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https://www.readbyqxmd.com/read/29786675/combined-effectiveness-of-honey-and-immunonutrition-on-bacterial-translocation-secondary-to-obstructive-jaundice-in-rats-experimental-study
#1
Serhat Oguz, Omer Salt, Abdil C Ibis, Saban Gurcan, Dogan Albayrak, Tulin Yalta, Tamer Sagiroglu, Cengiz Erenoglu
BACKGROUND Obstructive jaundice is a serious, life-threatening condition that can lead to death as a result of sepsis and multiorgan failure due to bacterial translocation. Treatment should be started as soon as possible after diagnosis. MATERIAL AND METHODS Forty 24-week-old male Sprague Dawley rats, with an average weight of 250 g to 300 g, were included in this study. The rats were randomly placed into five groups, each group consisted of eight rats. The sham group underwent only common bile duct (CBD) dissection and no ligation was performed...
May 22, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29770154/effects-of-platycodin-d-on-reflux-esophagitis-due-to-modulation-of-antioxidant-defense-systems
#2
Su-Yeon Cho, Chang-Hyun Song, Ji-Eun Lee, Seong Hun Choi, Sae-Kwang Ku, Soo-Jin Park
Aims: The effects of platycodin D (PD) pretreatment were examined in reflux esophagitis (RE) induced rats. Methods: Sham, control, and omeprazole (OMP) group were pretreated with distilled water or OMP as a reference, respectively, and PD pretreated groups were given 3 different PD doses once a day for 7 days. One hour after last pretreatment, RE was induced by ligation of the forestomach and pylorus. At 8 h after operation, all animals were sacrificed. Results: PD showed significant dose-dependent reduction of gastric secretion, myeloperoxidase activity, and RE lesion areas of esophagus and stomach mucosa...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29768644/endoscopic-mucosa-sparing-lateral-dissection-for-treatment-of-gastric-submucosal-tumors-a-prospective-cohort-study
#3
Yue Li, Qiang Zhang, Chaojun Zhu, Yuchen Luo, Zelong Han, Haitao Qing, Jianqun Cai, Ling Li, Ying Huang, Side Liu
BACKGROUND:  In our previous work, we developed a modified method for the removal of gastric submucosal tumors (SMTs), called endoscopic mucosa-sparing lateral dissection (EMSLD). This prospective study aimed to evaluate the efficacy and postoperative outcomes of EMSLD. METHODS:  We prospectively enrolled 25 consecutive patients with gastric SMTs, who received EMSLD treatment. Clinicopathological characteristics and operation-related outcomes were analyzed. RESULTS:  The mean age of patients was 49...
May 16, 2018: Endoscopy
https://www.readbyqxmd.com/read/29766790/malt-lymphoma-stress-ulcer-and-cholinergic-nerves-from-the-viewpoint-of-bilateral-and-unilateral-truncal-vagotomy-and-substance-p
#4
Yosuke Kodama, Kazuki Sasaki, Futa Murasato, Anders Øverby, Shinichi Takahashi, Somay Y Murayama, Hidenori Matsui, Masahiko Nakamura
BACKGROUND: Vagal nerve plays an important role in the stomach function. The cholinergic nerves are the most abundantly distributed nerves in the gastric tissue. It has recently been reported that the vagal nerve is significantly related to both gastric cancer development and progression. However, its relation to the mesenchymal tumor, including MALT lymphoma, is not known. In this study, we investigated the effect of unilateral truncal vagotomy on gastric MALT lymphoma development by using Helicobacter heilmannii-infected mouse model as well as that of bilateral truncal vagotomy on stress-induced ulcer formation...
May 15, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29765272/approach-to-reconstruction-of-cheek-defects
#5
REVIEW
Berkay Başağaoğlu, Mohin Bhadkamkar, Pierce Hollier, Edward Reece
The cheek is the largest facial unit with a prominent position on the face. Trauma, burns, and the resection of skin cancers constitute common sources of injury, potentially resulting in defects that, through natural healing, produce noticeable scarring. Surgical repair focuses on the reformation of three-dimensional geometries, proper establishment of symmetry, and the minimization of color and texture discrepancies to the surrounding. Defects located in this region may extend to the orbital, nasal, or buccal units and cause unique structural and functional disturbances...
