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Cartilage AND ultrasound

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https://www.readbyqxmd.com/read/28439945/enhancement-of-cardiomyogenesis-in-murine-stem-cells-by-low-intensity-ultrasound
#1
Ailing Teo, Amir Morshedi, Jen-Chieh Wang, Yufeng Zhou, Mayasari Lim
OBJECTIVES: Low-intensity ultrasound (LIUS) has been shown to enhance bone and cartilage regeneration from stem cells. The ease of its incorporation makes it an attractive mechanical stimulus for not only osteogenesis and chondrogenesis, but also cardiomyogenesis. However, to date, no study has investigated its effects on cardiomyogenesis from embryonic stem cells. METHODS: In this study, murine embryonic stem cells were differentiated via embryoid body formation and plating, and after 3 days they were subjected to daily 10 minutes of LIUS treatment with various conditions: (1) low-pulsed (21 mW/cm(2) , 20% duty cycle), (2) low-continuous, (3) high-pulsed (147 mW/cm(2) , 20% duty cycle), and (4) high-continuous LIUS...
April 25, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28419479/sonographic-diagnosis-of-a-radiographically-occult-displaced-fracture-of-a-costal-cartilage
#2
Chandra Bortolotto, Egisto Federici, Ferdinando Draghi, Stefano Bianchi
We report the case of a 22-year-old athlete who sustained a blunt thoracic trauma to the right chest causing a costal cartilage fracture. Plain radiographs revealed no abnormalities while sonographic (US) examination performed a week later because of persistent pain led to the diagnosis of a displaced fracture of the right tenth costal cartilage. A follow-up US examination confirmed the healing of the fracture and allowed the patient to return to competitive sport activity. We recommend the use of US in patients with persisting pain after thoracic trauma with negative plain radiographs of the ribs to rule out radiographically occult costal cartilage fractures...
April 17, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28355674/ultrasound-of-the-knee-common-pathology-excluding-extensor-mechanism
#3
Jon A Jacobson, Thumanoon Ruangchaijatuporn, Viviane Khoury, Olaf Magerkurth
Ultrasound can be used to diagnose many types of pathology and guide various diagnostic or therapeutic procedures. The most common applications for musculoskeletal ultrasound of the knee include evaluation of the joint recesses, the extensor mechanism, and bursae including Baker's cyst. However, a role exists for ultrasound in the evaluation of cartilage, other tendons, ligaments, peripheral nerves, osseous structures, and vasculature. This article reviews common pathologies of these structures as seen with ultrasound...
April 2017: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/28341489/automatic-evaluation-of-scan-adequacy-and-dysplasia-metrics-in-2-d-ultrasound-images-of-the-neonatal-hip
#4
Niamul Quader, Antony J Hodgson, Kishore Mulpuri, Emily Schaeffer, Rafeef Abugharbieh
Ultrasound (US) imaging of an infant's hip joint is widely used for early detection of developmental dysplasia of the hip. In current US-based diagnosis of developmental dysplasia of the hip, trained clinicians acquire US images and, if they judge them to be adequate (i.e., to contain relevant hip joint structures), analyze them manually to extract clinically useful dysplasia metrics. However, both the scan adequacy classification and dysplasia metrics extraction steps exhibit significant variability within and between both clinicians and institutions, which can result in significant over- and undertreatment rates...
