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https://www.readbyqxmd.com/read/27915981/molecular-cellular-and-pharmaceutical-aspects-of-autologous-grafts-for-peri-implant-hard-and-soft-tissue-defects
#1
Jiayu Lu, Yongming Hao, Wei Zhao, Chengqi Lv, Derong Zou
The lack of supporting hard and soft tissues always prevents the rehabilitation with dental implants. Among various hard and soft tissue augmentation procedures, autologous grafts have been considered to be the gold standard. Autologous mesenchymal stem cells (MSCs) from bone marrow, dental tissue and adipose tissue have been described as promising alternatives for bone regeneration in the field of dental implantation. Mucosal cells, gingival fibroblasts and dental progenitor cells (DPS) can enhance peri-implant soft tissue augmentation and regenerate periodontal tissues around dental implants...
December 1, 2016: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/27912929/survival-failure-modes-and-function-of-combined-distal-femur-and-proximal-tibia-reconstruction-following-tumor-resection
#2
F Sevelda, W Waldstein, J Panotopoulos, C Stihsen, A Kaider, P T Funovics, R Windhager
BACKGROUND: Tumor spread to the knee joint or skip metastasis to the adjacent bones of the knee require reconstruction with combined distal femur and proximal tibia replacements. The literature on implant survival and failure modes with this type of reconstruction is sparse. The goals of this study were to determine the implant survival, the different failure modes and the functional outcome of this megaendoprosthetic reconstruction. PATIENTS AND METHODS: Thirty-nine patients with combined distal femur and proximal tibia reconstruction were retrospectively reviewed...
November 23, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27908574/reconstruction-of-a-post-traumatic-maxillary-ridge-using-a-radial-forearm-free-flap-and-immediate-tissue-engineering-bone-morphogenetic-protein-bone-marrow-aspirate-concentrate-and-cortical-cancellous-bone-case-report
#3
James C Melville, Ramzey Tursun, J Marshall Green, Robert E Marx
The purpose of this article is to describe reconstruction of the maxillary alveolar ridge by use of a microvascular free flap combined with an immediate tissue-engineered bone graft. This novel surgical technique involved the use of a radial forearm free flap and immediate allogeneic avascular bone graft augmented with bone morphogenetic protein and bone marrow aspirate concentrate. A poly-d,l-lactic acid mesh was used a containment unit for the bone graft. The patient was successfully treated with a viable radial forearm free flap for soft tissue and regeneration of bone with adequate height and width, which allowed the placement of 3 dental implants with excellent arch coordination...
November 9, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27898357/catastrophic-metallosis-after-tumoral-knee-prosthesis-failure-a-case-report
#4
Luca La Verde, Domenico Fenga, Maria Silvia Spinelli, Francesco Rosario Campo, Michela Florio, Michele Attilio Rosa
INTRODUCTION: Metallosis is a condition characterized by an infiltration of periprosthetic soft tissues and bone by metallic debris resulting from wear or failure of joint arthroplasties. PRESENTATION OF CASE: Authors describe a case of a 45-year-old man treated for an osteosarcoma of the distal femur with a modular prosthesis when he was 18 years old, he developed massive metallosis with skin dyspigmentation after 17 years. His medical\surgical history was remarkable for a left tumoral knee prosthesis implanted 21 years ago...
November 18, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27892717/dental-implants-modified-with-drug-releasing-titania-nanotubes-therapeutic-potential-and-developmental-challenges
#5
Karan Gulati, Sašo Ivanovski
The trans-mucosal nature of dental implants presents a unique therapeutic challenge, requiring not only rapid establishment and subsequent maintenance of osseointegration, but also the formation of resilient soft tissue integration. Key challenges in achieving long-term success are sub-optimal bone integration in compromised bone conditions and impaired trans-mucosal tissue integration in the presence of a persistent oral microbial biofilm. These challenges can be targeted by employing a drug-releasing implant modification such as TiO2 nanotubes (TNTs), engineered on titanium surfaces via electrochemical anodization...
