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https://www.readbyqxmd.com/read/29150380/comparison-of-two-physiotherapy-programmes-for-rehabilitation-after-temporomandibular-joint-arthroscopy
#1
W A Abboud, N Yarom, R Yahalom, M Joachim, S Reiter, O Koren, H Elishoov
The purpose of this study was to compare two physiotherapy programmes for rehabilitation after temporomandibular joint (TMJ) arthroscopy. The medical files of 137 consecutive patients diagnosed with closed lock and treated by arthroscopic lysis and lavage were analyzed retrospectively. Sixty-eight patients were rehabilitated with gradually increasing range of motion self-exercises (gradual programme) and 69 patients were rehabilitated with immediate full range of motion self-exercises (immediate programme)...
November 14, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29150077/unique-arginine-array-improves-cytosolic-localization-of-hydrocarbon-stapled-peptides
#2
Kim Quach, Jonathan LaRochelle, Xiao-Han Li, Elizabeth Rhoades, Alanna Schepartz
We have previously reported that miniature proteins containing a distinct array of 5 arginine residues on a folded α-helix - a penta-arg motif - traffic with high efficiency from endosomes into the cytosol and nucleus of mammalian cells. Here we evaluate whether a penta-arg motif can improve the intracellular trafficking of an otherwise impermeant hydrocarbon-stapled peptide, SAH-p53-4(Rho). We prepared a panel of SAH-p53-4(Rho) variants containing penta-arg sequences with different spacings and axial arrangement and evaluated their overall uptake (as judged by flow cytometry) and their intracellular access (as determined by fluorescence correlation spectroscopy, FCS)...
November 7, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/29149494/inhibiting-mt2-tfe3-dependent-autophagy-enhances-melatonin-induced-apoptosis-in-tongue-squamous-cell-carcinoma
#3
Tengfei Fan, Huifeng Pi, Min Li, Zhenhu Ren, Zhijing He, Feiya Zhu, Li Tian, Manyu Tu, Jia Xie, Mengyu Liu, Yuming Li, Miduo Tan, Gaoming Li, Weijia Qing, Russel J Reiter, Zhengping Yu, Hanjiang Wu, Zhou Zhou
Autophagy modulation is a potential therapeutic strategy for tongue squamous cell carcinoma (TSCC). Melatonin possesses significant anti-carcinogenic activity. However, whether melatonin induces autophagy and its roles in cell death in TSCC are unclear. Herein, we show that melatonin induced significant apoptosis in the TSCC cell line Cal27. Apart from the induction of apoptosis, we demonstrated that melatonin-induced autophagic flux in Cal27 cells as evidenced by the formation of GFP-LC3 puncta, and the upregulation of LC3-II and downregulation of SQSTM1/P62...
November 17, 2017: Journal of Pineal Research
https://www.readbyqxmd.com/read/29149482/melatonin-alleviates-low-ps-i-limited-carbon-assimilation-under-elevated-co2-and-enhances-the-cold-tolerance-of-offspring-in-chlorophyll-b-deficient-mutant-wheat
#4
Xiangnan Li, Marian Brestic, Dun-Xian Tan, Marek Zivcak, Xiancan Zhu, Shengqun Liu, Fengbin Song, Russel J Reiter, Fulai Liu
Melatonin is involved in the regulation of carbohydrate metabolism and induction of cold tolerance in plants. The objective of this study was to investigate the roles of melatonin in modulation of carbon assimilation of wild type wheat and the Chl b-deficient mutant ANK32B in response to elevated CO2 concentration ([CO2 ]) and the transgenerational effects of application of exogenous melatonin (hereafter identified as melatonin priming) on the cold tolerance in offspring. The results showed that the melatonin priming enhanced the carbon assimilation in ANK32B under elevated [CO2 ], via boosting the activities of ATPase and sucrose synthesis and maintaining a relatively higher level of total chlorophyll concentration in leaves...
