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https://www.readbyqxmd.com/read/28205136/a-comparative-study-of-the-risk-profile-of-hemodialysis-patients-in-a-for-profit-network-and-in-two-regional-registries-of-the-italian-society-of-nephrology
#1
Maurizio Postorino, Claudia Amato, Elena Mancini, Paola Carioni, Graziella D'Arrigo, Attilio Di Benedetto, Fabrizio Cerino, Carmela Marino, Antonio Vilasi, Giovanni Tripepi, Stefano Stuard, Giovanbattista Capasso, Antonio Santoro, Carmine Zoccali
In 2013, the Italian Society of Nephrology joined forces with Nephrocare-Italy to create a clinical research cohort of patients on file in the data-rich clinical management system (EUCLID) of this organization for the performance of observational studies in the hemodialysis (HD) population. To see whether patients in EUCLID are representative of the HD population in Italy, we set out to compare the whole EUCLID population with patients included in the regional HD registries in Emilia-Romagna (Northern Italy) and in Calabria (Southern Italy), the sole regions in Italy which have systematically collected an enlarged clinical data set allowing comparison with the data-rich EUCLID system...
February 16, 2017: Journal of Nephrology
https://www.readbyqxmd.com/read/28099636/use-of-reactive-hyperemia-peripheral-arterial-tonometry-and-circulating-biological-markers-to-predict-outcomes-in-sepsis
#2
Vandack Nobre, Thiago Bragança Ataíde, Luisa Caldeira Brant, Clara Rodrigues Oliveira, Lucas Vieira Rodrigues, Antonio Luiz Pinho Ribeiro, Fernanda Barbosa Lopes, Ivan Euclides Saraiva, Marcus Vinícius Andrade
Objective: To evaluate the usefulness and prognostic value of reactive hyperemia - peripheral arterial tonometry in patients with sepsis. Moreover, we investigated the association of reactive hyperemia - peripheral arterial tonometry results with serum levels of certain inflammatory molecules. Methods: Prospective study, conducted in an 18-bed mixed intensive care unit for adults. The exclusion criteria included severe immunosuppression or antibiotic therapy initiated more than 48 hours before assessment...
October 2016: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/28007880/residual-syntax-score-following-coronary-artery-bypass-grafting%C3%A2
#3
Giovanni Melina, Emiliano Angeloni, Simone Refice, Cristian Benegiamo, Andrea Lechiancole, Maria Matteucci, Antonino Roscitano, Roberto Bianchini, Fabio Capuano, Cosimo Comito, Pietro Spitaleri, Euclide Tonelli, Giulio Speciale, Christian Pristipino, Francesco Monti, Roberto Serdoz, Francesco Paneni, Riccardo Sinatra
OBJECTIVES: To quantify residual coronary artery disease measured using the SYNTAX score (SS) and its relation to outcomes after coronary artery bypass grafting (CABG). METHODS: We conducted a retrospective analysis on a consecutive series of 1608 patients [mean age 68 years, standard deviation (SD): 7, F:M, 242:1366] undergoing first-time isolated CABG from 2004 to 2015. The baseline SS was retrospectively determined from preoperative angiograms, and the residual SS (rSS) was measured during assessment of the actual operative report for each patient after CABG...
December 22, 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/27959717/ticagrelor-versus-clopidogrel-in-symptomatic-peripheral-artery-disease
#4
RANDOMIZED CONTROLLED TRIAL
William R Hiatt, F Gerry R Fowkes, Gretchen Heizer, Jeffrey S Berger, Iris Baumgartner, Peter Held, Brian G Katona, Kenneth W Mahaffey, Lars Norgren, W Schuyler Jones, Juuso Blomster, Marcus Millegård, Craig Reist, Manesh R Patel
Background Peripheral artery disease is considered to be a manifestation of systemic atherosclerosis with associated adverse cardiovascular and limb events. Data from previous trials have suggested that patients receiving clopidogrel monotherapy had a lower risk of cardiovascular events than those receiving aspirin. We wanted to compare clopidogrel with ticagrelor, a potent antiplatelet agent, in patients with peripheral artery disease. Methods In this double-blind, event-driven trial, we randomly assigned 13,885 patients with symptomatic peripheral artery disease to receive monotherapy with ticagrelor (90 mg twice daily) or clopidogrel (75 mg once daily)...
5, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/27933004/policy-implications-of-achievement-testing-using-multilevel-models-the-case-of-brazilian-elementary-schools
#5
Igor G Menezes, Victor R Duran, Euclides J Mendonça Filho, Tainã J Veloso, Stella M S Sarmento, Christine L Paget, Kai Ruggeri
Large-scale educational assessment has been established as source of descriptive, evaluative and interpretative information that influence educational policies worldwide throughout the last third of the twentieth century. In the 1990s the Brazilian Ministry of Education developed the National Basic Education Assessment System (SAEB) that regularly measures management, resource and contextual school features and academic achievement in public and private institutions. In 2005, after significant piloting and review of the SAEB, a new sampling strategy was taken and Prova Brasil became the new instrument used by the Ministry to assess skills in Portuguese (reading comprehension) and Mathematics (problem solving), as well as collecting contextual information concerning the school, principal, teacher, and the students...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27866182/homeopathic-treatment-of-overweight-and-obesity-in-pregnant-women-with-mental-disorders-a-double-blind-controlled-clinical-trial
#6
Edgard Costa de Vilhena, Euclides Ayres de Castilho
Context • Worldwide, 35 million people suffer from obesity. Mental disorders have been associated with being overweight or obese. Considerable evidence has shown a correlation between stress and the use of homeopathy and stress and obesity. However, few studies have examined the relationship between weight loss and homeopathic treatment of obesity. Objective • The study intended to evaluate the efficacy of a homeopathic treatment in preventing excessive weight gain during pregnancy in overweight or obese women who were suspected of having a common mental disorder...
October 2016: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/27847207/effect-of-patchouli-pogostemon-cablin-essential-oil-on-in-vitro-and-in-vivo-leukocytes-behavior-in-acute-inflammatory-response
#7
Saulo Euclides Silva-Filho, Luiz Alexandre Marques Wiirzler, Heitor Augusto Otaviano Cavalcante, Nancy Sayuri Uchida, Francielli Maria de Souza Silva-Comar, Gabriel Fernando Esteves Cardia, Expedito Leite da Silva, Rafael Pazinatto Aguiar, Ciomar Aparecida Bersani-Amado, Roberto Kenji Nakamura Cuman
PURPOSE: The aim of this study was to evaluate the effect of Pogostemon cablin essential oil (PEO) on leukocyte behavior in the inflammatory response. METHODS AND RESULTS: PEO was analyzed using Gas Chromatography/Mass Spectrometry (GC/SM) and Nuclear Magnetic Resonance Spectroscopy (NMR) methods and showed predominance of patchoulol (38.50%), α-bulnesene (20.37%), α-guaiene (12.31%), seychellene (8.33%) and α-patchoulene (4.91%). PEO at concentrations of 1, 3, 10, 30, 60 and 90μg/ml reduced the in vitro neutrophil chemotaxis toward fMLP, and at concentrations of 3 and 10μg/ml, increased the phagocytic activity of neutrophils...
December 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27834352/multistate-memristive-tantalum-oxide-devices-for-ternary-arithmetic
#8
Wonjoo Kim, Anupam Chattopadhyay, Anne Siemon, Eike Linn, Rainer Waser, Vikas Rana
Redox-based resistive switching random access memory (ReRAM) offers excellent properties to implement future non-volatile memory arrays. Recently, the capability of two-state ReRAMs to implement Boolean logic functionality gained wide interest. Here, we report on seven-states Tantalum Oxide Devices, which enable the realization of an intrinsic modular arithmetic using a ternary number system. Modular arithmetic, a fundamental system for operating on numbers within the limit of a modulus, is known to mathematicians since the days of Euclid and finds applications in diverse areas ranging from e-commerce to musical notations...
November 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27832772/calcitriol-stimulates-gene-expression-of-cathelicidin-antimicrobial-peptide-in-breast-cancer-cells-with-different-phenotype
#9
Janice García-Quiroz, Rocío García-Becerra, Nancy Santos-Martínez, Euclides Avila, Fernando Larrea, Lorenza Díaz
BACKGROUND: In normal and neoplastic cells, growth-promoting, proangiogenic, cytotoxic and pro-apoptotic effects have all been attributed to cathelicidin antimicrobial peptide (CAMP). Nevertheless, little is known about the factors regulating this peptide expression in breast cancer. Herein we asked if the well-known antineoplastic hormone calcitriol could differentially modulate CAMP gene expression in human breast cancer cells depending on the cell phenotype in terms of efficacy and potency...
