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Thyroid Ultrasound

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https://www.readbyqxmd.com/read/29665748/low-or-undetectable-basal-thyroglobulin-levels-obviate-the-need-for-neck-ultrasound-in-differentiated-thyroid-cancer-patients-after-total-thyroidectomy-and-i-131-ablation
#1
Frederik Verburg, Uwe Maeder, Luca Giovanella, Markus Luster, Christoph Reiners
BACKGROUND: Neck ultrasound (NUS) is currently seen as a main component of follow-up of differentiated thyroid cancer (DTC) and is usually performed regardless of non-stimulated thyroglobulin (Tg) levels. The aim of this study is to determine whether there is a clinical benefit from such a routine NUS in DTC patients. METHODS: We performed a retrospective database study of 3176 cervical ultrasound exams performed in 773 patients between June 15, 1996 and July 1, 2012...
April 18, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29664659/acute-suppurative-thyroiditis-with-thyroid-abscess-and-bilateral-pneumonia-a-case-report
#2
Aleksandar Karanikolic, Miodrag Djordjevic, Nebojsa Djordjevic, Ivan Pesic, Lidija Djordjevic, Aleksandar Zlatic, Toplica Bojic, Vesna Karanikolic
Acute suppurative thyroiditis (AST) leading to thyroid abscess is a rare clinical entity. The aim of this article is to demonstrate a case of severe bilateral pneumonia which originated from a thyroid abscess. The authors report the case of a 57-year-old woman with severe bilateral pneumonia of thyroid origin. The patient had a painful throat and dysphagia for 2 or 3 days. She also had a history of mild fever and hard breathing with a discreet cough 7 days prior to hospital admission. In the past few months, the patient had frequent pneumonias...
February 1, 2018: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29664512/short-stature-and-hypothyroidism-in-a-child-with-nail-patella-syndrome-a-case-report
#3
C Goecke, C Mellado, C García, H García
BACKGROUND: Nail-Patella syndrome (NPS) (OMIM: 161200) or hereditary onycho-osteodysplasia is an autosomal dominant disorder characterized by skeletal anomalies, nail dysplasia, renal and ocular abnor malities. The diagnosis is based on clinical and radiological findings and confirmed by the identification of a heterozygous pathogenic variant in the LMX1B gene. Management of these patients involves conti nuous follow-up and treatment ofthe orthopedical, ocular and renal problems that mayoccur...
February 2018: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/29663106/prevalence-of-thyroid-diseases-in-familial-adenomatous-polyposis-a-systematic-review-and-meta-analysis
#4
Jirat Chenbhanich, Amporn Atsawarungruangkit, Sira Korpaisarn, Tanit Phupitakphol, Soravis Osataphan, Prasit Phowthongkum
Thyroid cancer (TC) is a known extra-intestinal manifestation and contributes to the mortality and morbidity in patients with familial adenomatous polyposis (FAP). Its exact prevalence is not well established and recent studies have shown an increasing number of TC in this patient population. The prevalence of benign thyroid masses and endocrinologic thyroid disorders are also poorly described. We conducted a systematic review and meta-analysis by using a random-effects model to characterize TC and estimated the prevalence of thyroid diseases in FAP patients...
April 16, 2018: Familial Cancer
https://www.readbyqxmd.com/read/29662307/thyroid-nodules-in-centenarians-prevalence-and-relationship-to-lifestyle-characteristics-and-dietary-habits
#5
Yao Yao, Xianghui Chen, Shengzheng Wu, Liang Guo, Hao Zhang, Qiao Zhu, Jie Tang, Fuxin Luan, Yali Zhao, Faqin Lv, Yao He
Background: Thyroid nodules (TNs) are common thyroid lesions in older population. Few studies have focused on the prevalence of TNs and their relationship to lifestyle characteristics and dietary habits in centenarians. The current study aimed at determining the prevalence of TNs in Chinese centenarians by using high-resolution ultrasound (US) equipment and at investigating its relationship to lifestyle characteristics and dietary habits. Participants and methods: The current study was part of the China Hainan Centenarian Cohort Study that was conducted in Hainan, an iodine-sufficient region in People's Republic of China...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29662266/thyroid-nodules-and-long-term-follow-up-among-childhood-cancer-survivors-who-underwent-hematopoietic-stem-cell-transplantation
#6
Shunsuke Shimazaki, Itsuro Kazukawa, Maine Ishida, Masanori Minagawa
Thyroid nodules have been observed in childhood cancer survivors (CCS) treated with chemotherapy and radiotherapy. We report four patients with thyroid nodules identified during the long-term follow-up of children who underwent hematopoietic stem cell transplantation (HSCT). The thyroid nodules were diagnosed as adenomatous goiter in all four patients. The interval between the primary cancer diagnosis and the occurrence of the thyroid nodules was more than 10 yr. Furthermore, all four patients underwent HSCT in conditioning with total body irradiation (TBI) before the age of 10 yr...