May 2018: Seminars in Plastic Surgery
https://www.readbyqxmd.com/read/29755298/addressing-female-genital-mutilation-cutting-fgm-c-in-the-era-of-clitoral-reconstruction-plastic-surgery
#6
REVIEW
Hannes Sigurjonsson, Malin Jordal
Purpose of the Review: The aim of this review is to give an overview of the recent evidence on clitoral reconstruction and other relevant reconstructive plastic surgery measures after female genital mutilation/cutting (FGM/C). Recent Findings: Recent publications present refinements and modifications of the surgical technique of clitoral reconstruction along with reconstruction of the labia majora and clitoral hood. Novel approaches with reposition of the clitoral nerve, anchoring of the labia majora, fat grafting, and full thickness mucosa grafts have been introduced...
2018: Current Sexual Health Reports
https://www.readbyqxmd.com/read/29754035/the-elusive-small-bowel-adenocarcinoma-in-the-terminal-ileum-a-case-report
#7
Joyce Lok Gee Ma, Paul Norman Strauss
INTRODUCTION: Small bowel malignancies are rare and often present with non-specific symptoms. Because of this, diagnosis of small bowel malignancies is often missed. PRESENTATION OF CASE: 71-year-old male presented with a four-week history of right iliac fossa pain and loss of weight. Laboratory tests showed a raised C-reactive protein, but all other pathology results and tumour-associated antigens were normal. Computed tomography (CT) of the abdomen demonstrated an inflammatory mass extending laterally into the pelvic wall...
April 27, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29740349/severe-burn-induced-intestinal-epithelial-barrier-dysfunction-is-associated-with-endoplasmic-reticulum-stress-and-autophagy-in-mice
#8
Yalan Huang, Yanhai Feng, Yu Wang, Pei Wang, Fengjun Wang, Hui Ren
The disruption of intestinal barrier plays a vital role in the pathophysiological changes after severe burn injury, however, the underlying mechanisms are poorly understood. Severe burn causes the disruption of intestinal tight junction (TJ) barrier. Previous studies have shown that endoplasmic reticulum (ER) stress and autophagy are closely associated with the impairment of intestinal mucosa. Thus, we hypothesize that ER stress and autophagy are likely involved in burn injury-induced intestinal epithelial barrier dysfunction...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29733104/fractional-co-2-laser-treatment-for-vaginal-laxity-a-preclinical-study
#9
Tae-Rin Kwon, Jong Hwan Kim, Joon Seok, Jae Min Kim, Dong-Ho Bak, Mi-Ji Choi, Seok Kyun Mun, Chan Woong Kim, Seungwon Ahn, Beom Joon Kim
BACKGROUND AND OBJECTIVE: Various studies have investigated treatment for vaginal laxity with microablative fractional carbon dioxide CO2 laser in humans; however, this treatment has not yet been studied in an animal model. Herein, we evaluate the therapeutic effects of fractional CO2 laser for tissue remodeling of vaginal mucosa using a porcine model, with the aim of improving vaginal laxity. STUDY DESIGN/MATERIALS AND METHODS: The fractional CO2 laser enables minimally invasive and non-incisional procedures...
May 7, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29729031/risk-factors-of-cancer-occurrence-after-surgery-of-oral-intraepithelial-neoplasia-a-long-term-retrospective-study
#10
Stanislas Ballivet de Régloix, Nathalie Badois, Celine Bernardeschi, Thomas Jouffroy, Caroline Hofmann
OBJECTIVE: Oral intraepithelial neoplasia (OIN) is a premalignant lesion of oral mucosa graded I through III according to the importance of atypic cells and the thickness of the dysplastic layers. The aim of this study was to evaluate the long-term clinical course of OIN lesions and identify predictive factors of outcomes. METHODS: The clinical, surgical, and follow-up data of the patients consecutively treated for OIN by primary surgical removal in a referral anti-cancer center from November 1998 to March 2009 were retrospectively analyzed...