March 21, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28295049/structure-symptom-relationship-with-wide-area-ultrasound-scanning-of-knee-osteoarthritis
#5
Jana Podlipská, Juhani M Koski, Päivi Kaukinen, Marianne Haapea, Osmo Tervonen, Jari P Arokoski, Simo Saarakkala
The aetiology of knee pain in osteoarthritis (OA) is heterogeneous and its relationship with structural changes and function is unclear. Our goal was to determine the prevalence of wide-area scanned ultrasound-defined knee OA structural features and their association with pain and functional impairment in 79 symptomatic and 63 asymptomatic subjects. All subjects underwent ultrasound knee wide-area scanning and the severity of articular cartilage degeneration, the presence and size of osteophytes, and meniscal extrusion were evaluated...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28250136/definition-and-reliability-assessment-of-elementary-ultrasonographic-findings-in-calcium-pyrophosphate-deposition-disease-a-study-by-the-omeract-calcium-pyrophosphate-deposition-disease-ultrasound-subtask-force
#6
Georgios Filippou, Carlo A Scirè, Nemanja Damjanov, Antonella Adinolfi, Greta Carrara, Valentina Picerno, Carmela Toscano, George A Bruyn, Maria Antonietta D'Agostino, Andrea Delle Sedie, Emilio Filippucci, Marwin Gutierrez, Mihaela Micu, Ingrid Möller, Esperanza Naredo, Carlos Pineda, Francesco Porta, Wolfgang A Schmidt, Lene Terslev, Violeta Vlad, Pascal Zufferey, Annamaria Iagnocco
OBJECTIVE: To define the ultrasonographic characteristics of calcium pyrophosphate crystal (CPP) deposits in joints and periarticular tissues and to evaluate the intra- and interobserver reliability of expert ultrasonographers in the assessment of CPP deposition disease (CPPD) according to the new definitions. METHODS: After a systematic literature review, a Delphi survey was circulated among a group of expert ultrasonographers, who were members of the CPPD Ultrasound (US) Outcome Measures in Rheumatology (OMERACT) subtask force, to obtain definitions of the US characteristics of CPPD at the level of fibrocartilage (FC), hyaline cartilage (HC), tendon, and synovial fluid (SF)...
March 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28249616/tumor-to-tumor-metastases-papillary-thyroid-carcinoma-into-a-clear-cell-renal-cell-carcinoma
#7
Jin Soo Andy Song, S Mark Taylor, Jonathan Trites, Matthew H Rigby, Martin Joseph Bullock, Jennifer Merrimen, Ricardo Rendon, Robert D Hart
BACKGROUND: Thyroid metastases to distant sites are uncommon incidents, most often metastasizing to the lungs and bones. Rates of metastasis to the kidney are particularly low, ranging from 2.8-3.8% for papillary and 6-20% for follicular variants of well-differentiated thyroid cancers (WDTCs). In rare instances, tumor-to-tumor metastasis between two true primary neoplasms can occurs. This medical phenomenon has previously occurred as a clear cell renal cell carcinoma (CCRCC) spreading to a WDTC...
March 1, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28226218/assessing-cartilage-biomechanical-properties-techniques-for-evaluating-the-functional-performance-of-cartilage-in-health-and-disease
#8
Benjamin A Lakin, Brian D Snyder, Mark W Grinstaff
Osteoarthritis (OA) affects millions of people and results in weakened hyaline cartilage due to overloading. During joint articulation, hyaline cartilage must withstand high loads while maintaining low friction to prevent wear and tissue loss. Thus, cartilage compressive stiffness and the coefficient of friction are important indicators of the tissue's functional performance. These mechanical properties are often measured ex vivo using mechanical testing regimens, but arthroscopic handheld probes (e.g., for indentation testing, ultrasound, and optical coherence tomography) and noninvasive imaging modalities (e...
February 2, 2017: Annual Review of Biomedical Engineering
https://www.readbyqxmd.com/read/28210824/ultrasound-palpation-for-fast-in-situ-quantification-of-articular-cartilage-stiffness-thickness-and-relaxation-capacity
#9
M Schöne, R M Schulz, H Tzschätzsch, P Varga, K Raum
Most current cartilage testing devices require the preparation of excised samples and therefore do not allow intra-operative application for diagnostic purposes. The gold standard during open or arthroscopic surgery is still the subjective perception of manual palpation. This work presents a new diagnostic method of ultrasound palpation (USP) to acquire applied stress and strain data during manual palpation of articular cartilage. With the proposed method, we obtain cartilage thickness and stiffness. Moreover, repeated palpations allow the quantification of relaxation effects...