November 17, 2017: Journal of Pineal Research
https://www.readbyqxmd.com/read/29148409/a-high-and-equal-prevalence-of-the-q703k-variant-in-nlrp3-patients-with-autoinflammatory-symptoms-and-ethnically-matched-controls
#5
Merav Lidar, Yael Brantz, Yael Shinar, Haike Reznik-Wolf, Avi Livneh, Ilan Ben Zvi, Rinat Cohen, Yaakov Berkun, Philip J Hashkes, Hagit Peleg, Aharon Kessel, Gleb Slobodin, Michael Rozenbaum, Ofra Goldzweig, Elon Pras
OBJECTIVES: Cryopyrin associated periodic syndromes (CAPS) comprise a spectrum of autoinflammatory disorders of varying severity caused by mutations in the NLRP3 gene. The NLRP3-Q703K allele has been reported both as a functional polymorphism and as a low penetrance mutation. METHODS: To describe the clinical phenotype of subjects with the Q703K allele and to report the frequency of this allele among patients with autoinflammatory symptoms and healthy controls. To this end, a cohort of 10 ethnically-matched controls per each Q703K-carrying patient, was composed...
October 6, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29136773/the-potential-use-of-melatonin-to-treat-protozoan-parasitic-infections-a-review
#6
REVIEW
Ahmad Daryani, Mahbobeh Montazeri, Abdol Satar Pagheh, Mehdi Sharif, Shahabeddin Sarvi, Azam Hosseinzadeh, Russel J Reiter, Ramtin Hadighi, Mohammad Taghi Joghataei, Habib Ghaznavi, Saeed Mehrzadi
Melatonin (N-acetyl-5-methoxytryptamine) is a circadian hormone produced in vertebrates by the pineal gland and other organs. Melatonin is believed to influence immune cells leading to modulation of the proliferative response of stimulated lymphocytes as well as cytokine production. Due to the antioxidant and immunomodulatory effects of melatonin, it is suggested that this molecule could be a therapeutic alternative agent to fight bacterial, viral, and parasitic infections by a variety of mechanisms. Herein, we review the effects of melatonin on the cell biology of protozoan parasites and host's immune response...
November 7, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29135378/same-sex-parenting-identification-of-social-representations-in-a-sample-of-portuguese-professionals
#7
Paula Xavier, Isabel Alberto, Francisco Mendes
Although international scientific research and the position of professional associations reiterate that the parents' sexual orientation is not a criterion of parenting quality, the social recognition of same-sex parenting remains difficult in Portugal. Given the importance of forensic issues in this field, this study aims to identify the representations of psychologists, social workers, lawyers/attorneys, and judges regarding same-sex parenting. The study involves five homogeneous focus groups with a total of 19 professionals...
November 14, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/29135050/belief-about-mandatory-school-vaccinations-and-vaccination-refusal-among-ohio-appalachian-parents-do-demographic-and-religious-factors-general-health-and-political-affiliation-play-a-role
#8
Jessica L Krok-Schoen, Brittany M Bernardo, Rory C Weier, Juan Peng, Mira L Katz, Paul L Reiter, Morgan S Richardson, Michael L Pennell, Cathy M Tatum, Electra D Paskett
PURPOSE: To examine how demographic, general health, religious, and political characteristics influenced beliefs about mandatory school vaccinations and history of vaccination refusal for children among Ohio Appalachian parents. METHODS: In 2013 and 2014, baseline data were obtained from parents (n = 337) of girls aged 9-17 from 12 counties in rural Ohio Appalachia enrolled in the Community Awareness, Resources and Education (CARE II) Project. Multivariate logistic regression models were used to identify correlates of parental beliefs about mandatory school vaccinations and history of refusing a doctor-recommended vaccine for their child(ren)...