2018: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
https://www.readbyqxmd.com/read/29658835/sonographic-features-of-multifocal-papillary-thyroid-carcinomas
#7
Dong Wook Kim, Gi Won Shin, Yoo Jin Lee, Soo Jin Jung, Hye Jin Baek, Taewoo Kang
OBJECTIVE: It is uncertain whether papillary thyroid carcinomas (PTCs) of the same subtype display similar sonographic features. This retrospective analysis of pre-operative sonographic and pathologic findings aimed to assess whether PTCs of the same subtype share sonographic features. METHODS: Before undergoing thyroid surgery, 137 patients underwent ultrasound (US) examination. A single radiologist used a picture archiving and communication system and pathologic reports to investigate all sonographic features of the largest and second largest PTCs...
April 2018: Endocrine Practice
https://www.readbyqxmd.com/read/29658805/subclinical-hypothyroidism-is-not-a-risk-factor-for-polycystic-ovary-syndrome-in-obese-women-of-reproductive-age
#8
Bingjie Zhang, Jing Wang, Shanmei Shen, Jiayi Liu, Jie Sun, Tianwei Gu, Dalong Zhu, Yan Bi
Obese women are at high risk for polycystic ovary syndrome (PCOS). Subclinical hypothyroidism (SCH) has been associated with weight gain, insulin resistance and impaired fertility, which are also factors involved in PCOS. However, there is limited information regarding the influence of SCH on the presence of PCOS. In order to determine whether SCH increases the prevalence of PCOS, we performed a cross-sectional study in a cohort of reproductive-aged obese women. All subjects underwent anthropometric evaluation, laboratory tests and ultrasound examination...
April 16, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29650270/radioiodine-refractory-differentiated-thyroid-cancer
#9
REVIEW
Yuchen Jin, Douglas Van Nostrand, Lingxiao Cheng, Min Liu, Libo Chen
Differentiated thyroid cancer (DTC) is usually curable with surgery, radioactive iodine (RAI), and thyroid-stimulating hormone (TSH) suppression. However, local recurrence and/or distant metastases occur in approximately 15% of cases during follow-up, and nearly two-thirds of these patients will become RAI-refractory (RR-DTC) with a poor prognosis. This review focuses on the most challenging and rapidly evolving aspects of RR-DTC, and we discuss the considerable improvement in more accurately defining RR-DTC, more effective therapeutic strategies, and describe the diagnosis, pathogenesis, and future prospects of RR-DTC...
May 2018: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/29642533/rhabdomyolysis-in-a-young-girl-with-van-wyk-grumbach-syndrome-due-to-severe-hashimoto-thyroiditis
#10
Alberto Leonardi, Laura Penta, Marta Cofini, Lucia Lanciotti, Nicola Principi, Susanna Esposito
Background: Autoimmune hypothyroidism (Hashimoto thyroiditis; HT) is the most common postnatal thyroid disease. Clinical manifestations of HT vary according to disease severity. Due to the pleiotropic effects of thyroid hormone, less common signs and symptoms of HT can occur, leading to a delay in diagnosis. Case presentation: A 9-year-old girl of Indian origin was admitted for a one-week history of widespread myalgia, fatigue, muscle weakness, difficulty walking, and a significant increase in weight (approximately 2 kg) without any changes in daily habits...