May 4, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29723632/phenotypic-markers-of-oral-keratinocytes-seeded-on-two-distinct-3d-oral-mucosa-models
#11
Fernanda G Basso, Taisa N Pansani, Cyntia L Marcelo, Carlos Alberto de Souza Costa, Josimeri Hebling, Stephen E Feinberg
This study validates the use of a full-thickness oral mucosa model for in vitro studies with a collagen type I matrix, by comparison of this model with two other 3D oral mucosa models: human-sourced and porcine acellular dermal matrices (AlloDerm®/Strattice®, respectively). For the collagen matrix model, gingival fibroblasts were seeded either onto the dermal side of the AlloDerm® and Strattice® matrices or within the collagen matrices in complete culture medium (DMEM). For all scaffolds, DMEM was replaced every 24 h up to 72 h...
April 30, 2018: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/29707180/accuracy-of-guided-surgery-via-stereolithographic-mucosa-supported-surgical-guide-in-implant-surgery-for-edentulous-patient-a-systematic-review
#12
REVIEW
Cheongbeom Seo, Gintaras Juodzbalys
Objectives: The purpose of the present study is to systematically review the accuracy of implant placement with mucosa-supported stereolithographic surgical guide and to find out what factors can influence the accuracy. Material and Methods: An electronic literature search was performed through the MEDLINE (PubMed) and EMBASE databases. The articles are including human studies published in English from October 2008 to October, 2017. From the examination of selected articles, deviations between virtual planning and actual implant placement were analysed regarding the global apical, global coronal, and angulation position...
January 2018: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/29697667/-features-of-the-pathogenesis-of-the-placenta-growing-in-the-scar-after-cesarean-section
#13
I V Barinova, N I Kondrikov, I N Voloshchuk, M A Chechneva, N A Shchukina, V A Petrukhin
OBJECTIVE: to investigate the structural and pathogenetic features of pathological placental attachment in the scar after cesarean section. MATERIAL AND METHODS: The investigators explored 12 uteri; 11 of which were removed with placentas at 9 to 38 weeks' gestation (one in the first trimester, three at 18-22 weeks, two at 32-35 weeks, and five at 37-38 weeks); one uterus was removed after an artificial abortion at 12 weeks' gestation in the scar, as well as the scars excised in the first trimester in non-developing (n=4) and progressive (n=2) pregnancies...
2018: Arkhiv Patologii
https://www.readbyqxmd.com/read/29689410/optimized-phospholipid-based-nanoparticles-for-inner-ear-drug-delivery-and-therapy
#14
Keum-Jin Yang, Jihwan Son, So Young Jung, Gawon Yi, Jihye Yoo, Dong-Kee Kim, Heebeom Koo
To develop efficient carriers for inner ear drug delivery, we prepared four kinds of phospholipid-based nanoparticles: neutral, anionic, cationic, and cationic-PEG (polyethyleneglycol) particles. PEG was used to maintain long-term particle circulation in the perilymph, avoiding non-specific binding of particles to proteins. All four nanoparticles were about 200 nm in diameter, and their zeta potentials were -4.32, -26.0, +25.8, and -0.28, respectively, for neutral, anionic, cationic, and cationic-PEG nanoparticles...
April 16, 2018: Biomaterials
https://www.readbyqxmd.com/read/29686919/grinspan-s-syndrome-a-rare-case-with-malignant-transformation
#15
Numan Kökten, Lokman Uzun, Ayşe Serap Karadağ, Tülay Zenginkinet, M Tayyar Kalcıoğlu
Aim: Oral lichen planus (OLP) is one of the common chronic inflammatory, noninfectious, and precancerous oral mucosal diseases that affect the stratified squamous epithelium in adults. Grinspan et al. reported an association of OLP with diabetes mellitus and vascular hypertension and called that Grinspan's syndrome in 1966. We aim to present a case of Grinspan's syndrome with malignant transformation. Case Presentation: A 60-year-old man who presented with a ten-year history of OLP diagnosed clinically and histologically was referred to our otolaryngology department with a painless swallowing in the left buccal mucosa for 3 months...
