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https://www.readbyqxmd.com/read/29777786/photoselective-vaporisation-of-the-bladder-for-the-management-of-radiation-cystitis-technique-and-initial-outcomes
#1
Claire Pascoe, Daniel Christidis, Todd Manning, Benjamin W Lamb, Declan G Murphy, Nathan Lawrentschuk
Objective To describe our technique utilising photoselective vaporisation of the bladder (PVB) for the management of haemorrhagic cystitis and initial results of 12 patients. Materials and Method An audit of theatre records of a single surgeon was performed to identify patients who had undergone PVB for management of radiation-cystitis. TECHNIQUE: Rigid cystoscopy was performed. Ureteric catheters were placed and active bleeding sites targeted to optimise vision. Ablation was commenced using the vaporize function...
May 16, 2018: Urology
https://www.readbyqxmd.com/read/29748226/adolescent-with-intermittent-haematuria
#2
Roberto Pillon, Marco Pennesi, Ingrid Rabach, Egidio Barbi
No abstract text is available yet for this article.
May 10, 2018: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/29735834/utility-of-genexpert-in-the-diagnosis-reliance-on-urine-microscopy-and-clinical-characteristics-of-genitourinary-tuberculosis-at-a-tertiary-care-hospital
#3
Ajaz Nabi Koul, Basharat A Kassana, Aadil Rafeeq Rather
Background: One-third of the world's population is infected with tuberculosis (TB) with new infection occurring every second. In humans, TB is primarily caused by Mycobacterium tuberculosis(MTB). Genitourinary TB (GUTB) is still a major health problem in many developing countries including India and had been declared by the World Health Organisation as 'public health emergency' in 1993. Materials and Methods: This is a prospective study conducted at a tertiary care hospital involving 46 patients who presented with clinical feature suggestive of GUTB - urine specimens of these 46 patients were analysed for acid-fast bacilli (AFB), AFB culture, GeneXpert, and other relevant investigations were done to reach the diagnosis...
January 2018: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29722502/-diagnosis-of-urinary-schistosomiasis-by-identification-of-miracidia-of-schistosoma-haematobium
#4
Laura Zanisi, Pietro Benedetto Faré, Gabriele Poncini
Although rarely diagnosed in Switzerland, urinary tract schistosomiasis is common in the migrants' regions of origin, such as sub-Saharan Africa and the Middle East. Early recognition of this condition, even if asymptomatic, is crucial, because it increases the risk for HIV transmission and, if left untreated, can result in infertility and is associated with the development of bladder cancer. The diagnosis of urinary schistosomiasis should be especially suspected in case of terminal haematuria and eosinophilia in patients with a history of skin exposure to fresh water in endemic areas...
May 2, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29702097/can-renal-and-bladder-ultrasound-replace-ct-urogram-in-patients-investigated-for-microscopic-hematuria
#5
Wei Shen Tan, Rachael Sarpong, Pramit Khetrapal, Simon Rodney, Hugh Mostafid, Joanne Cresswell, James Hicks, Abhay Rane, Alastair Henderson, Dawn Watson, Jacob Cherian, Norman Williams, Chris Brew-Graves, Andrew Feber, John D Kelly
PURPOSE: Computed tomography urogram (CTU) is recommended when investigating patients with hematuria. We determine the incidence of urinary tract cancer and compare the diagnostic accuracy of CTU and renal and bladder ultrasound (RBUS) at identifying urinary tract cancer. METHODS: The DETECT I study (clinicaltrials.gov NCT02676180) is a prospective observational study recruiting patients ≥18 years following a presentation of macroscopic or microscopic haematuria at 40 hospitals...