April 9, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29627743/the-value-of-shear-wave-elastography-in-diffuse-thyroid-disease
#11
Jianxue Liu, Yaoren Zhang, Yonghao Ji, Qinyun Wan, Guoliang Dun
PURPOSE: The aim of this study is to discuss the value of ultrasound-based shear wave™ elastography (SWE) in diffuse thyroid disease (DTD). METHOD: Thyroid stiffness in 154 patients with DTD and 30 normal subjects was measured by SWE. The serum indicators of all subjects were detected. RESULTS: The area under the receiver operating characteristic (AUROC) curve for DTD by SWE was 0.852. The AUROCs of SWE for differentiating chronic autoimmune thyroiditis (CAT) from Graves' disease (GD) and subacute thyroiditis (SAT) were 0...
March 29, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29626008/differences-between-ata-aace-ace-ame-and-acr-ti-rads-ultrasound-classifications-performance-in-identifying-cytological-high-risk-thyroid-nodules
#12
Angelo Lauria, Ernesto Maddaloni, Silvia Irina Briganti, Giuseppina Beretta Anguissola, Eleonora Perrella, Chiara Taffon, Andrea Palermo, Paolo Pozzilli, Silvia Manfrini, Anna Crescenzi
OBJECTIVE: Thyroid ultrasound is crucial for clinical decision in the management of thyroid nodules. In this study we aimed to estimate and compare the performance of ATA, AACE/ACE/AME and ACR TI-RADS ultrasound classifications in discriminating nodules with high-risk cytology. DESIGN: Cross sectional study Methods 1077 thyroid nodules undergoing fine needle aspiration were classified according to ATA, AACE/ACE/AME and ACR TI-RADS ultrasound classifications by an automated algorithm...
April 6, 2018: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29620644/intrathyroidal-ectopic-thymus-in-children-a-benign-lesion
#13
Myung Hoon Bang, JinShik Shin, Kwan Seop Lee, Min Jae Kang
As ultrasound is commonly used these days, more and more lesions are found incidentally, including simple cysts, isoechoic nodules, and hypoechoic nodules, such as ectopic thymus. We here report the prevalence of ectopic thymus and its natural course.We retrospectively reviewed the charts of 690 subjects (342 males, 348 females) who were under 18 years old and had undergone neck or thyroid ultrasound at Hallym University Sacred Heart Hospital from January 2014 to June 2017. Ectopic thymus was defined when the incidental lesion was hypo- to iso-echoic compared to adjacent muscles with vascularity and did not have a connection to the thymus in the mediastinum...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29619406/unique-cytologic-features-of-thyroiditis-caused-by-immune-checkpoint-inhibitor-therapy-for-malignant-melanoma
#14
Trevor E Angell, Le Min, Tad J Wieczorek, F Stephen Hodi
Blockade of immune checkpoint molecules to reverse cancer-induced immune suppression can improve anti-tumor immune responses in cancer patients. Monoclonal antibodies targeting two such molecules, Programmed cell death protein 1 (PD-1) and cytotoxic T-lymphocyte associated protein 4 (CTLA-4) have shown clinical benefit in the treatment of advanced malignancies, including metastatic melanoma. Adverse effects of these immune checkpoint inhibitors include immune-related adverse events (irAE) and the inducing of new autoimmunity, of which one of the most common is autoimmune thyroiditis...
March 2018: Genes & Diseases
https://www.readbyqxmd.com/read/29619107/unusual-presentation-of-differentiated-thyroid-cancer-metastasis
#15
Haissan Iftikhar, Mubasher Ikram, Adnan Yar Muhammad, Karim Rizwan Nathani
Introduction  The rates of thyroid cancers are on a rise, especially well-differentiated thyroid cancers. This could be partly due to newer diagnostic modalities, like high-resolution ultrasound, that can pick up smaller lesions. Differentiated thyroid cancers with distant metastases are not common, and even rarer is the initial presentation with complaints not related to the neck. Objectives  The objective of this series was to study and report the unusual cases of patients with differentiated thyroid cancer with distant metastasis...