November 28, 2016: Expert Opinion on Drug Delivery
https://www.readbyqxmd.com/read/27876350/a-solution-to-the-vessel-shortage-during-free-vascularized-fibular-grafting-for-reconstructing-infected-bone-defects-of-the-femur-bridging-with-vein-transplantation
#6
Ren Gao-Hong, Li Run-Guang, Jiang Gui-Yong, Chen Chao-Jie, Bao Zhi-Gang
PURPOSE: The present study aimed to evaluate the feasibility and clinical efficacy of bridging vein transplantation to deal with the vessel shortage during free vascularized fibular grafting for reconstructing infected bone defects of the femur. METHODS: Twelve patients (aged 15-58 years) with infected bone defects of the femur (between 6.0 and 18.0cm) were recruited in this study. Vacuum sealing drainage were applied after extensive debridement of the infected bone defects and irrigated with 0...
October 22, 2016: Injury
https://www.readbyqxmd.com/read/27871294/newly-designed-retentive-posts-of-mandibular-reconstruction-plate-in-oral-cancer-patients-based-on-preliminary-fem-study
#7
Ik Jae Kwon, Mi Young Eo, Sung Jae Park, Soung Min Kim, Jong Ho Lee
BACKGROUND: The reconstruction of a large mandibular defect poses a challenging issue in oral cancer ablation surgery. One popular option for mandibular continuity reconstruction after tumor resection involves the use of a reconstruction plate (R-plate), which maintains space and contour without bone harvesting. An R-plate, however, cannot provide final functional loading rehabilitation with implants or dentures. METHODS: We suggest a new method of functional mandibular reconstruction using retentive posts and an upper prosthesis...
November 21, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27864641/an-open-prospective-single-cohort-multicenter-study-evaluating-the-novel-tapered-conical-connection-implants-supporting-single-crowns-in-the-anterior-and-premolar-maxilla-interim-1-year-results
#8
Alexander Fügl, Werner Zechner, Alessandro Pozzi, Guido Heydecke, Christine Mirzakhanian, Nikolaus Behneke, Alexandra Behneke, Russell A Baer, Robert Nölken, Edward Gottesman, Snjezana Colic
OBJECTIVES: The aim of this multicenter prospective clinical study was to evaluate anodized tapered implants with a conical connection and integrated platform shifting placed in the anterior and premolar maxilla. MATERIALS AND METHODS: The study enrolled patients requiring single-tooth restorations in healed sites of maxillary anterior and premolar teeth. All implants were immediately temporized. Clinical and radiographic evaluations were conducted at implant insertion, 6 months, and 1 year...
November 18, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27861672/a-two-year-evaluation-of-a-sloped-marginal-contour-implant-system-placed-in-healed-sites
#9
Philip Km Lee, Adam Sc Siu
PURPOSE: The purpose of this clinical trial was to evaluate the survival rate, bone remodeling, and soft tissue health around sloped marginal contour implants when placed in healed sites posteriorly in the mouth. MATERIALS AND METHODS: Implants were placed in healed sites at premolar and molar regions. After a 3-month osseointegration period, definitive prostheses were connected. Clinical and radiographic examinations were performed at implant placement and then 1, 3, 6, 12, and 24 months after implant placement...
November 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27861669/bone-level-changes-around-delayed-dental-implants-in-previous-large-bone-defects-filled-with-reactive-soft-tissue-after-extraction-a-cone-beam-computed-tomography-study
#10
Roberto Crespi, Paolo Capparé, Giovanni Crespi, Giorgio Gastaldi, Enrico Gherlone
PURPOSE: The objective of this study was to evaluate new bone regeneration around delayed implants positioned in large bone defects, filled with reactive soft tissue, using cone beam computed tomography (CBCT) at a follow-up of 3 years. MATERIALS AND METHODS: Patients presented large bone defects after tooth extraction. Reactive soft tissue was left in the defects, and no grafts were used. CBCT scans were performed before tooth extraction and upon implant placement (at 3 months after extraction), and bone volume measurements were then evaluated 3 years after implant placement...
