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https://www.readbyqxmd.com/read/29334405/high-resolution-dental-mri-for-planning-palatal-graft-surgery-a-clinical-pilot-study
#1
Tim Hilgenfeld, Thorsten Kästel, Alexander Heil, Peter Rammelsberg, Sabine Heiland, Martin Bendszus, Franz Sebastian Schwindling
AIM: To evaluate whether high-resolution, non-contrast-enhanced dental MRI can be used for accurate determination of palatal-masticatory-mucosa-thickness (PMMT) and to locate the greater palatal artery (GPA). MATERIALS AND METHODS: In five volunteers (4 males, 1 female; mean age 30.2±0.4 years) two independent raters measured PMMT by use of dental MRI in 180 positions. For comparison, clinical bone sounding was performed. The GPA was identified in time-of-flight (TOF) angiography and MSVAT-SPACE-prototype sequence...
January 15, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29334299/mucoadhesive-buccal-film-containing-ornidazole-and-dexamethasone-for-oral-ulcers-in-vitro-and-in-vivo-studies
#2
Chengliang Zhang, Yanan Liu, Wei Li, Ping Gao, Dong Xiang, Xiuhua Ren, Dong Liu
A bilayered mucoadhesive buccal film containing a combination of ornidazole (OD) and dexamethasone sodium phosphate (DEX) was prepared using solvent casting to treat oral ulcers. Films were systematically evaluated in vitro to obtain the optimum formulation. The therapeutic effects of these films were investigated in the rabbit oral ulcer model and the in vivo release of OD and DEX in the human oral cavity was also evaluated. The backing layer contained ethyl cellulose and an optimal mucoadhesive layer containing both OD and DEX was produced...
January 15, 2018: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/29331107/endoscopic-full-thickness-resection-combined-with-laparoscopic-surgery
#3
Chan Gyoo Kim
Endoscopic full-thickness resection combined with laparoscopic surgery was recently developed. These procedures could be categorized as "Cut first and then suture" and "Suture first and then cut". "Cut first and then suture" includes laparoscopic and endoscopic cooperative surgery (LECS) and laparoscopy-assisted endoscopic full-thickness resection (LAEFR). Recent studies have demonstrated the safety and efficacy of LECS and LAEFR. However, these techniques are limited by the related exposure of the tumor and gastric mucosa to the peritoneal cavity and manipulation of these organs, which could lead to viable cancer cell seeding and the spillage of gastric juice into the peritoneal cavity...
January 12, 2018: Clinical Endoscopy
https://www.readbyqxmd.com/read/29283941/tripaddled-anterolateral-thigh-flap-for-the-reconstruction-of-extensively-full-thickness-cheek-defects-by-stacking-two-skin-paddles-as-kiss-pattern
#4
Fei Wang, Pralab Pradhan, Ning Li, Canhua Jiang, Wen Liu, Lijuan Zeng
Extended anterolateral thigh (ALT) flap can provide a large amount of skin to reconstruct the extensively full-thickness defects of cheek. However when the width of 1 skin paddle exceeds 8 cm, it always results in that the donor site cannot be closed primarily and need to be covered by split-thickness skin grafting, which delivers lots of impacts on the functional and cosmetic outcome of the thigh. The aim of this study was to introduce the authors' modification of stacking 2 skin paddles of the tripaddled ALT flap to reconstruct the extensive full-thickness defects in the cheek after the radical ablasion of advanced buccal squamous cell carcinoma...
December 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29280119/-efficacy-of-altemeier-procedure-in-the-treatment-of-rectal-prolapse
#5
Yonglei Cao, Yan Zhou, Congqing Jiang, Guiyi Yang, Hui Song, Lvfeng Liu, Xu Ai, Jing Zhong, Zhilin Gong, Jianhua Ding, Wei Fu, Qun Qian
OBJECTIVE: To evaluate the safety and efficacy of the perineal rectosigmoidectomy (Altemeier procedure) in the treatment of full thickness rectal prolapse. METHODS: Clinical and follow-up data of 52 patients with full thickness rectal prolapse undergoing Altemeier procedure in 9 hospitals from September 2010 to July 2016 were analyzed retrospectively. Of which 38 cases were from Zhongnan Hospital of Wuhan University, 1 case from Suizhou Central Hospital of Hubei province, 1 case from Jingzhou Second People's Hospital of Hubei province, 3 cases from Wuxue First People's Hospital of Hubei province, 1 case from Jingmen First People's Hospital of Hubei province, 1 case from Tuanfeng County Hospital of Hubei province, 4 cases from Jingzhou Central Hospital of Hubei province, 2 from PLA Rocket Army General Hospital, 1 case from the Affiliated Hospital of Xuzhou Medical University in Jiangsu province...