April 24, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29700356/incidence-and-predictors-of-readmission-within-30-days-of-transurethral-resection-of-the-prostate-a-single-center-european-experience
#6
Franco Palmisano, Luca Boeri, Matteo Fontana, Andrea Gallioli, Elisa De Lorenzis, Stefano Paolo Zanetti, Gianluca Sampogna, Matteo Giulio Spinelli, Giancarlo Albo, Fabrizio Longo, Franco Gadda, Paolo Guido Dell'Orto, Emanuele Montanari
Hospital readmission rates have been analyzed due to their contribution to increasing medical costs. Little is known about readmission rates after urological procedures. We aimed to assess the incidence and predictors of 30-day readmission after discharge in patients treated with transurethral resection of the prostate (TURP). Data from 160 consecutive patients who underwent TURP from January 2015 to December 2016 were analysed. Intra hospitalization characteristics included length of stay (LOS), catheterization time (CT) and complications...
April 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29696665/using-the-chronic-kidney-disease-guidelines-to-evaluate-the-renal-safety-of-tenofovir-disoproxil-fumarate-in-hepatitis-b-patients
#7
H J Tsai, Y W Chuang, S W Lee, C Y Wu, H Z Yeh, T Y Lee
BACKGROUND: Renal dysfunction remains an issue in tenofovir disoproxil fumarate (TDF) for chronic hepatitis B (CHB) patients. AIM: To evaluate renal safety of TDF according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. METHODS: We retrospectively recruited CHB patients who received either TDF or entecavir (ETV) monotherapy from January 2008 to August 2015. After excluding confounding conditions, 253 patients who received TDF were randomly matched 1:2 with 506 patients who received ETV through the propensity scores, which consisted of age, gender, cirrhosis, chronic kidney disease (CKD) and estimated glomerular filtration rate (eGFR)...
April 25, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29685343/weekly-versus-3-weekly-cabazitaxel-for-the-treatment-of-castration-resistant-prostate-cancer-a-randomised-phase-ii-trial-concab
#8
Jeffrey Yachnin, Bjørnar Gilje, Kristian Thon, Hemming Johansson, Yvonne Brandberg, Theocharis Panaretakis, Anders Ullén
AIM: Patients treated with cabazitaxel for metastatic castration-resistant prostate cancer (mCRPC) may experience dose delays and reductions or terminate treatment because of toxicity. A lower and more frequent dose of cabazitaxel could improve dose intensity. PATIENTS AND METHODS: This prospective, multi-center, phase II study randomly assigned 101 patients to Arm A, cabazitaxel Q3W, 25 mg/m2 or Arm B, Q1W, 10 mg/m2 5 of 6 weeks. The primary end-point was dose intensity, and we hypothesised that the experimental arm (Arm B) would result in a 20% absolute increase in the relative cumulative dose by week 18...
April 20, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29669479/long-term-use-of-hydraulic-artificial-urethral-sphincters-in-nine-dogs-from-new-zealand-with-urethral-sphincter-mechanism-incompetence
#9
K R S Morgan, H R Milner, A Tikekar, H L Smith, A R Coomer
AIMS: To report on the long-term outcomes of hydraulic artificial urethral sphincter (HAUS) placement for the correction of urethral sphincter mechanism incompetence (USMI) in New Zealand dogs. METHODS: Retrospective data were obtained from cases of dogs which had a HAUS placed after failed medical and/or surgical management of USMI between August 2012 and November 2016. Owner assessment of urinary incontinence was evaluated by an online survey in May 2017 using a visual analogue scale (0 being normal, 100 being severely affected) for the frequency, volume and severity of any straining to urinate, immediately prior to the placement of the HAUS and at the time of the survey...
