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https://www.readbyqxmd.com/read/28813123/pharmacotherapy-for-hypertension-in-adults-aged-18-to-59-years
#1
REVIEW
Vijaya M Musini, Francois Gueyffier, Lorri Puil, Douglas M Salzwedel, James M Wright
BACKGROUND: Hypertension is an important risk factor for adverse cardiovascular events including stroke, myocardial infarction, heart failure and renal failure. The main goal of treatment is to reduce these events. Systematic reviews have shown proven benefit of antihypertensive drug therapy in reducing cardiovascular morbidity and mortality but most of the evidence is in people 60 years of age and older. We wanted to know what the effects of therapy are in people 18 to 59 years of age...
August 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28813122/morphological-alterations-in-the-jejunal-mucosa-of-aged-rats-and-the-possible-protective-role-of-green-tea
#2
Zeinab Abel-Rehim Hassan, Agata Zauszkiewicz-Pawlak, Shaimaa A Abdelrahman, Sami Algaidi, Maha Desouky, Sally M Shalaby
INTRODUCTION: Gastrointestinal disorders become more prevalent with ageing. This study is aimed to describe morphological changes that occur in the jejunal mucosa of male albino rats as a result of ageing and the protective effect of green tea supplements. MATERIAL AND METHODS: The experiment was performed on sixty rats: thirty young-adult (6-month old, body mass 200-220 g) and thirty old (24-month-old, body mass 220-260 g) animals. Each group was further divided into two subgroups (n = 15 each): control rats and green tea-treated rats that received 1...
August 16, 2017: Folia Histochemica et Cytobiologica
https://www.readbyqxmd.com/read/28813110/trait-vs-state-anxiety-in-different-threatening-situations
#3
Pollyana Caldeira Leal, Tiago Costa Goes, Luiz Carlos Ferreira da Silva, Flavia Teixeira-Silva
Objective: Anxiety as a uni- or multidimensional construct has been under discussion. The unidimensional approach assumes that there is a general trait anxiety, which predisposes the individuals to increases in state anxiety in various threatening situations. In this case, there should be a correlation between state and trait anxiety in any situation of threat. Therefore, the aim of this study was to investigate the correlation between trait and state anxiety in participants exposed to two different anxiogenic situations: interpersonal threat (Video-Monitored Stroop Test - VMST) and physical threat (third molar extraction - TME)...
August 14, 2017: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/28813109/assessment-of-inhibitory-control-in-crack-and-or-cocaine-users-a-systematic-review
#4
Fernanda Rasch Czermainski, Alice Rodrigues Willhelm, Álvaro Zaneti Santos, Mayra Pacheco Pachado, Rosa Maria Martins de Almeida
Objective: Impairments involving inhibitory control have been considered central deficits in drug users, but it appears that dysfunctions may be specific to users' drug of choice. This article aims to review recent findings on inhibitory control impairment in samples of crack and/or cocaine users. Methods: Searches were conducted on the PubMed, PsycINFO, and Web of Knowledge databases in two stages according to eligibility criteria. Initially, databases were searched and the titles and abstracts of results were analyzed and then selected articles were read in full...
August 14, 2017: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/28813107/climatic-characteristics-of-the-2010-2016-drought-in-the-semiarid-northeast-brazil-region
#5
José A Marengo, Lincoln M Alves, Regina C S Alvala, Ana Paula Cunha, Sheila Brito, Osvaldo L L Moraes
This study discusses the climatological aspects of the most severe drought ever recorded in the semiarid region Northeast Brazil. Droughts are recurrent in the region and while El Nino has driven some of these events others are more dependent on the tropical North Atlantic sea surface temperature fields. The drought affecting this region during the last 5 years shows an intensity and impact not seen in several decades in the regional economy and society. The analysis of this event using drought indicators as well as meteorological fields shows that since the middle 1990s to 2016, 16 out of 25 years experienced rainfall below normal...