November 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27861667/esthetic-outcome-of-implants-placed-in-fresh-extraction-sockets-by-clinicians-with-or-without-experience-a-medium-term-retrospective-evaluation
#11
Antonio Barone, Paolo Toti, Simone Marconcini, Giacomo Derchi, Marchionni Saverio, Ugo Covani
PURPOSE: This study discussed a 3-year retrospective survey of clinical and esthetic outcomes of immediate implants placed by experienced senior surgeons and residents in implant dentistry. MATERIALS AND METHODS: The retrospective chart review included patients who received single-tooth extraction and immediate implant placement at the Tuscan Stomatology Institute between 2009 and 2011. Treated independent postextraction areas were divided into two groups according to the operator's experience: expert versus nonexpert group...
November 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27861661/retrospective-cohort-study-of-4-591-straumann-implants-placed-in-2-060-patients-in-private-practice-with-up-to-10-year-follow-up-the-relationship-between-crestal-bone-level-and-soft-tissue-condition
#12
David French, David L Cochran, Ronen Ofec
PURPOSE: The purpose of this report is to describe the crestal bone level (CBL) around implants of various designs, describe the peri-implant soft tissue condition, and evaluate the relationship between the two over time. MATERIALS AND METHODS: This retrospective cohort study reports on 2,060 patients with 4,591 implants evaluated after 3 months; 1, 3, 5, and 7 years; and up to 10 years. Periapical radiographs were used to evaluate changes in CBL. The peri-implant soft tissue was evaluated using a modified Bleeding Index termed the Implant Mucosal Index (IMI) where: 0 = no bleeding; 1 = minimal, single-point bleeding; 2 = moderate, multipoint bleeding; 3 = profuse, multipoint bleeding; and 4 = suppuration...
November 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27861658/a-comparison-of-tapered-and-nontapered-implants-in-the-minipig
#13
David Cochran, Andreas Stavropoulos, Marcel Obrecht, Benjamin Pippenger, Michel Dard
PURPOSE: Tapered implants are thought to result in equivalent long-term stability and marginal peri-implant bone height in comparison to cylindrical implants. The goal of this study was to compare the primary stability and osseointegration of a novel bone-level tapered-wall implant to a control bone-level cylindrical implant with exactly the same surface characteristics, in a direct side-by-side comparison in an animal model. MATERIALS AND METHODS: Mandibular premolars and first molars were extracted in 11 G...
November 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27861657/soft-and-hard-tissue-changes-following-immediate-placement-or-immediate-restoration-of-single-tooth-implants-in-the-esthetic-zone-a-systematic-review-and-meta-analysis
#14
Qi Yan, Li-Qun Xiao, Mei-Ying Su, Yan Mei, Bin Shi
PURPOSE: This systematic review aimed to compare immediate protocols with conventional protocols of single-tooth implants in terms of changes in the surrounding hard and soft tissue in the esthetic area. MATERIALS AND METHODS: Electronic and manual searches were performed in PubMed, EMBASE, Cochrane, and other data systems for research articles published between January 2001 and December 2014. Only randomized controlled trials (RCTs) reporting on hard and or soft tissue characteristics following a single-tooth implant were included...
November 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27861653/sinus-floor-elevation-and-augmentation-using-synthetic-nanocrystalline-and-nanoporous-hydroxyapatite-bone-substitute-materials-preliminary-histologic-results
#15
Sofia-Maria Belouka, Frank Peter Strietzel
PURPOSE: To compare the tissue composition of augmented sites after using two different synthetic bone substitute materials, nanocrystalline and nanoporous hydroxyapatite (HA), for sinus floor elevation and augmentation. MATERIALS AND METHODS: Forty-four patients received 88 titanium screw implants (Camlog Promote plus) of 4.3-mm diameter and 11- or 13-mm length, placed simultaneously during sinus floor elevation and augmentation. Nanocrystalline (Ostim) or nanoporous (NanoBone) HA were used exclusively...