February 16, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28182095/early-detection-of-tibial-cartilage-degradation-and-cancellous-bone-loss-in-an-ovariectomized-rat-model
#10
Yinong Wang, Zhiwei Liu, Qing Wang, Qianjin Feng, Wufan Chen
This study aimed to investigate degradation of the articular cartilage and loss of the cancellous bone in an ovariectomized (OVX) rat model simulating early human menopausal stage. Fourteen health female Sprague-Dawley rats were randomly divided into two groups (n = 7 per group): an OVX group that underwent bilateral ovariectomy to create an OVX model with low estrogen levels and a sham group in which only the periovarian fatty tissue was exteriorized. All the animals were sacrificed at 3 weeks after ovariectomy...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28147365/measurement-of-fibrosis-in-crohn-s-disease-strictures-with-imaging-and-blood-biomarkers-to-inform-clinical-decisions
#11
REVIEW
Peter D R Higgins
BACKGROUND: Distinguishing fibrosis from inflammation in an intestinal stricture in Crohn's disease is quite difficult. The absence of signs of inflammation on CT or MRI does not prove the absence of inflammation, as most strictures have a mix of fibrosis and inflammation. Identifying refractory fibrosis and distinguishing the patients who will respond to anti-inflammatory therapy from those who will require surgery are important clinical requirements, and several new technologies in imaging and serum biomarkers are being applied to this problem...
2017: Digestive Diseases
https://www.readbyqxmd.com/read/28137441/effects-of-habitual-knuckle-cracking-on-metacarpal-cartilage-thickness-and-grip-strength
#12
M T Yildizgören, T Ekiz, S Nizamogullari, A D Turhanoglu, H Guler, N Ustun, M Kara, L Özçakar
Joint cracking involves a manipulation of the finger joints resulting in an audible crack. This study aimed to determine whether habitual knuckle cracking (KC) leads to an alteration in grip strength and metacarpal head (MH) cartilage thickness. Thirty-five habitual knuckle crackers (cracking their joints ≥5times/day) (20 M, 15 F, aged 19-27 years) and 35 age-, gender-, and body mass index-matched non-crackers were enrolled in the study. MH cartilage thickness was measured with ultrasound and grip strength was measured with an analog Jamar hand dynamometer...
February 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28137404/relevant-aspects-of-imaging-in-the-diagnosis-and-management-of-gout
#13
Eloy De Avila Fernandes, Samuel Brighenti Bergamaschi, Tatiane Cantarelli Rodrigues, Gustavo Coelho Dias, Ralff Malmann, Germano Martins Ramos, Soraya Silveira Monteiro
Gout is an inflammatory arthritis characterized by the deposition of monosodium urate crystals in the synovial membrane, articular cartilage and periarticular tissues leading to inflammation. Men are more commonly affected, mainly after the 5th decade of life. Its incidence has been growing with the population aging. In the majority of the cases, the diagnosis is made by clinical criteria and synovial fluid analysis, in search for monosodium urate crystals. Nonetheless, gout may sometimes have atypical presentations, complicating the diagnosis...
January 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28093371/sonographically-guided-knee-meniscus-injections-feasibility-techniques-and-validation
#14
Michael R Baria, Jacob L Sellon, Dan Lueders, Jay Smith
BACKGROUND: There is a growing interest in the use of biologic agents such as platelet-rich plasma and mesenchymal stem/stromal cells to treat musculoskeletal injuries, including meniscal tears. Although previous research has documented the role of diagnostic ultrasound to evaluate meniscal tears, sonographically guided (SG) techniques to specifically deliver therapeutic agents into the meniscus have not been described. OBJECTIVE: To describe and validate SG injection techniques for the body and posterior horn of the medial and lateral meniscus...
January 16, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28078503/efficacy-of-pulsed-nd-yag-laser-in-the-treatment-of-patients-with-knee-osteoarthritis-a-randomized-controlled-trial
#15
Mohamed Salaheldien Mohamed Alayat, Tarek Helmy Ahmed Aly, Aly Elsayed Mohamed Elsayed, Ammar Suliman Mohamed Fadil
The purpose of this study was to investigate the effects of pulsed Nd:YAG laser plus glucosamine/chondroitin sulfate (GCS) in patients with knee osteoarthritis (KOA) by examining changes in pain and knee function, as well as synovial thickness (ST) and femoral cartilage thickness (FCT). Sixty-seven male patients participated, with a mean (SD) age of 53.85 (4.39) years, weight of 84.01 (4.70) kg, height of 171.51 (3.96) cm, and BMI of 28.56 (1.22). Group 1 was treated with high-intensity laser therapy (HILT), GCS, and exercises (HILT + GCS + EX)...
