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https://www.readbyqxmd.com/read/28595685/implementing-psychopharmacology-rounds-in-a-nursing-facility-to-improve-antipsychotic-usage
#1
Evan Sasson, Marian James, Berhane Wubshet, Darko Todorov, Henry Cohen
OBJECTIVES: Evaluate whether implementing of pharmacy-led psychopharmacology rounds in a nursing facility will improve the rate of antipsychotic use. DESIGN: Single-center, prospective; medication use evaluation (MUE). SETTING: Rutland Nursing Home, Brooklyn, New York. PARTICIPANTS: Nursing facility residents, excluding the pediatric unit. INTERVENTIONS: Weekly interdisciplinary psychopharmacology rounds that include: clinical pharmacists, nurse managers, medical director, social workers, and administration...
June 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/28560664/external-validation-of-the-diffuse-intrinsic-pontine-glioma-survival-prediction-model-a-collaborative-report-from-the-international-dipg-registry-and-the-siope-dipg-registry
#2
Sophie E M Veldhuijzen van Zanten, Adam Lane, Martijn W Heymans, Joshua Baugh, Brooklyn Chaney, Lindsey M Hoffman, Renee Doughman, Marc H A Jansen, Esther Sanchez, William P Vandertop, Gertjan J L Kaspers, Dannis G van Vuurden, Maryam Fouladi, Blaise V Jones, James Leach
We aimed to perform external validation of the recently developed survival prediction model for diffuse intrinsic pontine glioma (DIPG), and discuss its utility. The DIPG survival prediction model was developed in a cohort of patients from the Netherlands, United Kingdom and Germany, registered in the SIOPE DIPG Registry, and includes age <3 years, longer symptom duration and receipt of chemotherapy as favorable predictors, and presence of ring-enhancement on MRI as unfavorable predictor. Model performance was evaluated by analyzing the discrimination and calibration abilities...
May 30, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28556494/familial-association-of-abstinent-remission-from-alcohol-use-disorder-in-first-degree-relatives-of-alcohol-dependent-treatment-seeking-probands
#3
Vivia V McCutcheon, Marc A Schuckit, John R Kramer, Grace Chan, Howard J Edenberg, Tom L Smith, Annah K Bender, Victor Hesselbrock, Michie Hesselbrock, Kathleen K Bucholz
BACKGROUND AND AIMS: Studies that have included family history of alcohol use disorder (AUD) as a predictor of remission from AUD have yielded few significant results. The goals of this study were to estimate the association of persistent AUD, non-abstinent remission and abstinent remission ("AUD/remission status") in a proband with AUD/remission status in a relative and to test whether this association differed in related and unrelated proband-relative pairs. DESIGN: High-risk family study of alcohol dependence...
May 27, 2017: Addiction
https://www.readbyqxmd.com/read/28549048/disposable-versus-reusable-absorbent-underpads-for-prevention-of-hospital-acquired-incontinence-associated-dermatitis-and-pressure-injuries
#4
Kathleen Francis, Sau Man Pang, Brenda Cohen, Helene Salter, Peter Homel
PURPOSE: The primary purpose of our study was to determine if there is a difference in the occurrence of hospital-acquired pressure injuries (HAPIs) and incontinence-associated dermatitis (IAD) in incontinent adults using a disposable versus reusable absorptive underpads. We also compared hospital length of stay in the 2 groups. DESIGN: Randomized controlled trial using cluster randomization based on inpatient care unit. SUBJECTS AND SETTING: Four hundred sixty-two patients admitted to 4 medical-surgical study units participated in the study; 252 used reusable underpads (control group) and 210 subjects used disposable underpads (intervention group)...
May 25, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28469901/use-of-electronic-clinical-decision-support-and-hard-stops-to-decrease-unnecessary-thyroid-function-testing
#5
Sonia Dalal, Siddharth Bhesania, Steven Silber, Parag Mehta
NewYork-Presbyterian Brooklyn Methodist Hospital embarked on a Zero Unnecessary Study (ZEUS) initiative, whereby all aspects of clinical care were evaluated and strategies were implemented to mitigate waste. An opportunity was found in regards to thyroid function testing. It has been shown that certain TFTs are ordered far more often than clinically indicated. Free T3 (fT3) and Free T4 (fT4) are only indicated when the TSH is abnormal in the inpatient setting, with rare exceptions. Thus, a clinical algorithm for Clinical Decision Support (CDS) and Hard Stops (HS) were incorporated into the Electronic Medical Record (EMR) to prevent fT3 or fT4 to be ordered without an abnormal TSH, with certain predefined exceptions...
