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Mucosa thickness

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https://www.readbyqxmd.com/read/28090006/expression-of-apical-junction-complex-proteins-in-colorectal-mucosa-of-miniature-dachshunds-with-inflammatory-colorectal-polyps
#1
Nozomu Yokoyama, Hiroshi Ohta, Yumiko Kagawa, Rommaneeya Leela-Arporn, Angkhana Dermlim, Khoirun Nisa, Tomoya Morita, Tatsuyuki Osuga, Noboru Sasaki, Keitaro Morishita, Kensuke Nakamura, Mitsuyoshi Takiguchi
We examine the expression of tight junction and adherence junction proteins in the colorectal mucosa of miniature dachshunds (MDs) with inflammatory colorectal polyps (ICRPs). Colorectal mucosa samples were endoscopically obtained from 8 MDs with ICRPs and 8 control dogs for immunoblotting. Paraffin-embedded tissues of surgically resected inflamed lesions from another 5 MDs with ICRPs and full-thickness colorectal specimens from 5 healthy beagles were obtained for immunohistochemistry. The expression patterns of claudin-1, -2, -3, -4, -5, -7 and -8, E-cadherin and β-catenin were analyzed in the non-inflamed mucosa and inflamed mucosa of ICRPs and colorectal mucosa of control dogs by immunoblotting...
January 16, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28089715/ameliorating-effects-of-herbal-formula-hemomine-on-experimental-subacute-hemorrhagic-anemia-in-rats
#2
Sae Kwang Ku, Hyemee Kim, Joo Wan Kim, Ki Sung Kang, Hae-Jeung Lee
ETHNOPHARMACOLOGICAL RELEVANCE: Hemomine (HM) is an herbal mixture consisting of 5 varieties of the hematopoietic herbal extracts (Angelica gigas Nakai, Cnidium officinale Makino, Paeonia lactiflora Pall., Rehmannia glutinosa Liboschitz ex Stueudel, Glycyrrhiza uralensis Fischer). AIM OF THE STUDY: Anemia has been treated with iron supplements, whereas it could cause adverse side effects such as digestive discomfort. In the present study, HM was applied to SHA rats to test for several activities so as to verify its therapeutic potentials on anemia and digestive discomfort...
January 9, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28079827/differentiating-malignant-from-benign-gastric-mucosal-lesions-with-quantitative-analysis-in-dual-energy-spectral-computed-tomography-initial-experience
#3
Xiaoyan Meng, Cheng Ni, Yaqi Shen, Xuemei Hu, Xiao Chen, Zhen Li, Daoyu Hu
To investigate the value of quantitative analysis in dual energy spectral computed tomography (DESCT) for differentiating malignant gastric mucosal lesions from benign gastric mucosal lesions (including gastric inflammation [GI] and normal gastric mucosa [NGM]). This study was approved by the ethics committee, and all patients provided written informed consent. A total of 161 consecutive patients (63 with gastric cancer [GC], 48 with GI, and 50 with NGM) who underwent dual-phase contrast enhanced DESCT scans in the arterial phase (AP) and portal venous phase (PVP) were included in this study...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28076513/serum-concentration-of-vascular-endothelial-growth-factor-and-depth-of-trophoblastic-invasion-in-ampullary-ectopic-pregnancy
#4
Fábio Roberto Cabar, Décio Roberto Kamio Teshima, Pedro Paulo Pereira, Leila Antonangelo, Regina Schultz, Rossana Pulcineli Francisco
OBJECTIVE: To evaluate the association between the depth of trophoblastic infiltration and serum vascular endothelial growth factorconcentration in patients with an ampullary pregnancy. METHODS: This prospective cross-sectionalstudy involved 34 patients with an ampullary ectopic pregnancy who underwent salpingectomy between 2012 and 2013. Maternal serum vascular endothelial growth factor concentrations were measured using Luminex technology. Trophoblastic invasion was classified histologically as follows: stage I, limited to the tubal mucosa; stage II, reaching the muscle layer; and stage III,involving the full thickness...
