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https://www.readbyqxmd.com/read/28079901/the-clinical-utility-of-dna-based-screening-for-fetal-aneuploidy-by-primary-obstetrical-care-providers-in-the-general-pregnancy-population
#1
Glenn E Palomaki, Edward M Kloza, Barbara M O'Brien, Elizabeth E Eklund, Geralyn M Lambert-Messerlian
OBJECTIVE: To assess the clinical utility of cell-free DNA (cfDNA)-based screening for aneuploidies offered through primary obstetrical care providers to a general pregnancy population. METHODS: Patient educational materials were developed and validated and providers were trained. Serum was collected for reflexive testing of cfDNA failures. Providers and patients were surveyed concerning knowledge, decision making, and satisfaction. Pregnancy outcome was determined by active or passive ascertainment...
January 12, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28054570/socioeconomic-differences-in-prevalence-awareness-control-and-self-management-of-hypertension-among-four-minority-ethnic-groups-na-xi-li-shu-dai-and-jing-po-in-rural-southwest-china
#2
L Cai, J Dong, W L Cui, D Y You, A R Golden
This study investigates socioeconomic differences in prevalence, awareness, control and self-management of hypertension in rural China. A cross-sectional survey was conducted among four ethnic minority groups in Yunnan Province: Na Xi, Li Shu, Dai and Jing Po. Approximately 5532 consenting individuals aged ⩾35 years (48.4% of whom were male) were selected to participate in the study using a stratified, multistage sampling technique. Information about participants' demographic characteristics and hypertension awareness, treatment, control and self-management practices was obtained using a standard questionnaire...
January 5, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28032150/ocular-pain-and-impending-blindness-during-facial-cosmetic-injections-is-your-office-prepared
#3
Giselle Prado, Jose Rodríguez-Feliz
: Soft tissue filler injections are the second most common non-surgical procedure performed by the plastic surgeon. Embolization of intravascular material after facial injection is a rare but terrifying outcome due to the high likelihood of long-term sequela such as blindness and cerebrovascular accident. The literature is replete with examples of permanent blindness caused by injection with autologous fat, soft tissue fillers such as hyaluronic acid, PLLA, calcium hydroxyl-apatite, and even corticosteroid suspensions...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28027333/personalized-prescription-feedback-using-routinely-collected-data-to-reduce-antibiotic-use-in-primary-care-a-randomized-clinical-trial
#4
Lars G Hemkens, Ramon Saccilotto, Selene Leon Reyes, Dominik Glinz, Thomas Zumbrunn, Oliver Grolimund, Viktoria Gloy, Heike Raatz, Andreas Widmer, Andreas Zeller, Heiner C Bucher
Importance: Feedback interventions using routinely collected health data might reduce antibiotic use nationwide without requiring the substantial resources and structural efforts of other antibiotic stewardship programs. Objective: To determine if quarterly antibiotic prescription feedback over 2 years reduces antibiotic use when implemented in a complex health care system. Design, Setting, and Participants: Pragmatic randomized trial using routinely collected claims data on 2900 primary care physicians with the highest antibiotic prescription rates in Switzerland...
December 27, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28025610/evidence-gaps-in-ent-surgery-a-qualitative-survey
#5
REVIEW
Jan Löhler, B Akcicek, F Müller, G Dreier, J J Meerpohl, W Vach, J A Werner
Introduction: As in other disciplines, the burgeoning knowledge in ENT medicine long ago surpassed our ability to adequately absorb it and maintain a proper overview. This can give rise to actual or assumed evidence gaps that can impede the progress of the discipline and evidence-based treatment of patients. Clinics and medical practices also hold to traditional doctrines that shape day-to-day medicine, without these schools being challenged based on evidence. Methods: Between February and June 2015, 160 ENT clinics, including 34 university hospitals, and 2,670 ENT practices took part in a two-arm online survey on existing or perceived evidentiary gaps in ENT medicine using a previously developed questionnaire...
2016: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
https://www.readbyqxmd.com/read/28018764/specialty-preferences-and-the-factors-influencing-them-among-pre-clerkship-medical-students-the-first-study-from-alfaisal-university-college-of-medicine-saudi-arabia
#6
Nouf Alsubaie, Hadeel S Aldhofaian, Lamya Alhuwaimel, Noorah Ruxshan, Fatimah Alghamdi, Ahmad Shamia, Ahmed Abu-Zaid
AIM: To explore the specialty preferences and the factors influencing them among pre-clerkship (second-year and third-year) medical students at Alfaisal University-College of Medicine, Riyadh, Saudi Arabia. METHODS: An online, anonymous, cross-sectional, self-rating survey was administered. The survey explored socio-demographical data, specialty preferences and the factors influencing such preferences. A gender-wise statistical analysis was performed. RESULTS: Two hundred fifty-two students participated in the survey (n=252/308; response rate: 81...