April 18, 2018: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/29643881/urinary-tract-infections-in-the-geriatric-patients
#10
Yesim Alpay, Nevil Aykin, Pinar Korkmaz, Hakki Mustafa Gulduren, Figen Cevik Caglan
Objective: Urinary tract infections (UTI) are the second most common infection in geriatric population. This study investigated clinical findings, diagnostic approaches, complicating factors, prognosis, causative microorganisms and antimicrobial susceptibility in geriatric patients diagnosed with UTI. Methods: A total of 140 hospitalised patients with UTIs were evaluated within three years between January 2011-January 2015 at the Eskisehir Yunus Emre State Hospital...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29616147/dynamics-of-paediatric-urogenital-schistosome-infection-morbidity-and-treatment-a-longitudinal-study-among-preschool-children-in-zimbabwe
#11
Derick Nii Mensah Osakunor, Takafira Mduluza, Nicholas Midzi, Margo Chase-Topping, Masceline Jenipher Mutsaka-Makuvaza, Theresa Chimponda, Enwono Eyoh, Tariro Mduluza, Lorraine Tsitsi Pfavayi, Welcome Mkululi Wami, Seth Appiah Amanfo, Janice Murray, Clement Tshuma, Mark Edward John Woolhouse, Francisca Mutapi
Background: Recent research has shown that in schistosome-endemic areas preschool-aged children (PSAC), that is, ≤5 years, are at risk of infection. However, there exists a knowledge gap on the dynamics of infection and morbidity in this age group. In this study, we determined the incidence and dynamics of the first urogenital schistosome infections, morbidity and treatment in PSAC. Methods: Children (6 months to 5 years) were recruited and followed up for 12 months...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29606255/recent-advances-in-the-physiopathology-of-iga-nephropathy
#12
Renato C Monteiro
Immunoglobulin A nephropathy or Berger's disease is the most common type of primary glomerulonephritis, which is characterized by IgA1-containing immune-deposits in the glomerular mesangium. Microscopic haematuria and proteinuria are the most common presentations. Mesangial cell proliferation with IgA deposition is found on renal biopsy. Mechanims of the disease implicate at least four key molecules have been implicated in immune complex formation: galactose-deficient IgA1, autoantibodies anti-galactose-deficient-IgA1, soluble CD89 (Fc receptor for IgA) and the CD71 mesangial IgA receptor (transferrin receptor)...
April 2018: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29588281/when-a-transfusion-in-an-emergency-service-is-not-really-urgent-hyperhaemolysis-syndrome-in-a-child-with-sickle-cell-disease
#13
Sara Chinchilla Langeber, Marta Pilar Osuna Marco, María Benedit, Áurea Cervera Bravo
A 13-month-old boy with sickle cell disease (SCD) from Equatorial Guinea, who had recently arrived in Spain, presented with fever. He had suffered from malaria and had received a blood transfusion. Following physical examination and complementary tests, intravenous antibiotics and a red blood cell (RBC) transfusion were administered. Soon after a second transfusion 5 days later, the haemoglobin level fell below pretransfusion levels, together with reticulocytopenia, and haematuria-the so-called hyperhaemolysis syndrome-requiring intensive care and treatment with intravenous immunoglobulins and corticosteroids, with resolution of the complication...
March 27, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29582127/prostatic-artery-embolization-pae-for-benign-prostatic-hyperplasia-bph-with-haematuria-in-the-absence-of-an-upper-urinary-tract-pathology
#14
Charles R Tapping, Andrew Macdonald, Mo Hadi, Chloe Mortensen, Jeremy Crew, Andrew Protheroe, Mark W Little, Phil Boardman
PURPOSE: To assess the effectiveness of prostate artery embolization (PAE) in the control of haematuria and in patients with benign prostatic hyperplasia (BPH) and normal upper urinary tracts. SUBJECTS/PATIENTS: Twelve consecutive patients with haematuria were included in the prospective study. All patients had prior imaging and cystoscopy to exclude other causes of haematuria. Patients prostate arteries were embolized with particles (200-500 μm), and they were followed up at 3, 12 and 18 months following the procedure...
March 26, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29577510/successful-treatment-with-steroid-and-cyclosporine-a-in-a-patient-with-immunoglobulin-a-proliferative-glomerulonephritis-with-monoclonal-immunoglobulin-deposits
#15
Keisuke Sato, Shiho Makabe, Yuko Iwabuchi, Kaori Kojima, Masayo Sato, Hiroshi Kataoka, Takahito Moriyama, Sekiko Taneda, Ken Tsuchiya, Kosaku Nitta, Toshio Mochizuki
We report a case of glomerulonephritis with monoclonal immunoglobulin (Ig) A deposits as a form of monoclonal gammopathy of renal significance (MGRS) caused by monoclonal immunoglobulins without blood disorders in a 41-year-old woman. She developed lower leg oedema and was hospitalized because of nephrotic syndrome. Serum and urine were negative for M protein, and the free light chain κ/λ ratio was within the normal range. Renal histopathological findings included mesangial proliferation, endocapillary cell proliferation, and a double-contour appearance of the capillary walls...
