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Thyroid Ultrasound

Kai Pun Wong, Kin Pan Au, Shi Lam, Brian H Lang
INTRODUCTION: Patients with hoarseness of voice, previous neck operation or suspicion of malignancy are at "high-risk" of having pre-thyroidectomy vocal cord (VC) palsy. Therefore, VC functions should be evaluated before the operation. We aimed to evaluate the accuracy of hoarseness, voice related questionnaire (Voice handicap Index (VHI) - 30) and transcutaneous laryngeal ultrasound (TLUSG) in diagnosing VC palsy, as well as the role of TLUSG in the evaluation of high-risk patients. METHODS: 1000 patients undergoing thyroidectomy or other endocrine-related neck procedures were prospectively included...
October 20, 2016: Thyroid: Official Journal of the American Thyroid Association
Ming-Hsun Wu, Chiung-Nien Chen, Kuen-Yuan Chen, Ming-Chih Ho, Hao-Chih Tai, Yu-Hsin Wang, Argon Chen, King-Jen Chang
Hypoechogenicity has been described qualitatively and is potentially subject to intra- and inter-observer variability. The aim of this study was to clarify whether quantitative echoic indexes (EIs) are useful for the detection of malignant thyroid nodules. Overall, 333 participants with 411 nodules were included in the final analysis. Quantification of echogenicity was performed using commercial software (AmCAD-UT; AmCad BioMed, Taiwan). The coordinates of three defined regions, the nodule, thyroid parenchyma, and strap muscle regions, were recorded in the database separately for subsequent analysis...
October 20, 2016: Scientific Reports
Ljubica Fustar Preradovic, Davorin Danic, Radan Dzodic
Parathyroid cysts (PCs) account for less than 1% of all parathyroid lesions and are most commonly located along thyroid lobes, rarely at ectopic sites. PCs are important because they can pose a differential diagnostic challenge against other cystic formations of the neck. PCs can be functional (elevated serum parathyroid hormone level) and nonfunctional. Four cases of nonfunctional PCs are presented. All four female patients underwent physical examination and ultrasonography of the neck with ultrasound-guided fine-needle aspiration biopsy (UG-FNA)...
October 19, 2016: Endocrine Journal
Stephanie Rutledge, Michele Harrison, Martin O'Connell, Tadhg O'Dwyer, Maria M Byrne
BACKGROUND: We report the case of a giant intrathyroidal parathyroid adenoma weighing 59 g in a young woman presenting acutely with severe hypercalcemia requiring correction and adequate preoperative management prior to surgery. Parathyroid adenomas account for 85 % of cases of primary hyperparathyroidism. Those weighing more than 3.5g are classified as giant parathyroid adenomas. There are only 25 cases of parathyroid adenomas weighing over 30g reported in the literature. With the wide availability of biochemical screening tests in Western countries, mildly elevated calcium levels are often discovered incidentally...
October 19, 2016: Journal of Medical Case Reports
Alborz Jooya, Joe Saliba, Audrey Blackburn, Michael Tamilia, Michael P Hier, Alex Mlynarek, Véronique-Isabelle Forest, Louise Rochon, Anca Florea, Hangjun Wang, Richard J Payne
BACKGROUND: Management decisions are not straightforward when the Ultrasound Guided Fine Needle Aspiration (USFNA) demonstrates a Bethesda score of either category III or IV, and a diagnostic hemi-thyroidectomy or a repeat USFNA (r-USFNA) could be performed. The aim of this study is to assess the effectiveness of r-USFNA in the management of indeterminate thyroid nodules by evaluating the likelihood of obtaining a definite diagnosis. METHODS: We reviewed the medical records of all patients with thyroid nodules between 2011 and 2015 at the Jewish General Hospital (Montreal, Canada)...