December 1, 2016: Clinics
https://www.readbyqxmd.com/read/28053617/characterization-the-response-of-korl-icr-mice-to-loperamide-induced-constipation
#5
Ji Eun Kim, Woo Bin Yun, Ji Eun Sung, Hyun Ah Lee, Jun Young Choi, Yeon Shik Choi, Young Suk Jung, Kil Soo Kim, Dae Youn Hwang
Animal models of constipation induced with drugs and diet have been widely employed to investigate therapeutic effects and the action mechanism of drugs against this disease. ICR mice were selected to produce this disease model through oral administration of loperamide (Lop), even though SD rats are commonly utilized in studies of constipation. To compare the responses of ICR mice obtained from three different sources to constipation inducers, alterations in stool number, histopathological structure, mucin secretion and opioid-receptor downstream signaling pathway were measured in Korl:ICR (Korea FDA source), A:ICR (USA source) and B:ICR (Japan source) injected with low and high concentrations of Lop (LoLop and HiLop)...
December 2016: Laboratory Animal Research
https://www.readbyqxmd.com/read/28050414/radiological-study-of-maxillary-sinus-using-cbct-relationship-between-mucosal-thickening-and-common-anatomic-variants-in-chronic-rhinosinusitis
#6
Marco Capelli, Patrizia Gatti
INTRODUCTION: Inflammatory diseases of the maxillary sinus favour the thickening of the sinus mucosa. Therefore, it might be possible to establish a radiological, pathological threshold of mucosal thickening. Furthermore, there is an association between common anatomic variants of the nose and maxillary mucosal thickening. AIM: To define the pathological thickening of maxillary sinus mucosa and its association with the presence of common anatomic variants (concha bullosa, Haller's cell and accessory maxillary ostium)...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28048594/su-f-t-360-dosimetric-impacts-on-the-mucosa-and-bone-in-radiotherapy-with-unflattened-photon-beams
#7
J Chow, A Owrangi
PURPOSE: This study investigated the dosimetric impacts on the mucosa and bone when using the unflattened photon beams in radiotherapy. Dose calculations were carried out by Monte Carlo simulation. METHODS: Heterogeneous phantoms containing water (soft tissue and mucosa), air and bone, with mucosa thicknesses varying from 0.5 - 3 mm were irradiated by the 6 MV unflattened and flattened photon beams (field size = 10 × 10 cm(2) ), produced by a Varian TrueBEAM linear accelerator...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28029282/assessment-of-eosinophil-peroxidase-as-a-potential-diagnostic-and-prognostic-marker-in-dogs-with-inflammatory-bowel-disease
#8
Idil Bastan, Nicholas A Robinson, Xiao Na Ge, Aaron K Rendahl, Savita P Rao, Robert J Washabau, P Sriramarao
OBJECTIVE To evaluate a method for identifying intact and degranulated eosinophils in the small intestine of dogs with inflammatory bowel disease (IBD) by use of a monoclonal antibody (mAb) against eosinophil peroxidase (EPX). ANIMALS 11 untreated dogs with IBD, 5 dogs with IBD treated with prednisolone, and 8 control dogs with no clinical evidence of gastrointestinal tract disease and no immunosuppressive treatment. PROCEDURES 4-μm-thick sections of paraffin-embedded tissues from necropsy specimens were immunostained with EPX mAb...
January 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/27992776/differential-response-of-olfactory-sensory-neuron-populations-to-copper-ion-exposure-in-zebrafish
#9
Maurizio Lazzari, Simone Bettini, Liliana Milani, Maria Gabriella Maurizii, Valeria Franceschini
The peripheral olfactory system of fish is in direct contact with the external aqueous environment, so dissolved contaminants can easily impair sensory functions and cause neurobehavioral injuries. The olfactory epithelium of fish is arranged in lamellae forming a rosette in the olfactory cavity and contains three main types of olfactory sensory neurons (OSNs): ciliated (cOSNs) and microvillous olfactory sensory neurons (mOSNs), common to all vertebrates, and a third minor group of olfactory neurons, crypt cells, absent in tetrapods...
December 14, 2016: Aquatic Toxicology
https://www.readbyqxmd.com/read/27983903/analyses-and-classification-of-complexities-in-rhinoplasties-based-on-factors-increasing-the-difficulty-and-their-appropriate-reconstruction
#10
Aret Çerçi Özkan, Ahmet Mert Bilgili, Erdem Güven
OBJECTIVES: This study aims to classify the factors that make rhinoplasty difficult and appropriate reconstruction of it. PATIENTS AND METHODS: We retrospectively evaluated the records of 103 patients who underwent rhinoplasty at our private clinic between April 2002 and December 2014. The most important reagent affecting the degree of difficulty in our study was the adhesion of the bone and cartilaginous structures to the skin and mucosa, as an outcome of on previous operations...