August 14, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28813102/terpene-esters-from-natural-products-synthesis-and-evaluation-of-cytotoxic-activity
#6
Mauricio M Victor, Jorge M David, Maria C K Sakukuma, Letícia V Costa-Lotufo, Andrea F Moura, Ana J Araújo
Natural steroids and triterpenes such as b-sitosterol, stigmasterol, lupeol, ursolic and betulinic acids were transformed into its hexanoic and oleic esters, to evaluate the influence of chemical modification towards the cytotoxic activities against tumor cells. The derivatives were evaluated against five tumor cell lines [OVCAR-8 (ovarian carcinoma); SF-295 (glioblastoma); HCT-116 (colon adenocarcinoma); HL-60 (leukemia); and PC-3 (prostate carcinoma)] and the results showed only betulinic acid hexyl ester exhibits cytotoxic potential activity...
August 14, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28813101/forage-potential-of-native-ecotypes-of-paspalum-notatum-and-p-guenoarum
#7
Marcelo G Steiner, Miguel Dall'agnol, Carlos Nabinger, Simone M Scheffer-Basso, Roberto L Weiler, Carine Simioni, Maria Teresa Schifino-Wittmann, Éder A M DA Motta
The Paspalum genus includes several species that are important for livestock in Rio Grande do Sul, such as P. notatum and P. guenoarum, typical of native pastures of the Pampa biome. The aim of this study was to investigate forage production and chemical composition of four ecotypes of these species in relation to the cv. 'Pensacola' (P. notatum). Ecotypes of P. guenoarum (Azulão and Baio) and P. notatum (André da Rocha and Bagual) and the cv. 'Pensacola' were evaluated for two years, during which four cuts/year were made...
August 14, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28813097/avian-communities-in-the-amazonian-cangas-vegetation-biogeographic-affinities-components-of-beta-diversity-and-conservation
#8
Sérgio H Borges, Marcos P D Santos, Leonardo M S Soares, Antonita S DA Silva
The Amazonian cangas is a vegetation type distributed as patches of open vegetation embedded in a matrix of tropical forest and that grows over iron-rich soils in the Serra dos Carajás region. To characterize cangas avifauna, we surveyed birds in eight patches varying from 43 to 1,366 hectares. Cangas avifauna has compositional affinities with savannas widespread throughout the Amazon and other biomes, and we estimate that more than 200 bird species occurs in this habitat. Species composition was relatively homogeneous, and the similarity among cangas patches was the dominant component of the beta-diversity...
August 14, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28813095/evaluation-of-cell-proliferation-and-endometrial-thickness-of-bitches-in-different-periods-of-diestrus
#9
Vanessa S A Gossler, Francislaine A G Santos, Aline R DE Azevedo, Priscila C Gonçalves, Hugo A Rigolo, Cleonice Trevisan, Ana Paula B Masseno, Ana Paula M M Cardoso, Paula C Papa, Caliê Castilho, Ines C Giometti
This study aimed to determine the histological features of the endometrium of bitches, as well as the cell proliferation at specific moments of diestrus, 10, 20, 30, 40, 50 and 60 days post ovulation, correlating the endometrial thickness with the uterine cell proliferation and the metabolic state (weight, blood glucose and plasma cholesterol) of the animals. Therefore, the right and left uterine horns of 26 clinically healthy bitches submitted to ovariohysterectomy were histologically analyzed 10, 20, 30, 40, 50 and 60 days post ovulation...
August 14, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28813093/where-is-sugarcane-cropping-expanding-in-the-brazilian-cerrado-and-why-a-case-study
#10
Murilo R DE Arruda, Ken E Giller, Maja Slingerland
Sugarcane growing area in Brazil sharply expanded between 2000 and 2010 due to the increasing world demand for sugar and ethanol. Since this expansion of sugarcane is said to occur in areas covered by degraded pastures, it is likely not threatening the environment or food production. In order to verify this assumption, we investigate at farm and field levels which types of land use sugarcane cropping replaced between 2005 and 2010 and the reasons for farmers shifting or not shifting to sugarcane, as a case study in two counties in the state of Goiás...