November 14, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/29133641/simultaneous-use-of-amniotic-membrane-and-mitomycin-c-in-trabeculectomy-for-primary-glaucoma
#9
Usha Yadava, Kirti Jaisingh, Sonal Dangda, Prolima Thacker, Kirti Singh, Yashpal Goel
PURPOSE: This study aimed to propose the role of amniotic membrane transplantation (AMT) as an additional modulator in primary Mitomycin C (MMC)-augmented trabeculectomy. METHODS: This was a randomized prospective interventional study. Forty eyes of 39 adult patients with uncontrolled primary glaucoma were randomly divided into two equal groups. Control group underwent trabeculectomy augmented with MMC while the study group underwent additional AMT. Patients were followed up for 12 months and outcomes measured were intraocular pressure (IOP), need for additional intervention, and bleb morphology...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29132787/distal-biceps-brachii-tendon-transfer-for-re-establishing-extrinsic-finger-function-feasibility-study-in-cadavers
#10
Matthew D Welsch, Alexander D Mih, Brock D Reiter, Gregory A Merrell
PURPOSE: To determine the anatomic feasibility of transferring the biceps brachii tendon into either the extensor digitorum communis (EDC) or flexor digitorum profundus (FDP), determine the excursion imparted to EDC and FDP tendons after transfer, and compare the work capacity of the cadaver biceps to previously published data on the biceps as well as the recipient muscles by calculating the physiologic cross-sectional area (PCSA). METHODS: Four fresh-frozen cadaver shoulder-elbow-wrist specimens were used to measure tendon excursion that can be obtained with transfer of the distal biceps tendon into either the EDC or FDP...
November 11, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29132182/-rare-case-of-a-blunt-cervical-sports-related-trauma-in-a-young-patient
#11
Ricarda Riepl, Thomas Karl Hoffmann, Rudolf Reiter, Melanie Nordmann, Bettina Ammann, Nicole Rotter
No abstract text is available yet for this article.
November 13, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/29131355/interaction-of-albumins-and-heparinoids-investigated-by-affinity-capillary-electrophoresis-and-free-flow-electrophoresis
#12
Mona Mozafari, Sami El Deeb, Friederike Krull, Robert Wildgruber, Gerhard Weber, Christian G Reiter, Hermann Wätzig
A fast and precise affinity capillary electrophoresis (ACE) method has been applied to investigate the interactions between two serum albumins (HSA and BSA) and heparinoids. Furthermore, different free flow electrophoresis methods were developed to separate the species which appears owing to interaction of albumins with pentosan polysulfate sodium (PPS) under different experimental conditions. For ACE experiments, the normalized mobility ratios (∆R/Rf ), which provided information about the binding strength and the overall charge of the protein-ligand complex, were used to evaluate the binding affinities...
November 13, 2017: Electrophoresis
https://www.readbyqxmd.com/read/29128577/pathological-and-3-tesla-volumetric-mr-predictors-of-biochemical-recurrence-after-robotic-assisted-radical-prostatectomy-correlation-with-whole-mount-histopathology
#13
Nelly Tan, Luyao Shen, Pooria Khoshnoodi, Héctor E Alcalá, Weixia Yu, William Hsu, Robert E Reiter, David Y Lu, Steven S Raman
OBJECTIVE: To identify the clinical and MRI variables predictive of biochemical recurrence (BCR) after robotic assisted radical prostatectomy (RALP) in patients who underwent multi-parametric 3 Tesla prostate MR Imaging. METHODS: An IRB approved, HIPAA compliant, a single arm observational study with 3T mpMRI prior to RALP from December 2009 until March 2016 was performed. Clinical, MRI, pathological information and clinical outcome were compiled. Biochemical recurrence was defined as PSA greater > 0...
November 8, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29127507/influence-of-coupler-size-on-revision-rate-and-timing-of-revision-after-free-flap-tissue-transfer-in-the-head-and-neck
#14
Ulrich Kisser, Christine Adderson-Kisser, Philipp Baumeister, Maximilian Reiter
OBJECTIVE: Microvascular coupler devices have been proven an effective alternative to standard hand-sutured anastomoses in reconstructive surgery. Until now, the influence of the coupler size on the revision rate after free flap tissue transfer in head and neck surgery has not been investigated. Neither has its influence on the timing of venous revisions. MATERIALS AND METHODS: A retrospective mono-center cohort study was performed in order to analyze the influence of coupler size on timing and revision rate of microvascular procedures...