2017: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/28459090/%C3%A2-parcel-feature-data-derived-from-google-street-view-images-for-urban-land-use-classification-in-brooklyn-new-york-cityfor-urban-land-use-classification-in-brooklyn-new-york-cityretain
#6
Weixing Zhang, Weidong Li, Chuanrong Zhang, Dean M Hanink, Xiaojiang Li, Wenjie Wang
Google Street View (GSV) was used for urban land use classification, together with airborne light detection and ranging (LiDAR) data and high resolution orthoimagery, by a parcel-based method. In this data article, we present the input raw GSV images, intermediate products of GSV images, and final urban land use classification data that are related to our research article "Parcel-based urban land use classification in megacity using airborne LiDAR, high resolution orthoimagery, and Google Street View" (Zhang et al...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28416155/tracking-of-muscular-strength-and-power-from-youth-to-young-adulthood-longitudinal-findings-from-the-childhood-determinants-of-adult-health-study
#7
Brooklyn J Fraser, Michael D Schmidt, Quan L Huynh, Terence Dwyer, Alison J Venn, Costan G Magnussen
OBJECTIVES: Low muscular fitness levels have previously been reported as an independent risk factor for chronic disease outcomes. Muscular fitness tracking, the ability to maintain levels measured at one point in time to another point in time, was assessed from youth to adulthood to provide insight into whether early identification of low muscular fitness in youth is possible. DESIGN: Prospective longitudinal study. METHODS: Study including 623 participants who had muscular fitness measures in 1985 (aged 9, 12 or 15 years) and again 20 years later in young adulthood...
March 31, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28379862/vermont-hub-and-spoke-model-of-care-for-opioid-use-disorder-development-implementation-and-impact
#8
John R Brooklyn, Stacey C Sigmon
BACKGROUND: Opioid use disorders (OUDs) are reaching epidemic proportions in the United States, and many geographic areas struggle with a persistent shortage in availability of opioid agonist treatment. Over the past 5 years, Vermont addiction medicine physicians and public health leaders have responded to these challenges by developing an integrated hub-and-spoke opioid treatment network. METHODS: In the present report, we review the development, implementation, and impact of this novel hub-and-spoke model for expanding OUD treatment in Vermont...
April 4, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28348089/the-development-of-cardiac-arrhythmia-ablation-a-conversation-with-melvin-a-scheinman-md
#9
Melvin A Scheinman, John D. Rutherford
Dr Melvin A. Scheinman is Professor of Medicine and holds the Walter H. Shorenstein Endowed Chair in Cardiology at the University of California, San Francisco. He has received awards including the Paul Dudley White Award for Excellence in Teaching by the American Heart Association and the Distinguished Science Award of the American College of Cardiology. He grew up in Brooklyn, New York, and took his undergraduate degree at Johns Hopkins University, where he graduated first in his class. Postgraduate medical education included the Albert Einstein College of Medicine, residency training at the University of North Carolina (Chapel Hill), and cardiology training at the University of California, San Francisco Medical Center...
March 28, 2017: Circulation
https://www.readbyqxmd.com/read/28344823/forty-nine-years-in-biomaterials-science-an-interview-with-buddy-ratner
#10
Buddy Ratner
Buddy Ratner talks to Francesca Lake, Managing Editor. After receiving his PhD in polymer chemistry from the Polytechnic Institute of Brooklyn (USA) in 1972, Ratner moved to the University of Washington (USA), where he has since become joint professor of bioengineering and chemical engineering and Michael L & Myrna Darland Endowed Chair in Technology Commercialization. Since 1996, he has led the UWEB Research Center for Biomaterials at the University of Washington, originally funded by the National Science Foundation...
March 2017: Future Science OA
https://www.readbyqxmd.com/read/28319395/spreading-kinetics-of-ultrathin-liquid-films-using-molecular-dynamics
#11
Brooklyn A Noble, C Mathew Mate, Bart Raeymaekers
Ultrathin liquid films play a critical role in numerous engineering applications. Although crucial to the design and application of ultrathin liquid films, the physical mechanisms that govern spreading on the molecular scale are not well-understood, and disagreement among experiments, simulations, and theory remains. We use molecular dynamics simulations to quantify the speed at which the edge of a polymer droplet advances on a flat substrate as a function of various environmental and design parameters. We explain the physical mechanisms that drive and inhibit spreading, identify different spreading regimes, and clarify transitions between spreading regimes...
