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CD203c omalizumab

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https://www.readbyqxmd.com/read/26725153/lack-of-basophil-cd203c-upregulating-activity-as-an-immunological-marker-to-predict-response-to-treatment-with%C3%A2-omalizumab-in-patients-with-symptomatic-chronic-urticaria
#1
Thamiris Palacios, Leland Stillman, Larry Borish, Monica Lawrence
No abstract text is available yet for this article.
May 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/25230301/carboplatin-induced-severe-hypersensitivity-reaction-role-of-ige-dependent-basophil-activation-and-fc%C3%AE%C2%B5ri
#2
Takuya Iwamoto, Hiroyuki Hirai, Nozomi Yamaguchi, Natsuki Kobayashi, Hiroko Sugimoto, Tsutomu Tabata, Masahiro Okuda
Basophil activation was observed in patients with a history of carboplatin-induced severe hypersensitivity reaction (HR). However, the precise mechanism by which carboplatin induces basophil activation and the associated surrogate markers remains to be elucidated. To investigate whether IgE-dependent mechanisms, including the overexpression of FcεRI, participate in carboplatin-induced basophil activation, 13 ovarian cancer patients were enrolled: 5 with a history of carboplatin-induced severe hypersensitivity reaction within the past 2 years, and 8 with no such history...
November 2014: Cancer Science
https://www.readbyqxmd.com/read/20975283/basophil-cd203c-levels-are-increased-at-baseline-and-can-be-used-to-monitor-omalizumab-treatment-in-subjects-with-nut-allergy
#3
Yael Gernez, Rabindra Tirouvanziam, Grace Yu, Eliver E B Ghosn, Neha Reshamwala, Tammie Nguyen, Mindy Tsai, Stephen J Galli, Leonard A Herzenberg, Leonore A Herzenberg, Kari C Nadeau
RATIONALE: Basophils contribute to anaphylaxis and allergies. We examined the utility of assessing basophil-associated surface antigens (CD11b/CD63/CD123/CD203c/CD294) in characterizing and monitoring subjects with nut allergy. METHODS: We used flow cytometry to analyze basophils at baseline (without any activation) and after ex vivo stimulation of whole blood by addition of nut or other allergens for 2, 10, and 30 min. We also evaluated whether basophil expression of CD11b/CD63/CD123/CD203c/CD294 was altered in subjects treated with anti-IgE monoclonal antibody (omalizumab) to reduce plasma levels of IgE...
2011: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/16436137/basophil-allergen-threshold-sensitivity-a-useful-approach-to-anti-ige-treatment-efficacy-evaluation
#4
COMPARATIVE STUDY
A Nopp, S G O Johansson, J Ankerst, G Bylin, L O Cardell, R Grönneberg, K Irander, M Palmqvist, H Oman
BACKGROUND: Monitoring of the allergen sensitivity of a patient is most important for optimal patient care and a basic prerequisite for immunomodulating treatment. The objective of this study was to investigate how basophil allergen sensitivity can be applied in the monitoring of anti-immunoglobulin E (IgE) treatment. METHODS: Basophils from timothy grass pollen allergic patients were, by flow cytometry, analysed for allergen threshold sensitivity (CD-sens) by measuring CD63 up-regulation on CD203c-identified basophils...
March 2006: Allergy
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