November 10, 2016: Journal of Biomedical Science
https://www.readbyqxmd.com/read/27826826/integrated-monitoring-for-environmental-health-impact-assessment-related-to-the-genotoxic-effects-of-vehicular-pollution-in-uberl%C3%A3-ndia-brazil
#10
Boscolli Barbosa Pereira, Paolla Brandão da Cunha, Guilherme Gomes Silva, Edimar Olegário de Campos Júnior, Sandra Morelli, Cláudio Alves Vieira Filho, Euclides Antônio Pereira de Lima, Marcos Antônio Souza Barrozo
The development of parameters to explore the link between air-related diseases and their significant driving forces is an important aim in terms of national economics and public health. In this study, we did an integrated analysis involving multiple environmental health indicators from Uberlândia, Brazil, registered before and during a period when the Brazilian government reduced taxes on new cars in a bid to bolster local manufacturing. In addition, the present study utilized Driving Force-Pressure-State-Exposure-Effect-Action (DPSEEA) frameworks to evaluate correlations in environmental health indicators over 10 years (2004-2013), in which the Brazilian government reduced vehicle production taxes beginning in 2008...
November 8, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27805046/natural-resistance-to-meningococcal-disease-related-to-cfh-loci-meta-analysis-of-genome-wide-association-studies
#11
Federico Martinón-Torres, Eileen Png, Chiea Chuen Khor, Sonia Davila, Victoria J Wright, Kar Seng Sim, Ana Vega, Laura Fachal, David Inwald, Simon Nadel, Enitan D Carrol, Nazareth Martinón-Torres, Sonia Marcos Alonso, Angel Carracedo, Elvira Morteruel, Julio López-Bayón, Andrés Concha Torre, Cristina Calvo Monge, Pilar Azcón González de Aguilar, Elisabeth Esteban Torné, María Del Carmen Martínez-Padilla, José María Martinón-Sánchez, Michael Levin, Martin L Hibberd, Antonio Salas
Meningococcal disease (MD) remains an important infectious cause of life threatening infection in both industrialized and resource poor countries. Genetic factors influence both occurrence and severity of presentation, but the genes responsible are largely unknown. We performed a genome-wide association study (GWAS) examining 5,440,063 SNPs in 422 Spanish MD patients and 910 controls. We then performed a meta-analysis of the Spanish GWAS with GWAS data from the United Kingdom (combined cohorts: 897 cases and 5,613 controls; 4,898,259 SNPs)...
November 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27795572/the-development-of-euclidean-axiomatics-the-systems-of-principles-and-the-foundations-of-mathematics-in-editions-of-the-elements-in-the-early-modern-age
#12
Vincenzo De Risi
The paper lists several editions of Euclid's Elements in the Early Modern Age, giving for each of them the axioms and postulates employed to ground elementary mathematics.
2016: Archive for History of Exact Sciences
https://www.readbyqxmd.com/read/27701846/genetic-and-phytochemical-analysis-to-evaluate-the-diversity-and-relationships-of-mate-ilex-paraguariensis-a-st-hil-elite-genetic-resources-in-a-germplasm-collection
#13
Juliana Cristhina Friedrich, Adriana Gonela, Maria Celeste Gonçalves Vidigal, Pedro Soares Vidigal Filho, José Alfredo Sturion, Euclides Lara Cardozo
The aim of this study was to evaluate the phytochemical and genetic diversity, relationships and identification of mate (Ilex paraguariensis A. St.-Hil.) elite genetic resources belonging to the Brazilian germplasm collection and mate breeding program. Mate has been studied due to the presence of phytochemical compounds, especially methylxanthines and phenolic compounds. The samples were collected from the leaves of 76 mate elite genetic resources (16 progenies x 5 localities). Total DNA was extracted from mate leaves and twenty random primers were used for DNA amplification...
October 4, 2016: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/27689133/fuzzy-logic-for-incidence-geometry
#14
Alex Tserkovny
The paper presents a mathematical framework for approximate geometric reasoning with extended objects in the context of Geography, in which all entities and their relationships are described by human language. These entities could be labelled by commonly used names of landmarks, water areas, and so forth. Unlike single points that are given in Cartesian coordinates, these geographic entities are extended in space and often loosely defined, but people easily perform spatial reasoning with extended geographic objects "as if they were points...
2016: TheScientificWorldJournal
https://www.readbyqxmd.com/read/27659735/role-of-cephalosporins-in-the-era-of-clostridium-difficile-infection
#15
REVIEW
Mark H Wilcox, James D Chalmers, Carl E Nord, Jane Freeman, Emilio Bouza
The incidence of Clostridium difficile infection (CDI) in Europe has increased markedly since 2000. Previous meta-analyses have suggested a strong association between cephalosporin use and CDI, and many national programmes on CDI control have focused on reducing cephalosporin usage. Despite reductions in cephalosporin use, however, rates of CDI have continued to rise. This review examines the potential association of CDI with cephalosporins, and considers other factors that influence CDI risk. EUCLID (the EUropean, multicentre, prospective biannual point prevalence study of CLostridium difficile Infection in hospitalized patients with Diarrhoea) reported an increase in the annual incidence of CDI from 6...