November 23, 2016: Curēus
https://www.readbyqxmd.com/read/28009443/review-myopathology-in-the-times-of-modern-genetics
#7
Markus Schuelke, Nancy Christine Øien, Anders Oldfors
The advent of Next Generation Sequencing (NGS) technologies has accelerated the rate of novel disease gene discovery. Analysis of the large datasets generated by whole exome sequencing, whole genome sequencing, and other NGS approaches poses a challenge to physicians and pathologists searching for disease causing variants amongst the 50,000-3 million polymorphisms typically seen in these datasets. This review describes strategies that successfully combine classical neuropathological investigation (e.g. histology, immunostaining, and electron microscopy) with modern NGS technologies to pinpoint the underlying genetic cause of a disease...
December 23, 2016: Neuropathology and Applied Neurobiology
https://www.readbyqxmd.com/read/28008463/a-dark-side-of-the-cannula-injections-how-arterial-wall-perforations-and-emboli-occur
#8
Tanvaa Tansatit, Prawit Apinuntrum, Thavorn Phetudom
BACKGROUND: Though most injectors prefer to use a cannula rather than a needle, there have been reported cases of blindness following cannula injections. This study investigated possible situations in which a cannula can injure an artery to gain more insight about the vascular complication and its prevention. METHODS: To understand how an arterial injury occurs, five situations favoring vascular injury were simulated and tested. Experiments were performed in 100 arterial segments of 10 soft embalmed cadavers with red latex injections to the arteries...
December 23, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28004975/electronic-kiosks-for-patient-satisfaction-survey-in-radiology
#9
Johannes Boos, Jieming Fang, Aideen Snell, Donna Hallett, Bettina Siewert, Roland L Eisenberg, Olga R Brook
OBJECTIVE: The purpose of this article is to analyze patient satisfaction surveys obtained via electronic kiosks in a tertiary-care academic radiology department to detect potential areas of improvement and to identify ways to improve survey response and completion rates. MATERIALS AND METHODS: All patient satisfaction surveys submitted via electronic kiosks and via online surveys between January 2015 and January 2016 were included in this retrospective study. The surveys consisted of questions regarding the patients' overall experience, cleanliness of the department, and interactions with the receptionist, technologist, nurse, and physician...
December 22, 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28002150/screening-and-treatment-of-latent-tuberculosis-among-patients-receiving-biologic-agents-a-national-and-international-survey-of-rheumatologists
#10
Nhu Quynh Tran, Melinda Garcia-Rosell, Debendra Pattanaik, Syed Hasan Raza, Laura Carbone
OBJECTIVE: We sought to understand the current practice patterns of both US and international members of the American College of Rheumatology (ACR) in this regard. METHODS: A set of questionnaires developed by a focus group of faculties and fellows of the Rheumatology Division of University of Tennessee Health Science Center, Memphis, TN, was sent electronically using an online survey tool to 4433 rheumatologists who are ACR members in the United States and internationally...
January 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/27977431/effectiveness-of-extracorporeal-shock-wave-therapy-without-local-anesthesia-in-patients-with-recalcitrant-plantar-fasciitis-a-meta-analysis-of-randomized-controlled-trials
#11
Jing Lou, Shuai Wang, Shuitao Liu, Gengyan Xing
OBJECTIVE: The objective of this meta-analysis was to investigate the efficacy of extracorporeal shock wave therapy in the treatment of recalcitrant plantar fasciitis without local anesthesia. METHODS: The Cochrane Library, EMBASE, PubMed, and Web of Science databases were searched from inception to September 2015 for randomized controlled trials comparing ESWT without local anesthesia versus placebo for treatment of plantar fasciitis in adults. The primary outcome was the 12-week post-intervention success rate of reducing the visual analog scale score by 60% from baseline at the first step in the morning, reducing the VAS score by 60% from baseline during daily activities, reducing the Roles and Maudsley score, reducing overall heel pain, and reducing pain after applying a force meter...
December 9, 2016: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/27966437/physician-consensus-on-preventability-and-predictability-of-readmissions-based-on-standard-case-scenarios
#12
L S van Galen, T Cooksley, H Merten, M Brabrand, C B Terwee, C H Nickel, C P Subbe, R Kidney, J Soong, L Vaughan, I Weichert, M H H Kramer, P W B Nanayakkara
BACKGROUND: Policy makers struggle with unplanned readmissions as a quality indicator since integrating preventability in such indicators is difficult. Most studies on the preventability of readmissions questioned physicians whether they consider a given readmission to be preventable, from which conclusions on factors predicting preventable readmissions were derived. There is no literature on the interobserver agreement of physician judgement. AIM: To assess the degree of agreement among physicians regarding predictability and preventability of medical readmissions...
December 2016: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/27965191/association-between-physician-online-rating-and-quality-of-care
#13
Kanu Okike, Taylor K Peter-Bibb, Kristal C Xie, Okike N Okike
BACKGROUND: Patients are increasingly using physician review websites to find "a good doctor." However, to our knowledge, no prior study has examined the relationship between online rating and an accepted measure of quality. OBJECTIVE: The purpose of this study was to assess the association between online physician rating and an accepted measure of quality: 30-day risk-adjusted mortality rate following coronary artery bypass graft (CABG) surgery. METHODS: In the US states of California, Massachusetts, New Jersey, New York, and Pennsylvania-which together account for over one-quarter of the US population-risk-adjusted mortality rates are publicly reported for all cardiac surgeons...
