: Spaceflight alters human cardiovascular dynamics. The less negative slope of the fractal scaling of heart rate variability (HRV) of astronauts exposed long-term to microgravity reflects cardiovascular deconditioning. We here focus on specific frequency regions of HRV. METHODS: Ten healthy astronauts (8 men, 49.1 ± 4.2 years) provided five 24-hour electrocardiographic (ECG) records: before launch, 20.8 ± 2.9 (ISS01), 72.5 ± 3.9 (ISS02) and 152.8 ± 16...
December 2016: Heliyon
https://www.readbyqxmd.com/read/28039409/internal-jugular-pressure-increases-during-parabolic-flight
#20
David S Martin, Stuart M C Lee, Timothy P Matz, Christian M Westby, Jessica M Scott, Michael B Stenger, Steven H Platts
One hypothesized contributor to vision changes experienced by >75% of International Space Station astronauts is elevated intracranial pressure (ICP). While no definitive data yet exist, elevated ICP might be secondary to the microgravity-induced cephalad fluid shift, resulting in venous congestion (overfilling and distension) and inhibition of cerebrospinal and lymphatic fluid drainage from the skull. The objective of this study was to measure internal jugular venous pressure (IJVP) during normo- and hypo-gravity as an index of venous congestion...
December 2016: Physiological Reports
keyword
keyword
45383
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"