August 14, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28813091/guillain-barr%C3%A3-syndrome-celebrating-a-century
#11
Marcos R G de Freitas, Cecília M Vidal, Marco Orsini
A hundred years ago, Guillain, Barré and Strohl described a syndrome with a predominant motor acute or subacute polyneuritis, albumin-cytologic dissociation in the cerebrospinal fluid, and a benign course. Before them, many other authors, such as Landry, Duménil, Osler, and Grainger Stewart had described similar cases although they had not performed lumbar punctures. In this work, we outline certain features of the beginning of this famous syndrome.
August 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28813088/cognitive-dysfunction-in-corticobasal-degeneration
#12
Laís Machado de Oliveira, Igor Barcellos, Hélio A G Teive, Renato Puppi Munhoz
Corticobasal degeneration (CBD) was originally described as a distinct clinicopathological entity in 1967. Since then, different phenotypic presentations have emerged as possible manifestations of CBD histopathological findings. In addition, pathophysiological findings and the molecular basis have been delineated and several aspects of its cognitive manifestations have been clarified. Thus, not only the spectrum of what is currently designated as CBD has expanded, but overlap with other degenerative and even secondary disorders has made clinical diagnostic certainty even more challenging in the absence of specific and readily-available markers...
August 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28813079/diffusion-tensor-imaging-of-brain-white-matter-in-huntington-gene-mutation-individuals
#13
Roberta Arb Saba, James H Yared, Thomas M Doring, Med Phys, Vanderci Borges, Henrique Ballalai Ferraz
Objective: To evaluate the role of the involvement of white matter tracts in huntingtin gene mutation patients as a potential biomarker of the progression of the disease. Methods: We evaluated 34 participants (11 symptomatic huntingtin gene mutation, 12 presymptomatic huntingtin gene mutation, and 11 controls). We performed brain magnetic resonance imaging to assess white matter integrity using diffusion tensor imaging, with measurement of fractional anisotropy...
August 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28813075/violence-in-schools-and-the-voice-of-teachers
#14
Rodrigo Dornelas, Thaynara Alves Dos Santos, Daniela Sena de Oliveira, Roxane de Alencar Irineu, Aline Brito, Kelly Silva
Purpose: To correlate self-reporting of voice disorders with habits that impact voice production and situations of violence experienced by teachers. Methods: The study involved 41 elementary-school teachers of rural and urban areas. Two instruments were used for data collection: The Vocal Production Condition - Teacher (CPV-P) questionnaire and the Screening Index for Voice Disorders - ITDV. The chi-square test was used to verify association among variables with a significance level of 5%...
August 10, 2017: CoDAS
https://www.readbyqxmd.com/read/28813074/oral-narrative-of-individuals-with-fetal-alcohol-spectrum-disorder
#15
Giulia Ganthous, Natalia Freitas Rossi, Célia Maria Giacheti
Purpose: To investigate and compare the oral narrative of individuals with FASD and individuals with typical language development (TLD), as well as to correlate the narrative performance with the score from 4-Digit Diagnostic Code. Methods: Participants were 20 individuals with FASD, of both genders, with chronological age between 6 and 16 years, and 20 individuals with TLD, same gender and similar to the FASD group in age and socioeconomic status. The oral narrative was elicited using the book Frog, where are you? and the data were analyzed in terms of macrostructure, microstructure and global coherence level...