March 25, 2018: Nephrology
https://www.readbyqxmd.com/read/29572365/a-rare-presentation-of-haematuria-hip-prosthesis-in-the-bladder
#16
Yih Chyn Phan, Nnaemeka Eli, Praveen Pillai, Jonathan O'Dair
An 80-year-old woman presented to our department with visible haematuria and stage II acute kidney injury (AKI). She had stage IIB cervical cancer, for which she received chemotherapy and external beam radiotherapy in 2003. Four years later, she had a left dynamic hip screw for an extracapsular neck of femur fracture following a fall. In 2010, she underwent a right total hip replacement owing to osteoarthritis, and it was subsequently revised in 2012 owing to a right acetabular component failure. In this admission, her AKI improved with intravenous fluid administration and her haematuria settled following catheterisation with a three-way catheter and bladder irrigation with saline...
March 22, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29563127/renal-injury-in-a-patient-with-lumbar-scoliosis
#17
Harjoat Riyat, Richard Jones, Debashis Sarkar, Richard Stephenson
Kidney laceration following blunt trauma is responsible for up to 3% of trauma cases. The risk factors associated with renal injury are attributed to the risks of mechanical injury. However, anatomical variations that may accelerate the insult of injury are poorly documented. This case report describes a 25-year-old with degenerative lumbar scoliosis who presented with flank pain and visible haematuria following a low-impact injury. The patient had a grade IV renal injury. The curvature of the spine, shown on CT imaging, revealed a reduced retroperitoneal space around the left kidney...
March 21, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29552340/a-retrospective-analysis-of-the-utility-and-safety-of-kidney-transplant-biopsies-by-nephrology-trainees-and-consultants
#18
Michael E Reschen, Andrea Mazzella, Edward Sharples
Background and aims: Dysfunction of a kidney transplant often requires histological sampling by percutaneous ultrasound-guided core needle biopsy. Transplant biopsy is more specialized than native kidney biopsy, the indications and complications are less well defined and in England are performed mainly by nephrologists. The aims of the study were to evaluate the adequacy and complication rate in living and deceased donor recipients according to training status of the nephrologist, assess the accuracy of physicians in predicting rejection, the threshold creatinine rise for biopsy, and the change in drug management post-biopsy...
April 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29545130/-renal-involvement-of-cryoglobulinemia
#19
Alexandre Karras
Cryoglobulins are immunoglobulins that undergo reversible precipitation at low temperatures. They can induce systemic vasculitis, characterized by purpuric cutaneous lesions, arthritis, peripheral neuropathy, hypocomplementemia and glomerular disease. Renal pathology reveals membranoproliferative glomerulonephritis, with particularly intense mesangial cell proliferation and infiltration by macrophages, associated with intracapillary thrombi. This renal disease presents as a nephritic syndrome, with heavy proteinuria, haematuria severe hypertension and rapidly progressive kidney failure that can lead to end-stage renal disease...
April 2018: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29543050/the-changing-practice-of-transurethral-resection-of-the-prostate
#20
M J Young, M Elmussareh, T Morrison, J R Wilson
Introduction Transurethral resection of the prostate (TURP) is considered the gold standard surgical treatment for lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia. The number of TURPs performed has declined significantly over the last three decades owing to pharmaceutical therapy. TURP data from a single institution for the years 1990, 2000 and 2010 were compared to assess the difference in performance. Methods A retrospective analysis was undertaken of all patients who underwent TURP between January and December 2010...
March 15, 2018: Annals of the Royal College of Surgeons of England
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