March 27, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28259216/the-relationship-of-baseline-prostate-specific-antigen-and-risk-of-future-prostate-cancer-and-its-variance-by-race
#12
Daniel P Verges, Hasan Dani, William A Sterling, Jeremy Weedon, William Atallah, Komal Mehta, David Schreiber, Jeffrey P Weiss, Nicholas T Karanikolas
PURPOSE: Several studies suggest that a baseline prostate specific antigen (PSA) measured in young men predicts future risk of prostate cancer. Considering recent recommendations against PSA screening, high-risk populations (e.g. black men, men with a high baseline PSA) may be particularly vulnerable in the coming years. Thus, we investigated the relationship between baseline PSA and future prostate cancer in a black majority-minority urban population. MATERIALS AND METHODS: A retrospective analysis was performed of the prostate biopsy database (n = 994) at the Brooklyn Veterans Affairs Hospital...
April 2017: Journal of the National Medical Association
https://www.readbyqxmd.com/read/28214469/cost-benefit-analysis-of-chlamydia-trachomatis-screening-in-pregnant-women-in-a-high-burden-setting-in-the-united-states
#13
Jared Ditkowsky, Khushal H Shah, Margaret R Hammerschlag, Stephan Kohlhoff, Tamar A Smith-Norowitz
BACKGROUND: Chlamydia trachomatis is the most common bacterial sexually transmitted infection (STI) in the United States (U.S.) [1] and remains a major public health problem. We determined the cost- benefit of screening all pregnant women aged 15-24 for Chlamydia trachomatis infection compared with no screening. METHODS: We developed a decision analysis model to estimate costs and health-related effects of screening pregnant women for C. trachomatis in a high burden setting (Brooklyn, NY)...
February 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28195922/-laughing-gas-given-by-brooklyn-s-celebrated-and-celebrating-dr-g-e-travis
#14
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Anesthesiology
https://www.readbyqxmd.com/read/28110411/development-of-the-siope-dipg-network-registry-and-imaging-repository-a-collaborative-effort-to-optimize-research-into-a-rare-and-lethal-disease
#15
Sophie E M Veldhuijzen van Zanten, Joshua Baugh, Brooklyn Chaney, Dennis De Jongh, Esther Sanchez Aliaga, Frederik Barkhof, Johan Noltes, Ruben De Wolf, Jet Van Dijk, Antonio Cannarozzo, Carin M Damen-Korbijn, Jan A Lieverst, Niclas Colditz, Marion Hoffmann, Monika Warmuth-Metz, Brigitte Bison, David T W Jones, Dominik Sturm, Gerrit H Gielen, Chris Jones, Esther Hulleman, Raphael Calmon, David Castel, Pascale Varlet, Géraldine Giraud, Irene Slavc, Stefaan Van Gool, Sandra Jacobs, Filip Jadrijevic-Cvrlje, David Sumerauer, Karsten Nysom, Virve Pentikainen, Sanna-Maria Kivivuori, Pierre Leblond, Natasha Entz-Werle, Andre O von Bueren, Antonis Kattamis, Darren R Hargrave, Péter Hauser, Miklos Garami, Halldora K Thorarinsdottir, Jane Pears, Lorenza Gandola, Giedre Rutkauskiene, Geert O Janssens, Ingrid K Torsvik, Marta Perek-Polnik, Maria J Gil-da-Costa, Olga Zheludkova, Liudmila Shats, Ladislav Deak, Lidija Kitanovski, Ofelia Cruz, Andres Morales La Madrid, Stefan Holm, Nicolas Gerber, Rejin Kebudi, Richard Grundy, Enrique Lopez-Aguilar, Marta Zapata-Tarres, John Emmerik, Tim Hayden, Simon Bailey, Veronica Biassoni, Maura Massimino, Jacques Grill, William P Vandertop, Gertjan J L Kaspers, Maryam Fouladi, Christof M Kramm, Dannis G van Vuurden
Diffuse intrinsic pontine glioma (DIPG) is a rare and deadly childhood malignancy. After 40 years of mostly single-center, often non-randomized trials with variable patient inclusions, there has been no improvement in survival. It is therefore time for international collaboration in DIPG research, to provide new hope for children, parents and medical professionals fighting DIPG. In a first step towards collaboration, in 2011, a network of biologists and clinicians working in the field of DIPG was established within the European Society for Paediatric Oncology (SIOPE) Brain Tumour Group: the SIOPE DIPG Network...