December 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29277972/relationship-of-implant-stability-and-bone-density-derived-from-computerized-tomography-images
#6
Joe Merheb, Marjolein Vercruyssen, Wim Coucke, Marc Quirynen
BACKGROUND AND PURPOSE: Implant stability is one of the most important factors influencing osseointegration. Using stereolithographical guides for maximizing precision, this study aimed at investigating the relationship between implant stability and bone density derived from computerized tomography analysis. MATERIALS AND METHODS: One hundred ninety-five implants were placed in 48 patients using digitally designed stereolithographical surgical guides. Ninety-five implants were placed using a mucosa supported guide and 100 implants were placed using a bone supported guide...
December 26, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29274977/technical-note-changes-in-rumen-mucosa-thickness-measured-by-transabdominal-ultrasound-as-a-noninvasive-method-to-diagnose-subacute-rumen-acidosis-in-dairy-cows
#7
V Neubauer, E Humer, I Kröger, A Meißl, N Reisinger, Q Zebeli
Feeding high-grain diets leads to the release and accumulation of short-chain fatty acids in the rumen. The subsequent prolonged decline in ruminal pH can lead to subacute ruminal acidosis (SARA). Accumulation of short-chain fatty acids can cause proliferation of rumen papillae to increase absorption surface, subsequently leading to a thickening of the rumen mucosa. The aim of this study was to evaluate the appropriateness of continuous measurements of the rumen mucosa thickness (RMT) as a diagnostic tool for SARA in dairy cows compared with continuous measurements of ruminal pH...
December 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29262445/-free-medial-thigh-perforator-flaps-with-various-pedicle-origins-for-the-reconstruction-of-defect-after-buccal-mucosa-squamous-cell-carcinoma-resection
#8
D J Song, Z Li, X Zhou, Y X Zhang, X W Peng, B Zhou, C L Lyu, W Peng, Y Ou
Objective: To explore investigate the application of free medial thigh perforator flaps with different pedicle origins in the reconstruction of defect after radical resection of buccal mucosa squamous cell carcinoma. Methods: From January 2015 to December 2016, 32 cases with buccal mucosa squamous cell carcinoma underwent radical resection and buccal mucosa defect after surgery was reconstructed by free medial thigh perforator flap at the same stage. The patients included 32 males and 5 females, ranged in age from 36 to 71 years (45...
December 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29248711/ultrasound-assessment-of-soft-tissue-augmentation-around-implants-in-the-aesthetic-zone-using-a-connective-tissue-graft-and-xenogeneic-collagen-matrix-1-year-randomised-follow-up
#9
Monika Puzio, Artur Błaszczyszyn, Jakub Hadzik, Marzena Dominiak
PURPOSE: A comparative, ultrasound evaluation of the thickness of keratinized mucosa (TKT) around implants one year after gingival augmentation (GA) by means of a connective tissue graft (CTG) and the xenogeneic collagen matrix (CMX). MATERIALS AND METHODS: A total of 75 bone level tapered implants (Conelog® Camlog) were inserted in 57 patients in the aesthetic area of both jaws. The patients were divided into 3 groups: control group I- without GA; group II- GA 3 months before implantation, and group III- GA 3 months after implantation...
December 14, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29236735/hypertension-in-rats-is-associated-with-an-increased-permeability-of-the-colon-to-tma-a-gut-bacteria-metabolite
#10
Kinga Jaworska, Tomasz Huc, Emilia Samborowska, Leszek Dobrowolski, Klaudia Bielinska, Maciej Gawlak, Marcin Ufnal
An increased blood trimethylamine N-oxide (TMAO) has emerged as a marker of cardiovascular mortality, however, the mechanisms of the increase are not clear. We evaluated if hypertension was associated with changes in the colon permeability to trimethylamine (TMA), a TMAO precursor. We did experiments on male, 24-26-week-old normotensive Wistar-Kyoto rats (WKY), spontaneously hypertensive rats (SHR) and SHR treated with enalapril, an antihypertensive drug (SHR-E). To check the colon permeability and liver TMA clearance, blood was collected from the portal vein and hepatic veins confluence, at baseline and after the intracolonic administration of TMA...
