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https://www.readbyqxmd.com/read/29643372/good-and-bad-love-and-intimacy-from-plato-to-melanie-klein
#1
David Stromberg
Melanie Klein's theories on love outline a complex system of relations-an oscillating dynamic of psychical and emotional tendencies following from both actual experience and fantasies produced by the mind. Her insights are often discussed and applied in psychoanalytical contexts, but the philosophical implications of her theory-especially in relation to Platonic thought-have rarely been discussed. In this article, I will attempt to address this gap by setting out some preliminary yet core considerations shared by both Plato and Klein...
April 11, 2018: American Journal of Psychoanalysis
https://www.readbyqxmd.com/read/29606061/on-the-couch-a-repressed-history-of-the-analytic-couch-from-plato-to-freudby-nathan-kravis-m-d-cambridge-mass-mit-press-2017-224-pp-29-95-hardcover
#2
Ellen Blumenthal
No abstract text is available yet for this article.
April 1, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29602577/does-multimorbidity-still-remain-a-matter-of-the-elderly-lithuanian-national-data-analysis
#3
E Jurevičienė, G Onder, Ž Visockienė, R Puronaitė, D Petrikonytė, U Gargalskaitė, V Kasiulevičius, R Navickas
INTRODUCTION: Multimorbidity - the coexistence of ≥2 chronic conditions in same individual is usually associated with older age. There is an increase in its prevalence at a much younger age, however with very limited research specifying that. OBJECTIVE: To identify age breaking points for the occurrence of multimorbidity. METHODS: The study included patients, who used any healthcare services between the 01/01/2012 and 30/06/2014. Patients were divided into two groups - with single chronic condition and with multimorbidity...
March 14, 2018: Health Policy
https://www.readbyqxmd.com/read/29589321/a-history-and-overview-of-the-behavioral-neuroscience-of-learning-and-memory
#4
Robert E Clark
Here, I provide a basic history of important milestones in the development of theories for how the brain accomplishes the phenomenon of learning and memory. Included are the ideas of Plato, René Descartes, Théodule Ribot, William James, Ivan Pavlov, John Watson, Karl Lashley, and others. The modern era of learning and memory research begins with the description of H.M. by Brenda Milner and the gradual discovery that the brain contains multiple learning and memory systems that are supported by anatomically discrete brain structures...
2018: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/29525297/hysteria-in-ancient-civilisations-a-neurological-review-possible-significance-for-the-modern-disorder
#5
REVIEW
Edward H Reynolds
The word hysteria originated in the Corpus Hippocraticum (c420 BCE) as a natural explanation for a variety of diseases in women linked in the Greco-Roman mind to an animate or inanimate womb, but which in the last five centuries has evolved to describe an elusive disorder of brain ± mind in men and women, currently referred to by neurologists as "functional neurological disorder". The Babylonians, Assyrians and Egyptians had no knowledge of brain or psychological function. Babylonian and Assyrian descriptions of disease and behaviour include only rare examples suggestive of modern hysteria...
February 17, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29516318/on-the-couch-a-repressed-history-of-the-analytic-couch-from-plato-to-freud-by-nathan-kravis-mit-press-2017-lccn-2016052900-isbn-9780262036610
#6
Kimberly Bloom-Feshbach
No abstract text is available yet for this article.
March 7, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29489751/recognition-of-dhn-melanin-by-a-c-type-lectin-receptor-is-required-for-immunity-to-aspergillus
#7
Mark H T Stappers, Alexandra E Clark, Vishukumar Aimanianda, Stefan Bidula, Delyth M Reid, Patawee Asamaphan, Sarah E Hardison, Ivy M Dambuza, Isabel Valsecchi, Bernhard Kerscher, Anthony Plato, Carol A Wallace, Raif Yuecel, Betty Hebecker, Maria da Glória Teixeira Sousa, Cristina Cunha, Yan Liu, Ten Feizi, Axel A Brakhage, Kyung J Kwon-Chung, Neil A R Gow, Matteo Zanda, Monica Piras, Chiara Zanato, Martin Jaeger, Mihai G Netea, Frank L van de Veerdonk, João F Lacerda, António Campos, Agostinho Carvalho, Janet A Willment, Jean-Paul Latgé, Gordon D Brown
Resistance to infection is critically dependent on the ability of pattern recognition receptors to recognize microbial invasion and induce protective immune responses. One such family of receptors are the C-type lectins, which are central to antifungal immunity. These receptors activate key effector mechanisms upon recognition of conserved fungal cell-wall carbohydrates. However, several other immunologically active fungal ligands have been described; these include melanin, for which the mechanism of recognition is hitherto undefined...
February 28, 2018: Nature
https://www.readbyqxmd.com/read/29489632/temporal-immediacy-a-two-system-theory-of-mind-for-understanding-and-changing-health-behaviors
#8
Paul F Cook, Sarah J Schmiege, Blaine Reeder, Sara Horton-Deutsch, Nancy K Lowe, Paula Meek
BACKGROUND: Health promotion and chronic disease management both require behavior change, but people find it hard to change behavior despite having good intentions. The problem arises because patients' narratives about experiences and intentions are filtered through memory and language. These narratives inaccurately reflect intuitive decision-making or actual behaviors. OBJECTIVES: We propose a principle-temporal immediacy-as a moderator variable that explains which of two mental systems (narrative or intuitive) will be activated in any given situation...