April 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28093680/the-international-diffuse-intrinsic-pontine-glioma-registry-an-infrastructure-to-accelerate-collaborative-research-for-an-orphan-disease
#16
Joshua Baugh, Ute Bartels, James Leach, Blaise Jones, Brooklyn Chaney, Katherine E Warren, Jenavieve Kirkendall, Renee Doughman, Cynthia Hawkins, Lili Miles, Christine Fuller, Tim Hassall, Eric Bouffet, Adam Lane, Darren Hargrave, Jacques Grill, Lindsey M Hoffman, Chris Jones, Alex Towbin, Sharon A Savage, Michelle Monje, Xiao-Nan Li, David S Ziegler, Sophie Veldhuijzen van Zanten, Christof M Kramm, Dannis G van Vuurden, Maryam Fouladi
Diffuse intrinsic pontine glioma (DIPG), a rare, often fatal childhood brain tumor, remains a major therapeutic challenge. In 2012, investigators, funded by the DIPG Collaborative (a philanthropic partnership among 29 private foundations), launched the International DIPG Registry (IDIPGR) to advance understanding of DIPG. Comprised of comprehensive deidentified but linked clinical, imaging, histopathological, and genomic repositories, the IDIPGR uses standardized case report forms for uniform data collection; serial imaging and histopathology are centrally reviewed by IDIPGR neuro-radiologists and neuro-pathologists, respectively...
January 16, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28007109/trypan-blue-as-a-surgical-adjunct-in-pediatric-cataract-surgery
#17
Gabrielle Fridman, Allison E Rizzuti, Jewel Liao, Mark Rolain, James A Deutsch, Stephen C Kaufman
PURPOSE: To study the effect of trypan blue on lens capsule elasticity and ease of completing a continuous curvilinear capsulorhexis (CCC) in a sheep lens model and to subsequently observe the effects of trypan blue in the surgical setting of 3 pediatric patients. SETTING: State University of New York, Downstate Medical Center, Brooklyn, New York, USA. DESIGN: Prospective case series. METHODS: Twenty-four lenses were excised from fresh sheep globes...
December 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28006894/evaluation-of-clinical-outcome-in-children-and-adolescents-receiving-vancomycin-for-invasive-infections-due-to-methicillin-resistant-staphylococcus-aureus-impact-of-increasing-vancomycin-mics
#18
Aparna Arun, Siddharth Swamy, Kathleen Jacob, Roopali Sharma, Stephan A Kohlhoff, Margaret R Hammerschlag
BACKGROUND: Vancomycin is the preferred drug for the treatment of MRSA infections in children. In adults, treatment failure with vancomycin has been associated with an area under the curve/24 hrs /MIC (AUC24/MIC) ratio of < 400 and high minimum inhibitory concentrations (MIC > 1.0 mg/L). Vancomycin dosing information to ensure optimal AUC24/MIC in the pediatric population remains limited. METHODS: A retrospective chart review from August 2008 to 2011 and a prospective study from September 2011 to October 2013 was conducted on all pediatric patients at two hospitals in Brooklyn, NY with positive cultures for MRSA who received vancomycin...
December 22, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/28002704/interim-buprenorphine-vs-waiting-list-for-opioid-dependence
#19
RANDOMIZED CONTROLLED TRIAL
Stacey C Sigmon, Taylor A Ochalek, Andrew C Meyer, Bryce Hruska, Sarah H Heil, Gary J Badger, Gail Rose, John R Brooklyn, Robert P Schwartz, Brent A Moore, Stephen T Higgins
To the Editor: Opioid-use disorder has reached epidemic proportions, with high attendant costs in terms of increases in overdoses and infectious diseases and in economic costs. Despite the demonstrated efficacy of maintaining abstinence by treating patients with opioid agonists, patients can remain..
December 22, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/28002149/the-effect-of-allopurinol-on-renal-function
#20
Aneesa Krishnamurthy, Deana Lazaro, Dimitre G Stefanov, David Blumenthal, Donald Gerber, Sheetal Patel
BACKGROUND: Hyperuricemia is associated with development of gout, hypertension, and renal disease. The impact of allopurinol, a urate-lowering therapy, on renal function is unclear, especially in patients with chronic kidney disease who are at higher risk of hypersensitivity reaction. OBJECTIVES: The aim of this study was to determine the effect of allopurinol on kidney function in hyperuricemic male veterans. METHODS: This is a retrospective cohort study using pharmacy, medical, and laboratory records of veterans enrolled at the Veterans Administration New York Harbor Healthcare System, Brooklyn campus...
January 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
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