October 18, 2016: Journal of Otolaryngology—Head & Neck Surgery
Javier López-Gómez, Ma Alejandra Salazar-Álvarez, Martin Granados-Garcia
INTRODUCTION: Thyroglosal duct cyst is a common anomaly with an incidence of 7% in adults, the rate of carcinoma in TGDC is 0.7-1.6%, and are extremely rare those originated in the hyoid bone. PRESENTATION OF CASE: A 60 years old male patient, had a hard mass in the anterior neck. CT revealed a hyoid tumor. Hyoid bone resection was performed, the pathological report show a conventional papillary carcinoma in bone tissue. We rule out primary tumor in thyroid gland...
September 29, 2016: International Journal of Surgery Case Reports
Xuemei Gao, Xiao Zhang, Yajing Zhang, Wenjuan Hua, Yusufu Maimaiti, Zairong Gao
The increasing detection of papillary thyroid microcarcinoma (PTMC) has created management dilemmas. To clarify the clinical significance of postsurgery stimulated thyroglobulin (ps-Tg) in PTMC who undergo thyroidectomy and radioactive iodine (RAI), we retrospectively reviewed the 358 PTMC patients who were treated with RAI and followed up in our hospital. Those with an excessive anti-Tg antibody, ultrasound-detected residual were excluded, thereby resulting in the inclusion of 280 cases. Their clinical and histopathological information and clinical outcomes were collected and summarized...
October 2016: Medicine (Baltimore)
Friedhelm Raue, Karin Frank-Raue
Thyroid cancer is the most common endocrine malignancy. Differentiated thyroid cancer (DTC) with the two subtypes, papillary thyroid cancer (PTC) and follicular thyroid cancer (FTC), is the most frequent subtype of thyroid cancer; more rare subtypes are medullary thyroid cancer (MTC) and anaplastic thyroid cancer (ATC). The incidence of DTC has increased rapidly in recent years due to the more frequent use of imaging methods such as ultrasound of the neck and fine-needle aspiration (FNA) of thyroid nodules...
October 15, 2016: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Michela Marina, Gian Paolo Ceda, Raffaella Aldigeri, Graziano Ceresini
To evaluate the causes of the first referral to an endocrine visit of patients with thyroid cancer in a mildly iodine-deficient area and to correlate them with prognostic features. We studied 298 consecutive patients (64 M and 234 F) with thyroid cancer. Of these, 281 had differentiated thyroid cancer. The causes of referral were categorized as follows: (Group A) clinical evidence of a neck lump; (Group B) incidental imaging in subjects without known thyroid diseases; (Group C) incidental imaging during a workup of thyroid disorders...
October 14, 2016: Endocrine
Zahraa Al-Hilli, Veljko Strajina, Travis J McKenzie, Geoffrey B Thompson, David R Farley, M Regina Castro, Alicia Algeciras-Schimnich, Melanie L Richards
BACKGROUND: Papillary thyroid carcinoma (PTC) is frequently associated with cervical lymph node metastases. Guidelines recommend performing ultrasound-guided fine-needle aspiration cytology (FNAC) for suspicious nodes to guide management. No specific recommendations are available for the use of FNA thyroglobulin assay (FNA-Tg). This study investigated the diagnostic value of performing FNAC and FNA-Tg. METHODS: Patient demographics, preoperative investigations, surgery, and lymph node pathology were collected for patients with PTC who underwent lateral neck lymphadenectomy and central compartment reexploration from January 2000 to July 2015...