2017: PloS One
https://www.readbyqxmd.com/read/29225457/corneal-regeneration-by-induced-human-buccal-mucosa-cultivated-on-an-amniotic-membrane-following-alkaline-injury
#11
Rohaina Che Man, Then Kong Yong, Ng Min Hwei, Wan Haslina Wan Abdul Halim, Aida Zairani Mohd Zahidin, Roszalina Ramli, Aminuddin Bin Saim, Ruszymah Binti Hj Idrus
Various clinical disorders and injuries, such as chemical, thermal, or mechanical injuries, may lead to corneal loss that results in blindness. PURPOSE: The aims of this study were to differentiate human buccal mucosa (BMuc) into corneal epithelial-like cells, to fabricate engineered corneal tissue using buccal mucosal epithelial cells, and to reconstruct a damaged corneal epithelium in a nude rat model. Methods: BMuc were subjected to 10 d of induction factors to investigate the potential of cells to differentiate into corneal lineages...
2017: Molecular Vision
https://www.readbyqxmd.com/read/29224829/plasticity-of-oral-mucosal-cell-sheets-for-accelerated-and-scarless-skin-wound-healing
#12
Jong-Lyel Roh, Jaewang Lee, Eun Hye Kim, Daiha Shin
OBJECTIVES: Wound healing is generally faster and associated with less scarring in the oral mucosa than in the skin. Although rarely studied, oral mucosa equivalents may contribute to rapid, scarless cutaneous wound healing. Therefore, we examined the potential utility of our newly developed oral mucosal cell sheet in skin wound healing. MATERIALS AND METHODS: Oral mucosa and skin samples were obtained from surgical patients and Sprague-Dawley rats. Keratinocytes and fibroblasts were primarily cultured for in vitro cell expansion...
December 2017: Oral Oncology
https://www.readbyqxmd.com/read/29218772/signals-for-identifying-cows-at-risk-of-subacute-ruminal-acidosis-in-dairy-veterinary-practice
#13
REVIEW
E Humer, J R Aschenbach, V Neubauer, I Kröger, R Khiaosa-Ard, W Baumgartner, Q Zebeli
Controlling rumen disorders is critical to ensure successful dairy herd health management. Lactation diets of dairy cows are commonly rich in concentrates and low in physically effective fibre. Feeding of these diets increases the risk of rumen disorders with far-reaching consequences for cattle health, welfare and sustainability of dairy production. The term subacute ruminal acidosis or SARA is often used as a synonym for poor rumen health. Being subclinical, SARA lacks of clear symptoms and is therefore difficult to diagnose and to control in the practice...
December 8, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29213023/-tracheobronchitis-as-an-extraintestinal-manifestation-of-crohn-s-disease
#14
Ryosuke Sakemi, Suketo So, Yosuke Morimitsu, Tetsuhiro Noda, Kensei Ohtsu, Yoshihiko Karashima, Kentaro Imamura, Hiroya Terabe, Yasuo Chojin, Tatsuji Kato
A 27-year-old woman with Crohn's disease, who had sustained clinical remission for two years following treatment with mesalazine and nutrition therapy, was admitted to our hospital complaining of dry cough, mild dysphagia, and slight fever. A computed tomography of the chest demonstrated an increase in the thickness of the tracheal wall. Bronchoscopy showed a diffusely erythematous and edematous mucosa with whitish granular lesions in the trachea and main carina. Bronchial biopsy specimens showed epithelioid cell granuloma...
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/29212517/is-hematoxylin-eosin-staining-in-rectal-mucosal-and-submucosal-biopsies-still-useful-for-the-diagnosis-of-hirschsprung-disease
#15
Suellen Serafini, Maria Mercês Santos, Ana Cristina Aoun Tannuri, Maria Claudia Nogueira Zerbini, Maria Cecília de Mendonça Coelho, Josiane de Oliveira Gonçalves, Uenis Tannuri
BACKGROUND: Hematoxylin-eosin (HE) staining of a full-thickness rectal wall fragment is classically used for the diagnosis of Hirschsprung disease (HD). However, this technique requires large fragments for a better diagnosis. Additionally, the histochemical and immunohistochemical methods of staining small fragments of rectal mucosal and submucosal biopsies are not available in all centers. Therefore, the possibility of diagnosing HD through HE staining in these biopsies could be a valuable alternative for centers that do not have more specific techniques...