November 10, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29126761/mr-planimetry-in-neurodegenerative-parkinsonism-yields-high-diagnostic-accuracy-for-psp
#15
Stephanie Mangesius, Anna Hussl, Florian Krismer, Philipp Mahlknecht, Eva Reiter, Susanne Tagwercher, Atbin Djamshidian, Michael Schocke, Regina Esterhammer, Gregor Wenning, Christoph Müller, Christoph Scherfler, Elke R Gizewski, Werner Poewe, Klaus Seppi
INTRODUCTION: Several previous studies examined different brainstem-derived MR planimetric measures with regards to their diagnostic accuracy in separating patients with neurodegenerative parkinsonian disorders and reported conflicting results. The current study aimed to compare their performance in a well-characterized sample of patients with neurodegenerative parkinsonian disorders. METHODS: MR planimetric measurements were assessed in a large retrospective cohort of 55 progressive supranuclear palsy (PSP), 194 Parkinson's disease (PD) and 63 multiple system atrophy (MSA) patients...
October 31, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29126423/the-many-meanings-of-evidence-a-comparative-analysis-of-the-forms-and-roles-of-evidence-within-three-health-policy-processes-in-cambodia
#16
Helen Walls, Marco Liverani, Kannarath Chheng, Justin Parkhurst
BACKGROUND: Discussions within the health community routinely emphasise the importance of evidence in informing policy formulation and implementation. Much of the support for the evidence-based policy movement draws from concern that policy decisions are often based on inadequate engagement with high-quality evidence. In many such discussions, evidence is treated as differing only in quality, and assumed to improve decisions if it can only be used more. In contrast, political science scholars have described this as an overly simplistic view of the policy-making process, noting that research 'use' can mean a variety of things and relies on nuanced aspects of political systems...
November 10, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/29126331/-a-rare-differential-diagnosis-of-supraglottic-oedema
#17
Natalie Fischer, Günter Weiss, Patrizia Moser, Afschin Soleiman, Alois Reiterer, Daniel Dejaco, Herbert Riechelmann
No abstract text is available yet for this article.
November 10, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/29124739/psychological-stress-and-psoriasis-a-systematic-review-and-meta-analysis
#18
REVIEW
I Snast, O Reiter, L Atzmony, Y A Leshem, E Hodak, D Mimouni, L Pavlovsky
BACKGROUND: Psychological stress has long been linked with psoriasis exacerbation/onset. However, it is unclear if they are associated. OBJECTIVE: To determine if antecedent psychological stress and psoriasis exacerbation/onset are associated. METHODS: A comprehensive search of Pubmed, PsycINFO, Cochrane library, and clinicaltrials. gov databases was performed. Studies investigating the association between preceding psychological stress and psoriasis exacerbation/onset were classified as cross-sectional, case-control or cohort...
November 9, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/29123324/three-decades-of-landsat-derived-spring-surface-water-dynamics-in-an-agricultural-wetland-mosaic-implications-for-migratory-shorebirds
#19
Danica Schaffer-Smith, Jennifer J Swenson, Blake Barbaree, Matthew E Reiter
Satellite measurements of surface water offer promise for understanding wetland habitat availability at broad spatial and temporal scales; reliable habitat is crucial for the persistence of migratory shorebirds that depend on wetland networks. We analyzed water extent dynamics within wetland habitats at a globally important shorebird stopover site for a 1983-2015 Landsat time series, and evaluated the effect of climate on water extent. A range of methods can detect open water from imagery, including supervised classification approaches and thresholds for spectral bands and indices...
May 2017: Remote Sensing of Environment
https://www.readbyqxmd.com/read/29123012/prostate-cancer-molecular-imaging-standardized-evaluation-promise-proposed-mitnm-classification-for-the-interpretation-of-psma-ligand-pet-ct
#20
Matthias Eiber, Ken Herrmann, Jeremie Calais, Boris Hadaschihk, Frederik L Giesel, Markus Hartenbach, Thomas Hope, Robert Reiter, Tobias Maurer, Wolfgang A Weber, Wolfgang P Fendler
Prostate-specific membrane antigen (PSMA)-ligand positron emission tomography (PET)-imaging provides unprecedented accuracy for whole body staging of prostate cancer. As PSMA-ligand PET/computed tomography (CT) is increasingly adopted in clinical trials and routine practice worldwide, a unified language for image reporting is urgently needed. We propose a molecular imaging tumor, node and metastasis system (miTNM Version 1.0) as standardized reporting framework for PSMA-ligand PET/CT or PET/magnetic resonance imaging (MRI)...
November 9, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
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