March 2018: Nursing Research
https://www.readbyqxmd.com/read/29488142/safety-and-incidence-of-cardiovascular-events-in-chinese-patients-with-acute-coronary-syndrome-treated-with-ticagrelor-the-12-month-phase-iv-multicenter-single-arm-dayu-study
#9
Runlin Gao, Yongjian Wu, Hengliang Liu, Guohai Su, Zuyi Yuan, Aidong Zhang, Yong Wang, Zhirong Wang, Yan Wang, Huanyi Zhang, Yang Zheng, Lei Liu, Lijun Shen, Maria Leonsson-Zachrisson, Yaling Han
PURPOSE: Ticagrelor is an orally administered, reversibly binding, direct-acting P2Y12 receptor antagonist previously evaluated in several phase III trials. This phase IV, multicenter, single-arm trial assessed the safety and incidence of cardiovascular (CV) events with ticagrelor in Chinese patients experiencing an acute coronary syndrome (ACS). METHODS: Patients hospitalized with an ACS received ticagrelor (180 mg loading dose, 90 mg twice daily thereafter) plus low-dose aspirin (75-100 mg/day) for up to 12 months...
February 28, 2018: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29452843/ticagrelor-versus-clopidogrel-in-east-asian-patients-with-acute-coronary-syndrome-systematic-review-and-meta-analysis
#10
Naoki Misumida, Shunsuke Aoi, Sun Moon Kim, Khaled M Ziada, Ahmed Abdel-Latif
BACKGROUND: Bleeding complications are associated with unfavorable outcomes in patients with acute coronary syndrome (ACS). Compared to Whites, several studies demonstrated a higher risk of bleeding in Asians who present with acute myocardial infarction. To date, the efficacy and safety of ticagrelor in East Asian population have not been well established. METHODS: We conducted a systematic review and meta-analysis of randomized controlled trials that compared ticagrelor and clopidogrel in East Asian patients with acute coronary syndrome (ACS)...
January 31, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29443375/ischaemic-events-and-stent-thrombosis-following-planned-discontinuation-of-study-treatment-with-ticagrelor-or-clopidogrel-in-the-plato-study
#11
Robert F Storey, Diego Ardissino, Luigi Vignali, Richard Cairns, Richard C Becker, Christopher P Cannon, Kenneth W Mahaffey, Anders Himmelmann, Hugo A Katus, Stefan K James, Lars Wallentin
No abstract text is available yet for this article.
February 2018: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29390064/fibrin-clot-properties-independently-predict-adverse-clinical-outcome-following-acute-coronary-syndrome-a-plato-substudy
#12
Wael Sumaya, Lars Wallentin, Stefan K James, Agneta Siegbahn, Katja Gabrysch, Maria Bertilsson, Anders Himmelmann, Ramzi A Ajjan, Robert F Storey
Aims: To determine whether fibrin clot properties are associated with clinical outcomes following acute coronary syndrome (ACS). Methods and results: Plasma samples were collected at hospital discharge from 4354 ACS patients randomized to clopidogrel or ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial. A validated turbidimetric assay was employed to study plasma clot lysis time and maximum turbidity (a measure of clot density). One-year rates of cardiovascular (CV) death, spontaneous myocardial infarction (MI) and PLATO-defined major bleeding events were assessed after sample collection...
January 29, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29384027/an-evaluation-of-the-cost-effectiveness-of-comprehensive-mtm-integrated-with-point-of-care-phenotypic-and-genetic-testing-for-u-s-elderly-patients-after-percutaneous-coronary-intervention
#13
Arinze Nkemdirim Okere, Kyrian Ezendu, Abdrahmane Berthe, Vakaramoko Diaby
BACKGROUND: Poor health outcomes after percutaneous coronary intervention (PCI) in elderly patients is an area of concern among policymakers and administrators. In an effort to determine the best strategy to improve outcomes among elderly patients who underwent PCI, several studies have evaluated the cost-effectiveness of genotype-guided antiplatelet therapy compared with universal use of any one of the antiplatelet drugs indicated for patients with acute coronary syndrome (ACS) who underwent PCI...
February 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29344910/mimesis-and-clinical-pictures-thinking-with-plato-and-broekman-through-the-production-and-meaning-of-images-of-disease
#14
Marjolein Oele
This paper contends, following Plato and Broekman, that (1) seeing images as images is crucial to theorizing medicine and that (2) considering clinical pictures as images of images is a much-needed epistemic complement to the domineering view that sees clinical pictures as mirrors of disease. This does not only offer epistemic, but also ethical benefits to individual patients, especially in those cases where patients suffer from chronic, debilitating, and terminal illnesses and where medicine provides no, or limited, answers in terms of treatment, intervention, and meaning...