April 2018: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29610616/ovarian-strumal-carcinoid-tumour-case-report
#16
Vesna S Antovska, Milka Trajanova, Iskra Krstevska, Irena Gosheva, Jasmina Chelebieva, Irina Prodanova
BACKGROUND: Ovarian strumal carcinoid is a germ cell tumour characterised by a mixture of thyroid tissue and carcinoid. Ovarian struma is a very rare occurrence with 0.3-1% incidence of all ovarian tumours and 3% of mature teratomas. Primary carcinoid ovarian tumours are still uncommon as a part of mature teratoma or mucinous cystadenoma. There are four major variants of a carcinoid tumour: insular, trabecular, strumal and mucinous. A strumal carcinoid is an unusual form of ovarian teratoma composed of an intimate admixture of thyroid/carcinoid tissues...
March 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29608439/quantitative-analysis-of-the-benefits-and-risk-of-thyroid-nodule-evaluation-in-patients-%C3%A2-70-years-old
#17
Zhihong Wang, Chirag M Vyas, Olivia Van Benschoten, Matt A Nehs, Francis D Moore, Ellen Marqusee, Jeffrey F Krane, Matthew I Kim, Howard T Heller, Atul A Gawande, Mary C Frates, Peter M Doubilet, Gerard M Doherty, Nancy L Cho, Edmund S Cibas, Carol B Benson, Justine A Barletta, Ann Marie Zavacki, P Reed Larsen, Erik K Alexander, Trevor E Angell
BACKGROUND: In older patients, thyroid nodules are frequently detected and referred for evaluation, though usually prove to be benign disease or low-risk cancer. Therefore, management should be guided not solely by malignancy risk, but also by the relative risks of any intervention. Unfortunately, few such data are available for patients ≥70 years old. METHODS: All consecutive patients ≥70 years old assessed by ultrasound (US) and fine-needle aspiration (FNA) between 1995 and 2015 were analyzed...
April 2, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29607563/investigation-of-thyroid-nodules-a-practical-algorithm-and-review-of-guidelines
#18
REVIEW
Jin Soo A Song, Adam A Dmytriw, Eugene Yu, Reza Forghani, Lorne Rotstein, David Goldstein, Colin S Poon
BACKGROUND: High resolution ultrasound has led to early detection of subclinical tumors and drastic increase in incidence of thyroid malignancy. To achieve a balance in appropriate investigation without perpetuating an overdiagnosis phenomenon, a concise set of evidence-based recommendations to stratify risk is required. METHODS: We sought to assemble an evidence-based diagnostic algorithm and accompanying pictorial review for workup of thyroid nodules that summarizes the most recent guidelines...
April 1, 2018: Head & Neck
https://www.readbyqxmd.com/read/29603330/a-clinical-decision-support-system-using-ultrasound-textures-and-radiologic-features-to-distinguish-metastasis-from-tumor-free-cervical-lymph-nodes-in-patients-with-papillary-thyroid-carcinoma
#19
Ali Abbasian Ardakani, Reza Reiazi, Afshin Mohammadi
OBJECTIVES: This study investigated the potential of a clinical decision support approach for the classification of metastatic and tumor-free cervical lymph nodes (LNs) in papillary thyroid carcinoma on the basis of radiologic and textural analysis through ultrasound (US) imaging. METHODS: In this research, 170 metastatic and 170 tumor-free LNs were examined by the proposed clinical decision support method. To discover the difference between the groups, US imaging was used for the extraction of radiologic and textural features...
March 30, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29596300/quantitative-assessment-of-thyroid-submandibular-and-parotid-glands-elasticity-with-shear-wave-elastography-in-children
#20
Hatice Arioz Habibi, Emine Sebnem Memis Durmaz, Vusale Qarayeva, Sedat Giray Kandemirli, Ayse Kalyoncu Ucar, Mine Aslan, Gozde Apaydin, Sebuh Kurugoglu, Ibrahim Adaletli
Tissue elasticity is becoming a more commonly used parameter in evaluation of parenchyma in inflammatory diseases. Considering the changes in the thyroid and salivary glands with adolescence, determination of mean elasticity ranges with a function of age is necessary to apply ultrasound elastography more widely in the pediatric population.The thyroid, submandibular, and parotid glands of 127 healthy volunteers (66 males, 61 females; mean age = 10.3 ± 3.9 years; range = 3-17 years) were evaluated with shear-wave elastography...
March 29, 2018: Ultrasound Quarterly
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