November 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27861650/influence-of-four-different-abutment-materials-and-the-adhesive-joint-of-two-piece-abutments-on-cervical-implant-bone-and-soft-tissue
#16
Christian Mehl, Volker Gaβling, Stephan Schultz-Langerhans, Yahya Açil, Telse Bähr, Jörg Wiltfang, Matthias Kern
PURPOSE: The main aim of this study was to evaluate the influence of four different abutment materials and the adhesive joint of two-piece abutments on the cervical implant bone and soft tissue. MATERIALS AND METHODS: Sixty-four titanium implants (Camlog Conelog; 4.3 ± 9 mm) were placed bone level into the edentulous arches of four minipigs. Four different types of abutments were placed at implant exposure: zirconium dioxide, lithium disilicate, and titanium bonded to a titanium luting base with resin cement; one-piece titanium abutments served as the control...
November 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27833766/peri-implant-bone-loss-and-peri-implantitis-a-report-of-three-cases-and-review-of-the-literature
#17
Vanchit John, Daniel Shin, Allison Marlow, Yusuke Hamada
Dental implant supported restorations have been added substantially to the clinical treatment options presented to patients. However, complications with these treatment options also arise due to improper patient selection and inadequate treatment planning combined with poor follow-up care. The complications related to the presence of inflammation include perimucositis, peri-implant bone loss, and peri-implantitis. Prevalence rates of these complications have been reported to be as high as 56%. Treatment options that have been reported include nonsurgical therapy, the use of locally delivered and systemically delivered antibiotics, and surgical protocols aimed at regenerating the lost bone and soft tissue around the implants...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27833739/surgical-non-regenerative-treatments-for-peri-implantitis-a-systematic-review
#18
REVIEW
Ausra Ramanauskaite, Povilas Daugela, Ricardo Faria de Almeida, Nikola Saulacic
OBJECTIVES: The purposes of the present study were 1) to systematically review the literature on the surgical non-regenerative treatments of peri-implantitis and 2) to determine a predictable therapeutic option for the clinical management of peri-implantitis lesions. MATERIAL AND METHODS: The study search was performed on primary database MEDLINE and EMBASE from 2005 until 2016. Sequential screenings at the title, abstract, and full-text levels were performed. Clinical human studies in the English language that had reported changes in probing depth (PD) and/or bleeding on probing (BOP) and/or radiologic marginal bone level changes after peri-implantitis surgical non-regenerative treatment at 6-month follow-up or longer were included accordingly PRISMA guidelines...
July 2016: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/27833733/diagnostic-principles-of-peri-implantitis-a-systematic-review-and-guidelines-for-peri-implantitis-diagnosis-proposal
#19
REVIEW
Ausra Ramanauskaite, Gintaras Juodzbalys
OBJECTIVES: To review and summarize the literature concerning peri-implantitis diagnostic parameters and to propose guidelines for peri-implantitis diagnosis. MATERIAL AND METHODS: An electronic literature search was conducted of the MEDLINE (Ovid) and EMBASE databases for articles published between 2011 and 2016. Sequential screening at the title/abstract and full-text levels was performed. Systematic reviews/guidelines of consensus conferences proposing classification or suggesting diagnostic parameters for peri-implantitis in the English language were included...
July 2016: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/27833336/sub-periosteal-dissection-with-denture-guided-epithelial-regeneration-a-novel-method-for-peri-implant-soft-tissue-management-in-reconstructed-mandibles
#20
Vinay V Kumar, P C Jacob, Moni A Kuriakose
BACKGROUND: In patients with reconstructed mandibles using free fibula flaps, management of soft tissues around implants supporting dental rehabilitation, is often a clinical problem. AIM: The aim of this paper is to describe a new technique, namely "Sub-periosteal dissection and denture-guided epithelial regeneration (SD-DGER)", as a method of peri-implant soft tissue management in these patients. MATERIALS AND METHODS: The technique consists of performing a subperiosteal dissection with creation of buccal and lingual flaps...
December 2016: Journal of Maxillofacial and Oral Surgery
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