October 13, 2016: Annals of Surgical Oncology
Cafer Kaya, Abbas Ali Tam, Ahmet Dirikoç, Aylin Kılıçyazgan, Mehmet Kılıç, Şeyda Türkölmez, Reyhan Ersoy, Bekir Çakır
Objective: Primary hyperparathyroidism (PHP) is a common endocrine disease, and its most effective treatment is surgery. Postoperative hypocalcemia is a morbidity of parathyroid surgeries, and it may extend hospitalization durations. The purpose of this study is to determine the predictive factors related to the development of hypocalcemia and hungry bone syndrome (HBS) in patients who underwent parathyroidectomy for PHP. Materials and methods: Laboratory data comprising parathyroid hormone (PTH), calcium, phosphate, 25-OHD, albumin, magnesium, alkaline phosphatase (ALP), blood urea nitrogen (BUN), and thyroid stimulating hormone (TSH) of the patients were recorded preoperatively, on the 1st and 4th days postoperatively, and in the 6th postoperative month, and their neck ultrasound (US) and bone densitometry data were also recorded...
October 10, 2016: Archives of Endocrinology and Metabolism
Eleonora Horvath, Claudio F Silva, Sergio Majlis, Ignacio Rodriguez, Velimir Skoknic, Alex Castro, Hugo Rojas, Juan-Pablo Niedmann, Arturo Madrid, Felipe Capdeville, Carolina Whittle, Ricardo Rossi, Miguel Domínguez, Hernán Tala
OBJECTIVE: To assess performance of TIRADS classification on a prospective surgical cohort, demonstrating its clinical usefulness. METHODS: Between June 2009 and October 2012, patients assessed with pre-operative ultrasound (US) were included in this IRB-approved study. Nodules were categorised according to our previously described TIRADS classification. Final pathological diagnosis was obtained from the thyroidectomy specimen. Sensitivity, specificity, positive/negative predictive values and likelihood ratios were calculated...
October 7, 2016: European Radiology
Giriraj K Sharma, Robert A Sofferman, William B Armstrong
OBJECTIVES/HYPOTHESIS: The American College of Surgeons Thyroid and Parathyroid Ultrasound Skills-Oriented Course (TPUSC) was designed to teach surgeons how to interpret and perform office-based head and neck ultrasound (HNUS). The objective of this study was to survey attendees of the TPUSC to evaluate the usefulness of the course, to track surgeon performed HNUS practice patterns, and to help identify potential roadblocks to incorporation of HNUS into a surgeon's practice. STUDY DESIGN: Cross-sectional survey...
September 26, 2016: Laryngoscope
Abdulwahid M Salih, F H Kakamad, Han Aube
INTRODUCTION: Insular carcinoma of thyroid (ICT) is a rare pattern of thyroid tumor. Being hyperfunctioning makes the condition rarer. Here we reported a case of ICT associated with hyperthyroidism. CASE REPORT: A 65-year-old female presented with neck mass for 4 years. She had symptoms of thyrotoxicosis and received antithyroid treatment. She was referred for surgical management. She had multiple, non tender, mobile masses in the neck. Ultrasound showed midline multiple heterogenous mass lesions with multiple lymph nodes in right side of the neck largest one measuring 2×2cm...
October 1, 2016: International Journal of Surgery Case Reports
Andrea M Isidori, Vito Cantisani, Elisa Giannetta, Daniele Diacinti, Emanuele David, Valerio Forte, Daniela Elia, Corrado De Vito, Emilia Sbardella, Daniele Gianfrilli, Francesco Monteleone, Jessica Pepe, Salvatore Minisola, Giorgio Ascenti, Vito D'Andrea, Carlo Catalano, Ferdinando D'Ambrosio
To evaluate the accuracy of ultrasound elastography with Elastoscan(TM) Core Index in the differential diagnosis of parathyroid lesions from ectopic thyroid nodules and lymph nodes. Seventy nine patients with repeatedly high levels of circulating intact parathyroid hormone, normal vitamin D and renal function tests, with an ultrasound scan showing a neck lesion, sharply demarcated from the thyroid lobules, were consecutively enrolled. Ultrasound with and without Color Doppler and ultrasound elastography were performed before histological examination...