August 10, 2017: CoDAS
https://www.readbyqxmd.com/read/28813073/functional-health-literacy-and-quality-of-life-of-high-school-adolescents-in-state-schools-in-belo-horizonte
#16
Poliana Cristina Rocha, Dálian Cristina Rocha, Stela Maris Aguiar Lemos
Purpose: To investigate the association between functional health literacy and sociodemographic factors, quality of life, self-perception of health, and perception of contexts of violence in adolescents in state schools in Belo Horizonte. Methods: This is a cross-sectional analytical observational study with a probabilistic sample of 384 adolescents between 15 and 19 years old. Data collection was carried out in schools and included self-reporting questionnaires to assess the functional health literacy, socioeconomic classification, self-perceived health, and quality of life...
August 10, 2017: CoDAS
https://www.readbyqxmd.com/read/28813071/content-validation-clarity-relevance-reliability-and-internal-consistency-of-enunciative-signs-of-language-acquisition
#17
Anelise Henrich Crestani, Anaelena Bragança de Moraes, Ana Paula Ramos de Souza
Purpose: To analyze the results of the validation of building enunciative signs of language acquisition for children aged 3 to 12 months. Methods: The signs were built based on mechanisms of language acquisition in an enunciative perspective and on clinical experience with language disorders. The signs were submitted to judgment of clarity and relevance by a sample of six experts, doctors in linguistic in with knowledge of psycholinguistics and language clinic. In the validation of reliability, two judges/evaluators helped to implement the instruments in videos of 20% of the total sample of mother-infant dyads using the inter-evaluator method...
August 10, 2017: CoDAS
https://www.readbyqxmd.com/read/28813067/total-syntheses-of-smenothiazoles-a-and-b
#18
Xiao Ma, Yajie Chen, Sigui Chen, Zhengshuang Xu, Tao Ye
Concise total syntheses of smenothiazoles A (1) and B (2), two distinguished vinyl chloride containing natural products isolated from the marine sponge S. aurea, have been developed. Silastannation, Stille reaction and a carefully controlled desilylchlorination were employed as key steps to construct unique polyketide acid fragments, and the optimized reaction conditions avoided migration of 2,5-diene to a 2,4-conjugated system. This report unambiguously confirmed the structures of both natural products.
August 16, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28813066/multivalent-mesoporous-silica-nanoparticles-photo-delivering-nitric-oxide-with-carbon-dots-as-fluorescence-reporters
#19
Damien Afonso, Sabrina Valetti, Aurore Fraix, Claudia Bascetta, Salvatore Petralia, Sabrina Conoci, Adam Feiler, Salvatore Sortino
Amino-terminated mesoporous silica nanoparticles embedding carbon dots (MSCD) formed by calcination were functionalized with a nitric oxide (NO) photodonor (1) to give a robust MSCD-1 conjugate. The intense fluorescence of MSCDs was strongly quenched in MSCD-1 by effective energy transfer. Visible light excitation of MSCD-1 liberates NO, suppresses the energy transfer mechanism and leads to concomitant fluorescence restoration of the MSCD scaffold, which acts as an optical reporter for the released NO. The MSCD-1 hybrid is also able to encapsulate the highly hydrophobic photosensitizer temoporfin, preserving the fluorescence reporting function...
August 16, 2017: Nanoscale
https://www.readbyqxmd.com/read/28813063/tuning-mass-transport-in-magnetic-nanoparticle-filled-viscoelastic-hydrogels-using-low-frequency-rotating-magnetic-fields
#20
Shahab Boroun, Faïçal Larachi
This study investigates the response of magnetic nanoparticles (MNPs), dispersed in a viscoelastic hydrogel, to an external rotating magnetic field (RMF) for the purpose of developing a new class of magneto-responsive materials with tunable mass transport properties. Ferrogels were prepared by chemical cross-linking and polymerization of acrylamide in colloidal dispersions of thermally blocked MNPs of cobalt ferrite. Magnetization measurements of ferrogels in a swollen state revealed a transitional state from ferromagnetism to superparamagnetism through the shrinkage of hysteresis loops and the reduction of remanent magnetization...
August 16, 2017: Soft Matter
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