January 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27639478/chronic-moderate-ethanol-intake-differentially-regulates-vitamin-d-hydroxylases-gene-expression-in-kidneys-and-xenografted-breast-cancer-cells-in-female-mice
#16
Janice García-Quiroz, Rocío García-Becerra, Galia Lara-Sotelo, Euclides Avila, Sofía López, Nancy Santos-Martínez, Ali Halhali, David Ordaz-Rosado, David Barrera, Andrea Olmos-Ortiz, María J Ibarra-Sánchez, José Esparza-López, Fernando Larrea, Lorenza Díaz
Factors affecting vitamin D metabolism may preclude anti-carcinogenic effects of its active metabolite calcitriol. Chronic ethanol consumption is an etiological factor for breast cancer that affects vitamin D metabolism; however, the mechanisms underlying this causal association have not been fully clarified. Using a murine model, we examined the effects of chronic moderate ethanol intake on tumoral and renal CYP27B1 and CYP24A1 gene expression, the enzymes involved in calcitriol synthesis and inactivation, respectively...
September 14, 2016: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/27546285/family-medicine-at-the-university-of-the-west-indies-a-model-for-the-developing-world
#17
Rohan G Maharaj, Aileen Standard-Goldson, Cherilyn Hanna-Mahase, Sonia Roache-Barker, Colette Cunningham-Myrie, M Shastri Motilal, Carnille Farquharson, Euclid Morris, Joanne Paul-Charles, Pauline Williams-Green, O Peter Adams
: Context and background: To describe the Family Medicine (FM) postgraduate training programme at the University of the West Indies (UWI). Actions and activities: This paper was created through a review of documents, and discussions with past and present coordinators and key stakeholders at four campuses in the English-speaking Caribbean (ESC). LESSONS LEARNED: Despite intermittent setbacks the FM programme in the ESC has grown due to: (1) The presence of an umbrella institution in the UWI...
September 2016: Education for Primary Care
https://www.readbyqxmd.com/read/27545581/nonlinear-metamaterials-for-holography
#18
Euclides Almeida, Ora Bitton, Yehiam Prior
A hologram is an optical element storing phase and possibly amplitude information enabling the reconstruction of a three-dimensional image of an object by illumination and scattering of a coherent beam of light, and the image is generated at the same wavelength as the input laser beam. In recent years, it was shown that information can be stored in nanometric antennas giving rise to ultrathin components. Here we demonstrate nonlinear multilayer metamaterial holograms. A background free image is formed at a new frequency-the third harmonic of the illuminating beam...
2016: Nature Communications
https://www.readbyqxmd.com/read/27470194/diversity-of-clostridium-difficile-pcr-ribotypes-in-europe-results-from-the-european-multicentre-prospective-biannual-point-prevalence-study-of-clostridium-difficile-infection-in-hospitalised-patients-with-diarrhoea-euclid-2012-and-2013
#19
Kerrie A Davies, Helen Ashwin, Christopher M Longshaw, David A Burns, Georgina L Davis, Mark H Wilcox
Clostridium difficile infection (CDI) is the major cause of infective diarrhoea in healthcare environments. As part of the European, multicentre, prospective, biannual, point-prevalence study of Clostridium difficile infection in hospitalised patients with diarrhoea (EUCLID), the largest C. difficile epidemiological study of its type, PCR ribotype distribution of C. difficile isolates in Europe was investigated. PCR ribotyping was performed on 1,196 C. difficile isolates from diarrhoeal samples sent to the European coordinating laboratory in 2012-13 and 2013 (from two sampling days) by 482 participating hospitals from 19 European countries...
July 21, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/27461462/in-situ-identification-of-pigment-composition-and-particle-size-on-wall-paintings-using-visible-spectroscopy-as-a-noninvasive-measurement-method
#20
Junfeng Li, Xiaoxia Wan, Yajing Bu, Chan Li, Jinxing Liang, Qiang Liu
Noninvasive examination methods of chemical composition and particle size are presented here based on visible spectroscopy to achieve the identification and recording of mineral pigments used on ancient wall paintings. The normalized spectral curve, slope and curvature extracted from visible spectral reflectance are combined with adjustable weighting coefficients to construct the identification feature space, and Euclid distances between spectral reflectance from wall paintings and a reference database are calculated in the feature space as the discriminant criterion to identify the chemical composition of mineral pigments...
July 26, 2016: Applied Spectroscopy
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