2018: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/29679780/diagnostic-accuracy-of-mdct-in-differentiating-gallbladder-cancer-from-acute-and-xanthogranulomatous-cholecystitis
#16
Ashish P Wasnik, Mathew S Davenport, Ravi K Kaza, William J Weadock, Aaron Udager, Nahid Keshavarzi, Bin Nan, Katherine E Maturen
OBJECTIVE: To determine the diagnostic accuracy of multi-detector CT (MDCT) for differentiating gallbladder cancer from acute and xanthogranulomatous cholecystitis using previously described imaging features. METHODS: In this IRB approved HIPAA-compliant retrospective cohort study, contrast-enhanced MDCT of histologically confirmed acute cholecystitis (n = 17), xanthogranulomatous cholecystitis (n = 25), and gallbladder cancer (n = 18) were reviewed independently by three abdominal radiologists blinded to outcome...
April 14, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29673584/a-30-minutes-supraceliac-aortic-clamping-in-the-rat-causes-death-due-to-an-inflammatory-response-and-pulmonary-lesions
#17
Antoine Monnot, Anaïs Dumesnil, Sylvanie Renet, Marie Laurence Roquet, Vincent Richard, Didier Plissonnier
BACKGROUND: The treatment of thoraco-abdominal aortic aneurysms through an open approach has general and pulmonary consequences of multiple etiologies. Our assumption was that the supraceliac aortic clamping needed for this operation causes a systemic inflammatory response associated with a pulmonary attack. MATERIAL AND METHODS: We developed a model of 30 min supraceliac aortic clamping in Wistar rats weighing 300 g. After 90 min of reperfusion the rats were sacrificed...
April 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29665060/combined-caudal-superficial-epigastric-axial-pattern-flap-and-full-thickness-buccal-mucosa-graft-for-single-stage-preputial-reconstruction-in-six-dogs
#18
F Massari, V Montinaro, P Buracco, G Romanelli
OBJECTIVE: To describe the use of a caudal superficial epigastric flap in combination with a full-thickness oral mucosal/submucosal graft for single-stage reconstruction of extensive preputial defects in dogs. MATERIALS AND METHODS: Medical records of dogs with extensive preputial defects either of traumatic origin or derived from tumour excision were reviewed. In all dogs, the prepuce was reconstructed using a full-thickness oral mucosal/submucosal graft combined with a caudal superficial epigastric axial pattern flap during a single surgical procedure...
April 17, 2018: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/29649831/what-is-the-best-way-to-prepare-a-buccal-mucosa-graft-for-urethroplasty-a-histology-based-preliminary-report
#19
André G Cavalcanti, Carlos F Restrepo, Michele Simões, Waldemar S Costa, Francisco J B Sampaio, Diogo B de Souza
PURPOSE: To evaluate the histological characteristics of buccal mucosa samples prepared using different dissection techniques. METHODS: The buccal mucosae harvested from 9 men submitted to a substitution urethroplasty were used in this study. Biopsy specimens of buccal mucosae were grouped according to the macroscopic appearance after dissection: Group 1 - yellowish appearance (minimal dissection), Group 2 - whitish appearance (more aggressive dissection), and Group 3 - translucent appearance (ultra-aggressive dissection)...
April 12, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29627986/bacterial-cellulose-relieves-diphenoxylate-induced-constipation-in-rats
#20
Xichuan Zhai, Dehui Lin, Yan Zhao, Xingbin Yang
This study was to probe the effects of bacterial cellulose (BC) on diphenoxylate-induced constipation in rats. Administration with BC at 500 mg/kg·bw in diphenoxylate-induced constipation rats distinctly improved the carmine propulsion rate (83.5 ± 5.2%), shortened the defecating time of the first red feces (249.0 ± 23.3 min), and increased the weight of carmine red feces within 5 h (2.7 ± 1.3 g). The levels of aquaporins (AQP-2, AQP-3 and AQP-4) and inhibitory neurotransmitters (nitric oxide, nitric oxide synthetase, vasoactive intestinal peptide and arginine vasopressin) in the BC-treated groups reduced by 31...
April 7, 2018: Journal of Agricultural and Food Chemistry
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