April 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28072483/optimization-of-ultrasound-transducer-positioning-for-endotracheal-tube-placement-confirmation-in-cadaveric-model
#16
Tiffany Lonchena, Sokpoleak So, James Ibinson, Peter Roolf, Steven L Orebaugh
OBJECTIVES: Sonography has been suggested as a possible means of endotracheal tube (ETT) placement confirmation. However, optimum ultrasound transducer placement has not been established. Using a cadaveric model, ETT placement by the sonographic appearance at the thyroid cartilage, cricoid cartilage, and suprasternal notch in the upper airway was assessed to determine which ultrasound transducer placement offered the most optimal images for ETT confirmation in the airway. METHODS: One provider intubated 5 cadavers, with the ultrasound transducer at each of the 3 levels, for a total of 30 intubations per specimen, while 2 providers assigned a visual score of 1 (subtle), 2 (clear), or 3 (pronounced) to each sonogram of the ETT in the airway...
February 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28072470/sonographic-dynamic-description-of-the-laryngeal-tract-definition-of-quantitative-measures-to-characterize-vocal-fold-motion-and-estimation-of-their-normal-values
#17
Héloïse Bergeret-Cassagne, Diane S Lazard, Muriel Lefort, Siham Hachi, Laurence Leenhardt, Fabrice Menegaux, Gilles Russ, Christophe Trésallet, Frédérique Frouin
Vocal fold motion was analyzed during free breathing using two-dimensional dynamic ultrasound imaging. Two cadavers were first analyzed to define easily identifiable landmarks. Motion of the laryngeal tract was then analyzed in an axial plane. Left and right arytenoids and thyroid cartilage were defined on images corresponding to abduction and adduction of the laryngeal tract. Associated area measurements were established for 50 healthy subjects. All area indices were significantly larger during abduction than adduction...
May 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27981278/knee-ultrasound-from-research-to-real-practice-a-systematic-literature-review-of-adult-knee-ultrasound-assessment-feasibility-studies
#18
Alexandra Peltea, Florian Berghea, Tania Gudu, Ruxandra Ionescu
OBJECTIVE: To identify and analyse existing data regarding knee ultrasound (US) feasibility in clinical practice. Material and methods: A systematic literature review was performed using the terms: ("knee") AND ("ultrasound" OR "ultrasonography") AND ("feasibility" OR "pilot" OR "proof of concept"). Feasibility studies regarding knee US or US aided maneuver involving knee joint, published during 2005-2015, were selected and evaluated against a complex framework constructed around mandatory key areas for feasibility studies: acceptability, demand, implementation, practicality, adaptation, integration and expansion...
December 5, 2016: Medical Ultrasonography
https://www.readbyqxmd.com/read/27975090/near-infrared-spectroscopic-assessment-of-developing-engineered-tissues-correlations-with-compositional-and-mechanical-properties
#19
Arash Hanifi, Uday Palukuru, Cushla McGoverin, Michael Shockley, Eliot Frank, Alan Grodzinsky, Richard G Spencer, Nancy Pleshko
Articular cartilage degeneration causes pain and reduces the mobility of millions of people annually. Regeneration of cartilage is challenging, due in part to its avascular nature, and thus tissue engineering approaches for cartilage repair have been studied extensively. Current techniques to assess the composition and integrity of engineered tissues, including histology, biochemical evaluation, and mechanical testing, are destructive, which limits real-time monitoring of engineered cartilage tissue development in vitro and in vivo...
April 10, 2017: Analyst
https://www.readbyqxmd.com/read/27965140/multimodality-scoring-of-chondral-injuries-in-the-equine-fetlock-joint-ex%C3%A2-vivo
#20
J K Sarin, H Brommer, D Argüelles, P H Puhakka, S I Inkinen, I O Afara, S Saarakkala, J Töyräs
OBJECTIVE: We investigate the potential of a prototype multimodality arthroscope, combining ultrasound, optical coherence tomography (OCT) and arthroscopic indentation device, for assessing cartilage lesions, and compare the reliability of this approach with conventional arthroscopic scoring ex vivo. DESIGN: Areas of interest (AIs, N = 43) were selected from equine fetlock joints (N = 5). Blind-coded AIs were independently scored by two equine surgeons employing International Cartilage Repair Society (ICRS) scoring system via conventional arthroscope and multimodality arthroscope, in which high-frequency ultrasound and OCT catheters were attached to an arthroscopic indentation device...
May 2017: Osteoarthritis and Cartilage
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