December 6, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/29204575/healing-of-the-nasal-septal-mucosa-in-an-experimental-rabbit-model-of-mucosal-injury
#16
Kyu Young Choi, Sung Woo Cho, Jun-Jae Choi, Yu-Lian Zhang, Dae Woo Kim, Doo Hee Han, Hyun Jik Kim, Dong-Young Kim, Chae-Seo Rhee, Tae-Bin Won
Objective: The aim of this study was to investigate the regeneration process of the nasal mucosa after a surgically created mucosal defect in the rabbit nasal septum, and to evaluate the effects of different interventions. Methods: A 7 mm-diameter circular mucosal defect was made in the septum of forty New Zealand white rabbits. The rabbits were divided into four groups (ten rabbits in each group) according to the type of intervention; no treatment (control), silastic sheet (SS), hyaluronic acid (HA), and silastic sheet and hyaluronic acid (SS + HA) group...
March 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204253/value-of-histomorphometric-tumour-thickness-and-smoothelin-for-conventional-m-classification-in-early-oesophageal-adenocarcinoma
#17
Katharina Endhardt, Bruno Märkl, Andreas Probst, Tina Schaller, Daniela Aust
AIM: To test the validity of tumour thickness measurement in distinguishing between the different infiltration depths, especially when the duplication of muscularis mucosae cannot be demarcated clearly. METHODS: We re-evaluated 100 completely embedded Barrett's adenocarcinomas regarding m-classification, maximum tumour thickness, and muscularis mucosae duplication. For validation, smoothelin staining was performed on a subset of cases. RESULTS: The m1-, m2- and m3-classified adenocarcinomas showed a significant lower tumour thickness compared to the m4- and sm1-classified lesions (P < 0...
November 15, 2017: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29203745/the-use-of-morphological-study-technique-for-investigation-of-labial-and-palatine-glands
#18
Volodymyr H Hryn, Oleg O Sherstyuk, Nataliia L Svintsytska, Аndrij V Piliuhin, Roman L Ustenko
INTRODUCTION: Due to the deterioration of environmental conditions that promotes the onset of inflammatory and autoimmune diseases, and the progress in the diagnosis, the frequency of registration of intercurrent pathology of salivary glands has markedly risen in recent years, demonstrating the increased scientific interest in the research of the common and distinctive features of their structure. THE AIM: The paper was aimed at the development of the method of morphological study of human minor salivary (labial and palatine) glands by the use of plastic wax reconstruction to obtain the plastic model of the acini and ducts of human minor salivary glands...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29196853/immunohistochemical-characterization-of-brush-cells-in-the-rat-larynx
#19
Yoshio Yamamoto, Yuko Ozawa, Takuya Yokoyama, Nobuaki Nakamuta
The immunohistochemical characteristics of brush cells in the laryngeal mucosa were examined using immunohistochemistry for various immunohistochemical cell markers including villin at the light and electron microscopic levels. Cells that were immunoreactive to villin were barrel-shaped with thick cytoplasmic processes extending toward the lumen of the laryngeal cavity. Immunoelectron microscopic observations revealed thick and short microvilli with long rootlets of microfilaments. Numerous small clear vesicles and small finger-like cytoplasmic processes were observed in the apical process and lateral membrane, respectively...
December 1, 2017: Journal of Molecular Histology
https://www.readbyqxmd.com/read/29187222/unusual-presentation-of-plasmablastic-lymphoma-involving-ovarian-mature-cystic-teratoma-a-case-report
#20
Ita Hadžisejdić, Emina Babarović, Luka Vranić, Antica Duletić Načinović, Ksenija Lučin, Maja Krašević, Nives Jonjić
BACKGROUND: Plasmablastic lymphoma (PBL) is relatively new clinical entity described as a distinct subtype of diffuse large B-cell lymphoma (DLBCL). It is characterized by its aggressive nature and proliferation of large neoplastic cells resembling immunoblasts including cells with more obvious plasmacytic differentiation. In this case report, we describe an unexpected finding of PBL associated with a mature cystic teratoma of the ovary in a young immune competent woman. CASE PRESENTATION: A 19-year old woman was admitted to the hospital with generalized lymphadenopathy, a pelvic tumor mass measuring 35 × 30 cm and a 4 cm lump in her right breast...
November 29, 2017: Diagnostic Pathology
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