October 5, 2016: Endocrine
Agnaldo J Graciano, Carlos A Fischer, Carlos T Chone, Giuliano S Bublitz, Marina Sonagli, Cezar A Rodrigues Filho
BACKGROUND: There are a growing number of thyroid ultrasound courses to train endocrinologists, pathologists, and surgeons to perform ultrasound-guided fine-needle aspiration (FNA). However, there are limited data to support the efficacy of ultrasound-guided FNA performed by nonradiologists. METHODS: We compared the efficacy of ultrasound-guided FNA performed by surgeons newly trained in thyroid ultrasound with that of the same technique performed by 1 experienced radiologist...
October 5, 2016: Head & Neck
Ji Hye Lee, Hyun Joo Shin, Jung Hyun Yoon, Eun-Kyung Kim, Hee Jung Moon, Hye Sun Lee, Hyeong Ju Kwon, Jin Young Kwak
BACKGROUND: For patients with papillary thyroid carcinoma (PTC), lymph node metastasis is associated with an increased recurrence rate. The purpose of this study was to investigate whether the vascular endothelial growth factor (VEGF), microvessel density (MVD), and vascular index (VI) can predict lymph node metastasis in patients with PTC. METHODS: From January 2011 to October 2011, 202 patients with PTCs underwent preoperative staging ultrasound evaluation. To evaluate vascularity, we measured the VI, VEGF expression, and MVD...
October 5, 2016: Head & Neck
Giovanni Mauri, Luca Cova, Cristian Giuseppe Monaco, Luca Maria Sconfienza, Sabrina Corbetta, Stefano Benedini, Federico Ambrogi, Valentina Milani, Alberto Baroli, Tiziana Ierace, Luigi Solbiati
PURPOSE: To evaluate the reduction over time of benign thyroid nodules treated using percutaneous laser ablation (PLA) and radiofrequency ablation (RFA) by the same equipe. MATERIALS AND METHODS: Ninety patients (age 55.6±14.1 years) underwent ablation for benign thyroid nodule causing compression/aesthetic dissatisfaction from 2011. Fifty-nine (age 55.8±14.1 years) underwent RFA and 31 (age 55.2±14.2 years) PLA, ultrasound guided. Technical success, complications, duration of ablation and treatment, energy deployed, volumetric percentage reduction at 1, 6, and 12 months were derived...
October 4, 2016: International Journal of Hyperthermia
Bo Li, Yaqiong Zhang, Ping Yin, Jian Zhou, Tian'an Jiang
The present study aimed to investigate the value of ultrasonography in the diagnosis of papillary thyroid microcarcinoma (PTMC) coexisting with a thyroid abnormality, and to improve the accuracy of PTMC diagnosis. The ultrasonic features of 38 PTMC nodules coexisting with a thyroid abnormality and 56 thyroid benign nodules, obtained by surgical resection and confirmed by pathological analysis, were retrospectively analyzed. All masses were ≤ 1.0 cm in diameter. Ultrasonic features that were analyzed included the shape, aspect ratio, boundary, margin, echo, uniformity, presence or absence of microcalcification and enlargement of the lymph nodes, as well as the blood flow of the nodules...
October 2016: Oncology Letters
Koji Morita, Takahiko Sakamoto, Shuji Ota, Hideo Masugi, Ikumi Chikuta, Yamato Mashimo, Naoki Edo, Takuo Tokairin, Nobuhiko Seki, Toshio Ishikawa
It has been shown that metastases to the thyroid from extrathyroidal malignancies occur as solitary or multiple nodules, or may involve the whole thyroid gland diffusely. However, diffuse metastasis of gastric cancer to the thyroid is extremely rare. Here, we report a case of a 74-year-old woman with diffuse infiltration of gastric adenocarcinoma (signet-ring-cell carcinoma/poorly differentiated adenocarcinoma) cells in the thyroid. The pathological diagnosis was made based on upper gastrointestinal endoscopy with biopsy and fine-needle aspiration cytology of the thyroid...
October 1, 2016: Journal of Medical Ultrasonics
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