December 13, 2016: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/27942787/-full-scale-simulation-in-german-medical-schools-and-anesthesia-residency-programs-status-quo
#14
H Baschnegger, O Meyer, A Zech, B Urban, M Rall, G Breuer, S Prückner
BACKGROUND: Simulation has been increasingly used in medicine. In 2003 German university departments of anesthesiology were provided with a full-scale patient simulator, designated for use with medical students. Meanwhile simulation courses are also offered to physicians and nurses. Currently, the national model curriculum for residency programs in anesthesiology is being revised, possibly to include mandatory simulation training. OBJECTIVES: To assess the status quo of full-scale simulation training for medical school, residency and continuing medical education in German anesthesiology...
December 9, 2016: Der Anaesthesist
https://www.readbyqxmd.com/read/27939226/effectiveness-of-a-prehospital-wireless-12-lead-electrocardiogram-and-cardiac-catheterization-laboratory-activation-for-st-elevation-myocardial-infarction
#15
Alain Tanguay, Eric Brassard, Johann Lebon, François Bégin, Denise Hébert, Jean-Michel Paradis
The aim of the study was to determine the prevalence of false-positive and inappropriate cardiac catheterization laboratory (CCL) activation in patients suspected with ST-elevation myocardial infarction (STEMI) diverted to a percutaneous coronary intervention (PCI) facility after paramedics wireless 12-lead electrocardiogram transmission to an emergency physician at an online medical control center. This retrospective study collected data from medical records of patients with suspected STEMI from 2006 to 2014...
November 16, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27936385/interrater-reliability-in-pediatric-urodynamic-tracings-a-pilot-study
#16
Anne G Dudley, Daniel P Casella, Chelsea J Lauderdale, Shilin Zhao, Heidi Chen, Stacy T Tanaka, John C Thomas, John C Pope, Mark C Adams, John W Brock, Chevis N Shannon, Douglass B Clayton
PURPOSE: Urodynamic studies are crucial to neuropathic bladder management and they often determine surgical intervention. However, current evidence indicates that interpretations show poor agreement across physicians. We sought to determine the interrater reliability of urodynamic interpretation in our practice. We hypothesized that there would be strong correlation among pediatric urologists of similar training in a single academic practice. MATERIALS AND METHODS: We retrospectively identified patients with neuropathic bladder who underwent urodynamics at our institution between 2014 and 2015...
December 6, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27922622/the-natural-course-of-spinal-cord-injury-changes-over-40-years-among-those-with-exceptional-survival
#17
J S Krause, J C Newman, J M R Clark, M Dunn
OBJECTIVES: To identify 40-year longitudinal changes in health, activity, employment, life satisfaction and self-rated adjustment after spinal cord injury. STUDY DESIGN: Longitudinal, mailed self-report. METHODS: Participants were identified from outpatient records of a Midwestern USA university hospital in 1973. Follow-ups were conducted in 1984 and approximate 10-year intervals thereafter. A total of 49 participants completed each of the five assessments...
December 6, 2016: Spinal Cord
https://www.readbyqxmd.com/read/27900417/definition-of-hemodynamic-stability-in-blunt-trauma-patients-a-systematic-review-and-assessment-amongst-dutch-trauma-team-members
#18
S A I Loggers, T W A Koedam, G F Giannakopoulos, E Vandewalle, M Erwteman, W P Zuidema
INTRODUCTION: Trauma is a great contributor to mortality worldwide. One of the challenges in trauma care is early identification and management of bleeding. The circulatory status of blunt trauma patients in the emergency room is evaluated using hemodynamic (HD) parameters. However, there is no consensus on which parameters to use. In this study, we evaluate the used terms and definitions in the literature for HD stability and compare those to the opinion of Dutch trauma team members...
November 30, 2016: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/27900184/symptoms-and-risk-factors-of-depression-during-and-after-the-football-career-of-elite-female-players
#19
Birgit Prinz, Jiří Dvořák, Astrid Junge
BACKGROUND: The mental health of elite athletes has received increasing attention in recent years, but no study has evaluated the career-time prevalence of depression, and very few have analysed risk factors of mental health problems during or after the career. METHODS: 157 (response rate 64.1%) female players who played in the German First League answered an anonymous online survey on details of their football career, stressful and helpful conditions, depression and need of psychotherapeutic support during and after the football career...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27896389/-attitudes-and-experiences-regarding-physician-assisted-suicide-a-survey-among-members-of-the-german-association-for-palliative-medicine
#20
Maximiliane Jansky, Birgit Jaspers, Lukas Radbruch, Friedemann Nauck
BACKGROUND: The need to regulate physician-assisted suicide (PAS) and organizations offering assisted suicide has been controversially debated in Germany. Before the German parliament voted on various drafts in November 2015, the German Association for Palliative Medicine surveyed its members on their attitudes and experiences regarding PAS. METHOD: Items for the survey were derived from the literature and consented in a focus group. LITERATURE SEARCH: 2005-2015 - PubMed: PAS [Title/Abstract] UND survey (all countries), grey literature...
January 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
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