January 17, 2018: Medicine, Health Care, and Philosophy
https://www.readbyqxmd.com/read/29330256/osteoprotegerin-is-associated-with-major-bleeding-but-not-with-cardiovascular-outcomes-in-patients-with-acute-coronary-syndromes-insights-from-the-plato-platelet-inhibition-and-patient-outcomes-trial
#15
Thor Ueland, Axel Åkerblom, Tatevik Ghukasyan, Annika E Michelsen, Pål Aukrust, Richard C Becker, Maria Bertilsson, Anders Himmelmann, Stefan K James, Agneta Siegbahn, Robert F Storey, Frederic Kontny, Lars Wallentin
BACKGROUND: Elevated levels of osteoprotegerin, a secreted tumor necrosis factor-related molecule, might be associated with adverse outcomes in patients with coronary artery disease. We measured plasma osteoprotegerin concentrations on hospital admission, at discharge, and at 1 and 6 months after discharge in a predefined subset (n=5135) of patients with acute coronary syndromes in the PLATO (Platelet Inhibition and Patient Outcomes) trial. METHODS AND RESULTS: The associations between osteoprotegerin and the composite end point of cardiovascular death, nonprocedural spontaneous myocardial infarction or stroke, and non-coronary artery bypass grafting major bleeding during 1 year of follow-up were assessed by Cox proportional hazards models...
January 12, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29302901/a-history-and-overview-of-the-behavioral-neuroscience-of-learning-and-memory
#16
Robert E Clark
Here, I provide a basic history of important milestones in the development of theories for how the brain accomplishes the phenomenon of learning and memory. Included are the ideas of Plato, René Descartes, Théodule Ribot, William James, Ivan Pavlov, John Watson, Karl Lashley, and others. The modern era of learning and memory research begins with the description of H.M. by Brenda Milner and the gradual discovery that the brain contains multiple learning and memory systems that are supported by anatomically discrete brain structures...
January 5, 2018: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/29299702/robot-life-simulation-and-participation-in-the-study-of-evolution-and-social-behavior
#17
Christopher M Kelty
This paper explores the case of using robots to simulate evolution, in particular the case of Hamilton's Law. The uses of robots raises several questions that this paper seeks to address. The first concerns the role of the robots in biological research: do they simulate something (life, evolution, sociality) or do they participate in something? The second question concerns the physicality of the robots: what difference does embodiment make to the role of the robot in these experiments. Thirdly, how do life, embodiment and social behavior relate in contemporary biology and why is it possible for robots to illuminate this relation? These questions are provoked by a strange similarity that has not been noted before: between the problem of simulation in philosophy of science, and Deleuze's reading of Plato on the relationship of ideas, copies and simulacra...
January 3, 2018: History and Philosophy of the Life Sciences
https://www.readbyqxmd.com/read/29275804/from-circe-s-root-to-spongia-soporifera-the-role-of-the-mandrake-as-true-anesthetic-of-ancient-times
#18
Marta Mion
Several ancient authors cited mandrake as a powerful and well-known narcotic drug: from Homer to Dioscorides, from Plato to Aristotle, passing from Hippocrates, Demosthenes, Theophrastus, Celsus, and Apuleius. Their detailed studies included the concrete appearance of the plant, the related recipes including mandrake as essential ingredient, the right dosages, how to administer the obtained medication, and the possible collateral effects. Even in the Middle Ages, the success of this root continued: Isidore of Seville, Theodoric of Cervia, Gilbertus Anglicus, and William from Varignana extensively reported their researches on sponges soaked with mandrake juice, which were used before surgical interventions as soporific tools...
October 2017: Journal of Anesthesia History
https://www.readbyqxmd.com/read/29249867/reflection-a-socratic-approach
#19
Inge C M Van Seggelen-Damen, René Van Hezewijk, Anne S Helsdingen, Iwan G J H Wopereis
Reflection is a fuzzy concept. In this article we reveal the paradoxes involved in studying the nature of reflection. Whereas some scholars emphasize its discursive nature, we go further and underline its resemblance to the self-biased dialogue Socrates had with the slave in Plato's Meno . The individual and internal nature of the reflection process creates difficulty for studying it validly and reliably. We focus on methodological issues and use Hans Linschoten's view of coupled systems to identify, analyze, and interpret empirical research on reflection...
December 2017: Theory & Psychology
https://www.readbyqxmd.com/read/29241289/-radiology-in-the-light-of-evolutionary-cognitive-theory
#20
Paul Gelinsky
An X-ray photograph is not adapted to the human a priori intuition: it is not colored, it is two-dimensional, has no depth and no perspective. A radiograph is composed by about 100 gradations of grey, of which the human eye cannot resolve more than 30. Projection radiography has a cardinal problem: the superposition of normal and pathological structures. Apart from visual physiology, visual psychology plays an essential role in diagnosis: expectation and stereotyped thinking influence the interpretation of visual perception...
December 2017: Deutsche Medizinische Wochenschrift
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