November 2016: Kulak Burun Boğaz Ihtisas Dergisi: KBB, Journal of Ear, Nose, and Throat
https://www.readbyqxmd.com/read/27977828/modified-lip-repositioning-with-esthetic-crown-lengthening-a-combined-approach-to-treating-excessive-gingival-display
#11
Isis M Sánchez, Sadja Gaud-Quintana, Jacob K Stern
Lip repositioning surgery to address excessive gingival display induced by different etiologies has received major attention recently. Several techniques and variations have been reported, including myotomy or repositioning of the levator labii superioris muscle, Le Fort impaction, maxillary gingivectomies, botulinum toxin injections, and lip stabilization. This study reports a case of excessive gingival display treated by a modified combined approach. A 25-year-old woman with a 4- to 8-mm gingival display when smiling caused by a combination of short clinical crowns induced by an altered passive eruption and hypermobility of the upper lip underwent a staged esthetic crown-lengthening procedure followed by a modified lip repositioning technique...
January 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/27915337/quercetin-assists-fluconazole-to-inhibit-biofilm-formations-of-fluconazole-resistant-candida-albicans-in-in-vitro-and-in-vivo-antifungal-managements-of-vulvovaginal-candidiasis
#12
Mei Gao, Hui Wang, LiJuan Zhu
BACKGROUND: Vulvovaginal candidiasis (VVC) is a common gynecological disease. Candida albicans is believed to be mainly implicated in VVC occurrence, the biofilm of which is one of the virulence factors responsible for resistance to traditional antifungal agents especially to fluconazole (FCZ). Quercetin (QCT) is a dietary flavonoid and has been demonstrated to be antifungal against C. albicans biofilm. METHODS: 17 C. albicans isolates including 15 clinical ones isolated from VVC patients were employed to investigate the effects of QCT and/or FCZ on the inhibition of C...
2016: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/27899200/-mucoadhesive-buccal-films-of-tramadol-for-effective-pain-management
#13
Xiao-Qin Li, Zhao-Ming Ye, Jian-Bing Wang, Cai-Rong Fan, Ai-Wu Pan, Cong Li, Ren-Bing Zhang
BACKGROUND AND OBJECTIVES: Tramadol hydrochloride is a centrally-acting synthetic opioid analgesic binding to specific opioid receptors. It is used in the management of chronic pain and is recommended as first line drug in the treatment of postoperative or orthopedic injury induced acute pain. The present work is designed to prepare and evaluate mucoadhesive buccal film of tramadol hydrochloride as a novel form of prolonged analgesia for patients with orthopedic injuries. METHODS: Buccal films of tramadol hydrochloride were prepared by solvent casting method...
November 26, 2016: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/27898453/resolution-of-rectal-prolapse-by-vaginal-reconstruction
#14
Hemikaa Devakumar, Neeraja Chandrasekaran, Alexandriah Alas, Laura Martin, G Willy Davila, Eric Hurtado
BACKGROUND: Rectal prolapse is a disorder of the pelvic floor in which the layers of the rectal mucosa protrude outward through the anus. Surgical repair is the mainstay of treatment. Options include intra-abdominal procedures such as rectopexy and perineal procedures such as the Delorme and Altemeier perineal rectosigmoidectomy. Rectal and vaginal prolapse can often coexist. However, to our knowledge, there are no reported cases of rectal prolapse resolved by the repair of a compressive enterocele abutting the anterior rectal wall through a vaginal approach alone...
January 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27885166/the-role-of-interleukin-33-in-chronic-rhinosinusitis
#15
Dong-Kyu Kim, Hong Ryul Jin, Kyoung Mi Eun, Ji-Hun Mo, Seong H Cho, Sohee Oh, David Cho, Dae Woo Kim
RATIONALE: Interleukin (IL)-33, a new member of the IL-1 family, is constitutively expressed in epithelial tissues and lymphoid organs and plays an important role in the pathogenesis of allergic disease. However, the role of IL-33 in chronic rhinosinusitis with nasal polyps (CRSwNP) remains unclear. OBJECTIVE: To investigate the role of IL-33 in the pathophysiology of CRSwNP. METHODS: We investigated IL-33 expression and its cellular origins in the nasal polyps (NPs) of human subjects by immunohistochemistry (IHC), quantitative reverse transcription PCR (qRT-PCR), and multiplex cytokine assays...
November 24, 2016: Thorax
https://www.readbyqxmd.com/read/27878464/impact-of-abutment-material-on-peri-implant-soft-tissue-color-an-in-vitro-study
#16
Sala Leticia, Bascones-Martínez Antonio, Carrillo-de-Albornoz Ana
OBJECTIVES: The objectives of the present study is to determine the differences in peri-implant soft tissue color with the utilization of titanium, titanium gold-plated, white zirconia, Vita Classical (VC) A4-shaded zirconia, and fluorescent white zirconia abutments and to establish the influence of gingival thickness on the resulting color. METHODS: Four implants were contralaterally inserted in 19 fresh pig mandibles, and the color of the peri-implant mucosa with the different abutments was spectrophotometrically measured at 1-, 2-, and 3-mm height from the margin...
November 22, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27873018/soft-tissue-augmentation-around-osseointegrated-and-uncovered-dental-implants-a-systematic-review
#17
REVIEW
Renzo G Bassetti, Alexandra Stähli, Mario A Bassetti, Anton Sculean
OBJECTIVES: The aim was to compile the current knowledge about the efficacy of different soft tissue correction methods around osseointegrated, already uncovered and/or loaded (OU/L) implants with insufficient soft tissue conditions. Procedures to increase peri-implant keratinized mucosa (KM) width and/or soft tissue volume were considered. MATERIALS AND METHODS: Screening of two databases: MEDLINE (PubMed) and EMBASE (OVID), and manual search of articles were performed...
January 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27872534/use-of-combined-pmmc-and-nasolabial-flap-for-reconstruction-of-full-thickness-cheek-defect-involving-lip-commisure
#18
Mahendra I Katre, Sunil Deshmukh, Pramod Dhanajkar
Head neck cancer constitute significant cancer burden and among it carcinoma of oral cavity involving buccal mucosa is most common entity in India. Very often it involves lip commisure. Radical surgery along with radiotherapy still remains treatment of choice. Reconstruction of composite defect of oral cavity fallowing ablative surgery remains difficult task. Reconstruction of lip commisure defect after primary tumor excision is still a big challenge. Micro vascular technique primary repair is main modality of treatment which needs great surgical expertise in plastic surgery which is not possible in every institution...
December 2016: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27863547/identification-of-histamine-receptors-in-the-canine-gastrointestinal-tract
#19
Alyssa Sullivant, Andrew Mackin, Todd Pharr, Jim Cooley, Robert Wills, Todd Archer
The important role of histamine in chronic gastrointestinal diseases has been increasingly recognized over the last two decades in human medicine. Histamine is released following mast cell activation and exerts its action through binding to four different histamine receptors (H1, H2, H3, and H4). Histamine receptors are dispersed throughout the body, and each different receptor mediates a unique response. Documentation of the presence and type of histamine receptors in the differing sections of the canine gastrointestinal tract will provide additional research opportunities to further explore the role of histamine and its receptors in chronic canine enteropathies, as well as potential therapeutic options...
December 2016: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/27859294/tgf-%C3%AE-antagonist-attenuates-fibrosis-but-not-luminal-narrowing-in-experimental-tracheal-stenosis
#20
Juan L Antón-Pacheco, Alicia Usategui, Iván Martínez, Carmen M García-Herrero, Antonio P Gamez, Montserrat Grau, Ana M Martínez, José L Rodríguez-Peralto, José L Pablos
OBJECTIVE: Acquired tracheal stenosis (ATS) is an unusual disease often secondary to prolonged mechanical trauma. Acquired tracheal stenosis pathogenesis involves inflammation and subsequent fibrosis with narrowing of the tracheal lumen. Transforming growth factor-β1 (TGF-β) represents a pivotal factor in most fibrotic processes, and therefore a potential target in this context. The aim of this study is to analyze the role of TGF-β as a target for anti-fibrotic interventions in tracheal stenosis...
November 16, 2016: Laryngoscope
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